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Glycogen and amyloid-beta: key players in the shift from neuronal hyperactivity to hypoactivity observed in Alzheimer's disease? 被引量:3
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作者 Britanny Bass Sarah Upson +3 位作者 Kamolika Roy Emily L.Montgomery Tuula O.Jalonen Ian V.J.Murray 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第7期1023-1025,共3页
Introduction:Alzheimer’s disease(AD)begins to develop decades prior to its clinical manifestation(Sperling et al.,2011),and while it is the most common form of dementia,as of yet there is no cure.Two of the most... Introduction:Alzheimer’s disease(AD)begins to develop decades prior to its clinical manifestation(Sperling et al.,2011),and while it is the most common form of dementia,as of yet there is no cure.Two of the most researched pathological features contributing to disease development are the extracellular amyloid plaques composed of amyloid-beta proteins(Aβ)and neurofibrillary tangles of tau proteins.Another feature of AD is the progression of early neuronal excitability/hyperactivity to silencing/hypoactivity(Palop and Mucke,2010), 展开更多
关键词 Glycogen and amyloid-beta key players in the shift from neuronal hyperactivity to hypoactivity observed in Alzheimer’s disease
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Lower bound for the security of differential phase shift quantum key distribution against a one-pulse-attack
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作者 李宏伟 银振强 +3 位作者 王双 鲍皖苏 郭光灿 韩正甫 《Chinese Physics B》 SCIE EI CAS CSCD 2011年第10期46-50,共5页
Quantum key distribution is the art of sharing secret keys between two distant parties, and has attracted a lot of attention due to its unconditional security. Compared with other quantum key distribution protocols, t... Quantum key distribution is the art of sharing secret keys between two distant parties, and has attracted a lot of attention due to its unconditional security. Compared with other quantum key distribution protocols, the differential phase shift quantum key distribution protocol has higher efficiency and simpler apparatus. Unfortunately, the uncondi- tional security of differential phase shift quantum key distribution has not been proved. Utilizing the sharp continuity of the von Neuman entropy and some basic inequalities, we estimate the upper bound for the eavesdropper Eve's infor- mation. We then prove the lower bound for the security of the differential phase shift quantum key distribution protocol against a one-pulse attack with Devatak-Winter's secret key rate formula. 展开更多
关键词 lower bound differential phase shift quantum key distribution
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Breaking chaotic shift key communication via adaptive key identification 被引量:1
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作者 任海鹏 韩崇昭 刘丁 《Chinese Physics B》 SCIE EI CAS CSCD 2008年第4期1202-1208,共7页
This paper proposes an adaptive parameter identification method for breaking chaotic shift key communication from the transmitted signal in public channel. The sensitive dependence property of chaos on parameter misma... This paper proposes an adaptive parameter identification method for breaking chaotic shift key communication from the transmitted signal in public channel. The sensitive dependence property of chaos on parameter mismatch is used for chaos adaptive synchronization and parameter identification. An index function about the synchronization error is defined and conjugate gradient method is used to minimize the index function and to search the transmitter's parameter (key). By using proposed method, secure key is recovered from transmitted signal generated by low dimensional chaos and hyper chaos switching communication. Multi-parameters can also be identified from the transmitted signal with noise. 展开更多
关键词 chaotic shift key adaptive synchronization conjugate gradient method parameter identification
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Key Problems of Cold Power Spinning of Ti-15-3 Alloy 被引量:1
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作者 Debin SHAN Yan LU and Ping LI School of Materials Science and Engineering, Harbin institute of Thchnology, Harbin 150001, China Yi XU Institute of Metal Research, Chinese Academy of Sciences, Shenyang 110015, China 《Journal of Materials Science & Technology》 SCIE EI CAS CSCD 2001年第1期125-126,共2页
The key problems of cold power spinning of Ti-15-3 alloy are studied. Reasonable billet preparation methods are presented to improve crystal structure and avoid crack of billet. Influences of original wall thickness,... The key problems of cold power spinning of Ti-15-3 alloy are studied. Reasonable billet preparation methods are presented to improve crystal structure and avoid crack of billet. Influences of original wall thickness, reduction rate and feed rate on expanding in diameter are analyzed and some methods to prevent expanding in diameter are given. 展开更多
关键词 TI key Problems of Cold Power Spinning of Ti-15-3 Alloy
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Stereoselective Synthesis of 2-(4-Hydroxyphenyl)-3-hydroxymethyl-1,4-benzodioxane-6-aldehyde—The Key Intermediate of Sinaiticin
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作者 Xue Gong SHE Wen Xin GU +1 位作者 Hua WANG Xin Fu PAN(Department of Chemistry,National Laboratory of Applied Oerganic Chemistry,Lanzhou University,Lanzhou 730000) 《Chinese Chemical Letters》 SCIE CAS CSCD 1999年第2期107-108,共2页
2-(4-Hydroxyphenyl)-3-hydroxymethyl-1,4-benzodioxane-6-aldehyde 8,the key intermediate of sinaiticin 10,was synthesized in 6 step from caffeic acid 4 and 4- hydroxybenzsaldehyde 1.the coupling reaction is the key step.
关键词 2-(4-Hydroxyphenyl)-3-hydroxymethyl-1 4-benzodioxane-6-aldehyde key intermediate sinaiticin SYNTHESIS
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KEY WORDS INDEX, RICE SCIENCE, VOL. 13, NO. 1-4, 2006
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《Rice science》 SCIE 2006年第4期I0005-I0006,共2页
关键词 VOL key WORDS INDEX RICE SCIENCE VOL.13 NO.1-4 2006 NO
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KEY WORDS INDEX, RICE SCIENCE, VOL. 14, NOS. 1-4, 2007
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《Rice science》 SCIE 2007年第4期I0005-I0006,共2页
关键词 VOL key WORDS INDEX RICE SCIENCE VOL.14 NOS.1-4 2007 gene NOS
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KEY WORDS INDEX, RICE SCIENCE, VOL. 16, NOS. 1-4, 2009
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《Rice science》 SCIE 2009年第4期I0005-I0006,共2页
关键词 gene NOS key WORDS INDEX RICE SCIENCE VOL.16 NOS.1-4 2009 VOL
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KEY WORDS INDEX, 《RICE SCIENCE》, VOL. 12, NO. 1-4, 2005
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《Rice science》 SCIE 2005年第4期I0007-I0009,共3页
关键词 VOL key WORDS INDEX RICE SCIENCE VOL.12 NO.1-4 2005 NO
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基于USB Key的安全增强密钥生成方案
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作者 赵波 李二辉 +1 位作者 马骏 黄宇晴 《计算机工程与应用》 CSCD 北大核心 2018年第10期135-142,共8页
针对目前嵌入式系统环境下密钥存储安全性不足的问题,提出了一种安全增强密钥(Security-Enhanced Key,SEK)的生成方案。该方案在不改变现有嵌入式系统(Embedded System,ES)架构的前提下,分别利用ES的唯一硬件特征值和USB Key(UK)产生的... 针对目前嵌入式系统环境下密钥存储安全性不足的问题,提出了一种安全增强密钥(Security-Enhanced Key,SEK)的生成方案。该方案在不改变现有嵌入式系统(Embedded System,ES)架构的前提下,分别利用ES的唯一硬件特征值和USB Key(UK)产生的随机数生成各自的密钥种子,之后ES和UK利用密钥种子进行迪菲-赫尔曼协商(Diffie-Hellman Key Exchange,DHKE)生成SEK。SEK仅在需要时生成,使用后即销毁,不需要在嵌入式设备上存储,从根本上提高了密钥的安全性,并在一定程度上解决了嵌入式系统密钥泄漏的安全问题。方案原型的实现和安全性评估表明,在嵌入式系统中加入该方案之后,密钥的安全性得到明显增强,能够抵抗针对嵌入式系统密钥的多种攻击,且增加的额外开销不会对系统性能造成显著影响。 展开更多
关键词 安全增强密钥 嵌入式系统 迪菲-赫尔曼协议 USB key 密钥存储
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TOPO-Ⅱ和GST-π双染色法在非小细胞肺癌研究中的应用
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作者 孙勤暖 王立红 +2 位作者 孙丽华 贺岚 顾岩 《中国肿瘤临床与康复》 2006年第3期207-208,共2页
关键词 非小细胞肺癌(NSCLC) TOPO- GST-Π 双染色法 谷胱甘肽S转移酶-Π DNA拓扑异构酶 抗体检测 分布情况 抗原 key
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USB Key身份认证技术 被引量:7
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作者 王可一 《中国高新技术企业》 2007年第10期101-101,104,共2页
网络应用的安全问题十分重要,本文着重介绍了USB Key身份认证技术的特点、应用方式及基本原理。
关键词 USB key 冲击-响应的双因子认证 数字证书的认证
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Nanoscale mass sensing based on vibration of single-layered graphene sheet in thermal environments 被引量:2
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作者 S.Ahmad Fazelzadeh Esmaeal Ghavanloo 《Acta Mechanica Sinica》 SCIE EI CAS CSCD 2014年第1期84-91,共8页
Based on vibration analysis, single-layered graphene sheet (SLGS) with multiple attached nanoparticles is developed as nanoscale mass sensor in thermal environments. Graphene sensors are assumed to be in simplysuppo... Based on vibration analysis, single-layered graphene sheet (SLGS) with multiple attached nanoparticles is developed as nanoscale mass sensor in thermal environments. Graphene sensors are assumed to be in simplysupported configuration. Based on the nonlocal plate the- ory which incorporates size effects into the classical theory, closed-form expressions lot the frequencies and relative fre- quency shills of SLGS-based mass sensor are derived using the Galerkin method. The suggested model is justified by a good agreement between the results given by the present model and available data in literature. The effects of tem- perature difference, nonlocal parameter, the location of the nanoparticle and the number of nanoparticles on the relative frequency shift of the mass sensor are also elucidated. The obtained results show that the sensitivity of the SLGS- based mass sensor increases with increasing temperature difference. 展开更多
关键词 Vibration - Single-layered graphene sheet. Ther- mal environment - Nonlocal elasticity theory Relative frequency shift
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DFT Studies on Thermal Stabilities,Electronic Structures,and ^(13)C Chemical Shifts of C_(24)O_2 Based on Fullerene C_(24)(D_6) 被引量:2
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作者 王振 张静 《Chinese Journal of Structural Chemistry》 SCIE CAS CSCD 2011年第5期666-671,共6页
Quantum chemical calculations on some possible equilibrium geometries of C24O2 isomers derived from C24 (D6) and C24O have been performed using density functional theory (DFT) method. The geometric and electronic ... Quantum chemical calculations on some possible equilibrium geometries of C24O2 isomers derived from C24 (D6) and C24O have been performed using density functional theory (DFT) method. The geometric and electronic structures as well as the relative energies and thermal stabilities of various C24O2 isomers at the ground state have been calculated at the B3LYP/6-31G(d) level of theory. And the 1,4,2,5-C24O2 isomer was found to be the most stable geometry where two oxygen atoms were added to the longest carbon-carbon bonds in the same pentagon from a thermodynamic point of view. Based on the optimized neutral geometries, the vertical ionization potential and vertical electron affinity have been obtained. Meanwhile, the vibrational frequencies, IR spectrum, and 13C chemical shifts of various C24O2 isomers have been calculated and analyzed. 展开更多
关键词 C24O2 thermal stabilities 13C chemical shifts B3LYP/6-31G(d)
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Maintained Exposure to Spring Water but Not Double Distilled Water in Darkness and Thixotropic Conditions to Weak (~1 µT) Temporally Patterned Magnetic Fields Shift Photon Spectroscopic Wavelengths: Effects of Different Shielding Materials 被引量:2
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作者 N. J. Murugan L. M. Karbowski +1 位作者 R. M. Lafrenie M. A. Persinger 《Journal of Biophysical Chemistry》 2015年第1期14-28,共15页
Spring water but not double-distilled water was exposed, in darkness, to a temporally patterned weak magnetic field that has been shown to affect planarian behavior and slow the rate of cancer cell proliferation. Expo... Spring water but not double-distilled water was exposed, in darkness, to a temporally patterned weak magnetic field that has been shown to affect planarian behavior and slow the rate of cancer cell proliferation. Exposure to the magnetic field caused a reliable shift in the peak (longer) wave-length of ~10 nm for fluorescence emissions and a ~20% increase (~100 counts) in fluorescence intensity. Spectral analyses verified a shift of 5 and 10 nm, equivalent to ~1.5 × 10-20 J “periodicity” across the measured wavelengths, which could reflect a change in the an intrinsic energy as predicted by Del Giudice and Preparata and could correspond to two lengths of O-H bonds. Wrapping the water sample containers during exposure with copper foil, aluminum foil, or plastic altered these fluorescent profiles. The most conspicuous effect was the elimination of a ~280 nm peak in the UV-VIS emission spectra only for samples wrapped with copper foil but not aluminum or plastic. These results suggest that weak magnetic fields produce alterations in the water-ionic complexes sufficient to be reliably measured by spectrophotometry. Because the effect was most pronounced when the spring water was exposed in darkness and was not disturbed the role of thixotropic phenomena and Del Giudice entrapment of magnetic fields within coherent domains of Pollack virtual exclusion zones (EZ) may have set the conditions for subsequent release of the energy as photons. 展开更多
关键词 Water WEAK Magnetic Fields PHOTON Emissions DARKNESS Thixotropic Phenomena Copper Shielding Wavelength shift 10-20 Joules
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Sandwich Complexes of the As_4~(2-) Aromatic Ring with Some Transition Metals
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作者 李志伟 赵存元 +1 位作者 吴文胜 陈六平 《Chinese Journal of Structural Chemistry》 SCIE CAS CSCD 北大核心 2008年第9期1097-1102,共6页
The equilibrium geometries, energies, harmonic vibrational frequencies, and nucleus independent chemical shifts (NICS) of the new type sandwich structures [As4MAs4]^n- (M = Fe, Co, Ni, Ru, Rh, Pd, Os, Ir and Pt; n ... The equilibrium geometries, energies, harmonic vibrational frequencies, and nucleus independent chemical shifts (NICS) of the new type sandwich structures [As4MAs4]^n- (M = Fe, Co, Ni, Ru, Rh, Pd, Os, Ir and Pt; n = 0, 1 or 2) are investigated at the B3LYP level. All the [As4MAs4]^n- species adopt staggered (D4d) conformations as their stable structures and eclipsed (D4h) conformations as their transition states, and once the sandwich complexes are formed, the As4^2- square properties remain unchanged. The NICS calculation confirms that the complexes of Fe, Co, and Ni are aromatic with negative NICS values, and those of Ru, Rh, and lx exhibit slight aromaticity, while those of Pd, Os, and Pt show slight antiaromaticity. 展开更多
关键词 As4^2- dianion AROMATICITY DFT calculation nucleus independent chemical shifts (NICS)
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^(13)C NMR Study of Ethylene/propylene/octene-1 Terpolymers Synthesized with TiCl_4/MgCl_2/ i -Bu_3Al as the Catalyst
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作者 LI San xi ZHOU Zi nan +3 位作者 XIAO Yan wen JING Feng ying PANG De ren HUANG Bao tong 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2000年第3期236-245,共10页
The theory of chemical shift effect of substituent was applied to the assignment of the 13 C NMR spectra of the ethylene/propylene and ethylene/octene 1 copolymers. Using the parameters derived above a... The theory of chemical shift effect of substituent was applied to the assignment of the 13 C NMR spectra of the ethylene/propylene and ethylene/octene 1 copolymers. Using the parameters derived above and the DEPT technique, we then entirely assigned the 13 C NMR spectra of the ethylene/propylene/octene 1 terpolymers synthesized in the presence of the same heterogeneous supported Ziegler Natta catalyst, TiCl 4/MgCl 2/ i Bu 3Al. The present paper also covers the terpolymer composition and the monomer sequence distributions of a series of ethylene/propylene/octene 1 terpolymers. 展开更多
关键词 Chemical shift effect ^(13)C NMR Ethylene/propylene/octene^(-1) terpolymer
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Vitamin A supplement: a key strategy to prevent vitamin A deficiency among young children in Afghanistan
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作者 Ahmad Mujtaba Barekzai Abdullah Sahar Naseer Ahmad Shinwari 《Food Therapy and Health Care》 2022年第2期4-9,共6页
Background:Vitamin A deficiency is the main problem of public health worldwide demonstrated that 190 million population of preschool children and 122 countries(in Africa and South-East Asia)have vitamin A deficiency,a... Background:Vitamin A deficiency is the main problem of public health worldwide demonstrated that 190 million population of preschool children and 122 countries(in Africa and South-East Asia)have vitamin A deficiency,according to recent estimated research.In Afghanistan,vitamin A supplementation is a key strategy to prevent vitamin A deficiency among young children.Children receive vitamin A supplements as part of National Immunization Days(NID)campaigns.Methods:In this case study,the data was collected from June 15/2015 to February 23/2016,and the final report of the Afghanistan Demographic Health Survey(AfDHS)2015 was released on February 15/2017.All 27,209 children aged 6-59 months who are living with their mothers were included in this study.Who consumed foods rich in vitamin A was not included in this study.Results:The percentages who were given vitamin A supplements in the last 6 months among all children 6-59 months aged.A total of 1,572 children aged among 6-8 months were given vitamin A supplements 670(42.6%)children and comparison with the total community of the study(27,209)children(2.46%).A total of 1,148 children aged among 9-11 months were given vitamin A supplements to 465(40.5%)children and comparison with the total community of the study(27,209)children(1.70%).Conclusion:After following up on more studies,we found that vitamin A deficiency is a public problem,thus it is better to use wheat flour fortification,vitamin A capsule(VAC)supplementation,nutrition education,source of vitamin A,and training of primary healthcare workers on the clinical to prevent and treat the vitamin A deficiency among children.Therefore,we aimed to determine the given vitamin A supplementation among children aged 6-59 months in 33 provinces in Afghanistan,in 2015. 展开更多
关键词 vitamin A deficiency SUPPLEMENT children age 6-59 months key strategy
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科技期刊“关键词”编写格式规范建议 被引量:1
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作者 谢文亮 冯婷 《肇庆学院学报》 2023年第2期124-128,共5页
科技期刊中“关键词”一词有两种不同表达:Key words和Keywords,虽然编写形式不统一,没有造成太多文本分析的歧义,但给期刊规范、文献检索和作者写作带来不便,必须对其进行统一规范根据已有的公开的文献.,分析了Keywords和Keywords在英... 科技期刊中“关键词”一词有两种不同表达:Key words和Keywords,虽然编写形式不统一,没有造成太多文本分析的歧义,但给期刊规范、文献检索和作者写作带来不便,必须对其进行统一规范根据已有的公开的文献.,分析了Keywords和Keywords在英文中的定义、功能以及应用,对Keywords和Keywords的发展历史进行溯源后发现,Key word逐渐被Keyword所替代,并且从1995年后出版的字典中,再也没有出现过Key word的词条,其替代原因是科技论文发表数量剧增、科技论文交流的需要以及网络信息检索的兴起,使得Keyword成为信息检索和科技论文“关键词”的代号结合计算机信息检索和科技期刊中关键词的作用,对比结合GB/T7713-1987中对“关键词”的定义,提出使用Keywords作为科技期刊“关键词”一词的原因. 展开更多
关键词 科技期刊 关键词 信息检索 key words keyWORDS GB/T 7713-1987
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Investigation on the Structure of Chute-feed and Card Auto-leveller and Their Selection of Technological Processes
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作者 程隆棣 《Journal of China Textile University(English Edition)》 EI CAS 1998年第3期62-65,共4页
Based on the structure of chute - feed and autoleveHer, an analysis of their working principle and the verification of their practical production results have been carried out. Finally, the future investigation direet... Based on the structure of chute - feed and autoleveHer, an analysis of their working principle and the verification of their practical production results have been carried out. Finally, the future investigation direetiom of chute - feed and card autuleveller are put forward. 展开更多
关键词 CHUTE - FEED CARD AUTO - leveller IRREGULARITY among shifts.
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