Effect of power supply parameters on discharge characteristics and sterilization efficiency of magnetically driven rotating gliding arc

Plasma sterilization is a new generation of high-tech sterilization method that is fast,safe,and pollution free.It is widely used in medical,food,and environmental protection fields.Home air sterilization is an emerging field of plasma application,which puts higher requirements on the miniaturization,operational stability,and operating cost of plasma device.In this study,a novel magnetically driven rotating gliding arc(MDRGA)discharge device was used to sterilize Lactobacillus fermentation.Compared with the traditional gas-driven gliding arc,this device has a simple structure and a more stable gliding arc.Simulation using COMSOL Multiphysics showed that adding permanent magnets can form a stable magnetic field,which is conducive to the formation of gliding arcs.Experiments on the discharge performance,ozone concentration,and sterilization effect were conducted using different power supply parameters.The results revealed that the MDRGA process can be divided into three stages:starting,gliding,and extinguishing.Appropriate voltage was the key factor for stable arc gliding,and both high and low voltages were not conducive to stable arc gliding and ozone production.In this experimental setup,the sterilization effect was the best at 6.6 kV.A high modulation duty ratio was beneficial for achieving stable arc gliding.However,when the duty ratio exceeded a certain value,the improvement in the sterilization effect was slow.Therefore,considering the sterilization effect and energy factors comprehensively,we chose 80%as the optimal modulation duty ratio for this experimental device.

Data-driven modeling on anisotropic mechanical behavior of brain tissue with internal pressure

Brain tissue is one of the softest parts of the human body,composed of white matter and grey matter.The mechanical behavior of the brain tissue plays an essential role in regulating brain morphology and brain function.Besides,traumatic brain injury(TBI)and various brain diseases are also greatly influenced by the brain's mechanical properties.Whether white matter or grey matter,brain tissue contains multiscale structures composed of neurons,glial cells,fibers,blood vessels,etc.,each with different mechanical properties.As such,brain tissue exhibits complex mechanical behavior,usually with strong nonlinearity,heterogeneity,and directional dependence.Building a constitutive law for multiscale brain tissue using traditional function-based approaches can be very challenging.Instead,this paper proposes a data-driven approach to establish the desired mechanical model of brain tissue.We focus on blood vessels with internal pressure embedded in a white or grey matter matrix material to demonstrate our approach.The matrix is described by an isotropic or anisotropic nonlinear elastic model.A representative unit cell(RUC)with blood vessels is built,which is used to generate the stress-strain data under different internal blood pressure and various proportional displacement loading paths.The generated stress-strain data is then used to train a mechanical law using artificial neural networks to predict the macroscopic mechanical response of brain tissue under different internal pressures.Finally,the trained material model is implemented into finite element software to predict the mechanical behavior of a whole brain under intracranial pressure and distributed body forces.Compared with a direct numerical simulation that employs a reference material model,our proposed approach greatly reduces the computational cost and improves modeling efficiency.The predictions made by our trained model demonstrate sufficient accuracy.Specifically,we find that the level of internal blood pressure can greatly influence stress distribution and determine the possible related damage behaviors.

Effects of counter-current driven by electron cyclotron waves on neoclassical tearing mode suppression

Through theoretical analysis,we construct a physical model that includes the influence of counter-external driven current opposite to the plasma current direction in the neoclassical tearing mode(NTM).The equation is used with this model to obtain the modified Rutherford equation with co-current and counter-current contributions.Consistent with the reported experimental results,numerical simulations have shown that the localized counter external current can only partially suppress NTM when it is far from the resonant magnetic surface.Under some circumstances,the Ohkawa mechanism dominated current drive(OKCD)by electron cyclotron waves can concurrently create both co-current and counter-current.In this instance,the minimal electron cyclotron wave power that suppresses a particular NTM was calculated by the Rutherford equation.The result is marginally less than when taking co-current alone into consideration.As a result,to suppress NTM using OKCD,one only needs to align the co-current with a greater OKCD peak well with the resonant magnetic surface.The effect of its lower counter-current does not need to be considered because the location of the counter-current deviates greatly from the resonant magnetic surface.

Research on the Microstructure Construction Technology of Fully Degraded Polymer Vascular Stent Based on Electric Field Driven 3D Printing

The so-called fourth-generation biodegradable vascular stent has become a research hotspot in thefield of bioengineering because of its good degradation ability and drug-loading characteristics.However,the preparationof polymer-degraded vascular stents is affected by known problem such as poor processflexibility,low formingaccuracy,large diameter wall thickness,limited complex pore structure,weak mechanical properties of radial support and high process cost.In this study,a deposition technique based on a high-voltage electric-field-driven continuous rotating jet is proposed to fabricate fully degraded polymer vascular stents.The experimental results showthat,due to the rotation of the deposition axis,the deposition direction of PCL(polycaprolactone)micro-jet isalways tangent to the surface of the deposition axis.The direction of the viscous drag force is also consistent withthe deposition direction of the jet.It is shown that by setting different rotation speeds of deposition axisωandlinear motion speeds of the nozzle V,the direction of rotation,pitch and angle of the individual printed spiralcurve can be precisely tuned.In the process of multiple spiral curves matching the deposition forming thin walltube mesh,the mesh shape and size of the thin wall tube can be accurately controlled by changing the number ofmatching spiral curves and the size of the matching position bias distance.Finally,the characteristics of a PCLtubular stent sample(with uniform-size microfibers and mesh shape),fabricated under the appropriate processparameters are described in detail.

Data-model coupling driven stress field measurements

This paper presents a method for measuring stress fields within the framework of coupled data models,aimed at determining stress fields in isotropic material structures exhibiting localized deterioration behavior without relying on constitutive equations in the deteriorated region.This approach contributes to advancing the field of intrinsic equation-free mechanics.The methodology combines measured strain fields with data-model coupling driven algorithms.The gradient and Canny operators are utilized to process the strain field data,enabling the determination of the deterioration region's location.Meanwhile,an adaptive model building method is proposed for constructing coupling driven models.To address the issue of unknown datasets during computation,a dataset updating strategy based on a differential evolutionary algorithm is introduced.The resulting optimal dataset is then used to generate stress field results.Validation against finite element method calculations demonstrates the accuracy of the proposed method in obtaining full-field stresses in specimens with local degradation behavior.

Investigation of system parameters towards safer impact based shock-to-detonation transition in a novel laser driven flyer plate prototype

Laser driven flyer plate technology offers improved safety and reliability for detonation of explosives in industrial applications ranging from mining and stone quarrying to the aerospace and defense industries.This study is based on developing a safer laser driven flyer plate prototype comprised of a laser initiator and a flyer plate subsystem that can be used with secondary explosives.System parameters were optimized to initiate the shock-to-detonation transition(SDT)of a secondary explosive based on the impact created by the flyer plate on the explosive surface.Rupture of the flyer was investigated at the mechanically weakened region located on the interface of these subsystems,where the product gases from the deflagration of the explosive provide the required energy.A bilayer energetic material was used,where the first layer consisted of a pyrotechnic component,zirconium potassium perchlorate(ZPP),for sustaining the ignition by the laser beam and the second layer consisted of an insensitive explosive,cyclotetramethylene-tetranitramine(HMX),for deflagration.A plexiglass interface was used to enfold the energetic material.The focal length of the laser beam from the diode was optimized to provide a homogeneous beam profile with maximum power at the surface of the ZPP.Closed bomb experiments were conducted in an internal volume of 10 cm^(3) for evaluation of performance.Dependency of the laser driven flyer plate system output on confinement,explosive density,and laser beam power were analyzed.Measurements using a high-speed camera resulted in a flyer velocity of 670±20 m/s that renders the prototype suitable as a laser detonator in applications,where controlled employment of explosives is critical.

Data Driven Vibration Control:A Review

With the ongoing advancements in sensor networks and data acquisition technologies across various systems like manufacturing,aviation,and healthcare,the data driven vibration control(DDVC)has attracted broad interests from both the industrial and academic communities.Input shaping(IS),as a simple and effective feedforward method,is greatly demanded in DDVC methods.It convolves the desired input command with impulse sequence without requiring parametric dynamics and the closed-loop system structure,thereby suppressing the residual vibration separately.Based on a thorough investigation into the state-of-the-art DDVC methods,this survey has made the following efforts:1)Introducing the IS theory and typical input shapers;2)Categorizing recent progress of DDVC methods;3)Summarizing commonly adopted metrics for DDVC;and 4)Discussing the engineering applications and future trends of DDVC.By doing so,this study provides a systematic and comprehensive overview of existing DDVC methods from designing to optimizing perspectives,aiming at promoting future research regarding this emerging and vital issue.

磁驱动固体套筒实验模拟中的电流系数

采用不可压缩理论模型,对FP-2装置上开展的磁驱动固体套筒实验进行了模拟分析。模拟结果表明,无论是二维磁流体力学理论模型,还是其他不可压缩理论模型,回流罩结构磁驱动固体套筒的边界磁感应强度公式中都包含一个小于1的套筒电流系数。对不同套筒厚度、不同套筒半径条件下磁驱动固体套筒实验的电流系数进行了模拟,发现电流系数不仅与套筒内半径有关,还与套筒厚度有关;套筒内半径越大,套筒电流系数越小;套筒厚度越大,套筒电流系数越小。准确掌握磁驱动固体套筒电流系数的变化规律,可使磁流体程序从磁驱动固体套筒实验的后验模拟发展为精确预测,使磁流体力学模型真正具备正确设计和指导磁驱动固体套筒相关实验的理论能力。

Material driven workability simulation by FEM including 3D processing maps for magnesium alloy

The three-dimensional （3D） processing maps considering strain based on the two-dimensional （2D） processing maps proposed by PRASAD can describe the distribution of the efficiency of power dissipation and flow instability regions at various temperatures, strain rates and strains, which exhibit intrinsic workability related to material itself. Finite element （FE） simulation can obtain the distribution of strain, strain rate, temperature and die filling status, which indicates state-of-stress （SOS） workability decided by die shape and different processing conditions. On the basis of this, a new material driven analysis method for hot deformation was put forward by the combination of FE simulation with 3D processing maps, which can demonstrate material workability of the entire hot deformation process including SOS workability and intrinsic workability. The hot forging process for hard-to-work metal magnesium alloy was studied, and the 3D thermomechanical FE simulation including 3D processing maps of complex hot forging spur bevel gear was first conducted. The hot forging experiments were carried out. The results show that the new method is reasonable and suitable to determine the aoorooriate nrocess narameters.

ARCHITECTURE OF DYNAMIC DATA DRIVEN SIMULATION FOR WILDFIRE AND ITS REALIZATION

Dynamic data driven simulation （DDDS） is proposed to improve the model by incorporaing real data from the practical systems into the model. Instead of giving a static input, multiple possible sets of inputs are fed into the model. And the computational errors are corrected using statistical approaches. It involves a variety of aspects, including the uncertainty modeling, the measurement evaluation, the system model and the measurement model coupling ,the computation complexity, and the performance issue. Authors intend to set up the architecture of DDDS for wildfire spread model, DEVS-FIRE, based on the discrete event speeification （DEVS） formalism. The experimental results show that the framework can track the dynamically changing fire front based on fire sen- sor data, thus, it provides more aecurate predictions.

区域一体化与企业数字化转型——基于市场竞争和创新驱动的视角

通过以长三角区域一体化试点政策为准自然实验,利用2008—2021年沪深A股上市企业的数据,考察了区域一体化政策对企业数字化转型的影响和内在机理。研究发现,区域一体化政策能够显著提升企业数字化水平,该结论在稳健性检验后仍然成立。从不同维度来看,区域一体化政策显著促进了数字技术发展的深度(底层数字技术应用)和融合发展的广度(智能制造和互联网商业模式)。机制检验表明,区域一体化政策改善了宏观层面的市场竞争环境和创新环境,从而增强了企业面临的赶超压力和驱动企业进行创新策略调整,进而提升企业数字化水平。异质性分析表明,区域一体化政策的数字化发展效应主要存在于国有企业、成长型企业、数字金融发展水平高和知识产权保护重视程度高的地区。进一步研究显示,区域一体化政策不仅促进了企业专业化分工,同时改善了企业资源错配。研究结论不仅为化解企业数字化转型困境提供了经验证据,也为政府深入推进区域一体化协调发展和构建统一大市场提供参考。

场驱动医疗微机器人:材料制备工艺不断优化的应用前景

背景:微机器人具有体积小、灵活、靶向性强等特点,可以在狭窄的环境下通过单体或集群的方式完成复杂的工作。随着材料、制备工艺以及驱动方式的不断优化,其在生物医学领域内显示出越来越重要的应用价值。目的:分析场驱动微机器人在生物医学领域的应用并展望其应用前景。方法:以“微机器人,纳米机器人,驱动,生物医学,医疗”为中文关键词,以“microrobots,micro-robots,nanorobots,micromachine,microswimmer,medical”为英文关键词,分别检索万方以及Pub Med数据库,检索时间范围重点为2010年1月至2024年1月,同时纳入少数远期文献。通过阅读文题、摘要初步筛选,排除重复性研究、低质量期刊以及与内容不相关的文献,阅读全文后最终纳入66篇文献进行综述。结果与结论:场驱动医疗微机器人涵盖了磁、光、热、超声及多种混合因素驱动机器人。场驱动机器人已被应用于肠道诊断、药物靶向治疗及干细胞治疗等多个领域。尽管医用微机器人在临床医学中已有少数应用,但大多数还处于理论和实验阶段。医用微机器人的未来面临诸多挑战,如实现大规模制备、进一步提升精确控制、解决回收或体内降解问题,以及所用材料是否会对人体产生不良反应等,此外微机器人还需与相应的微创医学手术相配合。

Full field reservoir modeling of shale assets using advanced data-driven analytics

Hydrocarbon production from shale has attracted much attention in the recent years. When applied to this prolific and hydrocarbon rich resource plays, our understanding of the complexities of the flow mechanism（sorption process and flow behavior in complex fracture systems- induced or natural） leaves much to be desired. In this paper, we present and discuss a novel approach to modeling, history matching of hydrocarbon production from a Marcellus shale asset in southwestern Pennsylvania using advanced data mining, pattern recognition and machine learning technologies. In this new approach instead of imposing our understanding of the flow mechanism, the impact of multi-stage hydraulic fractures, and the production process on the reservoir model, we allow the production history, well log, completion and hydraulic fracturing data to guide our model and determine its behavior. The uniqueness of this technology is that it incorporates the so-called ＂hard data＂ directly into the reservoir model, so that the model can be used to optimize the hydraulic fracture process. The ＂hard data＂ refers to field measurements during the hydraulic fracturing process such as fluid and proppant type and amount, injection pressure and rate as well as proppant concentration. This novel approach contrasts with the current industry focus on the use of ＂soft data＂（non-measured, interpretive data such as frac length, width,height and conductivity） in the reservoir models. The study focuses on a Marcellus shale asset that includes 135 wells with multiple pads, different landing targets, well length and reservoir properties. The full field history matching process was successfully completed using this data driven approach thus capturing the production behavior with acceptable accuracy for individual wells and for the entire asset.

Optimum path planning of mobile robot in unknown static and dynamic environments using Fuzzy-Wind Driven Optimization algorithm

This article introduces a singleton type-1 fuzzy logic system(T1-SFLS) controller and Fuzzy-WDO hybrid for the autonomous mobile robot navigation and collision avoidance in an unknown static and dynamic environment. The WDO(Wind Driven Optimization) algorithm is used to optimize and tune the input/output membership function parameters of the fuzzy controller. The WDO algorithm is working based on the atmospheric motion of infinitesimal small air parcels navigates over an N-dimensional search domain. The performance of this proposed technique has compared through many computer simulations and real-time experiments by using Khepera-Ⅲ mobile robot. As compared to the T1-SFLS controller the Fuzzy-WDO algorithm is found good agreement for mobile robot navigation.

Dynamic modeling of wave driven unmanned surface vehicle in longitudinal profile based on D-H approach

Wave driven unmanned surface vehicle(WUSV) is a new concept ocean robot drived by wave energy and solar energy,and it is very suitable for the vast ocean observations with incomparable endurance.Its dynamic modeling is very important because it is the theoretical foundation for further study in the WUSV motion control and efficiency analysis.In this work,the multibody system of WUSV was described based on D-H approach.Then,the driving principle was analyzed and the dynamic model of WUSV in longitudinal profile is established by Lagrangian mechanics.Finally,the motion simulation of WUSV and comparative analysis are completed by setting different inputs of sea state.Simulation results show that the WUSV dynamic model can correctly reflect the WUSV longitudinal motion process,and the results are consistent with the wave theory.

Super enhancer inhibitors suppress MYC driven transcriptional amplification and tumor progression in osteosarcoma

Osteosarcoma is the most common primary bone sarcoma that mostly occurs in young adults. The causes of osteosarcoma are heterogeneous and still not fully understood. Identification of novel, important oncogenic factors in osteosarcoma and development of better, effective therapeutic approaches are in urgent need for better treatment of osteosarcoma patients. In this study, we uncovered that the oncogene MYC is significantly upregulated in metastastic osteosarcoma samples. In addition, high MYC expression is associated with poor survival of osteosarcoma patients. Analysis of MYC targets in osteosarcoma revealed that most of the osteosarcoma super enhancer genes are bound by MYC. Treatment of osteosarcoma cells with super enhancer inhibitors THZ1 and JQ1 effectively suppresses the proliferation, migration, and invasion of osteosarcoma cells. Mechanistically,THZ1 treatment suppresses a large group of super enhancer containing MYC target genes including CDK6 and TGFB2. These findings revealed that the MYC-driven super enhancer signaling is crucial for the osteosarcoma tumorigenesis and targeting the MYC/super enhancer axis represents as a promising therapeutic strategy for treatment of osteosarcoma patients.

Electrically driven single-photon sources

Single-photon sources are building blocks for photonic quantum information processes. Of the many single-photon generation schemes, electrically driven single-photon sources have the advantages of realizing monolithic integration of quantum light sources and detectors without optical filtering, thus greatly simplify the integrated quantum photonic circuits. Here, we review recent advances on electrically driven single-photon sources based on solid-state quantum emitters, such as semiconductor epitaxial quantum dots, colloidal quantum dots, carbon nanotubes, molecules, and defect states in diamond, SiC and layered semiconductors. In particular, the merits and drawbacks of each system are discussed. Finally, the article is concluded by discussing the challenges that remain for electrically driven single-photon sources.

Study and Measurement of Glidarc Driven by Magnetic Field

Non-thermal plasma at atmosphere was generated through glidarc discharge driven by magnetic field and observed by using a high speed charge coupled device （CCD） and photo multiplier tube （PMT）. The arc diameter projecting in the direction of arc motion （front-viewed diameter） and the diameter projecting in the perpendicular direction of arc motion （side-viewed diameter） were measured. The effect of both the arc current and the magnetic field was analysed. The front-viewed diameter was compared with the side-viewed one. Simultaneously the electricfield intensity was measured directly and analysed by considering the effect of the external magnetic field and arc current.

Phenomenon of methane driven caused by hydraulic fracturing in methane-bearing coal seams

The methane concentration of the return current will always be enhanced to a certain degree when hydraulic fracturing with bedding drilling is implemented to a gassy coal seam in an underground coal mine. The methane in coal seam is driven out by hydraulic fracturing. Thus, the phenomenon is named as methane driven effect of hydraulic fracturing. After deep-hole hydraulic fracturing at the tunneling face of the gassy coal seam, the coal methane content exhibits a ‘‘low-high-low" distribution along excavation direction in the following advancing process, verifying the existence of methane driven caused by hydraulic fracturing in methane-bearing coal seam. Hydraulic fracturing causes the change of pore-water and methane pressure in surrounding coal. The uneven distribution of the pore pressure forms a pore pressure gradient. The free methane migrates from the position of high pore(methane) pressure to the position of low pore(methane) pressure. The methane pressure gradient is the fundamental driving force for methane-driven coal seam hydraulic fracturing. The uneven hydraulic crack propagation and the effect of time(as some processes need time to complete and are not completed instantaneously) will result in uneven methane driven. Therefore, an even hydraulic fracturing technique should be used to avoid the negative effects of methane driven; on the other hand, by taking fully advantage of methane driven, two technologies are presented.

Ratchet transport of overdamped particles in superimposed driven lattices

Ratchet transport of overdamped particles is investigated in superimposed driven lattices using Langevin dynamics simulations. It is found that noise can strongly affect the transport of the particles. When lattices driving dominates the transport, the noise acts as a disturbance of the directed transport and slows down the average velocity of the particles.When the driving phase has less impact on particle transport, Gaussian white noise can play a positive role. By simply modulating these two parameters, we can control efficiency and the direction of the directed currents.