期刊文献+
共找到495篇文章
< 1 2 25 >
每页显示 20 50 100
Neonatal Infection among Women with Prior Premature Labor
1
作者 Tandu-Umba Barthélémy Kalonji Tshianyi David 《Open Journal of Obstetrics and Gynecology》 2015年第15期833-838,共6页
Objectives: Since studies demonstrate that neonates born to mothers having been cared for premature labor will suffer from congenital neonatal sepsis, we aimed to evaluate the prevalence and main risk factors of neona... Objectives: Since studies demonstrate that neonates born to mothers having been cared for premature labor will suffer from congenital neonatal sepsis, we aimed to evaluate the prevalence and main risk factors of neonatal infection among mothers having experienced a prior premature labor. Methods: This was a cross sectional study carried out from January 1st throughout 31st December, 2013 at the university clinics of Kinshasa. It concerned all delivered women at term having been cared for premature labor prior to giving birth a live newborn. Maternal variables of interest were: parity, gestation, age, intrapartum fever, malaria, urogenital infection during the last 2 weeks before delivery (UGI), premature rupture of membranes (PROM), cervical cerclage, meconium-stained amniotic fluid (MSAF) and the way of delivery. For neonates attention was paid on gestational age, birth weight, admission at neonatal intensive care unit (ANICU) and infection as stated within three days after birth. T-test and Chi-square were used where appropriate. Logistic analysis was used to determine the risk for maternal variables to induce neonatal infection (OR and CI), the significance stated at p < 0.05. Results: Fifty two mother-infant couples were recruited. Of these 19 neonates were infected (prevalence of 36.5%). Mean age, gestational age and birth weight were 30.19 ± 5.32 years, 37.2 ± 2 weeks and 2638 ± 588 g, respectively. Infected neonates had their gestational age and birth weight significantly lower whilst proportion of ANICU higher than that on non infected. Prematurity, PROM, UGI, prior cerclage and MSAF were significantly more frequent in couples with neonatal infection. Prematurity, birth weight <2500 g and UGI were found to enhance the risk by 3 to 4 times. Conclusion: The prevalence of neonatal infection was very high. Prematurity, birth weight <2500 g and maternal UGI were found to enhance the risk by 3 to 4 times. 展开更多
关键词 Prior premature labor MATERNAL UROGENITAL INFECTION NEONATAL INFECTION Risk Factors
下载PDF
Terminal Pregnancy Complicated by Measles and Premature Labor:a Case Report
2
作者 Yu-chen Zhang Li Liu Xiao-li Yang 《国际感染病学(电子版)》 CAS 2013年第2期88-89,共2页
Measles infection in pregnant women is a very dangerous clinical condition.Patients usually had complicated pneumonia,and virus could pass through the placenta to the fetus and lead to premature delivery,stillbirth,mi... Measles infection in pregnant women is a very dangerous clinical condition.Patients usually had complicated pneumonia,and virus could pass through the placenta to the fetus and lead to premature delivery,stillbirth,miscarriage and neonatal measles.In this report,one such case,which was diagnosed by clinical signs and symptoms,clinical and laboratory examination was described.After proper therapeutic treatment,the infection was well-controlled and a baby was born by nature labor. 展开更多
关键词 Pregnancy trimester third MEASLES Obstetric labor premature
下载PDF
Prevention and not merely prediction of preterm labor and delivery 被引量:1
3
作者 Yves Jacquemyn 《World Journal of Obstetrics and Gynecology》 2012年第3期17-19,共3页
Different methods have been proposed to screen for preterm labor and delivery; most of these aim to pre-dict the risk that preterm delivery is going to take place. However, interesting though this knowledge might be, ... Different methods have been proposed to screen for preterm labor and delivery; most of these aim to pre-dict the risk that preterm delivery is going to take place. However, interesting though this knowledge might be, knowing the future is of no use when no changes can be made. Recent publications have suggested new and exciting modalities to actually diminish the frequency of preterm birth in patients selected by transvaginal cervical length measurement; these modalities include vaginal progesterone and vaginal pessaries. Although promising, many questions remain to be answered; not least about the long term outcome for both neonates and mothers, but also on the eventual introduction of such strategies to the general obstetric population. One of the main problems that urgently needs clarifcation is how we are going to offer this best of medicine to those needing it most: deprived and socially isolated women who have the highest risk for preterm laborand delivery, probably not due to any congenital cervi-cal problems, but to a combination of environmental, microbiological and social factors, including transgen-erational poverty and deprivation. 展开更多
关键词 Preterm labor Cervical length PREVENTION prematurITY PROGESTERONE
下载PDF
Current Status of Stem Cells in the Treatment of Premature Ovarian Failure
4
作者 Guojie Ji Huanhuan Hu +3 位作者 Rui Liu Guanjie Li Jiangshan Zhao Huigen Feng 《Journal of Biosciences and Medicines》 2024年第7期263-280,共18页
Premature ovarian failure (POF) is a prevalent cause of female infertility. POF features include estrogen hypofunction, amenorrhea, infertility, and high gonadotropin levels. The etiology of POF is genetic diseases, a... Premature ovarian failure (POF) is a prevalent cause of female infertility. POF features include estrogen hypofunction, amenorrhea, infertility, and high gonadotropin levels. The etiology of POF is genetic diseases, autoimmune diseases, enzyme defects and environmental factors. The development of Regenerative medicine has made stem cell and exosome (EXOs) therapy effective for POF. This review discusses POF stem cell research and development. 展开更多
关键词 etiology INFERTILITY premature Ovarian Failure Regenerative Medicine Stem Cells
下载PDF
Recent Research Progress in Premature Ovarian Failure
5
作者 Yaping Meng Xi Xia +3 位作者 Wenjie Jiang Minghui Hao Ziqi Fan Yihang Song 《Journal of Clinical and Nursing Research》 2024年第7期274-281,共8页
Premature ovarian failure refers to ovarian function failure in women before the age of 40 years due to follicular depletion or follicular dysfunction resulting in abnormal hormone levels.The etiology and pathogenesis... Premature ovarian failure refers to ovarian function failure in women before the age of 40 years due to follicular depletion or follicular dysfunction resulting in abnormal hormone levels.The etiology and pathogenesis of premature ovarian failure may be related to genetic,immunological,medical,environmental,infectious,psychological and enzyme deficiencies.The treatment involves Western medicine,Chinese medicine,and a combination of Chinese and Western medicine,and the treatment level includes hormone level,cellular level,surgery and psychological aspect.This paper would like to review the progress of the etiology,pathogenesis and treatment of premature ovarian failure in recent years. 展开更多
关键词 premature ovarian failure etiology PATHOGENESIS TREATMENT
下载PDF
Progress in treatment of premature ovarian failure using Chinese andwestern medicine
6
作者 Wen-Ming Cao Shu-Ling Zhang +2 位作者 Yan-Ling Li Yu Na Xin-Liang He 《Psychosomatic Medicine Research》 2020年第4期136-143,共8页
Premature ovarian failure (POF) refers to ovarian failure in patients before the age of 40, which is manifested by aseries of symptoms such as hot flashes, hyperhidrosis, facial flushing, low sexual desire, amenorrhea... Premature ovarian failure (POF) refers to ovarian failure in patients before the age of 40, which is manifested by aseries of symptoms such as hot flashes, hyperhidrosis, facial flushing, low sexual desire, amenorrhea, etc.Gynecological endocrine tests show that estrogen level of patients decreases while follicle stimulating hormonelevel increases, affecting pregnancy of women of childbearing age and seriously causing changes in the quality oflife of patients. The causes of POF are complex with poor therapeutic effect, which seriously endangers thephysical and mental health of patients. This paper summarized the a general description of Chinese medicine (CM)and Western medicine (WM) treating POF from the aspects of clinical application according to the existingliterature. Although WM can significantly contribute to the treatment of POF, the side effects are serious bylong-term application. CM has unique advantages, including reduced adverse reactions and higher patientcompliance. It may also fill in the shortcomings of WM in the intermittent period treatment of POF. Thecombination of Chinese and western medicine has proven to become an important direction for POF treatment. 展开更多
关键词 premature ovarian failure etiology Research progress Chinese medicine Western medicine
下载PDF
Factors of Fetal Origin in the Regulation of Labor Initiation and Preterm Birth
7
作者 Longkun Ding Lu Gao 《Maternal-Fetal Medicine》 CSCD 2023年第4期238-243,共6页
Preterm birth is the leading cause of mortality and morbidity in newborns and children under 5 years-of-age.In order to improve the survival rate and quality of preterm infants,there is critical need to identify the s... Preterm birth is the leading cause of mortality and morbidity in newborns and children under 5 years-of-age.In order to improve the survival rate and quality of preterm infants,there is critical need to identify the specific mechanisms underlying the initiation of labor.Pregnancy represents a period of constant interactive dialog between mother and fetus.A disturbance in the pattern of maternal-fetal communication can induce physiological or pathological labor.Although a number of studies have investigated the contributions of maternal factors to the initiation of labor,the concept that fetal organ development and maternal adaptation are coordinated has emerged over recent years,thus emphasizing that factors of fetal origin may serve as hormonal signals for the initiation of labor.In this review,we summarize and discuss several specific mechanisms by which factors of fetal origin may influence parturition during term or preterm labor,including the specific regulation of fetal organs,including the lungs and accessory organs during pregnancy.Future research may focus on the specific pathways by which signals from the fetal lungs and other fetal organs interact with the maternal system to initiate eventual labor. 展开更多
关键词 premature birth Fetal origin factor PLACENTA Fetal membrane PARTURITION Term labor
原文传递
Preterm Labor,a Syndrome Attributed to the Combination of External and Internal Factors
8
作者 Yuanyuan Liu Lu Gao 《Maternal-Fetal Medicine》 2022年第1期61-71,共11页
Preterm labor(before 37 weeks’gestation)is the leading cause of neonatal mortality and morbidity,which can be divided into iatrogenic preterm labor,infectious preterm labor,and spontaneous preterm labor(sPTL).Up to n... Preterm labor(before 37 weeks’gestation)is the leading cause of neonatal mortality and morbidity,which can be divided into iatrogenic preterm labor,infectious preterm labor,and spontaneous preterm labor(sPTL).Up to now,there continue to be great difficulties in prediction and prevention of sPTL,owing to multiple risk factors,pathogenesis,and pathologic processes contributing to the event,which have not been fully clarified.Pregnancy maintenance and parturition is a complicated process with continuous maternal-fetal dialogue,in which both maternal and fetal factors participate and affect the outcome of pregnancy,including sPTL.Besides,external factors can also participate in sPTL,individually or through the interaction with internal factors.In this article,we summarize recent studies regarding sPTL from our and other groups,and discuss the risk factors and pathogenesis of preterm birth from both external and internal(maternal and fetal)aspects,so as to provide theoretical evidences for the diagnosis,prevention,and treatment of sPTL in the future. 展开更多
关键词 Obstetric labor premature Maternal factor Fetal factor Maternal-fetal crosstalk External factor
原文传递
子宫肌瘤孕妇发生妊娠期肌瘤性疼痛综合征的影响因素及对妊娠结局影响
9
作者 田玉翠 王倩 +1 位作者 王红梅 代荫梅 《山东医药》 CAS 2024年第12期24-27,共4页
目的分析子宫肌瘤孕妇发生妊娠期肌瘤性疼痛综合征的影响因素及对妊娠结局影响。方法395例子宫肌瘤孕妇根据是否出现妊娠期肌瘤性疼痛综合征分为病例组(74例)和对照组(321例),采用单因素分析法及多因素Logistic回归分析法分析子宫肌瘤... 目的分析子宫肌瘤孕妇发生妊娠期肌瘤性疼痛综合征的影响因素及对妊娠结局影响。方法395例子宫肌瘤孕妇根据是否出现妊娠期肌瘤性疼痛综合征分为病例组(74例)和对照组(321例),采用单因素分析法及多因素Logistic回归分析法分析子宫肌瘤孕妇发生妊娠期肌瘤性疼痛综合征的影响因素,另比较两组妊娠结局。结果年龄是发生妊娠期肌瘤性疼痛综合征的影响因素,年龄每减小1岁,妊娠期肌瘤性疼痛综合征的风险增加0.911倍(OR=0.911,95%CI 0.852~0.973,P=0.006)。病例组产后出血占22.38%、先兆早产占23.44%,对照组产后出血占35.69%、先兆早产占8.39%,两组产后出血、先兆早产发生率比较,P均<0.05。结论子宫肌瘤孕妇发生妊娠期肌瘤性疼痛综合征的影响因素是年龄,肌瘤性疼痛综合征增加先兆早产的发生风险。 展开更多
关键词 子宫肌瘤 妊娠期肌瘤相关性疼痛综合征 年龄 先兆早产
下载PDF
卵巢功能不全病因病机及动物模型构建研究进展
10
作者 杨智惠 胡扬 +7 位作者 宗政 孙向明 宋辉 陈鹰翔 徐蓓蕾 张文君 陈鲁宁 李文兰 《中国比较医学杂志》 CAS 北大核心 2024年第3期149-160,共12页
卵巢功能不全(premature ovarian insufficiency,POI)又称“卵巢功能低下”,其发病率高达1%~5%,近年来还呈现不断上升的趋势,已经严重影响女性的身心健康及生活质量。目前,关于POI的发病原因及机制尚不明确,模型构建方法与应用也较混乱... 卵巢功能不全(premature ovarian insufficiency,POI)又称“卵巢功能低下”,其发病率高达1%~5%,近年来还呈现不断上升的趋势,已经严重影响女性的身心健康及生活质量。目前,关于POI的发病原因及机制尚不明确,模型构建方法与应用也较混乱,且绝大多数模型在针对性、稳定性等方面存在一定不足,这也极大的限制了POI的相关研究及其临床诊断和治疗。因此本文对POI的病因病机与POI动物模型的构建进行综述和讨论,以期为POI的病因病机研究及模型的选择和构建提供更多参考。 展开更多
关键词 卵巢功能不全 动物模型 病因病机
下载PDF
早发性卵巢功能不全遗传因素中相关基因改变的研究进展
11
作者 王云迪 吉日嘎拉赛罕巴达日其 王煜 《生殖医学杂志》 CAS 2024年第6期831-836,共6页
早发性卵巢功能不全(POI)是指女性在40岁之前出现月经及激素水平异常等现象。近年来,POI的发病率出现逐年提高的趋势,引起国内外学者的强烈关注。随着全外显子测序、全基因组测序等技术的发展,不同的POI候选基因及致病基因被发现,越来... 早发性卵巢功能不全(POI)是指女性在40岁之前出现月经及激素水平异常等现象。近年来,POI的发病率出现逐年提高的趋势,引起国内外学者的强烈关注。随着全外显子测序、全基因组测序等技术的发展,不同的POI候选基因及致病基因被发现,越来越多的研究证实基因突变参与POI的病理生理过程,大大增加了人们对其遗传学病因的认识。本文从DNA损伤修复和同源重组相关基因、转录因子相关基因及卵巢功能相关基因三个方面综述了POI相关基因改变及其分子机制的最新进展,以期进一步明确其发病机制的多样性,为POI的遗传学筛查和治疗提供新的思路。 展开更多
关键词 早发性卵巢功能不全 基因突变 病因
下载PDF
早产儿支气管肺发育不良发病机制相关因子的研究进展 被引量:1
12
作者 陈蕙卉 李秋平 +1 位作者 边佳昕 孙冬梅 《发育医学电子杂志》 2024年第4期296-301,308,共7页
支气管肺发育不良(bronchopulmonary dysplasia,BPD)是早产儿疾病中最常见的病症之一。BPD患儿不仅会表现出肺功能受损、运动能力差和气道高反应性等,还会表现出长期的并发症。随着高通量测序技术的引入和分子生物学的不断发展,虽然其... 支气管肺发育不良(bronchopulmonary dysplasia,BPD)是早产儿疾病中最常见的病症之一。BPD患儿不仅会表现出肺功能受损、运动能力差和气道高反应性等,还会表现出长期的并发症。随着高通量测序技术的引入和分子生物学的不断发展,虽然其发病机制尚未被完全了解,但患儿的存活率显著提高。加深理解早产儿BPD发生、发展的分子机制,有助于BPD的治疗和护理。本文从肺内皮血管发育、肺部炎症反应和肺泡形成等3个方面综述了BPD相关因子的研究进展,有助于理解BPD的遗传机制。 展开更多
关键词 支气管肺发育不良 早产儿 病因 血管 炎症 肺泡
下载PDF
早发性卵巢功能不全临床研究进展
13
作者 覃继团 任青玲 《华北理工大学学报(医学版)》 2024年第3期248-252,共5页
近年来早发性卵巢功能不全(POI)发病率有逐年上升的趋势,是生殖内分泌领域关注的热点和难点,早期诊断和预防可以减轻患者病痛。本文结合临床和文献资料,综述早发性卵巢功能不全西医病因、治疗,中医病因病机及治疗,为临床诊疗拓展思路,... 近年来早发性卵巢功能不全(POI)发病率有逐年上升的趋势,是生殖内分泌领域关注的热点和难点,早期诊断和预防可以减轻患者病痛。本文结合临床和文献资料,综述早发性卵巢功能不全西医病因、治疗,中医病因病机及治疗,为临床诊疗拓展思路,以期提高POI患者生命质量及健康管理。 展开更多
关键词 早发性卵巢功能不全 西医病因及治疗 中医病因病机及治疗 中西医结合治疗
下载PDF
间苯三酚与阿托西班在先兆早产治疗中的临床效果对比分析
14
作者 叶慧 周愉希 谢晓玲 《药品评价》 CAS 2024年第1期98-101,共4页
目的比较分析间苯三酚与阿托西班治疗先兆早产的临床效果。方法筛选2021年1月至2023年3月上饶市妇幼保健院住院的82例先兆早产孕妇作为研究对象,随机数字表法分A组和B组,各41例。在常规治疗的基础上,A组采用间苯三酚治疗;B组采用阿托西... 目的比较分析间苯三酚与阿托西班治疗先兆早产的临床效果。方法筛选2021年1月至2023年3月上饶市妇幼保健院住院的82例先兆早产孕妇作为研究对象,随机数字表法分A组和B组,各41例。在常规治疗的基础上,A组采用间苯三酚治疗;B组采用阿托西班治疗。比较A、B两组患者用药后的药物起效时间,延长妊娠时间,临床效果,保胎成功率,性激素水平(孕酮、雌三醇),新生儿状态(体质量、头围、身长、Apgar评分)及用药不良反应。结果治疗后,A组患者的药物起效时间较B组相比更快,差异有统计学意义(P<0.05);A组延长妊娠时间较B组更短,差异有统计学意义(P<0.05);A组用药后的临床有效率与B组的临床有效率相比较低,差异有统计学意义(P<0.05);A组保胎成功率与B组相比较低,差异有统计学意义(P<0.05);A组用药后孕酮较B组低,雌三醇较B组高,差异有统计学意义(P<0.05);A组新生儿的体质量、头围、身长、Apgar评分与B组新生儿相比略低,但差异无统计学意义(P>0.05)。比较两组用药后不良反应发生率,A组略低于B组,但差异无统计学意义(P>0.05)。结论在治疗先兆早产时,阿托西班的药物起效时间相较于间苯三酚稍慢,但妊娠延长时间相较于间苯三酚更长,且阿托西班治疗先兆早产后的临床有效率、保胎成功率及改善患者性激素水平的作用与间苯三酚相比更好,故针对治疗先兆早产的患者应优先选用阿托西班。 展开更多
关键词 先兆早产 间苯三酚 阿托西班 临床效果
下载PDF
足月胎膜早破产妇破膜后不同时间引产对产程及母婴结局的影响
15
作者 陈学花 《中国现代药物应用》 2024年第22期31-34,共4页
目的 观察足月胎膜早破(PROM)产妇破膜后不同时间引产对产程及母婴结局的影响。方法 180例足月PROM产妇,均给予缩宫素引产,根据不同引产时间分为A组(破膜后2~12 h内引产,96例)和B组(破膜后>12 h引产,84例);A组和B组根据Bishop评分可... 目的 观察足月胎膜早破(PROM)产妇破膜后不同时间引产对产程及母婴结局的影响。方法 180例足月PROM产妇,均给予缩宫素引产,根据不同引产时间分为A组(破膜后2~12 h内引产,96例)和B组(破膜后>12 h引产,84例);A组和B组根据Bishop评分可进一步细分为A1组(Bishop评分≥6分,59例)、A2组(Bishop评分<6分,37例)和B1组(Bishop评分≥6分,32例)、B2组(Bishop评分<6分,52例)。比较四组产妇的破膜至分娩时间、总产程时间、分娩方式、不良妊娠结局发生情况及新生儿的并发症发生率。结果 破膜至分娩时间:A1组(11.33±3.15)h明显短于A2组的(19.49±6.58)h、B1组的(17.78±4.28)h、B2组的(19.64±6.85)h(P<0.05),A2组、B1组、B2组两两组间比较均无统计学差异(P>0.05)。总产程时间:A1组(6.43±2.11)h、B1组(6.28±1.97)h均明显短于A2组的(9.56±2.43)h、B2组的(9.39±2.20)h(P<0.05),A1组与B1组、A2组与B2组比较均无统计学差异(P>0.05)。剖宫产率:A2组(64.86%)明显高于A1组(27.12%)、B1组(25.00%)、B2组(40.38%)(P<0.05),A1组、B1组、B2组两两组间比较均无统计学差异(P>0.05)。不良妊娠结局发生率:A1组(3.39%)最低,其次是B2组(7.69%),且均明显低于A2组(24.32%)和B1组(25.00%)(P<0.05);A1组与B2组、A2组与B1组比较均无统计学差异(P>0.05)。新生儿的并发症发生率:A1组(5.07%)最低,其次是B2组(7.69%),且均明显低于A2组(29.73%)和B1组(25.00%)(P<0.05);A1组与B2组、A2组与B1组比较均无统计学差异(P>0.05)。结论 对于足月PROM产妇,宫颈成熟度高者在破膜后2~12 h内引产,宫颈成熟度低者在破膜后12 h后引产,更有利于缩短产程和改善母婴结局,为临床探索最优引产时机提供依据。 展开更多
关键词 足月胎膜早破 产程 引产时机 宫颈成熟度 母婴结局
下载PDF
三维超声测量宫颈容积在妇产领域的应用进展
16
作者 甘华 阎萍 《中国医药导报》 CAS 2024年第24期77-81,共5页
近年来,随着超声技术的不断发展,三维超声成像在妇产领域的应用越来越广泛,主要用于胎儿畸形诊断、宫腔病变评估及胎盘体积测量等。三维超声测量宫颈容积通过超声探头在妇女阴道内测量宫颈长度、直径和容积,提供完整和立体的宫颈结构图... 近年来,随着超声技术的不断发展,三维超声成像在妇产领域的应用越来越广泛,主要用于胎儿畸形诊断、宫腔病变评估及胎盘体积测量等。三维超声测量宫颈容积通过超声探头在妇女阴道内测量宫颈长度、直径和容积,提供完整和立体的宫颈结构图像,优于传统二维超声,为临床医师提供关于宫颈功能和疾病的重要信息。三维超声测量宫颈容积可预测早产,但目前不能代替宫颈管长度;宫颈容积可评价孕晚期宫颈成熟度,从而预测引产结局;对宫颈疾病的诊断及预防有潜在临床意义。宫颈容积的测量为临床医师提供新的研究方向及参考价值。由于目前研究较少,今后需更多文献及研究验证三维超声测量宫颈容积在妇产领域的应用价值。 展开更多
关键词 三维超声 宫颈容积 宫颈功能不全 早产 引产 宫颈病变
下载PDF
孕妇宫颈分泌物中胎盘α1-微球蛋白、胎儿纤维连接蛋白水平预测自发性早产价值
17
作者 杨姗姗 孙桂霞 张艳夏 《中国计划生育学杂志》 2024年第7期1653-1657,共5页
目的:探究宫颈分泌物中胎盘α1-微球蛋白(PAMG-1)和胎儿纤维连接蛋白(fFN)水平对自发性早产的预测价值。方法:收集2021年4月-2023年4月本院收治的128例发生自发性早产患者临床资料纳入早产组,同期产前检查并足月分娩的正常孕妇128例临... 目的:探究宫颈分泌物中胎盘α1-微球蛋白(PAMG-1)和胎儿纤维连接蛋白(fFN)水平对自发性早产的预测价值。方法:收集2021年4月-2023年4月本院收治的128例发生自发性早产患者临床资料纳入早产组,同期产前检查并足月分娩的正常孕妇128例临床资料纳入正常组。比较两组临床资料,宫颈分泌物PAMG-1、fFN水平;采用受试者工作曲线(ROC)分析PAMG-1、fFN对孕妇发生自发性早产的预测价值。结果:PAMG-1、fFN对孕妇发生自发性早产的预测准确性分别为68.0%和67.6%、阳性预测值分别为76.1%和73.2%、阴性预测值分别为63.7%和64.2%,2项联合预测的准确性(69.9%)和阳性预测值(79.3%)提高(P<0.05);经ROC曲线分析,PAMG-1、fFN预测孕妇发生自发性早产的曲线下面积分别为0.680和0.679,灵敏度分别为52.3%、55.5%,特异度分别为83.6%、79.7%,2项联合预测的曲线下面积为0.699,灵敏度53.9%、特异度85.9%。结论:PAMG-1、fFN可作为孕妇发生自发生性早产的预测指标,且2项联合可提高预测效能。 展开更多
关键词 自发性早产 宫颈分泌物 胎盘α1-微球蛋白 胎儿纤维连接蛋白 预测价值
下载PDF
早发性卵巢功能不全中医药研究概况
18
作者 范敏 于潇 张丽娟 《中国中医药现代远程教育》 2024年第3期128-131,共4页
早发性卵巢功能不全(POI)是卵巢功能逐渐衰退中的一个阶段。西医对于POI的发病机制尚不明确,治疗采用激素替代(HRT)及辅助生殖技术(IVF-ET),有诸如不良反应多、治疗周期长及费用昂贵等不足。上述不足使中医药在POI的治疗中获得了诸多患... 早发性卵巢功能不全(POI)是卵巢功能逐渐衰退中的一个阶段。西医对于POI的发病机制尚不明确,治疗采用激素替代(HRT)及辅助生殖技术(IVF-ET),有诸如不良反应多、治疗周期长及费用昂贵等不足。上述不足使中医药在POI的治疗中获得了诸多患者的青睐。作者将近年来POI病因病机、中医药治法及中药临床实验研究进行归纳总结,以期为未来治疗该病提供思路和依据。 展开更多
关键词 闭经 早发性卵巢功能不全 病因病机 中医药疗法 综述
下载PDF
妊娠期高血压与不同早产亚型之间的关联性研究
19
作者 王洋 《黑龙江医学》 2024年第19期2319-2322,共4页
目的:探讨妊娠期高血压(HDP)与不同早产亚型之间的关联性。方法:选取2020年1月—2022年12月开封市妇产医院行产前检查的孕妇作为研究对象,通过问卷调查、医院电子病历系统等得到所有孕妇基本资料、孕期情况,对所有孕妇进行随访,直至妊... 目的:探讨妊娠期高血压(HDP)与不同早产亚型之间的关联性。方法:选取2020年1月—2022年12月开封市妇产医院行产前检查的孕妇作为研究对象,通过问卷调查、医院电子病历系统等得到所有孕妇基本资料、孕期情况,对所有孕妇进行随访,直至妊娠终止或分娩,记录妊娠结局的相关信息,并构建孕妇队列。利用log-binomial回归模型分析HDP与不同早产亚型之间的关联性;多个混杂因素利用倾向性评分校正法构建模型计算调整后的关联性。结果:2020—2022年早产率比较,差异有统计学意义(χ^(2)=13.764,P<0.05);在13 662例孕妇中,HDP发生率为3.86%,早产发生率为7.91%。1 080例早产中,18例为医源性早产,占1.67%;1 062例为自发性早产,占98.33%,其中,29.17%为早产临产,69.17%为未足月胎膜早破;两组孕妇自发性早产发生率比较,差异有统计学意义(χ^(2)=90.131,P<0.05);两组孕妇未足月胎膜早破发生率比较,差异有统计学意义(χ^(2)=167.813,P<0.05);调整混杂因素后结果显示,HDP孕妇发生未足月胎膜早破的风险是未发生HDP孕妇的1.96倍(aRR=6.495,95%CI:3.774~11.178),HDP与早产临产无关联性。结论:HDP可增加未足月胎膜早破发生风险,与医源性早产、早产临产可能无关。因此医护人员应加强HDP孕妇胎膜检测,关注炎症、羊水量等指标变化,防治胎膜破裂引发早产。 展开更多
关键词 妊娠期高血压 自发性早产 早产临产 未足月胎膜早破 医源性早产
下载PDF
小剂量米索前列醇联合间苯三酚在足月胎膜早破产妇中的引产效果
20
作者 谢晓 刘娟 +2 位作者 黄秀娟 李忠辉 杨瑜 《中国卫生标准管理》 2024年第23期122-124,129,共4页
目的分析小剂量米索前列醇联合间苯三酚在足月胎膜早破产妇中的引产效果。方法选取2021年10月—2023年10月在东莞市樟木头医院产科就诊的80例足月胎膜早破产妇为研究对象。按引产方式的不同分为研究组(n=41,小剂量米索前列醇联合间苯三... 目的分析小剂量米索前列醇联合间苯三酚在足月胎膜早破产妇中的引产效果。方法选取2021年10月—2023年10月在东莞市樟木头医院产科就诊的80例足月胎膜早破产妇为研究对象。按引产方式的不同分为研究组(n=41,小剂量米索前列醇联合间苯三酚)与对照组(n=39,缩宫素)。比较2组第一产程时间、宫缩乏力发生率、剖宫产率、会阴侧切率及产后2 h出血量。结果研究组第一产程时间为(6.42±2.27)h,短于对照组的(11.36±2.76)h,研究组宫缩乏力发生率为2.44%(1/41),低于对照组的30.77%(12/39),差异有统计学意义(P<0.05)。2组剖宫产率、会阴侧切率及产后2 h出血量比较,差异无统计学意义(P>0.05)。结论足月胎膜早破产妇使用小剂量米索前列醇联合间苯三酚引产可以有效缩短产程时间,提高引产成功率。 展开更多
关键词 小剂量米索前列醇 间苯三酚 足月胎膜早破 引产 第一产程 宫缩乏力
下载PDF
上一页 1 2 25 下一页 到第
使用帮助 返回顶部