Acute ischemic stroke is one of the common discases in Chinese,among which acute ischemic stroke with large vessel occlusion(AIS-LVO)has thc most serious complications and has the risk of death.Studies have shown that...Acute ischemic stroke is one of the common discases in Chinese,among which acute ischemic stroke with large vessel occlusion(AIS-LVO)has thc most serious complications and has the risk of death.Studies have shown that reperfusion is a first-line treatment for the effective rescue of ischemic brain tissue,usually mainly by mechanical|hrombectomy(MT),supplemented by intravenous thrombolysis.However,there are still complications after large blood vessel occlusion and MT.such as blecding and infection at the puncture point,vasospasm,vascular dissection,subarachnoid hemorrhage,hcmonhagic transfomation,reembolization,and massive cerebral infarction,ctc.The high risk factors and corresponding measures of complications after MT by revicwing the rescarch analysis.展开更多
This hybrid transducer type linear ultrasonic motor is a new troe of the lineax ultrasonic motor proposed by the authors. This paper describes its basic structure and operation principle, provides its mechedsm of the ...This hybrid transducer type linear ultrasonic motor is a new troe of the lineax ultrasonic motor proposed by the authors. This paper describes its basic structure and operation principle, provides its mechedsm of the large thrust and large seif lock force when power is cut off. The measured characteristics of the prototype motor are shown, its mtalmum thrust is 11 N and mtalmum output power is 1.4 W, the backward and forward motion performances are roughly coincident展开更多
A quasi-isotropic, quasi-homogeneous turbulence generated by an oscillating-grid, spatially decays according to power law of u ∝ Z-nM , where u is the root mean square （rms） horizontal velocity, Z is the vertical d...A quasi-isotropic, quasi-homogeneous turbulence generated by an oscillating-grid, spatially decays according to power law of u ∝ Z-nM , where u is the root mean square （rms） horizontal velocity, Z is the vertical distance from the grid and nu = 1. However, the findings of Nokes and Yi indicate that as the stroke of oscillation increases, the power law n u= 1 and does not follow the established decay law equation of Hopfinger. This paper investigates the characteristics of the turbulence that are generated using larger strokes S/M = 1.6 and 2 and compares with that obtained using a S/M = 0.8, which is the stroke used when the equation was developed. Measurements of the grid-generated turbulence in a water tank were taken using particle image velocimetry （PIV）. The results showed that the homogeneity occurred at distance beyond 2.5 mesh spacings away from the grid midplane, independent of the stroke and the frequency of oscillation. Within this region, the turbulent kinetic energy distribution was quasi-homogeneous, and the secondary mean flow is negligible. The statistical characteristics of the measured turbulence confirmed that although nu decreases as stroke increases, the grid-turbulence generated at S/M = 1.6 and 2 obeys the universal decay law.展开更多
Patients who received endovascular therapy (EVT) for acute ischemic stroke with large vessel occlusion (AIS-LVO) and large-scaled core infarct volume in the time window were analyzed. Literature data were reviewed. Re...Patients who received endovascular therapy (EVT) for acute ischemic stroke with large vessel occlusion (AIS-LVO) and large-scaled core infarct volume in the time window were analyzed. Literature data were reviewed. Results showed that although EVT is the first choice to AIS-LVO, patients often have poor prognosis. Alberta stroke program early CT score (ASPECTS) based on computerized tomography angiography source image (CTA-SI) can reflect the real cerebral perfusion more truly, and it can assess the size of core infarct more quickly and accurately, thus enabling to judge prognosis.展开更多
Genome-wide association studies have found that rs17612742 increases the risk of large artery atherosclerotic stroke.The rs17612742 was located in the intron region of Endothelin receptor type A(NRA),which was cellula...Genome-wide association studies have found that rs17612742 increases the risk of large artery atherosclerotic stroke.The rs17612742 was located in the intron region of Endothelin receptor type A(NRA),which was cellular and gender-heterogeneous.Functional genomics studies of rs17612742 were carried out through some public databases,and it was found that rs17612742 was located in the chromatin open region and promoted the expression of NRA.Compared with the control group,EDNRA expression increased in middle cerebral artery occlusion exposed rodents.However,age heterogeneity of EDNRA expression under physiological and pathological conditions was not observed.In addition,we also discussed how to conduct further empirical studies to provide evidence that rs17612742 confers the risk of large artery atherosclerotic stroke by increasing the expression of NRA.展开更多
Coiled polymer artificial muscles with both large tensile stroke and giant force generation are needed for practical applications in robotics,soft exosuits,and prosthesis.However,most polymer yarn artificial muscles c...Coiled polymer artificial muscles with both large tensile stroke and giant force generation are needed for practical applications in robotics,soft exosuits,and prosthesis.However,most polymer yarn artificial muscles cannot generate a large force or stress.Here,we report an inexpensive Twisted and Coiled Polymer artificial muscle(TCP)that performs both large isobaric and isometric contractions.This TCP can generate a tensile stroke of 20.1%and a specific work capacity of up to 1.3 kJ kg^(−1) during temperature changes from 20 to 180℃.Moreover,the nylon yarn artificial muscle produced a reversible output stress of 28.4 MPa,which is 100 times larger than human skeletal muscle.A robot arm and a simple gripper were made to demonstrate the isobaric actuation and isometric actuation of our TCP muscle,repectivley.Thus,the polymer artificial muscles with dual-mode actuation show potential applications in the field of robotics,grippers,and exoskeletons and so on.展开更多
基金High Level Talent Program of Hainan Natural Science Foundation(No.821RC680)。
文摘Acute ischemic stroke is one of the common discases in Chinese,among which acute ischemic stroke with large vessel occlusion(AIS-LVO)has thc most serious complications and has the risk of death.Studies have shown that reperfusion is a first-line treatment for the effective rescue of ischemic brain tissue,usually mainly by mechanical|hrombectomy(MT),supplemented by intravenous thrombolysis.However,there are still complications after large blood vessel occlusion and MT.such as blecding and infection at the puncture point,vasospasm,vascular dissection,subarachnoid hemorrhage,hcmonhagic transfomation,reembolization,and massive cerebral infarction,ctc.The high risk factors and corresponding measures of complications after MT by revicwing the rescarch analysis.
文摘This hybrid transducer type linear ultrasonic motor is a new troe of the lineax ultrasonic motor proposed by the authors. This paper describes its basic structure and operation principle, provides its mechedsm of the large thrust and large seif lock force when power is cut off. The measured characteristics of the prototype motor are shown, its mtalmum thrust is 11 N and mtalmum output power is 1.4 W, the backward and forward motion performances are roughly coincident
基金Universiti Kebangsaan Malaysia for the financial support during the author’s postgraduate studies
文摘A quasi-isotropic, quasi-homogeneous turbulence generated by an oscillating-grid, spatially decays according to power law of u ∝ Z-nM , where u is the root mean square （rms） horizontal velocity, Z is the vertical distance from the grid and nu = 1. However, the findings of Nokes and Yi indicate that as the stroke of oscillation increases, the power law n u= 1 and does not follow the established decay law equation of Hopfinger. This paper investigates the characteristics of the turbulence that are generated using larger strokes S/M = 1.6 and 2 and compares with that obtained using a S/M = 0.8, which is the stroke used when the equation was developed. Measurements of the grid-generated turbulence in a water tank were taken using particle image velocimetry （PIV）. The results showed that the homogeneity occurred at distance beyond 2.5 mesh spacings away from the grid midplane, independent of the stroke and the frequency of oscillation. Within this region, the turbulent kinetic energy distribution was quasi-homogeneous, and the secondary mean flow is negligible. The statistical characteristics of the measured turbulence confirmed that although nu decreases as stroke increases, the grid-turbulence generated at S/M = 1.6 and 2 obeys the universal decay law.
文摘Patients who received endovascular therapy (EVT) for acute ischemic stroke with large vessel occlusion (AIS-LVO) and large-scaled core infarct volume in the time window were analyzed. Literature data were reviewed. Results showed that although EVT is the first choice to AIS-LVO, patients often have poor prognosis. Alberta stroke program early CT score (ASPECTS) based on computerized tomography angiography source image (CTA-SI) can reflect the real cerebral perfusion more truly, and it can assess the size of core infarct more quickly and accurately, thus enabling to judge prognosis.
文摘Genome-wide association studies have found that rs17612742 increases the risk of large artery atherosclerotic stroke.The rs17612742 was located in the intron region of Endothelin receptor type A(NRA),which was cellular and gender-heterogeneous.Functional genomics studies of rs17612742 were carried out through some public databases,and it was found that rs17612742 was located in the chromatin open region and promoted the expression of NRA.Compared with the control group,EDNRA expression increased in middle cerebral artery occlusion exposed rodents.However,age heterogeneity of EDNRA expression under physiological and pathological conditions was not observed.In addition,we also discussed how to conduct further empirical studies to provide evidence that rs17612742 confers the risk of large artery atherosclerotic stroke by increasing the expression of NRA.
基金Financial support from the program of the National Natural Science Foundation of China (Grant no.52105057,51905222)Natural Science Foundation of Jiangsu Province (Grant no.BK20200916)+3 种基金China Postdoctoral Science Foundation (no.2021M691307,no.2022T150274)Jiangsu Postdoctoral Research Foundation (no.2021K543C)Key Research Project of Zhejiang LabSenior Talent Foundation of Jiangsu University (Grant no.5501110013)are acknowledged.
文摘Coiled polymer artificial muscles with both large tensile stroke and giant force generation are needed for practical applications in robotics,soft exosuits,and prosthesis.However,most polymer yarn artificial muscles cannot generate a large force or stress.Here,we report an inexpensive Twisted and Coiled Polymer artificial muscle(TCP)that performs both large isobaric and isometric contractions.This TCP can generate a tensile stroke of 20.1%and a specific work capacity of up to 1.3 kJ kg^(−1) during temperature changes from 20 to 180℃.Moreover,the nylon yarn artificial muscle produced a reversible output stress of 28.4 MPa,which is 100 times larger than human skeletal muscle.A robot arm and a simple gripper were made to demonstrate the isobaric actuation and isometric actuation of our TCP muscle,repectivley.Thus,the polymer artificial muscles with dual-mode actuation show potential applications in the field of robotics,grippers,and exoskeletons and so on.
