A new comprehensive empirical large signal model for 4H-SiC MESFETs is proposed. An enhanced drain current model,along with an improved charge conservation capacitance model,is presented by the improvement of the chan...A new comprehensive empirical large signal model for 4H-SiC MESFETs is proposed. An enhanced drain current model,along with an improved charge conservation capacitance model,is presented by the improvement of the channel length modulation and the hyperbolic tangent function coefficient based on the Materka model. The Levenberg-Marquardt method is used to optimize the parameter extraction. A comparison of simulation resuits with experimental data is made,and good agreements of I-V curves, Pout (output power), PAE (power added efficiency) ,and gain at the bias of Vos = 20V, Ips = 80mA as well as the operational frequency of 1.8GHz are obtained.展开更多
This paper reports that a 4H-SiC MESFET (Metal Semiconductor Field Effect Transistor) large signal drain current model based on physical expressions has been developed to be used in CAD tools. The form of drain curr...This paper reports that a 4H-SiC MESFET (Metal Semiconductor Field Effect Transistor) large signal drain current model based on physical expressions has been developed to be used in CAD tools. The form of drain current model is based on semi-empirical MESFET model, and all parameters in this model are determined by physical parameters of 4H-SiC MESFET. The verification of the present model embedded in CAD tools is made, which shows a good agreement with measured data of large signal DC I-V characteristics, PAE (power added efficiency), output power and gain.展开更多
We used data from the Xinjiang Digital Seismic Network and PSD( Power Spectral Density) method to perform noise level assessment for six stations. We calculated the median of the power spectral density to evaluate the...We used data from the Xinjiang Digital Seismic Network and PSD( Power Spectral Density) method to perform noise level assessment for six stations. We calculated the median of the power spectral density to evaluate the noise level of different stations. After the comparison of the power spectral density of different stations and the airgun signal recognition,we found that noise level of stations with recognizable airgun source signals is lower than that of stations without recognizable signals. The largest difference of the power spectral density is 40 d B,and the smallest is 15 d B. Finally,we found that the failure to recognize the signal of airgun sources at some stations is due to the noise level.展开更多
As this is the first time a large volume airgun has been excited in the "Yangtse River Geoscience Project",it is necessary to study the time-frequency characteristic based on the linear stacked seismic data ...As this is the first time a large volume airgun has been excited in the "Yangtse River Geoscience Project",it is necessary to study the time-frequency characteristic based on the linear stacked seismic data from records from portable stations near the fixed fields and seismic stations. Airgun signal propagation distances were detected using stacked seismic data to analyze the environmental impact on signal propagation distance. The results showed that:( 1) the airgun signal produced by bubble pulses,pressure pulses and the surface wave can be received by a portable station near the fixed field;( 2) the dominant frequency of a bubble at 5Hz or so can be received by both near-field stations and far-field stations,pressure pulses rapidly weaken and the dominant frequency bands get narrower as epicentral distance increases;( 3) the longest spread distance of signal is 260 km,the nearest is 180 km,and the signal can travel further in the evening.展开更多
An approximate formula of space charge field of orotron in rectangular coordinate system,when one of the boundaries is infinite, is derived. Using this model the self-consistant large signal interactionof orotron with...An approximate formula of space charge field of orotron in rectangular coordinate system,when one of the boundaries is infinite, is derived. Using this model the self-consistant large signal interactionof orotron with space charge is calculated, and the effect of this charge on the performance of the device isdiscussed.展开更多
To prevent the long-time coherent integration and limited range window stumbling blocks of stretch processing and reduce computational complexity, a novel method called multi-subpulse process of large time-bandwidth p...To prevent the long-time coherent integration and limited range window stumbling blocks of stretch processing and reduce computational complexity, a novel method called multi-subpulse process of large time-bandwidth product linear frequency modulating ( LFM ) signal ( i. e. chirp ) is proposed in this paper. The wideband chirp signal is split up into several compressed subpulses. Then the fast Fourier transform (FFT) is used to reconstruct the high resolution range profile ( HR- RP) in a relative short computation time. For multi-frame, pulse Doppler (PD) process is performed to obtain the two-dimension range-Doppler (R-D) high resolution profile. Simulations and field ex- perimental results show that the proposed method can provide high-quality target profile over a large range window in a short computation time and has the promising potential for long-time coherent in- tegration.展开更多
A Large-signal model for GaAs FET is derived based on its small-signal S parame-ters and DC characteristics. The harmonic balance algorithm is applied to analyze and optimizethe FET fundamental and harmonic oscillator...A Large-signal model for GaAs FET is derived based on its small-signal S parame-ters and DC characteristics. The harmonic balance algorithm is applied to analyze and optimizethe FET fundamental and harmonic oscillators, and the values of steady current are obtained.In the solving process, a simplified CAD approach is used to obtain the parameters of matchingnetwork when the output power is maximum. Finally, a fundamental oscillator and a harmonicoscillator of Q-band are fabricated. The measurements show that the theoretical analysis andexperimental results are in good agreement.展开更多
Large-signal modulation capability, as an important performance indicator, is directly related to the high-speed optical communication technology involved. We experimentally and theoretically investigate the large-sig...Large-signal modulation capability, as an important performance indicator, is directly related to the high-speed optical communication technology involved. We experimentally and theoretically investigate the large-signal modulation characteristics of the simultaneous ground-state (GS) and the excited-state (ES) lasing in InAs/OaAs quantum dot laser diodes. The large-signal modulation capability of total light intensity in the transition regime from OS lasing to two-state lasing is unchanged as the bias-current increases. However, GS and ES large-signal eye diagrams show obvious variations during the transition. Relaxation oscillations and large-signal eye diagrams for OS, ES, and total light intensities are numerically simulated and analyzed in detail by using a rate-equation model. The -ndings show that a complementary relationship between the light intensities for OS and ES lasing exists in both the transition regime and the two-state lasing regime, leading to a much smaller overshooting power and a shorter settling time for the total light intensity. Therefore, the eye diagrams of GS or ES lasing are diffuse whereas those of total light intensity are constant as the bias-current increases in the transition regime.展开更多
Ambient noise tomography(ANT)has been widely used to image crust and upmost mantle structures.ANT assumes that sources of ambient noise are diffuse and evenly distributed in space and the energy of different modes is ...Ambient noise tomography(ANT)has been widely used to image crust and upmost mantle structures.ANT assumes that sources of ambient noise are diffuse and evenly distributed in space and the energy of different modes is equipartitioned.At present,the sources of the primary and the secondary microseisms are well studied,but there are only a few on the studies of long-period ambient noise sources.In this study,we study the effects of large earthquake signals on the recovery of surface waves from seismic ambient noise data recorded by seismic stations from the US permanent networks and Global Seismographic Network(GSN).Our results show that large earthquake signals play an important role on the recovery of long-period surface waves from ambient noise cross-correlation functions.Our results are consistent with previous studies that suggest the contribution of earthquake signals to the recovery of surface waves from cross-correlations of ambient noise is dominant at periods larger than 20–40 s.展开更多
Recently, various control methods represented by proportional-integral-derivative (PID) control are used for robotic control. To cope with the requirements for high response and precision, advanced feedforward contr...Recently, various control methods represented by proportional-integral-derivative (PID) control are used for robotic control. To cope with the requirements for high response and precision, advanced feedforward controllers such as gravity compensator, Coriolis/centrifugal force compensator and friction compensators have been built in the controller. Generally, it causes heavy computational load when calculating the compensating value within a short sampling period. In this paper, integrated recurrent neural networks are applied as a feedforward controller for PUMA560 manipulator. The feedforward controller works instead of gravity and Coriolis/centrifugal force compensators. In the learning process of the neural network by using back propagation algorithm, the learning coefficient and gain of sigmoid function are tuned intuitively and empirically according to teaching signals. The tuning is complicated because it is being conducted by trial and error. Especially, when the scale of teaching signal is large, the problem becomes crucial. To cope with the problem which concerns the learning performance, a simple and adaptive learning technique for large scale teaching signals is proposed. The learning techniques and control effectiveness are evaluated through simulations using the dynamic model of PUMA560 manipulator.展开更多
Non-vanishing electromagnetic properties of neutrinos have been predicted by many theories beyond the Standard Model, and an enhanced neutrino magnetic moment can have profound implications for fundamental physics. Th...Non-vanishing electromagnetic properties of neutrinos have been predicted by many theories beyond the Standard Model, and an enhanced neutrino magnetic moment can have profound implications for fundamental physics. The XENON1T experiment recently detected an excess of electron recoil events in the 1–7 keV energy range, which can be compatible with solar neutrino magnetic moment interaction at a most probable value of μ_(v) = 2.1 × 10^(-11)μ_(B).However, tritium backgrounds or solar axion interaction in this energy window are equally plausible causes.Upcoming multi-tonne noble liquid detectors will test these scenarios more in depth, but will continue to face similar ambiguity. We report a unique capability of future large liquid scintillator detectors to help resolve the potential neutrino magnetic moment scenario. With O(100) kton·year exposure of liquid scintillator to solar neutrinos, a sensitivity of μ_(v) < 10^(-11)μ_(B) can be reached at an energy threshold greater than 40 keV, where no tritium or solar axion events but only neutrino magnetic moment signal is still present.展开更多
Backgroud and Objective Tumor metastasis is not only the malignant marker and characteristics of lung cancer, but also the main cause of failure to cure and lose their life of the
Backgroud and Objective At present, lung cancer has become the most frenquent malignant tumor in China and in the world which its mortality and morbidity is increasing fastest.
Backgroud and Objective Tumor metastasis is not only the malignant marker and characteristics of lung cancer, but also the key cause of failure to cure and lose their life of the patients
Tram systems with the advantages of reliable operation,comfort,low emissions and moderate capacity have been quite popular in recent years in China.However,there are still problems with tram signal control(e.g.evaluat...Tram systems with the advantages of reliable operation,comfort,low emissions and moderate capacity have been quite popular in recent years in China.However,there are still problems with tram signal control(e.g.evaluation model,signal control strategies).In-depth analysis on existing operational issues of trams,calculation of two evaluation indexes,as well as a flexible model-free tram signal priority method were developed to deal with tram problems.Empirical research in Songjiang District,Shanghai shows that:(1)The function of the green extension strategy is limited with c.a.10%tram priority improvement,while the optimal one can reach to 85%higher on average.(2)A scheme with a benefit for trams and with no negative impact,and even benefits,for general traffic can be realized.(3)The optimal solution is beneficial for intersections with a maximum c.a.70%amelioration with delay decreasing from 132.7 s/vehicle to 40.89 s/vehicle,or from 104.77 s/capita to 22.31 s/capita.This paper has great significance for the signal optimization and safety of tram systems,even the development of a comprehensive transportation system for a city.展开更多
A solution scheme is proposed in this paper for an existing RTDHT system to simulate large-scale finite element (FE) numerical substructures. The analysis of the FE numerical substructure is split into response anal...A solution scheme is proposed in this paper for an existing RTDHT system to simulate large-scale finite element (FE) numerical substructures. The analysis of the FE numerical substructure is split into response analysis and signal generation tasks, and executed in two different target computers in real-time. One target computer implements the response analysis task, wherein a large time-step is used to solve the FE substructure, and another target computer implements the signal generation task, wherein an interpolation program is used to generate control signals in a small time-step to meet the input demand of the controller. By using this strategy, the scale of the FE numerical substructure simulation may be increased significantly. The proposed scheme is initially verified by two FE numerical substructure models with 98 and 1240 degrees of freedom (DOFs). Thereafter, RTDHTs of a single frame-foundation structure are implemented where the foundation, considered as the numerical substructure, is simulated by the FE model with 1240 DOFs. Good agreements between the results of the RTDHT and those from the FE analysis in ABAQUS are obtained.展开更多
Optical buffers are critical for optical signal processing in future optical packet-switched networks. In this paper, a theoretical study as well as an experimental demonstration on a new optical buffer with large dyn...Optical buffers are critical for optical signal processing in future optical packet-switched networks. In this paper, a theoretical study as well as an experimental demonstration on a new optical buffer with large dynamical delay time is carried out based on cascaded double loop optical buffers (I:)LOBs). It is found that pulse distortion can be restrained by a negative optical control mode when the optical packet is in the loop. Noise analysis indicates that it is feasible to realise a large variable delay range by cascaded DLOBs. These conclusions are validated by the experiment system with 4-stage cascaded DLOBs. Both the theoretical simulations and the experimental results indicate that a large delay range of 1-9999 times the basic delay unit and a fine granularity of 25 ns can be achieved by the cascaded DLOBs. The performance of the cascaded DLOBs is suitable for the all optical networks.展开更多
BACKGROUND Colorectal cancer(CRC)is the third most common cancer worldwide,with the fourth highest mortality among all cancers.Reportedly,in addition to adenomas,serrated polyps,which account for 15%-30%of CRCs,can al...BACKGROUND Colorectal cancer(CRC)is the third most common cancer worldwide,with the fourth highest mortality among all cancers.Reportedly,in addition to adenomas,serrated polyps,which account for 15%-30%of CRCs,can also develop into CRCs through the serrated pathway.Sessile serrated adenomas/polyps(SSAs/Ps),a type of serrated polyps,are easily misdiagnosed during endoscopy.AIM To observe the difference in the Wnt signaling pathway expression in SSAs/Ps patients with different syndrome types.METHODS From January 2021 to December 2021,patients with SSAs/Ps were recruited from the Endoscopy Room of Shanghai Traditional Chinese Medicine-Integrated Hospital,affiliated with Shanghai University of Traditional Chinese Medicine.Thirty cases each of large intestine damp-heat(Da-Chang-Shi-Re,DCSR)syndrome and spleen-stomach weakness(Pi-Wei-Xu-Ruo)syndrome were reported.Baseline comparison of the general data,typical tongue coating,colonoscopy findings,and hematoxylin and eosin findings was performed in each group.The expression of the Wnt pathway-related proteins,namelyβ-catenin,adenomatous polyposis coli,and mutated in colorectal cancer,were analyzed using immunohistochemistry.RESULTS Significant differences were observed with respect to the SSAs/Ps size between the two groups of patients with different syndrome types(P=0.001).The other aspects did not differ between the two groups.The Wnt signaling pathway was activated in patients with SSAs/Ps belonging to both groups,which was manifested asβ-catenin protein translocation into the nucleus.However,SSAs/Ps patients with DCSR syndrome had more nucleation,higherβ-catenin expression,and negative regulatory factor(adenomatous polyposis coli and mutated in colorectal cancer)expression(P<0.0001)than SSA/P patients with Pi-Wei-Xu-Ruo syndrome.In addition,the SSA/P size was linearly correlated with the related protein expression.CONCLUSION Patients with DCSR syndrome had a more obvious Wnt signaling pathway activation and a higher risk of carcinogenesis.A high-quality colonoscopic diagnosis was essential.The thorough assessment of clinical diseases can be improved by combining the diseases of Western medicine with the syndromes of traditional Chinese medicine.展开更多
文摘A new comprehensive empirical large signal model for 4H-SiC MESFETs is proposed. An enhanced drain current model,along with an improved charge conservation capacitance model,is presented by the improvement of the channel length modulation and the hyperbolic tangent function coefficient based on the Materka model. The Levenberg-Marquardt method is used to optimize the parameter extraction. A comparison of simulation resuits with experimental data is made,and good agreements of I-V curves, Pout (output power), PAE (power added efficiency) ,and gain at the bias of Vos = 20V, Ips = 80mA as well as the operational frequency of 1.8GHz are obtained.
文摘This paper reports that a 4H-SiC MESFET (Metal Semiconductor Field Effect Transistor) large signal drain current model based on physical expressions has been developed to be used in CAD tools. The form of drain current model is based on semi-empirical MESFET model, and all parameters in this model are determined by physical parameters of 4H-SiC MESFET. The verification of the present model embedded in CAD tools is made, which shows a good agreement with measured data of large signal DC I-V characteristics, PAE (power added efficiency), output power and gain.
基金jointly funded by the Special Fund of Earthquake Industry(201508008)National Natural Science Foundation of China(41474051)Scientific Institution Innovation and Development Fund of Xinjiang Uygur Autonomous Region(201316)
文摘We used data from the Xinjiang Digital Seismic Network and PSD( Power Spectral Density) method to perform noise level assessment for six stations. We calculated the median of the power spectral density to evaluate the noise level of different stations. After the comparison of the power spectral density of different stations and the airgun signal recognition,we found that noise level of stations with recognizable airgun source signals is lower than that of stations without recognizable signals. The largest difference of the power spectral density is 40 d B,and the smallest is 15 d B. Finally,we found that the failure to recognize the signal of airgun sources at some stations is due to the noise level.
基金jointly sponsored by the Special Fund for Earthquake Scientific Research in the Public Welfare of China Earthquake Administration(2015419015)the National Natural Science Foundation of China(41474071)
文摘As this is the first time a large volume airgun has been excited in the "Yangtse River Geoscience Project",it is necessary to study the time-frequency characteristic based on the linear stacked seismic data from records from portable stations near the fixed fields and seismic stations. Airgun signal propagation distances were detected using stacked seismic data to analyze the environmental impact on signal propagation distance. The results showed that:( 1) the airgun signal produced by bubble pulses,pressure pulses and the surface wave can be received by a portable station near the fixed field;( 2) the dominant frequency of a bubble at 5Hz or so can be received by both near-field stations and far-field stations,pressure pulses rapidly weaken and the dominant frequency bands get narrower as epicentral distance increases;( 3) the longest spread distance of signal is 260 km,the nearest is 180 km,and the signal can travel further in the evening.
基金This project is supported by the Natural Science Fundation of China
文摘An approximate formula of space charge field of orotron in rectangular coordinate system,when one of the boundaries is infinite, is derived. Using this model the self-consistant large signal interactionof orotron with space charge is calculated, and the effect of this charge on the performance of the device isdiscussed.
基金Supported by the National Natural Science Foundation of China(61301189)
文摘To prevent the long-time coherent integration and limited range window stumbling blocks of stretch processing and reduce computational complexity, a novel method called multi-subpulse process of large time-bandwidth product linear frequency modulating ( LFM ) signal ( i. e. chirp ) is proposed in this paper. The wideband chirp signal is split up into several compressed subpulses. Then the fast Fourier transform (FFT) is used to reconstruct the high resolution range profile ( HR- RP) in a relative short computation time. For multi-frame, pulse Doppler (PD) process is performed to obtain the two-dimension range-Doppler (R-D) high resolution profile. Simulations and field ex- perimental results show that the proposed method can provide high-quality target profile over a large range window in a short computation time and has the promising potential for long-time coherent in- tegration.
文摘A Large-signal model for GaAs FET is derived based on its small-signal S parame-ters and DC characteristics. The harmonic balance algorithm is applied to analyze and optimizethe FET fundamental and harmonic oscillators, and the values of steady current are obtained.In the solving process, a simplified CAD approach is used to obtain the parameters of matchingnetwork when the output power is maximum. Finally, a fundamental oscillator and a harmonicoscillator of Q-band are fabricated. The measurements show that the theoretical analysis andexperimental results are in good agreement.
基金Supported by the National Key Research and Development Program of China under Grant No 2016YFB0402302the National Natural Science Foundation of China under Grant No 91433206
文摘Large-signal modulation capability, as an important performance indicator, is directly related to the high-speed optical communication technology involved. We experimentally and theoretically investigate the large-signal modulation characteristics of the simultaneous ground-state (GS) and the excited-state (ES) lasing in InAs/OaAs quantum dot laser diodes. The large-signal modulation capability of total light intensity in the transition regime from OS lasing to two-state lasing is unchanged as the bias-current increases. However, GS and ES large-signal eye diagrams show obvious variations during the transition. Relaxation oscillations and large-signal eye diagrams for OS, ES, and total light intensities are numerically simulated and analyzed in detail by using a rate-equation model. The -ndings show that a complementary relationship between the light intensities for OS and ES lasing exists in both the transition regime and the two-state lasing regime, leading to a much smaller overshooting power and a shorter settling time for the total light intensity. Therefore, the eye diagrams of GS or ES lasing are diffuse whereas those of total light intensity are constant as the bias-current increases in the transition regime.
基金supported by the National Natural Science Foundation of China(No.41874058).
文摘Ambient noise tomography(ANT)has been widely used to image crust and upmost mantle structures.ANT assumes that sources of ambient noise are diffuse and evenly distributed in space and the energy of different modes is equipartitioned.At present,the sources of the primary and the secondary microseisms are well studied,but there are only a few on the studies of long-period ambient noise sources.In this study,we study the effects of large earthquake signals on the recovery of surface waves from seismic ambient noise data recorded by seismic stations from the US permanent networks and Global Seismographic Network(GSN).Our results show that large earthquake signals play an important role on the recovery of long-period surface waves from ambient noise cross-correlation functions.Our results are consistent with previous studies that suggest the contribution of earthquake signals to the recovery of surface waves from cross-correlations of ambient noise is dominant at periods larger than 20–40 s.
基金supported by Grant-in-Aid for Scientific Research(C) (No. 20560248) of Japan
文摘Recently, various control methods represented by proportional-integral-derivative (PID) control are used for robotic control. To cope with the requirements for high response and precision, advanced feedforward controllers such as gravity compensator, Coriolis/centrifugal force compensator and friction compensators have been built in the controller. Generally, it causes heavy computational load when calculating the compensating value within a short sampling period. In this paper, integrated recurrent neural networks are applied as a feedforward controller for PUMA560 manipulator. The feedforward controller works instead of gravity and Coriolis/centrifugal force compensators. In the learning process of the neural network by using back propagation algorithm, the learning coefficient and gain of sigmoid function are tuned intuitively and empirically according to teaching signals. The tuning is complicated because it is being conducted by trial and error. Especially, when the scale of teaching signal is large, the problem becomes crucial. To cope with the problem which concerns the learning performance, a simple and adaptive learning technique for large scale teaching signals is proposed. The learning techniques and control effectiveness are evaluated through simulations using the dynamic model of PUMA560 manipulator.
基金Supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant No. XDA10010800)the Double First Class Start-up Fund (WF220442603) provided by Shanghai Jiao Tong Universitysupport from the CAS Center for Excellence in Particle Physics (CCEPP)。
文摘Non-vanishing electromagnetic properties of neutrinos have been predicted by many theories beyond the Standard Model, and an enhanced neutrino magnetic moment can have profound implications for fundamental physics. The XENON1T experiment recently detected an excess of electron recoil events in the 1–7 keV energy range, which can be compatible with solar neutrino magnetic moment interaction at a most probable value of μ_(v) = 2.1 × 10^(-11)μ_(B).However, tritium backgrounds or solar axion interaction in this energy window are equally plausible causes.Upcoming multi-tonne noble liquid detectors will test these scenarios more in depth, but will continue to face similar ambiguity. We report a unique capability of future large liquid scintillator detectors to help resolve the potential neutrino magnetic moment scenario. With O(100) kton·year exposure of liquid scintillator to solar neutrinos, a sensitivity of μ_(v) < 10^(-11)μ_(B) can be reached at an energy threshold greater than 40 keV, where no tritium or solar axion events but only neutrino magnetic moment signal is still present.
基金supported by grants from National Natural Sciences Foundation of China (to Qinghua ZHOU, No.3007033 )
文摘Backgroud and Objective Tumor metastasis is not only the malignant marker and characteristics of lung cancer, but also the main cause of failure to cure and lose their life of the
基金supported by the Key Project of National Natural Sciences Fundation of China (to Qinghua ZHOU) (No. 30430300)grant from the National Natural Science Foundation of China. ( to Qinghua ZHOU)(No.3007033 )
文摘Backgroud and Objective At present, lung cancer has become the most frenquent malignant tumor in China and in the world which its mortality and morbidity is increasing fastest.
基金supported by grants from the Key Project of National Natural Science Foundation of China (to Qinghua ZHOU) (No.30430300)National Natural Science Foundation of China (to Qinghua ZHOU) (No.30070333)
文摘Backgroud and Objective Tumor metastasis is not only the malignant marker and characteristics of lung cancer, but also the key cause of failure to cure and lose their life of the patients
基金supported by the National Nature Science Foundation of China(Grant No.51178343)。
文摘Tram systems with the advantages of reliable operation,comfort,low emissions and moderate capacity have been quite popular in recent years in China.However,there are still problems with tram signal control(e.g.evaluation model,signal control strategies).In-depth analysis on existing operational issues of trams,calculation of two evaluation indexes,as well as a flexible model-free tram signal priority method were developed to deal with tram problems.Empirical research in Songjiang District,Shanghai shows that:(1)The function of the green extension strategy is limited with c.a.10%tram priority improvement,while the optimal one can reach to 85%higher on average.(2)A scheme with a benefit for trams and with no negative impact,and even benefits,for general traffic can be realized.(3)The optimal solution is beneficial for intersections with a maximum c.a.70%amelioration with delay decreasing from 132.7 s/vehicle to 40.89 s/vehicle,or from 104.77 s/capita to 22.31 s/capita.This paper has great significance for the signal optimization and safety of tram systems,even the development of a comprehensive transportation system for a city.
基金National Natural Science Foundation under Grant Nos.51179093,91215301 and 41274106the Specialized Research Fund for the Doctoral Program of Higher Education under Grant No.20130002110032Tsinghua University Initiative Scientific Research Program under Grant No.20131089285
文摘A solution scheme is proposed in this paper for an existing RTDHT system to simulate large-scale finite element (FE) numerical substructures. The analysis of the FE numerical substructure is split into response analysis and signal generation tasks, and executed in two different target computers in real-time. One target computer implements the response analysis task, wherein a large time-step is used to solve the FE substructure, and another target computer implements the signal generation task, wherein an interpolation program is used to generate control signals in a small time-step to meet the input demand of the controller. By using this strategy, the scale of the FE numerical substructure simulation may be increased significantly. The proposed scheme is initially verified by two FE numerical substructure models with 98 and 1240 degrees of freedom (DOFs). Thereafter, RTDHTs of a single frame-foundation structure are implemented where the foundation, considered as the numerical substructure, is simulated by the FE model with 1240 DOFs. Good agreements between the results of the RTDHT and those from the FE analysis in ABAQUS are obtained.
基金supported by the State Key Development Program for Basic Research of China (Grant No.2010CB328300)the National Natural Science Foundation of China (Grant Nos.60677004 and 60702049)+1 种基金the Program for the New Century Excellent Talents in University of China (Grant No.NECT-07-0111)the Innovation Plan for Youth of Beijing University of Posts and Telecommunications
文摘Optical buffers are critical for optical signal processing in future optical packet-switched networks. In this paper, a theoretical study as well as an experimental demonstration on a new optical buffer with large dynamical delay time is carried out based on cascaded double loop optical buffers (I:)LOBs). It is found that pulse distortion can be restrained by a negative optical control mode when the optical packet is in the loop. Noise analysis indicates that it is feasible to realise a large variable delay range by cascaded DLOBs. These conclusions are validated by the experiment system with 4-stage cascaded DLOBs. Both the theoretical simulations and the experimental results indicate that a large delay range of 1-9999 times the basic delay unit and a fine granularity of 25 ns can be achieved by the cascaded DLOBs. The performance of the cascaded DLOBs is suitable for the all optical networks.
基金Supported by the National Natural Science Foundation of China,No.81873253the Shanghai Natural Science Foundation,No.22ZR1458800+1 种基金the Hongkou District Health Committee,No.HKZK2020A01the Xinglin Scholar Program of Shanghai University of Traditional Chinese Medicine,No.[2020]23.
文摘BACKGROUND Colorectal cancer(CRC)is the third most common cancer worldwide,with the fourth highest mortality among all cancers.Reportedly,in addition to adenomas,serrated polyps,which account for 15%-30%of CRCs,can also develop into CRCs through the serrated pathway.Sessile serrated adenomas/polyps(SSAs/Ps),a type of serrated polyps,are easily misdiagnosed during endoscopy.AIM To observe the difference in the Wnt signaling pathway expression in SSAs/Ps patients with different syndrome types.METHODS From January 2021 to December 2021,patients with SSAs/Ps were recruited from the Endoscopy Room of Shanghai Traditional Chinese Medicine-Integrated Hospital,affiliated with Shanghai University of Traditional Chinese Medicine.Thirty cases each of large intestine damp-heat(Da-Chang-Shi-Re,DCSR)syndrome and spleen-stomach weakness(Pi-Wei-Xu-Ruo)syndrome were reported.Baseline comparison of the general data,typical tongue coating,colonoscopy findings,and hematoxylin and eosin findings was performed in each group.The expression of the Wnt pathway-related proteins,namelyβ-catenin,adenomatous polyposis coli,and mutated in colorectal cancer,were analyzed using immunohistochemistry.RESULTS Significant differences were observed with respect to the SSAs/Ps size between the two groups of patients with different syndrome types(P=0.001).The other aspects did not differ between the two groups.The Wnt signaling pathway was activated in patients with SSAs/Ps belonging to both groups,which was manifested asβ-catenin protein translocation into the nucleus.However,SSAs/Ps patients with DCSR syndrome had more nucleation,higherβ-catenin expression,and negative regulatory factor(adenomatous polyposis coli and mutated in colorectal cancer)expression(P<0.0001)than SSA/P patients with Pi-Wei-Xu-Ruo syndrome.In addition,the SSA/P size was linearly correlated with the related protein expression.CONCLUSION Patients with DCSR syndrome had a more obvious Wnt signaling pathway activation and a higher risk of carcinogenesis.A high-quality colonoscopic diagnosis was essential.The thorough assessment of clinical diseases can be improved by combining the diseases of Western medicine with the syndromes of traditional Chinese medicine.