Study on the Production Benefit of Large-scale Tobacco Growers

The tobacco growers with the growing area of greater than or equal to 100 mu,have become an important subject of tobacco production in Weng'an County of Guizhou Province. Regulating and developing the production and business activities of large-scale tobacco growers, plays an important role in stabilizing tobacco production,reducing costs and increasing efficiency in Weng'an County. Through the field survey of large-scale growers' production activities,this article analyzes the input and output levels,and explores the key factors influencing benefit, in order to provide a basis for further regulating the tobacco growing practices and improving the flue-cured tobacco production benefit.

Series Design of Large-Scale NC Machine Tool

Product system design is a mature concept in western developed countries. It has been applied in war industry during the last century. However,up until now,functional combination is still the main method for product system de-sign in China. Therefore,in terms of a concept of product generation and product interaction we are in a weak position compared with the requirements of global markets. Today,the idea of serial product design has attracted much attention in the design field and the definition of product generation as well as its parameters has already become the standard in serial product designs. Although the design of a large-scale NC machine tool is complicated,it can be further optimized by the precise exercise of object design by placing the concept of platform establishment firmly into serial product de-sign. The essence of a serial product design has been demonstrated by the design process of a large-scale NC machine tool.

As Could We Assure Safety in Large-Scale Manufacturing of Nanoparticles for the Biomedical Use

Nanoparticles provide great advantages but also great risks. Risks associating with nanoparticles are the problem of all technologies, but they increase in many times in nanotechnologies. Adequate methods of outgoing production inspection are necessary to solve the problem of risks, and the inspection must be based on the safety standard. Existing safety standard results from a principle of “maximum permissible concentrations or MPC”. This principle is not applicable to nanoparticles, but a safety standard reflecting risks inherent in nanoparticles doesn’t exist. Essence of the risks is illustrated by the example from pharmacology, since its safety assurance is conceptually based on MPC and it has already come against this problem. Possible formula of safety standard for nanoparticles is reflected in many publications, but conventional inspection methods cannot provide its realization, and this gap is an obstacle to assumption of similar formulas. Therefore the development of nanoparticle industry as a whole (also development of the pharmacology in particular) is impossible without the creation of an adequate inspection method. There are suggested new inspection methods founded on the new physical principle and satisfying to the adequate safety standard for nanoparticles. These methods demonstrate that creation of the adequate safety standard and the outgoing production inspection in a large-scale manufacturing of nanoparticles are the solvable problems. However there is a great distance between the physical principle and its hardware realization, and a transition from the principle to the hardware demands great intellectual and material costs. Therefore it is desirable to call attention of the public at large to the necessity of urgent expansions of investigations associated with outgoing inspections in nanoparticles technologies. It is necessary also to attract attention, first, of representatives of state structures controlling approvals of the adequate safety standard to this problem, since it is impossible to compel producers providing the safety without the similar standard, and, second, of leaders of pharmacological industry, since their industry already entered into the nanotechnology era, and they have taken an interest in a forthcoming development of inspection methods.

Geothermal extraction performance in fractured granite from Gonghe Basin,Qinghai province,China:Long-term injection and production experiment

The efficient exploitation of geothermal energy through enhanced geothermal systems(EGS)has been a relevant topic for hot dry rock(HDR)geothermal resources.When cryogenic fluid is injected into a thermal reservoir,improving heat exchange efficiency is key to achieving the optimal exploitation of HDR.In this paper,granite outcrops from Gonghe Basin were used as the testing sample.The natural fractures in the granite samples were relatively well developed.To simulate long-term injection and production from multi-wells in situ,physical ex-periments were performed in a newly-developed,in-house large-scale true triaxial experimental system.Geothermal extraction performance of an HDR was simulated for long-term injection and production operations.Simultaneously,the mode of one-injection and multiple-production wells was represented.In the paper,the ef-fects of the production-injection well spacing,the number of production wells and the injection rate on the production temperature and flow rate are discussed.The results show that,during long-term injection and pro-duction,there are two stages of production temperature variation,namely stabilization and attenuation.When the number of the production wells is increased,the heat extraction efficiency is accelerated.Moreover,competitive diversion of fluid among fractures occurred due to different conductivities.Furthermore,under different pro-duction modes,the production flow rate contributed differently to the heat extraction.Finally,the effect of the production-injection wells spacing on the heat exchange performance was analyzed;this is mainly reflected in the change of the effective heat exchange area between the rock and the injected fluid.The results emphasize the importance of designing an appropriate production mode and optimizing the injection-production parameters to ensure efficient HDR exploitation.

Mercury flows in large-scale gold production and implications for Hg pollution control

Large-scale gold production（LSGP） is one of the five convention-related atmospheric mercury（Hg） emission sources in the Minamata Convention on Mercury. However, field experiments on Hg flows of the whole process of LSGP are limited. To identify the atmospheric Hg emission points and understand Hg emission characteristics of LSGP, Hg flows in two gold smelters were studied. Overall atmospheric Hg emissions accounted for 10%–17% of total Hg outputs and the Hg emission factors for all processes were 7.6–9.6 kg/ton. There were three dominant atmospheric Hg emission points in the studied gold smelters, including the exhaust gas of the roasting process, exhaust gas from the environmental fog collection stack and exhaust gas from the converter of the refining process. Atmospheric Hg emissions from the roasting process only accounted for 16%–29% of total emissions and the rest were emitted from the refining process. The overall Hg speciation profile（gaseous elemental Hg/gaseous oxidized Hg/particulate-bound Hg） for LSGP was 34.1/57.1/8.8. The dominant Hg output byproducts included waste acid, sulfuric acid and cyanide leaching residue. Total Hg outputs from these three byproducts were 80% in smelter A and 84% in smelter B. Our study indicated that previous atmospheric Hg emissions from large-scale gold production might have been overestimated.Hg emission control in LSGP is not especially urgent in China compared to other significant emission sources（e.g., cement plants）. Instead, LSGP is a potential Hg release source due to the high Hg output proportions to acid and sludge.

2D CoOOH Sheet-Encapsulated Ni2P into Tubular Arrays Realizing 1000 mA cm^-2-Level-Current-Density Hydrogen Evolution Over 100 h in Neutral Water

Water electrolysis at high current density(1000 mA cm-2 level)with excellent durability especially in neutral electrolyte is the pivotal issue for green hydrogen from experiment to industrialization.In addition to the high intrinsic activity determined by the electronic structure,electrocatalysts are also required to be capable of fast mass transfer(electrolyte recharge and bubble overflow)and high mechanical stability.Herein,the 2D CoOOH sheet-encapsulated Ni2P into tubular arrays electrocatalytic system was proposed and realized 1000 mA cm-2-levelcurrent-density hydrogen evolution over 100 h in neutral water.In designed catalysts,2D stack structure as an adaptive material can buffer the shock of electrolyte convection,hydrogen bubble rupture,and evolution through the release of stress,which insure the long cycle stability.Meanwhile,the rich porosity between stacked units contributed the good infiltration of electrolyte and slippage of hydrogen bubbles,guaranteeing electrolyte fast recharge and bubble evolution at the high-current catalysis.Beyond that,the electron structure modulation induced by interfacial charge transfer is also beneficial to enhance the intrinsic activity.Profoundly,the multiscale coordinated regulation will provide a guide to design high-efficiency industrial electrocatalysts.

Preliminary Discussion on the Construction and Development of Modern Refinery in China

Sustainable development of refinery is an important problem that refining industry faces in the21st Century. The situation and challenges in front of refining industry are analyzed and illustrated byexamples in this paper. It is also recognized that large-scale, clean, light-oriented and integrated refinery isthe mode of development in future, and also an important measure for the sustainable development ofpetroleum resource.

Next-generation synthetic biology approaches for the accelerated discovery of microbial natural products

Microbial natural products(NPs)and their derivates have been widely used in health care and agriculture during the past few decades.Although large-scale bacterial or fungal(meta)genomic mining has revealed the tremendous biosynthetic potentials to produce novel small molecules,there remains a lack of universal approaches to link NP biosynthetic gene clusters(BGCs)to their associated products at a large scale and speed.In the last ten years,a series of emerging technologies have been established alongside the developments in synthetic biology to engineer cryptic metabolite BGCs and edit host genomes.Diverse computational tools,such as antiSMASH and PRISM,have also been simultaneously developed to rapidly identify BGCs and predict the chemical structures of their products.This review discusses the recent developments and trends pertaining to the accelerated discovery of microbial NPs driven by a wide variety of next-generation synthetic biology approaches,with an emphasis on the in situ activation of silent BGCs at scale,the direct cloning or refactoring of BGCs of interest for heterologous expression,and the synthetic-bioinformatic natural products(syn-BNP)approach for the guided rapid access of bioactive non-ribosomal peptides.

Strategic Height of Standards Arena

The article explains the meaning and its extreme importance of the strategic heights for the standardization field, deliberates over the challenges for traditional standardization, and proposes the urgency of the transformation towards modernized standardization. Affirming the limited role of existing methods like modularization and comprehensive standardization, the author insists on the necessity of accelerating the development of modernized standardization to meet the increasing demand of modern society towards standardization. It is a historical mission for current standardizers to focus on theories, methodologies and innovations in the modern standardization arena.

一种基于“最优捕集窗口”设计的全球化空气取水系统

Atmospheric water harvesting(AWH)is a promising solution to the water shortage problem.Current sorption-based AWH(SAWH)systems seldom obtain both wide climatic adaptability and high energy efficiency due to the lack of thermodynamic optimization.To achieve the ideal harvesting circulation in SAWH systems,the“optimal harvesting window”(OHW)design based on thermodynamic analysis was first proposed and validated by our prototype.The“OHW”theory indicates the water production rate and energy efficiency could be improved by properly reducing the adsorption temperature.As the humidity increases,the optimal adsorption temperature should be closer to the dew point of the environment.Experimental results revealed that,loaded with 3 kg widely adopted silica gel,the daily water production could reach 5.76-17.64 L/d with ultrahigh energy efficiency of 0.46-1.5 L/kWh.This prototype could also achieve optimal performance in wide climatic conditions in terms of 13-35℃and 18%-72%RH.Lastly,the performance of photovoltaic(PV)-driven SAWH was evaluated.Results showed that a 1 m^(2)PV panel could generate 0.66-2 L water per day in Shanghai throughout the year,the highest in opening literature.Notably,this work introduces a promising concept that can help achieve large-scale,ultra-fast,energyefficient AWH worldwide.

Wet-milling synthesis of immobilized Pt/Ir nanoclusters as promising heterogeneous catalysts

Being a typical state of the art heterogeneous catalyst,supported noble metal catalyst often demonstrates enhanced catalytic properties.However,a facile synthetic method for realizing large-scale and low-cost supported noble metal catalyst is strictly indispensable.To this end,by making use of the strong metal-support interaction(SMSI)and mechanochemical reaction,we introduce an efficient synthetic route to obtain ultrafine Pt and Ir nanoclusters immobilized on diverse substrates by wet chemical milling.We further demonstrate the scaling-up effect of our approach by large-scale ball-milling production of Pt nanoclusters immobilized on TiO_(2)substrate.The synthesized Pt/Ir@Co_(3)O_(4)catalysts exhibit superior oxygen evolution reaction(OER)performance with only 230 and 290 mV overpotential to achieve current density of 10 and 100 mA·cm^(-2),beating the catalytic performance of Co_(3)O_(4)supported Pt or Ir clusters and commercial Ir/C.It is envisioned that the present work strategically directs facile ways for fabricating supported noble metal heterogeneous catalysts.