Microcirculation of the peripheral nerve is necessary for neural growth and regeneration. However, technical limitations have limited studies in this area. The few studies conducted have concerned active exercise effe...Microcirculation of the peripheral nerve is necessary for neural growth and regeneration. However, technical limitations have limited studies in this area. The few studies conducted have concerned active exercise effects on microcirculation of the peripheral nerve. Using an animal experiment, this study evaluated the effect of swimming training on microcirculation of injured peripheral nerve by laser Doppler flowmetry. The results showed that the blood vessel at the distal end of the peripheral nerve was the main blood supply for the nerve, and the internal blood supply for the nerve had strong compensatory ability. Swimming training promoted the functional recovery of rats with sciatic nerve injury and the regeneration of myelin sheath and blood vessels, but had no impact on neural blood flow.展开更多
Cardiovascular diseases are the major causes of mortality in patients with chronic kidney disease(CKD).The complex process of accelerated athero- and arteriosclerosis in CKD is associated with this phenomenon,where en...Cardiovascular diseases are the major causes of mortality in patients with chronic kidney disease(CKD).The complex process of accelerated athero- and arteriosclerosis in CKD is associated with this phenomenon,where endothelial dysfunction(ED) is one of the initial steps. Hence, the early diagnosis of ED can potentially lead to early interventions which could result in a better outcome for these patients. Several methodologies have been developed for the diagnosis of ED. Laser Doppler flowmetry(LDF) enables us to study the microcirculation continuously in a non-invasive manner. In our review we would like to focus on different tests developed for LDF, like postocclusive reactive hyperaemia,local heating, iontophoresis, microdialysis or analysis of flowmotion. We would also like to summarize the available data in CKD with these methodologies to enlighten their perspectives in the clinical use on this patient population.展开更多
The two-phase detection method for directional discrimination in laser Doppler measurements is discussed.The diffraction efficiency of a sin- gle period rectangular phase grating is analysed and a kind of back-scatter...The two-phase detection method for directional discrimination in laser Doppler measurements is discussed.The diffraction efficiency of a sin- gle period rectangular phase grating is analysed and a kind of back-scattered laser Doppler vibrometer without directional ambiguity using the single peri- od rectangular phase grating as the beam-combiner described.The principles of this kind of vibrometer are explained in detail,and some experimental re- sults are given.In this kind of vibrometer,the rectangular phase grating, without the zero diffracted order and even orders,is used to eliminate use- less stray light and to combine the useful signal light.Differential electronics is employed to reject signal noise.Therefore,the signal-to-noise ratio of Doppler signals and the measurement accuracy of the instrument are im- proved and the range of application is expanded.展开更多
The spatial structure of the velocity field in a stirred vessel with water has been measured and analyzed using the laser Doppler velocimeter technique, with the immersing depth and agitation speed of the impeller re-...The spatial structure of the velocity field in a stirred vessel with water has been measured and analyzed using the laser Doppler velocimeter technique, with the immersing depth and agitation speed of the impeller re-maining approximately constant. The experimental results were provided such as the mean velocity field, fluctuat-ing velocities, turbulent kinetic energy, Reynolds shear stress and time series of the velocity in the stirred tank. These results probably provided the valuable basis to further optimize and enlarge the stirred tank in the industrial process.展开更多
Perfusion of individual tissues is a basic physiological process that is necessary to sustain oxygenation and nutrition at a cellular level. Ischemia, or the insuff iciency of perfusion, is a common mechanism for tiss...Perfusion of individual tissues is a basic physiological process that is necessary to sustain oxygenation and nutrition at a cellular level. Ischemia, or the insuff iciency of perfusion, is a common mechanism for tissue death or degeneration, and at a lower threshold, a mechanism for the generation of sensory signalling including pain. It is of considerable interest to study perfusion of pe- ripheral abdominal tissues in a variety of circumstances. Microvascular disease of the abdominal organs has been implicated in the pathogenesis of a variety of disorders, including peptic ulcer disease, inflammatory bowel disease and chest pain. The basic principle of laser Doppler perfusion monitoring (LDPM) is to analyze changes in the spectrum of light reflected from tissues as a response to a beam of monochromatic laser light emitted. It reflects the total local microcirculatory blood perfusion, including perfusion in capillaries, arterioles, venules and shunts. During the last 20-25 years, numerous studies have been performed in different parts of the gastroin-testinal (GI) tract using LDPM. In recent years we have developed a multi-modal catheter device which includes a laser Doppler probe, with the intent primarily to investigate patients suffering from functional chest pain of presumed oesophageal origin. Preliminary studies show the feasibility of incorporating LDPM into such catheters for performing physiological studies in the GI tract. LDPM has emerged as a research and clinical tool in preference to other methods; but, it is important to be aware of its limitations and account for them when reporting results.展开更多
A laser coherent detection system of 1550 nm wavelength was presented, and experimen- tal research on detecting micro-Doppler effect in a dynamic target was developed. In the study, the return signal in the time domai...A laser coherent detection system of 1550 nm wavelength was presented, and experimen- tal research on detecting micro-Doppler effect in a dynamic target was developed. In the study, the return signal in the time domain is decomposed into a set of components in different wavelet scales by multi-resolution wavelet analysis, and the components are associated with the vibrational motions in a target. Then micro-Doppler signatures are extracted by applying the reconstruction. During the course of the final data processing frequency analysis and time-frequency analysis are applied to analyze the vibrationM signals and estimate the motion parameters successfully. The experimental results indicate that the system can effectively detect micro-Doppler information in a moving target, and the tiny vibrational signatures also can be acquired effectively by wavelet multi-resolution analy- sis and time-frequency analysis.展开更多
Based on laser radar equations, a Doppler shift model of a laser pulse beam scattered by a rotating arbitrary convex target is reported in this paper. The boundary relations between an incident pulse beam and the dete...Based on laser radar equations, a Doppler shift model of a laser pulse beam scattered by a rotating arbitrary convex target is reported in this paper. The boundary relations between an incident pulse beam and the detected area elements are analyzed by geometric methods. The Doppler shift characteristics of the rotating cone and cylinder are discussed and the difference between the laser pulse beam and the plane wave scattered from the same rotating target is compared accordingly. Numerical simulations show that the Doppler shift is tightly relevant to their dimensions, speeds, and so on. In the same incidence conditions, the pulse beam and plane wave have difference peak values and the same Doppler shift bandwidth. If the waist radius of the pulse beam is larger, the peak value is higher, and the Doppler shifts are proportional to the speed of the rotating target. By virtue of our theoretical model, we probe into the scattered characteristics of the Doppler shifts of a laser pulse beam, which would benefit target identification in national defense.展开更多
In the present study a new structural health monitoring (SHM) technique isproposed as well as a new damage index based on 2-D error statistics. The proposedtechnique combines the electromechanical impedance technique ...In the present study a new structural health monitoring (SHM) technique isproposed as well as a new damage index based on 2-D error statistics. The proposedtechnique combines the electromechanical impedance technique (EMI) which is based onthe use of piezoelectric Lead Zirconate Titanate (PZT) patches and Scanning LaserDoppler Vibrometry (SLDV) for damage detection purposes of concrete structures andearly age monitoring. Typically the EMI technique utilizes the direct and inversepiezoelectric effect of a PZT patch attached to a host structure via an impedance analyzerthat is used for both the actuation and sensing the response of the PZT-Host structuresystem. In the proposed technique the attached PZTs are actuated via a function generatorand the PZT-Host structure response is obtained by a Scanning Laser DopplerVibrometer. Spectrums of oscillation velocity of the surface of the attached PZTs verticalto the laser beam versus frequency are obtained and are evaluated for SHM purposes.This damage detection approach also includes the use of a damage index denoted asECAR (Ellipse to Circle Area Ratio) based on 2-D error statistics and is compared to theRoot Mean Square Deviation (RMSD) damage index commonly used in SHMapplications. Experimental results include ascending uniaxial compressive load ofconcrete cubic specimens, ascending three point bending of reinforced concrete beamspecimens and early age monitoring of concrete. Results illustrate the efficiency of theproposed technique in damage detection as well as early age monitoring as, in the firstcase, both severity and location of damage can be determined by examining the values ofdamage indices for each damaged state and in the early age monitoring case damageindices follow the strength gain curve.展开更多
The fundamentals and method of 2 D laser Doppler vibrometer are introduced.The factors influencing the measuring accuracy are analyzed. Moreover, the circuit for signal processing is designed. The vibrating amplitude ...The fundamentals and method of 2 D laser Doppler vibrometer are introduced.The factors influencing the measuring accuracy are analyzed. Moreover, the circuit for signal processing is designed. The vibrating amplitude and frequency of 2 D vibration in wider range can be measured simultaneously in non contact means,the measuring results are accurate.展开更多
Experimental results of remote laser measurement of a time structure of a pulse waves are resulted. Occurrence of the pulse waves are connected with the rhythmic reduction of a myocardittm. Speed of pulse wave's prop...Experimental results of remote laser measurement of a time structure of a pulse waves are resulted. Occurrence of the pulse waves are connected with the rhythmic reduction of a myocardittm. Speed of pulse wave's propagation does not depend on speed of current of blood, it is defined by diameter of a vessel, by its walls thickness, by elasticity of a vessel, and also by rheological properties of blood. Measurement of parameters of pulse waves is important tbr definition of a condition of cardiovascular system. Ways of measurement of characteristics of pulse waves used now (acoustic, electric, optical) are contact. In some cases, for example, in clinics on treatment of burns and so forth, the question of remote measurement of processes hemodynamics by use of methods of laser sotmding is rather actual. The results described in work have shown outlook of development of laser methods of diagnostics for present purposes. The measurement technique used by authors is based on use of longitudinal Doppler effect which essence consists in change of frequency or length of a wave of radiation at reflection from moving surface. For smoothing the measured signal (clearing from noise) the program developed by authors on the basis of the wavelet-analysis was used. Experimental measurements are shown, that the laser method allows to register distinctly structure of pulse waves which is characterized by two peaks. The results of remote laser measurement of a time structure of a pulse waves confirm the assumption made on the basis of general-theoretical physical positions, that characteristics of pulse waves can be registered on the Doppler effect basis.展开更多
粒子速度是分析固体介质中应力波传播规律的一个重要参数。结合激光多普勒效应和全光纤干涉测速系统,提出了一种基于光纤镀膜探针的固体介质中应力波粒子速度的测量方法。将光纤镀膜探针嵌入有机玻璃(PMMA)中,距爆心同一半径处,采用0.12...粒子速度是分析固体介质中应力波传播规律的一个重要参数。结合激光多普勒效应和全光纤干涉测速系统,提出了一种基于光纤镀膜探针的固体介质中应力波粒子速度的测量方法。将光纤镀膜探针嵌入有机玻璃(PMMA)中,距爆心同一半径处,采用0.125 g TNT当量的微型炸药球作为爆炸源,进行填实爆炸产生应力波,通过采集光纤探针端面的运动信息,基于短时傅里叶变换的时频分析方法,解调出端面运动速度,进而反推出粒子速度。实验结果表明:不同光纤镀膜探针测得的速度分别为22.648 m/s、23.505 m/s,将反推的粒子速度与传统的圆环型电磁粒子速度计方法获取到的数据进行对比,两者的相对偏差低于5.00%,验证了光纤镀膜探针测量固体介质中应力波粒子速度的可行性。展开更多
基金the Military Project during "Tenth Five-Year Plan" Period, No.200626Z000058
文摘Microcirculation of the peripheral nerve is necessary for neural growth and regeneration. However, technical limitations have limited studies in this area. The few studies conducted have concerned active exercise effects on microcirculation of the peripheral nerve. Using an animal experiment, this study evaluated the effect of swimming training on microcirculation of injured peripheral nerve by laser Doppler flowmetry. The results showed that the blood vessel at the distal end of the peripheral nerve was the main blood supply for the nerve, and the internal blood supply for the nerve had strong compensatory ability. Swimming training promoted the functional recovery of rats with sciatic nerve injury and the regeneration of myelin sheath and blood vessels, but had no impact on neural blood flow.
文摘Cardiovascular diseases are the major causes of mortality in patients with chronic kidney disease(CKD).The complex process of accelerated athero- and arteriosclerosis in CKD is associated with this phenomenon,where endothelial dysfunction(ED) is one of the initial steps. Hence, the early diagnosis of ED can potentially lead to early interventions which could result in a better outcome for these patients. Several methodologies have been developed for the diagnosis of ED. Laser Doppler flowmetry(LDF) enables us to study the microcirculation continuously in a non-invasive manner. In our review we would like to focus on different tests developed for LDF, like postocclusive reactive hyperaemia,local heating, iontophoresis, microdialysis or analysis of flowmotion. We would also like to summarize the available data in CKD with these methodologies to enlighten their perspectives in the clinical use on this patient population.
文摘The two-phase detection method for directional discrimination in laser Doppler measurements is discussed.The diffraction efficiency of a sin- gle period rectangular phase grating is analysed and a kind of back-scattered laser Doppler vibrometer without directional ambiguity using the single peri- od rectangular phase grating as the beam-combiner described.The principles of this kind of vibrometer are explained in detail,and some experimental re- sults are given.In this kind of vibrometer,the rectangular phase grating, without the zero diffracted order and even orders,is used to eliminate use- less stray light and to combine the useful signal light.Differential electronics is employed to reject signal noise.Therefore,the signal-to-noise ratio of Doppler signals and the measurement accuracy of the instrument are im- proved and the range of application is expanded.
基金Supported by the Natural Science Foundation of Inner Mongolia (No.200408020715).
文摘The spatial structure of the velocity field in a stirred vessel with water has been measured and analyzed using the laser Doppler velocimeter technique, with the immersing depth and agitation speed of the impeller re-maining approximately constant. The experimental results were provided such as the mean velocity field, fluctuat-ing velocities, turbulent kinetic energy, Reynolds shear stress and time series of the velocity in the stirred tank. These results probably provided the valuable basis to further optimize and enlarge the stirred tank in the industrial process.
文摘Perfusion of individual tissues is a basic physiological process that is necessary to sustain oxygenation and nutrition at a cellular level. Ischemia, or the insuff iciency of perfusion, is a common mechanism for tissue death or degeneration, and at a lower threshold, a mechanism for the generation of sensory signalling including pain. It is of considerable interest to study perfusion of pe- ripheral abdominal tissues in a variety of circumstances. Microvascular disease of the abdominal organs has been implicated in the pathogenesis of a variety of disorders, including peptic ulcer disease, inflammatory bowel disease and chest pain. The basic principle of laser Doppler perfusion monitoring (LDPM) is to analyze changes in the spectrum of light reflected from tissues as a response to a beam of monochromatic laser light emitted. It reflects the total local microcirculatory blood perfusion, including perfusion in capillaries, arterioles, venules and shunts. During the last 20-25 years, numerous studies have been performed in different parts of the gastroin-testinal (GI) tract using LDPM. In recent years we have developed a multi-modal catheter device which includes a laser Doppler probe, with the intent primarily to investigate patients suffering from functional chest pain of presumed oesophageal origin. Preliminary studies show the feasibility of incorporating LDPM into such catheters for performing physiological studies in the GI tract. LDPM has emerged as a research and clinical tool in preference to other methods; but, it is important to be aware of its limitations and account for them when reporting results.
文摘A laser coherent detection system of 1550 nm wavelength was presented, and experimen- tal research on detecting micro-Doppler effect in a dynamic target was developed. In the study, the return signal in the time domain is decomposed into a set of components in different wavelet scales by multi-resolution wavelet analysis, and the components are associated with the vibrational motions in a target. Then micro-Doppler signatures are extracted by applying the reconstruction. During the course of the final data processing frequency analysis and time-frequency analysis are applied to analyze the vibrationM signals and estimate the motion parameters successfully. The experimental results indicate that the system can effectively detect micro-Doppler information in a moving target, and the tiny vibrational signatures also can be acquired effectively by wavelet multi-resolution analy- sis and time-frequency analysis.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61271110,60801047,and 61073106)the New Scientific and TechnologicalStar Project of Shaanxi Province,China(Grant No.2011KJXX39)+1 种基金the Aviation Science Foundation(Grant No.2011ZC53042)the Natural ScienceFoundation of Shaanxi Province,China(Grant Nos.12Jk0955 and 2014JQ0816)
文摘Based on laser radar equations, a Doppler shift model of a laser pulse beam scattered by a rotating arbitrary convex target is reported in this paper. The boundary relations between an incident pulse beam and the detected area elements are analyzed by geometric methods. The Doppler shift characteristics of the rotating cone and cylinder are discussed and the difference between the laser pulse beam and the plane wave scattered from the same rotating target is compared accordingly. Numerical simulations show that the Doppler shift is tightly relevant to their dimensions, speeds, and so on. In the same incidence conditions, the pulse beam and plane wave have difference peak values and the same Doppler shift bandwidth. If the waist radius of the pulse beam is larger, the peak value is higher, and the Doppler shifts are proportional to the speed of the rotating target. By virtue of our theoretical model, we probe into the scattered characteristics of the Doppler shifts of a laser pulse beam, which would benefit target identification in national defense.
文摘In the present study a new structural health monitoring (SHM) technique isproposed as well as a new damage index based on 2-D error statistics. The proposedtechnique combines the electromechanical impedance technique (EMI) which is based onthe use of piezoelectric Lead Zirconate Titanate (PZT) patches and Scanning LaserDoppler Vibrometry (SLDV) for damage detection purposes of concrete structures andearly age monitoring. Typically the EMI technique utilizes the direct and inversepiezoelectric effect of a PZT patch attached to a host structure via an impedance analyzerthat is used for both the actuation and sensing the response of the PZT-Host structuresystem. In the proposed technique the attached PZTs are actuated via a function generatorand the PZT-Host structure response is obtained by a Scanning Laser DopplerVibrometer. Spectrums of oscillation velocity of the surface of the attached PZTs verticalto the laser beam versus frequency are obtained and are evaluated for SHM purposes.This damage detection approach also includes the use of a damage index denoted asECAR (Ellipse to Circle Area Ratio) based on 2-D error statistics and is compared to theRoot Mean Square Deviation (RMSD) damage index commonly used in SHMapplications. Experimental results include ascending uniaxial compressive load ofconcrete cubic specimens, ascending three point bending of reinforced concrete beamspecimens and early age monitoring of concrete. Results illustrate the efficiency of theproposed technique in damage detection as well as early age monitoring as, in the firstcase, both severity and location of damage can be determined by examining the values ofdamage indices for each damaged state and in the early age monitoring case damageindices follow the strength gain curve.
文摘The fundamentals and method of 2 D laser Doppler vibrometer are introduced.The factors influencing the measuring accuracy are analyzed. Moreover, the circuit for signal processing is designed. The vibrating amplitude and frequency of 2 D vibration in wider range can be measured simultaneously in non contact means,the measuring results are accurate.
文摘Experimental results of remote laser measurement of a time structure of a pulse waves are resulted. Occurrence of the pulse waves are connected with the rhythmic reduction of a myocardittm. Speed of pulse wave's propagation does not depend on speed of current of blood, it is defined by diameter of a vessel, by its walls thickness, by elasticity of a vessel, and also by rheological properties of blood. Measurement of parameters of pulse waves is important tbr definition of a condition of cardiovascular system. Ways of measurement of characteristics of pulse waves used now (acoustic, electric, optical) are contact. In some cases, for example, in clinics on treatment of burns and so forth, the question of remote measurement of processes hemodynamics by use of methods of laser sotmding is rather actual. The results described in work have shown outlook of development of laser methods of diagnostics for present purposes. The measurement technique used by authors is based on use of longitudinal Doppler effect which essence consists in change of frequency or length of a wave of radiation at reflection from moving surface. For smoothing the measured signal (clearing from noise) the program developed by authors on the basis of the wavelet-analysis was used. Experimental measurements are shown, that the laser method allows to register distinctly structure of pulse waves which is characterized by two peaks. The results of remote laser measurement of a time structure of a pulse waves confirm the assumption made on the basis of general-theoretical physical positions, that characteristics of pulse waves can be registered on the Doppler effect basis.
文摘粒子速度是分析固体介质中应力波传播规律的一个重要参数。结合激光多普勒效应和全光纤干涉测速系统,提出了一种基于光纤镀膜探针的固体介质中应力波粒子速度的测量方法。将光纤镀膜探针嵌入有机玻璃(PMMA)中,距爆心同一半径处,采用0.125 g TNT当量的微型炸药球作为爆炸源,进行填实爆炸产生应力波,通过采集光纤探针端面的运动信息,基于短时傅里叶变换的时频分析方法,解调出端面运动速度,进而反推出粒子速度。实验结果表明:不同光纤镀膜探针测得的速度分别为22.648 m/s、23.505 m/s,将反推的粒子速度与传统的圆环型电磁粒子速度计方法获取到的数据进行对比,两者的相对偏差低于5.00%,验证了光纤镀膜探针测量固体介质中应力波粒子速度的可行性。