Molecular dynamics simulations are employed to investigate the effect of thermal convection induced only by dissipative lateral walls on density segregation of the strongly driven binary granular gases under low gravi...Molecular dynamics simulations are employed to investigate the effect of thermal convection induced only by dissipative lateral walls on density segregation of the strongly driven binary granular gases under low gravity conditions. It is found that the thermal convection due to dissipative lateral walls has significant influence on the segregation intensity of the system. The dominant factor in determining the degree of segregation achieved by the system is found to be the relative convection rate between differing species. Moreover, a qualitative explanation is proposed for the relationship between the thermal convection due to dissipative lateral walls and the observed segregation intensity profiles.展开更多
Purpose:Intramedullary implants are well accepted fixation of all types of intertrochanteric(IT)frac-tures,both stable and unstable types.Intramedullary nails have an ability to effectively support the posteromedial p...Purpose:Intramedullary implants are well accepted fixation of all types of intertrochanteric(IT)frac-tures,both stable and unstable types.Intramedullary nails have an ability to effectively support the posteromedial part,but fail to buttress the broken lateral wall requiring lateral augmentation.The aim of this study was to evaluate the outcome of proximal femoral nail augmented with trochanteric buttress plate for broken lateral wall with IT fractures,which was fixed to the femur through hip screw and anti-rotation screw nail.Methods:Of 30 patients,20 had Jensen-Evan typeⅢand 10 had type V fractures.Patients with IT fracture of broken lateral wall and aged more than 18 years,in whom satisfactory reduction was achieved by closed methods,were included in the study.Patients with pathologic or open fractures,polytrauma,prior hip surgery,non-ambulatory prior to surgery,and those who refused to participate were excluded.The operative time,blood loss,radiation exposure,quality of reduction,functional outcome,and union time were evaluated.All data were coded and recorded in Microsoft Excel spread sheet program.SPSS 20.0 was used for data analysis and normality of the continuous data was checked using Kolmogorv Smirnov test.Results:The mean age of patients in the study was 60.3 years.The mean duration of surgery(min),mean intra-operative blood loss(mL)and mean number of exposures were 91.86±12.8(range 70-122),144.8±3.6(range 116-208),and 56.6(range 38-112),respectively.The mean union time was 11.6 weeks and the mean Harris hip score was 94.1.Conclusion:Lateral trochanteric wall in IT fractures is significantly important,and needs to be recon-structed adequately.Nail-plate construct of trochanteric buttress plate fixed with hip screw and anti-rotation screw of proximal femoral nail can be successfully used to augment,fix or buttress the lateral trochanteric wall giving excellent to good results of early union and reduction.展开更多
Hip fractures,especially intertrochanteric fractures,are more common with aging.After decades of progress,it is a general consensus to carry out internal fixation for this group of patients.However,the recent focus is...Hip fractures,especially intertrochanteric fractures,are more common with aging.After decades of progress,it is a general consensus to carry out internal fixation for this group of patients.However,the recent focus is on unstable intertrochanteric fractures to ensure better prognosis and prevent internal fixation failure.The lateral femoral wall,as a novel concept,is often disregarded.Many scholars have recognized that the lateral wall of the proximal femoral plays a crucial role in the stability of internal fixation for intertrochanteric fractures.In this paper,the historical evolution,definition,clinical significance,injury classification,choice of internal fixation,and possible prognosis of lateral femoral wall fracture are reviewed in order to provide clinicians strong evidence of treatment strategies.展开更多
Back-to-back mechanically stabilized earth walls （BBMSEWs） are encountered in bridge approaches, ramp ways, rockfall protection systems, earth dams, levees and noise barriers. However, available design guidelines fo...Back-to-back mechanically stabilized earth walls （BBMSEWs） are encountered in bridge approaches, ramp ways, rockfall protection systems, earth dams, levees and noise barriers. However, available design guidelines for BBMSEWs are limited and not applicable to numerical modeling when back-to-back walls interact with each other. The objective of this paper is to investigate, using PLAXIS code, the effects of the reduction in the distance between BBMSEW, the reinforcement length, the quality of backfill material and the connection of reinforcements in the middle, when the back-to-back walls are close. The results indicate that each of the BBMSEWs behaves independently if the width of the embankment between mechanically stabilized earth walls is greater than that of the active zone. This is in good agreement with the result of FHWA design guideline. However, the results show that the FHWA design guideline underestimates the lateral earth pressure when back-to-back walls interact with each other. Moreover, for closer BBMSEWs, FHWA design guideline strongly overestimates the maximum tensile force in the reinforcement. The investigation of the quality of backfill material shows that the minor increase in embankment cohesion can lead to significant reductions in both the lateral earth pressure and the maximum tensile force in geosynthetic. When the distance between the two earth walls is close to zero, the connection of reinforcement between back-to-back walls significantly improves the factor of safety.展开更多
The stress response theory is a relatively new concept about the cause of idiopathic sudden sensorineural hearing loss(ISHL). A number of possible etiologies have been proposed in the literature, as discussed in this ...The stress response theory is a relatively new concept about the cause of idiopathic sudden sensorineural hearing loss(ISHL). A number of possible etiologies have been proposed in the literature, as discussed in this paper, but each proposed etiology has been both supported and refuted in the literature. However, the stress response theory can integrate hypotheses that have been advocated so far. The word "stress" refers to a constellation of physical and psychological stimuli including systemic viral and bacterial illness, systemic inflammatory disorders, and physical, mental or metabolic stress. Numerous studies have demonstrated adverse effects of systemic stress on health. Stress causes changes in the immune system and cytokine network through activation of the hypothalamus-pituitary-adrenal axis and the sympathetic nervous system. Several types of catecholamine and cytokine receptors are in the cochlea cells other than capillary cells, and then they can respond to systemic stressors. However, there are few studies examining how systemic stress is associated with cochlear dysfunction. The stress response theory addresses this question. In the theory, a variety of stressors and risk factors contribute to the onset of ISHL in varying degrees. The lateral wall of the cochlea has very unique responses to systemic stressors. It plays a critical role in causing ISHL. Systemic stressors converge at the lateral wall and trigger pathological activation of nuclear factor κ-light-chain-enhancer of activated B cells, a transcriptional factor known as a stress sensor. This activation enhances local expression of genes associated with immune and inflammatory system, resulting in cochlear dysfunction. We review the original stress response theory advocated by Adams et al and the integrative stress response theory that integrates our knowledge about the etiologies of ISHL so far.展开更多
基金Supported by the National Natural Science Foundation of China under Grant No 11404104the Natural Science Foundation of Hubei Province of China under Grant No 2014CFC1127
文摘Molecular dynamics simulations are employed to investigate the effect of thermal convection induced only by dissipative lateral walls on density segregation of the strongly driven binary granular gases under low gravity conditions. It is found that the thermal convection due to dissipative lateral walls has significant influence on the segregation intensity of the system. The dominant factor in determining the degree of segregation achieved by the system is found to be the relative convection rate between differing species. Moreover, a qualitative explanation is proposed for the relationship between the thermal convection due to dissipative lateral walls and the observed segregation intensity profiles.
文摘Purpose:Intramedullary implants are well accepted fixation of all types of intertrochanteric(IT)frac-tures,both stable and unstable types.Intramedullary nails have an ability to effectively support the posteromedial part,but fail to buttress the broken lateral wall requiring lateral augmentation.The aim of this study was to evaluate the outcome of proximal femoral nail augmented with trochanteric buttress plate for broken lateral wall with IT fractures,which was fixed to the femur through hip screw and anti-rotation screw nail.Methods:Of 30 patients,20 had Jensen-Evan typeⅢand 10 had type V fractures.Patients with IT fracture of broken lateral wall and aged more than 18 years,in whom satisfactory reduction was achieved by closed methods,were included in the study.Patients with pathologic or open fractures,polytrauma,prior hip surgery,non-ambulatory prior to surgery,and those who refused to participate were excluded.The operative time,blood loss,radiation exposure,quality of reduction,functional outcome,and union time were evaluated.All data were coded and recorded in Microsoft Excel spread sheet program.SPSS 20.0 was used for data analysis and normality of the continuous data was checked using Kolmogorv Smirnov test.Results:The mean age of patients in the study was 60.3 years.The mean duration of surgery(min),mean intra-operative blood loss(mL)and mean number of exposures were 91.86±12.8(range 70-122),144.8±3.6(range 116-208),and 56.6(range 38-112),respectively.The mean union time was 11.6 weeks and the mean Harris hip score was 94.1.Conclusion:Lateral trochanteric wall in IT fractures is significantly important,and needs to be recon-structed adequately.Nail-plate construct of trochanteric buttress plate fixed with hip screw and anti-rotation screw of proximal femoral nail can be successfully used to augment,fix or buttress the lateral trochanteric wall giving excellent to good results of early union and reduction.
文摘Hip fractures,especially intertrochanteric fractures,are more common with aging.After decades of progress,it is a general consensus to carry out internal fixation for this group of patients.However,the recent focus is on unstable intertrochanteric fractures to ensure better prognosis and prevent internal fixation failure.The lateral femoral wall,as a novel concept,is often disregarded.Many scholars have recognized that the lateral wall of the proximal femoral plays a crucial role in the stability of internal fixation for intertrochanteric fractures.In this paper,the historical evolution,definition,clinical significance,injury classification,choice of internal fixation,and possible prognosis of lateral femoral wall fracture are reviewed in order to provide clinicians strong evidence of treatment strategies.
文摘Back-to-back mechanically stabilized earth walls （BBMSEWs） are encountered in bridge approaches, ramp ways, rockfall protection systems, earth dams, levees and noise barriers. However, available design guidelines for BBMSEWs are limited and not applicable to numerical modeling when back-to-back walls interact with each other. The objective of this paper is to investigate, using PLAXIS code, the effects of the reduction in the distance between BBMSEW, the reinforcement length, the quality of backfill material and the connection of reinforcements in the middle, when the back-to-back walls are close. The results indicate that each of the BBMSEWs behaves independently if the width of the embankment between mechanically stabilized earth walls is greater than that of the active zone. This is in good agreement with the result of FHWA design guideline. However, the results show that the FHWA design guideline underestimates the lateral earth pressure when back-to-back walls interact with each other. Moreover, for closer BBMSEWs, FHWA design guideline strongly overestimates the maximum tensile force in the reinforcement. The investigation of the quality of backfill material shows that the minor increase in embankment cohesion can lead to significant reductions in both the lateral earth pressure and the maximum tensile force in geosynthetic. When the distance between the two earth walls is close to zero, the connection of reinforcement between back-to-back walls significantly improves the factor of safety.
基金Supported by A grant from the Ministry of Health,Labor and Welfare and a Grant-in-Aid for Young Scientists
文摘The stress response theory is a relatively new concept about the cause of idiopathic sudden sensorineural hearing loss(ISHL). A number of possible etiologies have been proposed in the literature, as discussed in this paper, but each proposed etiology has been both supported and refuted in the literature. However, the stress response theory can integrate hypotheses that have been advocated so far. The word "stress" refers to a constellation of physical and psychological stimuli including systemic viral and bacterial illness, systemic inflammatory disorders, and physical, mental or metabolic stress. Numerous studies have demonstrated adverse effects of systemic stress on health. Stress causes changes in the immune system and cytokine network through activation of the hypothalamus-pituitary-adrenal axis and the sympathetic nervous system. Several types of catecholamine and cytokine receptors are in the cochlea cells other than capillary cells, and then they can respond to systemic stressors. However, there are few studies examining how systemic stress is associated with cochlear dysfunction. The stress response theory addresses this question. In the theory, a variety of stressors and risk factors contribute to the onset of ISHL in varying degrees. The lateral wall of the cochlea has very unique responses to systemic stressors. It plays a critical role in causing ISHL. Systemic stressors converge at the lateral wall and trigger pathological activation of nuclear factor κ-light-chain-enhancer of activated B cells, a transcriptional factor known as a stress sensor. This activation enhances local expression of genes associated with immune and inflammatory system, resulting in cochlear dysfunction. We review the original stress response theory advocated by Adams et al and the integrative stress response theory that integrates our knowledge about the etiologies of ISHL so far.
