China-Latin America Green Cooperation under the Global Development Initiative

The international development environment is entering a chaotic and volatile period.The world economy remains sluggish,while geopolitical conflicts,climate change,food crisis and a multitude of other challenges become more closely intertwined and mutually reinforcing.In this context,countries across the world have been prompted to look for healthy,feasible and sustainable solutions to keep their socioeconomic development momentum on track.

Sociodemographic determinants associated with breastfeeding in term infants with low birth weight in Latin American countries

BACKGROUND A progressive decrease in exclusive breastfeeding(BF)is observed in Latin America and the Caribbean compared with global results.The possibility of being breastfed and continuing BF for>6 months is lower in low birth weight than in healthy-weight infants.AIM To identify factors associated with BF maintenance and promotion,with particular attention to low-and middle-income countries,by studying geographic,socioeconomic,and individual or neonatal health factors.METHODS A scoping review was conducted in 2018 using the conceptual model of social determinants of health published by the Commission on Equity and Health Inequalities in the United States.The extracted data with common characteristics were synthesized and categorized into two main themes:(1)Sociodemographic factors and proximal determinants involved in the initiation and maintenance of BF in low-birth-weight term infants in Latin America;and(2)individual characteristics related to the self-efficacy capacity for BF maintenance and adherence in low-birth-weight term infants.RESULTS This study identified maternal age,educational level,maternal economic capacity,social stratum,exposure to BF substitutes,access to BF information,and quality of health services as mediators for maintaining BF.CONCLUSION Individual self-efficacy factors that enable BF adherence in at-risk populations should be analyzed for better health outcomes.

基于Latin方抽样和修正的Latin方抽样的可靠性灵敏度估计及其方差分析

运用Latin方抽样(Latin hypercube sampling)方法和经统计相关减小方程修正后的Latin方抽样(updated Latin hypercube sampling)方法对结构进行可靠性灵敏度估计及其方差分析。单模式和多模式的数值及工程算例说明,可靠性灵敏度分析的Latin方抽样和修正的Latin方抽样在样本容量较小时都可以得到比Monte Carlo抽样方法更稳定的估计结果。采用Latin方抽样可以得到可靠性灵敏度的无偏估计,而修正的Latin方抽样方法在样本容量较小的情况下得到的可靠性灵敏度估计值的方差的分散性较Latin方抽样有进一步的减小。Latin方抽样和修正的Latin方抽样方法对基本变量的分布形式和相关性等均无限定,是适用于结构可靠性灵敏度分析的一种有效而实用的小样本抽样方法。

Mitochondria–cGAS–STING axis is a potential therapeutic target for senescence-dependent inflammaging-associated neurodegeneration

The word “senescence” comes from the Latin senescens, meaning “to begin to age”, and is characterized by a long-lasting but reversible block in proliferation, resulting from stress-induced cell cycle arrest of previously replication-competent cells.

Latin抽样法在导弹结构裂纹概率仿真中的应用

提出了Ｌａｔｉｎ抽样与分层抽样相结合的复合抽样方法，对于提高抽样精度和效率都有较为明显的作用，特别适用于结构裂纹概率的仿真和其它应用工程仿真计算。在复合抽样仿真计算示例中，对某型导弹的燃汽发生器进行了抽样仿真计算，所得的抽样结果的精度和相关差都达到了令人满意的预期效果，与实验结果吻合。

Application of the optimal Latin hypercube design and radial basis function network to collaborative optimization

Improving the efficiency of ship optimization is crucial for modem ship design. Compared with traditional methods, multidisciplinary design optimization （MDO） is a more promising approach. For this reason, Collaborative Optimization （CO） is discussed and analyzed in this paper. As one of the most frequently applied MDO methods, CO promotes autonomy of disciplines while providing a coordinating mechanism guaranteeing progress toward an optimum and maintaining interdisciplinary compatibility. However, there are some difficulties in applying the conventional CO method, such as difficulties in choosing an initial point and tremendous computational requirements. For the purpose of overcoming these problems, optimal Latin hypercube design and Radial basis function network were applied to CO. Optimal Latin hypercube design is a modified Latin Hypercube design. Radial basis function network approximates the optimization model, and is updated during the optimization process to improve accuracy. It is shown by examples that the computing efficiency and robustness of this CO method are higher than with the conventional CO method.

Role of gene polymorphisms in gastric cancer and its precursor lesions:Current knowledge and perspectives in Latin American countries

Latin America shows one of the highest incidence rates of gastric cancer in the world,with variations in mortality rates among nations or even within countries belonging to this region.Gastric cancer is the result of a multifactorial complex process,for which a multistep model of carcinogenesis is currently accepted.Additionally to the infection with Helicobacter pylori,that plays a major role,environmental factors as well as genetic susceptibility factors are significant players at different stages in the gastric cancer process.The differences in population origin,demographic structure,socio-economic development,and the impact of globalization lifestyles experienced in Latin America in the last decades,all together offer opportunities for studying in this context the influence of genetic polymorphisms in the susceptibility to gastric cancer.The aim of this article is to discuss current trends on gastric cancer in Latin American countries and to review the available published information about studies of association of gene polymorphisms involved in gastric cancer susceptibility from this region of the world.A total of 40 genes or genomic regions and69 genetic variants,58%representing markers involved in inflammatory response,have been used in a number of studies in which predominates a low number of individuals(cases and controls)included.Polymorphisms of IL-1B(-511 C/T,14 studies;-31 T/C,10 studies)and IL-1RN(variable number of tandem repeats,17 studies)are the most represented ones in the reviewed studies.Other genetic variants recently evaluated in large metaanalyses and associated with gastric cancer risk were also analyzed in a few studies[e.g.,prostate stem cell antigen(PSCA),CDH1,Survivin].Further and better analysis centered in gene polymorphisms linked to other covariates,epidemiological studies and the information provided by meta-analyses and genome-wide association studies should help to improve our understanding of gastric cancer etiology in order to develop appropriate health programs in Latin America.

Helicobacter pylori recurrence after eradication in Latin America:Implications for gastric cancer prevention

To estimate Helicobacter pylori (H. pylori) recurrence rate in Latin America, a region with a significant H. pylori prevalence and gastric cancer burden. METHODSPubMed, LILACS, SciELO, Cochrane databases and abstracts from relevant meetings were reviewed. Information collected included: Participants’ characteristics, recruitment strategy, diagnostic modality, treatment arms, follow-up and recurrence rates. Recurrence was calculated using 100-patients-year rates, and data were pooled using a random effects model. The I2 statistic assessed between study heterogeneity. Meta-regression analyses evaluated for effect modifying variables. RESULTSLiterature search yielded 163 articles. Twelve studies involving 4848 patients from 9 countries met inclusion criteria. Four hundred and thirty-two reinfections were recorded in 5487 person-years of follow-up. Pooled analysis showed a recurrence rate of 7.9 cases per 100 person-years (95%CI: 5.3-10.5). Meta-regression revealed that neither the antibiotic schema, a second antibiotic course, nor the diagnostic modality had an impact on the observed risk of recurrence. The recurrence rate in the first year after treatment, predominantly recrudescence, was 11.2 (6.1-16.4) per 100 patient years. Recurrence in subsequent years, was only 6.2 (3.8-8.7). CONCLUSIONH. pylori recurrence rates in Latin America are significant, and with geographic variability, yet are acceptable based upon the current literature for consideration of large scale intervention trials. Further research in Latin America is warranted to evaluate the efficacy, cost-effectiveness, and potential adverse outcomes of proposed eradication programs.

Hepatocellular carcinoma in Latin America: Diagnosis and treatment challenges

Latin America, a region with a population greater than 600000000 individuals, is well known due to its wide geographic, socio-cultural and economic heterogeneity. Access to health care remains as the main barrier that challenges routine screening, early diagnosis and proper treatment of hepatocellular carcinoma(HCC). Therefore, identification of population at risk, implementation of surveillance programs and access to curative treatments has been poorly obtained in the region. Different retrospective cohort studies from the region have shown flaws in the implementation process of routine surveillance and early HCC diagnosis. Furthermore, adherence to clinical practice guidelines recommendations assessed in two studies from Brazil and Argentina demonstrated that there is also room for improvement in this field, similarly than the one observed in Europe and the United States. In summary, Latin America shares difficulties in HCC decision-making processes similar to those from developed countries. However, a transversal limitation in the region is the poor access to health care with the consequent limitation to standard treatments for overall population. Specifically, universal health care access to the different World Health Organization levels is crucial, including improvement in research, education and continuous medical training in order to expand knowledge and generation of data promoting a continuous improvement in the care of HCC patients.

Hepatitis B virus infection in Latin America:A genomic medicine approach

Hepatitis B virus(HBV)infection is the leading cause of severe chronic liver disease.This article provides a critical view of the importance of genomic medicine for the study of HBV infection and its clinical outcomes in Latin America.Three levels of evolutionary adaptation may correlate with the clinical outcomes of HBV infection.Infections in Latin America are predominantly of genotype H in Mexico and genotype F in Central and South America;these strains have historically circulated among the indigenous population.Both genotypes appear to be linked to a benign course of disease among the native and mestizo Mexicans and native South Americans.In contrast,genotypes F,A and D are common in acute and chronic infections among mestizos with Caucasian ancestry.Hepatocellular carcinoma is rare in Mexicans,but it has been associated with genotype F1b among Argentineans.This observation illustrates the significance of ascertaining the genetic and environmental factors involved in the development of HBV-related liver disease in Latin America,which contrast with those reported in other regions of the world.

Management of Helicobacter pylori infection in Latin America: A Delphi technique-based consensus

AIM: To optimize diagnosis and treatment guidelines for this geographic region, a panel of gastroenterologists, epidemiologists, and basic scientists carried out a structured evaluation of available literature.

Dissemination of Traditional Chinese Medicine in Latin America and the Caribbean: the Cases of Peru, Chile, and Cuba

Traditional Chinese medicine(TCM) arrived from China to Latin America and the Caribbean in the 1840s due to the massive migration of Chinese people to the region. In a few years, the press noticed the presence of Chinese herbalists practicing in different cities and countries regardless of the demographic weight of the Chinese community. The fascination with Chinese doctors implicated not only the press but also the literature, a phenomenon particularly observed in Cuba. In the first decades of the 20th century, the reactivation of Chinese immigration to the region fostered an anti-Chinese climate that materialized in more significant migratory restrictions and control of their businesses, such as what happened with Chinese herbalists. These herbalists who practiced inside and outside the Chinese community started to object to criticism and persecution by the conservative press and professional doctors. Despite this, Chinese doctors will continue to maintain their support of a significant number of ill persons. This work seeks to illuminate the historical relevance of TCM in Latin America and the Caribbean, focusing on the cases of Peru, Chile, and Cuba. This last country was far from China culturally and geographically, but as in many other small towns in the region, Chinese medicine presented an alternative to the treatment of illnesses.

Latin方阵和二维量子漫步相结合的图像加密

针对数字图像在网络传输过程中容易受到攻击导致信息泄漏的问题,在Arnold置乱变换的基础上引入量子漫步和Latin方阵,设计了一种新型的彩色图像加密方案。首先把彩色图像的三通道分离,用Arnold变换来对图像像素点置乱,量子漫步和Latin方阵被用来处理置乱后图像的像素值,然后对处理之后的图像使用加取模扩散算法进一步改变图像的像素值,最后合并三通道加密图像得到彩色加密图像。量子漫步的作用是为该文的加密算法提供随机序列。该文对加密算法进行了实验仿真,在直方图、相关性、信息熵、噪声攻击、裁剪攻击等多个方面对实验结果进行了性能分析。仿真结果显示:加密图像的直方图均匀分布,像素点之间的相关性趋近于0,信息熵为7.9993,接近于8,说明该算法具有较不错的抵抗统计分析的能力;经过噪声攻击和裁剪攻击之后的加密图像经过解密之后,仍然可以看到原图像信息,表明该算法的鲁棒性是良好的;该加密算法的密钥空间足够大为1060且密钥敏感性良好,NPCR值接近于99.61%,UACI值接近于33.45%,证明该算法拥有抵抗差分攻击的能力。

Research Priorities and the Future of Alfalfa in Latin America

Agro-food and agro-industrial systems in Latin America must anticipate future trends and ensure permanent adjustment ofresearch priorities to the evolving global needs. Innovations should follow the logic of productive chains, which are highly dependentupon knowledge and technology. Agribusiness sector needs to reinvent itself for efficiently providing new products based on stricterquality controls, traceability, and greater diversification. In the region, alfalfa has an enormous potential to be cultivated for multiplepurposes other than just animal products, going from pharmaceutical and cosmetic industry to human consumption. No singleorganization or isolated group of scientists hold alone the capacity to deal with increasingly complex and dynamic productionsystems in order to efficiently compete in a globalized market. These challenges require an interdisciplinary approach, not only to adomestic level but also to an international one. The present paper proposed the constitution of a virtual alfalfa network platform forarticulating and guiding alfalfa research efforts in Latin America. The network will focus on identifying the most important needs forLatin America, promoting an active interaction among educational and scientific institutions through collaborative research projects.The platform comprises four main research axes: (1) efficient production (agronomy);(2) animal production (diversified feeds);(3)quality and innocuousness applied (human feeding);(4) novel products (pharmaceutical and cosmetics). During the initial phase, theBrazilian Agricultural Research Corporation (EMBRAPA, Brazil) and National Institute of Agricultural Technology (INTA,Argentina) will jointly coordinate the network.

Institutions and Intellectuals That Configure the Concept of the Environment and Development in Latin America and Its Global Impact

This paper is part of a research into the Latin American thinking on international affairs and a continuation of a line of work on Latin American contributions to the environmental discussion installed in the global political agenda in the early 70s. The premise was that Latin American contributions were initially made by professionals closely related to ECLAC, UNEP and the Bariloche Foundation. These professionals and agencies understood how poverty and backwardness were endured by the majority of the regional and world’s population was one of the main causes of environmental degradation;consequently, overcoming the environmental crisis meant that underdevelopment should be eradicated without delay. This view of the environmental problems was synthesized in the combined concept of “environment and development”, which was also understood in the region as “eco development”. Finally, the broad phenomenon they wanted to describe using the terms “environment and development” was summarized in the concept of sustainable development as defined in the 1987 World Commission on Environment and Development report “Our Common Future”.

A CASCADING LATIN SCHEME TO TOLERATE DOUBLE DISK FAILURES IN RAID ARCHITECTURES

In recent years,a lot of XOR-based coding schemes have been developed to tolerate double disk failures in Redundant Array of Independent Disks (RAID) architectures,such as EVENODD-code,X-code,B-code and BG-HEDP. Despite those researches,the decades-old strategy of Reed-Solomon (RS) code remains the only popular space-optimal Maximum Distance Separable (MDS) code for all but the smallest storage systems. The reason is that all those XOR-based schemes are too difficult to be implemented,it mainly because the coding-circle of those codes vary with the number of disks. By contrast,the coding-circle of RS code is a constant. In order to solve this problem,we develop a new MDS code named Latin code and a cascading scheme based on Latin code. The cascading Latin scheme is a nearly MDS code (with only one or two more parity disks compared with the MDS ones). Nev-ertheless,it keeps the coding-circle of the basic Latin code (i.e. a constant) and the low encod-ing/decoding complexity similar to other parity array codes.

Chinese Investment in Latin American Resources

China’s need for vast amounts of minerals to sustain its high economic growth rate has increasingly turned Chinese investors towards Latin America.This demand has propelled China into third place among Latin American investors,directing over $15 billion (about

基于Pig Latin语言的海量数据分析

随着互联网的飞速发展,分析海量数据的需求变得十分迫切。针对分布式数据库昂贵及Map-Reduce计算框架中代码难以维护、重用等问题,雅虎研发了自己的海量数据分析平台Pig。Pig平台基于Hadoop的Map-Reduce计算框架并提供类SQL的命令式查询语言Pig Latin,该平台为复杂的海量数据并行计算提供了简易的操作和编程接口。本文对Pig Latin语言四种数据模型、常用表达式及关键操作符进行介绍,并结合实例对Pig Latin脚本程序进行分析。

Understanding the Urban Sprawl in the Mid-Size Latin American Cities through the Urban Form:Analysis of the Concepcion Metropolitan Area(Chile)

Latin American cities, like those from North America and Europe, experience problems of urban sprawl. However, few studies have dedicated exclusively to this phenomenon in specific cities, and this omission is particularly noticeable regarding cities not considered among the megalopolis of the continent. The present work analyzes urban sprawl through an urban form in the Concepción Metropolitan Area, Chile, between 1990 and 2009, considering local aspects that may have played a role in the process. The main empirical results obtained from this study reveal a metropolitan area that has expanded intensely over a 20-year period, growing from 9000 hectares to more than 17,000 ha for a 96% increment in the built-up area. The new urban surfaces consolidate a central conurbation that strengthens the role of the main downtowns, with less-intense occupation towards the sub-centers but in a structure that follows the transportation infrastructure. Over the last 20 years, the distance between the shapes has grown progressively by around 2 km, increasing the size of the ellipse by more than 1000 km2. In particular the complexity of the urbanized surfaces has grown, becoming more irregular in shape and less compact as they come to occupy larger areas. So our principal findings include: an increment of nearly 100% in the urban surface, the importance of a polycentric urban structure in the process of consolidation as a support for analyzing different spatial dynamics, and the growing morphological irregularity of the territory of the sprawl.

Multidisciplinary Design and Optimization of Satellite Launch Vehicle Using Latin Hypercube Design of Experiments

The design of new Satellite Launch Vehicle （SLV） is of interest, especially when a combination of Solid and Liquid Propulsion is included. Proposed is a conceptual design and optimization technique for multistage Low Earth Orbit （LEO） bound SLV comprising of solid and liquid stages with the use of Genetic Algorithm （GA） as global optimizer. Convergence of GA is improved by introducing initial population based on the Design of Experiments （DOE） Technique. Latin Hypercube Sampling （LHS）-DOE is used for its good space filling properties. LHS is a stratified random procedure that provides an efficient way of sampling variables from their multivariate distributions. In SLV design minimum Gross Lift offWeight （GLOW） concept is traditionally being sought. Since the development costs tend to vary as a function of GLOW, this minimum GLOW is considered as a minimum development cost concept. The design approach is meaningful to initial design sizing purpose for its computational efficiency gives a quick insight into the vehicle performance prior to detailed design.