Fluid shortening is an important ingredient in the production of sponge cake. Peanut oil with 0, 43% and 85% of diacylglycerol content was used as the base oil. Different emulsifiers, such as glycerol monostearate, so...Fluid shortening is an important ingredient in the production of sponge cake. Peanut oil with 0, 43% and 85% of diacylglycerol content was used as the base oil. Different emulsifiers, such as glycerol monostearate, soy lecithin and sucrose ester, and their respective amounts, were investigated. It was found that the addition of emulsifiers had a positive effect on water-absorbing capacity, air-absorbing capacity and viscosity of the oils. Glycerol monostearate was the preferred emulsifier for fluid shortening with a recommended addition of 1.5%. The effects of different diacylglycerol content on fluid shortening and their impact on sponge cake production was also investigated. The onset oxidation temperature of the oil could be increased from 253.21 ℃ for PO-TAG-based fluid shortening to 263.70 ℃ for PO-DAG85-based fluid shortening. And the increase in diacylglycerol content leading to a lower specific gravity of the batter, which was 1.06 g/mL, 1.02 g/mL and 0.98 g/mL prepared by PO-DAG, PO-DAG43 and PO-DAG85 shortening, respectively. The results showed that diacylglycerols can be used as base oils in fluid shortening to improve the crystal network and stability of fluid shortenings, thereby reducing the specific gravity of the batter and improving the structural properties of the cake. This will extend the potential applications of diacylglycerols and increase the variety of base oils available for fluid shortening preparation.展开更多
AIM:To report the myopia-controlling effect of repeated low-level red-light(RLRL)therapy in patients with Stickler syndrome(STL),an inherited collagenic disease typically presenting with early onset myopia.METHODS:Thr...AIM:To report the myopia-controlling effect of repeated low-level red-light(RLRL)therapy in patients with Stickler syndrome(STL),an inherited collagenic disease typically presenting with early onset myopia.METHODS:Three STL children,aged 3,7,and 11y,received RLRL therapy throughout the follow-up period of 17,3,and 6mo,respectively after exclusion of fundus anomalies.Data on best-corrected visual acuity(BCVA),intraocular pressure,cycloplegic subjective refraction,ocular biometrics,scanning laser ophthalmoscope,optical coherence tomography,genetic testing,systemic disease history,and family history were recorded.RESULTS:At the initiation of the RLRL therapy,the spherical equivalent(SE)of 6 eyes from 3 patients ranged from-3.75 to-20.38 D,axial length(AL)were from 23.88 to 30.68 mm,and BCVA were from 0.4 to 1.0(decimal notation).Myopia progression of all six eyes slowed down after RLRL therapy.AL in five out of the six eyes shortened-0.07 to-0.63 mm.No side effects were observed.CONCLUSION:Three cases of STL whose progression of myopic shift and AL elongation are successfully reduced and even reversed after RLRL therapy.展开更多
Maturation of the 3′end of almost all eukaryotic messenger RNAs(m RNAs)requires cleavage and polyadenylation.Most mammalian m RNAs are polyadenylated at different sites within the last exon,generating alternative pol...Maturation of the 3′end of almost all eukaryotic messenger RNAs(m RNAs)requires cleavage and polyadenylation.Most mammalian m RNAs are polyadenylated at different sites within the last exon,generating alternative polyadenylation(APA)isoforms that have the same coding region but distinct 3′untranslated regions(UTRs).The 3′UTR contains motifs that regulate m RNA metabolism;thus,changing the 3′UTR length via APA can significantly affect gene expression.Endochondral ossification is a central process in bone healing,but the impact of APA on gene expression during this process is unknown.Here,we report the widespread occurrence of APA,which impacts multiple pathways that are known to participate in bone healing.Importantly,the progression of endochondral ossification involves global 3′UTR shortening,which is coupled with an increased abundance of shortened transcripts relative to other transcripts;these results highlight the role of APA in promoting gene expression during endochondral bone formation.Our mechanistic studies of transcripts that undergo APA in the fracture callus revealed an intricate regulatory network in which APA enhances the expression of the collagen,type I,alpha 1(Col1a1)and Col1a2 genes,which encode the 2 subunits of the abundantly expressed protein collagen 1.APA exerts this effect by shortening the 3′UTRs of the Col1a1 and Col1a2 m RNAs,thus removing the binding sites of mi R-29a-3p,which would otherwise strongly promote the degradation of both transcripts.Taken together,our study is the first to characterize the crucial roles of APA in regulating the 3′UTR landscape and modulating gene expression during fracture healing.展开更多
BACKGROUND Although metaphyseal ulnar shortening osteotomy(MUSO)is safer for the treatment of ulnar impaction syndrome(UIS)than diaphyseal ulnar shortening osteotomy(DUSO),DUSO is widely used for UIS treatment.AIM To ...BACKGROUND Although metaphyseal ulnar shortening osteotomy(MUSO)is safer for the treatment of ulnar impaction syndrome(UIS)than diaphyseal ulnar shortening osteotomy(DUSO),DUSO is widely used for UIS treatment.AIM To evaluate the effectiveness of DUSO and MUSO for UIS treatment and determine the factors that should be considered when choosing surgical treatment for UIS.METHODS Articles comparing the effectiveness of DUSO and MUSO for UIS treatment were systematically retrieved from MEDLINE(Ovid),PubMed,EMBASE,and Cochrane Library.The demography,incidence of complications,secondary operation rate,postoperative DASH score,wrist pain on the visual analogue scale,and grip strength improvement were also evaluated.In addition,the correlation between the improvement of grip strength and the shortening of osteotomy length of ulna was analyzed.The outcome of the patient was discontinuous,and the odds ratio,risk ratio(RR),and 95%CI were calculated and analyzed via RevMan5.3 software.RESULTS Six studies,including 83 patients receiving MUSO(experimental group)and 112 patients receiving DUSO(control group),were included in the meta-analysis.The second operation rate was significantly higher after DUSO than after MUSO.The DASH scores were slightly lower in the MUSO group than in the DUSO group.The patients receiving MUSO had slightly better pain relief effect than patients receiving DUSO.However,the incidence of complications and improvement of grip strength were not significantly different between the two groups.CONCLUSION Although DUSO and MUSO provide similar effects for UIS,MUSO is associated with a lower secondary operation rate,slightly lower postoperative DASH scores and slightly better pain relief effect than DUSO,indicating that MUSO can effectively be used for UIS treatment.展开更多
According to the principle of minimizing total cost, the three-echelon optimized medical inventory model with stochastic lead-time and two-echelon optimized medicine inventory model with fixed lead-time are establishe...According to the principle of minimizing total cost, the three-echelon optimized medical inventory model with stochastic lead-time and two-echelon optimized medicine inventory model with fixed lead-time are established. The relationship between lead-time and inventory cost is studied by Matlab software. It shows that the variety of lead-time has an important effect on medicine inventory systems. Numerical simulation and sensitivity analysis of two models are presented by Lingo software. Based on analysis, it is concluded that the two-echelon model with lead-time results in inventory cost savings, and keeps the quality of care as reflected in service levels when compared with the three-echelon network structure.展开更多
Shortening is one of important word formations which demands attentions of both teachers and students. The paper first briefly introduces shortening words in English into clipped words, initialisms, acronyms and blend...Shortening is one of important word formations which demands attentions of both teachers and students. The paper first briefly introduces shortening words in English into clipped words, initialisms, acronyms and blends,and then it mainly explores the reasons why shortening words appear and become popular.展开更多
Strong deformed sediments investigated in the Hoh Xil basin may contain detailed records for early Tertiary crustal shortening in northern Tibet (Fig.1A). Sedimentary sequences in the basin consist of the Fenghuoshan ...Strong deformed sediments investigated in the Hoh Xil basin may contain detailed records for early Tertiary crustal shortening in northern Tibet (Fig.1A). Sedimentary sequences in the basin consist of the Fenghuoshan Group, the Yaxicuo Group, and the early Miocene Wudaoliang Group from lower to upper. Magnetostratigraphic research has indicated the Eocene to early Oligocene ages for the Fenghuoshan and Yaxicuo Groups (Liu, et al., 2000). Total 29 lithological sections with 20487 7m thick were measured spread all over the 101000km\+2 Hoh Xil basin, the largest Tertiary sedimentary basin in the hinterland of the Tibetan plateau, to reveal the prototype basin and its evolution processes. They include 17 sections with 14925 3m thick of the Fenghuoshan Group, 8 sections with 4273 5m thick of the Yaxicuo Group, and 4 sections with 1284 9m thick of the Wudaoliang Group.展开更多
Geological studies indicate that Qinghai\|Tibet plateau crust has shortened at least 2500km and the thickness was increased to 60~70km in the past 45Ma. Different researchers advocate different views to explain the s...Geological studies indicate that Qinghai\|Tibet plateau crust has shortened at least 2500km and the thickness was increased to 60~70km in the past 45Ma. Different researchers advocate different views to explain the shortening according to their studies.( Tapponnier,1977;Chang et al,1986;England et al,1986;Murphy,1997;Y.Pan,1999),however it is still unresolved on how much shortening in upper crustal especially in Qiangtang terrain.Qiangtang terrain is located in the center of Qinghai\|Tibet plateau, the tectonic deformation has been resulted from intracontinental convergence and collision of India plate with Eurasian plate.The deformation style of Qiangtang terrain shows east\|west\|trending folds and thrusts which formed in the shallow tectonic level during collisional\|intracontinental period. The folds type is characterized by nonpenetrative\|foliation parallel fold, the hinges have the same trend with the thrusts. These traits are favourable for restoring the balanced cross\|section and measuring the shortening. The balanced reconstruction is based on line balancing on three different stratigraphic sections (A,B and C)across the Northern Qiangtang basin in the area between 85°E and 87°E.The sections are all north\|south\|trending in accordance with the moving direction of thrusts.展开更多
Finite strain patterns of rocks The structural styles and crustal shortening in the northern margin of Qinghai—Tibet plateau are examined by systematic finite strain measurements. The finite strain patterns in this a...Finite strain patterns of rocks The structural styles and crustal shortening in the northern margin of Qinghai—Tibet plateau are examined by systematic finite strain measurements. The finite strain patterns in this area are of following characteristics:① The orientation of & principal axes of strain ellipsoid varies regularly in regard to different tectonic locations. In fact, most of the measured X axes are parallel to the regional structure lines, striking east\|west or approximately east\|west with some X axes trending northeast\|southwest. The measured Z\|axes are approximately at right angle to the regional structure lines, trending north\|northeast or north\|northwest.② The Flinn parameter k is higher in the northern and southern margins of the basin than that in the basin center, indicating that the margins of basin experienced extensional strain and the middle of basin undergo strain.③ Rocks of different age possess different strain state and show k value of 1~2 for Tertiary rocks, 3~4 for Jurassic—Cretaceous rocks. The k value of the basement rocks is the highest of all.展开更多
The M-BCJR algorithm based on the Ungerboeck observation model is a recent study to reduce the computational complexity for faster-than-Nyquist(FTN)signaling[1].In this paper,we propose a method that can further reduc...The M-BCJR algorithm based on the Ungerboeck observation model is a recent study to reduce the computational complexity for faster-than-Nyquist(FTN)signaling[1].In this paper,we propose a method that can further reduce the complexity with the approximately same or better bit error rate(BER)performance compared to[1].The information rate(IR)loss for the proposed method is less than 1%compared to the true achievable IR(AIR).The proposed improvement is mainly by introducing channel shortening(CS)before the M-BCJR equalizer.In our proposal,the Ungerboeck M-BCJR algorithm and CS can work together to defeat severe inter-symbol interference(ISI)introduced by FTN signaling.The ISI length for the M-BCJR algorithm with CS is optimized based on the criterion of the IR maximization.For the two cases=0.5 and=0.35,compared to Ungerboeck M-BCJR without CS benchmark[1],the computational complexities of Ungerboeck M-BCJR with CS are reduced by 75%.Moreover,for the case=0.35,the BER performance of Ungerboeck M-BCJR with CS outperforms that of the conventional M-BCJR in[1]at the low signal to noise ratio region.展开更多
It seems to be progressively recognized that the stress of the India-Asia convergent front can be transferred rapidly through the southern and central Tibetan lithosphere to the northern Tibet, hence leading to the cr...It seems to be progressively recognized that the stress of the India-Asia convergent front can be transferred rapidly through the southern and central Tibetan lithosphere to the northern Tibet, hence leading to the crustal thickening deformation there during or immediately after the onset of the India-Asia collision(ca.55 Ma).This study focuses on the late Cenozoic deformation and tectonic uplift of the northern Tibet and Tian Shan area.Detailed compilations of a variety of proxy data from sediments and bedrocks suggest that the northern Tibet and Tian Shan area underwent one stage of approximately synchronous widespread contractile deformation since 25–20 Ma, which seemed to decrease at circa 18 Ma as revealed by low-temperature thermochronological data.The latest Oligocene-early Miocene was also significant basin-forming episodes when many intermontane subbasins began to receive syntectonic sedimentation in the northeastern Tibet.Subsequently, the other phase of compressional deformation began to encroach more widely into the northern Tibet and Tian Shan area in episodic steps or continuously from 16–12 Ma to present.展开更多
Based on the continuous strain data recorded in Xinjiang since 1985, we discuss the mechanisms of Tianshan' s uplift and Tarim basin' s clockwise rotation. The results indicate : 1 ) The principal - compression di...Based on the continuous strain data recorded in Xinjiang since 1985, we discuss the mechanisms of Tianshan' s uplift and Tarim basin' s clockwise rotation. The results indicate : 1 ) The principal - compression directions in Tianshan are nearly NS, and their intersection angles with regional structures and mountains are nearly perpendicular, which is in accordance with Tianshan' s uplift and crustal shortening. 2)The principal compressions around Tarim basin tend to facilitate the regional faults' left-lateral strike-slip movements and the basin' s clockwise rotation. These phenomena of uplift/shortening and rotation are fundamentally the re- suits of India plate' s northward push on Euro-Asia plate, and the associated Pamir arc ' s rapid northward movement and regional blocks' interaction.展开更多
A theoretical analysis of the rheological fluid flow due to peristalsis is studied. We have applied the classical lubrication theory to predict the near physiological behavior of the intestinal segment, mixing and tra...A theoretical analysis of the rheological fluid flow due to peristalsis is studied. We have applied the classical lubrication theory to predict the near physiological behavior of the intestinal segment, mixing and transport. A parametric study involving the changes in local longitudinal shortening (LLS) magnitude, LLS spacing, fluid viscosity, wavelength of the wave, and occlusion of lumen caused by the wave provided insights into the dynamics of the peristalsis flow of a non-Newtonian fluid. LLS appear to have little significance in modulating the flow patterns that are caused by circular contraction alone. Results also indicate that there exists trade-off between the power requirement for peristalsis at a certain occlusion against the percentage LLS. LLS appear to be more advantageous to perform the peristalsis activity at higher occlusion than lower occlusion. Having mucosal folds in the inner lining of the intestine allows for one more advantage of slowing the transit due to increased friction factor and increase in time for absorption of the nutrients.展开更多
Faster-than-Nyquist(FTN)signaling can improve the spectrum efficiency(SE)of the transmission system.In this paper,we propose a coded modulation FTN(CM-FTN)transmission scheme with precoder and channel shortening(CS)op...Faster-than-Nyquist(FTN)signaling can improve the spectrum efficiency(SE)of the transmission system.In this paper,we propose a coded modulation FTN(CM-FTN)transmission scheme with precoder and channel shortening(CS)optimization to improve bit error rate(BER)performance and reduce the complexity of FTN equalizer.In our proposal,the information rate(IR)or spectral efficiency(SE)is employed and verified as a better performance metric for CM-FTN than the minimum Euclidian distance(MED).The precoder of CM-FTN is optimized for maximizing the IR criterion using the bare-bones particle swarm optimization(BB-PSO)algorithm.Further,a three-carrier CM-FTN system model is used to capture the broadening effect of precoder.Also targeting for the IR maximization,the inter-symbol interference(ISI)length for CS is optimized to reduce the receiver complexity without performance loss.Simulation results demonstrate that our method has a 0.6dB precoding gain compared with the nonprecoding scheme and a maximum of 87.5%of the complexity of FTN equalizer is reduced without BER loss.展开更多
AIM:To study the angle between the circular smooth muscle(CSM) and longitudinal smooth muscle(LSM) fibers in the distal esophagus.METHODS:In order to identify possible mechanisms for greater shortening in the distal c...AIM:To study the angle between the circular smooth muscle(CSM) and longitudinal smooth muscle(LSM) fibers in the distal esophagus.METHODS:In order to identify possible mechanisms for greater shortening in the distal compared to proximal esophagus during peristalsis,the angles between the LSM and CSM layers were measured in 9 cadavers.The outer longitudinal layer of the muscularis propria was exposed after stripping the outer serosa.The inner circular layer of the muscularis propria was then revealed after dissection of the esophageal mucosa and the underlying muscularis mucosa.Photographs of each specimen were taken with half of the open esophagus folded back showing both the outer longitudinal and inner circular muscle layers.Angles were measured every one cm for 10 cm proximal to the squamocolumnar junction(SCJ) by two independent investigators.Two human esophagi were obtained from organ transplant donors and the angles between the circular and longitudinal smooth muscle layers were measured using micro-computed tomography(micro CT) and Image J software.RESULTS:All data are presented as mean ± SE.The CSM to LSM angle at the SCJ and 1 cm proximal to SCJ on the autopsy specimens was 69.3 ± 4.62 degrees vs 74.9 ± 3.09 degrees,P = 0.32.The CSM to LSM angle at SCJ were statistically significantly lower than at 2,3,4 and 5 cm proximal to the SCJ,69.3 ± 4.62 degrees vs 82.58 ± 1.34 degrees,84.04 ± 1.64 degrees,84.87 ± 1.04 degrees and 83.72 ± 1.42 degrees,P = 0.013,P = 0.008,P = 0.004,P = 0.009 respectively.The CSM to LSM angle at SCJ was also statistically significantly lower than the angles at 6,7 and 8 cm proximal to the SCJ,69.3 ± 4.62 degrees vs 80.18 ± 2.09 degrees,81.81 ± 1.75 degrees and 80.96 ± 2.04 degrees,P = 0.05,P = 0.02,P = 0.03 respectively.The CSM to LSM angle at 1 cm proximal to SCJ was statistically significantly lower than at 3,4 and 5 cm proximal to the SCJ,74.94 ± 3.09 degrees vs 84.04 ± 1.64 degrees,84.87 ± 1.04 degrees and 83.72 ± 1.42 degrees,P = 0.019,P = 0.008,P = 0.02 respectively.At 10 cm above SCJ the angle was 80.06 ± 2.13 degrees which is close to being perpendicular but less than 90 degrees.The CSM to LSM angles measured on virtual dissection of the esophagus and the stomach on micro CT at the SCJ and 1 cm proximal to the SCJ were 48.39 ± 0.72 degrees and 50.81 ± 1.59 degrees.Rather than the angle of the CSM and LSM being perpendicular in the esophagus we found an acute angulation between these two muscle groups throughout the lower 10 cm of the esophagus.CONCLUSION:The oblique angulation of the CSM may contribute to the significantly greater shortening of distal esophagus when compared to the mid and proximal esophagus during peristalsis.展开更多
The purpose of this study was to investigate the suitability of palm diacylglycerol (PDAG)-enriched formulations for bakery shortening. Three types of palm diacylglycerol olein (PDAGOL) at different degree of unsa...The purpose of this study was to investigate the suitability of palm diacylglycerol (PDAG)-enriched formulations for bakery shortening. Three types of palm diacylglycerol olein (PDAGOL) at different degree of unsaturation (PDAGOL1V56, PDAGOLIV62 and PDAGOLIV64) were used as main raw materials blended with palm stearin (PS). The blending compositions ranged from 30% to 70% of PDAGOLIV56/PS, PDAGOLIV62/PS and PDAGOLIV64/PS, respectively. The physicochemical properties of all binary blend systems were characterized for fatty acid composition (FAC), slip melting point (SMP) and solid fat content (SFC). The selected bakery shortening formulations were further characterised for polymorphic form of fat crystal and thermal behavior, using X-ray diffractometer (XRD) and differential scanning calorimetry (DSC). Bakery shortening enriched with diacylglycerol that were produced from 40DS56 (40% PDAGOLIV56/60% PS), 40DS62 (40% PDAGOL1V62/60% PS) and 40DS64 (40% PDAGOLIV64/60% PS) had 45%-50% unsaturated fatty acid and crystallized in β + β polymorphs; thus they were suitable for shortening system. Based on product's baking performance, it could be found that all Madeira cakes prepared from bakery shortening enriched with diacylglycerol had higher specific cake volume as compared to commercial shortening (CS). In customer acceptance test, Madeira cake made from 40DS56 shortening scored the highest rating for all sensory attributes, including overall customer acceptability. It had given an indication that 40DS56 shortening formulation was the most suitable fat blends to be used as bakery shortening.展开更多
It is one of hot issues in Tibetan research that is to study the mode,process and kinetics of the crustal shortening during Mesozoic-Cenozoic.In this paper, on the basis of systematic collection,analysis and research ...It is one of hot issues in Tibetan research that is to study the mode,process and kinetics of the crustal shortening during Mesozoic-Cenozoic.In this paper, on the basis of systematic collection,analysis and research of the existing data and results from Himalayas,Lhasa and Qiangtang terranes,we conducted the balanced cross-section study.In the north Qiangtang,the line-balanced cross-section展开更多
In Discrete Multi-Tone (DMT) modulation systems, the well-known technique to overcome the Inter-Carrier Interference (ICI)/Inter-Symbol Interference (ISI) caused by the inadequate Cyclic Prefix (CP) length is to use a...In Discrete Multi-Tone (DMT) modulation systems, the well-known technique to overcome the Inter-Carrier Interference (ICI)/Inter-Symbol Interference (ISI) caused by the inadequate Cyclic Prefix (CP) length is to use a Time-Domain Equalizer (TDE) at the receiver front-end. An algorithm used to calculate the coefficients of the optimal shortening Time Domain Equalizer (TDE) was given by Melsa. However, this algorithm requires that the length of the TDE must be smaller than or equal to the memory length of the target impulse response. This paper modifies this algorithm and makes it not only fit for calculating the coefficients of the TDE with arbitrary length, but also have a much less computational time.展开更多
As a part of INDEPTH 3/GEODEPTH geological surface investigations were carried out during two field campaigns in 1998 and 1999. The working area covers a roughly N\|S (30~36°N) tren ding, 200km wide belt through...As a part of INDEPTH 3/GEODEPTH geological surface investigations were carried out during two field campaigns in 1998 and 1999. The working area covers a roughly N\|S (30~36°N) tren ding, 200km wide belt through the Lhasa Terrane and Qiangtang Terrane at a longitude of 88~90°E. Field geology was focused on geological mapping, structural measurements, and extensive sampling for the purpose of fission track geochronology. Additionally a total number of 742 orientated palaeomagnetic samples were drilled at 73 sites. Most of the samples were taken in fine\|grained sediments of Cretaceous, Eocene, and Neogene age. Five sites were drilled in acid to intermediate volcanics.A first sequence of measurements has been applied on a set of specimen. Most of the chosen formations (>80%) have acquired stable remanences which are carried by hematite and magnetite. As an example for the characteristic demagnetising behaviour of fine\|grained probable Cretaceous sandstones see Fig.1a. The unblocking temperature of 650℃ allows to identify hematite as remanence carrier.. Although single sites show well\|defined mean directions (e.g. site 76B: α 95 =3 8; k =185 8) the distribution among several site means of one formation could scatter (Fig.1b). It has to be checked carefully if rotations of single crustal elements are responsible for this effect. There is evidence to assume the detected characteristic remanences to be primary—further analysis including fold tests will be performed after the data set has increased.展开更多
We use two simple methods to derive four important explicit graphical solutions of the curve shortening flow in the plane. They are well-known as the circle, hairclip, paperclip, and grim reaper solutions of the curve...We use two simple methods to derive four important explicit graphical solutions of the curve shortening flow in the plane. They are well-known as the circle, hairclip, paperclip, and grim reaper solutions of the curve shortening flow. By the methods, one can also see that the hairclip and the paperclip solutions both converge to the grim reaper solutions as t → -∞.展开更多
基金The Bureau of Science and Information of Guangzhou under grant 2024A04J3254the National Natural Science Foundation of China under grant 32272341the Department of Science and Technology of Guangdong Province under grant numbers 2022B0202010003。
文摘Fluid shortening is an important ingredient in the production of sponge cake. Peanut oil with 0, 43% and 85% of diacylglycerol content was used as the base oil. Different emulsifiers, such as glycerol monostearate, soy lecithin and sucrose ester, and their respective amounts, were investigated. It was found that the addition of emulsifiers had a positive effect on water-absorbing capacity, air-absorbing capacity and viscosity of the oils. Glycerol monostearate was the preferred emulsifier for fluid shortening with a recommended addition of 1.5%. The effects of different diacylglycerol content on fluid shortening and their impact on sponge cake production was also investigated. The onset oxidation temperature of the oil could be increased from 253.21 ℃ for PO-TAG-based fluid shortening to 263.70 ℃ for PO-DAG85-based fluid shortening. And the increase in diacylglycerol content leading to a lower specific gravity of the batter, which was 1.06 g/mL, 1.02 g/mL and 0.98 g/mL prepared by PO-DAG, PO-DAG43 and PO-DAG85 shortening, respectively. The results showed that diacylglycerols can be used as base oils in fluid shortening to improve the crystal network and stability of fluid shortenings, thereby reducing the specific gravity of the batter and improving the structural properties of the cake. This will extend the potential applications of diacylglycerols and increase the variety of base oils available for fluid shortening preparation.
文摘AIM:To report the myopia-controlling effect of repeated low-level red-light(RLRL)therapy in patients with Stickler syndrome(STL),an inherited collagenic disease typically presenting with early onset myopia.METHODS:Three STL children,aged 3,7,and 11y,received RLRL therapy throughout the follow-up period of 17,3,and 6mo,respectively after exclusion of fundus anomalies.Data on best-corrected visual acuity(BCVA),intraocular pressure,cycloplegic subjective refraction,ocular biometrics,scanning laser ophthalmoscope,optical coherence tomography,genetic testing,systemic disease history,and family history were recorded.RESULTS:At the initiation of the RLRL therapy,the spherical equivalent(SE)of 6 eyes from 3 patients ranged from-3.75 to-20.38 D,axial length(AL)were from 23.88 to 30.68 mm,and BCVA were from 0.4 to 1.0(decimal notation).Myopia progression of all six eyes slowed down after RLRL therapy.AL in five out of the six eyes shortened-0.07 to-0.63 mm.No side effects were observed.CONCLUSION:Three cases of STL whose progression of myopic shift and AL elongation are successfully reduced and even reversed after RLRL therapy.
基金National Institutes of Health(NIH)R01 DK121327 to R.A.E。
文摘Maturation of the 3′end of almost all eukaryotic messenger RNAs(m RNAs)requires cleavage and polyadenylation.Most mammalian m RNAs are polyadenylated at different sites within the last exon,generating alternative polyadenylation(APA)isoforms that have the same coding region but distinct 3′untranslated regions(UTRs).The 3′UTR contains motifs that regulate m RNA metabolism;thus,changing the 3′UTR length via APA can significantly affect gene expression.Endochondral ossification is a central process in bone healing,but the impact of APA on gene expression during this process is unknown.Here,we report the widespread occurrence of APA,which impacts multiple pathways that are known to participate in bone healing.Importantly,the progression of endochondral ossification involves global 3′UTR shortening,which is coupled with an increased abundance of shortened transcripts relative to other transcripts;these results highlight the role of APA in promoting gene expression during endochondral bone formation.Our mechanistic studies of transcripts that undergo APA in the fracture callus revealed an intricate regulatory network in which APA enhances the expression of the collagen,type I,alpha 1(Col1a1)and Col1a2 genes,which encode the 2 subunits of the abundantly expressed protein collagen 1.APA exerts this effect by shortening the 3′UTRs of the Col1a1 and Col1a2 m RNAs,thus removing the binding sites of mi R-29a-3p,which would otherwise strongly promote the degradation of both transcripts.Taken together,our study is the first to characterize the crucial roles of APA in regulating the 3′UTR landscape and modulating gene expression during fracture healing.
文摘BACKGROUND Although metaphyseal ulnar shortening osteotomy(MUSO)is safer for the treatment of ulnar impaction syndrome(UIS)than diaphyseal ulnar shortening osteotomy(DUSO),DUSO is widely used for UIS treatment.AIM To evaluate the effectiveness of DUSO and MUSO for UIS treatment and determine the factors that should be considered when choosing surgical treatment for UIS.METHODS Articles comparing the effectiveness of DUSO and MUSO for UIS treatment were systematically retrieved from MEDLINE(Ovid),PubMed,EMBASE,and Cochrane Library.The demography,incidence of complications,secondary operation rate,postoperative DASH score,wrist pain on the visual analogue scale,and grip strength improvement were also evaluated.In addition,the correlation between the improvement of grip strength and the shortening of osteotomy length of ulna was analyzed.The outcome of the patient was discontinuous,and the odds ratio,risk ratio(RR),and 95%CI were calculated and analyzed via RevMan5.3 software.RESULTS Six studies,including 83 patients receiving MUSO(experimental group)and 112 patients receiving DUSO(control group),were included in the meta-analysis.The second operation rate was significantly higher after DUSO than after MUSO.The DASH scores were slightly lower in the MUSO group than in the DUSO group.The patients receiving MUSO had slightly better pain relief effect than patients receiving DUSO.However,the incidence of complications and improvement of grip strength were not significantly different between the two groups.CONCLUSION Although DUSO and MUSO provide similar effects for UIS,MUSO is associated with a lower secondary operation rate,slightly lower postoperative DASH scores and slightly better pain relief effect than DUSO,indicating that MUSO can effectively be used for UIS treatment.
文摘According to the principle of minimizing total cost, the three-echelon optimized medical inventory model with stochastic lead-time and two-echelon optimized medicine inventory model with fixed lead-time are established. The relationship between lead-time and inventory cost is studied by Matlab software. It shows that the variety of lead-time has an important effect on medicine inventory systems. Numerical simulation and sensitivity analysis of two models are presented by Lingo software. Based on analysis, it is concluded that the two-echelon model with lead-time results in inventory cost savings, and keeps the quality of care as reflected in service levels when compared with the three-echelon network structure.
文摘Shortening is one of important word formations which demands attentions of both teachers and students. The paper first briefly introduces shortening words in English into clipped words, initialisms, acronyms and blends,and then it mainly explores the reasons why shortening words appear and become popular.
文摘Strong deformed sediments investigated in the Hoh Xil basin may contain detailed records for early Tertiary crustal shortening in northern Tibet (Fig.1A). Sedimentary sequences in the basin consist of the Fenghuoshan Group, the Yaxicuo Group, and the early Miocene Wudaoliang Group from lower to upper. Magnetostratigraphic research has indicated the Eocene to early Oligocene ages for the Fenghuoshan and Yaxicuo Groups (Liu, et al., 2000). Total 29 lithological sections with 20487 7m thick were measured spread all over the 101000km\+2 Hoh Xil basin, the largest Tertiary sedimentary basin in the hinterland of the Tibetan plateau, to reveal the prototype basin and its evolution processes. They include 17 sections with 14925 3m thick of the Fenghuoshan Group, 8 sections with 4273 5m thick of the Yaxicuo Group, and 4 sections with 1284 9m thick of the Wudaoliang Group.
文摘Geological studies indicate that Qinghai\|Tibet plateau crust has shortened at least 2500km and the thickness was increased to 60~70km in the past 45Ma. Different researchers advocate different views to explain the shortening according to their studies.( Tapponnier,1977;Chang et al,1986;England et al,1986;Murphy,1997;Y.Pan,1999),however it is still unresolved on how much shortening in upper crustal especially in Qiangtang terrain.Qiangtang terrain is located in the center of Qinghai\|Tibet plateau, the tectonic deformation has been resulted from intracontinental convergence and collision of India plate with Eurasian plate.The deformation style of Qiangtang terrain shows east\|west\|trending folds and thrusts which formed in the shallow tectonic level during collisional\|intracontinental period. The folds type is characterized by nonpenetrative\|foliation parallel fold, the hinges have the same trend with the thrusts. These traits are favourable for restoring the balanced cross\|section and measuring the shortening. The balanced reconstruction is based on line balancing on three different stratigraphic sections (A,B and C)across the Northern Qiangtang basin in the area between 85°E and 87°E.The sections are all north\|south\|trending in accordance with the moving direction of thrusts.
文摘Finite strain patterns of rocks The structural styles and crustal shortening in the northern margin of Qinghai—Tibet plateau are examined by systematic finite strain measurements. The finite strain patterns in this area are of following characteristics:① The orientation of & principal axes of strain ellipsoid varies regularly in regard to different tectonic locations. In fact, most of the measured X axes are parallel to the regional structure lines, striking east\|west or approximately east\|west with some X axes trending northeast\|southwest. The measured Z\|axes are approximately at right angle to the regional structure lines, trending north\|northeast or north\|northwest.② The Flinn parameter k is higher in the northern and southern margins of the basin than that in the basin center, indicating that the margins of basin experienced extensional strain and the middle of basin undergo strain.③ Rocks of different age possess different strain state and show k value of 1~2 for Tertiary rocks, 3~4 for Jurassic—Cretaceous rocks. The k value of the basement rocks is the highest of all.
基金This work was supported by National Natural Science Foundation of China(No.61961014).
文摘The M-BCJR algorithm based on the Ungerboeck observation model is a recent study to reduce the computational complexity for faster-than-Nyquist(FTN)signaling[1].In this paper,we propose a method that can further reduce the complexity with the approximately same or better bit error rate(BER)performance compared to[1].The information rate(IR)loss for the proposed method is less than 1%compared to the true achievable IR(AIR).The proposed improvement is mainly by introducing channel shortening(CS)before the M-BCJR equalizer.In our proposal,the Ungerboeck M-BCJR algorithm and CS can work together to defeat severe inter-symbol interference(ISI)introduced by FTN signaling.The ISI length for the M-BCJR algorithm with CS is optimized based on the criterion of the IR maximization.For the two cases=0.5 and=0.35,compared to Ungerboeck M-BCJR without CS benchmark[1],the computational complexities of Ungerboeck M-BCJR with CS are reduced by 75%.Moreover,for the case=0.35,the BER performance of Ungerboeck M-BCJR with CS outperforms that of the conventional M-BCJR in[1]at the low signal to noise ratio region.
基金granted by the National Natural Science Foundation of China (Grant No.41472187)the China Geological Survey project (Grant No.12120114022901, 12120115027001)
文摘It seems to be progressively recognized that the stress of the India-Asia convergent front can be transferred rapidly through the southern and central Tibetan lithosphere to the northern Tibet, hence leading to the crustal thickening deformation there during or immediately after the onset of the India-Asia collision(ca.55 Ma).This study focuses on the late Cenozoic deformation and tectonic uplift of the northern Tibet and Tian Shan area.Detailed compilations of a variety of proxy data from sediments and bedrocks suggest that the northern Tibet and Tian Shan area underwent one stage of approximately synchronous widespread contractile deformation since 25–20 Ma, which seemed to decrease at circa 18 Ma as revealed by low-temperature thermochronological data.The latest Oligocene-early Miocene was also significant basin-forming episodes when many intermontane subbasins began to receive syntectonic sedimentation in the northeastern Tibet.Subsequently, the other phase of compressional deformation began to encroach more widely into the northern Tibet and Tian Shan area in episodic steps or continuously from 16–12 Ma to present.
基金supported by the National Natural Science Foundation of China( 40864003,40562001)
文摘Based on the continuous strain data recorded in Xinjiang since 1985, we discuss the mechanisms of Tianshan' s uplift and Tarim basin' s clockwise rotation. The results indicate : 1 ) The principal - compression directions in Tianshan are nearly NS, and their intersection angles with regional structures and mountains are nearly perpendicular, which is in accordance with Tianshan' s uplift and crustal shortening. 2)The principal compressions around Tarim basin tend to facilitate the regional faults' left-lateral strike-slip movements and the basin' s clockwise rotation. These phenomena of uplift/shortening and rotation are fundamentally the re- suits of India plate' s northward push on Euro-Asia plate, and the associated Pamir arc ' s rapid northward movement and regional blocks' interaction.
文摘A theoretical analysis of the rheological fluid flow due to peristalsis is studied. We have applied the classical lubrication theory to predict the near physiological behavior of the intestinal segment, mixing and transport. A parametric study involving the changes in local longitudinal shortening (LLS) magnitude, LLS spacing, fluid viscosity, wavelength of the wave, and occlusion of lumen caused by the wave provided insights into the dynamics of the peristalsis flow of a non-Newtonian fluid. LLS appear to have little significance in modulating the flow patterns that are caused by circular contraction alone. Results also indicate that there exists trade-off between the power requirement for peristalsis at a certain occlusion against the percentage LLS. LLS appear to be more advantageous to perform the peristalsis activity at higher occlusion than lower occlusion. Having mucosal folds in the inner lining of the intestine allows for one more advantage of slowing the transit due to increased friction factor and increase in time for absorption of the nutrients.
基金This work was supported by National Natural Science Foundation of China(No.61961014).
文摘Faster-than-Nyquist(FTN)signaling can improve the spectrum efficiency(SE)of the transmission system.In this paper,we propose a coded modulation FTN(CM-FTN)transmission scheme with precoder and channel shortening(CS)optimization to improve bit error rate(BER)performance and reduce the complexity of FTN equalizer.In our proposal,the information rate(IR)or spectral efficiency(SE)is employed and verified as a better performance metric for CM-FTN than the minimum Euclidian distance(MED).The precoder of CM-FTN is optimized for maximizing the IR criterion using the bare-bones particle swarm optimization(BB-PSO)algorithm.Further,a three-carrier CM-FTN system model is used to capture the broadening effect of precoder.Also targeting for the IR maximization,the inter-symbol interference(ISI)length for CS is optimized to reduce the receiver complexity without performance loss.Simulation results demonstrate that our method has a 0.6dB precoding gain compared with the nonprecoding scheme and a maximum of 87.5%of the complexity of FTN equalizer is reduced without BER loss.
基金Supported by The National Institute of Diabetes and Digestive and Kidney Diseases,No. R01 DK079954,to Ruggieri MR and Miller LS
文摘AIM:To study the angle between the circular smooth muscle(CSM) and longitudinal smooth muscle(LSM) fibers in the distal esophagus.METHODS:In order to identify possible mechanisms for greater shortening in the distal compared to proximal esophagus during peristalsis,the angles between the LSM and CSM layers were measured in 9 cadavers.The outer longitudinal layer of the muscularis propria was exposed after stripping the outer serosa.The inner circular layer of the muscularis propria was then revealed after dissection of the esophageal mucosa and the underlying muscularis mucosa.Photographs of each specimen were taken with half of the open esophagus folded back showing both the outer longitudinal and inner circular muscle layers.Angles were measured every one cm for 10 cm proximal to the squamocolumnar junction(SCJ) by two independent investigators.Two human esophagi were obtained from organ transplant donors and the angles between the circular and longitudinal smooth muscle layers were measured using micro-computed tomography(micro CT) and Image J software.RESULTS:All data are presented as mean ± SE.The CSM to LSM angle at the SCJ and 1 cm proximal to SCJ on the autopsy specimens was 69.3 ± 4.62 degrees vs 74.9 ± 3.09 degrees,P = 0.32.The CSM to LSM angle at SCJ were statistically significantly lower than at 2,3,4 and 5 cm proximal to the SCJ,69.3 ± 4.62 degrees vs 82.58 ± 1.34 degrees,84.04 ± 1.64 degrees,84.87 ± 1.04 degrees and 83.72 ± 1.42 degrees,P = 0.013,P = 0.008,P = 0.004,P = 0.009 respectively.The CSM to LSM angle at SCJ was also statistically significantly lower than the angles at 6,7 and 8 cm proximal to the SCJ,69.3 ± 4.62 degrees vs 80.18 ± 2.09 degrees,81.81 ± 1.75 degrees and 80.96 ± 2.04 degrees,P = 0.05,P = 0.02,P = 0.03 respectively.The CSM to LSM angle at 1 cm proximal to SCJ was statistically significantly lower than at 3,4 and 5 cm proximal to the SCJ,74.94 ± 3.09 degrees vs 84.04 ± 1.64 degrees,84.87 ± 1.04 degrees and 83.72 ± 1.42 degrees,P = 0.019,P = 0.008,P = 0.02 respectively.At 10 cm above SCJ the angle was 80.06 ± 2.13 degrees which is close to being perpendicular but less than 90 degrees.The CSM to LSM angles measured on virtual dissection of the esophagus and the stomach on micro CT at the SCJ and 1 cm proximal to the SCJ were 48.39 ± 0.72 degrees and 50.81 ± 1.59 degrees.Rather than the angle of the CSM and LSM being perpendicular in the esophagus we found an acute angulation between these two muscle groups throughout the lower 10 cm of the esophagus.CONCLUSION:The oblique angulation of the CSM may contribute to the significantly greater shortening of distal esophagus when compared to the mid and proximal esophagus during peristalsis.
文摘The purpose of this study was to investigate the suitability of palm diacylglycerol (PDAG)-enriched formulations for bakery shortening. Three types of palm diacylglycerol olein (PDAGOL) at different degree of unsaturation (PDAGOL1V56, PDAGOLIV62 and PDAGOLIV64) were used as main raw materials blended with palm stearin (PS). The blending compositions ranged from 30% to 70% of PDAGOLIV56/PS, PDAGOLIV62/PS and PDAGOLIV64/PS, respectively. The physicochemical properties of all binary blend systems were characterized for fatty acid composition (FAC), slip melting point (SMP) and solid fat content (SFC). The selected bakery shortening formulations were further characterised for polymorphic form of fat crystal and thermal behavior, using X-ray diffractometer (XRD) and differential scanning calorimetry (DSC). Bakery shortening enriched with diacylglycerol that were produced from 40DS56 (40% PDAGOLIV56/60% PS), 40DS62 (40% PDAGOL1V62/60% PS) and 40DS64 (40% PDAGOLIV64/60% PS) had 45%-50% unsaturated fatty acid and crystallized in β + β polymorphs; thus they were suitable for shortening system. Based on product's baking performance, it could be found that all Madeira cakes prepared from bakery shortening enriched with diacylglycerol had higher specific cake volume as compared to commercial shortening (CS). In customer acceptance test, Madeira cake made from 40DS56 shortening scored the highest rating for all sensory attributes, including overall customer acceptability. It had given an indication that 40DS56 shortening formulation was the most suitable fat blends to be used as bakery shortening.
文摘It is one of hot issues in Tibetan research that is to study the mode,process and kinetics of the crustal shortening during Mesozoic-Cenozoic.In this paper, on the basis of systematic collection,analysis and research of the existing data and results from Himalayas,Lhasa and Qiangtang terranes,we conducted the balanced cross-section study.In the north Qiangtang,the line-balanced cross-section
文摘In Discrete Multi-Tone (DMT) modulation systems, the well-known technique to overcome the Inter-Carrier Interference (ICI)/Inter-Symbol Interference (ISI) caused by the inadequate Cyclic Prefix (CP) length is to use a Time-Domain Equalizer (TDE) at the receiver front-end. An algorithm used to calculate the coefficients of the optimal shortening Time Domain Equalizer (TDE) was given by Melsa. However, this algorithm requires that the length of the TDE must be smaller than or equal to the memory length of the target impulse response. This paper modifies this algorithm and makes it not only fit for calculating the coefficients of the TDE with arbitrary length, but also have a much less computational time.
文摘As a part of INDEPTH 3/GEODEPTH geological surface investigations were carried out during two field campaigns in 1998 and 1999. The working area covers a roughly N\|S (30~36°N) tren ding, 200km wide belt through the Lhasa Terrane and Qiangtang Terrane at a longitude of 88~90°E. Field geology was focused on geological mapping, structural measurements, and extensive sampling for the purpose of fission track geochronology. Additionally a total number of 742 orientated palaeomagnetic samples were drilled at 73 sites. Most of the samples were taken in fine\|grained sediments of Cretaceous, Eocene, and Neogene age. Five sites were drilled in acid to intermediate volcanics.A first sequence of measurements has been applied on a set of specimen. Most of the chosen formations (>80%) have acquired stable remanences which are carried by hematite and magnetite. As an example for the characteristic demagnetising behaviour of fine\|grained probable Cretaceous sandstones see Fig.1a. The unblocking temperature of 650℃ allows to identify hematite as remanence carrier.. Although single sites show well\|defined mean directions (e.g. site 76B: α 95 =3 8; k =185 8) the distribution among several site means of one formation could scatter (Fig.1b). It has to be checked carefully if rotations of single crustal elements are responsible for this effect. There is evidence to assume the detected characteristic remanences to be primary—further analysis including fold tests will be performed after the data set has increased.
基金supported by MoST of Taiwan under grant number 105-2115-M-007-013supported by NSF of Jiangsu Province(BK20161412)the Postdoctoral Science Foundation of China(2016T90399,2014M561542)
文摘We use two simple methods to derive four important explicit graphical solutions of the curve shortening flow in the plane. They are well-known as the circle, hairclip, paperclip, and grim reaper solutions of the curve shortening flow. By the methods, one can also see that the hairclip and the paperclip solutions both converge to the grim reaper solutions as t → -∞.