<strong>Background: </strong>High-prevalence disorders among children are attention-deficit/ hyperactivity disorder (ADHD) and lead exposure. The purpose of this study was to find out the relationship betw...<strong>Background: </strong>High-prevalence disorders among children are attention-deficit/ hyperactivity disorder (ADHD) and lead exposure. The purpose of this study was to find out the relationship between ADHD symptoms and hair lead levels and neurocognitive function among Mongolian children. <strong>Methods: </strong>This was the case study to investigate the relationship between hair lead and ADHD in Mongolian school kids. We conducted a pair-matching case-control study with 30 ADHD cases and 30 non ADHD controls for 7 - 12 years of age school children, based on the same age, and sex. Recruitment process was conducted from June 2018 to December 2019. The case and control study children were systematically selected by structured diagnostic interviews, including caregiver interviews based on the Diagnostic and Statistical Manual of Mental Disorders, 4th ed (DSM-IV). <strong>Results:</strong> The average level of hair lead of the ADHD group was 1.45 ± 2.93 ppm and the control group’s lead level was 0.7 ± 1.59 ppm. We found ADHD-Combined (ADHD-C) patients showed the highest lead levels (p < 0.05). Hair lead levels were positively linked with the severity of ADHD symptoms, negatively linked with the Full-Scale Emotional Intelligence Quotient, but positively correlated with inattention and hyperactivity/impulsivity symptoms (p < 0.05). A statistically significant difference was discovered regarding the lead levels between the study and the control groups with significantly increased risks among boys and children whose mother had preeclampsia during the pregnancy period. Spearman’s correlation coefficient showed a notable negative connection between children’s hair lead levels with ADHD-Hyperactive (ADHD-H), and EQ (Emotional Quotient) level of children (<span style="white-space:nowrap;">−</span>0.329 and <span style="white-space:nowrap;">−</span>0.242, for original and log10 transformed, p < 0.001). The lead was linked with vulnerability to ADHD and symptom severity among those school-age children. <strong>Conclusions:</strong> The child hair lead exposure is one of the risk factors of the development of ADHD and decreasing FSIQ (Full Scale Intelligent Quotient) and EQ level of children and linked with susceptibility to ADHD and symptom severity in school-age children.展开更多
Over the past decades, there were questions often asked： What is education？ What is it purpose in the world whether it helps an individual or not to understand himself and connect his views with existing beliefs and...Over the past decades, there were questions often asked： What is education？ What is it purpose in the world whether it helps an individual or not to understand himself and connect his views with existing beliefs and critical thinking about education to deal with daily practical challenges enable in a new way. The founder of instrumentalism philosophical school, John Dewey remarks that knowledge is practical instrument that purpose must be to solve all problems that a person encounters during his/her lifetime. According to instrumentalism theoretical concepts, theories are instruments by means of that relationship with surrounding world is established （communication becomes possibleS. Representatives of traditional epistemology make distinct difference between ＂world＂ and ＂mind＂. In accordance with Dewey＇s genetic epistemology mind, constitutes the result of living being-environment relationship as the universe is defined by our mind and the development of a human＇s knowledge is adaptive response to the environment.展开更多
文摘<strong>Background: </strong>High-prevalence disorders among children are attention-deficit/ hyperactivity disorder (ADHD) and lead exposure. The purpose of this study was to find out the relationship between ADHD symptoms and hair lead levels and neurocognitive function among Mongolian children. <strong>Methods: </strong>This was the case study to investigate the relationship between hair lead and ADHD in Mongolian school kids. We conducted a pair-matching case-control study with 30 ADHD cases and 30 non ADHD controls for 7 - 12 years of age school children, based on the same age, and sex. Recruitment process was conducted from June 2018 to December 2019. The case and control study children were systematically selected by structured diagnostic interviews, including caregiver interviews based on the Diagnostic and Statistical Manual of Mental Disorders, 4th ed (DSM-IV). <strong>Results:</strong> The average level of hair lead of the ADHD group was 1.45 ± 2.93 ppm and the control group’s lead level was 0.7 ± 1.59 ppm. We found ADHD-Combined (ADHD-C) patients showed the highest lead levels (p < 0.05). Hair lead levels were positively linked with the severity of ADHD symptoms, negatively linked with the Full-Scale Emotional Intelligence Quotient, but positively correlated with inattention and hyperactivity/impulsivity symptoms (p < 0.05). A statistically significant difference was discovered regarding the lead levels between the study and the control groups with significantly increased risks among boys and children whose mother had preeclampsia during the pregnancy period. Spearman’s correlation coefficient showed a notable negative connection between children’s hair lead levels with ADHD-Hyperactive (ADHD-H), and EQ (Emotional Quotient) level of children (<span style="white-space:nowrap;">−</span>0.329 and <span style="white-space:nowrap;">−</span>0.242, for original and log10 transformed, p < 0.001). The lead was linked with vulnerability to ADHD and symptom severity among those school-age children. <strong>Conclusions:</strong> The child hair lead exposure is one of the risk factors of the development of ADHD and decreasing FSIQ (Full Scale Intelligent Quotient) and EQ level of children and linked with susceptibility to ADHD and symptom severity in school-age children.
文摘Over the past decades, there were questions often asked： What is education？ What is it purpose in the world whether it helps an individual or not to understand himself and connect his views with existing beliefs and critical thinking about education to deal with daily practical challenges enable in a new way. The founder of instrumentalism philosophical school, John Dewey remarks that knowledge is practical instrument that purpose must be to solve all problems that a person encounters during his/her lifetime. According to instrumentalism theoretical concepts, theories are instruments by means of that relationship with surrounding world is established （communication becomes possibleS. Representatives of traditional epistemology make distinct difference between ＂world＂ and ＂mind＂. In accordance with Dewey＇s genetic epistemology mind, constitutes the result of living being-environment relationship as the universe is defined by our mind and the development of a human＇s knowledge is adaptive response to the environment.
