During a 12-year period, 44 patients were surgically treated for stage- Ⅲ peripheral squamous cell car-cinoma of the right upper lobe. The mean time from the discovery of the shadow in the right upper lobe tothe conf...During a 12-year period, 44 patients were surgically treated for stage- Ⅲ peripheral squamous cell car-cinoma of the right upper lobe. The mean time from the discovery of the shadow in the right upper lobe tothe confirmation of the diagnosis was 2 months. All patients underwent the resection of the right upperlobe with the dissection of the right mediastinal lymph nodes, among them, 4 patients had sleeve lobectomy of the right upper lobe. P-TNM staging: 23 cases were in stage- Ⅲ a, 21 cases in stage- Ⅲ b. The fre-quency of the postoperative complications was 20- 4 % (9/44 cases). The 1-year survival rate of all patientswas 61 % (27/44 cases). None of stage - Ⅲ b patients lived longer than 3 years. The postoperative 3-and 5-year survival rates of stage- Ⅲ a cases were 65. 2 % (15/23cases) and 21. 7 % (5/23 cases) respectively. Inthis article, the patients clinical features, the causes of delayed-diagnosis, the operative and postoperativemanagement were discussed. We suggest that the stage- Ⅲ a patients should be given surgical treatment,whereas, for the patients of stage- Ⅲ b, palliative operation was given just for the purpose of reliving thesymptoms.展开更多
BACKGROUND Squamous cell carcinoma(SCC)of the liver is rare,and is more commonly found in the skin,rectum,cervical or inguinal lymph nodes.CASE SUMMARY A 73-year-old man had been experiencing right upper quadrant disc...BACKGROUND Squamous cell carcinoma(SCC)of the liver is rare,and is more commonly found in the skin,rectum,cervical or inguinal lymph nodes.CASE SUMMARY A 73-year-old man had been experiencing right upper quadrant discomfort for some weeks.He had a 50-year history of smoking and drinking.On average,he smoked 20 cigarettes and consumed 200 galcoholdaily.He didn’t have a history of hepatitis or surgery.Fever,vomiting,jaundice,dysuria,chills,and abdominal distention were not observed at the time of admission.Tenderness in the right upper quadrant was found on physical examination,but there was no palpable abdominal mass.No obvious abnormalities in laboratory tests and tumor markers were found.The plasma retention rate of indocyanine green(ICG)at 15 min was 1.35%.Subsequent abdominal ultrasonography showed a mixed echoic mass approximately 3.8 cm diameter in the left caudate lobe of the liver.Abdominal computed tomography confirmed a 3.0 cm×3.5 cm irregular mass with inhomogeneous density and moderate delayed enhancement in the left caudate lobe of the liver.Laparoscopic left caudate lobectomy was performed to remove the liver mass.Intra-operative findings confirmed a non-cirrhotic liver,with a 3 cm×3.5 cm white tumor mass in the left caudate lobe with no tumor rupture and no hemoperitoneum.The resection margin was 1.0 cm in width.CONCLUSION We describe the first case of SCC in the left caudate lobe of the liver,which was successfully treated by surgical resection and postoperative immunotherapy.No tumor recurrence was observed during the 8-mo follow-up.展开更多
文摘During a 12-year period, 44 patients were surgically treated for stage- Ⅲ peripheral squamous cell car-cinoma of the right upper lobe. The mean time from the discovery of the shadow in the right upper lobe tothe confirmation of the diagnosis was 2 months. All patients underwent the resection of the right upperlobe with the dissection of the right mediastinal lymph nodes, among them, 4 patients had sleeve lobectomy of the right upper lobe. P-TNM staging: 23 cases were in stage- Ⅲ a, 21 cases in stage- Ⅲ b. The fre-quency of the postoperative complications was 20- 4 % (9/44 cases). The 1-year survival rate of all patientswas 61 % (27/44 cases). None of stage - Ⅲ b patients lived longer than 3 years. The postoperative 3-and 5-year survival rates of stage- Ⅲ a cases were 65. 2 % (15/23cases) and 21. 7 % (5/23 cases) respectively. Inthis article, the patients clinical features, the causes of delayed-diagnosis, the operative and postoperativemanagement were discussed. We suggest that the stage- Ⅲ a patients should be given surgical treatment,whereas, for the patients of stage- Ⅲ b, palliative operation was given just for the purpose of reliving thesymptoms.
文摘BACKGROUND Squamous cell carcinoma(SCC)of the liver is rare,and is more commonly found in the skin,rectum,cervical or inguinal lymph nodes.CASE SUMMARY A 73-year-old man had been experiencing right upper quadrant discomfort for some weeks.He had a 50-year history of smoking and drinking.On average,he smoked 20 cigarettes and consumed 200 galcoholdaily.He didn’t have a history of hepatitis or surgery.Fever,vomiting,jaundice,dysuria,chills,and abdominal distention were not observed at the time of admission.Tenderness in the right upper quadrant was found on physical examination,but there was no palpable abdominal mass.No obvious abnormalities in laboratory tests and tumor markers were found.The plasma retention rate of indocyanine green(ICG)at 15 min was 1.35%.Subsequent abdominal ultrasonography showed a mixed echoic mass approximately 3.8 cm diameter in the left caudate lobe of the liver.Abdominal computed tomography confirmed a 3.0 cm×3.5 cm irregular mass with inhomogeneous density and moderate delayed enhancement in the left caudate lobe of the liver.Laparoscopic left caudate lobectomy was performed to remove the liver mass.Intra-operative findings confirmed a non-cirrhotic liver,with a 3 cm×3.5 cm white tumor mass in the left caudate lobe with no tumor rupture and no hemoperitoneum.The resection margin was 1.0 cm in width.CONCLUSION We describe the first case of SCC in the left caudate lobe of the liver,which was successfully treated by surgical resection and postoperative immunotherapy.No tumor recurrence was observed during the 8-mo follow-up.