Self‑Healing Dynamic Hydrogel Microparticles with Structural Color for Wound Management

Chronic diabetic wounds confront a significant medical challenge because of increasing prevalence and difficult-healing circumstances.It is vital to develop multifunctional hydrogel dressings,with well-designed morphology and structure to enhance flexibility and effectiveness in wound management.To achieve these,we propose a self-healing hydrogel dressing based on structural color microspheres for wound management.The microsphere comprised a photothermal-responsive inverse opal framework,which was constructed by hyaluronic acid methacryloyl,silk fibroin methacryloyl and black phosphorus quantum dots(BPQDs),and was further re-filled with a dynamic hydrogel.The dynamic hydrogel filler was formed by Knoevenagel condensation reaction between cyanoacetate and benzaldehyde-functionalized dextran(DEX-CA and DEX-BA).Notably,the composite microspheres can be applied arbitrarily,and they can adhere together upon near-infrared irradiation by leveraging the BPQDs-mediated photothermal effect and the thermoreversible stiffness change of dynamic hydrogel.Additionally,eumenitin and vascular endothelial growth factor were co-loaded in the microspheres and their release behavior can be regulated by the same mechanism.Moreover,effective monitoring of the drug release process can be achieved through visual color variations.The microsphere system has demonstrated desired capabilities of controllable drug release and efficient wound management.These characteristics suggest broad prospects for the proposed composite microspheres in clinical applications.

Highly Thermally Conductive and Structurally Ultra‑Stable Graphitic Films with Seamless Heterointerfaces for Extreme Thermal Management

Highly thermally conductive graphitic film(GF)materials have become a competitive solution for the thermal management of high-power electronic devices.However,their catastrophic structural failure under extreme alternating thermal/cold shock poses a significant challenge to reliability and safety.Here,we present the first investigation into the structural failure mechanism of GF during cyclic liquid nitrogen shocks(LNS),which reveals a bubbling process characterized by“permeation-diffusion-deformation”phenomenon.To overcome this long-standing structural weakness,a novel metal-nanoarmor strategy is proposed to construct a Cu-modified graphitic film(GF@Cu)with seamless heterointerface.This well-designed interface ensures superior structural stability for GF@Cu after hundreds of LNS cycles from 77 to 300 K.Moreover,GF@Cu maintains high thermal conductivity up to 1088 W m^(−1)K^(−1)with degradation of less than 5%even after 150 LNS cycles,superior to that of pure GF(50%degradation).Our work not only offers an opportunity to improve the robustness of graphitic films by the rational structural design but also facilitates the applications of thermally conductive carbon-based materials for future extreme thermal management in complex aerospace electronics.

Floristic Composition, Population Structure, and Recruitment Status of Plant Species: A Case Study of Farmer-Managed Natural Regeneration Practices in Arid and Semi-Arid Lands in Kenya

The technique of Farmer Managed Natural Regeneration (FMNR) is being promoted as a cost-effective approach for restoring degraded arable dry lands. Its effectiveness has been observed in many countries across the globe, where it is a traditional practice, and is now being encouraged across the African continent. This study aimed to evaluate the impact of FMNR on floristic Composition, Vegetation Structure, and Regeneration Status of woody Plant Species in the severely degraded Central Rift, Kenya. The study systematically assessed how FMNR influenced species composition, vegetation structure and regeneration status from two sample plots involved in FMNR practices. Transect lines and quadrats methods were utilized to collect data, specifically regarding the floristic composition, vegetation structure, and regeneration status of woody plant species. Quadrats and sub-quadrats of varying sizes (10 m by 10 m, 5 m by 5 m, and 1 m by 1 m) were nested along the transect lines for data collection. Furthermore, measurements of tree growth and development, including root collar diameter, diameter at breast height (D130) and heights within the study blocks, were taken. The data was then analyzed using R-software. Results showed a marked progressive increase in numbers of trees, saplings, seedlings, shrubs and herbs in all FMNR sites and reductions in all non-FMNR sites. The study advocates for widespread promotion of the FMNR practice both as an environmental conservation and restoration strategy.

Effects of three-dimensional quality assessment nursing intervention on efficacy and disease management of patients undergoing esophageal cancer surgery

BACKGROUND Esophageal cancer is one of the most common malignant tumors.The three-dimensional quality structure model is a quality assessment theory that includes three dimensions:Structure,process,and results.AIM To investigate the effects of nursing interventions with three-dimensional quality assessment on the efficacy and disease management ability of patients undergoing esophageal cancer surgery.METHODS In this prospective study,the control group received routine nursing,and the intervention group additionally received a three-dimensional quality assessment intervention based on the above routine care.Self-efficacy and patient disease management abilities were evaluated using the General Self-Efficacy Scale(GSES)and Exercise of Self-Care Agency scale,respectively.IBM SPSS Statistics for Windows,version 17.0,was used for the data processing.RESULTS This study recruited 112 patients who were assigned to the control and experi-mental groups(n=56 per group).Before the intervention,there was no significant difference in GSES scores between the two groups(P>0.05).After the inter-vention,the GSES scores of both groups increased,with the experimental group showing higher values(P<0.05).At the time of discharge and three months after discharge,the scores for positive attitudes,self-stress reduction,and total score of health promotion in the experimental group were higher than those in the control group(P<0.05).CONCLUSION The implementation of a three-dimensional quality structure model for postoperative patients with esophageal cancer can effectively improve their self-management ability and self-efficacy of postoperative patients.

Multi-objective Optimization Design of Wing Structure with the Model Management Framework

Evolutionary algorithm is time-consuming because of the large number of evolutions and much times of finite element analysis, when it is used to optimize the wing structure of a certain high altitude long endurance unmanned aviation vehicle（UAV）. In order to improve efficiency it is proposed to construct a model management framework to perform the multi-objective optimization design of wing structure. The sufficient accurate approximation models of objective and constraint functions in the wing structure optimization model are built when using the model management framework, therefore in the evolutionary algorithm a number of finite element analyses can he avoided and the satisfactory multi-objective optimization results of the wing structure of the high altitude long endurance UAV are obtained.

WJD 5^(th) Anniversary Special Issues(2): Type 2 diabetes Structured SMBG in early management of T2DM: Contributions from the St Carlos study

Diabetes mellitus type 2(T2DM)is a global pandemic that will affect 300 million people in the next decade.It has been shown that early and aggressive treatment of T2DM from the onset decreases complications,and the patient’s active role is necessary to achieve better glycemic control.In order to achieve glycemic control targets,an active attitude in patients is needed,and selfmonitoring of blood glucose(SMBG)plays a significant role.Nowadays,SMBG has become an important component of modern therapy for diabetes mellitus,and is even more useful if it is performed in a structured way.SMBG aids physicians and patients to achieve a specific level of glycemic control and to prevent hypoglycemia.In addition,SMBG empowers patients to achieve nutritional and physical activity goals,and helps physicians to optimize the different hypoglycemic therapies as demonstrated in the St Carlos study.This article describes the different ways of using this educational and therapeutic tool from the medical point of view as well as from the patient’s perspective.

A Pest Management Epidemic Model with Time Delay and Stage-Structure

In this paper, an SI epidemic model with stage structure is investigated. In this model, impulsive biological control which release infected pest to the field at a fixed time periodically is considered, and obtained the sufficient conditions for the global attractivity of pest-extinction periodic solution and permanence of the system. We also prove that all solutions of the model are uniformly ultimately bounded. The sensitive analysis on the two thresholds and to the changes of the releasing amounts of infected pest is shown by numerical simulations. Our results provide a reliable tactic basis for the practice of pest management.

Research on Web-Based Product Structure and Configuration Management

An enhanced system architecture of Web-based product structure and configuration management system along with its, functions are is presented. The key techniques, such as construction of object models of product structure and product configuration, hybrid approach method in product configuration management, sharing and integration of heterogeneous product data, integration with other sub-systems, are discussed too. A prototype system is developed by J2EE technology.

Evolution of the Socio-cognitive Structure of Knowledge Management(1986–2015): An Author Co-citation Analysis

Purpose: The evolution of the socio-cognitive structure of the field of knowledge management(KM) during the period 1986–2015 is described. Design/methodology/approach: Records retrieved from Web of Science were submitted to author co-citation analysis(ACA) following a longitudinal perspective as of the following time slices: 1986–1996, 1997–2006, and 2007–2015. The top 10% of most cited first authors by sub-periods were mapped in bibliometric networks in order to interpret the communities formed and their relationships.Findings: KM is a homogeneous field as indicated by networks results. Nine classical authors are identified since they are highly co-cited in each sub-period, highlighting Ikujiro Nonaka as the most influential authors in the field. The most significant communities in KM are devoted to strategic management, KM foundations, organisational learning and behaviour, and organisational theories. Major trends in the evolution of the intellectual structure of KM evidence a technological influence in 1986–1996, a strategic influence in 1997–2006, and finally a sociological influence in 2007–2015.Research limitations: Describing a field from a single database can offer biases in terms of output coverage. Likewise, the conference proceedings and books were not used and the analysis was only based on first authors. However, the results obtained can be very useful to understand the evolution of KM research.Practical implications: These results might be useful for managers and academicians to understand the evolution of KM field and to(re)define research activities and organisational projects.Originality/value: The novelty of this paper lies in considering ACA as a bibliometric technique to study KM research. In addition, our investigation has a wider time coverage than earlier articles.

Species composition,structure,regeneration and management status of Jorgo-Wato Forest in west Wollega,Ethiopia

Species composition,structure,regeneration,and management status of Jorgo-Wato Forest(JWF)was studied.Number of individuals,diameter at breast height(dbh)and height of woody species(dbh≥2.5 cm)were counted and measured in each plot.Group discussions with local farmers residing around JWF were carried out to understand the management of the JWF.Forest structural attributes were computed using descriptive statistics;correlation was used to assess relationships between the structural variables.A total of 4313 individuals(dbh≥2.5 cm)with a density of 1477 ha-1 were recorded,the number of species and individuals decreasing with increasing dbh classes.Species with the highest Importance Value Index(IVI)were Pouteria adolfifriedericii(37.7),Syzygium guineense subsp.afromontanum(23.6),Dracaena afromontana(20.5),Chionanthus mildbraedii(15.9),and Croton macrostachyus(12.3).Overall distribution of woody plants across size classes exhibited a reverse J-pattern,suggesting a healthy population structure and good regeneration.Nevertheless,some species were not represented in smaller diameter classes,including juvenile phases,which indicate a lack of regeneration.For these species,monitoring and enrichment planting would be necessary,along with curbing illegal cutting and coffee farming in the natural forest.Management interventions in the JWF need to consider livelihood options and to respect the rights of local communities.

Service Life Prediction and Management of Concrete Bridge Structures Due to Corrosion

The increasing stocks of public infrastructure and serious deterioration of infrastructure systems due to corrosion present great financial, safety, technical and operational challenges to government organizations in charge of public infrastructure development and management. To meet those challenges, a performance-based life-cycle management model for reinforced concrete structures was proposed in this paper. This model predicts the life-cycle performance of infrastructure based on the corrosion-induced deterioration mechanism： condition index as well as performance limit states. A case study is provided to demonstrate the use of the proposed performance-based life-cycle cost management model.

Enhancing the Efficiency of the Management of Real Estate Companies through Organizational Structures

The article represents research on ways to make the management of real estate companies more efficient, starting from their structural organization. The organizational structure of the enterprise is a basic component of the general structure of the company and reflects the “anatomy of the enterprise” and the way of its conception, detailing, and implementation directly influence the activities required to achieve the objectives of the enterprise. On closer examination of a series of organizational charts of real estate management companies, the author observed a tendency to use organizational structures that are inefficient. The main objectives of this article are to bring into the practice of real estate management a model of beneficial organizational structure, both for the real estate management companies and for the construction companies that, besides the building activity, also deal with the management of their own real estate, and to emphasize the particular importance of the organizational structure of the company. The appreciation of the organizational structure represents the process of knowledge, understanding, and explanation of the existing situation through a detailed analysis of the factors that influence its condition through: the enterprise development strategy;the type and complexity of services;the size of the enterprise;the quality of human resources;the changes that take place in the external environment of the company, and last but not least, the legal framework and the statutes of the enterprise.

Fuzzy variable structure algorithms for active queue management with delay compensation

Based on the linearized model of the TCP connections through the congested routers, this paper puts forward an active queue management algorithm (FVS-T). The algorithm utilizes the fuzzy variable structure control algorithm with delay factor to compensate time varying round-trip times (RTT) and uncertainties with respect to the number of active TCP sessions. By analyzing the robustness and performance of the control scheme for the nonlinear TCP/AQM model, we show that the proposed design has good performance and robustness, which are central to the notion of AQM. Implementation issues were discussed and ns simulations were provided to validate the design and compare its performance to other peer schemes in different scenarios. The results show that the proposed design significantly outperforms the other congestion schemes in terms of packet loss ratio, throughput and buffer fluctuation.

The Separation of Powers from Functions and the Establishment of a New Structure of Management and Operation of State-owned Assets

The development of the socialist market economy demands the furtherintensification of the reform of the management operating system (MOS)of the state-owned assets, the strengthening of the efficiency in the man-agement of state-owned assets,and the improvement of the operating bene-

An efficient spatio-temporal data structure for multi version management of engineering drawings

In the engineering database system, multiple versions of a design including engineering drawings should be managed efficiently. The paper proposes an efficient spatial data structure, that is an expansion of the R tree and HR tree, for version management of engineering drawings. A novel mechanism to manage the difference between drawings is introduced to the HR tree to eliminate redundant duplications and to reduce the amount of storage required for the data structure. Data management mechanism and structural properties of our data structure called the MVR + tree are described.

Circulation of Development Factors Promoted by Innovation of Land Management Under Background of Rural Vitalization:A Case Study of Tengtou Village in Zhejiang Province,China

Land is the space carrier for the existence and flow of other development factors.Activating rural land and promoting the circulation of other development factors through land management innovation is necessary to realize rural vitalization.This paper identifies the connotation of factor flow in the rural vitalization context,the action mechanism of land management innovation to boost the flow of development factors,the issues and obstacles restricting factor circulation,and the realization mechanism of the flow of development factors in rural vitalization.Based on the analytic paradigm constructed in the paper,the successful practice of promoting the flow of development factors through innovative land management in a model village is examined.The results show that:1)the unreasonable systems characterized by the land use system in rural areas are the main obstacles causing circulation issues in development factors.It is essential to engage in comprehensive reform to break down these long-lasting obstacles to the smooth flow of development factors.2)The land should play a leading role in the circulation of development factors in the background of rural vitalization;the main purpose of land management innovation is to activate the land factor,thereby promoting the circulation of other factors.3)The activated land factor will act as a‘trigger’to promote capital and technology in rural settings and use capital and technology to attract the inflow of talents and the return of migrant workers,whereby the population factor will act as a‘catalyst’for the cultivation of rural culture,bringing about the integration of various development factors.4)The innovation of land use and management,increased funding,and new technologies have brought multiple talents to Tengtou Village.The high-frequency mutual feedback between the village’s own and the external development factors resulted in its successful integration of industrial development.

From landslide characterization to nature reserve management:The“Scialimata Grande di Torre Alfina”landslide Geosite(Central Apennines,Italy)

Italy is characterized by widespread geomorphological instability,among which landslides leave impressive marks on the landscape.Nevertheless,landslide bodies may represent key sites for thematic and educational itineraries,especially in protected areas,where their management becomes an important issue.Our study focuses on the"Monte Rufeno Nature Reserve"(Central Apennines,Italy),where iconic landslides are present.Here,the"Scialimata Grande di Torre Alfina"landslide(SGTA)is listed in the regional Geosite database.This work aims to propose a multiscale procedure for landslide analysis,in terms of both hazard sources but also educational and geoheritage enhancement opportunities in natural reserves.After performing a Landslide Susceptibility conditional Analysis(LSA)for the reserve territory,attention was focused on the SGTA,to define properly its features and morphodynamics.A multi-disciplinary approach was adopted,by applying both remote sensing(UAV structure from motion,Photointerpretation)and field survey(geomorphological and GPS monitoring).From the LSA,based on drainage density,curvature,and slope triggering factors,the road and trail susceptibility maps were derived,as base tools for future risk assessments and trail paths management within the reserve.At the SGTA scale,the monitoring showed a displacement of up to 23 m during the time interval between 2015 and 2018.The landslide dynamics seem to be driven by alternating dry and extremely wet periods;moreover,leaks from the aqueduct in the detachment area and piping effects through clays may have also decreased the substrate cohesion.The SGTA complex influence on the Paglia River valley geometry was also hypothesized,underlining the action of landslide through different spatial scales(on-site and off-site)and on different environment features(sediment connectivity,hydrology).Finally,the SGTA appears highly representative of the geomorphic dynamics within the Nature Reserve(i.e.,scientific value)and it could be classified as an active geosite.Since the site was featured by a tourist trail,adequate management strategies must be adopted,considering the educational value and safety issues.

Impacts of species depletion on the food web structure of a marine ecosystem based on topological network analysis

Single-species management ignores the interactions between species,and ecosystem-based fisheries management(EBFM)has become a main method to fisheries management.Understanding food web structures and species interactions is essential for the implementation of EBFM and maintenance of ecosystem functions.Overfishing is one of the main reasons behind the depletion,which could even lead to the depletion of some target species in local areas.So understanding the impacts of species depletion on food web structures is important for the implementation of EBFM.The impacts of species depletion can be transmitted through the food web and cause the local extinction of both target and non-target species.In this study,topological network analysis was applied to examine the impacts of species depletion on the food web structure of Haizhou Bay.Results showed that fine crayfish Leptochela gracilis,squid Loligo sp.,and Japanese snapping shrimp Alpheus japonicus have the highest numbers of outgoing links(48,32 and 31 respectively);thus,these species may be considered key prey species.Whitespotted conger Conger myriaster,fat greenling Hexagrammos otakii,and bluefin gurnard Chelidonichthys kumu were key predators with the highest number of incoming links(37,36 and 35 respectively).The competition graphs derived from the Haizhou Bay food web were highly connected(more than 40%predators sharing over 10 common prey species),and showed close trophic interaction between high trophic level fishes.Simulation analysis showed that the food web structure has small changes to the depletion of species in a highly complex food web.The most-connected target species did not necessarily indicate high structural importance;however,some species with low connectivity may demonstrate stronger trophic interactions and play important ecological roles in the food web.But most species were more sensitive to the depletion of the most-connected target species than other target species(for instance,for zooplankton,closeness centrality 13.876 in D6,but closeness centrality 82.143 in original food web).Therefore,EBFM should focus on the most-connected target species,but also on those species with few but strong links and feeding relationships in the food web.

Low Carbon Building Design Optimization Based on Intelligent Energy Management System

The construction of relevant standards for building carbon emission assessment in China has just started,and the quantitative analysis method and evaluation system are still imperfect,which hinders the development of low-carbon building design.Therefore,the use of intelligent energy management system is very necessary.The purpose of this paper is to explore the design optimization of low-carbon buildings based on intelligent energy management systems.Based on the proposed quantitative method of building carbon emission,this paper establishes the quota theoretical system of building carbon emission analysis,and develops the quota based carbon emission calculation software.Smart energy management system is a low-carbon energy-saving system based on the reference of large-scale building energy-saving system and combined with energy consumption.It provides a fast and effective calculation tool for the quantitative evaluation of carbon emission of construction projects,so as to realize the carbon emission control and optimization in the early stage of architectural design and construction.On this basis,the evaluation,analysis and calculation method of building structure based on carbon reduction target is proposed,combined with the carbon emission quota management standard proposed in this paper.Taking small high-rise residential buildings as an example,this paper compares and analyzes different building structural systems from the perspectives of structural performance,economy and carbon emission level.It provides a reference for the design and evaluation of low-carbon building structures.The smart energy management system collects user energy use parameters.It uses time period and time sequence to obtain a large amount of data for analysis and integration,which provides users with intuitive energy consumption data.Compared with the traditional architectural design method,the industrialized construction method can save 589.22 megajoules(MJ)per square meter.Based on 29270 megajoules(MJ)per ton of standard coal,the construction area of the case is about 8000 m2,and the energy saving of residential buildings is 161.04 tons of standard coal.This research is of great significance in reducing the carbon emission intensity of buildings.

Reflections on Research and Development Management Innovation in Huawei Enterprises

As an advanced global provider of information and communication technology solutions,Huawei has always maintained a leading position in the ICT field and is committed to achieving a future information society and building a better fully connected world.Looking at the rapid development of Huawei,it is inseparable from its comprehensive and advanced enterprise management innovation concept,which is also one of the main reasons for helping Huawei become a world-class enterprise.“Huawei has not succeeded,it is just growing”is a famous quote from Ren Zhengfei,the main founder and president of Huawei.In the context of the rapid development of the Internet industry and information technology,enterprises must establish the concept of innovative development,implement innovation management,and create a good production and development environment.This paper analyzes the content of Huawei’s enterprise management innovation,including Huawei’s management philosophy,management mode,management status quo,and management innovation suggestions,understands and grasps the choice of enterprise management mode,learns advanced enterprise management experience,and provides reference for other enterprises to practice innovation management.