Objective: Patients with malignant gliomas have to adjust their daily lives because of the threat of impending death and declining abilities.Thus,clarifying the process of life adjustment in such patients would help t...Objective: Patients with malignant gliomas have to adjust their daily lives because of the threat of impending death and declining abilities.Thus,clarifying the process of life adjustment in such patients would help them lead a normal life.To clarify the process of life adjustment in patients at the onset of glioma,who continuously receive oral anticancer drug.Methods: The study institution consisted of two designated cancer centers.Semi-structured interviews were conducted with 10 patients,and the data were analyzed using the Modified Grounded Theory Approach of Kinoshita (M-GTA).Results: As a core category representing the process of life adjustment in patients at the onset of glioma,"trials and errors for self-fulfillment even in a limited lifespan" was extracted.Patients began "seeking information about the unfamiliar life-threatening disease," and "imaging their uncertain lives after the disease and the resulting disability" while "conducting repeated trials and errors to establish coping methods according to their abilities." When facing difficulties in such trials and errors,they reported "losing self-confidence due to unexpected limitations." However,they regulated their feelings by "resigning themselves to their unchangeable reality." Contrarily,as "functional improvement enhanced their motivation to recover," they attempted to promote functional recovery and organized their daily lives in "fulfilling their desires in their limited lifespan." Conclusion: The process of life adjustment in patients with malignant gliomas involved identifying a way of living despite limited lifespan.To ensure appropriate nursing care for patients at the onset of glioma,it is important to help them establish coping methods in accordance with their abilities.展开更多
The need to prevent cancer leads the authors to propose three innovative courses of cancer as categories of disease. Theobjectives of the research are to study the impact of different factors on adaptation to the recu...The need to prevent cancer leads the authors to propose three innovative courses of cancer as categories of disease. Theobjectives of the research are to study the impact of different factors on adaptation to the recurrence of cancer and to assess the qualityof life, the anxiety as a state and the depression as a state and the evolution of the disease on a period of three months. During thislongitudinal and prospective study, the author met 32 subjects after announcing the recurrence of their cancer, and saw again 21 of them,three months later. In two times of the study, the author made fill out several questionnaires concerning various variables. The mainresults allow showing that the majority of the subjects did not present new recurrence of cancer and that the use of the Fighting spiritstrategy is representative of them. The author＇s linear regressions and the author＇s comparisons of averages allowed the authors severalrelations about to different categories of disease. Supporting therapies and management programs for stress would be beneficial for thepatients who have recurrence of their cancer.展开更多
目的了解1990-2019年中国慢性阻塞性肺疾病发病、患病、死亡情况及疾病负担情况,预测2020-2030年中国慢性阻塞性肺疾病发病情况,为评估和制定慢性阻塞性肺疾病相关预防治疗政策和措施提供数据支持。方法利用2019年全球疾病负担研究数据...目的了解1990-2019年中国慢性阻塞性肺疾病发病、患病、死亡情况及疾病负担情况,预测2020-2030年中国慢性阻塞性肺疾病发病情况,为评估和制定慢性阻塞性肺疾病相关预防治疗政策和措施提供数据支持。方法利用2019年全球疾病负担研究数据库(Global burden of disease study,GBD),研究分析1990-2019年中国慢性阻塞性肺疾病的发病、患病、死亡、伤残调整寿命年(DALY)、早死寿命损失年(YLL)、伤残寿命损失年(YLD)等情况。采用贝叶斯-时期-队列分析(BAPC)方法,预测2020-2030年中国慢性阻塞性肺疾病发病率。结果相对于1990年,2019年中国慢性阻塞性肺疾病粗患病率增长35.44%,标化患病率减少27.16%,粗发病率增长38.31%,标化发病率减少28.52%,粗死亡率减少30.59%,标化死亡率减少70.08%。1990-2019年中国人群因慢性阻塞性肺疾病导致的YLL率由3281.48/10万降至862.37/10万,YLD率由330.33/10万降至240.40/10万,DALY率由3611.81/10万降至1102.77/10万。2019年男性慢性阻塞性肺疾病DALY率相比于1990年降低66.56%,女性DALY率相比于1990年降低71.87%。2020-2030年中国慢性阻塞性肺疾病标化发病率预计呈下降趋势,2030年男性标化发病率预计比2020年降低31.97%,女性标化发病率预计比2020年降低27.69%。结论1990-2019年,慢性阻塞性肺疾病对中国人口造成的疾病负担总体呈下降趋势。但从患病情况和死亡情况来看,发病及死亡人数较多,中国慢性阻塞性肺疾病的疾病负担仍处于较高水平。同时预测结果显示,未来10年中国慢性阻塞性肺疾病标化发病率在下降,但是仍处于较高水平,因此进行早筛查、早预防和早治疗,及广泛开展慢阻肺相关知识普及,对于做好COPD疾病管理具有重要意义。展开更多
目的:分析海南省1990至2019年肝癌疾病负担的变化趋势及其危险因素归因情况。方法:根据2019年全球疾病负担(Global Burden of Disease,GBD)研究的海南省数据,利用Joinpoint回归模型分析1990至2019年海南省肝癌发病、死亡、伤残调整寿命...目的:分析海南省1990至2019年肝癌疾病负担的变化趋势及其危险因素归因情况。方法:根据2019年全球疾病负担(Global Burden of Disease,GBD)研究的海南省数据,利用Joinpoint回归模型分析1990至2019年海南省肝癌发病、死亡、伤残调整寿命年(disability-adjusted life year,DALY)的变化趋势,平均年度变化百分比(average annual percentage change,AAPC)用于描述年平均变化趋势,年度变化百分比(annual percentage change,APC)用于描述不同阶段时间变化趋势,归因DALY率用于描述危险因素归因情况。结果:1990至2019年海南省肝癌年龄标化发病率、年龄标化死亡率及年龄标化DALY率均呈下降趋势,分别下降了59.30%、61.21%和64.03%(P<0.001)。1990至2019年海南省40岁以下人群肝癌的年龄标化DALY率均较低,1990年的年龄标化DALY率的峰值出现在55~59岁年龄组,2019年后移至75~79岁年龄组。在1990至2019年期间,吸烟一直是海南省肝癌归因DALY率的主要危险因素,而在2019年,高BMI已经超越了药物使用因素,成为肝癌疾病负担的第三大危险因素。结论:海南省肝癌疾病负担总体呈下降趋势,峰值年龄段后移,吸烟、饮酒和高BMI仍是主要危险因素,应继续加强肝癌的早诊早治及危险因素干预等防控工作。展开更多
基金This work was supported by the Grants-in-Aid for Scientific Research from the Ministry of Education,Culture,Sports,Science and Technology of Japan (Grant-in-Aid for Young Scientists.No.B16K20780) in 2016-2018
文摘Objective: Patients with malignant gliomas have to adjust their daily lives because of the threat of impending death and declining abilities.Thus,clarifying the process of life adjustment in such patients would help them lead a normal life.To clarify the process of life adjustment in patients at the onset of glioma,who continuously receive oral anticancer drug.Methods: The study institution consisted of two designated cancer centers.Semi-structured interviews were conducted with 10 patients,and the data were analyzed using the Modified Grounded Theory Approach of Kinoshita (M-GTA).Results: As a core category representing the process of life adjustment in patients at the onset of glioma,"trials and errors for self-fulfillment even in a limited lifespan" was extracted.Patients began "seeking information about the unfamiliar life-threatening disease," and "imaging their uncertain lives after the disease and the resulting disability" while "conducting repeated trials and errors to establish coping methods according to their abilities." When facing difficulties in such trials and errors,they reported "losing self-confidence due to unexpected limitations." However,they regulated their feelings by "resigning themselves to their unchangeable reality." Contrarily,as "functional improvement enhanced their motivation to recover," they attempted to promote functional recovery and organized their daily lives in "fulfilling their desires in their limited lifespan." Conclusion: The process of life adjustment in patients with malignant gliomas involved identifying a way of living despite limited lifespan.To ensure appropriate nursing care for patients at the onset of glioma,it is important to help them establish coping methods in accordance with their abilities.
文摘The need to prevent cancer leads the authors to propose three innovative courses of cancer as categories of disease. Theobjectives of the research are to study the impact of different factors on adaptation to the recurrence of cancer and to assess the qualityof life, the anxiety as a state and the depression as a state and the evolution of the disease on a period of three months. During thislongitudinal and prospective study, the author met 32 subjects after announcing the recurrence of their cancer, and saw again 21 of them,three months later. In two times of the study, the author made fill out several questionnaires concerning various variables. The mainresults allow showing that the majority of the subjects did not present new recurrence of cancer and that the use of the Fighting spiritstrategy is representative of them. The author＇s linear regressions and the author＇s comparisons of averages allowed the authors severalrelations about to different categories of disease. Supporting therapies and management programs for stress would be beneficial for thepatients who have recurrence of their cancer.
文摘目的了解1990-2019年中国慢性阻塞性肺疾病发病、患病、死亡情况及疾病负担情况,预测2020-2030年中国慢性阻塞性肺疾病发病情况,为评估和制定慢性阻塞性肺疾病相关预防治疗政策和措施提供数据支持。方法利用2019年全球疾病负担研究数据库(Global burden of disease study,GBD),研究分析1990-2019年中国慢性阻塞性肺疾病的发病、患病、死亡、伤残调整寿命年(DALY)、早死寿命损失年(YLL)、伤残寿命损失年(YLD)等情况。采用贝叶斯-时期-队列分析(BAPC)方法,预测2020-2030年中国慢性阻塞性肺疾病发病率。结果相对于1990年,2019年中国慢性阻塞性肺疾病粗患病率增长35.44%,标化患病率减少27.16%,粗发病率增长38.31%,标化发病率减少28.52%,粗死亡率减少30.59%,标化死亡率减少70.08%。1990-2019年中国人群因慢性阻塞性肺疾病导致的YLL率由3281.48/10万降至862.37/10万,YLD率由330.33/10万降至240.40/10万,DALY率由3611.81/10万降至1102.77/10万。2019年男性慢性阻塞性肺疾病DALY率相比于1990年降低66.56%,女性DALY率相比于1990年降低71.87%。2020-2030年中国慢性阻塞性肺疾病标化发病率预计呈下降趋势,2030年男性标化发病率预计比2020年降低31.97%,女性标化发病率预计比2020年降低27.69%。结论1990-2019年,慢性阻塞性肺疾病对中国人口造成的疾病负担总体呈下降趋势。但从患病情况和死亡情况来看,发病及死亡人数较多,中国慢性阻塞性肺疾病的疾病负担仍处于较高水平。同时预测结果显示,未来10年中国慢性阻塞性肺疾病标化发病率在下降,但是仍处于较高水平,因此进行早筛查、早预防和早治疗,及广泛开展慢阻肺相关知识普及,对于做好COPD疾病管理具有重要意义。
