Taking landscape design of Suburban Park in Yulin City for example, this paper applied the design thoughts of integrating multiple planning, defining concepts and objectives, specified the design strategies of restori...Taking landscape design of Suburban Park in Yulin City for example, this paper applied the design thoughts of integrating multiple planning, defining concepts and objectives, specified the design strategies of restoring ecology, improving life and promoting production, and disclosed the landscape design mode based on the integration of ecology, production and life in which ecological landscapes, productive landscapes and living landscapes promote and coexist harmoniously with each other.展开更多
Thermal mechanical cyclic strain tests were carried out under in-phase andout-of-phase conditions on a Nickel-base Superalloy GH4133 in the temperature range of 571-823 degC. Based on analyzing the present models of T...Thermal mechanical cyclic strain tests were carried out under in-phase andout-of-phase conditions on a Nickel-base Superalloy GH4133 in the temperature range of 571-823 degC. Based on analyzing the present models of TMF (thermal mechanical fatigue) life prediction, a newmodel for predicting nickel-base superalloy TMF lifetime was proposed. TMF life of superalloy GH4133was calculated accurately based on the new model. Experimental TMF life has been compared with thecalculated results and all results fall in the scatter band of 1.5. The calculating results showthat the new model is not only simple, but also precise. This model will play great roles as lifeprediction of the metal materials and the engineering components subjected to non-isothermal serviceconditions.展开更多
Shorter product life cycles present new dressed in supply chain literature. This research challenges to managing production and logistics not adequately adaddresses issues pertaining to the management of supply chains...Shorter product life cycles present new dressed in supply chain literature. This research challenges to managing production and logistics not adequately adaddresses issues pertaining to the management of supply chains in a short life cycle environment. In this paper, we study the short life cycle environment; then we develop the ventory policy of the indirect manufacturer by explicitly using his demand us an output of the retailer's optimal inoptimal ordering policy. Finally, we also provide causes of the bullwhip effect in the context of short life cycle products.展开更多
Copper consumption increased very quickly in China in recent years,which could not be met by inland copper industry.In order to achieve a sustainable development of copper industry,an analysis of copper recycling in C...Copper consumption increased very quickly in China in recent years,which could not be met by inland copper industry.In order to achieve a sustainable development of copper industry,an analysis of copper recycling in China was necessary.For the life cycle of copper products a copper-flow diagram with time factor was worked out and the contemporary copper recycling in China was analyzed,from which the following data were obtained.The average life cycle of copper products was 30 years.From 1998 to 2002,the use ratio of copper scraps in copper production,the use ratio of copper scraps in copper manufacture,the materials self-support ratio in copper production,and the materials self-support ratio in copper manufacture were 26.50%,15.49%,48.05% and 59.41%,respectively.The materials self-support ratios in copper production and manufacture declined year by year in recent years on the whole,and the latter dropped more quickly.The average index of copper ore and copper scrap from 1998 to 2002 were 0.8475 t/t and 0.0736 t/t,respectively;and copper resource efficiency was 1.1855 t/t.Some efforts should be paid to reduce copper ores consumption and promote copper scraps regeneration.Copper scraps were mostly imported from foreign countries because of shortage in recent years in China.Here the reasons related to copper scraps deficiency were also demonstrated.But we can forecast:when copper production was in a slow rise or in a steady state in China,the deficiency of copper scraps may be mitigated;when copper production was in a steady state for a very long time,copper scraps may become relatively abundant.According to the status of copper industry in China,the raw materials of copper production and manufacture have to depend on oversea markets heavily in recent years,and at the same time,the copper scraps using proportion and efficiency in copper industry should be improved.展开更多
This paper considers an optimal sequential inspection schedule for a second-hand product after that the free nonrenewable warranty is expired. The length of warranty is prespecified and during the warranty period, the...This paper considers an optimal sequential inspection schedule for a second-hand product after that the free nonrenewable warranty is expired. The length of warranty is prespecified and during the warranty period, the product is minimally repaired by the dealer when it fails. Following the expiration of the non-renewing warranty, the product is inspected and upgraded sequentially a fixed number of times at the expenses of the customer.At each inspection, the failure rate of the product is reduced proportionally so that the product is upgraded. The product is assumed to deteriorate as it ages and the replacement of the product occurs when a fixed number of inspections are rendered. In addition,the intervals between two successive inspections are assumed to decrease monotonically. The main objective of this paper is to determine the optimal improvement level to upgrade the product at each inspection so that the expected maintenance cost during the life cycle of the product is minimized from the perspective of the customer. Under the given cost structures, we derive an explicit formula to obtain the expected maintenance cost incurred during the life cycle of the product and discuss the method to find the optimal level of the improvement analytically in case the failure times follow the Weibull distribution. Numerical results are analyzed to observe the impact of relevant parameters on the optimal solution.展开更多
In order to study the characteristics of species composition, richness and aboveground biomass of natural grasslands, and then ifnd out the relations between species richness and aboveground productivity of the commun...In order to study the characteristics of species composition, richness and aboveground biomass of natural grasslands, and then ifnd out the relations between species richness and aboveground productivity of the communities and possible mechanisms to form the relations, four typical grassland communities (Artemisia capillaries (AC), Thymus quinquecostatus (TQ), Stipa bungeana (SB) and Stipa grandis (SG)) along with a succession sequence in hilly-gully regions of the Loess Plateau, China, were investigated by ifeld survey and laboratory analysis. The results were summarized as follows:Different succession stages had different species compositions as well as different proportions of plant life forms and photosynthetic types, and Asteraceae, Poaceae and Leguminosae were their dominant species as well as their dominant perennial herb species;and different succession stages had signiifcantly different species richness and aboveground biomasses. There were many relation patterns (linear positive correlation, unrelated relations and unimodal relations) between the species richness and aboveground biomass in different succession stages and a signiifcant unimodal relation between the species richness and aboveground biomass in all the grassland communities and the highest species diversity appeared at a moderate level of productivity. The results suggest the unimodal relations in all the grassland communities are accumulative results of the relations in each succession stage.展开更多
The serious competition environment of global marke t requests the enterprise to change traditional product development strategy and a dopt new theory in order to meet diverse customer needs while maintaining near m a...The serious competition environment of global marke t requests the enterprise to change traditional product development strategy and a dopt new theory in order to meet diverse customer needs while maintaining near m ass production efficiency, which is the main philosophy of mass customization. P roduct family design is research focus at present and also is the core technolog y of DFMC (design for mass customization). Firstly, this paper explores the fund amental issues of product family, such as concepts of modularity, commonality/di versity, product platform and product family architecture etc. We compare the te rminology between product family and object-oriented approach in the next step. Thirdly, this paper puts forwards one product family design methodology based o n product platform and under different phase of product life cycle constrains, f or example, functional, assembly and service etc. At the end section of this pap er, we applied, the object-oriented approach in above mentioned product family design methodology to realize the design process. In one word, this paper propos ed one product family design methodology based on object oriented approach and p roduct life cycle consideration, especially the conjointness of characteristic o f OOA and concepts of product family. The main property of OOA are encapsulation , inherence and polymorphism. Encapsulation can represent the module or building blocks of product family. Inherence can be extended to describe the modularity and commonality, and also be used to construct variant space. Alternative specif ic of product family architecture can be embodied with polymorphism. And fin aly, we give the future work contents. In order to derive the product platform a nd achieve modularity and commonality/diversity, interface management between bu ilding block is necessary. The question is how the OOA can be applied in interfa ce management to get our aim OOA is the basis of many information management sy stem, then the question is how to build one system to manage the information of product family and support mass customization The third question is how to deve lop one computer aided tool to facilitate the application of OOA for product fam ily design, even be used to category of design for mass customization.展开更多
Climate change is an ever growing issue and a major concem worldwide. Both producers and processors need to address the issue now by reducing, their carbon footprint. Additionally, if Ireland is to meet their climate ...Climate change is an ever growing issue and a major concem worldwide. Both producers and processors need to address the issue now by reducing, their carbon footprint. Additionally, if Ireland is to meet their climate and energy targets, as outlined in Food Harvest 2020, which outlines a range ot objectives for the Irish agricultural sector, the efficient use of resources and fuels within the industry will need to be increased. In Ireland, agriculture accounts for 29.2% of the total greenhouse gas powder, is examined in order to estimate the global warming potential (GWP) associated with its manufacture using life cycle assessment. A cradle-to-processing factory gate analysis, which includes raw milk production, raw milk transportation to the processmg tactory, its processing into eacla product and product packaging, is assessed in this study using data collected circa 2013. The factories surveyed processed approximately 24% of the total raw milk processed in the Republic of Ireland in 2013, which was 5.83 billion liter. The average total GWP associated with the manufacture of milk powder is 9.731 kg CO2eq·kg^-1 milk powder, which has a standard deviation of 2.26 kg CO2eq·kg^-1 milk powder, for the life cycle stages analyzed in this study. The most significant contributor to GWP is raw milk production (84%), followed by dairy processing (14%), with the remainder of the life cycle stages contributing approximately 2%.展开更多
The industrial system should learn from the natural ecosystem. The resource utilization efficiency should be increased and the environmental load should be decreased, depending on the materials recycled in the system....The industrial system should learn from the natural ecosystem. The resource utilization efficiency should be increased and the environmental load should be decreased, depending on the materials recycled in the system. The classification of industrial materials from the viewpoint of large-scale recycling was stated. Recycling of materials, on three different levels, was introduced in the industrial system. The metal flow diagram in the life cycle of products, in the case of no materials recycled, materials partially recycled, and materials completely recycled, was given. The natural resource conservation and the waste emission reduction were analyzed under the condition of materials completely recycled. The expressions for the relation between resource efficiency and material recycling rate, and the relation between eco-efficiency and material recycling rate were derived, and the curves describing the relationship between them were protracted. The diagram of iron flow in the life cycle of iron and steel products in China, in 2001, was given, and the iron resource efficiency, material recycling rate, and iron eco-efficiency were analyzed. The variation of iron resource efficiency with the material recycling rate was analyzed for two different production ratios.展开更多
The current research elucidates the advertising scheme of automotive innovation by incorporating the various stages of the product life cycle.The study proposes an empirical model for the automotive industry to evalua...The current research elucidates the advertising scheme of automotive innovation by incorporating the various stages of the product life cycle.The study proposes an empirical model for the automotive industry to evaluate a time-point known as a switch-point or a take-off point at which firms should modify the advertising and sales promotion strategies to boost sales volume.The problem applies a time-series innovation diffusion model wherein adoption rate changes when a product enters a growth stage and then again when the company stops the advertising campaign in the maturity stage.The present paper develops a profit maximization problem,which optimizes the overall advertising duration and advertising take-off point.A numerical illustration is provided using the actual sales data of automobile industries,and sensitivity analysis is further performed to validate the effect of critical parameters on the optimization problem.展开更多
In addition to being environmentally friendly,remanufactured products are popular with consumers because they offer the latest technology at a lower price,in comparison to brand new products.However,some consumers hes...In addition to being environmentally friendly,remanufactured products are popular with consumers because they offer the latest technology at a lower price,in comparison to brand new products.However,some consumers hesitate to buy remanufactured products because they are skeptical about their quality.Thus,they are unsure of the extent to which the product will render services when compared to a new product.A promotional marketing strategy employed by remanufacturers is to offer warranties for these products.To that end,this study scrutinizes the impact of offering non-renewing warranties on remanufactured products.Specifically,in this paper,a methodology is suggested,which simultaneously minimizes the cost incurred by the remanufacturers and maximizes consumer confidence toward buying remanufactured products.This study uses a discrete-event simulation to optimize the implementation of a two-dimensional non-renewing warranty policy for remanufactured products.The implementation is illustrated using a specific product recovery system called the Advanced Remanufacturing-To-Order system.The experiments in the study were designed using Taguchi’s Orthogonal Arrays to represent the entire domain of the recovery system to observe system behavior under various experimental conditions.展开更多
Obsolescence of integrated systems which contain hardware and software is a problem that affects multiple industries and can occur for many reasons,including technological,economic,organizational,and social factors.It...Obsolescence of integrated systems which contain hardware and software is a problem that affects multiple industries and can occur for many reasons,including technological,economic,organizational,and social factors.It is especially acute in products and systems that have long life cycles,where a high rate of technological innovation of the subcomponents result in a mismatch in life cycles between the components and the systems.While several approaches for obsolescence forecasting exist,they often require data that may not be available.This paper describes an approach using non-probabilistic scenarios coupled with decision analysis to investigate how particular scenarios influence priority setting for products and systems.Scenarios are generated from a list of emergent and future conditions related to obsolescence.The key result is an identification of the most and least disruptive scenarios to the decision maker’s priorities.An example is presented related to the selection of technologies for energy islanding,which demonstrates the methodology using six obsolescence scenarios.The paper should be of broad interest to scholars and practitioners engaged with enterprise risk management and similar challenges of large-scale systems.展开更多
The burden of injuries is underestimated to an evengreater extent in developing countries than inindustrialized countries. The objective of this paper is toanalyze injuries and diseases in the monitored work place
基金Sponsored by National Natural Science Foundation of China(51178372/E080201)Humanities and Social Science Program of Northwest A&F University(2015RWYB38)
文摘Taking landscape design of Suburban Park in Yulin City for example, this paper applied the design thoughts of integrating multiple planning, defining concepts and objectives, specified the design strategies of restoring ecology, improving life and promoting production, and disclosed the landscape design mode based on the integration of ecology, production and life in which ecological landscapes, productive landscapes and living landscapes promote and coexist harmoniously with each other.
文摘Thermal mechanical cyclic strain tests were carried out under in-phase andout-of-phase conditions on a Nickel-base Superalloy GH4133 in the temperature range of 571-823 degC. Based on analyzing the present models of TMF (thermal mechanical fatigue) life prediction, a newmodel for predicting nickel-base superalloy TMF lifetime was proposed. TMF life of superalloy GH4133was calculated accurately based on the new model. Experimental TMF life has been compared with thecalculated results and all results fall in the scatter band of 1.5. The calculating results showthat the new model is not only simple, but also precise. This model will play great roles as lifeprediction of the metal materials and the engineering components subjected to non-isothermal serviceconditions.
文摘Shorter product life cycles present new dressed in supply chain literature. This research challenges to managing production and logistics not adequately adaddresses issues pertaining to the management of supply chains in a short life cycle environment. In this paper, we study the short life cycle environment; then we develop the ventory policy of the indirect manufacturer by explicitly using his demand us an output of the retailer's optimal inoptimal ordering policy. Finally, we also provide causes of the bullwhip effect in the context of short life cycle products.
基金Supported by Key Technologies R&D Programme(No.2003BA614A-02)
文摘Copper consumption increased very quickly in China in recent years,which could not be met by inland copper industry.In order to achieve a sustainable development of copper industry,an analysis of copper recycling in China was necessary.For the life cycle of copper products a copper-flow diagram with time factor was worked out and the contemporary copper recycling in China was analyzed,from which the following data were obtained.The average life cycle of copper products was 30 years.From 1998 to 2002,the use ratio of copper scraps in copper production,the use ratio of copper scraps in copper manufacture,the materials self-support ratio in copper production,and the materials self-support ratio in copper manufacture were 26.50%,15.49%,48.05% and 59.41%,respectively.The materials self-support ratios in copper production and manufacture declined year by year in recent years on the whole,and the latter dropped more quickly.The average index of copper ore and copper scrap from 1998 to 2002 were 0.8475 t/t and 0.0736 t/t,respectively;and copper resource efficiency was 1.1855 t/t.Some efforts should be paid to reduce copper ores consumption and promote copper scraps regeneration.Copper scraps were mostly imported from foreign countries because of shortage in recent years in China.Here the reasons related to copper scraps deficiency were also demonstrated.But we can forecast:when copper production was in a slow rise or in a steady state in China,the deficiency of copper scraps may be mitigated;when copper production was in a steady state for a very long time,copper scraps may become relatively abundant.According to the status of copper industry in China,the raw materials of copper production and manufacture have to depend on oversea markets heavily in recent years,and at the same time,the copper scraps using proportion and efficiency in copper industry should be improved.
基金supported by the Research Base Construction Fund Support Program funded by Chonbuk National University in 2013the Mid-career Research Program(2016R1A2B4010080)through NRF Grant funded by MEST
文摘This paper considers an optimal sequential inspection schedule for a second-hand product after that the free nonrenewable warranty is expired. The length of warranty is prespecified and during the warranty period, the product is minimally repaired by the dealer when it fails. Following the expiration of the non-renewing warranty, the product is inspected and upgraded sequentially a fixed number of times at the expenses of the customer.At each inspection, the failure rate of the product is reduced proportionally so that the product is upgraded. The product is assumed to deteriorate as it ages and the replacement of the product occurs when a fixed number of inspections are rendered. In addition,the intervals between two successive inspections are assumed to decrease monotonically. The main objective of this paper is to determine the optimal improvement level to upgrade the product at each inspection so that the expected maintenance cost during the life cycle of the product is minimized from the perspective of the customer. Under the given cost structures, we derive an explicit formula to obtain the expected maintenance cost incurred during the life cycle of the product and discuss the method to find the optimal level of the improvement analytically in case the failure times follow the Weibull distribution. Numerical results are analyzed to observe the impact of relevant parameters on the optimal solution.
基金funded by the Strategic Priority Research Program of the Chinese Academy of Sciences, China (XDA05050403)
文摘In order to study the characteristics of species composition, richness and aboveground biomass of natural grasslands, and then ifnd out the relations between species richness and aboveground productivity of the communities and possible mechanisms to form the relations, four typical grassland communities (Artemisia capillaries (AC), Thymus quinquecostatus (TQ), Stipa bungeana (SB) and Stipa grandis (SG)) along with a succession sequence in hilly-gully regions of the Loess Plateau, China, were investigated by ifeld survey and laboratory analysis. The results were summarized as follows:Different succession stages had different species compositions as well as different proportions of plant life forms and photosynthetic types, and Asteraceae, Poaceae and Leguminosae were their dominant species as well as their dominant perennial herb species;and different succession stages had signiifcantly different species richness and aboveground biomasses. There were many relation patterns (linear positive correlation, unrelated relations and unimodal relations) between the species richness and aboveground biomass in different succession stages and a signiifcant unimodal relation between the species richness and aboveground biomass in all the grassland communities and the highest species diversity appeared at a moderate level of productivity. The results suggest the unimodal relations in all the grassland communities are accumulative results of the relations in each succession stage.
文摘The serious competition environment of global marke t requests the enterprise to change traditional product development strategy and a dopt new theory in order to meet diverse customer needs while maintaining near m ass production efficiency, which is the main philosophy of mass customization. P roduct family design is research focus at present and also is the core technolog y of DFMC (design for mass customization). Firstly, this paper explores the fund amental issues of product family, such as concepts of modularity, commonality/di versity, product platform and product family architecture etc. We compare the te rminology between product family and object-oriented approach in the next step. Thirdly, this paper puts forwards one product family design methodology based o n product platform and under different phase of product life cycle constrains, f or example, functional, assembly and service etc. At the end section of this pap er, we applied, the object-oriented approach in above mentioned product family design methodology to realize the design process. In one word, this paper propos ed one product family design methodology based on object oriented approach and p roduct life cycle consideration, especially the conjointness of characteristic o f OOA and concepts of product family. The main property of OOA are encapsulation , inherence and polymorphism. Encapsulation can represent the module or building blocks of product family. Inherence can be extended to describe the modularity and commonality, and also be used to construct variant space. Alternative specif ic of product family architecture can be embodied with polymorphism. And fin aly, we give the future work contents. In order to derive the product platform a nd achieve modularity and commonality/diversity, interface management between bu ilding block is necessary. The question is how the OOA can be applied in interfa ce management to get our aim OOA is the basis of many information management sy stem, then the question is how to build one system to manage the information of product family and support mass customization The third question is how to deve lop one computer aided tool to facilitate the application of OOA for product fam ily design, even be used to category of design for mass customization.
文摘Climate change is an ever growing issue and a major concem worldwide. Both producers and processors need to address the issue now by reducing, their carbon footprint. Additionally, if Ireland is to meet their climate and energy targets, as outlined in Food Harvest 2020, which outlines a range ot objectives for the Irish agricultural sector, the efficient use of resources and fuels within the industry will need to be increased. In Ireland, agriculture accounts for 29.2% of the total greenhouse gas powder, is examined in order to estimate the global warming potential (GWP) associated with its manufacture using life cycle assessment. A cradle-to-processing factory gate analysis, which includes raw milk production, raw milk transportation to the processmg tactory, its processing into eacla product and product packaging, is assessed in this study using data collected circa 2013. The factories surveyed processed approximately 24% of the total raw milk processed in the Republic of Ireland in 2013, which was 5.83 billion liter. The average total GWP associated with the manufacture of milk powder is 9.731 kg CO2eq·kg^-1 milk powder, which has a standard deviation of 2.26 kg CO2eq·kg^-1 milk powder, for the life cycle stages analyzed in this study. The most significant contributor to GWP is raw milk production (84%), followed by dairy processing (14%), with the remainder of the life cycle stages contributing approximately 2%.
基金National Key Fundamental Research and Development Project of China (2005CB724206) National NaturalScience Foundation of China (50334020)
文摘The industrial system should learn from the natural ecosystem. The resource utilization efficiency should be increased and the environmental load should be decreased, depending on the materials recycled in the system. The classification of industrial materials from the viewpoint of large-scale recycling was stated. Recycling of materials, on three different levels, was introduced in the industrial system. The metal flow diagram in the life cycle of products, in the case of no materials recycled, materials partially recycled, and materials completely recycled, was given. The natural resource conservation and the waste emission reduction were analyzed under the condition of materials completely recycled. The expressions for the relation between resource efficiency and material recycling rate, and the relation between eco-efficiency and material recycling rate were derived, and the curves describing the relationship between them were protracted. The diagram of iron flow in the life cycle of iron and steel products in China, in 2001, was given, and the iron resource efficiency, material recycling rate, and iron eco-efficiency were analyzed. The variation of iron resource efficiency with the material recycling rate was analyzed for two different production ratios.
基金The research work presented in this paper is supported by the grants to the first and third authors from DST,via DST PURSE phase II,India.
文摘The current research elucidates the advertising scheme of automotive innovation by incorporating the various stages of the product life cycle.The study proposes an empirical model for the automotive industry to evaluate a time-point known as a switch-point or a take-off point at which firms should modify the advertising and sales promotion strategies to boost sales volume.The problem applies a time-series innovation diffusion model wherein adoption rate changes when a product enters a growth stage and then again when the company stops the advertising campaign in the maturity stage.The present paper develops a profit maximization problem,which optimizes the overall advertising duration and advertising take-off point.A numerical illustration is provided using the actual sales data of automobile industries,and sensitivity analysis is further performed to validate the effect of critical parameters on the optimization problem.
文摘In addition to being environmentally friendly,remanufactured products are popular with consumers because they offer the latest technology at a lower price,in comparison to brand new products.However,some consumers hesitate to buy remanufactured products because they are skeptical about their quality.Thus,they are unsure of the extent to which the product will render services when compared to a new product.A promotional marketing strategy employed by remanufacturers is to offer warranties for these products.To that end,this study scrutinizes the impact of offering non-renewing warranties on remanufactured products.Specifically,in this paper,a methodology is suggested,which simultaneously minimizes the cost incurred by the remanufacturers and maximizes consumer confidence toward buying remanufactured products.This study uses a discrete-event simulation to optimize the implementation of a two-dimensional non-renewing warranty policy for remanufactured products.The implementation is illustrated using a specific product recovery system called the Advanced Remanufacturing-To-Order system.The experiments in the study were designed using Taguchi’s Orthogonal Arrays to represent the entire domain of the recovery system to observe system behavior under various experimental conditions.
基金This work was supported in part by the National Science Foundation Grant 1747767"Planning IUCRC University of Virginia:Center for Hardware and Embedded System Security and Trust(CHEST)",and in part by the Commonwealth Center for Advanced Logistics Systems(CCALS).
文摘Obsolescence of integrated systems which contain hardware and software is a problem that affects multiple industries and can occur for many reasons,including technological,economic,organizational,and social factors.It is especially acute in products and systems that have long life cycles,where a high rate of technological innovation of the subcomponents result in a mismatch in life cycles between the components and the systems.While several approaches for obsolescence forecasting exist,they often require data that may not be available.This paper describes an approach using non-probabilistic scenarios coupled with decision analysis to investigate how particular scenarios influence priority setting for products and systems.Scenarios are generated from a list of emergent and future conditions related to obsolescence.The key result is an identification of the most and least disruptive scenarios to the decision maker’s priorities.An example is presented related to the selection of technologies for energy islanding,which demonstrates the methodology using six obsolescence scenarios.The paper should be of broad interest to scholars and practitioners engaged with enterprise risk management and similar challenges of large-scale systems.
文摘The burden of injuries is underestimated to an evengreater extent in developing countries than inindustrialized countries. The objective of this paper is toanalyze injuries and diseases in the monitored work place