Traffic intersections are incredibly dangerous for drivers and pedestrians. Statistics from both Canada and the U.S. show a high number of fatalities and serious injuries related to crashes at intersections. In Canada...Traffic intersections are incredibly dangerous for drivers and pedestrians. Statistics from both Canada and the U.S. show a high number of fatalities and serious injuries related to crashes at intersections. In Canada, during 2019, the National Collision Database shows that 28% of traffic fatalities and 42% of serious injuries occurred at intersections. Likewise, the U.S. National Highway Traffic Administration (NHTSA) found that about 40% of the estimated 5,811,000 accidents in the U.S. during the year studied were intersection-related crashes. In fact, a major survey by the car insurance industry found that nearly 85% of drivers could not identify the correct action to take when approaching a yellow traffic light at an intersection. One major reason for these accidents is the “yellow light dilemma,” the ambiguous situation where a driver should stop or proceed forward when unexpectedly faced with a yellow light. This situation is even further exacerbated by the tendency of aggressive drivers to inappropriately speed up on the yellow just to get through the traffic light. A survey of Canadian drivers conducted by the Traffic Injury Research Foundation found that 9% of drivers admitted to speeding up to get through a traffic light. Another reason for these accidents is the increased danger of making a left-hand turn on yellow. According to the National Highway Traffic Safety Association (NHTSA), left turns occur in approximately 22.2% of collisions—as opposed to just 1.2% for right turns. Moreover, a study by CNN found left turns are three times as likely to kill pedestrians than right turns. The reason left turns are so much more likely to cause an accident is because they take a driver against traffic and in the path of oncoming cars. Additionally, most of these left turns occur at the driver’s discretion—as opposed to the distressingly brief left-hand arrow at busy intersections. Drive Safe Now proposes a workable solution for reducing the number of accidents occurring during a yellow light at intersections. We believe this fairly simple solution will save lives, prevent injuries, reduce damage to public and private property, and decrease insurance costs.展开更多
Classical Mechanics using Einstein’s theories of relativity places a limit on speed as the speed of light. Quantum Mechanics has no such limitation. To understand space accelerating faster than the speed of light and...Classical Mechanics using Einstein’s theories of relativity places a limit on speed as the speed of light. Quantum Mechanics has no such limitation. To understand space accelerating faster than the speed of light and information being exchanged instantaneously between two entangled electrons separated by huge distances, one uses Planck’s length, Planck’s time, and Planck’s mass to indicate that space and time are discrete and therefore along with masses smaller than Planck’s mass are Quantum Mechanical in nature. Faster than the speed of light c = 3 × 10<sup>8</sup> m/s is a classical effect only in dimensions of space lower than our 3-D Universe, but it is a Quantum effect in all dimensions of space. Because space can oscillate sending out ripples from the source, it is the medium used for transporting light waves and gravity waves.展开更多
Starting from the basic assumptions and equations of Big Bang theory, we present a simple mathematical proof that this theory implies a varying (decreasing) speed of light, contrary to what is generally accepted. We c...Starting from the basic assumptions and equations of Big Bang theory, we present a simple mathematical proof that this theory implies a varying (decreasing) speed of light, contrary to what is generally accepted. We consider General Relativity, the first Friedmann equation and the Friedmann-Lema?tre- Robertson-Walker (FLRW) metric for a Comoving Observer. It is shown explicitly that the Horizon and Flatness Problems are solved, taking away an important argument for the need of Cosmic Inflation. A decrease of 2.1 cm/s per year of the present-day speed of light is predicted. This is consistent with the observed acceleration of the expansion of the Universe, as determined from high-redshift supernova data. The calculation does not use any quantum processes, and no adjustable parameters or fine tuning are introduced. It is argued that more precise laboratory measurements of the present-day speed of light (and its evolution) should be carried out. Also it is argued that the combination of the FLRW metric and Einstein’s field equations of General Relativity is inconsistent, because the FLRW metric implies a variable speed of light, and Einstein’s field equations use a constant speed of light. If we accept standard Big Bang theory (and thus the combination of General Relativity and the FLRW metric), a variable speed of light must be allowed in the Friedmann equation, and therefore also, more generally, in Einstein’s field equations of General Relativity. The explicit form of this time dependence will then be determined by the specific problem.展开更多
The paper presents a detailed analysis of ordinary and dark energy density of the cosmos based on two different but complimentary theories. First, and starting from the concept of the speed of light being an average o...The paper presents a detailed analysis of ordinary and dark energy density of the cosmos based on two different but complimentary theories. First, and starting from the concept of the speed of light being an average over multi-fractals, we use Magueijo-Smolin’s ingenious revision of Einstein’s special relativity famous formula E = mc2 to a doubly special formula which includes the Planck energy as invariant to derive the ordinary energy density E(O) = mc2/22 and the dark energy density E(D) = mc2(21/22) wheremis the mass andcis the speed of light. Second we use the topological theory of pure gravity to reach the same result thus confirming the correctness of the theory of varying speed of light as well as the COBE, WMAP and Type 1a supernova cosmological measurements.展开更多
Endoplasmic reticulum stress and mitochondrial dysfunction play important roles in Parkinson s disease,but the regulato ry mechanism remains elusive.Prohibitin-2(PHB2)is a newly discove red autophagy receptor in the m...Endoplasmic reticulum stress and mitochondrial dysfunction play important roles in Parkinson s disease,but the regulato ry mechanism remains elusive.Prohibitin-2(PHB2)is a newly discove red autophagy receptor in the mitochondrial inner membrane,and its role in Parkinson’s disease remains unclear.Protein kinase R(PKR)-like endoplasmic reticulum kinase(PERK)is a factor that regulates cell fate during endoplasmic reticulum stress.Parkin is regulated by PERK and is a target of the unfolded protein response.It is unclear whether PERK regulates PHB2-mediated mitophagy thro ugh Parkin.In this study,we established a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-induced mouse model of Parkinson’s disease.We used adeno-associated virus to knockdown PHB2 expression.Our res ults showed that loss of dopaminergic neurons and motor deficits were aggravated in the MPTP-induced mouse model of Parkinson’s disease.Ove rexpression of PHB2 inhibited these abnormalities.We also established a 1-methyl-4-phenylpyridine(MPP+)-induced SH-SY5Y cell model of Parkinson’s disease.We found that ove rexpression of Parkin increased co-localization of PHB2 and microtubule-associated protein 1 light chain 3,and promoted mitophagy.In addition,MPP+regulated Parkin involvement in PHB2-mediated mitophagy through phosphorylation of PERK.These findings suggest that PHB2 participates in the development of Parkinson’s disease by intera cting with endoplasmic reticulum stress and Parkin.展开更多
This thesis puts forward a conjecture that, owing to some unknown special character of light, it is impossible to determine whether the speed of light is variable by the interference method. To verify the hypothesis ...This thesis puts forward a conjecture that, owing to some unknown special character of light, it is impossible to determine whether the speed of light is variable by the interference method. To verify the hypothesis of the invariance of light speed, a new method must be found to take accurate measurement of the infinitesimal change in the travelling time of light. The thesis suggests the adoption of high frequency laser pulse technology to carry out the measurement. On the basis of this idea a new discriminating experiment is proposed to test the hypothesis of the invariance of light speed. The thesis also makes some forecast of the future prospects of this experiment and of the future development of the theory of special relativity.展开更多
In this paper we recall the different definitions of simultaneity, the coordinate time interval and the velocity. It is emphasized that the above second two definitions depend on the simultaneity. We review the test t...In this paper we recall the different definitions of simultaneity, the coordinate time interval and the velocity. It is emphasized that the above second two definitions depend on the simultaneity. We review the test theories on special relativity. It is shown that anisotropy (if possible) of one-way speed of light has not any ef- fects in the physical experiments. Therefore anisotropy of one-way speed of light cannot be determined by the experiments, except if an absolute (standard) simultaneity would be found.展开更多
Although the formula of mass-energy equivalence was derived from the hypothesis that the speed of light in free space is constant, conversely, the purpose of this research is to show that a method of probabilistically...Although the formula of mass-energy equivalence was derived from the hypothesis that the speed of light in free space is constant, conversely, the purpose of this research is to show that a method of probabilistically determining whether the speed of light is constant is derived from this formula. By considering the formula of mass-energy equivalence to be a function of the energy of an object moving at speed V, the probability density function (PDF) of the energy can be obtained using the inverse function of this formula, if the speed of light obeys a probability distribution. The main result is that the PDF of the energy diverges to infinity at a certain energy value regardless of the PDF of the speed of light. Thus, when the speed calculated from this value enters a certain range of the speed of light as V increases stepwise from below 299,792,458 m/s, the PDF of the energy should increase abruptly. If not, then the speed of light is constant. This is the method of probabilistically determining whether the speed of light is constant. An experimental method is proposed to confirm this.展开更多
We show how one can measure the speed of gravity only using gravitational phenomena. Our approach offers several ways to measure the speed of gravity (light) and checks existing assumptions about light (gravity) in ne...We show how one can measure the speed of gravity only using gravitational phenomena. Our approach offers several ways to measure the speed of gravity (light) and checks existing assumptions about light (gravity) in new types of experiments. The speed of light is included in several well-known gravitational formulas. However, if we can measure this speed from gravitational phenomena alone, then is it the speed of light or the speed of gravity we are measuring? We think it is more than a mere coincidence that they are the same. In addition, even if it is not possible to draw strong conclusions now, our formulations support the view that there is a link between electromagnetism and gravity. This paper also shows that all major gravity phenomena can be predicted from only performing two to three light observations. There is no need for knowledge of Newton’s gravitational constant G or the mass size to complete a series of major gravity predictions.展开更多
We show that as the dimensions of the Multiverse increase so does its density. This increase in density has the effect of decreasing the speed of light, slowing down time, and increasing the life span of each higher d...We show that as the dimensions of the Multiverse increase so does its density. This increase in density has the effect of decreasing the speed of light, slowing down time, and increasing the life span of each higher dimension and the life span of human beings occupying that higher dimension. We use the tenth dimension as the highest dimension as a special case but show that it is not possible to exactly determine its value because of varying factors that can end the Multiverse, sending all the Energy back into the original levels of the Quantum of the void that started the creation process.展开更多
We previously revealed a quantitative relation by which the fine-structure constant α can be described by the temperature T of cosmic microwave background (CMB) with several other fundamental constants, including the...We previously revealed a quantitative relation by which the fine-structure constant α can be described by the temperature T of cosmic microwave background (CMB) with several other fundamental constants, including the elementary charge e, the Boltzmann constant k, the Planck constant h, and the light of speed in vacuum c. Given that the value of α is quite conserved but T is variable across CMBs, we propose that c changes with T and can be given by T, the present CMB temperature T<sub>0</sub> and the present light speed c<sub>0</sub>. As T is continuously decreasing, c is thus predicted to decrease at a rate of ~2.15 centimeters/second (cm/s) per year. Moreover, we provide a lot of evidence to support this finding. In conclusion, this study suggests a possibility of variable speed of light in vacuum.展开更多
文摘Traffic intersections are incredibly dangerous for drivers and pedestrians. Statistics from both Canada and the U.S. show a high number of fatalities and serious injuries related to crashes at intersections. In Canada, during 2019, the National Collision Database shows that 28% of traffic fatalities and 42% of serious injuries occurred at intersections. Likewise, the U.S. National Highway Traffic Administration (NHTSA) found that about 40% of the estimated 5,811,000 accidents in the U.S. during the year studied were intersection-related crashes. In fact, a major survey by the car insurance industry found that nearly 85% of drivers could not identify the correct action to take when approaching a yellow traffic light at an intersection. One major reason for these accidents is the “yellow light dilemma,” the ambiguous situation where a driver should stop or proceed forward when unexpectedly faced with a yellow light. This situation is even further exacerbated by the tendency of aggressive drivers to inappropriately speed up on the yellow just to get through the traffic light. A survey of Canadian drivers conducted by the Traffic Injury Research Foundation found that 9% of drivers admitted to speeding up to get through a traffic light. Another reason for these accidents is the increased danger of making a left-hand turn on yellow. According to the National Highway Traffic Safety Association (NHTSA), left turns occur in approximately 22.2% of collisions—as opposed to just 1.2% for right turns. Moreover, a study by CNN found left turns are three times as likely to kill pedestrians than right turns. The reason left turns are so much more likely to cause an accident is because they take a driver against traffic and in the path of oncoming cars. Additionally, most of these left turns occur at the driver’s discretion—as opposed to the distressingly brief left-hand arrow at busy intersections. Drive Safe Now proposes a workable solution for reducing the number of accidents occurring during a yellow light at intersections. We believe this fairly simple solution will save lives, prevent injuries, reduce damage to public and private property, and decrease insurance costs.
文摘Classical Mechanics using Einstein’s theories of relativity places a limit on speed as the speed of light. Quantum Mechanics has no such limitation. To understand space accelerating faster than the speed of light and information being exchanged instantaneously between two entangled electrons separated by huge distances, one uses Planck’s length, Planck’s time, and Planck’s mass to indicate that space and time are discrete and therefore along with masses smaller than Planck’s mass are Quantum Mechanical in nature. Faster than the speed of light c = 3 × 10<sup>8</sup> m/s is a classical effect only in dimensions of space lower than our 3-D Universe, but it is a Quantum effect in all dimensions of space. Because space can oscillate sending out ripples from the source, it is the medium used for transporting light waves and gravity waves.
文摘Starting from the basic assumptions and equations of Big Bang theory, we present a simple mathematical proof that this theory implies a varying (decreasing) speed of light, contrary to what is generally accepted. We consider General Relativity, the first Friedmann equation and the Friedmann-Lema?tre- Robertson-Walker (FLRW) metric for a Comoving Observer. It is shown explicitly that the Horizon and Flatness Problems are solved, taking away an important argument for the need of Cosmic Inflation. A decrease of 2.1 cm/s per year of the present-day speed of light is predicted. This is consistent with the observed acceleration of the expansion of the Universe, as determined from high-redshift supernova data. The calculation does not use any quantum processes, and no adjustable parameters or fine tuning are introduced. It is argued that more precise laboratory measurements of the present-day speed of light (and its evolution) should be carried out. Also it is argued that the combination of the FLRW metric and Einstein’s field equations of General Relativity is inconsistent, because the FLRW metric implies a variable speed of light, and Einstein’s field equations use a constant speed of light. If we accept standard Big Bang theory (and thus the combination of General Relativity and the FLRW metric), a variable speed of light must be allowed in the Friedmann equation, and therefore also, more generally, in Einstein’s field equations of General Relativity. The explicit form of this time dependence will then be determined by the specific problem.
文摘The paper presents a detailed analysis of ordinary and dark energy density of the cosmos based on two different but complimentary theories. First, and starting from the concept of the speed of light being an average over multi-fractals, we use Magueijo-Smolin’s ingenious revision of Einstein’s special relativity famous formula E = mc2 to a doubly special formula which includes the Planck energy as invariant to derive the ordinary energy density E(O) = mc2/22 and the dark energy density E(D) = mc2(21/22) wheremis the mass andcis the speed of light. Second we use the topological theory of pure gravity to reach the same result thus confirming the correctness of the theory of varying speed of light as well as the COBE, WMAP and Type 1a supernova cosmological measurements.
基金supported by the Key Science and Technology Research of Henan Province,No.222102310351(to JW)Luoyang 2022 Medical and Health Guiding Science and Technology Plan Project,No.2022057Y(to JY)Henan Medical Science and Technology Research Program Province-Ministry Co-sponsorship,No.SBGJ202002099(to JY)。
文摘Endoplasmic reticulum stress and mitochondrial dysfunction play important roles in Parkinson s disease,but the regulato ry mechanism remains elusive.Prohibitin-2(PHB2)is a newly discove red autophagy receptor in the mitochondrial inner membrane,and its role in Parkinson’s disease remains unclear.Protein kinase R(PKR)-like endoplasmic reticulum kinase(PERK)is a factor that regulates cell fate during endoplasmic reticulum stress.Parkin is regulated by PERK and is a target of the unfolded protein response.It is unclear whether PERK regulates PHB2-mediated mitophagy thro ugh Parkin.In this study,we established a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine(MPTP)-induced mouse model of Parkinson’s disease.We used adeno-associated virus to knockdown PHB2 expression.Our res ults showed that loss of dopaminergic neurons and motor deficits were aggravated in the MPTP-induced mouse model of Parkinson’s disease.Ove rexpression of PHB2 inhibited these abnormalities.We also established a 1-methyl-4-phenylpyridine(MPP+)-induced SH-SY5Y cell model of Parkinson’s disease.We found that ove rexpression of Parkin increased co-localization of PHB2 and microtubule-associated protein 1 light chain 3,and promoted mitophagy.In addition,MPP+regulated Parkin involvement in PHB2-mediated mitophagy through phosphorylation of PERK.These findings suggest that PHB2 participates in the development of Parkinson’s disease by intera cting with endoplasmic reticulum stress and Parkin.
文摘This thesis puts forward a conjecture that, owing to some unknown special character of light, it is impossible to determine whether the speed of light is variable by the interference method. To verify the hypothesis of the invariance of light speed, a new method must be found to take accurate measurement of the infinitesimal change in the travelling time of light. The thesis suggests the adoption of high frequency laser pulse technology to carry out the measurement. On the basis of this idea a new discriminating experiment is proposed to test the hypothesis of the invariance of light speed. The thesis also makes some forecast of the future prospects of this experiment and of the future development of the theory of special relativity.
文摘In this paper we recall the different definitions of simultaneity, the coordinate time interval and the velocity. It is emphasized that the above second two definitions depend on the simultaneity. We review the test theories on special relativity. It is shown that anisotropy (if possible) of one-way speed of light has not any ef- fects in the physical experiments. Therefore anisotropy of one-way speed of light cannot be determined by the experiments, except if an absolute (standard) simultaneity would be found.
文摘Although the formula of mass-energy equivalence was derived from the hypothesis that the speed of light in free space is constant, conversely, the purpose of this research is to show that a method of probabilistically determining whether the speed of light is constant is derived from this formula. By considering the formula of mass-energy equivalence to be a function of the energy of an object moving at speed V, the probability density function (PDF) of the energy can be obtained using the inverse function of this formula, if the speed of light obeys a probability distribution. The main result is that the PDF of the energy diverges to infinity at a certain energy value regardless of the PDF of the speed of light. Thus, when the speed calculated from this value enters a certain range of the speed of light as V increases stepwise from below 299,792,458 m/s, the PDF of the energy should increase abruptly. If not, then the speed of light is constant. This is the method of probabilistically determining whether the speed of light is constant. An experimental method is proposed to confirm this.
文摘We show how one can measure the speed of gravity only using gravitational phenomena. Our approach offers several ways to measure the speed of gravity (light) and checks existing assumptions about light (gravity) in new types of experiments. The speed of light is included in several well-known gravitational formulas. However, if we can measure this speed from gravitational phenomena alone, then is it the speed of light or the speed of gravity we are measuring? We think it is more than a mere coincidence that they are the same. In addition, even if it is not possible to draw strong conclusions now, our formulations support the view that there is a link between electromagnetism and gravity. This paper also shows that all major gravity phenomena can be predicted from only performing two to three light observations. There is no need for knowledge of Newton’s gravitational constant G or the mass size to complete a series of major gravity predictions.
文摘We show that as the dimensions of the Multiverse increase so does its density. This increase in density has the effect of decreasing the speed of light, slowing down time, and increasing the life span of each higher dimension and the life span of human beings occupying that higher dimension. We use the tenth dimension as the highest dimension as a special case but show that it is not possible to exactly determine its value because of varying factors that can end the Multiverse, sending all the Energy back into the original levels of the Quantum of the void that started the creation process.
文摘We previously revealed a quantitative relation by which the fine-structure constant α can be described by the temperature T of cosmic microwave background (CMB) with several other fundamental constants, including the elementary charge e, the Boltzmann constant k, the Planck constant h, and the light of speed in vacuum c. Given that the value of α is quite conserved but T is variable across CMBs, we propose that c changes with T and can be given by T, the present CMB temperature T<sub>0</sub> and the present light speed c<sub>0</sub>. As T is continuously decreasing, c is thus predicted to decrease at a rate of ~2.15 centimeters/second (cm/s) per year. Moreover, we provide a lot of evidence to support this finding. In conclusion, this study suggests a possibility of variable speed of light in vacuum.
