he use of an absorption trap off-line two-dimensional gas chromatography (2-DGC) in conjunction with a mass spectrometer greatly improved the separation andidefitification of minor constituents of a complex mixture su...he use of an absorption trap off-line two-dimensional gas chromatography (2-DGC) in conjunction with a mass spectrometer greatly improved the separation andidefitification of minor constituents of a complex mixture such as a natural essentialoil. The absorption trap device used as an interface of 2-DGC offered the advantageof convenient manipulation.展开更多
A space-resolved EUV spectrometer for measuring the one-dimensional distribution of impurity line emissions in Large Helical Device (LHD) has been upgraded to measure two- dimensional distributions of impurity line ...A space-resolved EUV spectrometer for measuring the one-dimensional distribution of impurity line emissions in Large Helical Device (LHD) has been upgraded to measure two- dimensional distributions of impurity line emissions with an extension of working wavelength range to 30-650% The two-dimensional measurement is performed by scanning the observation chord horizontally. A rectangular plasma region of 520 × 700 mm2 in vertical and horizontal sizes can be observed during a single horizontal scan. The horizontal scan requires a time duration of 5 s at least. The spatial resolution is 10 mm in the vertical direction when a spatial-resolution slit of 0.2 mm in width is adopted. Although a spatial resolution in the toroidal direction is 75 mm, it is a function of CCD exposure time and horizontal scanning speed. Two-dimensional distribution of EUV line emissions from several impurities has been successfully observed for the first time from steady discharges in LHD. In this paper two-dimensional distributions of He II (303.78A), C V (40.27A), C VI (33.73A) and Fe XX (132.85A) located at different radial positions are presented with simple analysis on the magnetic field structure of LHD.展开更多
Objective To construct a database of human lung squamous carcinoma cell line NCI-H226 and to facilitate discovery of novel subtypes markers of lung cancer. Method Proteomic technique was used to analyze human lung squ...Objective To construct a database of human lung squamous carcinoma cell line NCI-H226 and to facilitate discovery of novel subtypes markers of lung cancer. Method Proteomic technique was used to analyze human lung squamous carcinoma cell line NCI-H226. The proteins of the NCI-H226 cells were separated by two-dimensional gel electrophoresis and identified by mass spectrometry. Results The results showed that a good reproducibility of the 2-D gel pattern was attained. The position deviation of matched spots among three 2-D gels was 1.95±0.53 mm in the isoelectric focusing direction, and 1.73±0.45 mm in the sodium dodecyl sulfate-polyacrylamide gel electrophoresis direction. One hundred and twenty-seven proteins, including enzymes, signal transduction proteins, structure proteins, transport proteins, etc. were characterized, of which, 29 identified proteins in NCI-H226 cells were reported for the first time to be involved in lung cancer carcinogenesis. Conclusion The information obtained from this study could provide some valuable clues for further study on the carcinogenetic mechanism of different types of lung cancer, and may help us to discover some potential subtype-specific biomarkers of lung cancer.展开更多
Using the twin shear stress yield criterion, the surface integral of the co-line vectors, and the integration depending on upper limit, Kobayashi's three-dimensional velocity field of rolling was analyzed and an anal...Using the twin shear stress yield criterion, the surface integral of the co-line vectors, and the integration depending on upper limit, Kobayashi's three-dimensional velocity field of rolling was analyzed and an analytical expression of rolling torque and single force was obtained. Through redoing the same experiment of rolling pure lead as Sims, the calculated results by the above expression were compared with those of Kobayashi and Sims formulae. The results show that the twin shear stress yield criterion is available for rolling analysis and the calculated results by the new formula are a little higher than those by Kobayashi and Sims ones if the reduction ratio is less than 30%.展开更多
A hierarchical scheme for clustering data is presented which applies to spaces with a high number of dimensions (). The data set is first reduced to a smaller set of partitions (multi-dimensional bins). Multiple clust...A hierarchical scheme for clustering data is presented which applies to spaces with a high number of dimensions (). The data set is first reduced to a smaller set of partitions (multi-dimensional bins). Multiple clustering techniques are used, including spectral clustering;however, new techniques are also introduced based on the path length between partitions that are connected to one another. A Line-of-Sight algorithm is also developed for clustering. A test bank of 12 data sets with varying properties is used to expose the strengths and weaknesses of each technique. Finally, a robust clustering technique is discussed based on reaching a consensus among the multiple approaches, overcoming the weaknesses found individually.展开更多
Background and Objective Cancer metastasis is not only the malignant characteristics of lung cancer, but also the key cause of failure to cure and high mortality. It has been proved
Phase-change line memory cells with different line widths are fabricated using focused-ion-beam deposited C-Pt as a hard mask. The electrical performance of these memory devices was characterized. The current^oltage ...Phase-change line memory cells with different line widths are fabricated using focused-ion-beam deposited C-Pt as a hard mask. The electrical performance of these memory devices was characterized. The current^oltage (I-V) and resistance-voltage (RV) characteristics demonstrate that the power consumption decreases with the width of the phase-change line. A three-dimensional simulation is carried out to further study the scaling properties of the phase- change line memory. The results show that the resistive amorphous (RESET) power consumption is proportional to the cross-sectional area of the phase-change line, but increases as the line length decreases.展开更多
In situ stress condition in rock mass is influenced by both tectonic activity and geological environment such as faulting and shearing in the rock mass.This influence is of significance in the Himalayan region,where t...In situ stress condition in rock mass is influenced by both tectonic activity and geological environment such as faulting and shearing in the rock mass.This influence is of significance in the Himalayan region,where the tectonic movement is active,resulting in periodic dynamic earthquakes.Each large-scale earthquake causes both accumulation and sudden release of strain energy,instigating changes in the in situ stress environment in the rock mass.This paper first highlights the importance of the magnitude of the minimum principal stress in the design of unlined or shotcrete lined pressure tunnel as water conveyance system used for hydropower schemes.Then we evaluated the influence of local shear faults on the magnitude of the minimum principal stress along the shotcrete lined high pressure tunnel of Upper Tamakoshi Hydroelectric Project(UTHP)in Nepal.A detailed assessment of the in situ stress state is carried out using both measured data and three-dimensional(3D)numerical analyses with FLAC3D.Finally,analysis is carried out on the possible changes in the magnitude of the minimum principal stress in the rock mass caused by seismic movement(dynamic loading).A permanent change in the stress state at and nearby the area of shear zones along the tunnel alignment is found to be an eminent process.展开更多
Using prospecting line profile map in combination with drilling and other information for 3D reconstruction of geological model is an important method of 3D geological modeling.?This paper?discusses the theory and imp...Using prospecting line profile map in combination with drilling and other information for 3D reconstruction of geological model is an important method of 3D geological modeling.?This paper?discusses the theory and implementation method of 2D prospecting line map into 3D prospecting line map and then into 3D model. The authors propose that it needs twice upgrading dimension to reconstruction 3D geology model from prospecting line profile map. The first upgrading dimension is to convert profile from 2D into 3D profile,?i.e.?the 2D points in the 2D profile map upgrading dimensional transformation to 3D points in a 3D profile. The second upgrading dimension is that transform 0D point 1D curve and 2D polygon feature into 1D curve, 2D surface and 3D solid feature. The paper reexamines contents and forms in prospecting line map from the two different viewpoints of geology and geographic information science. The process of 3D geology modeling from 2D prospecting map is summarized as follows. Firstly, profile is divided into several sections by beginning, end and drill point of the prospecting line. Next, a 3D folded upright profile frame is built by 2D folded prospecting line on the plan map. Then, 2D points of features on 2D profile are converted into 3D points on 3D profile section by section. And then, adding switch control points for the long line crossover two segments. Lastly, 1D curve features are upgraded to 2D surface.展开更多
The present paper introduces a three-dimensional guidance system developed for a miniature Autonomous Underwater Vehicle(AUV). The guidance system determines the best trajectory for the vehicle based on target behav...The present paper introduces a three-dimensional guidance system developed for a miniature Autonomous Underwater Vehicle(AUV). The guidance system determines the best trajectory for the vehicle based on target behavior and vehicle capabilities. The dynamic model of this novel AUV is derived based on its special characteristics such as the horizontal posture and the independent diving mechanism. To design the guidance strategy, the main idea is to select the desired depth, presumed proportional to the horizontal distance of the AUV and the target. By connecting the two with a straight line, this strategy helps the AUV move in a trajectory sufficiently close to this line. The adjacency of the trajectory to the line leads to reasonably short travelling distances and avoids unsafe areas. Autopilots are designed using sliding mode controller. Two different engagement geometries are considered to evaluate the strategy's performance: stationary target and moving target. The simulation results show that the strategy can provide sufficiently fast and smooth trajectories in both target situations.展开更多
This paper discusses the two-dimensional discrete monatomic Fermi- Pasta-Ulam lattice, by using the method of multiple-scale and the quasi-discreteness approach. By taking into account the interaction between the atom...This paper discusses the two-dimensional discrete monatomic Fermi- Pasta-Ulam lattice, by using the method of multiple-scale and the quasi-discreteness approach. By taking into account the interaction between the atoms in the lattice and their nearest neighbours, it obtains some classes of two-dimensional local models as follows: two-dimensional bright and dark discrete soliton trains, two-dimensional bright and dark line discrete breathers, and two-dimensional bright and dark discrete breather.展开更多
文摘he use of an absorption trap off-line two-dimensional gas chromatography (2-DGC) in conjunction with a mass spectrometer greatly improved the separation andidefitification of minor constituents of a complex mixture such as a natural essentialoil. The absorption trap device used as an interface of 2-DGC offered the advantageof convenient manipulation.
基金partially carried out under the LHD project financial support (NIFS12ULPP010)partly supported by the JSPS-NRF-NSFC A3 Foresight Program in the field of Plasma Physics (No. 11261140328)
文摘A space-resolved EUV spectrometer for measuring the one-dimensional distribution of impurity line emissions in Large Helical Device (LHD) has been upgraded to measure two- dimensional distributions of impurity line emissions with an extension of working wavelength range to 30-650% The two-dimensional measurement is performed by scanning the observation chord horizontally. A rectangular plasma region of 520 × 700 mm2 in vertical and horizontal sizes can be observed during a single horizontal scan. The horizontal scan requires a time duration of 5 s at least. The spatial resolution is 10 mm in the vertical direction when a spatial-resolution slit of 0.2 mm in width is adopted. Although a spatial resolution in the toroidal direction is 75 mm, it is a function of CCD exposure time and horizontal scanning speed. Two-dimensional distribution of EUV line emissions from several impurities has been successfully observed for the first time from steady discharges in LHD. In this paper two-dimensional distributions of He II (303.78A), C V (40.27A), C VI (33.73A) and Fe XX (132.85A) located at different radial positions are presented with simple analysis on the magnetic field structure of LHD.
基金This work was supported by the National Natural Science Foundation of China (Grant No.30370712)Beijing Key Project (Grant No. 7051002).
文摘Objective To construct a database of human lung squamous carcinoma cell line NCI-H226 and to facilitate discovery of novel subtypes markers of lung cancer. Method Proteomic technique was used to analyze human lung squamous carcinoma cell line NCI-H226. The proteins of the NCI-H226 cells were separated by two-dimensional gel electrophoresis and identified by mass spectrometry. Results The results showed that a good reproducibility of the 2-D gel pattern was attained. The position deviation of matched spots among three 2-D gels was 1.95±0.53 mm in the isoelectric focusing direction, and 1.73±0.45 mm in the sodium dodecyl sulfate-polyacrylamide gel electrophoresis direction. One hundred and twenty-seven proteins, including enzymes, signal transduction proteins, structure proteins, transport proteins, etc. were characterized, of which, 29 identified proteins in NCI-H226 cells were reported for the first time to be involved in lung cancer carcinogenesis. Conclusion The information obtained from this study could provide some valuable clues for further study on the carcinogenetic mechanism of different types of lung cancer, and may help us to discover some potential subtype-specific biomarkers of lung cancer.
基金ItemSponsored by National Natural Science Foundation of China (50474015)
文摘Using the twin shear stress yield criterion, the surface integral of the co-line vectors, and the integration depending on upper limit, Kobayashi's three-dimensional velocity field of rolling was analyzed and an analytical expression of rolling torque and single force was obtained. Through redoing the same experiment of rolling pure lead as Sims, the calculated results by the above expression were compared with those of Kobayashi and Sims formulae. The results show that the twin shear stress yield criterion is available for rolling analysis and the calculated results by the new formula are a little higher than those by Kobayashi and Sims ones if the reduction ratio is less than 30%.
文摘A hierarchical scheme for clustering data is presented which applies to spaces with a high number of dimensions (). The data set is first reduced to a smaller set of partitions (multi-dimensional bins). Multiple clustering techniques are used, including spectral clustering;however, new techniques are also introduced based on the path length between partitions that are connected to one another. A Line-of-Sight algorithm is also developed for clustering. A test bank of 12 data sets with varying properties is used to expose the strengths and weaknesses of each technique. Finally, a robust clustering technique is discussed based on reaching a consensus among the multiple approaches, overcoming the weaknesses found individually.
基金supported by the grants from the National Natural Science Foundation of ChinaScience Foundation of Sichuan University (No. 30070333 and No.200349)
文摘Background and Objective Cancer metastasis is not only the malignant characteristics of lung cancer, but also the key cause of failure to cure and high mortality. It has been proved
基金Project supported by the National Integrate Circuit Research Program of China (Grant No. 2009ZX02023-003)the National Key Basic Research Program of China (Grant Nos. 2010CB934300, 2011CBA00602, and 2011CB932800)+1 种基金the National Natural Science Foundation of China (Grant Nos. 60906003, 60906004, 61006087, and 61076121)the Science and Technology Council of Shanghai of China (Grant No. 1052nm07000)
文摘Phase-change line memory cells with different line widths are fabricated using focused-ion-beam deposited C-Pt as a hard mask. The electrical performance of these memory devices was characterized. The current^oltage (I-V) and resistance-voltage (RV) characteristics demonstrate that the power consumption decreases with the width of the phase-change line. A three-dimensional simulation is carried out to further study the scaling properties of the phase- change line memory. The results show that the resistive amorphous (RESET) power consumption is proportional to the cross-sectional area of the phase-change line, but increases as the line length decreases.
文摘In situ stress condition in rock mass is influenced by both tectonic activity and geological environment such as faulting and shearing in the rock mass.This influence is of significance in the Himalayan region,where the tectonic movement is active,resulting in periodic dynamic earthquakes.Each large-scale earthquake causes both accumulation and sudden release of strain energy,instigating changes in the in situ stress environment in the rock mass.This paper first highlights the importance of the magnitude of the minimum principal stress in the design of unlined or shotcrete lined pressure tunnel as water conveyance system used for hydropower schemes.Then we evaluated the influence of local shear faults on the magnitude of the minimum principal stress along the shotcrete lined high pressure tunnel of Upper Tamakoshi Hydroelectric Project(UTHP)in Nepal.A detailed assessment of the in situ stress state is carried out using both measured data and three-dimensional(3D)numerical analyses with FLAC3D.Finally,analysis is carried out on the possible changes in the magnitude of the minimum principal stress in the rock mass caused by seismic movement(dynamic loading).A permanent change in the stress state at and nearby the area of shear zones along the tunnel alignment is found to be an eminent process.
文摘Using prospecting line profile map in combination with drilling and other information for 3D reconstruction of geological model is an important method of 3D geological modeling.?This paper?discusses the theory and implementation method of 2D prospecting line map into 3D prospecting line map and then into 3D model. The authors propose that it needs twice upgrading dimension to reconstruction 3D geology model from prospecting line profile map. The first upgrading dimension is to convert profile from 2D into 3D profile,?i.e.?the 2D points in the 2D profile map upgrading dimensional transformation to 3D points in a 3D profile. The second upgrading dimension is that transform 0D point 1D curve and 2D polygon feature into 1D curve, 2D surface and 3D solid feature. The paper reexamines contents and forms in prospecting line map from the two different viewpoints of geology and geographic information science. The process of 3D geology modeling from 2D prospecting map is summarized as follows. Firstly, profile is divided into several sections by beginning, end and drill point of the prospecting line. Next, a 3D folded upright profile frame is built by 2D folded prospecting line on the plan map. Then, 2D points of features on 2D profile are converted into 3D points on 3D profile section by section. And then, adding switch control points for the long line crossover two segments. Lastly, 1D curve features are upgraded to 2D surface.
文摘The present paper introduces a three-dimensional guidance system developed for a miniature Autonomous Underwater Vehicle(AUV). The guidance system determines the best trajectory for the vehicle based on target behavior and vehicle capabilities. The dynamic model of this novel AUV is derived based on its special characteristics such as the horizontal posture and the independent diving mechanism. To design the guidance strategy, the main idea is to select the desired depth, presumed proportional to the horizontal distance of the AUV and the target. By connecting the two with a straight line, this strategy helps the AUV move in a trajectory sufficiently close to this line. The adjacency of the trajectory to the line leads to reasonably short travelling distances and avoids unsafe areas. Autopilots are designed using sliding mode controller. Two different engagement geometries are considered to evaluate the strategy's performance: stationary target and moving target. The simulation results show that the strategy can provide sufficiently fast and smooth trajectories in both target situations.
基金Project supported by the National Natural Science Foundation of China (Grant No 10574011)Natural Science Foundation of Heilongjiang Province,China (Grant No A200506)
文摘This paper discusses the two-dimensional discrete monatomic Fermi- Pasta-Ulam lattice, by using the method of multiple-scale and the quasi-discreteness approach. By taking into account the interaction between the atoms in the lattice and their nearest neighbours, it obtains some classes of two-dimensional local models as follows: two-dimensional bright and dark discrete soliton trains, two-dimensional bright and dark line discrete breathers, and two-dimensional bright and dark discrete breather.