Objective: To establish a new assay for platelet-activating factor (PAF), to compare it with bio-assay; and to discuss its significance in some elderly people diseases such as cerebral infarction and coronary heart di...Objective: To establish a new assay for platelet-activating factor (PAF), to compare it with bio-assay; and to discuss its significance in some elderly people diseases such as cerebral infarction and coronary heart disease. Methods: To measure PAF levels in 100 controls, 23 elderly patients with cerebral infarction and 65 cases with coronary heart disease by reversed phase high-performance liquid chromatographic technique (rHPLC). Results:rHPLC is more convenient, sensitive,specific, and less confusing, compared with bio-assay. The level of plasma PAF in patients with cerebral infarction was higher than that in the controls (P<0.01), and in patients with coronary heart disease. Conclusion: Detection of PAF with rHPLC is more reliable and more accurate. The new assay has important significance in PAF research.展开更多
Ti_(3)SiC_(2) ceramic and SUS430 ferritic stainless steel were welded by the transient liquid phase(TLP)diffusion bonding method using an Al interlayer at 850-1050℃ in vacuum.The evolution of phase and morphology at ...Ti_(3)SiC_(2) ceramic and SUS430 ferritic stainless steel were welded by the transient liquid phase(TLP)diffusion bonding method using an Al interlayer at 850-1050℃ in vacuum.The evolution of phase and morphology at the interface and bonding strength were systematically investigated.The results show that Ti_(3)SiC_(2) and SUS430 were well bonded at 900-950℃.Three reaction zones were observed at the interface.At the joint interface area adjacent to alloy,the alloy completely reacted with liquid Al to form Al_(86)Fe_(14).At Ti_(3)SiC_(2)/Al interface,Ti and Si diffused outward from Ti_(3)SiC_(2) into the molten Al to form Fe_(3)Al+Al_(5)FeSi+TiAl_(3) zone.Adjacent to Ti_(3)SiC_(2) matrix,Ti_(3)Si(Al)C_(2)+TiCx zone was formed by the loss of Si.The evolution mechanism of TLP-bonded joints was discussed based on the interface microstructure and product phases.In addition,the tensile strength of the joint increased with increasing bonding temperature.The corresponding maximum value of 59.7 MPa was obtained from SUS430/Al(10μm)/Ti_(3)SiC_(2) joint prepared at 950℃.展开更多
文摘Objective: To establish a new assay for platelet-activating factor (PAF), to compare it with bio-assay; and to discuss its significance in some elderly people diseases such as cerebral infarction and coronary heart disease. Methods: To measure PAF levels in 100 controls, 23 elderly patients with cerebral infarction and 65 cases with coronary heart disease by reversed phase high-performance liquid chromatographic technique (rHPLC). Results:rHPLC is more convenient, sensitive,specific, and less confusing, compared with bio-assay. The level of plasma PAF in patients with cerebral infarction was higher than that in the controls (P<0.01), and in patients with coronary heart disease. Conclusion: Detection of PAF with rHPLC is more reliable and more accurate. The new assay has important significance in PAF research.
基金supported by the National Natural Science Foundation of China(No.52001179)Natural Science Foundation of Shandong Province,China(No.ZR2020ME019).
文摘Ti_(3)SiC_(2) ceramic and SUS430 ferritic stainless steel were welded by the transient liquid phase(TLP)diffusion bonding method using an Al interlayer at 850-1050℃ in vacuum.The evolution of phase and morphology at the interface and bonding strength were systematically investigated.The results show that Ti_(3)SiC_(2) and SUS430 were well bonded at 900-950℃.Three reaction zones were observed at the interface.At the joint interface area adjacent to alloy,the alloy completely reacted with liquid Al to form Al_(86)Fe_(14).At Ti_(3)SiC_(2)/Al interface,Ti and Si diffused outward from Ti_(3)SiC_(2) into the molten Al to form Fe_(3)Al+Al_(5)FeSi+TiAl_(3) zone.Adjacent to Ti_(3)SiC_(2) matrix,Ti_(3)Si(Al)C_(2)+TiCx zone was formed by the loss of Si.The evolution mechanism of TLP-bonded joints was discussed based on the interface microstructure and product phases.In addition,the tensile strength of the joint increased with increasing bonding temperature.The corresponding maximum value of 59.7 MPa was obtained from SUS430/Al(10μm)/Ti_(3)SiC_(2) joint prepared at 950℃.
