In this paper, we study the flocking behavior of a thermodynamic Cucker–Smale model with local velocity interactions. Using the spectral gap of a connected stochastic matrix, together with an elaborate estimate on pe...In this paper, we study the flocking behavior of a thermodynamic Cucker–Smale model with local velocity interactions. Using the spectral gap of a connected stochastic matrix, together with an elaborate estimate on perturbations of a linearized system, we provide a sufficient framework in terms of initial data and model parameters to guarantee flocking. Moreover, it is shown that the system achieves a consensus at an exponential rate.展开更多
In this paper,we consider the Chan–Vese(C-V)model for image segmentation and obtain its numerical solution accurately and efficiently.For this purpose,we present a local radial basis function method based on a Gaussi...In this paper,we consider the Chan–Vese(C-V)model for image segmentation and obtain its numerical solution accurately and efficiently.For this purpose,we present a local radial basis function method based on a Gaussian kernel(GA-LRBF)for spatial discretization.Compared to the standard radial basis functionmethod,this approach consumes less CPU time and maintains good stability because it uses only a small subset of points in the whole computational domain.Additionally,since the Gaussian function has the property of dimensional separation,the GA-LRBF method is suitable for dealing with isotropic images.Finally,a numerical scheme that couples GA-LRBF with the fourth-order Runge–Kutta method is applied to the C-V model,and a comparison of some numerical results demonstrates that this scheme achieves much more reliable image segmentation.展开更多
Spatio-temporal variability and dynamics in Sahelian agro-pastoral zones make each local situation a special case. These specificities must be considered to guide the dissemination of agricultural options with a view ...Spatio-temporal variability and dynamics in Sahelian agro-pastoral zones make each local situation a special case. These specificities must be considered to guide the dissemination of agricultural options with a view to sustainable development. The territorial scale of municipalities is not sufficient for this necessary contextualization;the scale of the “village terroir” seems to be a better option. This is the hypothesis we put forward in the framework of the Global Collaboration for Resilient Food Systems program (CRFS), i.e. local context is spatially defined by village terroir. The study is based on data collected through participatory mapping and surveys in “village terroirs” in three regions of Niger (Maradi, Dosso and Tillabéri). Then the links between farm managers and their cultivated land, as well as the spatio-temporal dynamics of local context are analyzed. This study provides evidence of the existence and functional usefulness of the village terroir for farmers, their land management and their activities. It demonstrates the usefulness of contextualizing agricultural options at this scale. Their analysis elucidates the links between “terroirs village” and the specific functioning of the agrosocio-ecosystems acting on each of them, thus laying the systemic and geographical foundations for a model of the spatio- temporal dynamics of “village terroirs”. This initial work has opened up new perspectives in modeling and sustainable development.展开更多
In this paper,we prove the local existence and uniqueness of solutions to the evolutionary model for magnetoviscoelasticity in R^(2),R^(3).This model consists of an incompressible Navier-Stokes,a regularized system fo...In this paper,we prove the local existence and uniqueness of solutions to the evolutionary model for magnetoviscoelasticity in R^(2),R^(3).This model consists of an incompressible Navier-Stokes,a regularized system for the evolution of the deformation gradient and the Landau-Lifshitz-Gilbert system for the dynamics of the mag-netization.Our approach depends on approximating the system with a sequence of perturbed systems.展开更多
In this paper,we explore bound preserving and high-order accurate local discontinuous Galerkin(LDG)schemes to solve a class of chemotaxis models,including the classical Keller-Segel(KS)model and two other density-depe...In this paper,we explore bound preserving and high-order accurate local discontinuous Galerkin(LDG)schemes to solve a class of chemotaxis models,including the classical Keller-Segel(KS)model and two other density-dependent problems.We use the convex splitting method,the variant energy quadratization method,and the scalar auxiliary variable method coupled with the LDG method to construct first-order temporal accurate schemes based on the gradient flow structure of the models.These semi-implicit schemes are decoupled,energy stable,and can be extended to high accuracy schemes using the semi-implicit spectral deferred correction method.Many bound preserving DG discretizations are only worked on explicit time integration methods and are difficult to get high-order accuracy.To overcome these difficulties,we use the Lagrange multipliers to enforce the implicit or semi-implicit LDG schemes to satisfy the bound constraints at each time step.This bound preserving limiter results in the Karush-Kuhn-Tucker condition,which can be solved by an efficient active set semi-smooth Newton method.Various numerical experiments illustrate the high-order accuracy and the effect of bound preserving.展开更多
Active shape models (ASM), consisting of a shape model and a local gray-level appearance model, can be used to locate the objects in images. In original ASM scheme, the model of object′s gray-level variations is base...Active shape models (ASM), consisting of a shape model and a local gray-level appearance model, can be used to locate the objects in images. In original ASM scheme, the model of object′s gray-level variations is based on the assumption of one-dimensional sampling and searching method. In this work a new way to model the gray-level appearance of the objects is explored, using a two-dimensional sampling and searching technique in a rectangular area around each landmark of object shape. The ASM based on this improvement is compared with the original ASM on an identical medical image set for task of spine localization. Experiments demonstrate that the method produces significantly fast, effective, accurate results for spine localization in medical images.展开更多
By using the widely used JOHNSON-COOK model and the gradient-dependent plasticity to consider microstructural effect beyond the occurrence of shear strain localization,the distributions of local plastic shear strain a...By using the widely used JOHNSON-COOK model and the gradient-dependent plasticity to consider microstructural effect beyond the occurrence of shear strain localization,the distributions of local plastic shear strain and deformation in adiabatic shear band(ASB)were analyzed.The peak local plastic shear strain is proportional to the average plastic shear strain,while it is inversely proportional to the critical plastic shear strain corresponding to the peak flow shear stress.The relative plastic shear deformation between the top and base of ASB depends on the thickness of ASB and the average plastic shear strain.A parametric study was carried out to study the influence of constitutive parameters on shear strain localization.Higher values of static shear strength and work to heat conversion factor lead to lower critical plastic shear strain so that the shear localization is more apparent at the same average plastic shear strain.Higher values of strain-hardening exponent,strain rate sensitive coefficient,melting point,thermal capacity and mass density result in higher critical plastic shear strain,leading to less apparent shear localization at the same average plastic shear strain.The strain rate sensitive coefficient has a minor influence on the critical plastic shear strain,the distributions of local plastic shear strain and deformation in ASB.The effect of strain-hardening modulus on the critical plastic shear strain is not monotonous.When the maximum critical plastic shear strain is reached,the least apparent shear localization occurs.展开更多
The mechanism of local scour around submarine pipelines is studied numerically based on a renormalized group (RNG) turbulence model. To validate the numerical model, the equilibrium profiles of local scour for two c...The mechanism of local scour around submarine pipelines is studied numerically based on a renormalized group (RNG) turbulence model. To validate the numerical model, the equilibrium profiles of local scour for two cases are simulated and compared with the experimental data. It shows that the RNG turbulence model can give an appropriate prediction for the configuration of equilibrium scour hole, and it is applicable to this situation. The local scour mechanism around submarine pipelines including the flow structure, shear stress distribution and pressure field is then analyzed and compared with experiments. For further comparison and validation, especially for the flow structure, a numerical calculation employing the large eddy simulation (LES) is also conducted. The numerical results of RNG demonstrate that the critical factor governing the equilibrium profile is the seabed shear stress distribution in the case of bed load sediment transport, and the two-equation RNG turbulence model coupled with the law of wall is capable of giving a satisfying estimation for the bed shear stress. Moreover, the piping phenomena due to the great difference of pressure between the upstream and downstream parts of pipelines and the vortex structure around submarine pipelines are also simulated successfully, which are believed to be the important factor that lead to the onset of local scour.展开更多
Periodontitis is an inflammatory autoimmune disease. Treatment should alleviate inflammation, regulate the immune reaction and promote periodontal tissue regeneration. Icariin is the main active ingredient of Epimedii...Periodontitis is an inflammatory autoimmune disease. Treatment should alleviate inflammation, regulate the immune reaction and promote periodontal tissue regeneration. Icariin is the main active ingredient of Epimedii Folium, and it is a promising compound for the enhancement of mesenchymal stem cell function, promotion of bone formation, inhibition of bone resorption, alleviation of inflammation and regulation of immunity. The study investigated the effect of icariin on periodontal tissue regeneration in a minipig model of periodontitis. The minipig model of periodontitis was established. Icariin was injected locally. The periodontal clinical assessment index, a computed tomography(CT) scan, histopathology and enzyme-linked immune sorbent assay(ELISA)were used to evaluate the effects of icariin. Quantitative analysis results 12 weeks post-injection demonstrated that probing depth,gingival recession, attachment loss and alveolar bone regeneration values were(3.72 ± 1.18) mm vs.(6.56 ± 1.47) mm,(1.67 ± 0.59)mm vs.(2.38 ± 0.61) mm,(5.56 ± 1.29) mm vs.(8.61 ± 1.72) mm, and(25.65 ± 5.13) mm3 vs.(9.48 ± 1.78) mm3 in the icariin group and0.9% NaCl group, respectively. The clinical assessment, CT scan, and histopathology results demonstrated significant enhancement of periodontal tissue regeneration in the icariin group compared to the 0.9% NaCl group. The ELISA results suggested that the concentration of interleukin-1 beta(IL-1β) in the icariin group was downregulated compared to the 0.9% NaCl group, which indicates that local injection of icariin relieved local inflammation in a minipig model of periodontitis. Local injection of icariin promoted periodontal tissue regeneration and exerted anti-inflammatory and immunomodulatory function. These results support the application of icariin for the clinical treatment of periodontitis.展开更多
Employing an ideal elasto-plastic model,the typically used strength reduction method reduced the strength of all soil elements of a slope.Therefore,this method was called the global strength reduction method(GSRM).How...Employing an ideal elasto-plastic model,the typically used strength reduction method reduced the strength of all soil elements of a slope.Therefore,this method was called the global strength reduction method(GSRM).However,the deformation field obtained by GSRM could not reflect the real deformation of a slope when the slope became unstable.For most slopes,failure occurs once the strength of some regional soil is sufficiently weakened; thus,the local strength reduction method(LSRM)was proposed to analyze slope stability.In contrast with GSRM,LSRM only reduces the strength of local soil,while the strength of other soil remains unchanged.Therefore,deformation by LSRM is more reasonable than that by GSRM.In addition,the accuracy of the slope's deformation depends on the constitutive model to a large degree,and the variable-modulus elasto-plastic model was thus adopted.This constitutive model was an improvement of the Duncan–Chang model,which modified soil's deformation modulus according to stress level,and it thus better reflected the plastic feature of soil.Most importantly,the parameters of the variable-modulus elasto-plastic model could be determined through in-situ tests,and parameters determination by plate loading test and pressuremeter test were introduced.Therefore,it is easy to put this model into practice.Finally,LSRM and the variable-modulus elasto-plastic model were used to analyze Egongdai ancient landslide.Safety factor,deformation field,and optimal reinforcement measures for Egongdai ancient landslide were obtained based on the proposed method.展开更多
In this article, authors introduce a method to assess local influence of obser- vations on the parameter estimates and prediction in multivariate regression model. The diagnostics under the perturbations of error vari...In this article, authors introduce a method to assess local influence of obser- vations on the parameter estimates and prediction in multivariate regression model. The diagnostics under the perturbations of error variance, response variables and explanatory variables are derived, and the results are compared with those of case- deletion. Two examples are analyzed for illustration.展开更多
In order to examine the effectiveness of engineering protection against localized scour in front of the south groin-group of the Yangtze Estuary Waterway Improvement Project, Phase I , an undistort-ed physical model o...In order to examine the effectiveness of engineering protection against localized scour in front of the south groin-group of the Yangtze Estuary Waterway Improvement Project, Phase I , an undistort-ed physical model on a geometric scale of 1:250 is built in this study, covering two groins and their adacent estuarine areas. By use of rinsing fix-bed model as well as localized mobile-bed model, the experiment is undertaken under bi-directional steady flow. According to the experimental results, waterway dredging leads to the increase in steram velocity, the increase being larger during the ebb than during the flood. Construction of the upstream groin has some influence on the flow patterns near the downstream groin. Localized scour in front of the groin-heads is controlled mainly by ebb flow. In the case of a riverbed composed entirely of silt, the depths of localized scour in front of the two groin- heads are 27 m and 29 m, respectively. In reality, the underneath sediment of the prototype riverbed is clay whose threshold velocity is much higher than the stream velocity in the Yangtze Estuary; therefore, the depths of localized scour will not be much larger than the thickness of the silt layer, i. e. 7.4 m and 4.7 m, respectively. The designed aprons covering the riverbed in fron of the groin-heads are very effective in scour control. Aprons of slightly smaller size can also fulfill the task of protection, but the area of localized scour increases significantly.展开更多
Recent studies have shown that the size of microvoids has a significant effect on the void growth rate.The purpose of this paper is to explore whether the void size effect can influence the plastic flow localization i...Recent studies have shown that the size of microvoids has a significant effect on the void growth rate.The purpose of this paper is to explore whether the void size effect can influence the plastic flow localization in ductile materials.We have used the extended Gurson's dilatational plasticity theory,which accounts for the void size effect,to study the plastic flow localization in porous solids with long cylindrical voids.The localization model of Rice is adopted,in which the material inside the band may display a different response from that outside the band at the incipient plastic flow localization.The present study shows that it has little effect on the shear band angle.展开更多
Oxygen reduction reaction(ORR)has been disclosed in recent studies as a significant secondary cathodic process during magnesium corrosion.This work elaborates on the contribution of ORR to the total corrosion process ...Oxygen reduction reaction(ORR)has been disclosed in recent studies as a significant secondary cathodic process during magnesium corrosion.This work elaborates on the contribution of ORR to the total corrosion process of pure Mg at different impurity levels in NaCl electrolyte with the assistance of local techniques.A finite element based numerical model taking into account the contribution of ORR during the corrosion of the Mg test materials has been designed in this study considering the local oxygen concentration.Respective computational simulations were calibrated based on the experimental data and evaluated accordingly.Finally,the simultaneous monitoring of local concentration of H_(2) and O_(2),and the combined modeling study reveal the relation between ORR and hydrogen evolution reaction.展开更多
Most of the near-field source localization methods are developed with the approximated signal model,because the phases of the received near-field signal are highly non-linear.Nevertheless,the approximated signal model...Most of the near-field source localization methods are developed with the approximated signal model,because the phases of the received near-field signal are highly non-linear.Nevertheless,the approximated signal model based methods suffer from model mismatch and performance degradation while the exact signal model based estimation methods usually involve parameter searching or multiple decomposition procedures.In this paper,a search-free near-field source localization method is proposed with the exact signal model.Firstly,the approximative estimates of the direction of arrival(DOA)and range are obtained by using the approximated signal model based method through parameter separation and polynomial rooting operations.Then,the approximative estimates are corrected with the exact signal model according to the exact expressions of phase difference in near-field observations.The proposed method avoids spectral searching and parameter pairing and has enhanced estimation performance.Numerical simulations are provided to demonstrate the effectiveness of the proposed method.展开更多
The precision of atmospheric dry delay model is closely correlated with the accuracy of GPS water vapor in the process of GPS (Global Position System) remote sensing. Radiosonde data (from 1996 to 2001) at Qingyuan ar...The precision of atmospheric dry delay model is closely correlated with the accuracy of GPS water vapor in the process of GPS (Global Position System) remote sensing. Radiosonde data (from 1996 to 2001) at Qingyuan are used to calculate the exact values of the atmospheric dry delay. Base on these calculations and the surface meteorological parameters, the local year and month correction models of dry delay at the zenith angle of 0° are established by statistical methods. The analysis result shows that the local model works better and is slight more sensitive to altitude angle than universal models and that it is not necessary to build models for each month due to the slight difference between year model and month model. Furthermore, when the altitude angle is less than 75°, the difference between curve path and straight path increases rapidly with altitude angle’s decrease.展开更多
Wireless sensor network(WSN)positioning has a good effect on indoor positioning,so it has received extensive attention in the field of positioning.Non-line-of sight(NLOS)is a primary challenge in indoor complex enviro...Wireless sensor network(WSN)positioning has a good effect on indoor positioning,so it has received extensive attention in the field of positioning.Non-line-of sight(NLOS)is a primary challenge in indoor complex environment.In this paper,a robust localization algorithm based on Gaussian mixture model and fitting polynomial is proposed to solve the problem of NLOS error.Firstly,fitting polynomials are used to predict the measured values.The residuals of predicted and measured values are clustered by Gaussian mixture model(GMM).The LOS probability and NLOS probability are calculated according to the clustering centers.The measured values are filtered by Kalman filter(KF),variable parameter unscented Kalman filter(VPUKF)and variable parameter particle filter(VPPF)in turn.The distance value processed by KF and VPUKF and the distance value processed by KF,VPUKF and VPPF are combined according to probability.Finally,the maximum likelihood method is used to calculate the position coordinate estimation.Through simulation comparison,the proposed algorithm has better positioning accuracy than several comparison algorithms in this paper.And it shows strong robustness in strong NLOS environment.展开更多
文摘In this paper, we study the flocking behavior of a thermodynamic Cucker–Smale model with local velocity interactions. Using the spectral gap of a connected stochastic matrix, together with an elaborate estimate on perturbations of a linearized system, we provide a sufficient framework in terms of initial data and model parameters to guarantee flocking. Moreover, it is shown that the system achieves a consensus at an exponential rate.
基金sponsored by Guangdong Basic and Applied Basic Research Foundation under Grant No.2021A1515110680Guangzhou Basic and Applied Basic Research under Grant No.202102020340.
文摘In this paper,we consider the Chan–Vese(C-V)model for image segmentation and obtain its numerical solution accurately and efficiently.For this purpose,we present a local radial basis function method based on a Gaussian kernel(GA-LRBF)for spatial discretization.Compared to the standard radial basis functionmethod,this approach consumes less CPU time and maintains good stability because it uses only a small subset of points in the whole computational domain.Additionally,since the Gaussian function has the property of dimensional separation,the GA-LRBF method is suitable for dealing with isotropic images.Finally,a numerical scheme that couples GA-LRBF with the fourth-order Runge–Kutta method is applied to the C-V model,and a comparison of some numerical results demonstrates that this scheme achieves much more reliable image segmentation.
文摘Spatio-temporal variability and dynamics in Sahelian agro-pastoral zones make each local situation a special case. These specificities must be considered to guide the dissemination of agricultural options with a view to sustainable development. The territorial scale of municipalities is not sufficient for this necessary contextualization;the scale of the “village terroir” seems to be a better option. This is the hypothesis we put forward in the framework of the Global Collaboration for Resilient Food Systems program (CRFS), i.e. local context is spatially defined by village terroir. The study is based on data collected through participatory mapping and surveys in “village terroirs” in three regions of Niger (Maradi, Dosso and Tillabéri). Then the links between farm managers and their cultivated land, as well as the spatio-temporal dynamics of local context are analyzed. This study provides evidence of the existence and functional usefulness of the village terroir for farmers, their land management and their activities. It demonstrates the usefulness of contextualizing agricultural options at this scale. Their analysis elucidates the links between “terroirs village” and the specific functioning of the agrosocio-ecosystems acting on each of them, thus laying the systemic and geographical foundations for a model of the spatio- temporal dynamics of “village terroirs”. This initial work has opened up new perspectives in modeling and sustainable development.
文摘In this paper,we prove the local existence and uniqueness of solutions to the evolutionary model for magnetoviscoelasticity in R^(2),R^(3).This model consists of an incompressible Navier-Stokes,a regularized system for the evolution of the deformation gradient and the Landau-Lifshitz-Gilbert system for the dynamics of the mag-netization.Our approach depends on approximating the system with a sequence of perturbed systems.
文摘In this paper,we explore bound preserving and high-order accurate local discontinuous Galerkin(LDG)schemes to solve a class of chemotaxis models,including the classical Keller-Segel(KS)model and two other density-dependent problems.We use the convex splitting method,the variant energy quadratization method,and the scalar auxiliary variable method coupled with the LDG method to construct first-order temporal accurate schemes based on the gradient flow structure of the models.These semi-implicit schemes are decoupled,energy stable,and can be extended to high accuracy schemes using the semi-implicit spectral deferred correction method.Many bound preserving DG discretizations are only worked on explicit time integration methods and are difficult to get high-order accuracy.To overcome these difficulties,we use the Lagrange multipliers to enforce the implicit or semi-implicit LDG schemes to satisfy the bound constraints at each time step.This bound preserving limiter results in the Karush-Kuhn-Tucker condition,which can be solved by an efficient active set semi-smooth Newton method.Various numerical experiments illustrate the high-order accuracy and the effect of bound preserving.
文摘Active shape models (ASM), consisting of a shape model and a local gray-level appearance model, can be used to locate the objects in images. In original ASM scheme, the model of object′s gray-level variations is based on the assumption of one-dimensional sampling and searching method. In this work a new way to model the gray-level appearance of the objects is explored, using a two-dimensional sampling and searching technique in a rectangular area around each landmark of object shape. The ASM based on this improvement is compared with the original ASM on an identical medical image set for task of spine localization. Experiments demonstrate that the method produces significantly fast, effective, accurate results for spine localization in medical images.
基金Project(2004F052) supported by the Education Department of Liaoning Province,China
文摘By using the widely used JOHNSON-COOK model and the gradient-dependent plasticity to consider microstructural effect beyond the occurrence of shear strain localization,the distributions of local plastic shear strain and deformation in adiabatic shear band(ASB)were analyzed.The peak local plastic shear strain is proportional to the average plastic shear strain,while it is inversely proportional to the critical plastic shear strain corresponding to the peak flow shear stress.The relative plastic shear deformation between the top and base of ASB depends on the thickness of ASB and the average plastic shear strain.A parametric study was carried out to study the influence of constitutive parameters on shear strain localization.Higher values of static shear strength and work to heat conversion factor lead to lower critical plastic shear strain so that the shear localization is more apparent at the same average plastic shear strain.Higher values of strain-hardening exponent,strain rate sensitive coefficient,melting point,thermal capacity and mass density result in higher critical plastic shear strain,leading to less apparent shear localization at the same average plastic shear strain.The strain rate sensitive coefficient has a minor influence on the critical plastic shear strain,the distributions of local plastic shear strain and deformation in ASB.The effect of strain-hardening modulus on the critical plastic shear strain is not monotonous.When the maximum critical plastic shear strain is reached,the least apparent shear localization occurs.
基金supported by the Program for Changjiang Scholars and Innovative Research Team in University of China under contract No,IRT0420the National Natural Science Foundation of China under contract No.50409015.
文摘The mechanism of local scour around submarine pipelines is studied numerically based on a renormalized group (RNG) turbulence model. To validate the numerical model, the equilibrium profiles of local scour for two cases are simulated and compared with the experimental data. It shows that the RNG turbulence model can give an appropriate prediction for the configuration of equilibrium scour hole, and it is applicable to this situation. The local scour mechanism around submarine pipelines including the flow structure, shear stress distribution and pressure field is then analyzed and compared with experiments. For further comparison and validation, especially for the flow structure, a numerical calculation employing the large eddy simulation (LES) is also conducted. The numerical results of RNG demonstrate that the critical factor governing the equilibrium profile is the seabed shear stress distribution in the case of bed load sediment transport, and the two-equation RNG turbulence model coupled with the law of wall is capable of giving a satisfying estimation for the bed shear stress. Moreover, the piping phenomena due to the great difference of pressure between the upstream and downstream parts of pipelines and the vortex structure around submarine pipelines are also simulated successfully, which are believed to be the important factor that lead to the onset of local scour.
基金supported by grants from the National Natural Science Foundation of China (grant number 81625005 to Z.F.)High-level Talents of the Beijing Health System (grant number 2014-3-080 to F.Z.)the program for Beijing Science and Technology of Chinese Medicine (grant number JJ2013-11 to F.Z.)
文摘Periodontitis is an inflammatory autoimmune disease. Treatment should alleviate inflammation, regulate the immune reaction and promote periodontal tissue regeneration. Icariin is the main active ingredient of Epimedii Folium, and it is a promising compound for the enhancement of mesenchymal stem cell function, promotion of bone formation, inhibition of bone resorption, alleviation of inflammation and regulation of immunity. The study investigated the effect of icariin on periodontal tissue regeneration in a minipig model of periodontitis. The minipig model of periodontitis was established. Icariin was injected locally. The periodontal clinical assessment index, a computed tomography(CT) scan, histopathology and enzyme-linked immune sorbent assay(ELISA)were used to evaluate the effects of icariin. Quantitative analysis results 12 weeks post-injection demonstrated that probing depth,gingival recession, attachment loss and alveolar bone regeneration values were(3.72 ± 1.18) mm vs.(6.56 ± 1.47) mm,(1.67 ± 0.59)mm vs.(2.38 ± 0.61) mm,(5.56 ± 1.29) mm vs.(8.61 ± 1.72) mm, and(25.65 ± 5.13) mm3 vs.(9.48 ± 1.78) mm3 in the icariin group and0.9% NaCl group, respectively. The clinical assessment, CT scan, and histopathology results demonstrated significant enhancement of periodontal tissue regeneration in the icariin group compared to the 0.9% NaCl group. The ELISA results suggested that the concentration of interleukin-1 beta(IL-1β) in the icariin group was downregulated compared to the 0.9% NaCl group, which indicates that local injection of icariin relieved local inflammation in a minipig model of periodontitis. Local injection of icariin promoted periodontal tissue regeneration and exerted anti-inflammatory and immunomodulatory function. These results support the application of icariin for the clinical treatment of periodontitis.
基金Project([2005]205)supported by the Science and Technology Planning Project of Water Resources Department of Guangdong Province,ChinaProject(2012-7)supported by Guangdong Bureau of Highway Administration,ChinaProject(2012210020203)supported by the Fundamental Research Funds for the Central Universities,China
文摘Employing an ideal elasto-plastic model,the typically used strength reduction method reduced the strength of all soil elements of a slope.Therefore,this method was called the global strength reduction method(GSRM).However,the deformation field obtained by GSRM could not reflect the real deformation of a slope when the slope became unstable.For most slopes,failure occurs once the strength of some regional soil is sufficiently weakened; thus,the local strength reduction method(LSRM)was proposed to analyze slope stability.In contrast with GSRM,LSRM only reduces the strength of local soil,while the strength of other soil remains unchanged.Therefore,deformation by LSRM is more reasonable than that by GSRM.In addition,the accuracy of the slope's deformation depends on the constitutive model to a large degree,and the variable-modulus elasto-plastic model was thus adopted.This constitutive model was an improvement of the Duncan–Chang model,which modified soil's deformation modulus according to stress level,and it thus better reflected the plastic feature of soil.Most importantly,the parameters of the variable-modulus elasto-plastic model could be determined through in-situ tests,and parameters determination by plate loading test and pressuremeter test were introduced.Therefore,it is easy to put this model into practice.Finally,LSRM and the variable-modulus elasto-plastic model were used to analyze Egongdai ancient landslide.Safety factor,deformation field,and optimal reinforcement measures for Egongdai ancient landslide were obtained based on the proposed method.
文摘In this article, authors introduce a method to assess local influence of obser- vations on the parameter estimates and prediction in multivariate regression model. The diagnostics under the perturbations of error variance, response variables and explanatory variables are derived, and the results are compared with those of case- deletion. Two examples are analyzed for illustration.
文摘In order to examine the effectiveness of engineering protection against localized scour in front of the south groin-group of the Yangtze Estuary Waterway Improvement Project, Phase I , an undistort-ed physical model on a geometric scale of 1:250 is built in this study, covering two groins and their adacent estuarine areas. By use of rinsing fix-bed model as well as localized mobile-bed model, the experiment is undertaken under bi-directional steady flow. According to the experimental results, waterway dredging leads to the increase in steram velocity, the increase being larger during the ebb than during the flood. Construction of the upstream groin has some influence on the flow patterns near the downstream groin. Localized scour in front of the groin-heads is controlled mainly by ebb flow. In the case of a riverbed composed entirely of silt, the depths of localized scour in front of the two groin- heads are 27 m and 29 m, respectively. In reality, the underneath sediment of the prototype riverbed is clay whose threshold velocity is much higher than the stream velocity in the Yangtze Estuary; therefore, the depths of localized scour will not be much larger than the thickness of the silt layer, i. e. 7.4 m and 4.7 m, respectively. The designed aprons covering the riverbed in fron of the groin-heads are very effective in scour control. Aprons of slightly smaller size can also fulfill the task of protection, but the area of localized scour increases significantly.
基金The project supported by the National Natural Science Foundation of China (10121202) and Ministry of Education,China (20020003023 and Key Grant Project 0306)
文摘Recent studies have shown that the size of microvoids has a significant effect on the void growth rate.The purpose of this paper is to explore whether the void size effect can influence the plastic flow localization in ductile materials.We have used the extended Gurson's dilatational plasticity theory,which accounts for the void size effect,to study the plastic flow localization in porous solids with long cylindrical voids.The localization model of Rice is adopted,in which the material inside the band may display a different response from that outside the band at the incipient plastic flow localization.The present study shows that it has little effect on the shear band angle.
基金the China Scholarship Council for the award of fellowship and funding(No.201806310128,201908510177)。
文摘Oxygen reduction reaction(ORR)has been disclosed in recent studies as a significant secondary cathodic process during magnesium corrosion.This work elaborates on the contribution of ORR to the total corrosion process of pure Mg at different impurity levels in NaCl electrolyte with the assistance of local techniques.A finite element based numerical model taking into account the contribution of ORR during the corrosion of the Mg test materials has been designed in this study considering the local oxygen concentration.Respective computational simulations were calibrated based on the experimental data and evaluated accordingly.Finally,the simultaneous monitoring of local concentration of H_(2) and O_(2),and the combined modeling study reveal the relation between ORR and hydrogen evolution reaction.
基金supported by the Key Laboratory of Dynamic Cognitive System of Electromagnetic Spectrum Space(KF20202109)the National Natural Science Foundation of China(82004259)the Young Talent Training Project of Guangzhou University of Chinese Medicine(QNYC20190110).
文摘Most of the near-field source localization methods are developed with the approximated signal model,because the phases of the received near-field signal are highly non-linear.Nevertheless,the approximated signal model based methods suffer from model mismatch and performance degradation while the exact signal model based estimation methods usually involve parameter searching or multiple decomposition procedures.In this paper,a search-free near-field source localization method is proposed with the exact signal model.Firstly,the approximative estimates of the direction of arrival(DOA)and range are obtained by using the approximated signal model based method through parameter separation and polynomial rooting operations.Then,the approximative estimates are corrected with the exact signal model according to the exact expressions of phase difference in near-field observations.The proposed method avoids spectral searching and parameter pairing and has enhanced estimation performance.Numerical simulations are provided to demonstrate the effectiveness of the proposed method.
基金Sino-Italian Cooperation Project "An Integrated System for the Planning, Monitoring and Real-time Forecasting of Floods Risks"
文摘The precision of atmospheric dry delay model is closely correlated with the accuracy of GPS water vapor in the process of GPS (Global Position System) remote sensing. Radiosonde data (from 1996 to 2001) at Qingyuan are used to calculate the exact values of the atmospheric dry delay. Base on these calculations and the surface meteorological parameters, the local year and month correction models of dry delay at the zenith angle of 0° are established by statistical methods. The analysis result shows that the local model works better and is slight more sensitive to altitude angle than universal models and that it is not necessary to build models for each month due to the slight difference between year model and month model. Furthermore, when the altitude angle is less than 75°, the difference between curve path and straight path increases rapidly with altitude angle’s decrease.
基金supported by the National Natural Science Foundation of China under Grant No.62273083 and No.61973069Natural Science Foundation of Hebei Province under Grant No.F2020501012。
文摘Wireless sensor network(WSN)positioning has a good effect on indoor positioning,so it has received extensive attention in the field of positioning.Non-line-of sight(NLOS)is a primary challenge in indoor complex environment.In this paper,a robust localization algorithm based on Gaussian mixture model and fitting polynomial is proposed to solve the problem of NLOS error.Firstly,fitting polynomials are used to predict the measured values.The residuals of predicted and measured values are clustered by Gaussian mixture model(GMM).The LOS probability and NLOS probability are calculated according to the clustering centers.The measured values are filtered by Kalman filter(KF),variable parameter unscented Kalman filter(VPUKF)and variable parameter particle filter(VPPF)in turn.The distance value processed by KF and VPUKF and the distance value processed by KF,VPUKF and VPPF are combined according to probability.Finally,the maximum likelihood method is used to calculate the position coordinate estimation.Through simulation comparison,the proposed algorithm has better positioning accuracy than several comparison algorithms in this paper.And it shows strong robustness in strong NLOS environment.