Principles for Designing New Types of Housing for a Strong and Resilient Local Economy in the Republic of Congo

The Congolese population is organised into households, which are thus headed by a chief who ensures the social well-being, development and integration into working life of the individuals in his charge. This study examines the functional principles of new housing design as an instrument for transforming the (current) failing economy into a strong and resilient one. Accordingly, a literature review of the practice of designing and building housing in human settlements in the Congo revealed the state of the art on this subject. An analysis of the existing housing stock from a demographic, social and economic point of view made it possible to identify the most common household sizes and numbers, as well as the lifestyle processes that determine the need for developed space. To this end, the experimental method was used to propose configuration plans for various new types of dwelling. To this end, the study highlighted the link between people’s standard of living and the effectiveness of their involvement in the local economy. To achieve the aims of the National Development Plan (NDP), particular attention must be paid to solving the housing problem. The existing housing stock actively contributes to the problems associated with unemployment and insecurity. Functional principles for the design of new types of housing have been developed. Four model types are proposed in line with the demographic structure of the population, their socio-economic characteristics and their lifestyle.

Developing high-efficiency base editors by combining optimized synergistic core components with new types of nuclear localization signal peptide

The clustered regularly interspaced short palindromic repeats(CRISPR)–CRISPR-associated protein(Cas) system has been widely used for genome editing. In this system, the cytosine base editor(CBE) and adenine base editor(ABE) allow generating precise and irreversible base mutations in a programmable manner and have been used in many different types of cells and organisms. However, their applications are limited by low editing efficiency at certain genomic target sites or at specific target cytosine(C) or adenine(A) residues. Using a strategy of combining optimized synergistic core components, we developed a new multiplex super-assembled ABE(sABE) in rice that showed higher base-editing efficiency than previously developed ABEs. We also designed a new type of nuclear localization signal(NLS) comprising a FLAG epitope tag with four copies of a codon-optimized NLS(F4NLS^(r2)) to generate another ABE named F4NLS-sABE. This new NLS increased editing efficiency or edited additional A at several target sites. A new multiplex super-assembled CBE(sCBE) and F4NLS^(r2) involved F4NLS-sCBE were also created using the same strategy. F4NLS-sCBE was proven to be much more efficient than sCBE in rice. These optimized base editors will serve as powerful genome-editing tools for basic research or molecular breeding in rice and will provide a reference for the development of superior editing tools for other plants or animals.

ON RIESZ TYPE KERNELS OVER LOCAL FIELDS

Based on a representation lemma. Riesz type kernels on the local field K and on the integer ring O in K are coitstructed. Furthermore, we discuss approximation theorems for the Lipschitz class Lip(L ;α) ana the Lp boundedness of such operators motivated by the open problem: Does σηfa,s→f for f ∈L1(O) (see M. H. Taible-son [6] and [5])?

On Local Existence and Blow-Up of Solutions for Nonlinear Wave Equations of Higher-Order Kirchhoff Type with Strong Dissipation

In this paper, we study on the initial-boundary value problem for nonlinear wave equations of higher-order Kirchhoff type with Strong Dissipation: . At first, we prove the existence and uniqueness of the local solution by the Banach contraction mapping principle. Then, by “Concavity” method we establish three blow-up results for certain solutions in the case 1): , in the case 2): and in the case 3): . At last, we consider that the estimation of the upper bounds of the blow-up time is given for deferent initial energy.

ON TRANSMISSION PROBLEM FOR KIRCHHOFF TYPE WAVE EQUATION WITH A LOCALIZED NONLINEAR DISSIPATION IN BOUNDED DOMAIN

In this article, we consider the global existence and decay rates of solutions for the transmission problem of Kirchhoff type wave equations consisting of two physi- cally different types of materials, one component is a Kirchhoff type wave equation with nonlinear time dependent localized dissipation which is effective only on a neighborhood of certain part of the boundary, while the other is a Kirchhoff type wave equation with nonlinear memory.

Three-Level Λ-Type Atomic System Localized by the Parameters of the Two Orthogonal Standing-Wave Fields

Localization of the three-level Λ-type atomic system interacting with two orthogonal standing-wave fields is proposed. Two equal and tunable peaks in the 2D plane are obtained by the detunings corresponding to the two orthogonal standing-wave fields when the decreasing intensities of spontaneously generated coherence (SGC) arise in the three-level Λ-type atomic system, while one circular ring with shrinking radii in the 2D plane is obtained by the adjusted phases and wave vectors of the standing-wave fields when the increasing intensities of SGC occur in the three-level Λ-type atomic system. 2D atom localization with the single ring with shrinking radii realized by the multiple parametric manipulations demonstrated the flexibility for our scheme.

Sufficiency and Wolfe Type Duality for Nonsmooth Multiobjective Programming Problems

In this paper, a class of nonsmooth multiobjective programming problems is considered. We introduce the new concept of invex of order??type II for nondifferentiable locally Lipschitz functions using the tools of Clarke subdifferential. The new functions are used to derive the sufficient optimality condition for a class of nonsmooth multiobjective programming problems. Utilizing the sufficient optimality conditions, weak and strong duality theorems are established for Wolfe type duality model.

Construction Theory of Function on Local Fields

We establish the construction theory of function based upon a local field Kp as underlying space. By virture of the concept of pseudo-differential operator, we introduce ＂fractal calculus＂ （or, p-type calculus, or, Gibbs-Butzer calculus）. Then, show the Jackson direct approximation theorems, Bermstein inverse approximation theorems and the equivalent approximation theorems for compact group D（C Kp） and locally compact group Kp^＋-（= Kp）, so that the foundation of construction theory of function on local fields is established. Moreover, the Jackson type, Bernstein type, and equivalent approximation theorems on the HOlder-type space C^σ（Kp）, σ 〉0, are proved; then the equivalent approximation theorem on Sobolev-type space Wr（Kp）, σ≥0, 1≤r 〈∞, is shown.

新工科背景下现代产业学院的建构与实践路径研究

为培养适应经济社会发展需求的食品、制药专业本科生,许昌学院积极建设食品医药与健康产业学院(校级)。通过分析产业学院理论研究现状及实地走访调研,发现目前产业学院仍存在形式化、表面化等问题,产教融合层次低、形式松散,融不进去、深不下去的现象突出,提出解决目前困境的三个关键措施。通过组建科学合理的产业学院决策机构、实行股份制、建立董事会、加强内部管理机制增强综合管理效能、构建教学质量保障体系等举措,推动现代产业学院建设持续健康发展,建设深度融合、差异发展、资源整合的现代产业学院。通过不断探索,找到了一条适合地方应用型院校现代产业学院建设的路径,建立了一套适合地方应用型普通本科院校食品、制药专业学生培养的教学模式,为“许昌模式”注入了新的内涵。

以“五实”教育为主线的多样化应用型人才培养模式研究

面对经济结构调整和产业结构升级,新产业、新技术、新业态不断出现,使得企业对应用型人才有大量的需求,地方高校为适应现代社会发展的需要,必须改革和创新原来单一化的人才培养模式。以沈阳城市建设学院为案例,探讨地方高校应用型人才培养背景,提出多元化应用型人才培养模式,以“五实”教育为主线,对模式核心内容进行详细阐述,该校从调整人才培养方案入手,在教学设计、课程设置、实习环节、专业实习和毕业设计等方面进行系列改革。以“五实”教育为主线的多样化应用型人才培养模式的实践过程,为地方本科高校应用型人才培养提供借鉴。

地方高校图书馆开展社会服务的有效途径

新形势下,高校图书馆深化服务内涵、拓展服务职能、积极开展社会服务,既是地方社会经济文化发展的需要,也是高校转型发展和图书馆自身发展的需要。因此,地方高校图书馆要立足地方、面向社会,以加强资源共享和提高资源利用率为导向,不断深化社会服务内涵、创新社会服务模式、提升社会服务水平。以整合现有资源为基础,地方高校图书馆应加强与当地中小学、社区、乡镇及其他职能部门合作,从最基本的文献资料服务入手,逐步拓展、延伸和提高,积极参与地方基础教育发展,推动社区文化和地方特色文化建设,为地方文化建设和社会经济发展做出应有贡献。

Body Response to Local Muscular Performance of Individuals Engaged in Various Professional Occupations

We have compared 142 adult men and women of various ages, grouped by professional occupation, all the occupations involving local muscular performance. We studied heart reactions and central nervous system reactions to local muscular performance done until fatigue set in. The results suggested that adaptive body changes had a number of shared signs, namely, tachycardia, hypertension, and increased statistical figures of the heart rhythm, which were indicative of tension in central regulatory mechanisms of the heart.

新文科建设背景下地方师范院校应用型设计学专业课程混合式教学研究

在新文科建设时代背景下,高等教育对人才培养的要求逐渐转向多元化与综合性的方向。地方师范院校作为培养基础教育师资及应用型人才的重要阵地,其内部设计学专业课程在改革创新过程中就显得尤为重要,而混合式教学作为一种融入了线上教学与线下教学优势的新型教学模式,将会为设计学专业课程的深化改革提供新的思路与方向。基于此,本文就新文科建设背景下地方师范院校应用型设计学专业课程混合式教学研究展开相关探讨。

地方本科院校硕士生综合表现与生源关系分析——基于A高校管理学院的实证研究

从硕士研究生的性别、本科学校层次及升学方式三个方面,系统分析地方本科院校A高校管理学院硕士研究生的综合表现与生源关系。研究发现地方本科院校硕士生中女学生整体综合表现优于男生,但男生拔尖比例更高。“双一流”生源的学生获一等和二等奖学金的综合比例高于非“双一流”院校,但这种差距在逐渐缩小。推免生生源占比偏低,并且在研究生期间整体表现良而不优,需要引起关注。生源与研究生综合表现之间关系复杂,没有必然联系,在重视提高生源质量的同时更重要的是研究生期间学校的培养和学生的努力。

135/8-10M卡爪式水下液压连接器国产化研制

在分析国内外技术现状的基础上,详细说明宝鸡石油机械有限责任公司研制的135/8-10M卡爪式水下液压连接器的总体结构、技术参数和有限元分析结果,介绍样机制造和试验情况,并对卡爪式水下液压连接器的结构特点进行总结。该卡爪式水下液压连接器具有液压锁紧和多重解锁、位置指示、型面自锁、垫环固位和更换等功能,产品通过挪威船级社(DNV)和中国船级社(CCS)双认证,并取得API 17D证书,开展与用户设备的现场联调测试,有力推动水下油气装备关键部件的国产化。

DIMENSION RESULTS FORORNSTEIN-UHLENBECK TYPE MARKOVPROCESS

Let {X-t, t greater than or equal to 0} be an Ornstein-Uhlenbeck type Markov process with Levy process A(t), the authors consider the fractal properties of its ranges, give the upper and lower bounds of the Hausdorff dimensions of the ranges and the estimate of the dimensions of the level sets for the process. The existence of local times and occupation times of X-t are considered in some special situations.

双高背景下高职院校科研功能的认知误区与消解之策

引领新时代职业教育实现高质量发展是“双高计划”落地的总体目标,这需要高职院校重视科研创新,强化内涵建设。然而,在高职院校中还存在着科研无关论、科研无力论、科研冲突论、科研无路论和科研无用论等科研功能认识偏误。高职院校需明晰科研应服务高职院校高水平建设,促进高职教师专业发展,赋能职业教育人才培养,推动职业技术研发与应用的应然价值,从以下方面消解高职院校科研功能的认知误区。一是明确科研错位发展,打破“科研无关论”困局;二是营造良好科研服务氛围,回应“科研无力论”争议;三是发挥科研反哺教学和育人作用,破解“科研冲突论”难题;四是打造优质科研合作平台,破解“科研无路论”困境;五是构建科学评价体系,扭转“科研无用论”风气。

Explicit Multi-symplectic Method for a High Order Wave Equation of KdV Type

In this paper, we consider multi-symplectic Fourier pseudospectral method for a high order integrable equation of KdV type, which describes many important physical phenomena. The multi-symplectic structure are constructed for the equation, and the conservation laws of the continuous equation are presented. The multisymplectic discretization of each formulation is exemplified by the multi-symplectic Fourier pseudospectral scheme. The numerical experiments are given, and the results verify the efficiency of the Fourier pseudospectral method.

大理苍山模式标本植物富集的原因探析

大理苍山是中国模式标本植物最为集中地区之一。为厘清苍山模式标本植物富集的原因,基于现有文献和物种信息数字化平台(如CVH、iplant、sp2000),对现有模式标本产自苍山或苍山附近的种子植物名录进行整理,获得目前被广泛接受的模式标本植物名录,并分析其特有性;对苍山植物标本采集的时空动态进行分析,探究苍山模式标本植物众多的历史原因。结果显示:(1)目前共记录苍山产模式标本种子植物297种,其中苍山特有种22种。(2)苍山植物标本采集的历史可追溯至1883年。1900-2020年的121年间,有118个年度都在大理发生了植物标本采集事件(频率达97.5%);1905-2017年的113年间,有80个年度都在苍山发生了植物标本采集事件(频率70.8%)。在大理采集量出现峰值的16个年度中,8个年度也有在苍山采集的记录,同步率50%。结果表明:(1)苍山的地理位置独特,位于多个植物区系的交汇地带,自然条件孕育了丰富的生物多样性和特有种群。同时,其紧邻大理古城的地理优势,使其成为滇西、滇西北地区植物探索的重要节点。自1883年以来,国内外植物学家频繁造访苍山,促进了新物种的发现与描述,进而增加了苍山产模式标本植物的种类多样性。(2)植物模式标本产地种群携带有物种形态学、生态学和遗传学等有用的研究信息,对其保护宜以就地保护为好。建议加强对苍山产模式标本植物原产地种群的就地保护措施,以保护这一珍贵的生物多样性资源。

新辅助化疗联合阴式广泛子宫切除术治疗Ⅱa期局部肿块型宫颈癌的临床疗效

目的探讨新辅助化疗联合阴式广泛子宫切除术对Ⅱa期局部肿块型宫颈癌的治疗效果。方法根据治疗方式的不同将97例Ⅱa期局部肿块型宫颈癌患者分为观察组(n=47)和对照组(n=50),对照组患者接受阴式广泛子宫切除术治疗,观察组患者接受新辅助化疗联合阴式广泛子宫切除术治疗。评估观察组患者的临床疗效,比较两组患者肿瘤标志物[癌胚抗原(CEA)、鳞状细胞癌抗原(SCC-Ag)、糖类抗原15-3(CA15-3)]水平、T淋巴细胞亚群(CD3^(+)、CD4^(+)、CD8^(+)、CD4^(+)/CD8^(+))水平、生活质量[世界卫生组织生活质量测定量表简表(WHOQOL�BREF)]及不良反应发生情况。结果观察组患者的总有效率为78.72%。手术后,两组患者CEA、SCC-Ag、CA15-3水平均低于本组治疗前,观察组患者CEA、SCC-Ag、CA15-3水平均低于对照组,差异均有统计学意义(P﹤0.05)。手术后,观察组患者CD3^(+)、CD4^(+)水平和CD4^(+)/CD8^(+)均高于对照组,CD8^(+)水平低于对照组,差异均有统计学意义(P﹤0.05)。手术后,两组患者生理、心理、环境、社会关系评分均高于本组治疗前,观察组患者生理、心理、环境、社会关系评分均高于对照组,差异均有统计学意义(P﹤0.05)。两组患者恶心呕吐、脱发、骨髓抑制、肝肾功能减退发生率比较,差异均无统计学意义(P﹥0.05)。结论新辅助化疗联合阴式广泛子宫切除术对Ⅱa期局部肿块型宫颈癌的治疗效果较好,可降低肿瘤标志物水平,改善免疫功能,提高生活质量,且不良反应发生率较低。