Enhancement of spatial resolution of ghost imaging via localizing and thresholding

In ghost imaging, an illumination light is split into test and reference beams which pass through two different optical systems respectively and an image is constructed with the second-order correlation between the two light beams. Since both light beams are diffracted when passing through the optical systems, the spatial resolution of ghost imaging is in general lower than that of a corresponding conventional imaging system. When Gaussian-shaped light spots are used to illuminate an object, randomly scanning across the object plane, in the ghost imaging scheme, we show th√at by localizing central positions of the spots of the reference light beam, the resolution can be increased by a factor of 2^(1/2) same as that of the corresponding conventional imaging system. We also find that the resolution can be further enhanced by setting an appropriate threshold to the bucket measurement of ghost imaging.

Arterial stimulation with simultaneous venous sampling for localizing insulinomas

Purpose: The present study aimed to assess the accuracies of arterial stimulation with simultaneous venous sampling(ASVS) in preoperative localization of insulinomas. Materials and Methods: A cohort consisting of 6 males and 14 females(median age, 48.5y; range, 28–62y) with pathologically proven insulinomas were included in this study. Selective angiographies were performed with the superior mesenteric artery(SMA), gastroduodenal artery(GDA), proximal splenic artery, and midsplenic artery in all individuals. Then ASVS procedures were followed after angiographies for these arteries. Clinical characteristics of the patient and the tumor number, location, and size were recorded. The accuracy of preoperative localization of insulinomas was tested. Results: A total of 22 tumors were identified by histopathological diagnosis. The mean size of the tumor was 1.40±0.60 cm. Five tumors were in the head/neck region and 17 in the body/tail region. ASVS accurately localized 17/20(85%) cases with only biochemical data and 19/20(95%) cases with biochemical data and angiography images. Variant pancreatic arterial anatomy was revealed in 2 false cases with inferior pancreatic artery replaced by the superior mesenteric artery. Conclusion: ASVS was highly accurate in localizing insulinomas and should be performed in most of the patients with suspected insulinomas before the operation.

A wireless magnetic sensor for localizing in-vivo medical micro-devices

In order to measure the position and orientation of in-vivo medical micro-devices without the line-of- sight constraints, a wireless magnetic sensor is developed for an electromagnetic localization method. In the electromagnetic localization system, the wireless magnetic sensor is embedded in the micro-devices to measure alternating magnetic signals. The wireless magnetic sensor is composed of an induction coil, a signal processor, a radio frequency （R.F） transmitter, a power manager and batteries. Based on the principle of electromagnetic induction, the induction coil converts the alternating magnetic signals into electrical signals. Via the RF transmitter, the useful data am wirelessly sent outside the body. According to the relation between the magnetic signals and the location, the position and orientation of the micro-devices can be calculated. The experiments demonstrate the feasibility of localizing in-vivo medical micro-devices with the wireless magnetic sensor. The novel localization system is accurate and robust.

A TDOA-Based Ultrasonic Absolute Localizing System of a Rail Robot in Greenhouse

In this paper,we present a method for localization of a rail autonomous pesticide spraying and sampling robot working in greenhouse using an absolute localization system.Design and implementation of the localization system comes from the usage of beacon systems each of which is composed of an RF single receiver and an ultrasonic transmitter.The RF single receiver gets the synchronization signal from the mobile robot,and the ultrasonic transmitter sends ultrasonic signal,thus the distance from the beacon to the ultrasonic receiver can be measured.The position of a beacon in coordinate system of robot can be calculated according to distance information from the beacons to two ultrasonic receivers which are mounted on the robot.Based on the coordinate transformation,the position of a mobile robot can be calculated from the beacon＇s absolute position information in the global coordinate system.Experiments demonstrate the effectiveness of the proposed method in real world applications.

Localizing Jammer in an Indoor Environment by Estimating Signal Strength and Kalman Filter

Localizing a jammer in an indoor environment in wireless sensor networks becomes a significant research problem due to the ease of blocking the communication between legitimate nodes. An adversary may emit radio frequency to prevent the transmission between nodes. In this paper, we propose detecting the position of the jammer indoor by using the received signal strength and Kalman filter (KF) to reduce the noise due to the multipath signal caused by obstacles in the indoor environment. We compare our work to the Linear Prediction Algorithm (LP) and Centroid Localization Algorithm (CL). We observed that the Kalman filter has better results when estimating the distance compared to other algorithms.

Identifying and localizing of seismogenic electromagnetic anomalies from data observed by permanent MT stations

In this research, an arbitrarily oriented electric dipole at subsurface is used to simulate Seismogenic Electromagnetic(SEM) radiation emanating from a seismic zone during its gestation phase. Analytical synthesis of responses at the Lijiang magnetotelluric(MT) station has revealed that SEM radiation could induce identifiable anomalies in the electromagnetic(EM)spectrum, apparent resistivity and phase within specific frequency bands. Background variations were extracted from long-term observation data of Dali and Lijiang MT stations, enabling the identification of SEM anomalies related to the Yunlong and Yangbi earthquakes. Multiple parameters of dipole sources at subsurface were obtained by applying the Differential Ant Colony Optimization(DACO) algorithm to anomalous data of two stations with multi-frequencies and various response functions. The spatial distribution of these predicted dipoles is predominantly clustered in or around the seismogenic area, with their azimuthal orientation aligning towards the seismogenic fault in general. This study has demonstrated the potential of using subsurface electric dipole simulations for SEM radiation analysis, offering a feasible approach for the prediction and understanding of seismogenic zones.

Navigating the pathways:TAR-DNA-binding-protein-43 aggregation,axonal transport,and local synthesis in amyotrophic lateral sclerosis pathology

Neurons are highly polarized cells with axons reaching over a meter long in adult humans.To survive and maintain their proper function,neurons depend on specific mechanisms that regulate spatiotemporal signaling and metabolic events,which need to be carried out at the right place,time,and intensity.Such mechanisms include axonal transport,local synthesis,and liquid-liquid phase separations.Alterations and malfunctions in these processes are correlated to neurodegenerative diseases such as amyotrophic lateral sclerosis(ALS).

A functional tacrolimus-releasing nerve wrap for enhancing nerve regeneration following surgical nerve repair

Axonal regeneration following surgical nerve repair is slow and often incomplete,resulting in poor functional recovery which sometimes contributes to lifelong disability.Currently,there are no FDA-approved therapies available to promote nerve regeneration.Tacrolimus accelerates axonal regeneration,but systemic side effects presently outweigh its potential benefits for peripheral nerve surgery.The authors describe herein a biodegradable polyurethane-based drug delivery system for the sustained local release of tacrolimus at the nerve repair site,with suitable properties for scalable production and clinical application,aiming to promote nerve regeneration and functional recovery with minimal systemic drug exposure.Tacrolimus is encapsulated into co-axially electrospun polycarbonate-urethane nanofibers to generate an implantable nerve wrap that releases therapeutic doses of bioactive tacrolimus over 31 days.Size and drug loading are adjustable for applications in small and large caliber nerves,and the wrap degrades within 120 days into biocompatible byproducts.Tacrolimus released from the nerve wrap promotes axon elongation in vitro and accelerates nerve regeneration and functional recovery in preclinical nerve repair models while off-target systemic drug exposure is reduced by 80%compared with systemic delivery.Given its surgical suitability and preclinical efficacy and safety,this system may provide a readily translatable approach to support axonal regeneration and recovery in patients undergoing nerve surgery.

Cortico-striatal gamma oscillations are modulated by dopamine D3 receptors in dyskinetic rats

Long-term levodopa administration can lead to the development of levodopa-induced dyskinesia.Gamma oscillations are a widely recognized hallmark of abnormal neural electrical activity in levodopa-induced dyskinesia.Currently,studies have reported increased oscillation power in cases of levodopa-induced dyskinesia.However,little is known about how the other electrophysiological parameters of gamma oscillations are altered in levodopa-induced dyskinesia.Furthermore,the role of the dopamine D3 receptor,which is implicated in levodopa-induced dyskinesia,in movement disorder-related changes in neural oscillations is unclear.We found that the cortico-striatal functional connectivity of beta oscillations was enhanced in a model of Parkinson’s disease.Furthermore,levodopa application enhanced cortical gamma oscillations in cortico-striatal projections and cortical gamma aperiodic components,as well as bidirectional primary motor cortex(M1)↔dorsolateral striatum gamma flow.Administration of PD128907(a selective dopamine D3 receptor agonist)induced dyskinesia and excessive gamma oscillations with a bidirectional M1↔dorsolateral striatum flow.However,administration of PG01037(a selective dopamine D3 receptor antagonist)attenuated dyskinesia,suppressed gamma oscillations and cortical gamma aperiodic components,and decreased gamma causality in the M1→dorsolateral striatum direction.These findings suggest that the dopamine D3 receptor plays a role in dyskinesia-related oscillatory activity,and that it has potential as a therapeutic target for levodopa-induced dyskinesia.

Irreversible electroporation for metastatic pancreatic carcinoma with liver metastasis:What does the evidence say

Irreversible electroporation is a promising non-thermal ablation method that has been shown to increase overall survival in locally advanced pancreatic cancer in some studies.However,higher quality studies with proper controls and randomization are required to establish its superiority when added with neoadjuvant chemotherapy over the current management of choice,which is chemotherapy alone.Further studies are required before establishment of any survival benefit in metastatic pancreatic carcinoma,and such evidence is lacking at present.

Random lasing in an Anderson localizing optical fiber

A directional random laser mediated by transverse Anderson localization in a disordered glass optical fiber is reported.Previous demonstrations of random lasers have found limited applications because of their multi-directionality and chaotic fluctuations in the laser emission.The random laser presented in this paper operates in the Anderson localization regime.The disorder induced localized states form isolated local channels that make the output laser beam highly directional and stabilize its spectrum.The strong transverse disorder and longitudinal invariance result in isolated lasing modes with negligible interaction with their surroundings,traveling back and forth in a Fabry–Perot cavity formed by the air–fiber interfaces.It is shown that if a localized input pump is scanned across the disordered fiber input facet,the output laser signal follows the transverse position of the pump.Moreover,a uniformly distributed pump across the input facet of the disordered fiber generates a laser signal with very low spatial coherence that can be of practical importance in many optical platforms including image transport with fiber bundles.

Deep-learning cell imaging through Anderson localizing optical fiber

We demonstrate a deep-learning-based fiber imaging system that can transfer real-time artifact-free cell images through a meter-long Anderson localizing optical fiber.The cell samples are illuminated by an incoherent LED light source.A deep convolutional neural network is applied to the image reconstruction process.The network training uses data generated by a setup with straight fiber at room temperature(∼20°C)but can be utilized directly for high-fidelity reconstruction of cell images that are transported through fiber with a few degrees bend or fiber with segments heated up to 50°C.In addition,cell images located several millimeters away from the bare fiber end can be transported and recovered successfully without the assistance of distal optics.We provide evidence that the trained neural network is able to transfer its learning to recover images of cells featuring very different morphologies and classes that are never“seen”during the training process.

Swarm intelligence based clustering and localizing methods for loitering munitions in a satellite denied environment

In the networking of loitering munitions during a battle,clustering and localizing algorithms become a major problem because of their highly dynamic topological structure,incomplete connectivity,and limited energy.This paper proposed swarm intelligence based collaborative localizing,clustering,and routing scheme for an ad hoc network of loitering munitions in a satellite denied environment.A hybrid algorithm was first devised by integrating an improved coyote optimization algorithm with a simplified grey wolf optimizer under the sinusoidal crossover strategy.The performance of this algorithm was considerably improved thanks to integration.On this basis,a swarm intelligence based localizing algorithm was presented.Bounding cubes were created to reduce the initial search space,which effectively lowered the localizing error.Second,an energysaving clustering algorithm based on the hybrid algorithm was put forward to enhance the clustering efficiency by virtue of grey wolf hierarchy.Meanwhile,an analysis model was developed to determine the optimal number of clusters using the lowest possible number of transmissions.Ultimately,a compressed sensing routing scheme based on the hybrid algorithm was proposed to transmit data from a cluster head to a base station.This algorithm constructed an efficient routing tree from the cluster head to the base station,so as to reduce the routing delay and transmission count.As revealed in the results of simulation experiments,the proposed collaborative localizing,clustering and routing algorithms achieved better performance than other popular algorithms employed in various scenarios.

A multi-sensor relation model for recognizing and localizing faults of machines based on network analysis

Recently,advanced sensing techniques ensure a large number of multivariate sensing data for intelligent fault diagnosis of machines.Given the advantage of obtaining accurate diagnosis results,multi-sensor fusion has long been studied in the fault diagnosis field.However,existing studies suffer from two weaknesses.First,the relations of multiple sensors are either neglected or calculated only to improve the diagnostic accuracy of fault types.Second,the localization for multi-source faults is seldom investigated,although locating the anomaly variable over multivariate sensing data for certain types of faults is desirable.This article attempts to overcome the above weaknesses by proposing a global method to recognize fault types and localize fault sources with the help of multi-sensor relations(MSRs).First,an MSR model is developed to learn MSRs automatically and further obtain fault recognition results.Second,centrality measures are employed to analyze the MSR graphs learned by the MSR model,and fault sources are therefore determined.The proposed method is demonstrated by experiments on an induction motor and a centrifugal pump.Results show the proposed method’s validity in diagnosing fault types and sources.

Video Games Localization into Arabic:Gamers’Reactions to Localizing PUBG and Free Fire

The Middle East and North Africa(MENA)region has an active gaming community,with Arab gamers being reliant on games produced in Europe,America,and Japan due to the lack of significant game production companies in the MENA region.This study explores the gamers’reactions to the localization process of two video games,namely PUBG and Free Fire.For data collection purposes,a five-point Likert scale questionnaire that consisted of 18 items and six constructs,namely need for subtitled games,technical aspects,language issues,language preference,attitudes to game localization,and future actions and recommendations,was designed to elicit the reactions of 112 participants.Upon analyzing the responses,the findings showed that the better the technical aspects and language issues of the games’performance,the more positive participants’attitudes to game localization.The study recommends that further research could be conducted on the localization of video games with different themes into Arabic.

Point Cloud Classification Using Content-Based Transformer via Clustering in Feature Space

Recently, there have been some attempts of Transformer in 3D point cloud classification. In order to reduce computations, most existing methods focus on local spatial attention,but ignore their content and fail to establish relationships between distant but relevant points. To overcome the limitation of local spatial attention, we propose a point content-based Transformer architecture, called PointConT for short. It exploits the locality of points in the feature space(content-based), which clusters the sampled points with similar features into the same class and computes the self-attention within each class, thus enabling an effective trade-off between capturing long-range dependencies and computational complexity. We further introduce an inception feature aggregator for point cloud classification, which uses parallel structures to aggregate high-frequency and low-frequency information in each branch separately. Extensive experiments show that our PointConT model achieves a remarkable performance on point cloud shape classification. Especially, our method exhibits 90.3% Top-1 accuracy on the hardest setting of ScanObjectN N. Source code of this paper is available at https://github.com/yahuiliu99/PointC onT.

A study of the effect of local scour on the flow field near the spur dike

The flow field near a spur dike such as down flow and horseshoe vortex system(HVS)are susceptible to the topographic changes in the local scouring process,resulting in variation of the sediment transport with time.In this study,large eddy simulations with fixed-bed at different scouring stages were conducted to investigate the changes in flow field.The results imply that the bed deformation leads to an increase in flow rate per unit area,which represent the capability of sediment transportation by water,in the scour hole.Moreover,the intensity of turbulent kinetic energy and bimodal motion near the sand bed induced by the HVS were also varied.However,the peak moments between the two sediment transport mechanisms were different.Hence,understanding the complex feedback mechanism between topography and flow field is essential for the local scour problem.

Genome-wide investigation to assess copy number variants in the Italian local chicken population

Background Copy number variants(CNV)hold significant functional and evolutionary importance.Numerous ongoing CNV studies aim to elucidate the etiology of human diseases and gain insights into the population structure of livestock.High-density chips have enabled the detection of CNV with increased resolution,leading to the identification of even small CNV.This study aimed to identify CNV in local Italian chicken breeds and investigate their distribution across the genome.Results Copy number variants were mainly distributed across the first six chromosomes and primarily associated with loss type CNV.The majority of CNV in the investigated breeds were of types 0 and 1,and the minimum length of CNV was significantly larger than that reported in previous studies.Interestingly,a high proportion of the length of chromosome 16 was covered by copy number variation regions(CNVR),with the major histocompatibility complex being the likely cause.Among the genes identified within CNVR,only those present in at least five animals across breeds(n=95)were discussed to reduce the focus on redundant CNV.Some of these genes have been associated to functional traits in chickens.Notably,several CNVR on different chromosomes harbor genes related to muscle development,tissue-specific biological processes,heat stress resistance,and immune response.Quantitative trait loci(QTL)were also analyzed to investigate potential overlapping with the identified CNVR:54 out of the 95 gene-containing regions overlapped with 428 QTL associated to body weight and size,carcass characteristics,egg production,egg components,fat deposition,and feed intake.Conclusions The genomic phenomena reported in this study that can cause changes in the distribution of CNV within the genome over time and the comparison of these differences in CNVR of the local chicken breeds could help in preserving these genetic resources.

A Study on the Transmission Dynamics of the Omicron Variant of COVID-19 Using Nonlinear Mathematical Models

This research examines the transmission dynamics of the Omicron variant of COVID-19 using SEIQIcRVW and SQIRV models,considering the delay in converting susceptible individuals into infected ones.The significant delays eventually resulted in the pandemic’s containment.To ensure the safety of the host population,this concept integrates quarantine and the COVID-19 vaccine.We investigate the stability of the proposed models.The fundamental reproduction number influences stability conditions.According to our findings,asymptomatic cases considerably impact the prevalence of Omicron infection in the community.The real data of the Omicron variant from Chennai,Tamil Nadu,India,is used to validate the outputs.

Multi-Material Topology Optimization for Spatial-Varying Porous Structures

This paper aims to propose a topology optimization method on generating porous structures comprising multiple materials.The mathematical optimization formulation is established under the constraints of individual volume fraction of constituent phase or total mass,as well as the local volume fraction of all phases.The original optimization problem with numerous constraints is converted into a box-constrained optimization problem by incorporating all constraints to the augmented Lagrangian function,avoiding the parameter dependence in the conventional aggregation process.Furthermore,the local volume percentage can be precisely satisfied.The effects including the globalmass bound,the influence radius and local volume percentage on final designs are exploited through numerical examples.The numerical results also reveal that porous structures keep a balance between the bulk design and periodic design in terms of the resulting compliance.All results,including those for irregular structures andmultiple volume fraction constraints,demonstrate that the proposedmethod can provide an efficient solution for multiple material infill structures.