Fixture locating layout has a direct and influential impact on aeronautical thin-walled component(ATWC)manufacturing quality.The purpose is to develop a topological optimization method for ATWC fixture locating layout...Fixture locating layout has a direct and influential impact on aeronautical thin-walled component(ATWC)manufacturing quality.The purpose is to develop a topological optimization method for ATWC fixture locating layout to minimize the manufacturing deformation.Firstly,a topological optimization model that takes the stiffness of ATWC as the objective function and the volume of the locating structure as the constraint is established.Secondly,ATWC and the locating structure are regarded as an integrated entity,and the variable-density method based topological optimization approach is adopted for the optimization of the locating structure using ABAQUS topology optimization module(ATOM).Thirdly,through a subsequent model reconstruction referring to the obtained topological structure,the optimal fixture locating layout is achieved.Finally,a case study is conducted to verify the proposed method and the comparison results with firefly algorithm(FA)coupled with finite element analysis(FEA)indicate that the number and positions of the locators for ATWC can be optimized simultaneously and successfully by the proposed topological optimization model.展开更多
In order to solve the problem of how to collect and manage large amount of location information and improve the accuracy of location service, interactive information supporting system based on ontology and location se...In order to solve the problem of how to collect and manage large amount of location information and improve the accuracy of location service, interactive information supporting system based on ontology and location service is presented in this paper. It can transmit special information about users' location to front-end instantaneously, so it is very convenient for their daily life. It makes full use of the available wireless communication, which is easy to arrange and convenient for users.展开更多
Proper fixture design is crucial to obtain the better product quality according to the design specification during the workpiece fabrication. Locator layout planning is one of the most important tasks in the fixture ...Proper fixture design is crucial to obtain the better product quality according to the design specification during the workpiece fabrication. Locator layout planning is one of the most important tasks in the fixture design process. However, the design of a fixture relies heavily on the designerts expertise and experience up to now. Therefore, a new approach to loeator layout determination for workpieces with arbitrary complex surfaces is pro- posed for the first time. Firstly, based on the fuzzy judgment method, the proper locating reference and locator - numbers are determined with consideration of surface type, surface area and position tolerance. Secondly, the lo- cator positions are optimized by genetic algorithm(GA). Finally, a typical example shows that the approach is su- perior to the experiential method and can improve positioning accuracy effectively.展开更多
In equipment integrated logistics support(ILS), the supply capability of spare parts is a significant factor. There are lots of depots in the traditional support system, which makes too many redundant spare parts and ...In equipment integrated logistics support(ILS), the supply capability of spare parts is a significant factor. There are lots of depots in the traditional support system, which makes too many redundant spare parts and causes high cost of support. Meanwhile,the inconsistency among depots makes it difficult to manage spare parts. With the development of information technology and transportation, the supply network has become more efficient. In order to further improve the efficiency of supply-support work and the availability of the equipment system, building a system of one centralized depot with multiple depots becomes an appropriate way.In this case, location selection of the depots including centralized depots and multiple depots becomes a top priority in the support system. This paper will focus on the location selection problem of centralized depots considering ILS factors. Unlike the common location selection problem, depots in ILS require a higher service level. Therefore, it becomes desperately necessary to take the high requirement of the mission into account while determining location of depots. Based on this, we raise an optimal depot location model. First, the expected transportation cost is calculated.Next, factors in ILS such as response time, availability and fill rate are analyzed for evaluating positions of open depots. Then, an optimization model of depot location is developed with the minimum expected cost of transportation as objective and ILS factors as constraints. Finally, a numerical case is studied to prove the validity of the model by using the genetic algorithm. Results show that depot location obtained by this model can guarantee the effectiveness and capability of ILS well.展开更多
Using the spatial structure of the external staggered split-level panel layout,a combined support technology for adjacent roadways was developed and analyzed for a rock bolt and anchor cable mechanism.The influence of...Using the spatial structure of the external staggered split-level panel layout,a combined support technology for adjacent roadways was developed and analyzed for a rock bolt and anchor cable mechanism.The influence of the side rock bolt and anchor cable parameters on the mechanical properties of the anchorage body and the support stress distribution of the lateral coal body were revealed using the FLAC3D software.The optimal support parameters of the side rock bolts and anchor cables were subsequently determined,and the support effect of gob-side entry in a mining scenario was verified.The results show that the support of the side rock bolts and anchor cables improves the mechanical properties and stress state of the anchorage body,producing a good protective effect on the coal body of the air-intake entry roof and side wall.This is beneficial to the stability of the side wall and the realization of the suspension effect for roof rock bolts and anchor cables,which in turn makes the surrounding rock maintenance of the gob-side entry to a thick coal seam more favorable.展开更多
The rapidly increasing number of sequences entering into the genome databank has created the need for fully automated methods to analyze them.Knowing the cellular location of a protein is a key step towards understand...The rapidly increasing number of sequences entering into the genome databank has created the need for fully automated methods to analyze them.Knowing the cellular location of a protein is a key step towards understanding its function.The development in statistical prediction of protein attributes generally consists of two cores: one is to construct a training dataset and the other is to formulate a predictive algorithm.The latter can be further separated into two subcores: one is how to give a mathematical expression to effectively represent a protein and the other is how to find a powerful algorithm to accurately perform the prediction.To predict the subcellular location of eukaryotic protein,a systematic prediction approach comprised of a novel feature extraction method,an idea of combining this feature extraction method with support vector machine(SVM) algorithm,and ’one-versus-rest’ & ’all-versus-all’ strategies have been proposed in this paper.Consequently,the total predictive accuracies reach 95.5% for four locations.Compared with existing methods,this new approach provides better predictive performance.For example,it is 13.5%,5.1% higher than Yuan’s and Hua’s methods respectively.These results demonstrate the applicability of this new method and concept and possible improvement of prediction for the protein subcellular location.It is anticipated that the current approach may also have a series of impacts on the prediction of other protein features.展开更多
In the context of a room-and-pillar mining gob in Shanxi province in China,this paper numerically investigates the stress distribution and deformation rules of roadway surrounding rocks at various locations of residua...In the context of a room-and-pillar mining gob in Shanxi province in China,this paper numerically investigates the stress distribution and deformation rules of roadway surrounding rocks at various locations of residual coal pillars in room-and-pillar mining gobs using software FLAC3 D.It is found that the concentrated stress beneath coal pillars distributes in a shape of ellipse.A reasonable roadway layout is then proposed.In this design,it is indicated that roadways should be designed to avoid the supporting zones of pillars with increasing compression and take into account the roof falling and crushing in the upper gob.According to the surrounding rock deformation characteristics and mining roadway locations as well as the supporting principles of timely support,rock reinforcing,piecewise management and suiting local conditions,a new asymmetric shield supporting plan is proposed.The field surveying results show that this supporting plan can effectively control the roadway rock deformation,thus guarantee the safe and smooth construction of roadways.展开更多
The"three shells"cooperative support technology was proposed herein according to both the large deformation of the rock surrounding large-section chambers in deep mines and the precarious stability of the su...The"three shells"cooperative support technology was proposed herein according to both the large deformation of the rock surrounding large-section chambers in deep mines and the precarious stability of the support structures therein.The development range of the plastic zone in the surrounding rock was controlled by a stress shell to reduce the difficulty of controlling the surrounding rock.Additionally,the residual strength of the rock mass in the plastic zone and the self-bearing capacity of the surrounding rock were improved by a reinforced load-bearing shell.Furthermore,a passive load-bearing shell could restore the triaxial stress state of the surrounding rock on the free surface,reduce the influence of the external environment on the surrounding rock,and reinforce the surrounding rock with the strength of the shell.Reasonable layouts of large-section chambers were determined by analyzing the control effect of the stress shell on the surrounding rock under three kinds of in situ stress fields.The orthogonal test method was applied to reveal the influences of different support parameters in the reinforced loadbearing shell and passive load-bearing shell on the surrounding rock stability.The surrounding rock control effect of the"three shells"collaborative support technology was analyzed through numerical simulation and field monitoring.The results show that the maximum displacement between the roof and floor of the coal preparation chamber in the Xinjulong coal mine was approximately 48 mm,and the maximum displacement between its two sides was approximately 65 mm,indicating that the technology proposed herein could meet the long-term control requirements of the surrounding rock stability for large-section chambers in deep mines.展开更多
Background: Location of death has been used to examine an indicator for good death. This study aims to examine location of death among patients with three major cancers (gastric, liver, and lung) and other factors ass...Background: Location of death has been used to examine an indicator for good death. This study aims to examine location of death among patients with three major cancers (gastric, liver, and lung) and other factors associated with location of death in South Korea. Methods: We selected the medical and pharmacy claims data for health services and location of death among the 42,596 decedents with cancer (lung 16,632, liver 15,872, gastric 10,092) from 2009 to 2013. We used logistic regressions to identify factors associated with home death. Outcome measures are locations of death (hospital, outpatient clinics or emergency room and home). Results: Only 8.9% died at home whereas 46.5% died in hospital as inpatients. Patients with more than one comorbid cancer or receivers for any supportive care were significantly more likely to die in hospital. Female and younger than 55 years old liver cancer patients were associated with home death. Patients living in metropolitan area, or paying more insurance premium, or being public aid beneficiaries, were associated with home death. Conclusions: The supportive care service use prior to death was significantly associated with increasing odds to hospital death. Being older than 75, or having multiple cancers was significant factors associated with hospital death, whereas living in metropolitan area, lower income or emergency visit were significant factors with home death. These findings are opposite to what is found, as the palliative care and hospice is predominantly hospital-centered. The findings emphasize a need to available end-of-life care in community for dying patients.展开更多
Apoptosis proteins have a central role in the development and homeostasis of an organism. These proteins are very important for the understanding the mechanism of programmed cell death, and their function is related t...Apoptosis proteins have a central role in the development and homeostasis of an organism. These proteins are very important for the understanding the mechanism of programmed cell death, and their function is related to their types. The apoptosis proteins are categorized into the following four types: (1) Cytoplasmic protein;(2) Plasma membrane-bound protein;(3) Mitochondrial inner and outer proteins;(4) Other proteins. A novel method, the Hilbert-Huang transform, is applied for predicting the type of a given apoptosis protein with support vector machine. High success rates were obtained by the re-substitute test (98/98=100%), jackknife test (91/98 = 92.9%).展开更多
A k-shortest path based algorithm considering layout density and signal integrity for good buffer candidatelocations is proposed in this paper. Theoretical results for computing the maximal distance betweenbuffers are...A k-shortest path based algorithm considering layout density and signal integrity for good buffer candidatelocations is proposed in this paper. Theoretical results for computing the maximal distance betweenbuffers are derived under the timing, noise and slew rate constraints. By modifying the traditional uniformwire segmenting strategy and considering the impact of tile size on density penalty function, this work proposesk-shortest path algorithm to find the buffer insertion candidate locations. The experiments show thatthe buffers inserted can significantly optimize the design density, alleviate signal degradation, save thenumber of buffers inserted and the overall run time.展开更多
Layout design problem is to determine a suitable arrangement for the departments so that the total costs associated with the flow among departments become least. Single Row Facility Layout Problem, SRFLP, is one of &l...Layout design problem is to determine a suitable arrangement for the departments so that the total costs associated with the flow among departments become least. Single Row Facility Layout Problem, SRFLP, is one of </span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">the </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">layout problems that have many practical applications. This problem and its specific scenarios are often used to model many of the raised issues in the field of facility location. SRFLP is an arrangement of </span><i><span style="font-family:Verdana;">n</span></i><span style="font-family:Verdana;"> departments with a specified length in a straight line so that the sum of the weighted distances between the pairs of departments is minimized. This problem is NP-hard. In this paper, first, a lower bound for a special case of SRFLP is presented. Then, a general </span><span style="font-family:Verdana;">case of SRFLP is presented in which some new and real assumptions are added to generate more practical model. Then a lower bound, as well as an algorithm, is proposed for solving the model. Experimental results on some instances in literature show the efficiency of our algorithm.展开更多
A method is proposed for detecting damage to shear structures by using Support Vector Machine (SVM) and only the first three natural frequencies of the translational modes. This method is able to determine the damage ...A method is proposed for detecting damage to shear structures by using Support Vector Machine (SVM) and only the first three natural frequencies of the translational modes. This method is able to determine the damage location in any story of a shear building with only two vibration sensors;to obtain modal frequencies, one sensor on the ground detects an input and the other on the roof detects the output. Based on the shifts in the first three natural frequencies, damage location indicators are proposed, and used as new feature vectors for SVM. Simulations of five-story, nine-story and twenty-one-story shear structures and experiments on a five-story steel model were used to test the performance of the proposed method.展开更多
基金supported by the National Natural Science Foundation of China(No.51375396)the Shaanxi Science and Technology Innovation Project Plan,China(No.2016KTCQ01-50)
文摘Fixture locating layout has a direct and influential impact on aeronautical thin-walled component(ATWC)manufacturing quality.The purpose is to develop a topological optimization method for ATWC fixture locating layout to minimize the manufacturing deformation.Firstly,a topological optimization model that takes the stiffness of ATWC as the objective function and the volume of the locating structure as the constraint is established.Secondly,ATWC and the locating structure are regarded as an integrated entity,and the variable-density method based topological optimization approach is adopted for the optimization of the locating structure using ABAQUS topology optimization module(ATOM).Thirdly,through a subsequent model reconstruction referring to the obtained topological structure,the optimal fixture locating layout is achieved.Finally,a case study is conducted to verify the proposed method and the comparison results with firefly algorithm(FA)coupled with finite element analysis(FEA)indicate that the number and positions of the locators for ATWC can be optimized simultaneously and successfully by the proposed topological optimization model.
基金funded by the National High Technology Research and Development Program of China (2006AA10Z239)the Key Technologies R&D Program of China during the 11th Five-Year Plan period (2006BAD10A05)
文摘In order to solve the problem of how to collect and manage large amount of location information and improve the accuracy of location service, interactive information supporting system based on ontology and location service is presented in this paper. It can transmit special information about users' location to front-end instantaneously, so it is very convenient for their daily life. It makes full use of the available wireless communication, which is easy to arrange and convenient for users.
基金Supported by the Natural Science Foundation of Jiangxi Province(2009GZC0104)the Science and Technology Research Project of Jiangxi Provincial Department of Education(GJJ10521)~~
文摘Proper fixture design is crucial to obtain the better product quality according to the design specification during the workpiece fabrication. Locator layout planning is one of the most important tasks in the fixture design process. However, the design of a fixture relies heavily on the designerts expertise and experience up to now. Therefore, a new approach to loeator layout determination for workpieces with arbitrary complex surfaces is pro- posed for the first time. Firstly, based on the fuzzy judgment method, the proper locating reference and locator - numbers are determined with consideration of surface type, surface area and position tolerance. Secondly, the lo- cator positions are optimized by genetic algorithm(GA). Finally, a typical example shows that the approach is su- perior to the experiential method and can improve positioning accuracy effectively.
基金supported by the Science Challenge Project(TZ2018007)the National Natural Science Foundation of China(71671009+2 种基金 61871013 61573041 61573043)
文摘In equipment integrated logistics support(ILS), the supply capability of spare parts is a significant factor. There are lots of depots in the traditional support system, which makes too many redundant spare parts and causes high cost of support. Meanwhile,the inconsistency among depots makes it difficult to manage spare parts. With the development of information technology and transportation, the supply network has become more efficient. In order to further improve the efficiency of supply-support work and the availability of the equipment system, building a system of one centralized depot with multiple depots becomes an appropriate way.In this case, location selection of the depots including centralized depots and multiple depots becomes a top priority in the support system. This paper will focus on the location selection problem of centralized depots considering ILS factors. Unlike the common location selection problem, depots in ILS require a higher service level. Therefore, it becomes desperately necessary to take the high requirement of the mission into account while determining location of depots. Based on this, we raise an optimal depot location model. First, the expected transportation cost is calculated.Next, factors in ILS such as response time, availability and fill rate are analyzed for evaluating positions of open depots. Then, an optimization model of depot location is developed with the minimum expected cost of transportation as objective and ILS factors as constraints. Finally, a numerical case is studied to prove the validity of the model by using the genetic algorithm. Results show that depot location obtained by this model can guarantee the effectiveness and capability of ILS well.
基金National Natural Science Foundation of Surface Project of China(Grant Nos.5177428952074291)+2 种基金The National Natural Science Foundation of the Youth Science Foundation of China(Grant No.51404270)The Fundamental Research Funds for the Central Universities(Grant No.2011QZ06)The Open Fund of State Key Laboratory of Coal Resources in Western China(Grant No.SKLCRKF1903).
文摘Using the spatial structure of the external staggered split-level panel layout,a combined support technology for adjacent roadways was developed and analyzed for a rock bolt and anchor cable mechanism.The influence of the side rock bolt and anchor cable parameters on the mechanical properties of the anchorage body and the support stress distribution of the lateral coal body were revealed using the FLAC3D software.The optimal support parameters of the side rock bolts and anchor cables were subsequently determined,and the support effect of gob-side entry in a mining scenario was verified.The results show that the support of the side rock bolts and anchor cables improves the mechanical properties and stress state of the anchorage body,producing a good protective effect on the coal body of the air-intake entry roof and side wall.This is beneficial to the stability of the side wall and the realization of the suspension effect for roof rock bolts and anchor cables,which in turn makes the surrounding rock maintenance of the gob-side entry to a thick coal seam more favorable.
文摘The rapidly increasing number of sequences entering into the genome databank has created the need for fully automated methods to analyze them.Knowing the cellular location of a protein is a key step towards understanding its function.The development in statistical prediction of protein attributes generally consists of two cores: one is to construct a training dataset and the other is to formulate a predictive algorithm.The latter can be further separated into two subcores: one is how to give a mathematical expression to effectively represent a protein and the other is how to find a powerful algorithm to accurately perform the prediction.To predict the subcellular location of eukaryotic protein,a systematic prediction approach comprised of a novel feature extraction method,an idea of combining this feature extraction method with support vector machine(SVM) algorithm,and ’one-versus-rest’ & ’all-versus-all’ strategies have been proposed in this paper.Consequently,the total predictive accuracies reach 95.5% for four locations.Compared with existing methods,this new approach provides better predictive performance.For example,it is 13.5%,5.1% higher than Yuan’s and Hua’s methods respectively.These results demonstrate the applicability of this new method and concept and possible improvement of prediction for the protein subcellular location.It is anticipated that the current approach may also have a series of impacts on the prediction of other protein features.
基金the National 973 Programs of China (No.2014CB046905)the National Natural Science Foundation of China(Nos.51274191 and 51404245)the Doctoral Fund of Ministry of Education(No.20130095110018)
文摘In the context of a room-and-pillar mining gob in Shanxi province in China,this paper numerically investigates the stress distribution and deformation rules of roadway surrounding rocks at various locations of residual coal pillars in room-and-pillar mining gobs using software FLAC3 D.It is found that the concentrated stress beneath coal pillars distributes in a shape of ellipse.A reasonable roadway layout is then proposed.In this design,it is indicated that roadways should be designed to avoid the supporting zones of pillars with increasing compression and take into account the roof falling and crushing in the upper gob.According to the surrounding rock deformation characteristics and mining roadway locations as well as the supporting principles of timely support,rock reinforcing,piecewise management and suiting local conditions,a new asymmetric shield supporting plan is proposed.The field surveying results show that this supporting plan can effectively control the roadway rock deformation,thus guarantee the safe and smooth construction of roadways.
基金This work was supported by the Fundamental Research Funds for the Central Universities(No.2019XKQYMS61).
文摘The"three shells"cooperative support technology was proposed herein according to both the large deformation of the rock surrounding large-section chambers in deep mines and the precarious stability of the support structures therein.The development range of the plastic zone in the surrounding rock was controlled by a stress shell to reduce the difficulty of controlling the surrounding rock.Additionally,the residual strength of the rock mass in the plastic zone and the self-bearing capacity of the surrounding rock were improved by a reinforced load-bearing shell.Furthermore,a passive load-bearing shell could restore the triaxial stress state of the surrounding rock on the free surface,reduce the influence of the external environment on the surrounding rock,and reinforce the surrounding rock with the strength of the shell.Reasonable layouts of large-section chambers were determined by analyzing the control effect of the stress shell on the surrounding rock under three kinds of in situ stress fields.The orthogonal test method was applied to reveal the influences of different support parameters in the reinforced loadbearing shell and passive load-bearing shell on the surrounding rock stability.The surrounding rock control effect of the"three shells"collaborative support technology was analyzed through numerical simulation and field monitoring.The results show that the maximum displacement between the roof and floor of the coal preparation chamber in the Xinjulong coal mine was approximately 48 mm,and the maximum displacement between its two sides was approximately 65 mm,indicating that the technology proposed herein could meet the long-term control requirements of the surrounding rock stability for large-section chambers in deep mines.
文摘Background: Location of death has been used to examine an indicator for good death. This study aims to examine location of death among patients with three major cancers (gastric, liver, and lung) and other factors associated with location of death in South Korea. Methods: We selected the medical and pharmacy claims data for health services and location of death among the 42,596 decedents with cancer (lung 16,632, liver 15,872, gastric 10,092) from 2009 to 2013. We used logistic regressions to identify factors associated with home death. Outcome measures are locations of death (hospital, outpatient clinics or emergency room and home). Results: Only 8.9% died at home whereas 46.5% died in hospital as inpatients. Patients with more than one comorbid cancer or receivers for any supportive care were significantly more likely to die in hospital. Female and younger than 55 years old liver cancer patients were associated with home death. Patients living in metropolitan area, or paying more insurance premium, or being public aid beneficiaries, were associated with home death. Conclusions: The supportive care service use prior to death was significantly associated with increasing odds to hospital death. Being older than 75, or having multiple cancers was significant factors associated with hospital death, whereas living in metropolitan area, lower income or emergency visit were significant factors with home death. These findings are opposite to what is found, as the palliative care and hospice is predominantly hospital-centered. The findings emphasize a need to available end-of-life care in community for dying patients.
文摘Apoptosis proteins have a central role in the development and homeostasis of an organism. These proteins are very important for the understanding the mechanism of programmed cell death, and their function is related to their types. The apoptosis proteins are categorized into the following four types: (1) Cytoplasmic protein;(2) Plasma membrane-bound protein;(3) Mitochondrial inner and outer proteins;(4) Other proteins. A novel method, the Hilbert-Huang transform, is applied for predicting the type of a given apoptosis protein with support vector machine. High success rates were obtained by the re-substitute test (98/98=100%), jackknife test (91/98 = 92.9%).
基金Supported by the National Key Project of Scientific and Technical Supporting Programs (No. 2006BAK07B04).
文摘A k-shortest path based algorithm considering layout density and signal integrity for good buffer candidatelocations is proposed in this paper. Theoretical results for computing the maximal distance betweenbuffers are derived under the timing, noise and slew rate constraints. By modifying the traditional uniformwire segmenting strategy and considering the impact of tile size on density penalty function, this work proposesk-shortest path algorithm to find the buffer insertion candidate locations. The experiments show thatthe buffers inserted can significantly optimize the design density, alleviate signal degradation, save thenumber of buffers inserted and the overall run time.
文摘Layout design problem is to determine a suitable arrangement for the departments so that the total costs associated with the flow among departments become least. Single Row Facility Layout Problem, SRFLP, is one of </span></span><span style="font-family:Verdana;"><span style="font-family:Verdana;"><span style="font-family:Verdana;">the </span></span></span><span><span><span style="font-family:""><span style="font-family:Verdana;">layout problems that have many practical applications. This problem and its specific scenarios are often used to model many of the raised issues in the field of facility location. SRFLP is an arrangement of </span><i><span style="font-family:Verdana;">n</span></i><span style="font-family:Verdana;"> departments with a specified length in a straight line so that the sum of the weighted distances between the pairs of departments is minimized. This problem is NP-hard. In this paper, first, a lower bound for a special case of SRFLP is presented. Then, a general </span><span style="font-family:Verdana;">case of SRFLP is presented in which some new and real assumptions are added to generate more practical model. Then a lower bound, as well as an algorithm, is proposed for solving the model. Experimental results on some instances in literature show the efficiency of our algorithm.
文摘A method is proposed for detecting damage to shear structures by using Support Vector Machine (SVM) and only the first three natural frequencies of the translational modes. This method is able to determine the damage location in any story of a shear building with only two vibration sensors;to obtain modal frequencies, one sensor on the ground detects an input and the other on the roof detects the output. Based on the shifts in the first three natural frequencies, damage location indicators are proposed, and used as new feature vectors for SVM. Simulations of five-story, nine-story and twenty-one-story shear structures and experiments on a five-story steel model were used to test the performance of the proposed method.