A novel dual-channel thermo-optic locking method for the whispering gallery mode microresonator

Mode locking can be effectively achieved by using the thermo-optic effects in the whispering gallery mode(WGM)optical microcavity,without the help of external equipment.Therefore,it has the advantages of small size,low integration costs,and self-locking,which shows great potential for application.However,the conventional single-channel microcavity thermal-locking method that relies solely on internal thermal balance will inevitably be disturbed by the external environment.This limitation affects the locking time and stability.Therefore,in this paper,we propose a new method for closed-loop thermal locking of a dual-channel microcavity.The thermal locking of the signal laser and the thermal regulation of the control laser are carried out respectively by synchronously drawing a dual-path tapered fiber.The theoretical model of the thermal dynamics of the dual-channel microcavity system is established,and the influence of the control-laser power on the thermal locking of the signal laser is confirmed.The deviation between the locking voltage of the signal laser and the set point value is used as a closed-loop feedback parameter to achieve long-term and highly stable mode locking of the signal laser.The results show that in the 2.63 h thermal-locking test,the locking stability is an order of magnitude higher than that of the single tapered fiber.This solution addresses the issue of thermal locking being disrupted by the external environment,and offers new possibilities for important applications such as spectroscopy and micro-optical sensor devices.

Early Treatment Outcome of Humeral Shaft Fracture Non-Union in Adults: Comparative Study of Plating versus Interlocking Nailing

Background: Fractures of humeral shaft in adults are common injuries. Humeral shafts non-union either from late presentation after initial treatment by traditional bone setters or failed non-operative orthodox care is a major problem in this part of the world. This non-union is a major treatment challenge with increased cost of care and morbidity in this part of the world. Humeral shaft non-union can be treated with locked intra-medullary nailing (LIMN) or dynamic compression plating (DCP). Study on comparison of these methods of fixation in this part of the world is scarce in literature search, hence the reason for this study. Objective: The objectives of this study are: (1) to compare early clinical outcome following fixation of humeral shaft fracture nonunion with DCP versus LIMN;(2) to compare the time of radiologic fracture union of DCP with LIMN;(3) to compare complications following fixation of humeral shaft fracture nonunion with DCP versus LIMN. Patients and Methods: This was a randomized control study done for 2 years in which fifty adult patients with humeral shaft non-union were recruited. The patients were grouped into 2 (P = DCP & N = LIMN). Forty five of the patients completed the follow up periods of the study and then analyzed. The P group had ORIF with DCP while the N group had ORIF with LIMN. Both groups had grafting with cancellous bones. Each patient was followed up for a period of 6 months at the time which radiographic union is expected. Any patient without clinical and/or radiographic evidence of union after six months of surgery was diagnosed as having recurrent non-union. The data generated was analyzed using SPSS Version 23. The results were presented in charts and tables. The paired t-test was used while considering p value Result: Forty five patients completed follow up. There was a male preponderance (4:1), right humerus predominated (3:2). Motor vehicular accidents were the commonest cause of the fractures (62%). Most non-union fractures occurred at the level of the middle 3rd of the humeral shaft (60%). Failed TBS treatment was the commonest indication for the osteosynthesis (71%). More patients had plating (53%) compared to 47% who had LIMN. Most patients (93.4%) had union between 3 to 6 months irrespective of fixation type with no significant statistical difference between the union rate of DCP and LIMN (p value 0.06) with similar functional outcome and complication rates irrespective of the type of fixation. Conclusion: This study showed that the success rates in term of fracture union, outcome functional grades and complication rates were not directly dependent on the types of the fixation: plating or locked intra-medullary nailing.

Unlocking Cellular Mysteries:Advancements in Single-Cell Omics Analysis with Genome-Scale Metabolic Modeling

The widespread applications of single-cell technologies have generated a large amount of single-cell data,resulting in a growing need for single-cell data analysis and interpretation methods.While methods such as machine learning allow for single-cell data analysis,they cannot interpret the data very well.

克服“Locking”发散性的有限元研究进展

从克服Ｌｏｃｋｉｎｇ发散性到高性能格式的研究发展是过去十年有限元法研究的一个重要方面．本文认为所谓高性能有限元方法是一种特别的低阶位移格式，它具有如下的理论和计算优点：（１）保持物理力学问题固有的数学物理特征；（２）因此，应用于工程数值模拟，它是“鲁棒”的、高效的．按此立场，评论介绍了在计算结构力学和计算流体力学中发展的克服两类Ｌｏｃｋｉｎｇ发散性的有限元方法．

Volar locking distal radius plates show better short-term results than other treatment options: A prospective randomised controlled trial

AIM To compare the outcomes of displaced distal radius fractures treated with volar locking plates and with immediate postoperative mobilisation with the outcomes of these fractures treated with modalities that necessitate 6 wk wrist immobilisation.METHODS A prospective, randomised controlled single-centre trial was conducted with 56 patients who had a displaced radius fracture were randomised to treatment either with a volar locking plate(n = 29), or another treatment modality(n = 27; cast immobilisation with or without wires or external fixator). Outcomes were measured at 12 wk. Functional outcome scores measured were the Patient-Rated Wrist Evaluation(PRWE) Score; Disabilities of the Arm, Shoulder and Hand and activities of daily living(ADLs). Clinical outcomes were wrist range of motion and grip strength. Radiographic parameters were volar inclination and ulnar variance.RESULTS Patients in the volar locking plate group had significantly better PRWE scores, ADL scores, grip strength and range of extension at three months compared with the control group. All radiological parameters were significantly better in the volar locking plate group at 3 mo. CONCLUSION The present study suggests that volar locking plates produced significantly better functional and clinical outcomes at 3 mo compared with other treatment modalities. Anatomical reduction was significantly more likely to be preserved in the plating group. Level of evidence: Ⅱ.

Structure Analysis of Locking Mechanism of Gear-Rack Typed Ship-Lift

Contact nonlinear theory was researched. Contact problem was transformed into optimization problem containing Lagrange multiplier, and unsymmetrical stiffness matrix was transformed into symmetrical stiffness matrix. A finite element analysis （FEA） model defining more than 300 contact pairs for long nut-short screw locking mechanism of a large-scale vertical gear-rack typed ship-lift was built. Using augmented Lagrange method and symmetry algorithm of contact element stiffness, the FEA model was analyzed, and the contact stress of contact interfaces and the von Mises stress of key parts were obtained. The results show that the design of the locking mechanism meets the requirement of engineering, and this method is effective for solving large stole nonlinear contact pairs.

Locking compression plate+T-type steel plate for postoperative weight bearing and functional recovery in complex tibial plateau fractures

Complex tibial plateau fractures can seriously affect quality of life and physical and mental health of patients.The anatomical relationship between the proximal tibial bone and soft tissue is complex,resulting in different types of tibial plateau fractures.Violent trauma can lead to displaced fracture,serious soft tissue injury,and potentially,dislocation of the knee joint.Therefore,tibial plateau fractures are extremely unstable.AIM To assess the use of locking compression plate(LCP)+T-type steel plate for postoperative weight bearing and functional recovery of complex tibial plateau fractures.METHODS Ninety-seven patients with complex tibial plateau fractures who underwent surgery at our hospital were selected for retrospective study.Forty-nine patients had been treated with LCP+T-type steel plate limited internal fixation(study group),and 48 patients with bilateral ordinary steel plate support(control group).The operation process index,postoperative rehabilitation related index,Rasmussen score of the knee joint,tibial plateau varus angle(TPA),tibial plateau retroversion angle(PA),and surgical complications of the two groups were compared.RESULTS The operation time and intraoperative bone graft volume in the study group were lower than those in the control group(P<0.05).There were no significant differences in surgical bleeding,anterior external incision length,postoperative drainage,hospital stay duration,and fracture healing time between the groups(P>0.05).There was no significant difference in the TPA and PA angle between the groups immediately and 18 mo after surgery(P>0.05).At 12 mo after surgery,the Rasmussen scale score was higher in the study group than in the control group(P<0.05).There was no significant difference in the Rasmussen scale score at 18 mo after surgery,and the radiology score at 12 and 18 mo after surgery,between the two groups(P>0.05).The postoperative complication rate in the study group(3.77%)was lower than that in the control group(15.09%;P<0.05).CONCLUSION LCP+T-type steel plate internal fixation has advantages in terms of minimizing trauma and enabling early postoperative functional exercise,promoting functional recovery and lower limb weight-bearing,and reducing postoperative complications.

Simulation and Analysis of Flexible Solar Panels' Deployment and Locking Processes

To predict the attitude of satellite during the whole deployment process and evaluate the locking impact, a numerical flexible model of a certain satellite associated with four flexible honeycomb solar panels was established. The flexible solar panel was modeled by the finite element analysis (FEA), and the motion equations were derived by Lagrangian formulation. The locking process was based on the method of Hertzian contact, which enables one to predict the locking impact on the satellite and the subsequent oscillation of solar panels. The results reveal that locking operation has great impact on the attitude of the satellite, and the angular acceleration of satellite reaches 22.03°/s2 at the locking moment; the flexible solar panels model is feasible to predict the accurate response of the satellite during deployment and the oscillation of solar panels; the instantly impulsive force occurred during locking process is about 1.5 kN and the changing time is nearly 0.32 s. It provides an effective approach to present the flexible solar panels' deployment process and evaluate the locking impact.

Theory of Dynamics In-Phase Locking and Quasi-Period Synchronization in Two Mutually Coupled Multi-Quantum-Well Lasers

Abstract We study dynamics in two mutually coupling multi-quantum-well lasers. We carry out theoretical and numerical analysis of synchronization, anti-synchronization, in-phase locking in the two identical lasers but detuning, in detain. It is proved that the coupling level determines stability of the lasers by analyzing the eigenvalue equation. Critical case of locking is discussed via the phase difference equation. Quasi-period and stable states in the two lasers are investigated via varying the current, detuning and coupling level.

Transition state to mode locking in a passively mode-locked erbium-doped fibre ring laser

The transition state between the continuous wave region and the mode-locked region in a passively mode-locked erbium-doped fibre ring laser has been experimentally observed by utilizing the nonlinear polarization rotation technique. When the pump power reaches the mode-locked threshold, the metastable pulse train with a tunable repetition rate is obtained in the transition from the continuous wave state to the passive mode-locked state via proper adjustment of the polarization controller. A simpie model has been established to explain the experimental observation.

Four corner fusion using a multidirectional angular stable locking plate

AIM: To review the results of our experience with the Medartis Aptus plating system for four corner arthrodesis of the wrist, which uses a combination of compression screws and variable angle locking screws.METHODS: We reviewed the results of 17 procedures in 16 patients that underwent scaphoid excision and four corner fusion using the Medartis Aptus system between May 2010 and June 2014. The primary outcome measure was radiographic and clinical union. RESULTS: The mean clinical follow up time was 20.6 mo. The mean union time was 6 mo. Two non-unions required revision procedures. The mean disabilities of the arm, shoulder and hand score taken after union was 36. The mean final grip strength was 27 kg. The mean final range of movement was 30° flexion and 31° of extension. All patients had a restored scapholunate angle on postoperative radiographs. There were no incidences of dorsal impingement.CONCLUSION: Overall our experience with the Aptus plating system shows comparable results to other methods of fixation for four corner fusion, in the short to medium term.

Coherent Beam Combining of Two Slab Laser Amplifiers and Second-Harmonic Phase Locking Based on a Multi-Dithering Technique

Coherent beam combining(CBC)is an efficient way to scale the brightness of laser arrays.We demonstrate the active phase locking CBC of two slab laser amplifiers based on the multi-dithering technique.The experimental investigation on the 102 W coherent beam combining of two slab amplifiers shows that the whole system in a closed loop performs well over a long time observation.The contrast of the coherent combined beam profile is about 87%and the combining efficiency is nearly 85%.In addition,the CBC of two green lasers is realized based on the second-harmonic generation of the phase locking pump lasers.To the best of our knowledge,this is the first report about second-harmonic active phase locking,which indicates further potential applications of CBC.

Screw placement is everything: Risk factors for loss of reduction with volar locking distal radius plates

AIM To determine factors correlated with postoperative radial shortening in patients with distal radius fractures treated with volar locking distal radius plates.METHODS A total of 250 patients with a distal radius fracture stabilised with volar locking plates between January 2010 and December 2014 were included in a multicentre retrospective cohort study. We measured the distance of the distal locking screws to the joint line immediately postoperatively and then measured radial shortening after six to eight weeks using the change in ulnar variance.RESULTS Multivariate linear regression analysis showed that there was a significant linear association between the distance of the screws from the joint line and radial shortening. No other patient, injury, or treatment-related characteristic significantly influenced radial shortening in multivariate analysis.CONCLUSION Distal locking screws should be placed as close as possible to the subchondral joint line to prevent postoperative loss of reduction.

Locking of Tearing Modes by the Error Field

The locking of tearing modes by the error field is studied by nonlinear numerical modeling.The threshold of mode locking for J-TEXT tokamak plasmas is found.

Laser frequency locking based on Rydberg electromagnetically induced transparency

We present a laser frequency locking to Rydberg transition with electromagnetically induced transparency（EIT）spectra in a room-temperature cesium vapor cell. Cesium levels 6S_（1/2）, 6P_（3/2）, and the n D_（5/2） state, compose a cascade three-level system, where a coupling laser drives Rydberg transition, and probe laser detects the EIT signal. The error signal, obtained by demodulating the EIT signal, is used to lock the coupling laser frequency to Rydberg transition. The laser frequency fluctuation, ~0.7 MHz, is obtained after locking on, with the minimum Allan variance to be 8.9 × 10^（-11）.This kind of locking method can be used to stabilize the laser frequency to the excited transition.

Geodetic slip rate and locking depth of east Semangko Fault derived from GPS measurement

65 km Semangko Fault is part of southern segments of Sumatran Fault Zone(SFZ)which is complex corresponds to the transition from the strike-slip regime of the SFZ to the normal faulting tectonics of the Sunda Strait.The recent publication showed branches of Semangko Fault:West Semangko Fault(WSF)and East Semangko Fault(ESF).This study estimated geodetic slip rate and locking depth of ESF using Global Positioning System(GPS)time series data from 2007 to 2019 from all available GPS sites.GPS velocities refer to Sundaland Plate were used to estimate the fault parameters of the WSF and ESF simultaneously.Non-uniformity of velocity direction shows the complexities of Semangko Fault possibly caused by the contribution of all faults around ESF.An ESF geodetic slip rate,which is 12.5±2 mm/yr was lower than WSF,which is 16.5±2 mm/yr.It is consistent with the rigid block nature of the SFZ system as northern segment slip rates have similar value.Small slip rates are possibly leading to lower generated seismic moment than the major segment of SFZ.

On the Mechanism of the Locking of the El Nino Event Onset Phase to Boreal Spring

The mechanism of the locking of the E1 Nino event onset phase to boreal spring （from April to June） in an intermediate coupled ocean-atmosphere model is investigated. The results show that the seasonal variation of the zonal wind anomaly over the equatorial Pacific associated with the seasonal variation of the ITCZ is the mechanism of the locking in the model. From January to March of the E1 Nino year, the western wind anomaly over the western equatorial Pacific can excite the downwelling Kelvin wave that propagates eastward to the eastern and middle Pacific by April to June. From April to December of the year before the E1 Nifio year, the eastern wind anomaly over the equatorial Pacific forces the downwelling Rossby waves that modulate the ENSO cycle. The modulation and the reflection at the western boundary modulate the time of the transition from the cool to the warm phase to September of the year before the E1 Nifio year and cause the strongest downwelling Kelvin wave from the reflected Rossby waves at the western boundary to arrive in the middle and eastern equatorial Pacific by April to June of the E1 Nino year. The superposition of these two kinds of downwelling Kelvin waves causes the El Nino event to tend to occur from April to June.

Seasonal Phase-Locking of Peak Events in the Eastern Indian Ocean

The sea surface temperature （SST） anomaly of the eastern Indian Ocean （EIO） exhibits cold anomalies in the boreal summer or fall during E1 Nino development years and warm anomalies in winter or spring following the E1 Nino events. There also tend to be warm anomalies in the boreal summer or fall during La Nina development years and cold anomalies in winter or spring following the La Nina events. The seasonal phase-locking of SST change in the EIO associated with E1 Nino/Southern Oscillation is linked to the variability of convection over the maritime continent, which induces an atmospheric Rossby wave over the EIO. Local air-sea interaction exerts different effects on SST anomalies, depending on the relationship between the Rossby wave and the mean flow related to the seasonal migration of the buffer zone, which shifts across the equator between summer and winter. The summer cold events start with cooling in the Timor Sea, together with increasing easterly flow along the equator. Negative SST anomalies develop near Sumatra, through the interaction between the atmospheric Rossby wave and the underneath sea surface. These SST anomalies are also contributed to by the increased upwelling of the mixed layer and the equatorward temperature advection in the boreal fall. As the buffer zone shifts across the equator towards boreal winter, the anomalous easterly flow tends to weaken the mean flow near the equator, and the EIO SST increases due to the reduction of latent heat flux from the sea surface. As a result, wintertime SST anomalies appear with a uniform and nearly basin-wide pattern beneath the easterly anomalies. These SST anomalies are also caused by the increase in solar radiation associated with the anticyclonic atmospheric Rossby wave over the EIO. Similarly, the physical processes of the summer warm events, which are followed by wintertime cold SST anomalies, can be explained by the changes in atmospheric and oceanic fields with opposite signs to those anomalies described above.

Modeling Locking Angle of the Multi-layered Biaxial Weft Knitted Fabric in Shear Deformation

This paper introduces the construction of the multi-layered biaxial weft knitted fabric （MBWK fabric） and studies the locking angle of this kind of fabric. Moreover, a locking angle model of the MBWK fabric is established for the first time according to its unique construction. Two kinds of locking angles are considered under different restraint conditions: the locking angle θ1 controlled by the inserting yarns and the locking angle θ2 controlled by the stitch yarns. It is concluded that the ultimate value of the locking angle θ is the larger one of the two angles.

Heparin versus Saline Solution for Locking of Totally Implantable Venous Access Port (TIVAP): Cohort Study of the First Kurdistan Series of TIVAP

Introduction: Totally implantable venous access port (TIVAP) is essential prerequisite for most of chemotherapy protocols. Flushing with 0.9% sodium chloride becomes an alternative to heparinized solution. As flushing and locking solutions are still controversial, this study was conducted to compare efficacy of heparinized solution versus normal saline solution for locking in ports TIVAP. Patients and Methods: Prospective Cohort study performed in teaching hospital Sulaymaniyah-University of Kurdistan, Iraq, including 384 TIVAP implanted in cancer and non-cancer patients. The study reports the TIVAP outcome in 2 groups of patients where 2 different solutions used for maintaining catheter’s patency by heparinized solution in group (A), versus normal saline for group (B). Results: In group A, the rate of complications was 8.2% (n = 16) while in group B complications rate was 7.9% (n = 15). Thrombosis in group A occurred in 1.03% of the cases and in group B was 1.57%. There were no significant differences between the two groups regarding the causes for unwanted removals of the TIVAP. Conclusions: The results of our study suggest that heparin has no role in preventing the early or late complications of TIVAP and we do not recommend using it as a locking solution.