Evolution model and failure mechanisms of rainfall-induced cracked red clay slopes:insights from Xinshao County,China

Red clay landslides are widely distributed worldwide,resulting in severe loss of life and property.Although rainfall-induced red clay slopes have received extensive attention,the role of cracks in the evolutionary process of red clay slopes and their connection to failure mechanisms is still poorly understood.A comprehensive approach integrating field investigation,laboratory tests,and numerical simulations was conducted to study the 168 red clay landslides in Xinshao County,China.The results show that red clay is prone to forming cracks at high moisture content due to its low swelling and high shrinkage properties.The failure mode of red clay slopes can be summarized in three stages:crack generation,slope excavation,and slope failure.Furthermore,the retrospective analysis and numerical simulations of the typical landslide in Guanchong indicated that intense rainfall primarily impacts the shallow layer of soil within approximately 0.5 m on the intact slope.However,cracks change the pattern of rainfall infiltration in the slope.Rainwater infiltrates rapidly through the preferential channels induced by the cracks rather than uniformly and slowly from the slope surface.This results in a significant increase in both the depth of infiltration and the saturated zone area of the cracked slope,reaching 3.8 m and 36.2 m^(2),respectively.Consequently,the factor of safety of the slope decreases by 13.4%compared to the intact slope,ultimately triggering landslides.This study can provide valuable insights into understanding the failure mechanisms of red clay slopes in China and other regions with similar geological settings.

Experimental studies and failure mechanisms of strain andfault-slip rockburst:A review

In recent years,rockburst have gained significant attention as a crucial topic in rock engineering.Strain andfault-slip rockburst are two common types that occur frequently and cause substantial damage.The objective of thisreview is to conduct a comprehensive study on the experiments and failure mechanisms of strain and fault-slip rockburst.Firstly,the article analyzes the evolving trends in experimental research on rockburst in the past decade,highlightingmechanical properties and failure modes as the primary research focuses in understanding rockburst mechanisms.Subsequently,it provides an overview of the experimental techniques and methods employed for studying both types ofrockburst.Then,with a focus on the mechanical properties and failure modes,the article conducts an extensive analysisof the failure mechanisms associated with strain and fault-slip rockburst.By analyzing experimental data and observingthe failure characteristics of samples,it discusses the variations and common features exhibited by these two types ofrockburst under various test conditions.This analysis is of paramount importance in revealing the causes of rockburstformation and development,as well as in predicting rockburst trends and assessing associated risks.Lastly,thelimitations of current rockburst experiments and future research directions are discussed,followed by a comprehensivesummary of the entire article.

A review of extreme condition effects on solder joint reliability:Understanding failure mechanisms

Solder joint,crucial component in electronic systems,face significant challenges when exposed to extreme conditions during applications.The solder joint reliability involving microstructure and mechanical properties will be affected by extreme conditions.Understanding the behaviour of solder joints under extreme conditions is vital to determine the durability and reliability of solder joint.This review paper aims to comprehensively explore the underlying failure mechanism affecting solder joint reliability under extreme conditions.This study covers an in-depth analysis of effect extreme temperature,mechanical stress,and radiation conditions towards solder joint.Impact of each condition to the microstructure including solder matrix and intermetallic compound layer,and mechanical properties such as fatigue,shear strength,creep,and hardness was thoroughly discussed.The failure mechanisms were illustrated in graphical diagrams to ensure clarity and understanding.Furthermore,the paper highlighted mitigation strategies that enhancing solder joint reliability under challenging operating conditions.The findings offer valuable guidance for researchers,engineers,and practitioners involved in electronics,engineering,and related fields,fostering advancements in solder joint reliability and performance.

Failure mechanism and infrared radiation characteristic of hard siltstone induced by stratification effect

The deformation in sedimentary rock induced by train loads has potential threat to the safe operation of tunnels. This study investigated the influence of stratification structure on the infrared radiation and temporal damage mechanism of hard siltstone. The uniaxial compression tests, coupled with acoustic emission(AE) and infrared radiation temperature(IRT) were conducted on siltstones with different stratification effects. The results revealed that the stratigraphic structure significantly affects the stress-strain response and strength degradation characteristics. The mechanical parameters exhibit anisotropy characteristics, and the stratification effect exhibits a negative correlation with the cracking stress and peak stress. The failure modes caused by the stratification effect show remarkable anisotropic features, including splitting failure(Ⅰ: 0°-22.50°, Ⅱ: 90°), composite failure(45°), and shearing failure(67.50°). The AE temporal sequences demonstrate a stepwise response characteristic to the loading stress level. The AE intensity indicates that the stress sensitivity of shearing failure and composite failure is generally greater than that of splitting failure. The IRT field has spatiotemporal migration and progressive dissimilation with stress loading and its dissimilation degree increases under higher stress levels. The stronger the stratification effect, the greater the dissimilation degree of the IRT field. The abnormal characteristic points of average infrared radiation temperature(AIRT) variance at local stress drop and peak stress can be used as early and late precursors to identify fracture instability. Theoretical analysis shows that the competitive relationship between compaction strengthening and fracturing damage intensifies the dissimilation of the infrared thermal field for an increasing stress level. The present study provides a theoretical reference for disaster warnings in hard sedimentary rock mass.

Pressure stimulated current in progressive failure process of combined coal-rock under uniaxial compression:Response and mechanism

Effective monitoring of the structural health of combined coal-rock under complex geological conditions by pressure stimulated currents(PSCs)has great potential for the understanding of dynamic disasters in underground engineering.To reveal the effect of this way,the uniaxial compression experiments with PSC monitoring were conducted on three types of coal-rock combination samples with different strength combinations.The mechanism explanation of PSCs are investigated by resistivity test,atomic force microscopy(AFM)and computed tomography(CT)methods,and a PSC flow model based on progressive failure process is proposed.The influence of strength combinations on PSCs in the progressive failure process are emphasized.The results show the PSC responses between rock part,coal part and the two components are different,which are affected by multi-scale fracture characteristics and electrical properties.As the rock strength decreases,the progressive failure process changes obviously with the influence range of interface constraint effect decreasing,resulting in the different responses of PSC strength and direction in different parts to fracture behaviors.The PSC flow model is initially validated by the relationship between the accumulated charges of different parts.The results are expected to provide a new reference and method for mining design and roadway quality assessment.

Mechanism of principal stress rotation and deformation failure behavior induced by excavation in roadways

The failure modes of rock after roadway excavation are diverse and complex.A comprehensive investigation of the internal stress field and the rotation behavior of the stress axis in roadways is essential for elucidating the mechanism of roadway failure.This study aimed to examine the spatial relationship between roadways and stress fields.The law of stress axis rotation under three-dimensional(3D)stress has been extensively studied.A stress model of roadways in the spatial stress field was established,and the far-field stress state at different spatial positions of the roadways was analyzed.A mechanical model of roadways under a 3D stress state was established using far-field stress solutions as boundary conditions.The distribution of principal stressesσ1,σ2 andσ3 around the roadways and the variation of the stress principal axis were solved.It was found that the stability boundary of the stress principal axis exhibits hysteresis when compared with that of the principal stress magnitudes.A numerical analysis model for spatial roadways was established to validate the distribution of principal stress and the mechanism of principal axis rotation.Research has demonstrated that the stress axis undergoes varying degrees of spatial rotation in different orientations and radial depths.Based on the distribution of principal stress and the rotation law of the stress principal axis,the entire evolution mechanism of the two stress adjustments to form the final failure form after roadway excavation has been revealed.The on-site detection results also corroborate the findings presented in this paper.The results provide a basis for the analysis of the failure mechanism under a 3D stress state.

Recent advances in quantifying the inactive lithium and failure mechanism of Li anodes in rechargeable lithium metal batteries

Lithium metal is considered as the ultimate anode material for the next generation of high-energy density batteries.However,non-uniform lithium dendrite growth,serious electrolyte consumption,and significant volume changes during lithium deposition/stripping processes lead to sustained accumulation of inactive lithium and poor cycling reversibility.Quantifying the formation and evolution of inactive lithium under different conditions and fully evaluating the complex failure modes are the key issues in this challenging field.This article comprehensively reviews recent research progress on the quantification of formation and evolution of inactive lithium detected by different quantitative techniques in rechargeable lithium metal batteries.The key research challenges such as failure mechanism,modification strategies and operando characterization of lithium metal anodes are systematically summarized and prospected.This review provides a new angle of view to understand failure mechanism of lithium metal anodes and inspiration and guidance for the future development of rechargeable lithium metal batteries.

Short-circuit failure modes and mechanism investigation of 1200 V planar SiC MOSFETs

This paper presents a comprehensive analysis of the short-circuit failure mechanisms in commercial 1.2 kV planar sili-con carbide(SiC)metal–oxide–semiconductor field-effect transistors(MOSFETs)under 400 and 800 V bus voltage conditions.The study compares two products with varying short-circuit tolerances,scrutinizing their external characteristics and intrinsic fac-tors that influence their short-circuit endurance.Experimental and numerical analyses reveal that at 400 V,the differential ther-mal expansion between the source metal and the dielectric leads to cracking,which in turn facilitates the infiltration of liquid metal and results in a gate–source short circuit.At 800 V,the failure mechanism is markedly different,attributed to the ther-mal carrier effect leading to the degradation of the gate oxide,which impedes the device's capacity to switch off,thereby trig-gering thermal runaway.The paper proposes strategies to augment the short-circuit robustness of SiC MOSFETs at both volt-age levels,with the objective of fortifying the device's resistance to such failures.

Failure mechanism of directional roof cutting and design method optimization

Directional roof cutting(DRC)is one of the key techniques in non-pillar coal mining with self-formed entries(NCMSE)mining method.Due to the inability to accurately measure the expansion coefficient of the goaf rock mass,the implementation of this technology often encounters design challenges,leading to suboptimal results and increased costs.This paper establishes a structural analysis model of the goaf working face roof,revealing the failure mechanism of DRC,and clarifies the positive role of DRC in improving the stress of the roadway surrounding rock and reducing the subsidence of the roof through numerical simulation experiments.On this basis,the paper further analyses the roadway pressure and roof settlement under different DRC design heights,and ultimately proposes an optimized design method for the DRC height.The results indicate that the implementation of DRC can significantly optimize the stress environment of the working face roadway surrounding rock.At the same time,during the application of DRC,three scenarios may arise:insufficient,reasonable,and excessive DRC height.Insufficient height will significantly reduce the effectiveness of the technology,while excessive height has little impact on the implementation effect but will greatly increase construction costs and difficulty.Engineering verification shows that the optimized DRC design method proposed in this paper reduces the peak stress of the protective coal pillar in the roadway by 27.2%and the central subsidence of the roof by 41.8%,demonstrating excellent application results.This method provides technical support for the further promotion of NCMSE mining method.

Ground response and failure mechanism of gob-side entry by roof cutting with hard main roof

This study is the result of long-term efforts of the authors’team to assess ground response of gob-side entry by roof cutting(GSERC)with hard main roof,aiming at scientific control for GSERC deformation.A comprehensive field measurement program was conducted to determine entry deformation,roof fracture zone,and anchor bolt(cable)loading.The results indicate that GSERC deformation presents asymmetric characteristics.The maximum convergence near roof cutting side is 458 mm during the primary use process and 1120 mm during the secondary reuse process.The entry deformation is closely associated with the primary development stage,primary use stage,and secondary reuse stage.The key block movement of roof cutting structure,a complex stress environment,and a mismatch in the supporting design scheme are the failure mechanism of GSERC.A controlling ideology for mining states,including regional and stage divisions,was proposed.Both dynamic and permanent support schemes have been implemented in the field.Engineering practice results indicate that the new support scheme can efficiently ensure long-term entry safety and could be a reliable approach for other engineering practices.

Investigation on the mechanism of Qiangxinhuoli prescription in the treatment of chronic heart failure based on p38-MAPK signaling pathway

Background:The aim of this study is to investigate the mechanism of action underlying the therapeutic effects of the national patent Chinese medicine compound“Qiangxinhuoli prescription(QXHLF)”on chronic heart failure(CHF).Methods:In vitro,the H_(9)C_(2) cell model was induced by ANGII,and cell proliferation and related protein expression were detected by Cell Counting Kit-8 and Western blot.In vivo,A rat model of CHF was prepared by ligation of the left anterior descending coronary artery.The effects of QXHLF on cardiac function in CHF rats were evaluated by cardiac index,hemodynamic changes,enzyme-linked immunosorbent assay,hematoxylin-eosin staining,immunohistochemistry,Western blot and RT-PCR.The expression of pro-apoptotic factors and anti-apoptotic factors,as well as TGFβ1,p-p38,TAK 1 mRNA,and protein,were detected.Results:In vitro,QXHLF has a significant inhibitory effect on the proliferation of H_(9)C_(2) cells.QXHLF can reduce the expression levels of TAK 1,TGFβ1,p-p38,Caspase3 and BAX proteins in H_(9)C_(2) cells,and increase the expression level of BCL_(2) protein.In vivo,QXHLF has the potential to increase left ventricular systolic pressure,m aximum rate of change in left ventricular pressure while decreasing left ventricular end diastolic pressure,and inhibiting the serum levels of brain natriuretic peptide.Moreover,QXHLF exhibits significant improvements in the pathological alterations of myocardial cells and fibers in CHF rats,leading to enhanced myocardial tissue morphology and notable advantages in combating myocardial fibrosis.QXHLF can reduce the levels of BAX and Caspase3 and up-regulate the expression of BCL_(2),thereby inhibiting cardiomyocyte apoptosis.Furthermore,QXHLF demonstrates inhibitory effects on the mRNA and protein expression levels of TGFβ_(1),TAK_(1),and p-p38 in the heart tissue of the CHF rat model.Conclusion:These findings indicate that QXHLF has a therapeutic effect on CHF by inhibiting the p38-MAPK signaling pathway,reducing myocardial fibrosis,preventing apoptosis,inhibiting cell proliferation,and restoring myocardial injury.

Clinical prediction scores predicting weaning failure from invasive mechanical ventilation:Role and limitations

Invasive mechanical ventilation(IMV)has become integral to modern-day critical care.Even though critically ill patients frequently require IMV support,weaning from IMV remains an arduous task,with the reported weaning failure(WF)rates being as high as 50%.Optimizing the timing for weaning may aid in reducing time spent on the ventilator,associated adverse effects,patient discomfort,and medical care costs.Since weaning is a complex process and WF is often multifactorial,several weaning scores have been developed to predict WF and aid decision-making.These scores are based on the patient's physiological and ventilatory parameters,but each has limitations.This review highlights the current role and limitations of the various clinical prediction scores available to predict WF.

Mechanisms of support failure and prevention measures under double-layer room mining gobs——A case study: Shigetai coal mine

In the practice of mining shallow buried ultra-close seams,support failure tends to occur during the process of longwall undermining beneath two layers of room mining goaf(TLRMG).In this paper,the factors causing support failure are summarized into geology and mining technology.Combining column lithology and composite beam theory,the key stratum of the rock strata is determined.A finite element numerical simulation is used to analyze the overlying load distribution rule of the main roof for different plane positions of the upper and lower room mining pillars.The tributary area theory(TAT)is adopted to analyze the vertical load distribution of each pillar,and dynamic models of coal pillar instability and main roof fracture are established.Through key block instability analysis,two critical moments are established,of which critical moment A has the greater dynamic load strength.Great economic losses and safety hazards are created by the dynamic load of the fracturing of the main roof.To reduce these negative effects,a method of pulling out supports is developed and two alternative measures for support failure prevention are proposed:reinforcing stope supports in conjunction with reducing mining height,or drilling ground holes to pre-split the main roof.Based on a comprehensive consideration of economic factors and the two categories of support failure causes,the method of reinforcing stope supports while reducing mining height was selected for use on the mining site.

Seismic failure mechanisms for loaded slopes with associated and nonassociated flow rules

Seismic failure mechanisms were investigated for soil slopes subjected to strip load with upper bound method of limit analysis and finite difference method of numerical simulation,considering the influence of associated and nonassociated flow rules.Quasi-static representation of soil inertia effects using a seismic coefficient concept was adopted for seismic failure analysis.Numerical study was conducted to investigate the influences of dilative angle and earthquake on the seismic failure mechanisms for the loaded slope,and the failure mechanisms for different dilation angles were compared.The results show that dilation angle has influences on the seismic failure surfaces,that seismic maximum displacement vector decreases as the dilation angle increases,and that seismic maximum shear strain rate decreases as the dilation angle increases.

Dynamic tensile strength and failure mechanisms of thermally treated sandstone under dry and water-saturated conditions

To study the tensile strength and failure mechanisms of rock with hydro-thermal coupling damage under different loading rates,a series of static and dynamic splitting tests were conducted on thermally treated sandstone under dry and water-saturated conditions.Experimental results showed that high temperatures effectively weakened the tensile strength of sandstone specimens,and the P-wave velocity declined with increasing temperature.Overall,thermal damage of rock increased gradually with increasing temperature,but obvious negative damage appeared at the temperature of 100℃.The water-saturated sandstone specimens had lower indirect tensile strength than the dry ones,which indicated that water-rock interaction led to secondary damage in heat-treated rock.Under both dry and water-saturated conditions,the dynamic tensile strength of sandstone increased with the increase of strain rate.The water-saturated rock specimens showed stronger rate dependence than the dry ones,but the loading rate sensitivity of thermally treated rock decreased with increasing treatment temperature.With the help of scanning electron microscopy technology,the thermal fractures of rock,caused by extreme temperature,were analyzed.Hydro-physical mechanisms of sandstone under different loading rate conditions after heat treatment were further discussed.

Sodium-glucose cotransporter 2 inhibitors’ mechanisms of action in heart failure

Three major cardiovascular outcome trials(CVOTs)with a new class of antidiabetic drugs-sodium-glucose cotransporter 2(SGLT2)inhibitors(EMPAREG OUTCOME trial with empagliflozin,CANVAS Program with canagliflozin,DECLARE-TIMI 58 with dapagliflozin)unexpectedly showed that cardiovascular outcomes could be improved possibly due to a reduction in heart failure risk,which seems to be the most sensitive outcome of SGLT2 inhibition.No other CVOT to date has shown any significant benefit on heart failure events.Even more impressive findings came recently from the DAPA-HF trial in patients with confirmed and well-treated heart failure:Dapagliflozin was shown to reduce heart failure risk for patients with heart failure with reduced ejection fraction regardless of diabetes status.Nevertheless,despite their possible wide clinical implications,there is much doubt about the mechanisms of action and a lot of questions to unravel,especially now when their benefits translated to nondiabetic patients,rising doubts about the validity of some current mechanistic assumptions.The time frame of their cardiovascular benefits excludes glucoselowering and antiatherosclerotic-mediated effects and multiple other mechanisms,direct cardiac as well as systemic,are suggested to explain their early cardiorenal benefits.These are:Anti-inflammatory,antifibrotic,antioxidative,antiapoptotic properties,then renoprotective and hemodynamic effects,attenuation of glucotoxicity,reduction of uric acid levels and epicardial adipose tissue,modification of neurohumoral system and cardiac fuel energetics,sodiumhydrogen exchange inhibition.The most logic explanation seems that SGLT2 inhibitors timely target various mechanisms underpinning heart failure pathogenesis.All the proposed mechanisms of their action could interfere with evolution of heart failure and are discussed separately within the main text.

Review of clinical characteristics,immune responses and regulatory mechanisms of hepatitis E-associated liver failure

Hepatitis E virus(HEV)is the most common cause of acute liver failure(LF)and one of the most common factors causing acute injury in acute-on-chronic LF(ACLF).When HEV-related LF occurs,a series of changes take place in both the intrahepatic environment and extrahepatic microenvironment.The changed types and distribution of immune cells(infiltrating macrophages and increased lymphocytes)in liver tissue,as well the increased proinflammatory cytokines and chemokines in the blood,indicate that the occurrence and progression of HEVrelated LF are closely related to immune imbalance.The clinical features and immune reaction in the body during HEV-related acute LF(ALF)and ACLF are complicated.This review highlights recent progress in elucidating the clinical manifestations of HEV-associated ALF and ACLF and discusses the corresponding systemic immune changes and possible regulatory mechanisms.

Numerical modeling of failure mechanisms in phyllite mine slopes in Brazil

This paper presents three case studies comprising failure mechanisms in phyllite mine slopes at Quadrila- tero Ferrifero, State of Minas Gerais, Brazil. Numerical modeling techniques were used in this study. Fail- ure mechanisms involving discontinuities sub parallel to the main foliation are very common in these mines. Besides, failure through the rock material has also been observed due to the low strength of phyl- lites in this site. Results of this work permitted to establish unknown geotechnical parameters which have significant influence in failure processes, like the in situ stress field and the discontinuity stiffness.

Comprehensive analyses of initiation and failure mechanisms of the 2017 Xinmo catastrophic rockslide

The failure of the 2017 Xinmo catastrophic rockslide in Maoxian County, Sichuan, Southwest China was a combined effect of long-term and shortterm triggering factors. Field investigation, historical data collection, laboratory tests, chemical and microstructure analysis and numerical simulations were adopted herein to reveal the initiation and failure mechanism of the Xinmo rockslide. The analytical results showed that this failure involved the coupling of several triggering factors. The initial cracks in the rock mass were induced by historical earthquakes due to the convex topography and the direction effect. Rock masses from the source area of the Xinmo rockslide contain water-sensitive minerals, i.e., albite and chamosite, and the easily oxidized chemical element Fe, resulting in obvious strength deterioration under the action of water. The scanning electron microscopy(SEM) experimental results indicated that the internal structure of the rock mass is conducive to weathering. The compressive and shear strengths of the rock mass were reduced due to freeze-thaw cycles and weathering. The antecedent rainfall further deteriorated the stability of the slope, and stress and deformation accumulated continually in the locked section. Finally, the locked section sheared out, and the slope failed. An entrainment effect was observed in the Xinmo rockslide due to the presence of old landslide deposits and the antecedent rainfall, resulting in an amplification of the catastrophic rockslide. A simplified three dimensional analysis model was established in this study to reveal the influence of the triggering factors on the failure mechanism of the Xinmo rockslide.

Characterization of Failure Mechanisms of Duplex and Graded Thermal Barrier Coatings Exposed to Thermal Shock Test

The beginning of failure of a (ZrO2-7%Y2O3)/(Ni-22%Co-17%Cr-12.5%Al-0.6%Y) duplex andgraded coating systems on lnconel 617 and IN738LC in burner rig tests has been characterized.The test conditions are 40 s heating up to 75O℃ substrate temperature followed by 80 s aircooling. Failure is considered at the appearance of the first bright spot during heating period.Stresses due to thermal expansion mismatch strains on cooling are the probable cause of life-limiting in this conditions of testing.