Bedding structural planes significantly influence the mechanical properties and stability of engineering rock masses.This study conducts uniaxial compression tests on layered sandstone with various bedding angles(0...Bedding structural planes significantly influence the mechanical properties and stability of engineering rock masses.This study conducts uniaxial compression tests on layered sandstone with various bedding angles(0°,15°,30°,45°,60°,75°and 90°)to explore the impact of bedding angle on the deformational mechanical response,failure mode,and damage evolution processes of rocks.It develops a damage model based on the Logistic equation derived from the modulus’s degradation considering the combined effect of the sandstone bedding dip angle and load.This model is employed to study the damage accumulation state and its evolution within the layered rock mass.This research also introduces a piecewise constitutive model that considers the initial compaction characteristics to simulate the whole deformation process of layered sandstone under uniaxial compression.The results revealed that as the bedding angle increases from 0°to 90°,the uniaxial compressive strength and elastic modulus of layered sandstone significantly decrease,slightly increase,and then decline again.The corresponding failure modes transition from splitting tensile failure to slipping shear failure and back to splitting tensile failure.As indicated by the modulus’s degradation,the damage characteristics can be categorized into four stages:initial no damage,damage initiation,damage acceleration,and damage deceleration termination.The theoretical damage model based on the Logistic equation effectively simulates and predicts the entire damage evolution process.Moreover,the theoretical constitutive model curves closely align with the actual stress−strain curves of layered sandstone under uniaxial compression.The introduced constitutive model is concise,with fewer parameters,a straightforward parameter determination process,and a clear physical interpretation.This study offers valuable insights into the theory of layered rock mechanics and holds implications for ensuring the safety of rock engineering.展开更多
The dynamic parameter identification of the robot is the basis for the design of the controller based on the dynamic model.Currently,the primary method for solving angular velocity and angular acceleration is to filte...The dynamic parameter identification of the robot is the basis for the design of the controller based on the dynamic model.Currently,the primary method for solving angular velocity and angular acceleration is to filter and smooth the position sequence and then form a differential signal.However,if the noise and the original signal overlap in the frequency domain,filtering the noise will also filter out the valuable information in the frequency band.This paper proposes an excitation trajectory based on Logistic function,which fully uses the information in the original signal and can accurately solve the angular velocity and angular acceleration without filtering and smoothing the position sequence.The joint angle of the excitation trajectory is mapped to the joint angular velocity and angular acceleration one by one so that the joint angular velocity and joint angular acceleration can be obtained directly according to the position.The genetic algorithm is used to optimize the excitation trajectory parameters to minimize the observation matrix’s condition number and further improve the identification accuracy.By using the strategy of iterative identification,the dynamic parameters identified in each iteration are substituted into the robot controller according to the previous position sequence until the tracking trajectory approaches the desired trajectory,and the actual joint angular velocity and angular acceleration converge to the expected value.The simulation results show that using the step-by-step strategy,the joint angular velocity and joint angular acceleration of the tracking trajectory quickly converge to the expected value,and the identification error of inertia parameters is less than 0.01 in three iterations.With the increase of the number of iterations,the identification error of inertial parameters can be further reduced.展开更多
The seasonality and randomness of wind present a significant challenge to the operation of modern power systems with high penetration of wind generation. An effective shortterm wind power prediction model is indispens...The seasonality and randomness of wind present a significant challenge to the operation of modern power systems with high penetration of wind generation. An effective shortterm wind power prediction model is indispensable to address this challenge. In this paper, we propose a combined model, i.e.,a wind power prediction model based on multi-class autoregressive moving average(ARMA). It has a two-layer structure: the first layer classifies the wind power data into multiple classes with the logistic function based classification method;the second layer trains the prediction algorithm in each class. This two-layer structure helps effectively tackle the seasonality and randomness of wind power while at the same time maintaining high training efficiency with moderate model parameters. We interpret the training of the proposed model as a solvable optimization problem. We then adopt an iterative algorithm with a semi-closed-form solution to efficiently solve it. Data samples from open-source projects demonstrate the effectiveness of the proposed model. Through a series of comparisons with other state-of-the-art models, the experimental results confirm that the proposed model improves not only the prediction accuracy,but also the parameter estimation efficiency.展开更多
Voluntary participation of hemiplegic patients is crucial for functional electrical stimulation therapy.A wearable functional electrical stimulation system has been proposed for real-time volitional hand motor functio...Voluntary participation of hemiplegic patients is crucial for functional electrical stimulation therapy.A wearable functional electrical stimulation system has been proposed for real-time volitional hand motor function control using the electromyography bridge method.Through a series of novel design concepts,including the integration of a detecting circuit and an analog-to-digital converter,a miniaturized functional electrical stimulation circuit technique,a low-power super-regeneration chip for wireless receiving,and two wearable armbands,a prototype system has been established with reduced size,power,and overall cost.Based on wrist joint torque reproduction and classification experiments performed on six healthy subjects,the optimized surface electromyography thresholds and trained logistic regression classifier parameters were statistically chosen to establish wrist and hand motion control with high accuracy.Test results showed that wrist flexion/extension,hand grasp,and finger extension could be reproduced with high accuracy and low latency.This system can build a bridge of information transmission between healthy limbs and paralyzed limbs,effectively improve voluntary participation of hemiplegic patients,and elevate efficiency of rehabilitation training.展开更多
Coronavirus disease 2019 outbreak has spread as a pandemic since the end of year 2019.This situation has been causing a lot of problems of human beings such as economic problems,health problems.The forecasting of the ...Coronavirus disease 2019 outbreak has spread as a pandemic since the end of year 2019.This situation has been causing a lot of problems of human beings such as economic problems,health problems.The forecasting of the number of infectious people is required by the authorities of all countries including Southeast Asian countries to make a decision and control the outbreak.This research is to investigate the suitable forecasting model for the number of infectious people in Southeast Asian countries.A comparison of forecasting models between logistic growth curve which is symmetric and Gompertz growth curve which is asymmetric based on the maximumof Coefficient of Determination and theminimumof RootMean Squared Percentage Error is also proposed.The estimation of parameters of the forecasting models is evaluated by the least square method.In addition,spreading of the outbreak is estimated by the derivative of the number of cumulative cases.The findings show that Gompertz growth curve is a suitable forecasting model for Indonesia,Philippines,andMalaysia and logistic growth curve suits the other countries in South Asia.展开更多
The response of Kousa dogwood (Cornus kousa Buerg.) to extreme stresses was investigated by RGB image analysis in the hot, dry and windy summer in 2007 in Yamaguch, Japan. Results show that tip and margin leaf scorc...The response of Kousa dogwood (Cornus kousa Buerg.) to extreme stresses was investigated by RGB image analysis in the hot, dry and windy summer in 2007 in Yamaguch, Japan. Results show that tip and margin leaf scorch was observed on many Kousa dogwood trees and clearly dark brown defense barrier appeared on scorched leaves. The defense barrier withdrew back from distal to proximal gradually until successful control of scorching, and left a series of unsuccessful defense traces. By responsive analysis of leaf color homogeneity with RGB image analysis method, a sharp logistic equation was obtained for the relative green/luminance (RGL) value of scorched leaves. By the meteorological analysis, the occurrence of dogwood leaf scorch-back was almost synchronous with the aridity peak period. It sug- gested that during the sudden aridity increment the extreme water stresses induce the defense response of Kousa dogwood tree to shear the excessive transpiration leaf area, and prevent the rest of the trees from further water loss. Image pixet analysis showed that 40.2% leaf area of sampled dogwood trees was reduced through the partial leaf scorch-back by the end of August in 2007. In contrast, only 13.2% leaf area was reduced from the same trees in 2008, for the reason of sufficient precipitation during first half year. In any case, the Kousa dogwood trees indeed reduced their transpiration surface area and appeared a surface reduction pattern differing from those shedding leaves or withering all the aboveground. Based on desiccation process analysis, it is considered that the interaction of the leaf dried back and the self-defense response was the key of the transpiration surface reduction (TSR) of Kousa dogwood during sudden hot and droughty stresses.展开更多
The wind power potential in Interior Alaska is evaluated from a micrometeorological perspective. Based on the local balance equation of momentum and the equation of continuity we derive the local balance equation of k...The wind power potential in Interior Alaska is evaluated from a micrometeorological perspective. Based on the local balance equation of momentum and the equation of continuity we derive the local balance equation of kinetic energy for macroscopic and turbulent systems, and in a further step, Bernoulli’s equation and integral equations that customarily serve as the key equations in momentum theory and blade-element analysis, where the Lanchester-Betz-Joukowsky limit, Glauert’s optimum actuator disk, and the results of the blade-element analysis by Okulov and Sorensen are exemplarily illustrated. The wind power potential at three different sites in Interior Alaska (Delta Junction, Eva Creek, and Poker Flat) is assessed by considering the results of wind field predictions for the winter period from October 1, 2008, to April 1, 2009 provided by the Weather Research and Forecasting (WRF) model to avoid time-consuming and expensive tall-tower observations in Interior Alaska which is characterized by a relatively low degree of infrastructure outside of the city of Fairbanks. To predict the average power output we use the Weibull distributions derived from the predicted wind fields for these three different sites and the power curves of five different propeller-type wind turbines with rated powers ranging from 2 MW to 2.5 MW. These power curves are represented by general logistic functions. The predicted power capacity for the Eva Creek site is compared with that of the Eva Creek wind farm established in 2012. The results of our predictions for the winter period 2008/2009 are nearly 20 percent lower than those of the Eva Creek wind farm for the period from January to September 2013.展开更多
Theoretical frequencies of green area index (GAI) measurements were assessed in order to bring out the optimum frequencies for the monitoring of the senescence of winter wheat as well as the relationships between me...Theoretical frequencies of green area index (GAI) measurements were assessed in order to bring out the optimum frequencies for the monitoring of the senescence of winter wheat as well as the relationships between metrics which could be derived and the final grain yield. Several profiles of GAI decreasing curves were elaborated based on field measurements. Two functions, usually employed in green leaf area decreasing curves fitting (i.e., modified Gompertz and logistic functions) were then used to characterize the senescence phase and to calculate their metrics. These analyses showed that the two curve fitting functions satisfactorily described the senescence phase on frequencies of four to six GAI measurements, well distributed throughout a period of 30-35 days. The regression-based modeling showed that those involving metrics from logistic function (i.e., maximum value of GAI, green area duration and senescent rate) were more suitable than that of the modified Gompertz function for wheat yield estimates. Such results could be useful for studies at larger scales (involving remote sensing airplane or satellite data) and focused on the senescence in terms of optimum number of measurements and frequencies for developing models for yield estimates.展开更多
Antibody dependant enhancement refers that viral infectivity was unexpectedly enhanced at low antibody concentration compared to when antibodies were absent,such as Dengue,Zika and influenza virus.To mathematically de...Antibody dependant enhancement refers that viral infectivity was unexpectedly enhanced at low antibody concentration compared to when antibodies were absent,such as Dengue,Zika and influenza virus.To mathematically describe switch from enhancement to neutralisation with increase of antibody concentration,one hyperbolic tangent variant is used as switching function in existed models.However,switching function with hyperbolic tangent contains four parameters,and does not always increase with antibody concentration.To address this problem,we proposed a monotonically increasing Logistical function variant as switching function,which only contains position parameter and magnitude parameter.Analysing influenza viral titre estimated from 21 focus reduction assay(FRA)datasets from neutralisation group(viral titre lower than negative control on all serial dilutions)and 20 FRA dataset from enhancement group(viral titre higher than negative control on high serial dilution),switching function with Logistic function performs better than existed model independent of both groups and exhibited different behaviour/character;specifically,magnitude parameter estimated from enhancement group is lower,but position parameter estimated from enhancement group is higher.A lower magnitude parameter refers that enhancement group more rapidly switches from enhancement to neutralisation with increase of antibody concentration,and a higher position parameter indicates that enhancement group provides a larger antibody concentration interval corresponding to enhancement.Integrating estimated neutralisation kinetics with viral replication,we demonstrated that antibody-induced bistable influenza kinetics exist independent of both groups.However,comparing with neutralisation group,enhancement group provides higher threshold value of antibody concentration corresponding to influenza infectivity.This explains the observed phenomenon that antibody dependent enhancement enhances susceptibility,severity,and mortality to influenza infection.On population level,antibody dependant enhancement can promote H1N1 and H3N2 influenza virus cooperate to sustain long-term circulation on human populations according to antigenic seniority theory.展开更多
MicroRNAs(miRNAs)exert an enormous influence on cell differentiation,biological development and the onset of diseases.Because predicting potential miRNA-disease associations(MDAs)by biological experiments usually requ...MicroRNAs(miRNAs)exert an enormous influence on cell differentiation,biological development and the onset of diseases.Because predicting potential miRNA-disease associations(MDAs)by biological experiments usually requires considerable time and money,a growing number of researchers are working on developing computational methods to predict MDAs.High accuracy is critical for prediction.To date,many algorithms have been proposed to infer novel MDAs.However,they may still have some drawbacks.In this paper,a logistic weighted profile-based bi-random walk method(LWBRW)is designed to infer potential MDAs based on known MDAs.In this method,three networks(i.e.,a miRNA functional similarity network,a disease semantic similarity network and a known MDA network)are constructed first.In the process of building the miRNA network and the disease network,Gaussian interaction profile(GIP)kernel is computed to increase the kernel similarities,and the logistic function is used to extract valuable information and protect known MDAs.Next,the known MDA matrix is preprocessed by the weighted K-nearest known neighbours(WKNKN)method to reduce the number of false negatives.Then,the LWBRW method is applied to infer novel MDAs by bi-randomly walking on the miRNA network and the disease network.Finally,the predictive ability of the LWBRW method is confirmed by the average AUC of 0.9393(0.0061)in 5-fold cross-validation(CV)and the AUC value of 0.9763 in leave-one-out cross-validation(LOOCV).In addition,case studies also show the outstanding ability of the LWBRW method to explore potential MDAs.展开更多
In view of the fact that the follow-up search for an optimal topology is affected by deleting a large number of high-relative-density elements. When the typical density interpolation approach, namely, solid isotropic ...In view of the fact that the follow-up search for an optimal topology is affected by deleting a large number of high-relative-density elements. When the typical density interpolation approach, namely, solid isotropic microstructures with penalization (SIMP), is employed in the continuum structural topology optimization, a new density interpolation approach based on the logistic function is proposed in this paper. This method can weaken low-relative-density elements while enhancing high-relative-density elements by polarization, and then rationally realize polarization of the intermediate density elements. It can reduce the number of gray-scale elements as much as possible to get the optimal topology with distinct boundaries in conjunction with the sensitivity filtering method based on particle swarm optimization (PSO). Several typical numerical examples are given to demonstrate this method.展开更多
Two major challenges associated with avibration-based damage detection method using changes in natural frequencies are addressed:accurate modeling of structures and the development of a robust inverse algorithm to det...Two major challenges associated with avibration-based damage detection method using changes in natural frequencies are addressed:accurate modeling of structures and the development of a robust inverse algorithm to detect damage,which are defined as the forward and inverse problems,respectively.To resolve the forward problem,new physics-based finite element modeling techniques are developed for fillets in thin-walled beams and for bolted joints,so that complex structures can be accurately modeled with a reasonable model size.To resolve the inverse problem,a logistic function transformation is introduced to convert the constrained optimization problem to an unconstrained one,and a robust iterative algorithm using the Levenberg–Marquardt method is developed to accurately detect the locations and extent of damage.The new methodology can ensure global convergence of the iterative algorithm in solving under--determined system equations and deal with damage detection problems with relatively large modeling error and measurement noise.It is applied to various engineering structures including lightning masts,a space frame structure and one of its components,and a pipeline.The exact locations and extent of damage can be detected in the numerical simulation,and the locations and extent of damage can be successfully detected in experimental damage detection.展开更多
We analysed the data collected for herbaceous peony cultivated in a warm climate region and stored in winter under three constant chilling temperatures.We used the quadratic regression model to describe the stem elong...We analysed the data collected for herbaceous peony cultivated in a warm climate region and stored in winter under three constant chilling temperatures.We used the quadratic regression model to describe the stem elongation responses to winter dormancy conditions,and the logistic function to describe the weekly stems elongation.The predicted maximal stem length from the first model was used as the input parameter for the second model.More than 4000 data for various(a)chilling constant temperatures during dormancy,(b)dormancy duration,and(c)germination duration,were used.The models were applied to determine the optimal number of chill units.For this purpose,two criteria were used in different versions of the model:the maximal stem length and the maximal profit of farmers.For the two chilling temperatures of 2℃ and 6℃,the optimal values of chill units(in the models of a maximal stem length and maximal profit of farmers)are close to one another,and the values of a maximal stem length and maximal profit are significantly different.In the case of the third chilling temperature of 10℃,the model failed to determine the optimal number of chill units.The method of inverse confidence intervals for testing the significance of the optimal number of chill units was used.展开更多
基金Projects(52074299,41941018)supported by the National Natural Science Foundation of ChinaProject(2023JCCXSB02)supported by the Fundamental Research Funds for the Central Universities,China。
文摘Bedding structural planes significantly influence the mechanical properties and stability of engineering rock masses.This study conducts uniaxial compression tests on layered sandstone with various bedding angles(0°,15°,30°,45°,60°,75°and 90°)to explore the impact of bedding angle on the deformational mechanical response,failure mode,and damage evolution processes of rocks.It develops a damage model based on the Logistic equation derived from the modulus’s degradation considering the combined effect of the sandstone bedding dip angle and load.This model is employed to study the damage accumulation state and its evolution within the layered rock mass.This research also introduces a piecewise constitutive model that considers the initial compaction characteristics to simulate the whole deformation process of layered sandstone under uniaxial compression.The results revealed that as the bedding angle increases from 0°to 90°,the uniaxial compressive strength and elastic modulus of layered sandstone significantly decrease,slightly increase,and then decline again.The corresponding failure modes transition from splitting tensile failure to slipping shear failure and back to splitting tensile failure.As indicated by the modulus’s degradation,the damage characteristics can be categorized into four stages:initial no damage,damage initiation,damage acceleration,and damage deceleration termination.The theoretical damage model based on the Logistic equation effectively simulates and predicts the entire damage evolution process.Moreover,the theoretical constitutive model curves closely align with the actual stress−strain curves of layered sandstone under uniaxial compression.The introduced constitutive model is concise,with fewer parameters,a straightforward parameter determination process,and a clear physical interpretation.This study offers valuable insights into the theory of layered rock mechanics and holds implications for ensuring the safety of rock engineering.
基金supported by Aeronautical Science Foundation of China(No.201916052001)China National Key R&D Program(No.2018YFB1309203)Foundation of the Graduate Innovation Center,Nanjing University of Aeronautics and Astronautics(No.xcxjh20210501)。
文摘The dynamic parameter identification of the robot is the basis for the design of the controller based on the dynamic model.Currently,the primary method for solving angular velocity and angular acceleration is to filter and smooth the position sequence and then form a differential signal.However,if the noise and the original signal overlap in the frequency domain,filtering the noise will also filter out the valuable information in the frequency band.This paper proposes an excitation trajectory based on Logistic function,which fully uses the information in the original signal and can accurately solve the angular velocity and angular acceleration without filtering and smoothing the position sequence.The joint angle of the excitation trajectory is mapped to the joint angular velocity and angular acceleration one by one so that the joint angular velocity and joint angular acceleration can be obtained directly according to the position.The genetic algorithm is used to optimize the excitation trajectory parameters to minimize the observation matrix’s condition number and further improve the identification accuracy.By using the strategy of iterative identification,the dynamic parameters identified in each iteration are substituted into the robot controller according to the previous position sequence until the tracking trajectory approaches the desired trajectory,and the actual joint angular velocity and angular acceleration converge to the expected value.The simulation results show that using the step-by-step strategy,the joint angular velocity and joint angular acceleration of the tracking trajectory quickly converge to the expected value,and the identification error of inertia parameters is less than 0.01 in three iterations.With the increase of the number of iterations,the identification error of inertial parameters can be further reduced.
基金supported by the Guangdong-Macao Joint Funding Project(No. 2021A0505080015)Science and Technology Planning Project of Guangdong Province (No. 2019B010137006)Science and Technology Development Fund,Macao SAR (No. SKL-IOTSC(UM)-2021-2023)。
文摘The seasonality and randomness of wind present a significant challenge to the operation of modern power systems with high penetration of wind generation. An effective shortterm wind power prediction model is indispensable to address this challenge. In this paper, we propose a combined model, i.e.,a wind power prediction model based on multi-class autoregressive moving average(ARMA). It has a two-layer structure: the first layer classifies the wind power data into multiple classes with the logistic function based classification method;the second layer trains the prediction algorithm in each class. This two-layer structure helps effectively tackle the seasonality and randomness of wind power while at the same time maintaining high training efficiency with moderate model parameters. We interpret the training of the proposed model as a solvable optimization problem. We then adopt an iterative algorithm with a semi-closed-form solution to efficiently solve it. Data samples from open-source projects demonstrate the effectiveness of the proposed model. Through a series of comparisons with other state-of-the-art models, the experimental results confirm that the proposed model improves not only the prediction accuracy,but also the parameter estimation efficiency.
基金supported by the National Natural Science Foundation of China,No.90307013,90707005,61534003the Science&Technology Pillar Program of Jiangsu Province in China,No.BE2013706
文摘Voluntary participation of hemiplegic patients is crucial for functional electrical stimulation therapy.A wearable functional electrical stimulation system has been proposed for real-time volitional hand motor function control using the electromyography bridge method.Through a series of novel design concepts,including the integration of a detecting circuit and an analog-to-digital converter,a miniaturized functional electrical stimulation circuit technique,a low-power super-regeneration chip for wireless receiving,and two wearable armbands,a prototype system has been established with reduced size,power,and overall cost.Based on wrist joint torque reproduction and classification experiments performed on six healthy subjects,the optimized surface electromyography thresholds and trained logistic regression classifier parameters were statistically chosen to establish wrist and hand motion control with high accuracy.Test results showed that wrist flexion/extension,hand grasp,and finger extension could be reproduced with high accuracy and low latency.This system can build a bridge of information transmission between healthy limbs and paralyzed limbs,effectively improve voluntary participation of hemiplegic patients,and elevate efficiency of rehabilitation training.
基金The research was funding by King Mongkut’s University of Technology North Bangkok Contract No.KMUTNB-61-GOV-03-23.
文摘Coronavirus disease 2019 outbreak has spread as a pandemic since the end of year 2019.This situation has been causing a lot of problems of human beings such as economic problems,health problems.The forecasting of the number of infectious people is required by the authorities of all countries including Southeast Asian countries to make a decision and control the outbreak.This research is to investigate the suitable forecasting model for the number of infectious people in Southeast Asian countries.A comparison of forecasting models between logistic growth curve which is symmetric and Gompertz growth curve which is asymmetric based on the maximumof Coefficient of Determination and theminimumof RootMean Squared Percentage Error is also proposed.The estimation of parameters of the forecasting models is evaluated by the least square method.In addition,spreading of the outbreak is estimated by the derivative of the number of cumulative cases.The findings show that Gompertz growth curve is a suitable forecasting model for Indonesia,Philippines,andMalaysia and logistic growth curve suits the other countries in South Asia.
文摘The response of Kousa dogwood (Cornus kousa Buerg.) to extreme stresses was investigated by RGB image analysis in the hot, dry and windy summer in 2007 in Yamaguch, Japan. Results show that tip and margin leaf scorch was observed on many Kousa dogwood trees and clearly dark brown defense barrier appeared on scorched leaves. The defense barrier withdrew back from distal to proximal gradually until successful control of scorching, and left a series of unsuccessful defense traces. By responsive analysis of leaf color homogeneity with RGB image analysis method, a sharp logistic equation was obtained for the relative green/luminance (RGL) value of scorched leaves. By the meteorological analysis, the occurrence of dogwood leaf scorch-back was almost synchronous with the aridity peak period. It sug- gested that during the sudden aridity increment the extreme water stresses induce the defense response of Kousa dogwood tree to shear the excessive transpiration leaf area, and prevent the rest of the trees from further water loss. Image pixet analysis showed that 40.2% leaf area of sampled dogwood trees was reduced through the partial leaf scorch-back by the end of August in 2007. In contrast, only 13.2% leaf area was reduced from the same trees in 2008, for the reason of sufficient precipitation during first half year. In any case, the Kousa dogwood trees indeed reduced their transpiration surface area and appeared a surface reduction pattern differing from those shedding leaves or withering all the aboveground. Based on desiccation process analysis, it is considered that the interaction of the leaf dried back and the self-defense response was the key of the transpiration surface reduction (TSR) of Kousa dogwood during sudden hot and droughty stresses.
基金the National Science Foundation for funding the project work of Megan Hinzman and Samuel Smock in summer 2011Hannah K.Ross and John Cooney in summer 2012 through the Research Experience for Undergraduates(REU)Program,grant number AGS1005265the Alaska Department of Labor for funding Dr.Gary Sellhorst’s project work
文摘The wind power potential in Interior Alaska is evaluated from a micrometeorological perspective. Based on the local balance equation of momentum and the equation of continuity we derive the local balance equation of kinetic energy for macroscopic and turbulent systems, and in a further step, Bernoulli’s equation and integral equations that customarily serve as the key equations in momentum theory and blade-element analysis, where the Lanchester-Betz-Joukowsky limit, Glauert’s optimum actuator disk, and the results of the blade-element analysis by Okulov and Sorensen are exemplarily illustrated. The wind power potential at three different sites in Interior Alaska (Delta Junction, Eva Creek, and Poker Flat) is assessed by considering the results of wind field predictions for the winter period from October 1, 2008, to April 1, 2009 provided by the Weather Research and Forecasting (WRF) model to avoid time-consuming and expensive tall-tower observations in Interior Alaska which is characterized by a relatively low degree of infrastructure outside of the city of Fairbanks. To predict the average power output we use the Weibull distributions derived from the predicted wind fields for these three different sites and the power curves of five different propeller-type wind turbines with rated powers ranging from 2 MW to 2.5 MW. These power curves are represented by general logistic functions. The predicted power capacity for the Eva Creek site is compared with that of the Eva Creek wind farm established in 2012. The results of our predictions for the winter period 2008/2009 are nearly 20 percent lower than those of the Eva Creek wind farm for the period from January to September 2013.
文摘Theoretical frequencies of green area index (GAI) measurements were assessed in order to bring out the optimum frequencies for the monitoring of the senescence of winter wheat as well as the relationships between metrics which could be derived and the final grain yield. Several profiles of GAI decreasing curves were elaborated based on field measurements. Two functions, usually employed in green leaf area decreasing curves fitting (i.e., modified Gompertz and logistic functions) were then used to characterize the senescence phase and to calculate their metrics. These analyses showed that the two curve fitting functions satisfactorily described the senescence phase on frequencies of four to six GAI measurements, well distributed throughout a period of 30-35 days. The regression-based modeling showed that those involving metrics from logistic function (i.e., maximum value of GAI, green area duration and senescent rate) were more suitable than that of the modified Gompertz function for wheat yield estimates. Such results could be useful for studies at larger scales (involving remote sensing airplane or satellite data) and focused on the senescence in terms of optimum number of measurements and frequencies for developing models for yield estimates.
文摘Antibody dependant enhancement refers that viral infectivity was unexpectedly enhanced at low antibody concentration compared to when antibodies were absent,such as Dengue,Zika and influenza virus.To mathematically describe switch from enhancement to neutralisation with increase of antibody concentration,one hyperbolic tangent variant is used as switching function in existed models.However,switching function with hyperbolic tangent contains four parameters,and does not always increase with antibody concentration.To address this problem,we proposed a monotonically increasing Logistical function variant as switching function,which only contains position parameter and magnitude parameter.Analysing influenza viral titre estimated from 21 focus reduction assay(FRA)datasets from neutralisation group(viral titre lower than negative control on all serial dilutions)and 20 FRA dataset from enhancement group(viral titre higher than negative control on high serial dilution),switching function with Logistic function performs better than existed model independent of both groups and exhibited different behaviour/character;specifically,magnitude parameter estimated from enhancement group is lower,but position parameter estimated from enhancement group is higher.A lower magnitude parameter refers that enhancement group more rapidly switches from enhancement to neutralisation with increase of antibody concentration,and a higher position parameter indicates that enhancement group provides a larger antibody concentration interval corresponding to enhancement.Integrating estimated neutralisation kinetics with viral replication,we demonstrated that antibody-induced bistable influenza kinetics exist independent of both groups.However,comparing with neutralisation group,enhancement group provides higher threshold value of antibody concentration corresponding to influenza infectivity.This explains the observed phenomenon that antibody dependent enhancement enhances susceptibility,severity,and mortality to influenza infection.On population level,antibody dependant enhancement can promote H1N1 and H3N2 influenza virus cooperate to sustain long-term circulation on human populations according to antigenic seniority theory.
基金This work was supported by the National Natural Science Foundation of China under Grant Nos.61902215,61872220 and 61701279.
文摘MicroRNAs(miRNAs)exert an enormous influence on cell differentiation,biological development and the onset of diseases.Because predicting potential miRNA-disease associations(MDAs)by biological experiments usually requires considerable time and money,a growing number of researchers are working on developing computational methods to predict MDAs.High accuracy is critical for prediction.To date,many algorithms have been proposed to infer novel MDAs.However,they may still have some drawbacks.In this paper,a logistic weighted profile-based bi-random walk method(LWBRW)is designed to infer potential MDAs based on known MDAs.In this method,three networks(i.e.,a miRNA functional similarity network,a disease semantic similarity network and a known MDA network)are constructed first.In the process of building the miRNA network and the disease network,Gaussian interaction profile(GIP)kernel is computed to increase the kernel similarities,and the logistic function is used to extract valuable information and protect known MDAs.Next,the known MDA matrix is preprocessed by the weighted K-nearest known neighbours(WKNKN)method to reduce the number of false negatives.Then,the LWBRW method is applied to infer novel MDAs by bi-randomly walking on the miRNA network and the disease network.Finally,the predictive ability of the LWBRW method is confirmed by the average AUC of 0.9393(0.0061)in 5-fold cross-validation(CV)and the AUC value of 0.9763 in leave-one-out cross-validation(LOOCV).In addition,case studies also show the outstanding ability of the LWBRW method to explore potential MDAs.
基金supported by the National Natural Science Foundation of China(No.51105229)the National Science Foundation for Distinguished Young Scholars of Hubei Province of China(No.2013CFA022)+1 种基金the Science and Technology Support Program of Hubei Province of China(N0.2015BHE026)the Fund Project of Outstanding Dissertation of China Three Gorges University(No.2014PY026)
文摘In view of the fact that the follow-up search for an optimal topology is affected by deleting a large number of high-relative-density elements. When the typical density interpolation approach, namely, solid isotropic microstructures with penalization (SIMP), is employed in the continuum structural topology optimization, a new density interpolation approach based on the logistic function is proposed in this paper. This method can weaken low-relative-density elements while enhancing high-relative-density elements by polarization, and then rationally realize polarization of the intermediate density elements. It can reduce the number of gray-scale elements as much as possible to get the optimal topology with distinct boundaries in conjunction with the sensitivity filtering method based on particle swarm optimization (PSO). Several typical numerical examples are given to demonstrate this method.
基金supported by the National Science Foundation through Grant No.CMS-0600559the American Society for Nondestructive Testing(ASNT)through the 2007 ASNT Fellowship Award.
文摘Two major challenges associated with avibration-based damage detection method using changes in natural frequencies are addressed:accurate modeling of structures and the development of a robust inverse algorithm to detect damage,which are defined as the forward and inverse problems,respectively.To resolve the forward problem,new physics-based finite element modeling techniques are developed for fillets in thin-walled beams and for bolted joints,so that complex structures can be accurately modeled with a reasonable model size.To resolve the inverse problem,a logistic function transformation is introduced to convert the constrained optimization problem to an unconstrained one,and a robust iterative algorithm using the Levenberg–Marquardt method is developed to accurately detect the locations and extent of damage.The new methodology can ensure global convergence of the iterative algorithm in solving under--determined system equations and deal with damage detection problems with relatively large modeling error and measurement noise.It is applied to various engineering structures including lightning masts,a space frame structure and one of its components,and a pipeline.The exact locations and extent of damage can be detected in the numerical simulation,and the locations and extent of damage can be successfully detected in experimental damage detection.
基金To carry out this study,the authors received a research grant(No.12-0452-596)from the Chief Scientist of Israeli Ministry of Agriculture and Rural Development。
文摘We analysed the data collected for herbaceous peony cultivated in a warm climate region and stored in winter under three constant chilling temperatures.We used the quadratic regression model to describe the stem elongation responses to winter dormancy conditions,and the logistic function to describe the weekly stems elongation.The predicted maximal stem length from the first model was used as the input parameter for the second model.More than 4000 data for various(a)chilling constant temperatures during dormancy,(b)dormancy duration,and(c)germination duration,were used.The models were applied to determine the optimal number of chill units.For this purpose,two criteria were used in different versions of the model:the maximal stem length and the maximal profit of farmers.For the two chilling temperatures of 2℃ and 6℃,the optimal values of chill units(in the models of a maximal stem length and maximal profit of farmers)are close to one another,and the values of a maximal stem length and maximal profit are significantly different.In the case of the third chilling temperature of 10℃,the model failed to determine the optimal number of chill units.The method of inverse confidence intervals for testing the significance of the optimal number of chill units was used.