Presents a waveguide CO 2 laser with two unequal long channels excited by radio frequency (RF) which has more than 30 laser lines from a long channel of 400 mm with grating, and 3 laser lines from a short channel of 2...Presents a waveguide CO 2 laser with two unequal long channels excited by radio frequency (RF) which has more than 30 laser lines from a long channel of 400 mm with grating, and 3 laser lines from a short channel of 200 mm by PZT.展开更多
With the rapid increase of large-scale problems, the distribution of real-world datasets tends to be long-tailed. Existing solutions typically involve re-balancing strategies (i.e., re-sampling and re-weighting). Alth...With the rapid increase of large-scale problems, the distribution of real-world datasets tends to be long-tailed. Existing solutions typically involve re-balancing strategies (i.e., re-sampling and re-weighting). Although they can significantly promote the classifier learning of deep networks, they will unexpectedly impair the representative ability of the learned deep features to a certain extent. Therefore, this paper proposes a dual-channel learning algorithm with involution neural networks (DC-Invo) to take care of representation learning and classifier learning concurrently. In this work, the most important thing is to combine ResNet and involution to obtain higher classification accuracy because of involution’s wider coverage in the spatial dimension. The paper conducted extensive experiments on several benchmark vision tasks including Cifar-LT, Imagenet-LT, and Places-LT, showing that DC-Invo is able to achieve significant performance gained on long-tailed datasets.展开更多
Intracellular Ca2＋ and Ca2＋-dependent signaling molecule play an essential role in the genesis of long-QT （LQT） syndrome-related ventricular arrhythmias. The effect of calcium-channel antagonist verapamil on repol...Intracellular Ca2＋ and Ca2＋-dependent signaling molecule play an essential role in the genesis of long-QT （LQT） syndrome-related ventricular arrhythmias. The effect of calcium-channel antagonist verapamil on repolarization heterogeneity of ventricular myocardium was assessed in an in vitro rabbit model of LQT syndrome. By using the monophasic action potential （MAP） recording technique, MAPs of epicardium, mid-myocardium and endocardium were simultaneously recorded by specially designed plunge-needle electrodes across the left ventricular free wall in rabbit hearts purfused by Langendorff method with standard Tyrode＇s solution. Bradycardia was induced by com- plete ablation of atrioventricular node. A catheter was introduced into the right ventricle to pace at the cycle lengths （CLs） of 1500, 1000, and 500 ms, successively. Quinidine （2 μmol/L） prolonged QT interval and ventricular MAP duration （MAPD）, and increased transmural dispersion of repolarization （TDR） in a reverse rate-dependent fashion in isolated rabbit heart. No polymorphic ventricular tachycardias were induced under this condition. The effective free therapeutic plasma concentrations of verapamil （0.01--0.05μmol/L） used in this experiment had no effect on quinidine-induced changes of QT interval, MAPD and TDR. This study demonstrated that, in this model of LQT syndrome, blockade of calcium-channel with verapmil had no effect on quinidine-induced changes of repolatiation heterogeneity of ventricular myocardium.展开更多
The successful launch and commissioning of the first geostationary meteorological satellite of Korea has the potential to enhance earth observation capability over the Asia Pacific region. Although the specifications ...The successful launch and commissioning of the first geostationary meteorological satellite of Korea has the potential to enhance earth observation capability over the Asia Pacific region. Although the specifications of the payload, the mete- orological imager （MI）, have been verified during both ground and in-orbit tests, there is the possibility of variation and/or degradation of data quality due to many different reasons, such as the accumulation of contaminants, the aging of instrument components, and unexpected external disturbance. Thus, for better utilization of MI data, it is imperative to continuously monitor and maintain the data quality. As a part of such activity, this study presents an inter-calibration, based on the Global Space-based Inter-Calibration System （GSICS）, between the MI data and the high quality hyperspectral data from the In- frared Atmospheric Sounding Interferometer （IASI） of the Metop-A satellite. Both sets of data, acquired for three years from April 2011 to March 2014, are processed to prepare the matchup dataset, which is spatially collocated, temporally concurrent, angularly coincident, and spectrally comparable. The results show that the MI data are stable within the specifications and show no significant degradation during the study period. However, the water vapor channel shows a rather large bias value of -0.77 K, with a root-mean-square difference （RMSD） of around 1.1 K, which is thought to be due to the shift in the spectral response function. The shortwave channel shows a maximum RMSD of around 1.39 K, mainly due to the coarse digitization at the lower temperature. The inter-comparison results are re-checked through a sensitivity analysis with different sets of threshold values used for the matchup dataset. Based on this, we confirm that the overall quality of the MI data meets the user requirements and maintains the expected performance, although the water vapor channel requires further investigation.展开更多
A multiple-input multiple-output interleave division multiple access (MIMO-IDMA) system with Triple Polarized Division Multiplexing (TPDM) is presented in this paper. The present methodology replaces three indepe...A multiple-input multiple-output interleave division multiple access (MIMO-IDMA) system with Triple Polarized Division Multiplexing (TPDM) is presented in this paper. The present methodology replaces three independent linearly polarized antennas with a single triple polarized antenna at both the transmitter and receiver. The users in the communication link are accommodated and separated using a user-specific interleaver combined with low rate spreading sequence. To eliminate the effects of multi-stream interference (MSI), minimum mean square error (MMSE) algorithm based on successive interference cancellation (SIC) Multi-user detection (MUD) technique is employed at the receiver. Furthermore, log-maximum a posteriori probability (MAPP) decoding algorithm is implemented at the mobile stations (MSs) to overcome the effects of multi-user interference (MUI) effects. The paper also evaluates the effects of coded MIMO-IDMA in the downlink communication by adopting the Stanford University Interim (SUI) and Long-term Evolution (LTE)channel model specifications. In comparison with the traditional uncoded system, the present solution considering turbo coded triple-polarized MIMO-IDMA system with iterative decoding algorithm provides better bit error rate (BER) with reduced signal to noise ratio (SNR). The simulation results also show that though the SNR requirement is higher for the proposed technique compared to the conventional uni-polarized antenna based MIMO-IDMA system, it gives the advantages of achieving higher data rate with reduced cost and space requirements in the context of a downlink (DL).展开更多
The selective hyperpolarization-activated cyclic nucleotide-gated（HCN） channel blocker 4-（N-ethyl-N-phenylamino）-1,2-dimethyl-6-（methylamino） pyrimidinium chloride（ZD7288） blocks the induction of long-term pot...The selective hyperpolarization-activated cyclic nucleotide-gated（HCN） channel blocker 4-（N-ethyl-N-phenylamino）-1,2-dimethyl-6-（methylamino） pyrimidinium chloride（ZD7288） blocks the induction of long-term potentiation in the perforant path-CA3 region in rat hippocampus in vivo. To explore the mechanisms underlying the action of ZD7288, we recorded excitatory postsynaptic potentials in perforant path-CA3 synapses in male Sprague-Dawley rats. We measured glutamate content in the hippocampus and in cultured hippocampal neurons using high performance liquid chromatography, and determined intracellular Ca2＋ concentration（[Ca2＋]i） using Fura-2. ZD7288 inhibited the induction and maintenance of long-term potentiation, and these effects were mirrored by the nonspecific HCN channel blocker cesium. ZD7288 also decreased glutamate release in hippocampal tissue and in cultured hippocampal neurons. Furthermore, ZD7288 attenuated glutamate-induced rises in [Ca2＋]i in a concentration-dependent manner and reversed 8-Br-c AMP-mediated facilitation of these glutamate-induced [Ca2＋]i rises. Our results suggest that ZD7288 inhibits hippocampal synaptic plasticity both glutamate release and resultant [Ca2＋]i increases in rat hippocampal neurons.展开更多
文摘Presents a waveguide CO 2 laser with two unequal long channels excited by radio frequency (RF) which has more than 30 laser lines from a long channel of 400 mm with grating, and 3 laser lines from a short channel of 200 mm by PZT.
文摘With the rapid increase of large-scale problems, the distribution of real-world datasets tends to be long-tailed. Existing solutions typically involve re-balancing strategies (i.e., re-sampling and re-weighting). Although they can significantly promote the classifier learning of deep networks, they will unexpectedly impair the representative ability of the learned deep features to a certain extent. Therefore, this paper proposes a dual-channel learning algorithm with involution neural networks (DC-Invo) to take care of representation learning and classifier learning concurrently. In this work, the most important thing is to combine ResNet and involution to obtain higher classification accuracy because of involution’s wider coverage in the spatial dimension. The paper conducted extensive experiments on several benchmark vision tasks including Cifar-LT, Imagenet-LT, and Places-LT, showing that DC-Invo is able to achieve significant performance gained on long-tailed datasets.
基金This project was supported by a grant from the National Natural Sciences Foundation of China (No 30470714)
文摘Intracellular Ca2＋ and Ca2＋-dependent signaling molecule play an essential role in the genesis of long-QT （LQT） syndrome-related ventricular arrhythmias. The effect of calcium-channel antagonist verapamil on repolarization heterogeneity of ventricular myocardium was assessed in an in vitro rabbit model of LQT syndrome. By using the monophasic action potential （MAP） recording technique, MAPs of epicardium, mid-myocardium and endocardium were simultaneously recorded by specially designed plunge-needle electrodes across the left ventricular free wall in rabbit hearts purfused by Langendorff method with standard Tyrode＇s solution. Bradycardia was induced by com- plete ablation of atrioventricular node. A catheter was introduced into the right ventricle to pace at the cycle lengths （CLs） of 1500, 1000, and 500 ms, successively. Quinidine （2 μmol/L） prolonged QT interval and ventricular MAP duration （MAPD）, and increased transmural dispersion of repolarization （TDR） in a reverse rate-dependent fashion in isolated rabbit heart. No polymorphic ventricular tachycardias were induced under this condition. The effective free therapeutic plasma concentrations of verapamil （0.01--0.05μmol/L） used in this experiment had no effect on quinidine-induced changes of QT interval, MAPD and TDR. This study demonstrated that, in this model of LQT syndrome, blockade of calcium-channel with verapmil had no effect on quinidine-induced changes of repolatiation heterogeneity of ventricular myocardium.
基金supported by the project entitled "Development of Meteorological Satellite Operation and Application Technology" of the KMA/NMSC (Korea Meteorological Adminstration/National Meteorological Satellite Center)supported by the Eco Innovation Program of KEITI (Korea Environmental Industry & Technology Institute) (Grant No. 2013000160002)
文摘The successful launch and commissioning of the first geostationary meteorological satellite of Korea has the potential to enhance earth observation capability over the Asia Pacific region. Although the specifications of the payload, the mete- orological imager （MI）, have been verified during both ground and in-orbit tests, there is the possibility of variation and/or degradation of data quality due to many different reasons, such as the accumulation of contaminants, the aging of instrument components, and unexpected external disturbance. Thus, for better utilization of MI data, it is imperative to continuously monitor and maintain the data quality. As a part of such activity, this study presents an inter-calibration, based on the Global Space-based Inter-Calibration System （GSICS）, between the MI data and the high quality hyperspectral data from the In- frared Atmospheric Sounding Interferometer （IASI） of the Metop-A satellite. Both sets of data, acquired for three years from April 2011 to March 2014, are processed to prepare the matchup dataset, which is spatially collocated, temporally concurrent, angularly coincident, and spectrally comparable. The results show that the MI data are stable within the specifications and show no significant degradation during the study period. However, the water vapor channel shows a rather large bias value of -0.77 K, with a root-mean-square difference （RMSD） of around 1.1 K, which is thought to be due to the shift in the spectral response function. The shortwave channel shows a maximum RMSD of around 1.39 K, mainly due to the coarse digitization at the lower temperature. The inter-comparison results are re-checked through a sensitivity analysis with different sets of threshold values used for the matchup dataset. Based on this, we confirm that the overall quality of the MI data meets the user requirements and maintains the expected performance, although the water vapor channel requires further investigation.
文摘A multiple-input multiple-output interleave division multiple access (MIMO-IDMA) system with Triple Polarized Division Multiplexing (TPDM) is presented in this paper. The present methodology replaces three independent linearly polarized antennas with a single triple polarized antenna at both the transmitter and receiver. The users in the communication link are accommodated and separated using a user-specific interleaver combined with low rate spreading sequence. To eliminate the effects of multi-stream interference (MSI), minimum mean square error (MMSE) algorithm based on successive interference cancellation (SIC) Multi-user detection (MUD) technique is employed at the receiver. Furthermore, log-maximum a posteriori probability (MAPP) decoding algorithm is implemented at the mobile stations (MSs) to overcome the effects of multi-user interference (MUI) effects. The paper also evaluates the effects of coded MIMO-IDMA in the downlink communication by adopting the Stanford University Interim (SUI) and Long-term Evolution (LTE)channel model specifications. In comparison with the traditional uncoded system, the present solution considering turbo coded triple-polarized MIMO-IDMA system with iterative decoding algorithm provides better bit error rate (BER) with reduced signal to noise ratio (SNR). The simulation results also show that though the SNR requirement is higher for the proposed technique compared to the conventional uni-polarized antenna based MIMO-IDMA system, it gives the advantages of achieving higher data rate with reduced cost and space requirements in the context of a downlink (DL).
基金supported by grants from the National Natural Science Foundation of China,No.81173038,81001425
文摘The selective hyperpolarization-activated cyclic nucleotide-gated（HCN） channel blocker 4-（N-ethyl-N-phenylamino）-1,2-dimethyl-6-（methylamino） pyrimidinium chloride（ZD7288） blocks the induction of long-term potentiation in the perforant path-CA3 region in rat hippocampus in vivo. To explore the mechanisms underlying the action of ZD7288, we recorded excitatory postsynaptic potentials in perforant path-CA3 synapses in male Sprague-Dawley rats. We measured glutamate content in the hippocampus and in cultured hippocampal neurons using high performance liquid chromatography, and determined intracellular Ca2＋ concentration（[Ca2＋]i） using Fura-2. ZD7288 inhibited the induction and maintenance of long-term potentiation, and these effects were mirrored by the nonspecific HCN channel blocker cesium. ZD7288 also decreased glutamate release in hippocampal tissue and in cultured hippocampal neurons. Furthermore, ZD7288 attenuated glutamate-induced rises in [Ca2＋]i in a concentration-dependent manner and reversed 8-Br-c AMP-mediated facilitation of these glutamate-induced [Ca2＋]i rises. Our results suggest that ZD7288 inhibits hippocampal synaptic plasticity both glutamate release and resultant [Ca2＋]i increases in rat hippocampal neurons.
