Long-term potentiation(LTP) of C-fiber evoked field potentials in spinal dorsal horn is first reported in 1995.Since then,the mechanisms underlying the long-lasting enhancement in synaptic transmission between primary...Long-term potentiation(LTP) of C-fiber evoked field potentials in spinal dorsal horn is first reported in 1995.Since then,the mechanisms underlying the long-lasting enhancement in synaptic transmission between primary afferent C-fibers and neurons in spinal dorsal horn have been investigated by different laboratories.In this article,the related data were summarized and discussed.展开更多
针对传统空气质量预测模型收敛速度慢,精度低的问题,提出一种基于变分模态分解(variational mode decomposition,VMD)和蜣螂优化算法(dung beetle optimizer,DBO)优化长短期记忆网络(long short term memory,LSTM)的预测模型。首先,针对...针对传统空气质量预测模型收敛速度慢,精度低的问题,提出一种基于变分模态分解(variational mode decomposition,VMD)和蜣螂优化算法(dung beetle optimizer,DBO)优化长短期记忆网络(long short term memory,LSTM)的预测模型。首先,针对AQI原始数据具有大量噪声的问题,使用VMD方法对非平稳信号进行模态分解以降低噪声对预测结果的影响从而获得多个不同特征的模态分量;其次,针对LSTM靠人工经验调参存在一定局限性,利用DBO算法对LSTM模型参数进行优化;最后,对分解后的各个子序列使用LSTM模型预测,将各个子序列进行叠加得到最后的预测结果。实验结果表明,VMD对非平稳数据的分解有助于提高预测精度,VMD-DBO-LSTM模型的性能较其他模型均有不同程度的提高,该模型预测的均方根误差为4.73μg/m^(3),平均绝对误差为3.61μg/m^(3),拟合度达到了97.8%。展开更多
singe unit discharge recordings were made from 42 WDR neurons in spinal dorsal horn in the rat. These neurons could he driven by electrical stimull activiting innocuous and noxious afferent fibres in the ipsilateral p...singe unit discharge recordings were made from 42 WDR neurons in spinal dorsal horn in the rat. These neurons could he driven by electrical stimull activiting innocuous and noxious afferent fibres in the ipsilateral plantar nerve. Traditional manual acupuncture delivered at the local acupoints Zusanli, Chengshan, Kunlun and Yongquan induced a strong inhibition or the C-fiber response. in 19 of 42 neurons obtained but did not after the A-fibre response of the neurons. The inhibition of the fibre response outlasted the period of acupuncture for more than 30 min. Neither Anor C-fibre responses in the remaining 23 neurous could be affected by manual acupuncture. These results suggest that the acupuncture stimulation specifically influences nociceptive nociceptive transmission,maybe through a presynaptic action,Furthermore, the fact that the inhibitory effect outlasts the stimulation by more than 30 min indicates that either a neuromodulatory ,presumably peptidergic action is at hand or that a temporary synaptic modification occurs in the spinal dorsal horn.展开更多
基金the National Natural Science Foundation of China(No.30200076,30370474,30570599)Department of Science and Technology of Guangdong Province,China(No.2005A30801002)
文摘Long-term potentiation(LTP) of C-fiber evoked field potentials in spinal dorsal horn is first reported in 1995.Since then,the mechanisms underlying the long-lasting enhancement in synaptic transmission between primary afferent C-fibers and neurons in spinal dorsal horn have been investigated by different laboratories.In this article,the related data were summarized and discussed.
文摘针对传统空气质量预测模型收敛速度慢,精度低的问题,提出一种基于变分模态分解(variational mode decomposition,VMD)和蜣螂优化算法(dung beetle optimizer,DBO)优化长短期记忆网络(long short term memory,LSTM)的预测模型。首先,针对AQI原始数据具有大量噪声的问题,使用VMD方法对非平稳信号进行模态分解以降低噪声对预测结果的影响从而获得多个不同特征的模态分量;其次,针对LSTM靠人工经验调参存在一定局限性,利用DBO算法对LSTM模型参数进行优化;最后,对分解后的各个子序列使用LSTM模型预测,将各个子序列进行叠加得到最后的预测结果。实验结果表明,VMD对非平稳数据的分解有助于提高预测精度,VMD-DBO-LSTM模型的性能较其他模型均有不同程度的提高,该模型预测的均方根误差为4.73μg/m^(3),平均绝对误差为3.61μg/m^(3),拟合度达到了97.8%。
文摘singe unit discharge recordings were made from 42 WDR neurons in spinal dorsal horn in the rat. These neurons could he driven by electrical stimull activiting innocuous and noxious afferent fibres in the ipsilateral plantar nerve. Traditional manual acupuncture delivered at the local acupoints Zusanli, Chengshan, Kunlun and Yongquan induced a strong inhibition or the C-fiber response. in 19 of 42 neurons obtained but did not after the A-fibre response of the neurons. The inhibition of the fibre response outlasted the period of acupuncture for more than 30 min. Neither Anor C-fibre responses in the remaining 23 neurous could be affected by manual acupuncture. These results suggest that the acupuncture stimulation specifically influences nociceptive nociceptive transmission,maybe through a presynaptic action,Furthermore, the fact that the inhibitory effect outlasts the stimulation by more than 30 min indicates that either a neuromodulatory ,presumably peptidergic action is at hand or that a temporary synaptic modification occurs in the spinal dorsal horn.
