期刊文献+
共找到132,407篇文章
< 1 2 250 >
每页显示 20 50 100
The long-term prediction of the oil-contaminated water from the Sanchi collision in the East China Sea 被引量:9
1
作者 YIN Liping ZHANG Min +1 位作者 ZHANG Yuanling QIAO Fangli 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2018年第3期69-72,共4页
The condensate and bunker oil leaked from the Sanchi collision would cause a persistent impact on marine ecosystems in the surrounding areas. The long-term prediction for the distribution of the oil-polluted water and... The condensate and bunker oil leaked from the Sanchi collision would cause a persistent impact on marine ecosystems in the surrounding areas. The long-term prediction for the distribution of the oil-polluted water and the information for the most affected regions would provide valuable information for the oceanic environment protection and pollution assessment. Based on the operational forecast system developed by the First Institute of Oceanography, State Oceanic Administration, we precisely predicted the drifting path of the oil tanker Sanchi after its collision. Trajectories of virtual oil particles show that the oil leaked from the Sanchi after it sank is mainly transported to the northeastern part of the sink location, and quickly goes to the open ocean along with the Kuroshio. Risk probability analysis based on the outcomes from the operational forecast system for years 2009 to2017 shows that the most affected area is at the northeast of the sink location. 展开更多
关键词 Sanchi collision long-term prediction oil spill
下载PDF
Long-term Prediction and Verification of Rainfall Based on the Seasonal Model
2
作者 Zheng Xiaohua Li Xingmin 《Meteorological and Environmental Research》 CAS 2014年第5期13-14,21,共3页
Using the seasonal cross-multiplication trend model, monthly precipitation of eight national basic weather stations of Shaanxi Province from 2005 to 2010 was predicted, and the forecast results were verified using the... Using the seasonal cross-multiplication trend model, monthly precipitation of eight national basic weather stations of Shaanxi Province from 2005 to 2010 was predicted, and the forecast results were verified using the rainfall scoring rules of China Meteorological Administration. The verification results show that the average score of annual precipitation prediction in recent six years is higher than that made by a professional forecaster, so this model has a good prospect of application. Moreover, the level of making prediction is steady, and it can be widely used in long-term prediction of rainfall. 展开更多
关键词 Seasonal cross-multiplication trend model long-term prediction of rainfall Forecast verification China
下载PDF
New scheme of anticipating synchronization for arbitrary anticipation time and its application to long-term prediction of chaotic states
3
作者 孙中奎 徐伟 杨晓丽 《Chinese Physics B》 SCIE EI CAS CSCD 2007年第11期3226-3230,共5页
How to predict the dynamics of nonlinear chaotic systems is still a challenging subject with important real-life applications. The present paper deals with this important yet difficult problem via a new scheme of anti... How to predict the dynamics of nonlinear chaotic systems is still a challenging subject with important real-life applications. The present paper deals with this important yet difficult problem via a new scheme of anticipating synchronization. A global, robust, analytical and delay-independent sufficient condition is obtained to guarantee the existence of anticipating synchronization manifold theoretically in the framework of the Krasovskii-Lyapunov theory. Different from 'traditional techniques (or regimes)' proposed in the previous literature, the present scheme guarantees that the receiver system can synchronize with the future state of a transmitter system for an arbitrarily long anticipation time, which allows one to predict the dynamics of chaotic transmitter at any point of time if necessary. Also it is simple to implement in practice. A classical chaotic system is employed to demonstrate the application of the proposed scheme to the long-term prediction of chaotic states. 展开更多
关键词 anticipating synchronization long-term predictability chaotic systems
下载PDF
Combination of squamous cell carcinoma antigen immunocomplex and alpha-fetoprotein in mid-and long-term prediction of hepatocellular carcinoma among cirrhotic patients 被引量:1
4
作者 Antonio Gil-Gómez Ángela Rojas +6 位作者 Chang-Hai Liu Rocio Gallego-Duran Rocio Muñoz-Hernandez Giorgio Fassina Patrizia Pontisso Javier Ampuero Manuel Romero-Gómez 《World Journal of Gastroenterology》 SCIE CAS 2021年第48期8343-8356,共14页
BACKGROUND The combination of alpha-fetoprotein(AFP)and squamous cell carcinoma antigen immunocomplex(SCCA-IgM)have been proposed for its use in the screening of hepatocellular carcinoma(HCC).Current screening program... BACKGROUND The combination of alpha-fetoprotein(AFP)and squamous cell carcinoma antigen immunocomplex(SCCA-IgM)have been proposed for its use in the screening of hepatocellular carcinoma(HCC).Current screening programs for all cirrhotic patients are controversial and a personalized screening is an unmet need in the precision medicine era.AIM To determine the role of the combination of SCCA-IgM and AFP in predicting mid-and long-term appearance of HCC.METHODS Two-hundred and three cirrhotic patients(Child A 74.9%,B 21.2%,C 3.9%)were followed-up prospectively every six months to screen HCC by ultrasound and AFP according to European Association for the Study of the Liver guidelines.The estimation cohort was recruited in Italy(30.5%;62/203)and validation cohort from Spain(69.5%;141/203).Patients underwent to evaluate SCCA-IgM by enzyme-linked immunosorbent assay(Hepa-IC,Xeptagen,Italy)and AFP levels at baseline.Patients were followed-up for 60 mo,being censored at the time of the appearance of HCC.RESULTS There were 10.8%and 23.1%of HCC development at two-and five-years followup.Patients with HCC showed higher levels of SCCA-IgM than those without it(425.72±568.33 AU/mL vs 195.93±188.40 AU/mL,P=0.009)during the fiveyear follow-up.In multivariate analysis,after adjusting by age,sex,aspartate transaminase and Child-Pugh,the following factors were independently associated with HCC:SCCA-IgM[Hazard ratio(HR)=1.001,95%CI:1.000-1.002;P=0.003],AFP(HR=1.028,95%CI:1.009-1.046;P=0.003)and creatinine(HR=1.56495%CI:1.151-2.124;P=0.004).The log-rank test of the combination resulted in 7.488(P=0.024)in estimation cohort and 11.061(P=0.004)in the validation cohort,and a 100%of correctly classified rate identifying a low-risk group in both cohorts in the two-year follow-up.CONCLUSION We have constructed a predictive model based on the combination of SCCA-IgM and AFP that provides a new HCC screening method,which could be followed by tailored HCC surveillance for individual patients,especially for those cirrhotic patients belonging to the subgroup identified as low-risk of HCC development. 展开更多
关键词 Squamous cell carcinoma antigen Hepatocellular carcinoma prediction Precision medicine Stratification of cirrhotic patient
下载PDF
Multi-scale persistent spatiotemporal transformer for long-term urban traffic flow prediction
5
作者 Jia-Jun Zhong Yong Ma +3 位作者 Xin-Zheng Niu Philippe Fournier-Viger Bing Wang Zu-kuan Wei 《Journal of Electronic Science and Technology》 EI CAS CSCD 2024年第1期53-69,共17页
Long-term urban traffic flow prediction is an important task in the field of intelligent transportation,as it can help optimize traffic management and improve travel efficiency.To improve prediction accuracy,a crucial... Long-term urban traffic flow prediction is an important task in the field of intelligent transportation,as it can help optimize traffic management and improve travel efficiency.To improve prediction accuracy,a crucial issue is how to model spatiotemporal dependency in urban traffic data.In recent years,many studies have adopted spatiotemporal neural networks to extract key information from traffic data.However,most models ignore the semantic spatial similarity between long-distance areas when mining spatial dependency.They also ignore the impact of predicted time steps on the next unpredicted time step for making long-term predictions.Moreover,these models lack a comprehensive data embedding process to represent complex spatiotemporal dependency.This paper proposes a multi-scale persistent spatiotemporal transformer(MSPSTT)model to perform accurate long-term traffic flow prediction in cities.MSPSTT adopts an encoder-decoder structure and incorporates temporal,periodic,and spatial features to fully embed urban traffic data to address these issues.The model consists of a spatiotemporal encoder and a spatiotemporal decoder,which rely on temporal,geospatial,and semantic space multi-head attention modules to dynamically extract temporal,geospatial,and semantic characteristics.The spatiotemporal decoder combines the context information provided by the encoder,integrates the predicted time step information,and is iteratively updated to learn the correlation between different time steps in the broader time range to improve the model’s accuracy for long-term prediction.Experiments on four public transportation datasets demonstrate that MSPSTT outperforms the existing models by up to 9.5%on three common metrics. 展开更多
关键词 Graph neural network Multi-head attention mechanism Spatio-temporal dependency Traffic flow prediction
下载PDF
Development of a new Cox model for predicting long-term survival in hepatitis cirrhosis patients underwent transjugular intrahepatic portosystemic shunts
6
作者 Yi-Fan Lv Bing Zhu +8 位作者 Ming-Ming Meng Yi-Fan Wu Cheng-Bin Dong Yu Zhang Bo-Wen Liu Shao-Li You Sa Lv Yong-Ping Yang Fu-Quan Liu 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第2期491-502,共12页
BACKGROUND Transjugular intrahepatic portosystemic shunt(TIPS)placement is a procedure that can effectively treat complications of portal hypertension,such as variceal bleeding and refractory ascites.However,there hav... BACKGROUND Transjugular intrahepatic portosystemic shunt(TIPS)placement is a procedure that can effectively treat complications of portal hypertension,such as variceal bleeding and refractory ascites.However,there have been no specific studies on predicting long-term survival after TIPS placement.AIM To establish a model to predict long-term survival in patients with hepatitis cirrhosis after TIPS.METHODS A retrospective analysis was conducted on a cohort of 224 patients who un-derwent TIPS implantation.Through univariate and multivariate Cox regression analyses,various factors were examined for their ability to predict survival at 6 years after TIPS.Consequently,a composite score was formulated,encompassing the indication,shunt reasonability,portal venous pressure gradient(PPG)after TIPS,percentage decrease in portal venous pressure(PVP),indocyanine green retention rate at 15 min(ICGR15)and total bilirubin(Tbil)level.Furthermore,the performance of the newly developed Cox(NDC)model was evaluated in an in-ternal validation cohort and compared with that of a series of existing models.RESULTS The indication(variceal bleeding or ascites),shunt reasonability(reasonable or unreasonable),ICGR15,post-operative PPG,percentage of PVP decrease and Tbil were found to be independent factors affecting long-term survival after TIPS placement.The NDC model incorporated these parameters and successfully identified patients at high risk,exhibiting a notably elevated mortality rate following the TIPS procedure,as observed in both the training and validation cohorts.Additionally,in terms of predicting the long-term survival rate,the performance of the NDC model was significantly better than that of the other four models[Child-Pugh,model for end-stage liver disease(MELD),MELD-sodium and the Freiburg index of post-TIPS survival].CONCLUSION The NDC model can accurately predict long-term survival after the TIPS procedure in patients with hepatitis cirrhosis,help identify high-risk patients and guide follow-up management after TIPS implantation. 展开更多
关键词 Transjugular intrahepatic portosystemic shunt long-term survival predictive model
下载PDF
Note on:“Ballistic model for the prediction of penetration depth and residual velocity in adobe:A new interpretation of the ballistic resistance of earthen masonry”
7
作者 Andreas Heine Matthias Wickert 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第1期607-609,共3页
A recently published modeling approach for the penetration into adobe and previous approaches implicitly criticized are reviewed and discussed.This article contains a note on the paper titled“Ballistic model for the ... A recently published modeling approach for the penetration into adobe and previous approaches implicitly criticized are reviewed and discussed.This article contains a note on the paper titled“Ballistic model for the prediction of penetration depth and residual velocity in adobe:A new interpretation of the ballistic resistance of earthen masonry”(DOI:https://doi.org/10.1016/j.dt.2018.07.017).Reply to the Note from Li Piani et al is linked to this article. 展开更多
关键词 ADOBE prediction earth
下载PDF
Development and validation of a model integrating clinical and coronary lesion-based functional assessment for longterm risk prediction in PCI patients
8
作者 Shao-Yu WU Rui ZHANG +5 位作者 Sheng YUAN Zhong-Xing CAI Chang-Dong GUAN Tong-Qiang ZOU Li-Hua XIE Ke-Fei DOU 《Journal of Geriatric Cardiology》 SCIE CAS CSCD 2024年第1期44-63,共20页
OBJECTIVES To establish a scoring system combining the ACEF score and the quantitative blood flow ratio(QFR) to improve the long-term risk prediction of patients undergoing percutaneous coronary intervention(PCI).METH... OBJECTIVES To establish a scoring system combining the ACEF score and the quantitative blood flow ratio(QFR) to improve the long-term risk prediction of patients undergoing percutaneous coronary intervention(PCI).METHODS In this population-based cohort study, a total of 46 features, including patient clinical and coronary lesion characteristics, were assessed for analysis through machine learning models. The ACEF-QFR scoring system was developed using 1263consecutive cases of CAD patients after PCI in PANDA Ⅲ trial database. The newly developed score was then validated on the other remaining 542 patients in the cohort.RESULTS In both the Random Forest Model and the Deep Surv Model, age, renal function(creatinine), cardiac function(LVEF)and post-PCI coronary physiological index(QFR) were identified and confirmed to be significant predictive factors for 2-year adverse cardiac events. The ACEF-QFR score was constructed based on the developmental dataset and computed as age(years)/EF(%) + 1(if creatinine ≥ 2.0 mg/d L) + 1(if post-PCI QFR ≤ 0.92). The performance of the ACEF-QFR scoring system was preliminarily evaluated in the developmental dataset, and then further explored in the validation dataset. The ACEF-QFR score showed superior discrimination(C-statistic = 0.651;95% CI: 0.611-0.691, P < 0.05 versus post-PCI physiological index and other commonly used risk scores) and excellent calibration(Hosmer–Lemeshow χ^(2)= 7.070;P = 0.529) for predicting 2-year patient-oriented composite endpoint(POCE). The good prognostic value of the ACEF-QFR score was further validated by multivariable Cox regression and Kaplan–Meier analysis(adjusted HR = 1.89;95% CI: 1.18–3.04;log-rank P < 0.01) after stratified the patients into high-risk group and low-risk group.CONCLUSIONS An improved scoring system combining clinical and coronary lesion-based functional variables(ACEF-QFR)was developed, and its ability for prognostic prediction in patients with PCI was further validated to be significantly better than the post-PCI physiological index and other commonly used risk scores. 展开更多
关键词 PATIENTS CORONARY prediction
下载PDF
Advancing Malaria Prediction in Uganda through AI and Geospatial Analysis Models
9
作者 Maria Assumpta Komugabe Richard Caballero +1 位作者 Itamar Shabtai Simon Peter Musinguzi 《Journal of Geographic Information System》 2024年第2期115-135,共21页
The resurgence of locally acquired malaria cases in the USA and the persistent global challenge of malaria transmission highlight the urgent need for research to prevent this disease. Despite significant eradication e... The resurgence of locally acquired malaria cases in the USA and the persistent global challenge of malaria transmission highlight the urgent need for research to prevent this disease. Despite significant eradication efforts, malaria remains a serious threat, particularly in regions like Africa. This study explores how integrating Gregor’s Type IV theory with Geographic Information Systems (GIS) improves our understanding of disease dynamics, especially Malaria transmission patterns in Uganda. By combining data-driven algorithms, artificial intelligence, and geospatial analysis, the research aims to determine the most reliable predictors of Malaria incident rates and assess the impact of different factors on transmission. Using diverse predictive modeling techniques including Linear Regression, K-Nearest Neighbor, Neural Network, and Random Forest, the study found that;Random Forest model outperformed the others, demonstrating superior predictive accuracy with an R<sup>2</sup> of approximately 0.88 and a Mean Squared Error (MSE) of 0.0534, Antimalarial treatment was identified as the most influential factor, with mosquito net access associated with a significant reduction in incident rates, while higher temperatures correlated with increased rates. Our study concluded that the Random Forest model was effective in predicting malaria incident rates in Uganda and highlighted the significance of climate factors and preventive measures such as mosquito nets and antimalarial drugs. We recommended that districts with malaria hotspots lacking Indoor Residual Spraying (IRS) coverage prioritize its implementation to mitigate incident rates, while those with high malaria rates in 2020 require immediate attention. By advocating for the use of appropriate predictive models, our research emphasized the importance of evidence-based decision-making in malaria control strategies, aiming to reduce transmission rates and save lives. 展开更多
关键词 MALARIA predictive Modeling Geospatial Analysis Climate Factors Preventive Measures
下载PDF
Privacy-Preserving Federated Mobility Prediction with Compound Data and Model Perturbation Mechanism
10
作者 Long Qingyue Wang Huandong +4 位作者 Chen Huiming Jin Depeng Zhu Lin Yu Li Li Yong 《China Communications》 SCIE CSCD 2024年第3期160-173,共14页
Human mobility prediction is important for many applications.However,training an accurate mobility prediction model requires a large scale of human trajectories,where privacy issues become an important problem.The ris... Human mobility prediction is important for many applications.However,training an accurate mobility prediction model requires a large scale of human trajectories,where privacy issues become an important problem.The rising federated learning provides us with a promising solution to this problem,which enables mobile devices to collaboratively learn a shared prediction model while keeping all the training data on the device,decoupling the ability to do machine learning from the need to store the data in the cloud.However,existing federated learningbased methods either do not provide privacy guarantees or have vulnerability in terms of privacy leakage.In this paper,we combine the techniques of data perturbation and model perturbation mechanisms and propose a privacy-preserving mobility prediction algorithm,where we add noise to the transmitted model and the raw data collaboratively to protect user privacy and keep the mobility prediction performance.Extensive experimental results show that our proposed method significantly outperforms the existing stateof-the-art mobility prediction method in terms of defensive performance against practical attacks while having comparable mobility prediction performance,demonstrating its effectiveness. 展开更多
关键词 federated learning mobility prediction PRIVACY
下载PDF
Two-Way Neural Network Performance PredictionModel Based onKnowledge Evolution and Individual Similarity
11
作者 Xinzheng Wang Bing Guo Yan Shen 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第2期1183-1206,共24页
Predicting students’academic achievements is an essential issue in education,which can benefit many stakeholders,for instance,students,teachers,managers,etc.Compared with online courses such asMOOCs,students’academi... Predicting students’academic achievements is an essential issue in education,which can benefit many stakeholders,for instance,students,teachers,managers,etc.Compared with online courses such asMOOCs,students’academicrelateddata in the face-to-face physical teaching environment is usually sparsity,and the sample size is relativelysmall.It makes building models to predict students’performance accurately in such an environment even morechallenging.This paper proposes a Two-WayNeuralNetwork(TWNN)model based on the bidirectional recurrentneural network and graph neural network to predict students’next semester’s course performance using only theirprevious course achievements.Extensive experiments on a real dataset show that our model performs better thanthe baselines in many indicators. 展开更多
关键词 COMPUTER EDUCATION performance prediction deep learning
下载PDF
ASLP-DL—A Novel Approach Employing Lightweight Deep Learning Framework for Optimizing Accident Severity Level Prediction
12
作者 Saba Awan Zahid Mehmood 《Computers, Materials & Continua》 SCIE EI 2024年第2期2535-2555,共21页
Highway safety researchers focus on crash injury severity,utilizing deep learning—specifically,deep neural networks(DNN),deep convolutional neural networks(D-CNN),and deep recurrent neural networks(D-RNN)—as the pre... Highway safety researchers focus on crash injury severity,utilizing deep learning—specifically,deep neural networks(DNN),deep convolutional neural networks(D-CNN),and deep recurrent neural networks(D-RNN)—as the preferred method for modeling accident severity.Deep learning’s strength lies in handling intricate relation-ships within extensive datasets,making it popular for accident severity level(ASL)prediction and classification.Despite prior success,there is a need for an efficient system recognizing ASL in diverse road conditions.To address this,we present an innovative Accident Severity Level Prediction Deep Learning(ASLP-DL)framework,incorporating DNN,D-CNN,and D-RNN models fine-tuned through iterative hyperparameter selection with Stochastic Gradient Descent.The framework optimizes hidden layers and integrates data augmentation,Gaussian noise,and dropout regularization for improved generalization.Sensitivity and factor contribution analyses identify influential predictors.Evaluated on three diverse crash record databases—NCDB 2018–2019,UK 2015–2020,and US 2016–2021—the D-RNN model excels with an ACC score of 89.0281%,a Roc Area of 0.751,an F-estimate of 0.941,and a Kappa score of 0.0629 over the NCDB dataset.The proposed framework consistently outperforms traditional methods,existing machine learning,and deep learning techniques. 展开更多
关键词 Injury SEVERITY prediction deep learning feature
下载PDF
Classifying rockburst with confidence:A novel conformal prediction approach
13
作者 Bemah Ibrahim Isaac Ahenkorah 《International Journal of Mining Science and Technology》 SCIE EI CAS CSCD 2024年第1期51-64,共14页
The scientific community recognizes the seriousness of rockbursts and the need for effective mitigation measures.The literature reports various successful applications of machine learning(ML)models for rockburst asses... The scientific community recognizes the seriousness of rockbursts and the need for effective mitigation measures.The literature reports various successful applications of machine learning(ML)models for rockburst assessment;however,a significant question remains unanswered:How reliable are these models,and at what confidence level are classifications made?Typically,ML models output single rockburst grade even in the face of intricate and out-of-distribution samples,without any associated confidence value.Given the susceptibility of ML models to errors,it becomes imperative to quantify their uncertainty to prevent consequential failures.To address this issue,we propose a conformal prediction(CP)framework built on traditional ML models(extreme gradient boosting and random forest)to generate valid classifications of rockburst while producing a measure of confidence for its output.The proposed framework guarantees marginal coverage and,in most cases,conditional coverage on the test dataset.The CP was evaluated on a rockburst case in the Sanshandao Gold Mine in China,where it achieved high coverage and efficiency at applicable confidence levels.Significantly,the CP identified several“confident”classifications from the traditional ML model as unreliable,necessitating expert verification for informed decision-making.The proposed framework improves the reliability and accuracy of rockburst assessments,with the potential to bolster user confidence. 展开更多
关键词 ROCKBURST Machine learning Uncertainty quantification Conformal prediction
下载PDF
Spatiotemporal Prediction of Urban Traffics Based on Deep GNN
14
作者 Ming Luo Huili Dou Ning Zheng 《Computers, Materials & Continua》 SCIE EI 2024年第1期265-282,共18页
Traffic prediction already plays a significant role in applications like traffic planning and urban management,but it is still difficult to capture the highly non-linear and complicated spatiotemporal correlations of ... Traffic prediction already plays a significant role in applications like traffic planning and urban management,but it is still difficult to capture the highly non-linear and complicated spatiotemporal correlations of traffic data.As well as to fulfil both long-termand short-termprediction objectives,a better representation of the temporal dependency and global spatial correlation of traffic data is needed.In order to do this,the Spatiotemporal Graph Neural Network(S-GNN)is proposed in this research as amethod for traffic prediction.The S-GNN simultaneously accepts various traffic data as inputs and investigates the non-linear correlations between the variables.In terms of modelling,the road network is initially represented as a spatiotemporal directed graph,with the features of the samples at the time step being captured by a convolution module.In order to assign varying attention weights to various adjacent area nodes of the target node,the adjacent areas information of nodes in the road network is then aggregated using a graph network.The data is output using a fully connected layer at the end.The findings show that S-GNN can improve short-and long-term traffic prediction accuracy to a greater extent;in comparison to the control model,the RMSE of S-GNN is reduced by about 0.571 to 9.288 and the MAE(Mean Absolute Error)by about 0.314 to 7.678.The experimental results on two real datasets,Pe MSD7(M)and PEMS-BAY,also support this claim. 展开更多
关键词 Urban traffic TRAFFIC temporal correlation GNN prediction
下载PDF
Prediction of treatment response to antipsychotic drugs for precision medicine approach to schizophrenia:randomized trials and multiomics analysis
15
作者 Liang-Kun Guo Yi Su +24 位作者 Yu-Ya-Nan Zhang Hao Yu Zhe Lu Wen-Qiang Li Yong-Feng Yang Xiao Xiao Hao Yan Tian-Lan Lu Jun Li Yun-Dan Liao Zhe-Wei Kang Li-Fang Wang Yue Li Ming Li Bing Liu Hai-Liang Huang Lu-Xian Lv Yin Yao Yun-Long Tan Gerome Breen Ian Everall Hong-Xing Wang Zhuo Huang Dai Zhang Wei-Hua Yue 《Military Medical Research》 SCIE CAS CSCD 2024年第1期19-33,共15页
Background:Choosing the appropriate antipsychotic drug(APD)treatment for patients with schizophrenia(SCZ)can be challenging,as the treatment response to APD is highly variable and difficult to predict due to the lack ... Background:Choosing the appropriate antipsychotic drug(APD)treatment for patients with schizophrenia(SCZ)can be challenging,as the treatment response to APD is highly variable and difficult to predict due to the lack of effective biomarkers.Previous studies have indicated the association between treatment response and genetic and epigenetic factors,but no effective biomarkers have been identified.Hence,further research is imperative to enhance precision medicine in SCZ treatment.Methods:Participants with SCZ were recruited from two randomized trials.The discovery cohort was recruited from the CAPOC trial(n=2307)involved 6 weeks of treatment and equally randomized the participants to the Olanzapine,Risperidone,Quetiapine,Aripiprazole,Ziprasidone,and Haloperidol/Perphenazine(subsequently equally assigned to one or the other)groups.The external validation cohort was recruited from the CAPEC trial(n=1379),which involved 8 weeks of treatment and equally randomized the participants to the Olanzapine,Risperidone,and Aripiprazole groups.Additionally,healthy controls(n=275)from the local community were utilized as a genetic/epigenetic reference.The genetic and epigenetic(DNA methylation)risks of SCZ were assessed using the polygenic risk score(PRS)and polymethylation score,respectively.The study also examined the genetic-epigenetic interactions with treatment response through differential methylation analysis,methylation quantitative trait loci,colocalization,and promoteranchored chromatin interaction.Machine learning was used to develop a prediction model for treatment response,which was evaluated for accuracy and clinical benefit using the area under curve(AUC)for classification,R^(2) for regression,and decision curve analysis.Results:Six risk genes for SCZ(LINC01795,DDHD2,SBNO1,KCNG2,SEMA7A,and RUFY1)involved in cortical morphology were identified as having a genetic-epigenetic interaction associated with treatment response.The developed and externally validated prediction model,which incorporated clinical information,PRS,genetic risk score(GRS),and proxy methylation level(proxyDNAm),demonstrated positive benefits for a wide range of patients receiving different APDs,regardless of sex[discovery cohort:AUC=0.874(95%CI 0.867-0.881),R^(2)=0.478;external validation cohort:AUC=0.851(95%CI 0.841-0.861),R^(2)=0.507].Conclusions:This study presents a promising precision medicine approach to evaluate treatment response,which has the potential to aid clinicians in making informed decisions about APD treatment for patients with SCZ.Trial registration Chinese Clinical Trial Registry(https://www.chictr.org.cn/),18 Aug 2009 retrospectively registered:CAPOC-ChiCTR-RNC-09000521(https://www.chictr.org.cn/showproj.aspx?proj=9014),CAPEC-ChiCTRRNC-09000522(https://www.chictr.org.cn/showproj.aspx?proj=9013). 展开更多
关键词 SCHIZOPHRENIA Antipsychotic drug Treatment response prediction model GENETICS EPIGENETICS
下载PDF
Research on the Control Strategy of Micro Wind-Hydrogen Coupled System Based on Wind Power Prediction and Hydrogen Storage System Charging/Discharging Regulation
16
作者 Yuanjun Dai Haonan Li Baohua Li 《Energy Engineering》 EI 2024年第6期1607-1636,共30页
This paper addresses the micro wind-hydrogen coupled system,aiming to improve the power tracking capability of micro wind farms,the regulation capability of hydrogen storage systems,and to mitigate the volatility of w... This paper addresses the micro wind-hydrogen coupled system,aiming to improve the power tracking capability of micro wind farms,the regulation capability of hydrogen storage systems,and to mitigate the volatility of wind power generation.A predictive control strategy for the micro wind-hydrogen coupled system is proposed based on the ultra-short-term wind power prediction,the hydrogen storage state division interval,and the daily scheduled output of wind power generation.The control strategy maximizes the power tracking capability,the regulation capability of the hydrogen storage system,and the fluctuation of the joint output of the wind-hydrogen coupled system as the objective functions,and adaptively optimizes the control coefficients of the hydrogen storage interval and the output parameters of the system by the combined sigmoid function and particle swarm algorithm(sigmoid-PSO).Compared with the real-time control strategy,the proposed predictive control strategy can significantly improve the output tracking capability of the wind-hydrogen coupling system,minimize the gap between the actual output and the predicted output,significantly enhance the regulation capability of the hydrogen storage system,and mitigate the power output fluctuation of the wind-hydrogen integrated system,which has a broad practical application prospect. 展开更多
关键词 Micro wind-hydrogen coupling system ultra-short-term wind power prediction sigmoid-PSO algorithm adaptive roll optimization predictive control strategy
下载PDF
Composition optimization and performance prediction for ultra-stable water-based aerosol based on thermodynamic entropy theory
17
作者 Tingting Kang Canjun Yan +6 位作者 Xinying Zhao Jingru Zhao Zixin Liu Chenggong Ju Xinyue Zhang Yun Zhang Yan Wu 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第3期437-446,共10页
Water-based aerosol is widely used as an effective strategy in electro-optical countermeasure on the battlefield used to the preponderance of high efficiency,low cost and eco-friendly.Unfortunately,the stability of th... Water-based aerosol is widely used as an effective strategy in electro-optical countermeasure on the battlefield used to the preponderance of high efficiency,low cost and eco-friendly.Unfortunately,the stability of the water-based aerosol is always unsatisfactory due to the rapid evaporation and sedimentation of the aerosol droplets.Great efforts have been devoted to improve the stability of water-based aerosol by using additives with different composition and proportion.However,the lack of the criterion and principle for screening the effective additives results in excessive experimental time consumption and cost.And the stabilization time of the aerosol is still only 30 min,which could not meet the requirements of the perdurable interference.Herein,to improve the stability of water-based aerosol and optimize the complex formulation efficiently,a theoretical calculation method based on thermodynamic entropy theory is proposed.All the factors that influence the shielding effect,including polyol,stabilizer,propellant,water and cosolvent,are considered within calculation.An ultra-stable water-based aerosol with long duration over 120 min is obtained with the optimal fogging agent composition,providing enough time for fighting the electro-optic weapon.Theoretical design guideline for choosing the additives with high phase transition temperature and low phase transition enthalpy is also proposed,which greatly improves the total entropy change and reduce the absolute entropy change of the aerosol cooling process,and gives rise to an enhanced stability of the water-based aerosol.The theoretical calculation methodology contributes to an abstemious time and space for sieving the water-based aerosol with desirable performance and stability,and provides the powerful guarantee to the homeland security. 展开更多
关键词 Ultra-stable Water-based aerosol Thermodynamic entropy Composition optimization Performance prediction
下载PDF
Continuous-Time Channel Prediction Based on Tensor Neural Ordinary Differential Equation
18
作者 Mingyao Cui Hao Jiang +2 位作者 Yuhao Chen Yang Du Linglong Dai 《China Communications》 SCIE CSCD 2024年第1期163-174,共12页
Channel prediction is critical to address the channel aging issue in mobile scenarios.Existing channel prediction techniques are mainly designed for discrete channel prediction,which can only predict the future channe... Channel prediction is critical to address the channel aging issue in mobile scenarios.Existing channel prediction techniques are mainly designed for discrete channel prediction,which can only predict the future channel in a fixed time slot per frame,while the other intra-frame channels are usually recovered by interpolation.However,these approaches suffer from a serious interpolation loss,especially for mobile millimeter-wave communications.To solve this challenging problem,we propose a tensor neural ordinary differential equation(TN-ODE)based continuous-time channel prediction scheme to realize the direct prediction of intra-frame channels.Specifically,inspired by the recently developed continuous mapping model named neural ODE in the field of machine learning,we first utilize the neural ODE model to predict future continuous-time channels.To improve the channel prediction accuracy and reduce computational complexity,we then propose the TN-ODE scheme to learn the structural characteristics of the high-dimensional channel by low-dimensional learnable transform.Simulation results show that the proposed scheme is able to achieve higher intra-frame channel prediction accuracy than existing schemes. 展开更多
关键词 channel prediction massive multipleinput-multiple-output millimeter-wave communications ordinary differential equation
下载PDF
An Initial Perturbation Method for the Multiscale Singular Vector in Global Ensemble Prediction
19
作者 Xin LIU Jing CHEN +6 位作者 Yongzhu LIU Zhenhua HUO Zhizhen XU Fajing CHEN Jing WANG Yanan MA Yumeng HAN 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第3期545-563,共19页
Ensemble prediction is widely used to represent the uncertainty of single deterministic Numerical Weather Prediction(NWP) caused by errors in initial conditions(ICs). The traditional Singular Vector(SV) initial pertur... Ensemble prediction is widely used to represent the uncertainty of single deterministic Numerical Weather Prediction(NWP) caused by errors in initial conditions(ICs). The traditional Singular Vector(SV) initial perturbation method tends only to capture synoptic scale initial uncertainty rather than mesoscale uncertainty in global ensemble prediction. To address this issue, a multiscale SV initial perturbation method based on the China Meteorological Administration Global Ensemble Prediction System(CMA-GEPS) is proposed to quantify multiscale initial uncertainty. The multiscale SV initial perturbation approach entails calculating multiscale SVs at different resolutions with multiple linearized physical processes to capture fast-growing perturbations from mesoscale to synoptic scale in target areas and combining these SVs by using a Gaussian sampling method with amplitude coefficients to generate initial perturbations. Following that, the energy norm,energy spectrum, and structure of multiscale SVs and their impact on GEPS are analyzed based on a batch experiment in different seasons. The results show that the multiscale SV initial perturbations can possess more energy and capture more mesoscale uncertainties than the traditional single-SV method. Meanwhile, multiscale SV initial perturbations can reflect the strongest dynamical instability in target areas. Their performances in global ensemble prediction when compared to single-scale SVs are shown to(i) improve the relationship between the ensemble spread and the root-mean-square error and(ii) provide a better probability forecast skill for atmospheric circulation during the late forecast period and for short-to medium-range precipitation. This study provides scientific evidence and application foundations for the design and development of a multiscale SV initial perturbation method for the GEPS. 展开更多
关键词 multiscale uncertainty singular vector initial perturbation global ensemble prediction system
下载PDF
Uniaxial Compressive Strength Prediction for Rock Material in Deep Mine Using Boosting-Based Machine Learning Methods and Optimization Algorithms
20
作者 Junjie Zhao Diyuan Li +1 位作者 Jingtai Jiang Pingkuang Luo 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第7期275-304,共30页
Traditional laboratory tests for measuring rock uniaxial compressive strength(UCS)are tedious and timeconsuming.There is a pressing need for more effective methods to determine rock UCS,especially in deep mining envir... Traditional laboratory tests for measuring rock uniaxial compressive strength(UCS)are tedious and timeconsuming.There is a pressing need for more effective methods to determine rock UCS,especially in deep mining environments under high in-situ stress.Thus,this study aims to develop an advanced model for predicting the UCS of rockmaterial in deepmining environments by combining three boosting-basedmachine learning methods with four optimization algorithms.For this purpose,the Lead-Zinc mine in Southwest China is considered as the case study.Rock density,P-wave velocity,and point load strength index are used as input variables,and UCS is regarded as the output.Subsequently,twelve hybrid predictive models are obtained.Root mean square error(RMSE),mean absolute error(MAE),coefficient of determination(R2),and the proportion of the mean absolute percentage error less than 20%(A-20)are selected as the evaluation metrics.Experimental results showed that the hybridmodel consisting of the extreme gradient boostingmethod and the artificial bee colony algorithm(XGBoost-ABC)achieved satisfactory results on the training dataset and exhibited the best generalization performance on the testing dataset.The values of R2,A-20,RMSE,and MAE on the training dataset are 0.98,1.0,3.11 MPa,and 2.23MPa,respectively.The highest values of R2 and A-20(0.93 and 0.96),and the smallest RMSE and MAE values of 4.78 MPa and 3.76MPa,are observed on the testing dataset.The proposed hybrid model can be considered a reliable and effective method for predicting rock UCS in deep mines. 展开更多
关键词 Uniaxial compression strength strength prediction machine learning optimization algorithm
下载PDF
上一页 1 2 250 下一页 到第
使用帮助 返回顶部