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高频rTMS联合安宫牛黄丸治疗脓毒症相关性脑病的临床研究
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作者 刘超 叶伦河 高林 《中文科技期刊数据库(引文版)医药卫生》 2024年第7期0031-0034,共4页
对予以脓毒症相关性脑病患者高频rTMS联合安宫牛黄丸治疗的效果展开分析和探讨。方法 在研究中纳入2023年7月至2024年12月期间在我院综合ICU接受治疗的SAE患者60例,以随机数 字表法为依据对所有患者行分两组处理,除常规综合治疗外,为对... 对予以脓毒症相关性脑病患者高频rTMS联合安宫牛黄丸治疗的效果展开分析和探讨。方法 在研究中纳入2023年7月至2024年12月期间在我院综合ICU接受治疗的SAE患者60例,以随机数 字表法为依据对所有患者行分两组处理,除常规综合治疗外,为对照组患者实施安宫牛黄丸治疗方案,为观察组患者实施高频rTMS联合安宫牛黄丸治疗方案,观察两组患者治疗结局。结果 治疗后观察组患者的MoCA、GCS评分明显高于对照组患者;经治疗两组患者包括S-100β、NSE、NT-proCNP在内的脑损伤指标水平均较治疗前有所下降,其中观察组下降幅度较对照组患者更大;治疗后观察组患者包括IL-6、PCT、TNF-α在内的炎症因子指标水平均明显低于对照组患者(P<0.05)。结论 为脓毒血症相关性脑病患者实施高频rTMS联合安宫牛黄丸治疗能使之认知功能、意识状态得到更好改善,帮助患者减轻脑损伤与机体炎症反应,对其疾病预后更为有利。 展开更多
关键词 高频rtms 安宫牛黄丸 脓毒症相关性脑病 临床疗效
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rTMS辅助帕利哌酮治疗精神分裂症合并强迫症的效果及对血清PRL、HCY水平的影响
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作者 丁毓颖 黄焱 +7 位作者 陆怡 王国元 彭四新 谢清芳 朱宏伟 王能焜 曹彧 徐伟珍 《贵州医药》 CAS 2024年第4期537-539,共3页
目的 观察重复经颅磁刺激(rTMS)辅助帕利哌酮治疗精神分裂症合并强迫症的临床疗效及对患者血清中PRL、HCY水平的影响。方法 将116例于我院住院治疗的精神分裂症患者随机分为对照组(帕利哌酮缓释片)和观察组(帕利哌酮缓释片+高频率rTMS),... 目的 观察重复经颅磁刺激(rTMS)辅助帕利哌酮治疗精神分裂症合并强迫症的临床疗效及对患者血清中PRL、HCY水平的影响。方法 将116例于我院住院治疗的精神分裂症患者随机分为对照组(帕利哌酮缓释片)和观察组(帕利哌酮缓释片+高频率rTMS),各58例,共治疗4周。比较两组患者临床疗效、阳性症状、阴性症状及一般精神病理症状、Y-BOCS评分、泌乳素(PRL)及同型半胱氨酸(HCY)水平及不良反应。结果 治疗后,观察组的总有效率高于对照组,差异有统计学意义(P<0.05)。观察组阳性症状、阴性症状及一般精神病理症状评分、Y-BOCS评分均显著低于对照组,差异均有统计学意义(P<0.05)。观察组PRL及HCY水平低于对照组,差异均有统计学意义(P<0.05)。治疗期间,两组患者不良反应发生率差异无统计学意义(P>0.05)。结论 rTMS辅助帕利哌酮治疗精神分裂症合并强迫症具有良好的疗效,可显著改善患者的认知功能障碍及强迫症状,降低PRL水平,且安全性高。 展开更多
关键词 rtms 帕利哌酮 精神分裂症 强迫症 PRL HCY
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双侧序贯rTMS联合米氮平治疗首发重度抑郁症的效果及对5-HT、DA、NE、睡眠质量的影响
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作者 黄百花 刘翔 谢根英 《中国医学创新》 CAS 2024年第10期6-10,共5页
目的:研究双侧序贯重复经颅磁刺激(rTMS)联合米氮平治疗首发重度抑郁症(MDD)的效果及对5-羟色胺(5-HT)、多巴胺(DA)、去甲肾上腺素(NE)、睡眠质量的影响。方法:选取2022年1月—2023年6月吉安市第三人民医院诊治的120例患者符合首发MDD... 目的:研究双侧序贯重复经颅磁刺激(rTMS)联合米氮平治疗首发重度抑郁症(MDD)的效果及对5-羟色胺(5-HT)、多巴胺(DA)、去甲肾上腺素(NE)、睡眠质量的影响。方法:选取2022年1月—2023年6月吉安市第三人民医院诊治的120例患者符合首发MDD诊断的临床患者为研究对象,随机将其分为三组,各40例,分别为对照一组、对照二组及研究组,三组均予以米氮平治疗,对照二组给予左侧10 Hz rTMS治疗,研究组给予双侧10 Hz+1 Hz序贯rTMS治疗,均持续治疗4周。比较三组治疗前、治疗2、4周后抑郁程度[汉密尔顿抑郁量表(HAMD-17)]、睡眠质量[匹兹堡睡眠质量指数(PSQI)]、临床疗效及不良反应发生率[不良反应量表(TESS)],记录治疗前后血清5-HT、DA及NE水平变化。结果:治疗2、4周后,三组HAMD-17评分均下降,且研究组的HAMD-17评分均低于对照一组、对照二组,对照二组HAMD-17评分均低于对照一组,差异均有统计学意义(P<0.05)。治疗2、4周后,三组PSQI评分均下降,且研究组的PSQI评分均低于对照一组、对照二组,对照二组PSQI评分均低于对照一组,差异均有统计学意义(P<0.05)。研究组的临床总有效率为90.00%,高于对照二组的72.50%与对照一组的60.00%,差异均有统计学意义(P<0.05)。治疗后,三组血清5-HT、NE及DA水平均上升,且研究组血清5-HT及DA水平均高于对照一组、对照二组,NE水平低于对照一组、对照二组,对照二组5-HT、NE及DA水平均高于对照一组,NE水平低于对照一组,差异均有统计学意义(P<0.05)。三组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:与单纯米氮平治疗及药物联合单侧rTMS治疗相比,双侧序贯rTMS联合药物治疗首发MDD患者效果确切,可有效改善患者睡眠质量及抑郁症状,促进神经递质代谢,安全性好。 展开更多
关键词 双侧序贯rtms 米氮平 首发重度抑郁症 神经递质 睡眠质量
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血府逐瘀丸联合rTMS对围绝经期偏头痛患者的临床疗效
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作者 王玉 易茗 +2 位作者 张涵妮 肖长江 王青 《中成药》 CAS CSCD 北大核心 2024年第9期2967-2971,共5页
目的探讨血府逐瘀丸联合重复经颅磁刺激(rTMS)对围绝经期偏头痛患者的临床疗效。方法90例患者随机分为对照组和观察组,每组45例,对照组给予rTMS,观察组在对照组基础上加用血府逐瘀丸。检测临床疗效、头痛症状评分、血液流变学指标(高切... 目的探讨血府逐瘀丸联合重复经颅磁刺激(rTMS)对围绝经期偏头痛患者的临床疗效。方法90例患者随机分为对照组和观察组,每组45例,对照组给予rTMS,观察组在对照组基础上加用血府逐瘀丸。检测临床疗效、头痛症状评分、血液流变学指标(高切全血黏度、低切全血黏度、血浆黏度、纤维蛋白原)、炎性因子(IL-6、IL-10、TNF-α、CGRP)、AIS评分、CD-RISC评分、MSQ评分、不良反应发生率变化。结果观察组总有效率高于对照组(P<0.05)。治疗后,2组头痛症状评分、血液流变学指标、IL-6、TNF-α、CGRP、AIS评分、MSQ评分降低(P<0.05),IL-10、CD-RISC评分升高(P<0.05)。2组不良反应发生率比较,差异无统计学意义(P>0.05)。结论血府逐瘀丸联合rTMS可安全有效地缓解围绝经期偏头痛患者临床症状。 展开更多
关键词 血府逐瘀丸 重复经颅磁刺激(rtms) 围绝经期 偏头痛
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高频rTMS改善酒精依赖患者睡眠与抑郁障碍的效果
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作者 陈称美 朱可洲 +3 位作者 王琳 彭小慧 谢贤炜 王晓丽 《中国医学创新》 CAS 2024年第4期45-49,共5页
目的:探讨高频重复经颅磁刺激(repetitive transcranial magnetic stimulation,rTMS)改善酒精依赖患者睡眠与抑郁障碍的效果。方法:选取2022年8月—2023年2月赣州市第三人民医院收治的酒精依赖患者80例为研究对象,按照随机数字表法分为... 目的:探讨高频重复经颅磁刺激(repetitive transcranial magnetic stimulation,rTMS)改善酒精依赖患者睡眠与抑郁障碍的效果。方法:选取2022年8月—2023年2月赣州市第三人民医院收治的酒精依赖患者80例为研究对象,按照随机数字表法分为两组,每组40例。对照组进行伪刺激治疗,观察组采用高频rTMS治疗,两组均维持治疗4周。对比两组治疗前、治疗4周后的失眠严重程度指数(insomnia severity index,ISI)、匹兹堡睡眠质量指数(Pittsburgh sleep quality index,PSQI)、抑郁自评量表(self-rating depression scale,SDS)、焦虑自评量表(self-rating anxiety scale,SAS)评分及神经递质水平。结果:治疗前,两组ISI、PSQI各项评分及总分、SDS评分、SAS评分、多巴胺(dopamine,DA)水平、5-羟色胺(5-hydroxytryptamine,5-HT)水平比较,差异均无统计学意义(P>0.05);治疗4周后,观察组的日间功能障碍[(1.01±0.11)分]、睡眠障碍[(0.84±0.39)分]、入睡时间[(0.96±0.17)分]、睡眠效率[(1.01±0.15)分]、睡眠时间[(0.71±0.28)分]、睡眠质量[(0.87±0.24)分]、催眠药物[(0.73±0.22)分]及总分[(6.13±0.51)分]、ISI[(5.17±2.12)分]、SDS[(39.27±7.15)分]、SAS[(32.15±6.33)分]、DA[(71.32±4.35)ng/L]均低于对照组[(1.53±0.21)分、(1.34±0.60)分、(1.65±0.36)分、(1.44±0.32)分、(1.30±0.35)分、(1.53±0.31)分、(1.30±0.34)分、(10.09±0.82)分、(8.36±4.09)分、(47.22±8.56)分、(43.05±7.96)分、(87.88±5.62)ng/L],观察组的5-HT[(269.72±27.04)ng/mL]高于对照组[(197.33±25.88)ng/mL],差异均有统计学意义(P<0.05)。结论:高频rTMS治疗能够明显改善酒精依赖患者的睡眠质量,有效缓解患者负面情绪,进一步提升患者神经功能。 展开更多
关键词 酒精依赖 高频rtms 睡眠障碍 抑郁障碍 失眠 焦虑
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Enhancing Low-Frequency Microwave Absorption Through Structural Polarization Modulation of MXenes
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作者 Bo Shan Yang Wang +1 位作者 Xinyi Ji Yi Huang 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第10期435-452,共18页
Two-dimensional carbon-based materials have shown promising electromagnetic wave absorption capabilities in mid-and high-frequency ranges,but face challenges in low-frequency absorption due to limited control over pol... Two-dimensional carbon-based materials have shown promising electromagnetic wave absorption capabilities in mid-and high-frequency ranges,but face challenges in low-frequency absorption due to limited control over polarization response mecha-nisms and ambiguous resonance behavior.In this study,we pro-pose a novel approach to enhance absorption efficiency in aligned three-dimensional(3D)MXene/CNF(cellulose nanofibers)cavities by modifying polarization properties and manipulating resonance response in the 3D MXene architecture.This controlled polarization mechanism results in a significant shift of the main absorption region from the X-band to the S-band,leading to a remarkable reflection loss value of-47.9 dB in the low-frequency range.Furthermore,our findings revealed the importance of the oriented electromagnetic coupling in influencing electromagnetic response and microwave absorption properties.The present study inspired us to develop a generic strategy for low-frequency tuned absorption in the absence of magnetic element participation,while orientation-induced polarization and the derived magnetic resonance coupling are the key controlling factors of the method. 展开更多
关键词 Hierarchical structure MXene Microwave absorption low-frequency
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Low-frequency oscillation of train-network system considering traction power supply mode
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作者 Yuchen Liu Xiaoqin Lyu +1 位作者 Mingyuan Chang Qiqi Yang 《Railway Engineering Science》 EI 2024年第2期244-256,共13页
The low-frequency oscillation(LFO)has occurred in the train-network system due to the introduction of the power electronics of the trains.The modeling and analyzing method in current researches based on electrified ra... The low-frequency oscillation(LFO)has occurred in the train-network system due to the introduction of the power electronics of the trains.The modeling and analyzing method in current researches based on electrified railway unilateral power supply system are not suitable for the LFO analysis in a bilateral power supply system,where the trains are supplied by two traction substations.In this work,based on the single-input and single-output impedance model of China CRH5 trains,the node admittance matrices of the train-network system both in unilateral and bilateral power supply modes are established,including three-phase power grid,traction transformers and traction network.Then the modal analysis is used to study the oscillation modes and propagation characteristics of the unilateral and bilateral power supply systems.Moreover,the influence of the equivalent inductance of the power grid,the length of the transmission line,and the length of the traction network are analyzed on the critical oscillation mode of the bilateral power supply system.Finally,the theoretical analysis results are verified by the time-domain simulation model in MATLAB/Simulink. 展开更多
关键词 low-frequency oscillation Train-network system Modal analysis Bilateral power supply Participation factor
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A seismic elastic moduli module for the measurements of low-frequency wave dispersion and attenuation of fluid-saturated rocks under different pressures
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作者 Yan-Xiao He Shang-Xu Wang +9 位作者 Gen-Yang Tang Chao Sun Hong-Bing Li San-Yi Yuan Xian Wei Li-Deng Gan Xiao-Feng Dai Qiang Ge Peng-Peng Wei Hui-Qing Zhang 《Petroleum Science》 SCIE EI CAS CSCD 2024年第1期162-181,共20页
Knowledge about the seismic elastic modulus dispersion,and associated attenuation,in fluid-saturated rocks is essential for better interpretation of seismic observations taken as part of hydrocarbon identification and... Knowledge about the seismic elastic modulus dispersion,and associated attenuation,in fluid-saturated rocks is essential for better interpretation of seismic observations taken as part of hydrocarbon identification and time-lapse seismic surveillance of both conventional and unconventional reservoir and overburden performances.A Seismic Elastic Moduli Module has been developed,based on the forced-oscillations method,to experimentally investigate the frequency dependence of Young's modulus and Poisson's ratio,as well as the inferred attenuation,of cylindrical samples under different confining pressure conditions.Calibration with three standard samples showed that the measured elastic moduli were consistent with the published data,indicating that the new apparatus can operate reliably over a wide frequency range of f∈[1-2000,10^(6)]Hz.The Young's modulus and Poisson's ratio of the shale and the tight sandstone samples were measured under axial stress oscillations to assess the frequency-and pressure-dependent effects.Under dry condition,both samples appear to be nearly frequency independent,with weak pressure dependence for the shale and significant pressure dependence for the sandstone.In particular,it was found that the tight sandstone with complex pore microstructure exhibited apparent dispersion and attenuation under brine or glycerin saturation conditions,the levels of which were strongly influenced by the increased effective pressure.In addition,the measured Young's moduli results were compared with the theoretical predictions from a scaled poroelastic model with a reasonably good agreement,revealing that the combined fluid flow mechanisms at both mesoscopic and microscopic scales possibly responsible for the measured dispersion. 展开更多
关键词 low-frequency measurements Dispersion and attenuation Rock physics Fluid flow
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Suppression of low-frequency ultrasound broadband vibration using star-shaped single-phase metamaterials
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作者 Rui Zhao Jian Zheng +4 位作者 Jin Guo Yunbo Shi Hengzhen Feng Jun Tang Jun Liu 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第4期217-224,共8页
In order to suppress the low-frequency ultrasound vibration in the broadband range of 20 k Hz—100 k Hz,this paper proposes and discusses an acoustic metamaterial with low-frequency ultrasound vibration attenuation pr... In order to suppress the low-frequency ultrasound vibration in the broadband range of 20 k Hz—100 k Hz,this paper proposes and discusses an acoustic metamaterial with low-frequency ultrasound vibration attenuation properties,which is configured by hybrid arc and sharp-angle convergent star-shaped lattices.The effect of the dispersion relation and the bandgap characteristic for the scatterers in star-shaped are simulated and analyzed.The target bandgap width is extended by optimizing the geometry parameters of arc and sharp-angle convergent lattices.The proposed metamaterial configured by optimized hybrid lattices exhibits remarkable broad bandgap characteristics by bandgap complementarity,and the simulation results verify a 99%vibration attenuation amplitude can be obtained in the frequency of20 k Hz—100 k Hz.After the fabrication of the proposed hybrid configurational star-shaped metamaterial by 3D printing technique,the transmission loss experiments are performed,and the experimental results indicate that the fabricated metamaterial has the characteristics of broadband vibration attenuation and an amplitude greater than 85%attenuation for the target frequency.These results demonstrate that the hybrid configurational star-shaped metamaterials can effectively widen the bandgap and realize high efficiency attenuation,which has capability for the vibration attenuation in the application of highprecise equipment. 展开更多
关键词 Star-shaped metamaterials BROADBAND Vibration attenuation low-frequency ultrasound vibration Transmission loss
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Current optimization-based control of dual three-phase PMSM for low-frequency temperature swing reduction
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作者 Linlin Lu Xueqing Wang +3 位作者 Luhan Jin Qiong Liu Yun Zhang Yao Mao 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第4期238-246,共9页
In this paper,a control scheme based on current optimization is proposed for dual three-phase permanent-magnet synchronous motor(DTP-PMSM)drive to reduce the low-frequency temperature swing.The reduction of temperatur... In this paper,a control scheme based on current optimization is proposed for dual three-phase permanent-magnet synchronous motor(DTP-PMSM)drive to reduce the low-frequency temperature swing.The reduction of temperature swing can be equivalent to reducing maximum instantaneous phase copper loss in this paper.First,a two-level optimization aiming at minimizing maximum instantaneous phase copper loss at each electrical angle is proposed.Then,the optimization is transformed to a singlelevel optimization by introducing the auxiliary variable for easy solving.Considering that singleobjective optimization trades a great total copper loss for a small reduction of maximum phase copper loss,the optimization considering both instantaneous total copper loss and maximum phase copper loss is proposed,which has the same performance of temperature swing reduction but with lower total loss.In this way,the proposed control scheme can reduce maximum junction temperature by 11%.Both simulation and experimental results are presented to prove the effectiveness and superiority of the proposed control scheme for low-frequency temperature swing reduction. 展开更多
关键词 Dual three-phase PMSM low-frequency temperature swing Copper loss Current optimization Connected neutral points
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High-order Bragg forward scattering and frequency shift of low-frequency underwater acoustic field by moving rough sea surface
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作者 莫亚枭 张朝金 +2 位作者 鹿力成 孙启航 马力 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第3期459-470,共12页
Acoustic scattering modulation caused by an undulating sea surface on the space-time dimension seriously affects underwater detection and target recognition.Herein,underwater acoustic scattering modulation from a movi... Acoustic scattering modulation caused by an undulating sea surface on the space-time dimension seriously affects underwater detection and target recognition.Herein,underwater acoustic scattering modulation from a moving rough sea surface is studied based on integral equation and parabolic equation.And with the principles of grating and constructive interference,the mechanism of this acoustic scattering modulation is explained.The periodicity of the interference of moving rough sea surface will lead to the interference of the scattering field at a series of discrete angles,which will form comb-like and frequency-shift characteristics on the intensity and the frequency spectrum of the acoustic scattering field,respectively,which is a high-order Bragg scattering phenomenon.Unlike the conventional Doppler effect,the frequency shifts of the Bragg scattering phenomenon are multiples of the undulating sea surface frequency and are independent of the incident sound wave frequency.Therefore,even if a low-frequency underwater acoustic field is incident,it will produce obvious frequency shifts.Moreover,under the action of ideal sinusoidal waves,swells,fully grown wind waves,unsteady wind waves,or mixed waves,different moving rough sea surfaces create different acoustic scattering processes and possess different frequency shift characteristics.For the swell wave,which tends to be a single harmonic wave,the moving rough sea surface produces more obvious high-order scattering and frequency shifts.The same phenomena are observed on the sea surface under fully grown wind waves,however,the frequency shift slightly offsets the multiple peak frequencies of the wind wave spectrum.Comparing with the swell and fully-grown wind waves,the acoustic scattering and frequency shift are not obvious for the sea surface under unsteady wind waves. 展开更多
关键词 high-order Bragg scattering frequency shift low-frequency acoustic field moving rough sea surface
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A low-frequency pure metal metamaterial absorber with continuously tunable stiffness
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作者 Xingzhong WANG Shiteng RUI +2 位作者 Shaokun YANG Weiquan ZHANG Fuyin MA 《Applied Mathematics and Mechanics(English Edition)》 SCIE EI CSCD 2024年第7期1209-1224,共16页
To address the incompatibility between high environmental adaptability and deep subwavelength characteristics in conventional local resonance metamaterials,and overcome the deficiencies in the stability of existing ac... To address the incompatibility between high environmental adaptability and deep subwavelength characteristics in conventional local resonance metamaterials,and overcome the deficiencies in the stability of existing active control techniques for band gaps,this paper proposes a design method of pure metal vibration damping metamaterial with continuously tunable stiffness for wideband elastic wave absorption.We design a dual-helix narrow-slit pure metal metamaterial unit,which possesses the triple advantage of high spatial compactness,low stiffness characteristics,and high structural stability,enabling the opening of elastic flexural band gaps in the low-frequency range.Similar to the principle of a sliding rheostat,the introduction of continuously sliding plug-ins into the helical slits enables the continuous variation of the stiffness of the metamaterial unit,achieving a continuously tunable band gap effect.This successfully extends the effective band gap by more than ten times.The experimental results indicate that this metamaterial unit can be used as an additional vibration absorber to absorb the low-frequency vibration energy effectively.Furthermore,it advances the metamaterial absorbers from a purely passive narrowband design to a wideband tunable one.The pure metal double-helix metamaterials retain the subwavelength properties of metamaterials and are suitable for deployment in harsh environments.Simultaneously,by adjusting its stiffness,it substantially broadens the effective band gap range,presenting promising potential applications in various mechanical equipment operating under adverse conditions. 展开更多
关键词 elastic metamaterial absorber continuously tunable stiffness low-frequency vibration damping variable stiffness design pure metal structure
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Diagnosing ratio of electron density to collision frequency of plasma surrounding scaled model in a shock tube using low-frequency alternating magnetic field phase shift
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作者 吴明兴 谢楷 +3 位作者 刘艳 徐晗 张宝 田得阳 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第5期519-530,共12页
A non-contact low-frequency(LF)method of diagnosing the plasma surrounding a scaled model in a shock tube is proposed.This method utilizes the phase shift occurring after the transmission of an LF alternating magnetic... A non-contact low-frequency(LF)method of diagnosing the plasma surrounding a scaled model in a shock tube is proposed.This method utilizes the phase shift occurring after the transmission of an LF alternating magnetic field through the plasma to directly measure the ratio of the plasma loop average electron density to collision frequency.An equivalent circuit model is used to analyze the relationship of the phase shift of the magnetic field component of LF electromagnetic waves with the plasma electron density and collision frequency.The applicable range of the LF method on a given plasma scale is analyzed.The upper diagnostic limit for the ratio of the electron density(unit:m^(-3))to collision frequency(unit:Hz)exceeds 1×10^(11),enabling an electron density to exceed 1×10^(20)m^(-3)and a collision frequency to be less than 1 GHz.In this work,the feasibility of using the LF phase shift to implement the plasma diagnosis is also assessed.Diagnosis experiments on shock tube equipment are conducted by using both the electrostatic probe method and LF method.By comparing the diagnostic results of the two methods,the inversion results are relatively consistent with each other,thereby preliminarily verifying the feasibility of the LF method.The ratio of the electron density to the collision frequency has a relatively uniform distribution during the plasma stabilization.The LF diagnostic path is a loop around the model,which is suitable for diagnosing the plasma that surrounds the model.Finally,the causes of diagnostic discrepancy between the two methods are analyzed.The proposed method provides a new avenue for diagnosing high-density enveloping plasma. 展开更多
关键词 low-frequency alternating magnetic field phase shift shock-tube plasma diagnosis electron density collision frequency
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清心定志汤联合高频rTMS治疗精神分裂症疗效观察及对脑神经营养因子的影响
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作者 徐家庭 兰智勇 +1 位作者 叶露雯 勾东方 《新中医》 CAS 2024年第18期55-59,共5页
目的:观察清心定志汤联合高频经颅磁刺激(rTMS)治疗精神分裂症(SP)的临床疗效及对脑神经营养因子水平的影响。方法:选取106例SP患者为研究对象,以随机数字表法分为试验组与对照组各53例。2组均给予基础治疗,对照组加用高频rTMS治疗,试... 目的:观察清心定志汤联合高频经颅磁刺激(rTMS)治疗精神分裂症(SP)的临床疗效及对脑神经营养因子水平的影响。方法:选取106例SP患者为研究对象,以随机数字表法分为试验组与对照组各53例。2组均给予基础治疗,对照组加用高频rTMS治疗,试验组在对照组基础上加用清心定志汤治疗,2组均治疗4周。比较2组临床疗效、中医证候评分、阳性与阴性综合征量表(PANSS)评分、阴性症状量表(SANS)评分及脑神经营养因子[脑源性神经营养因子(BDNF)、胶质原性神经营养因子(GDNF)]水平。结果:试验组总有效率为94.34%,对照组为77.36%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组中医证候评分均较治疗前降低(P<0.05),且试验组中医证候评分低于对照组(P<0.05)。治疗后,2组PANSS、SANS评分均较治疗前降低(P<0.05),且试验组PANSS、SANS评分均低于对照组(P<0.05)。治疗后,2组血清BDNF、GDNF水平均较治疗前升高(P<0.05),且试验组BDNF、GDNF水平均高于对照组(P<0.05)。结论:清心定志汤联合高频rTMS治疗SP疗效显著,有利于减轻患者中医证候,改善患者阴性症状,其作用机制可能与上调脑神经营养因子水平有关。 展开更多
关键词 精神分裂症 清心定志汤 高频rtms 阴性症状 脑神经营养因子
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阿立哌唑联合rTMS治疗精神分裂症患者临床症状与社会功能的影响
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作者 蔡玲玉 关海艳 +1 位作者 步宇 岳菲 《四川生理科学杂志》 2024年第4期825-827,共3页
目的:分析阿立哌唑联合重复经颅磁刺激(Repeated transcranial magnetic stimulation,rTMS)治疗精神分裂症患者对临床症状和社会功能的影响。方法:选取2021年1月至2022年12月期间本院收治的96例精神分裂症患者,随机将患者分成对照组和... 目的:分析阿立哌唑联合重复经颅磁刺激(Repeated transcranial magnetic stimulation,rTMS)治疗精神分裂症患者对临床症状和社会功能的影响。方法:选取2021年1月至2022年12月期间本院收治的96例精神分裂症患者,随机将患者分成对照组和研究组,每组各48人。对照组给予患者服用阿立哌唑治疗,研究组在对照组的基础上采取rTMS治疗。分析比较两组的临床疗效,临床症状以及社会功能。结果:研究组总有效率为93.75%,显著高于对照组的77.08%(P<0.05)。治疗后,两组的阳性与阴性症状量表(Positive and negative syndrome scale,PANSS)各项评分均显著低于治疗前,且研究组PANSS各项评分均显著低于对照组(P<0.05)。治疗后,两组社会功能量表(Personal and social performance Scale,PSP)评分均比治疗前显著上升,且研究组PSP评分显著高于对照组(P<0.05)。结论:阿立哌唑联合rTMS治疗精神分裂症能改善患者的临床症状,提升社会功能。 展开更多
关键词 阿立哌唑 rtms 精神分裂症 症状 社会功能
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综合护理联合rTMS对Wilson病患者吞咽障碍及负性情绪的影响
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作者 刘婷婷 王佳炜 +1 位作者 周水连 宋婷婷 《安徽医专学报》 2024年第3期63-65,共3页
目的:探讨综合护理联合rTMS对WD患者吞咽障碍及负性情绪的影响。方法:选取医院收治的72例伴吞咽障碍及负性情绪的WD患者,按随机数表法分为观察组(36例)和对照组(36例)。两组患者住院期间均给予驱铜治疗,对照组患者予以常规护理,并给予r... 目的:探讨综合护理联合rTMS对WD患者吞咽障碍及负性情绪的影响。方法:选取医院收治的72例伴吞咽障碍及负性情绪的WD患者,按随机数表法分为观察组(36例)和对照组(36例)。两组患者住院期间均给予驱铜治疗,对照组患者予以常规护理,并给予rTMS治疗;在对照组患者治疗基础上,给予观察组患者心理、康复等护理干预。采用WST、SSA、SDS和SAS等量表分别对两组患者治疗前后的抑郁、焦虑等负性情绪和吞咽功能进行测评并做比较,以进行疗效评估。结果:两组患者WST、SSA、SDS、SAS评分较治疗前均显著降低(P<0.05)。结论:在药物治疗的基础上,综合护理联合rTMS治疗可明显改善WD患者的吞咽障碍和负性情绪。 展开更多
关键词 综合护理 重复经颅磁刺激 WILSON病 吞咽障碍 负性情绪
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补阳还五汤加减联合低频rTMS治疗老年气虚血瘀型急性脑梗死的效果分析
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作者 蒋喜娟 《医学理论与实践》 2024年第10期1667-1669,共3页
目的:探讨补阳还五汤加减联合低频rTMS治疗对老年气虚血瘀型急性脑梗死(ACI)的效果。方法:选取我院2020年1月—2023年1月收治的老年气虚血瘀型ACI患者92例,根据治疗方案不同分为对照组和观察组,各46例。对照组在常规治疗基础上应用低频r... 目的:探讨补阳还五汤加减联合低频rTMS治疗对老年气虚血瘀型急性脑梗死(ACI)的效果。方法:选取我院2020年1月—2023年1月收治的老年气虚血瘀型ACI患者92例,根据治疗方案不同分为对照组和观察组,各46例。对照组在常规治疗基础上应用低频rTMS,观察组在对照组基础上加服补阳还五汤加减,评价两组治疗疗效。结果:治疗后,观察组中医证候积分显著低于对照组(P<0.05);观察组治疗总有效率93.48%,显著高于对照组的76.09%(P<0.05);相较于治疗前,两组治疗后美国国立卫生研究院卒中量表(NIHSS)评分明显减少,简易智能精神状态检查量表(MMSE)得分显著增加(P<0.05),而观察组减少/增加幅度更大(P<0.05);与治疗前相比,两组治疗后谷氨酸(Glu)、乙酰胆碱(ACh)和γ-氨基丁酸(GABA)水平明显降低、多巴胺(DA)显著升高(P<0.05),而观察组降低/升高幅度更大(P<0.05)。结论:补阳还五汤加减联合低频rTMS可有效缓解老年ACI患者的临床症状,促进神经和认知功能恢复,改善脑内神经递质水平。 展开更多
关键词 老年急性脑梗死 补阳还五汤 低频rtms 认知功能 脑神经递质
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采用舍曲林联合低频rTMS治疗抑郁症老年病人的有效性观察
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作者 夏玉梅 《中国科技期刊数据库 医药》 2024年第10期0005-0007,共3页
探究抑郁症老年病人在实行舍曲林以及低频rTMS治疗效果。方法 2023.1~2024.4阶段中,80名病人实行划分,对照组为其提供舍曲林治疗,观察组在其治疗之上为其提供低频rTMS治疗,数据汇总并分析。结果 治疗后观察组,抑郁程度逐步改善,神经递... 探究抑郁症老年病人在实行舍曲林以及低频rTMS治疗效果。方法 2023.1~2024.4阶段中,80名病人实行划分,对照组为其提供舍曲林治疗,观察组在其治疗之上为其提供低频rTMS治疗,数据汇总并分析。结果 治疗后观察组,抑郁程度逐步改善,神经递质水平逐步调节,患者认知功能逐步增强,生存质量提高,P<0.05。结论 抑郁症老年病人在实行治疗期间,为其通过舍曲林以及低频rTMS实行治疗,可以有效使患者抑郁程度逐步降低,令神经递质水平也得到调节,同时提高患者的认知以及生活质量。 展开更多
关键词 舍曲林 低频rtms 抑郁症老年病人
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rTMS联合舍曲林治疗对强迫症的认知功能影响
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作者 刘华斌 廖箐箐 +2 位作者 郑晓敏 姜荣亮 范雨花 《中国科技期刊数据库 医药》 2024年第4期0082-0086,共5页
探讨眶额叶皮质低频重复经颅磁刺激(rTMS)联合舍曲林治疗对强迫症患者认知功能的影响。方法 本研究以浙江省江山市第四人民医院住院患者为研究对象,于2019年5月-2023年5月间收治的强迫症病人60例,并将其分成两组,即30名和30名。实验组... 探讨眶额叶皮质低频重复经颅磁刺激(rTMS)联合舍曲林治疗对强迫症患者认知功能的影响。方法 本研究以浙江省江山市第四人民医院住院患者为研究对象,于2019年5月-2023年5月间收治的强迫症病人60例,并将其分成两组,即30名和30名。实验组与对照组在单纯药物治疗的基础上加用低频 rTMS治疗眶额叶区8周,而对照组则在单纯药物治疗的同时加用眶额叶区的低频 rTMS进行干预。疗效评估应用耶鲁-布朗强制量表(Yolu-Brown Compression Scale,Y-BOCS)评价基线后2、4、8周末对患者强迫症状进行评定,并应用威斯康辛量表(WCST)对其认知能力进行评价。结果 Y-BOCS评分和 WCST分级测试基线时比较,两组间差异均无显著性意义(P>0.05)。本研究通过Y-BOCS量表对两组病人进行了Y-BOCS评分的对比,结果显示:基线后,实验组病人的Y-BOCS得分、强迫思考因子均较基线降低,且有显著性差异。在治疗第8周,与基线相比,实验组和对照组的Y-BOCS评分(F=2865.330, P<0.01)、强迫思维因子分(F=956.071, P<0.01)、强迫行为因子分(F=419.306, P<0.01)均较基线显著降低,具有显著性(P<0.01)。两组的基线及治疗第8周的 WCST分级进行了对比,发现在治疗第8周时,观察组的虚假反应次数明显少于对照组,具有显著性(t=-1.982, P=0.048),观察组的随机错误数在治疗8周末的时候明显低于对照组,两者之间存在着显著的差别(t=-2.448, P=0.017),而观察组在治疗8周末的分组数明显高于对照组(t=1.896, P=0.039)。结论 眶额叶区低频rTMS刺激联合盐酸舍曲林治疗可有效改善强迫症症状和认知功能,安全性高,不良反应少,值得临床推广应用。 展开更多
关键词 强迫症 rtms 认知功能 舍曲林 威斯康辛卡片
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脑梗死后失语患者的语言功能训练结合rTMS康复治疗效果
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作者 陈凌峰 《中国科技期刊数据库 医药》 2024年第10期0168-0171,共4页
探究脑梗死后失语患者语言功能训练+rTMS的康复治疗效果。方法 选取脑梗死后失语患者,选取时间起始于2022.07,结束于2023.07,选取例数共88例,分组干预,方法 抽签分组,组别包括CED组、YGR组,每组例数44例。方法 rTMS康复治疗、语言功能训... 探究脑梗死后失语患者语言功能训练+rTMS的康复治疗效果。方法 选取脑梗死后失语患者,选取时间起始于2022.07,结束于2023.07,选取例数共88例,分组干预,方法 抽签分组,组别包括CED组、YGR组,每组例数44例。方法 rTMS康复治疗、语言功能训练+rTMS。对比:失语严重程度、日常生活沟通能力、治疗有效性、神经功能。结果 ①失语严重程度:YGR组患者(0级5例+1级5例+2级5例+3级14例+4级-5级15例)BDAE失语严重程度分级优于CED组(0级14例+1级5例+2级15例+3级5例+4级-5级5例),Z=6.176,P<0.05;②日常生活沟通能力(CFCP):治疗前(t=0.053、0.096、0.211、0.024、0.024、0.098,P=0.958、0.924、0.833、0.981、0.981、0.922)两组对比P>0.05,治疗后两组对比YGR组更高P<0.05;③治疗有效性(=4.062):YGR组95.45%(42/44)>CED组81.82%(36/44),P<0.05;④神经功能(NIHSS评分):治疗前(t=0.544)(9.53±1.42)分、(9.36±1.51)分,两组对比P>0.05,治疗后(t=8.014)(4.01±1.33)分<(6.45±1.52)分,两组对比YGR组更低P<0.05。结论 在脑梗死后失语患者护理中实施语言功能训练结合rTMS康复治疗能提升患者治疗效果,改善语言功能与神经功能,值得推广实施。 展开更多
关键词 脑梗死 失语 语言功能训练 rtms 康复治疗 效果
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