目的探索腰椎间盘突出症患者术后下肢深静脉血栓(deep vein thrombosis,DVT)形成的影响因素及富亮氨酸重复序列相互作用蛋白1(leucine rich repeat in flii interacting protein 1,LRRFIP1)的表达意义。方法分析2018年1月~2020年6月收治...目的探索腰椎间盘突出症患者术后下肢深静脉血栓(deep vein thrombosis,DVT)形成的影响因素及富亮氨酸重复序列相互作用蛋白1(leucine rich repeat in flii interacting protein 1,LRRFIP1)的表达意义。方法分析2018年1月~2020年6月收治的119例腰椎间盘突出症患者,根据患者术后是否合并下肢DVT分为两组,即34例DVT组,85例非DVT组。对比两组一般资料后,经二元Logistic回归分析独立影响因素,再经Spearman相关性分析术后下肢DVT形成与独立影响因素的相关性,以分析LRRFIP1表达与DVT的相关性,用ROC曲线分析各项指标的预测价值。结果经二元Logistic回归分析,年龄、BMI、PLT、MPV、PT、APTT、FIB、D-二聚体水平是影响术后下肢DVT形成的独立影响因子。经Spearman相关性分析,术后下肢DVT形成与年龄、BMI、PLT、PT、APTT呈负相关性;与MPV、FIB、D-二聚体呈正相关性(P<0.05)。经Pearson法分析,LRRFIP1表达与PT、APTT呈负相关性,与FIB、D-二聚体呈正相关性。经ROC曲线分析,年龄、BMI、MPV、APTT、LRRFIP1表达、PLT、PT、FIB、D二聚体早期预测术后下肢DVT形成的AUC分别为0.665、0.662、0.733、0.773、0.94、0.984、0.817、0.673、0.976。结论年龄、BMI、凝血功能、血小板指标等均是影响腰椎间盘突出症患者术后下肢DVT形成的独立因子;LRRFIP1表达上调意味着腰椎间盘突出症患者存在血液高凝状态,与DVT发生率存在一定的相关性。展开更多
Aim and Objectives: This study aimed to record the commonly affected veins in the lower limbs, to compare the affected sides and gender and to correlate the Doppler findings and stages of deep venous thrombosis (DVT)....Aim and Objectives: This study aimed to record the commonly affected veins in the lower limbs, to compare the affected sides and gender and to correlate the Doppler findings and stages of deep venous thrombosis (DVT). Materials and Methods: A descriptive retrospective study of 46 already diagnosed cases of lower limb DVT. Results: Out of 46 cases of DVT, 71.74% were females. The majority of patients (93.47%) were affected in unilateral lower limb with significant predominance (65.22%) to affect the left lower limb (p Conclusion: Lower limb deep venous thrombosis affects left lower limb more than right and females more than males. Superficial femoral vein (SFV) and common femoral vein (CFV) are the most common affected veins. Lower limb DVT predominantly present in acute stage with venous distension and absent blood flow.展开更多
文摘目的探索腰椎间盘突出症患者术后下肢深静脉血栓(deep vein thrombosis,DVT)形成的影响因素及富亮氨酸重复序列相互作用蛋白1(leucine rich repeat in flii interacting protein 1,LRRFIP1)的表达意义。方法分析2018年1月~2020年6月收治的119例腰椎间盘突出症患者,根据患者术后是否合并下肢DVT分为两组,即34例DVT组,85例非DVT组。对比两组一般资料后,经二元Logistic回归分析独立影响因素,再经Spearman相关性分析术后下肢DVT形成与独立影响因素的相关性,以分析LRRFIP1表达与DVT的相关性,用ROC曲线分析各项指标的预测价值。结果经二元Logistic回归分析,年龄、BMI、PLT、MPV、PT、APTT、FIB、D-二聚体水平是影响术后下肢DVT形成的独立影响因子。经Spearman相关性分析,术后下肢DVT形成与年龄、BMI、PLT、PT、APTT呈负相关性;与MPV、FIB、D-二聚体呈正相关性(P<0.05)。经Pearson法分析,LRRFIP1表达与PT、APTT呈负相关性,与FIB、D-二聚体呈正相关性。经ROC曲线分析,年龄、BMI、MPV、APTT、LRRFIP1表达、PLT、PT、FIB、D二聚体早期预测术后下肢DVT形成的AUC分别为0.665、0.662、0.733、0.773、0.94、0.984、0.817、0.673、0.976。结论年龄、BMI、凝血功能、血小板指标等均是影响腰椎间盘突出症患者术后下肢DVT形成的独立因子;LRRFIP1表达上调意味着腰椎间盘突出症患者存在血液高凝状态,与DVT发生率存在一定的相关性。
文摘Aim and Objectives: This study aimed to record the commonly affected veins in the lower limbs, to compare the affected sides and gender and to correlate the Doppler findings and stages of deep venous thrombosis (DVT). Materials and Methods: A descriptive retrospective study of 46 already diagnosed cases of lower limb DVT. Results: Out of 46 cases of DVT, 71.74% were females. The majority of patients (93.47%) were affected in unilateral lower limb with significant predominance (65.22%) to affect the left lower limb (p Conclusion: Lower limb deep venous thrombosis affects left lower limb more than right and females more than males. Superficial femoral vein (SFV) and common femoral vein (CFV) are the most common affected veins. Lower limb DVT predominantly present in acute stage with venous distension and absent blood flow.
