This paper investigates the global stability of a viral infection model with lytic immune response. If the basic reproductive ratio of the virus is less than or equal to one, by the LaSalle＇s invariance principle, th...This paper investigates the global stability of a viral infection model with lytic immune response. If the basic reproductive ratio of the virus is less than or equal to one, by the LaSalle＇s invariance principle, the disease-free steady state is globally asymptotically stable. If the basic reproductive ratio of the virus is greater than one but less than or equal to a constant, which is defined by the parameters of the model, then the immune-exhausted steady state is globally asymptotically stable. The endemic steady state is globally asymptotically stable if the inverse is valid.展开更多
基金Research supported by the National Science Fund of P. R. China (No: 10271096, 10101029, 30400209) the Science Fund of Southwest China Normal University.
文摘This paper investigates the global stability of a viral infection model with lytic immune response. If the basic reproductive ratio of the virus is less than or equal to one, by the LaSalle＇s invariance principle, the disease-free steady state is globally asymptotically stable. If the basic reproductive ratio of the virus is greater than one but less than or equal to a constant, which is defined by the parameters of the model, then the immune-exhausted steady state is globally asymptotically stable. The endemic steady state is globally asymptotically stable if the inverse is valid.
