Aim To determine efficiency of multi-range hydro-mechanical stepless transmis- sion(HMT).Methods Ageneral model of HMT was of HMT was structured.On the basis of power flow analysis, the efficiency was obtained,Results...Aim To determine efficiency of multi-range hydro-mechanical stepless transmis- sion(HMT).Methods Ageneral model of HMT was of HMT was structured.On the basis of power flow analysis, the efficiency was obtained,Results efficiency of multi-range HMT changes continuously with output speed in speed range and is higher than the highest point of the hydraulic efficiency,The volumetric efficiency can potentially result in the speed fluctuation, which can be reduced or eliminated through controlling the ratio of the displacements ofhydraulic unity properly or changing the point of range exchanging .And the mechanical- constant output torque or different output torque under the condition of constant pressure when the transmission works in different parts of a range,Conclusion The multi-range HMT is an ideal stepless transmission with high efficiency.展开更多
Worldwide, scarce water resources and substantial food demands require efficient water use and high yield.This study investigated whether irrigation frequency can be used to adjust soil moisture to increase grain yiel...Worldwide, scarce water resources and substantial food demands require efficient water use and high yield.This study investigated whether irrigation frequency can be used to adjust soil moisture to increase grain yield and water use efficiency(WUE) of high-yield maize under conditions of mulching and drip irrigation.A field experiment was conducted using three irrigation intervals in 2016: 6, 9, and 12 days(labeled D6, D9, and D12) and five irrigation intervals in 2017: 3, 6, 9, 12, and 15 days(D3, D6, D9, D12, and D15).In Xinjiang, an optimal irrigation quota is 540 mm for high-yield maize.The D3, D6, D9, D12, and D15 irrigation intervals gave grain yields of 19.7, 19.1–21.0, 18.8–20.0, 18.2–19.2, and 17.2 Mg ha^-1 and a WUE of 2.48, 2.53–2.80, 2.47–2.63, 2.34–2.45, and 2.08 kg m-3, respectively.Treatment D6 led to the highest soil water storage, but evapotranspiration and soil-water evaporation were lower than other treatments.These results show that irrigation interval D6 can help maintain a favorable soil-moisture environment in the upper-60-cm soil layer, reduce soilwater evaporation and evapotranspiration, and produce the highest yield and WUE.In this arid region and in other regions with similar soil and climate conditions, a similar irrigation interval would thus be beneficial for adjusting soil moisture to increase maize yield and WUE under conditions of mulching and drip irrigation.展开更多
Antioxidant efficiency was studied in fresh edible algae: Cladophora, Microspara and Nostochopsis spp. from Nan River, Nan province. The samples were collected from Pua and Tha-Wang-Pha district, studied antioxidant ...Antioxidant efficiency was studied in fresh edible algae: Cladophora, Microspara and Nostochopsis spp. from Nan River, Nan province. The samples were collected from Pua and Tha-Wang-Pha district, studied antioxidant activity and compared the antioxidant efficacy of the extracts from the three fresh edible algae with a standard solution, 3-tert-butyl-4-hydroxyanisole (BHA). This study found that an extract ofNostochopsis spp. was the highest antioxidant activity to DPPH free radical between 32.1 and 87.5, the highest amount of beta-carotene was 4.71-7.09 mg/g and the highest amount of phenol in fresh edible algae extracts from Microspora was between 9.37 and 37.02 mg/g. The highest vitamin C in Microspora was between 110.41-138.53 mg/100 g.展开更多
A highly efficient and convenient procedure for the enantioselective synthesis of (S)-Rivastigmine, a cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type and dementia due to Parki...A highly efficient and convenient procedure for the enantioselective synthesis of (S)-Rivastigmine, a cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type and dementia due to Parkinson’s disease, is accomplished by the treatment of versatile, readily accessible (S)-(-)-2-methyl-2-propanesulfinamide with 3-hydroxyacetophenone. This protocol provides high yield and excellent enantiomeric excess in short step synthesis.展开更多
Increasing complexity of distributed hydrological model (DHM) has lowered the efficiency of convergence.In this study,global sensitivity analysis (SA) was introduced by combining multiobjective (MO) optimization...Increasing complexity of distributed hydrological model (DHM) has lowered the efficiency of convergence.In this study,global sensitivity analysis (SA) was introduced by combining multiobjective (MO) optimization for DHM calibration.Latin Hypercube-once at a time (LH-OAT) was adopted in global parameter SA to obtain relative sensitivity of model parameter,which can be categorized into different sensitivity levels.Two comparative study cases were conducted to present the efficiency and feasibility by combining SA with MO(SA-MO).WetSpa model with non-dominated sorting genetic algorithm-Ⅱ (NSGA-Ⅱ) algorithm and EasyDHM model with multi-objective sequential complex evolutionary metropolis-uncertainty analysis (MOSCEM-UA)algorithm were adopted to demonstrate the general feasibility of combining SA in optimization.Results showed that the LH-OAT was globally effective in selecting high sensitivity parameters.It proves that using parameter from high sensitivity groups results in higher convergence efficiency.Study case Ⅰ showed a better Pareto front distribution and convergence compared with model calibration without SA.Study case Ⅱ indicated a more efficient convergence of parameters in sequential evolution of MOSCEM-UA under the same iteration.It indicates that SA-MO is feasible and efficient for high dimensional DHM calibration.展开更多
CO2 flooding is regarded as an important method for enhanced oil recovery (EOR) and greenhouse gas control. However, the heterogeneity prevalently dis- tributed in reservoirs inhibits the performance of this technol...CO2 flooding is regarded as an important method for enhanced oil recovery (EOR) and greenhouse gas control. However, the heterogeneity prevalently dis- tributed in reservoirs inhibits the performance of this technology. The sweep efficiency can be significantly reduced especially in the presence of "thief zones". Hence, gas channeling blocking and mobility control are important technical issues for the success of CO2 injection. Normally, crosslinked gels have the potential to block gas channels, but the gelation time control poses challenges to this method. In this study, a new method for selectively blocking CO2 channeling is proposed, which is based on a type of CO2-sensitive gel system (modified polyacry- lamide-methenamine-resorcinol gel system) to form gel in situ. A CO2-sensitive gel system is when gelation or solidification will be triggered by CO2 in the reservoir to block gas channels. The CO2-sensitivity of the gel system was demonstrated in parallel bottle tests of gel in N2 and CO2 atmospheres. Sand pack flow experiments were con- ducted to investigate the shutoff capacity of the gel system under different conditions. The injectivity of the gel system was studied via viscosity measurements. The results indi- cate that this gel system was sensitive to CO2 and had good performance of channeling blocking in porous media. Advantageous viscosity-temperature characteristics were achieved in this work. The effectiveness for EOR in heterogeneous formations based on this gel system was demonstrated using displacement tests conducted in double sand packs. The experimental results can provide guideli- nes for the deployment of theCO2-sensitive gel system for field applications.展开更多
Multiple nitrate transporter(NRT)genes exist in the genome of bread wheat,and it is of great importance to identify the elite NRT genes for N-efficient wheat cultivar breeding.A candidate gene association study(CGAS)o...Multiple nitrate transporter(NRT)genes exist in the genome of bread wheat,and it is of great importance to identify the elite NRT genes for N-efficient wheat cultivar breeding.A candidate gene association study(CGAS)of six N use efficiency(NUE)related traits(grain N concentration(GNC),straw N concentration(SNC),grain yield(GY),grain N accumulation(GNA),shoot total N accumulation(STN)and N harvest index(NHI))was performed based on SNPs in 46 NRT2 genes using a panel composed of 286 wheat cultivars.CGAS identified TaNRT2.1-6B as an elite NRT gene that is significantly associated with four(NHI,SNC,GNA and GY)of the six NUE-related traits simultaneously.TaNRT2.1-6B is located on the plasma membrane and acts as a dual-affinity NRT.The overexpression of TaNRT2.1-6B increased the N influx and root growth of wheat,whereas gene silence lines resulted in the opposite effects.The overexpression of TaNRT2.1-6B also improved GY and N accumulation of wheat under either limited or sufficient N conditions.The data provide the TaNRT2.1-6B gene and the two associated SNP markers as promising powerful tools for breeding wheat cultivars with high N uptake ability and NUE.展开更多
Multiple regression equations of liquidus temperature, electrical conductivity and bath density of the Na_3AlF_6-AlF_3-BaC1_2-NaCl system were obtained from experiments by using orthogonal regression method. The exper...Multiple regression equations of liquidus temperature, electrical conductivity and bath density of the Na_3AlF_6-AlF_3-BaC1_2-NaCl system were obtained from experiments by using orthogonal regression method. The experiments were carried out in 100A cell with low melting point electrolyte, the influences of cathodic current density, electrolytic temperature, density differences of bath and liquid aluminum on current efficiency (CE) were studied; when the electrolyte cryolite ratio was 2.5, w(BaC1_2) and w(NaCl) were 48% and 10%, respectively, CE reached 90% and specific energy consumption was 10.97k Wb/kg/kg. Because of the fact that aluminum metal obtained floated on the surface of molten electrolyte, this electrolysis method was then defined as low temperature aluminum floating electrolysis. The results showed that the new low temperature aluminum electrolysis process in the Na_3AlF_6-AlF_3-BaC1_2-NaCl bath system was practical and promising.展开更多
Photocatalytic H2 evolution reactions on pristine graphitic carbon nitrides(g-C3N4),as a promising approach for converting solar energy to fuel,are attractive for tackling global energy concerns but still suffer from ...Photocatalytic H2 evolution reactions on pristine graphitic carbon nitrides(g-C3N4),as a promising approach for converting solar energy to fuel,are attractive for tackling global energy concerns but still suffer from low efficiencies.In this article,we report a tractable approach to modifying g-C3N4 with vanadyl phthalocyanine(VOPc/CN)for efficient visible-light-driven hydrogen production.A non-covalent VOPc/CN hybrid photocatalyst formed viaπ-πstacking interactions between the two components,as confirmed by analysis of UV-vis absorption spectra.The VOPc/CN hybrid photocatalyst shows excellent visible-light-driven photocatalytic performance and good stability.Under optimal conditions,the corresponding H2 evolution rate is nearly 6 times higher than that of pure g-C3N4.The role of VOPc in promoting hydrogen evolution activity was to extend the visible light absorption range and prevent the recombination of photoexcited electron-hole pairs effectively.It is expected that this facile modification method could be a new inspiration for the rational design and exploration of g-C3N4-based hybrid systems with strong light absorption and high-efficiency carrier separation.展开更多
Condensation technique of degree of freedom is first proposed to improve the computational efficiency of meshfree method with Galerkin weak form for elastic dy- namic analysis. In the present method, scattered nodes w...Condensation technique of degree of freedom is first proposed to improve the computational efficiency of meshfree method with Galerkin weak form for elastic dy- namic analysis. In the present method, scattered nodes with- out connectivity are divided into several subsets by cells with arbitrary shape. Local discrete equation is established over each cell by using moving Kriging interpolation, in which the nodes that located in the cell are used for approxima- tion. Then local discrete equations can be simplified by con- densation of degree of freedom, which transfers equations of inner nodes to equations of boundary nodes based on cells. The global dynamic system equations are obtained by as- sembling all local discrete equations and are solved by using the standard implicit Newmark's time integration scheme. In the scheme of present method, the calculation of each cell is carried out by meshfree method, and local search is imple- mented in interpolation. Numerical examples show that the present method has high computational efficiency and good accuracy in solving elastic dynamic problems.展开更多
Multijunction solar cells are the highest efficiency photovoltaic devices yet demonstrated for both space and terrestrial applications.In recent years five-junction cells based on the direct semiconductor bonding tech...Multijunction solar cells are the highest efficiency photovoltaic devices yet demonstrated for both space and terrestrial applications.In recent years five-junction cells based on the direct semiconductor bonding technique(SBT),demonstrates space efficiencies>35%and presents application potentials.In this paper,the major challenges for fabricating SBT 5J cells and their appropriate strategies involving structure tunning,band engineering and material tailoring are stated,and 4-cm235.4%(AM0,one sun)5J SBT cells are presented.Further efforts on detailed optical managements are required to improve the current generating and matching in subcells,to achieve efficiencies 36%-37%,or above.展开更多
A new kind of bio-fluid bed used to treat dyes wastewater is described in detail due to its several special features,such as high removal efficiency,simple struc-ture,shock load resistance,etc.By means of analyzing th...A new kind of bio-fluid bed used to treat dyes wastewater is described in detail due to its several special features,such as high removal efficiency,simple struc-ture,shock load resistance,etc.By means of analyzing the experiment data,the results show that the dye wastewater’s organic matter is removed greatly after be-ing treated by this new kind of bio-fluid bed.On the other hand,the removal efficiency of chromaticity of展开更多
To relax convexity assumptions imposed on the functions in theorems on sufficient conditions and duality,new concepts of generalized dI-G-type Ⅰ invexity were introduced for nondifferentiable multiobjective programmi...To relax convexity assumptions imposed on the functions in theorems on sufficient conditions and duality,new concepts of generalized dI-G-type Ⅰ invexity were introduced for nondifferentiable multiobjective programming problems.Based upon these generalized invexity,G-Fritz-John (G-F-J) and G-Karnsh-Kuhn-Tucker (G-K-K-T) types sufficient optimality conditions were established for a feasible solution to be an efficient solution.Moreover,weak and strict duality results were derived for a G-Mond-Weir type dual under various types of generalized dI-G-type Ⅰ invexity assumptions.展开更多
Precise targeting of specific regions within the central nervous system(CNS)is crucial for both scientific research and gene therapy in the context of brain diseases.Adeno-associated virus 13(AAV13)is known for its re...Precise targeting of specific regions within the central nervous system(CNS)is crucial for both scientific research and gene therapy in the context of brain diseases.Adeno-associated virus 13(AAV13)is known for its restricted diffusion range within the CNS,making it an ideal choice for precise labeling and administration within small brain regions.However,AAV13 mediates relatively low expression of target genes.Here,we introduced specifically engineered modifications to the AAV13 capsid protein to enhance its transduction efficiency.We first constructed AAV13-YF by mutating tyrosine to phenylalanine on the surface of the AAV13 capsid.We then inserted the 7m8 peptide,known to enhance cell transduction,into positions 587/588 and 585/586 of the AAV13 capsid,resulting in two distinct variants named AAV13-587-7m8 and AAV13-585-7m8,respectively.We found that AAV13-YF exhibited superior in vitro infectivity in HEK293T cells compared to AAV13,while AAV13-587-7m8 and AAV13-585-7m8 showed enhanced CNS infection capabilities in C57BL/6 mice,with AAV13-587-7m8 infection retaining a limited spread range.These modified AAV13 variants hold promising potential for applications in gene therapy and neuroscience research.展开更多
文摘Aim To determine efficiency of multi-range hydro-mechanical stepless transmis- sion(HMT).Methods Ageneral model of HMT was of HMT was structured.On the basis of power flow analysis, the efficiency was obtained,Results efficiency of multi-range HMT changes continuously with output speed in speed range and is higher than the highest point of the hydraulic efficiency,The volumetric efficiency can potentially result in the speed fluctuation, which can be reduced or eliminated through controlling the ratio of the displacements ofhydraulic unity properly or changing the point of range exchanging .And the mechanical- constant output torque or different output torque under the condition of constant pressure when the transmission works in different parts of a range,Conclusion The multi-range HMT is an ideal stepless transmission with high efficiency.
基金research support from the National Key Research and Development Program of China (2016YFD0300110, 2016YFD0300101)the National Basic Research Program of China (2015CB150401)+2 种基金the National Natural Science Foundation of China (31360302)the Science and Technology Program of the Sixth Division of Xinjiang Construction Corps in China (1703)the Agricultural Science and Technology Innovation Program for financial support.
文摘Worldwide, scarce water resources and substantial food demands require efficient water use and high yield.This study investigated whether irrigation frequency can be used to adjust soil moisture to increase grain yield and water use efficiency(WUE) of high-yield maize under conditions of mulching and drip irrigation.A field experiment was conducted using three irrigation intervals in 2016: 6, 9, and 12 days(labeled D6, D9, and D12) and five irrigation intervals in 2017: 3, 6, 9, 12, and 15 days(D3, D6, D9, D12, and D15).In Xinjiang, an optimal irrigation quota is 540 mm for high-yield maize.The D3, D6, D9, D12, and D15 irrigation intervals gave grain yields of 19.7, 19.1–21.0, 18.8–20.0, 18.2–19.2, and 17.2 Mg ha^-1 and a WUE of 2.48, 2.53–2.80, 2.47–2.63, 2.34–2.45, and 2.08 kg m-3, respectively.Treatment D6 led to the highest soil water storage, but evapotranspiration and soil-water evaporation were lower than other treatments.These results show that irrigation interval D6 can help maintain a favorable soil-moisture environment in the upper-60-cm soil layer, reduce soilwater evaporation and evapotranspiration, and produce the highest yield and WUE.In this arid region and in other regions with similar soil and climate conditions, a similar irrigation interval would thus be beneficial for adjusting soil moisture to increase maize yield and WUE under conditions of mulching and drip irrigation.
文摘Antioxidant efficiency was studied in fresh edible algae: Cladophora, Microspara and Nostochopsis spp. from Nan River, Nan province. The samples were collected from Pua and Tha-Wang-Pha district, studied antioxidant activity and compared the antioxidant efficacy of the extracts from the three fresh edible algae with a standard solution, 3-tert-butyl-4-hydroxyanisole (BHA). This study found that an extract ofNostochopsis spp. was the highest antioxidant activity to DPPH free radical between 32.1 and 87.5, the highest amount of beta-carotene was 4.71-7.09 mg/g and the highest amount of phenol in fresh edible algae extracts from Microspora was between 9.37 and 37.02 mg/g. The highest vitamin C in Microspora was between 110.41-138.53 mg/100 g.
文摘A highly efficient and convenient procedure for the enantioselective synthesis of (S)-Rivastigmine, a cholinergic agent for the treatment of mild to moderate dementia of the Alzheimer’s type and dementia due to Parkinson’s disease, is accomplished by the treatment of versatile, readily accessible (S)-(-)-2-methyl-2-propanesulfinamide with 3-hydroxyacetophenone. This protocol provides high yield and excellent enantiomeric excess in short step synthesis.
基金National Basic Research Program(973)of China(No.2010CB951102)Innovative Research Groups of the National Natural Science Foundation,China(No.51021006)National Natural Science Foundation of China(No.51079028)
文摘Increasing complexity of distributed hydrological model (DHM) has lowered the efficiency of convergence.In this study,global sensitivity analysis (SA) was introduced by combining multiobjective (MO) optimization for DHM calibration.Latin Hypercube-once at a time (LH-OAT) was adopted in global parameter SA to obtain relative sensitivity of model parameter,which can be categorized into different sensitivity levels.Two comparative study cases were conducted to present the efficiency and feasibility by combining SA with MO(SA-MO).WetSpa model with non-dominated sorting genetic algorithm-Ⅱ (NSGA-Ⅱ) algorithm and EasyDHM model with multi-objective sequential complex evolutionary metropolis-uncertainty analysis (MOSCEM-UA)algorithm were adopted to demonstrate the general feasibility of combining SA in optimization.Results showed that the LH-OAT was globally effective in selecting high sensitivity parameters.It proves that using parameter from high sensitivity groups results in higher convergence efficiency.Study case Ⅰ showed a better Pareto front distribution and convergence compared with model calibration without SA.Study case Ⅱ indicated a more efficient convergence of parameters in sequential evolution of MOSCEM-UA under the same iteration.It indicates that SA-MO is feasible and efficient for high dimensional DHM calibration.
基金financial support from the National Basic Research Program of China(2015CB251201)the Fundamental Research Funds for the Central Universities(15CX06024A)the Program for Changjiang Scholars and Innovative Research Team in University(IRT1294 and IRT1086)
文摘CO2 flooding is regarded as an important method for enhanced oil recovery (EOR) and greenhouse gas control. However, the heterogeneity prevalently dis- tributed in reservoirs inhibits the performance of this technology. The sweep efficiency can be significantly reduced especially in the presence of "thief zones". Hence, gas channeling blocking and mobility control are important technical issues for the success of CO2 injection. Normally, crosslinked gels have the potential to block gas channels, but the gelation time control poses challenges to this method. In this study, a new method for selectively blocking CO2 channeling is proposed, which is based on a type of CO2-sensitive gel system (modified polyacry- lamide-methenamine-resorcinol gel system) to form gel in situ. A CO2-sensitive gel system is when gelation or solidification will be triggered by CO2 in the reservoir to block gas channels. The CO2-sensitivity of the gel system was demonstrated in parallel bottle tests of gel in N2 and CO2 atmospheres. Sand pack flow experiments were con- ducted to investigate the shutoff capacity of the gel system under different conditions. The injectivity of the gel system was studied via viscosity measurements. The results indi- cate that this gel system was sensitive to CO2 and had good performance of channeling blocking in porous media. Advantageous viscosity-temperature characteristics were achieved in this work. The effectiveness for EOR in heterogeneous formations based on this gel system was demonstrated using displacement tests conducted in double sand packs. The experimental results can provide guideli- nes for the deployment of theCO2-sensitive gel system for field applications.
基金funded by the National Natural Science Foundation of China(31972497).
文摘Multiple nitrate transporter(NRT)genes exist in the genome of bread wheat,and it is of great importance to identify the elite NRT genes for N-efficient wheat cultivar breeding.A candidate gene association study(CGAS)of six N use efficiency(NUE)related traits(grain N concentration(GNC),straw N concentration(SNC),grain yield(GY),grain N accumulation(GNA),shoot total N accumulation(STN)and N harvest index(NHI))was performed based on SNPs in 46 NRT2 genes using a panel composed of 286 wheat cultivars.CGAS identified TaNRT2.1-6B as an elite NRT gene that is significantly associated with four(NHI,SNC,GNA and GY)of the six NUE-related traits simultaneously.TaNRT2.1-6B is located on the plasma membrane and acts as a dual-affinity NRT.The overexpression of TaNRT2.1-6B increased the N influx and root growth of wheat,whereas gene silence lines resulted in the opposite effects.The overexpression of TaNRT2.1-6B also improved GY and N accumulation of wheat under either limited or sufficient N conditions.The data provide the TaNRT2.1-6B gene and the two associated SNP markers as promising powerful tools for breeding wheat cultivars with high N uptake ability and NUE.
基金The project was financially supported by the National Natural Science Foundation of China! (Gmnt No.59574018)China Postdocto
文摘Multiple regression equations of liquidus temperature, electrical conductivity and bath density of the Na_3AlF_6-AlF_3-BaC1_2-NaCl system were obtained from experiments by using orthogonal regression method. The experiments were carried out in 100A cell with low melting point electrolyte, the influences of cathodic current density, electrolytic temperature, density differences of bath and liquid aluminum on current efficiency (CE) were studied; when the electrolyte cryolite ratio was 2.5, w(BaC1_2) and w(NaCl) were 48% and 10%, respectively, CE reached 90% and specific energy consumption was 10.97k Wb/kg/kg. Because of the fact that aluminum metal obtained floated on the surface of molten electrolyte, this electrolysis method was then defined as low temperature aluminum floating electrolysis. The results showed that the new low temperature aluminum electrolysis process in the Na_3AlF_6-AlF_3-BaC1_2-NaCl bath system was practical and promising.
基金supported by the National Natural Science Foundation of China(51572253,21771171)Scientific Research Grant of Hefei National Synchrotron Radiation Laboratory(UN2017LHJJ)+1 种基金the Fundamental Research Funds for the Central Universitiescooperation between NSFC and Netherlands Organization for Scientific Research(51561135011)~~
文摘Photocatalytic H2 evolution reactions on pristine graphitic carbon nitrides(g-C3N4),as a promising approach for converting solar energy to fuel,are attractive for tackling global energy concerns but still suffer from low efficiencies.In this article,we report a tractable approach to modifying g-C3N4 with vanadyl phthalocyanine(VOPc/CN)for efficient visible-light-driven hydrogen production.A non-covalent VOPc/CN hybrid photocatalyst formed viaπ-πstacking interactions between the two components,as confirmed by analysis of UV-vis absorption spectra.The VOPc/CN hybrid photocatalyst shows excellent visible-light-driven photocatalytic performance and good stability.Under optimal conditions,the corresponding H2 evolution rate is nearly 6 times higher than that of pure g-C3N4.The role of VOPc in promoting hydrogen evolution activity was to extend the visible light absorption range and prevent the recombination of photoexcited electron-hole pairs effectively.It is expected that this facile modification method could be a new inspiration for the rational design and exploration of g-C3N4-based hybrid systems with strong light absorption and high-efficiency carrier separation.
基金supported by the National Natural Science Founda-tion of China(11272118)Open Found of State Key Laboratory of Explosion Science and Technology(KFJJ12-5M)
文摘Condensation technique of degree of freedom is first proposed to improve the computational efficiency of meshfree method with Galerkin weak form for elastic dy- namic analysis. In the present method, scattered nodes with- out connectivity are divided into several subsets by cells with arbitrary shape. Local discrete equation is established over each cell by using moving Kriging interpolation, in which the nodes that located in the cell are used for approxima- tion. Then local discrete equations can be simplified by con- densation of degree of freedom, which transfers equations of inner nodes to equations of boundary nodes based on cells. The global dynamic system equations are obtained by as- sembling all local discrete equations and are solved by using the standard implicit Newmark's time integration scheme. In the scheme of present method, the calculation of each cell is carried out by meshfree method, and local search is imple- mented in interpolation. Numerical examples show that the present method has high computational efficiency and good accuracy in solving elastic dynamic problems.
基金supported by the National Nature Science Foundation of China(Grant No.62004126)Shanghai Rising-Star Program(Grant No.19QB1403800).
文摘Multijunction solar cells are the highest efficiency photovoltaic devices yet demonstrated for both space and terrestrial applications.In recent years five-junction cells based on the direct semiconductor bonding technique(SBT),demonstrates space efficiencies>35%and presents application potentials.In this paper,the major challenges for fabricating SBT 5J cells and their appropriate strategies involving structure tunning,band engineering and material tailoring are stated,and 4-cm235.4%(AM0,one sun)5J SBT cells are presented.Further efforts on detailed optical managements are required to improve the current generating and matching in subcells,to achieve efficiencies 36%-37%,or above.
文摘A new kind of bio-fluid bed used to treat dyes wastewater is described in detail due to its several special features,such as high removal efficiency,simple struc-ture,shock load resistance,etc.By means of analyzing the experiment data,the results show that the dye wastewater’s organic matter is removed greatly after be-ing treated by this new kind of bio-fluid bed.On the other hand,the removal efficiency of chromaticity of
基金National Natural Science Foundation of China(No.11071110)
文摘To relax convexity assumptions imposed on the functions in theorems on sufficient conditions and duality,new concepts of generalized dI-G-type Ⅰ invexity were introduced for nondifferentiable multiobjective programming problems.Based upon these generalized invexity,G-Fritz-John (G-F-J) and G-Karnsh-Kuhn-Tucker (G-K-K-T) types sufficient optimality conditions were established for a feasible solution to be an efficient solution.Moreover,weak and strict duality results were derived for a G-Mond-Weir type dual under various types of generalized dI-G-type Ⅰ invexity assumptions.
基金National Science and Technology Innovation 2030 Grant(2021ZD0201003)National Natural Science Foundation of China(31830035,31771156,21921004)+2 种基金Strategic Priority Research Program of the Chinese Academy of Sciences(XDB32030200)Shenzhen Key Laboratory of Viral Vectors for Biomedicine(ZDSYS20200811142401005)Key Laboratory of Quality Control Technology for Virus-Based Therapeutics,Guangdong Provincial Medical Products Administration(2022ZDZ13)。
文摘Precise targeting of specific regions within the central nervous system(CNS)is crucial for both scientific research and gene therapy in the context of brain diseases.Adeno-associated virus 13(AAV13)is known for its restricted diffusion range within the CNS,making it an ideal choice for precise labeling and administration within small brain regions.However,AAV13 mediates relatively low expression of target genes.Here,we introduced specifically engineered modifications to the AAV13 capsid protein to enhance its transduction efficiency.We first constructed AAV13-YF by mutating tyrosine to phenylalanine on the surface of the AAV13 capsid.We then inserted the 7m8 peptide,known to enhance cell transduction,into positions 587/588 and 585/586 of the AAV13 capsid,resulting in two distinct variants named AAV13-587-7m8 and AAV13-585-7m8,respectively.We found that AAV13-YF exhibited superior in vitro infectivity in HEK293T cells compared to AAV13,while AAV13-587-7m8 and AAV13-585-7m8 showed enhanced CNS infection capabilities in C57BL/6 mice,with AAV13-587-7m8 infection retaining a limited spread range.These modified AAV13 variants hold promising potential for applications in gene therapy and neuroscience research.