Binary wolf pack algorithm (BWPA) is a kind of intelligence algorithm which can solve combination optimization problems in discrete spaces.Based on BWPA, an improved binary wolf pack algorithm (AIBWPA) can be proposed...Binary wolf pack algorithm (BWPA) is a kind of intelligence algorithm which can solve combination optimization problems in discrete spaces.Based on BWPA, an improved binary wolf pack algorithm (AIBWPA) can be proposed by adopting adaptive step length and improved update strategy of wolf pack. AIBWPA is applied to 10 classic 0-1 knapsack problems and compared with BWPA, DPSO, which proves that AIBWPA has higher optimization accuracy and better computational robustness. AIBWPA makes the parameters simple, protects the population diversity and enhances the global convergence.展开更多
Background: Globally, UNAIDS report 2022 shows, there are 84.2 million people affected by HIV/AIDS and 40.1 million deaths from AIDS since the start of epidemic. In sub-Saharan Africa, women and girls accounted for 63...Background: Globally, UNAIDS report 2022 shows, there are 84.2 million people affected by HIV/AIDS and 40.1 million deaths from AIDS since the start of epidemic. In sub-Saharan Africa, women and girls accounted for 63% of all new HIV infections in 2021 with, six in seven new HIV infections among adolescents aged 15 - 19 years being girls. Key populations accounted for 70% of HIV infections globally in 2021, with 51% of these new HIV infections in sub-Saharan Africa. Reflecting on the 4 decades’ journey of HIV epidemic amidst local, national and international efforts, the UN target of ending AIDS as a public health threat by 2030 remains questionable unless new innovative ways are used. This study aimed at analyzing existing HIV/AIDS interventions, discuss UN interventions in line with ending HIV/AIDS by 2030 then, suggest and discuss new innovative ways of ending HIV scourge by 2030. Methods: Systematic literature review methodology was used to extract existing published information on HIV prevention strategies from 1981 to 2023. The articles were previewed by 2 experts for quality and grouped by intervention. Of the 637 articles accessed, on HIV prevention/control only 45 met the inclusion criteria. Data were synthesized using a narrative synthesis approach following standard guidelines on synthesis without meta-analysis. Descriptive analysis was done, strength and limitations were identified. UNAIDS recommendations for ending HIV/AIDS by 2030 identified and analyzed. New Innovations in HIV/AIDS were presented and discussed. The scope of the reviewed literature was limited to HIV preventive strategies practiced between 1981 and 2023. Results: Findings show that, Uganda’s HIV prevalence was at a peak in 1991 of 15% (30% among pregnant women in urban areas). ABC strategy is claimed to have turned sharply downward the prevalence through the mid-1990s and reached 5% (14% for pregnant urban women) by 2001. Analysis of the strategy showed that the achievements of the strategy could not be sustained, subsequently HIV prevalence rose again. This is because none of the ABC components can independently reduce HIV problem. In the real world, 100% abstinence has failed, condom use only reduces infection by 90% (WHO), and lifelong monogamy is impractical. Such limitations weaken ABC strategy. The study established that Post-exposure prophylaxis (PEP) i.e. taking HIV medicines within 72 hours (3 days) after a possible exposure to HIV infection is a safe, effective and a globally practiced HIV preventive intervention in emergency situations of HIV exposure. However, PEP is limited to care sought within 72 hours after exposure and yet timely access especially in rural areas and for key populations remains a big challenge. Oral PrEP was also identified as effective HIV preventive measure that can reduce HIV risk from sex by about 99% and from injection drug users by 74%. However, like PEP, timely access especially in rural areas and for key populations remains a big challenge. The UNAIDS 95-95-95 strategy (i.e. 95% of people know their HIV status, 95% with +HIV status be on sustained ART and 95% on ART get viral load suppression) formed the basis for setting the target of ending HIV/AIDS epidemic by 2030. However, our analysis shows that this target is unrealistic given the above highlighted limitations/ barriers in preventive measures and the unlikely perfect adherence (100%) to ART by all enrolled HIV positive persons. Conclusion: Ending HIV/AIDS by 2030 cannot be achieved by implementing the current preventing strategies and control measures. This study established that most of the existing HIV preventive strategies and control measures have a number of limitations. However, with sustained UN 95-95-95 strategy supplemented with additional innovative ways, there is hope that the UN dream of ending HIV/AIDS though not necessarily by 2030, can in the long run be achieved.展开更多
This paper presents generalized CAPP （G-CAPP） method which deals with macro process planning for multiobjective in the planning stage of production line of accuracy welding （PLAW） based on the features of accuracy...This paper presents generalized CAPP （G-CAPP） method which deals with macro process planning for multiobjective in the planning stage of production line of accuracy welding （PLAW） based on the features of accuracy welding production （ AWP ）. G-CAPP offers foundations for prototype design and general equipment sorting, production capacity predication and production analysis by means of simulation and optimization. A synthetic hierarchy evaluation （SHE） model for G-CAPP established according to the planning objective is utilized to estimate the alternate processing plans by using membership function and analytic hierarchy process （AHP） of operational theory. The assembly welding line of hydraulic torque converter （HTC） is as an example of typical A WP to explicate G-CAPP and synthetic evaluating strategy of PLAW. The feasible and rational process configuration strategies of HTC assembly welding line are pointed oat under different planning objective.展开更多
With the using of new full 3 - D interpretative technology, the carefully interpretation of the micro - amplitude structures and faults by the reprocessed 3 -D seismic data in IES (Interactive Exploration System) inte...With the using of new full 3 - D interpretative technology, the carefully interpretation of the micro - amplitude structures and faults by the reprocessed 3 -D seismic data in IES (Interactive Exploration System) interpretative system of Sun workstation is obtained. Because of the application of the well - advanced predictive technique for reservoir lithological changes, the predictive accuracy rate of drilling for 31 wells drilled in 1996 achieved 100 % and the economic and social benefits are desirable.展开更多
Background:Vitamin A deficiency is the main problem of public health worldwide demonstrated that 190 million population of preschool children and 122 countries(in Africa and South-East Asia)have vitamin A deficiency,a...Background:Vitamin A deficiency is the main problem of public health worldwide demonstrated that 190 million population of preschool children and 122 countries(in Africa and South-East Asia)have vitamin A deficiency,according to recent estimated research.In Afghanistan,vitamin A supplementation is a key strategy to prevent vitamin A deficiency among young children.Children receive vitamin A supplements as part of National Immunization Days(NID)campaigns.Methods:In this case study,the data was collected from June 15/2015 to February 23/2016,and the final report of the Afghanistan Demographic Health Survey(AfDHS)2015 was released on February 15/2017.All 27,209 children aged 6-59 months who are living with their mothers were included in this study.Who consumed foods rich in vitamin A was not included in this study.Results:The percentages who were given vitamin A supplements in the last 6 months among all children 6-59 months aged.A total of 1,572 children aged among 6-8 months were given vitamin A supplements 670(42.6%)children and comparison with the total community of the study(27,209)children(2.46%).A total of 1,148 children aged among 9-11 months were given vitamin A supplements to 465(40.5%)children and comparison with the total community of the study(27,209)children(1.70%).Conclusion:After following up on more studies,we found that vitamin A deficiency is a public problem,thus it is better to use wheat flour fortification,vitamin A capsule(VAC)supplementation,nutrition education,source of vitamin A,and training of primary healthcare workers on the clinical to prevent and treat the vitamin A deficiency among children.Therefore,we aimed to determine the given vitamin A supplementation among children aged 6-59 months in 33 provinces in Afghanistan,in 2015.展开更多
Ultra-narrow bandgap(ultra-NBG)small molecule acceptors(SMAs)show great potential in organic solar cells(OSCs)due to the extended near-infrared(NIR)absorption.In this work,a synergetic alkoxy side-chain and chlorine-c...Ultra-narrow bandgap(ultra-NBG)small molecule acceptors(SMAs)show great potential in organic solar cells(OSCs)due to the extended near-infrared(NIR)absorption.In this work,a synergetic alkoxy side-chain and chlorine-contained end group strategy is employed to achieve A-DA'D-A type ultra-NBG SMAs by introducing alkoxy chains with oxygen atom at the second position into the thiopheneβposition as well as replacing the F atoms with Cl atoms in the end group.As a result,the heptacyclic BZO-4F shows a redshifted absorption onset(960 nm)compared with Y11(932 nm)without oxygen atoms in the side chains.Then,the fluorinated end groups are substituted with the chlorinated ones to synthesize BZO-4Cl.The absorption onset of BZO-4Cl is further redshifted to 990 nm,corresponding to an optical ultra-NBG of 1.25 eV.When blending with the polymer donor PBDB-T,the binary devices based on PBDB-T:BZO-4F and PBDB-T:BZO-4Cl deliver power conversion efficiencies(PCEs)over 12%.Furthermore,ternary devices with the addition of BZ4F-O-1 into PBDB-T:BZO-4Cl system achieve the optimal PCE of 15.51%.This work proposes a synergetic alkoxy side-chain and chlorine-contained end group strategy to achieve A-DA'D-A type ultra-NBG SMAs,which is important for future molecular design.展开更多
The development of the higher education system in China has experienced huge changes alongside the transitions in the socio-economic milieu since the establishment of the People’s Republic of China in 1949.Among the ...The development of the higher education system in China has experienced huge changes alongside the transitions in the socio-economic milieu since the establishment of the People’s Republic of China in 1949.Among the major structural transformations of higher education,the reform during the 1950s and the one from 1998 to 2009 can be seen as two typical cases and manifestations of macro strategy modulation.Both reforms were driven by the need of strengthening and empowering the nation as a whole through the advancement of higher education.But the 1950s reforms featured the perpetuation of state control,highly centralized resource allocation,and authoritarian administration,while the 1998-2009 period reflected the transition from a planned to a market economy in higher education,manifested in an increased weight given to market forces,the enlarged autonomy of higher education institutions(HEIs)and expanded government guidance instead of mere state control.The paper will take the two periods as cases to show why and how the reforms were formulated and what directions they are leading towards.展开更多
文摘Binary wolf pack algorithm (BWPA) is a kind of intelligence algorithm which can solve combination optimization problems in discrete spaces.Based on BWPA, an improved binary wolf pack algorithm (AIBWPA) can be proposed by adopting adaptive step length and improved update strategy of wolf pack. AIBWPA is applied to 10 classic 0-1 knapsack problems and compared with BWPA, DPSO, which proves that AIBWPA has higher optimization accuracy and better computational robustness. AIBWPA makes the parameters simple, protects the population diversity and enhances the global convergence.
文摘Background: Globally, UNAIDS report 2022 shows, there are 84.2 million people affected by HIV/AIDS and 40.1 million deaths from AIDS since the start of epidemic. In sub-Saharan Africa, women and girls accounted for 63% of all new HIV infections in 2021 with, six in seven new HIV infections among adolescents aged 15 - 19 years being girls. Key populations accounted for 70% of HIV infections globally in 2021, with 51% of these new HIV infections in sub-Saharan Africa. Reflecting on the 4 decades’ journey of HIV epidemic amidst local, national and international efforts, the UN target of ending AIDS as a public health threat by 2030 remains questionable unless new innovative ways are used. This study aimed at analyzing existing HIV/AIDS interventions, discuss UN interventions in line with ending HIV/AIDS by 2030 then, suggest and discuss new innovative ways of ending HIV scourge by 2030. Methods: Systematic literature review methodology was used to extract existing published information on HIV prevention strategies from 1981 to 2023. The articles were previewed by 2 experts for quality and grouped by intervention. Of the 637 articles accessed, on HIV prevention/control only 45 met the inclusion criteria. Data were synthesized using a narrative synthesis approach following standard guidelines on synthesis without meta-analysis. Descriptive analysis was done, strength and limitations were identified. UNAIDS recommendations for ending HIV/AIDS by 2030 identified and analyzed. New Innovations in HIV/AIDS were presented and discussed. The scope of the reviewed literature was limited to HIV preventive strategies practiced between 1981 and 2023. Results: Findings show that, Uganda’s HIV prevalence was at a peak in 1991 of 15% (30% among pregnant women in urban areas). ABC strategy is claimed to have turned sharply downward the prevalence through the mid-1990s and reached 5% (14% for pregnant urban women) by 2001. Analysis of the strategy showed that the achievements of the strategy could not be sustained, subsequently HIV prevalence rose again. This is because none of the ABC components can independently reduce HIV problem. In the real world, 100% abstinence has failed, condom use only reduces infection by 90% (WHO), and lifelong monogamy is impractical. Such limitations weaken ABC strategy. The study established that Post-exposure prophylaxis (PEP) i.e. taking HIV medicines within 72 hours (3 days) after a possible exposure to HIV infection is a safe, effective and a globally practiced HIV preventive intervention in emergency situations of HIV exposure. However, PEP is limited to care sought within 72 hours after exposure and yet timely access especially in rural areas and for key populations remains a big challenge. Oral PrEP was also identified as effective HIV preventive measure that can reduce HIV risk from sex by about 99% and from injection drug users by 74%. However, like PEP, timely access especially in rural areas and for key populations remains a big challenge. The UNAIDS 95-95-95 strategy (i.e. 95% of people know their HIV status, 95% with +HIV status be on sustained ART and 95% on ART get viral load suppression) formed the basis for setting the target of ending HIV/AIDS epidemic by 2030. However, our analysis shows that this target is unrealistic given the above highlighted limitations/ barriers in preventive measures and the unlikely perfect adherence (100%) to ART by all enrolled HIV positive persons. Conclusion: Ending HIV/AIDS by 2030 cannot be achieved by implementing the current preventing strategies and control measures. This study established that most of the existing HIV preventive strategies and control measures have a number of limitations. However, with sustained UN 95-95-95 strategy supplemented with additional innovative ways, there is hope that the UN dream of ending HIV/AIDS though not necessarily by 2030, can in the long run be achieved.
文摘This paper presents generalized CAPP （G-CAPP） method which deals with macro process planning for multiobjective in the planning stage of production line of accuracy welding （PLAW） based on the features of accuracy welding production （ AWP ）. G-CAPP offers foundations for prototype design and general equipment sorting, production capacity predication and production analysis by means of simulation and optimization. A synthetic hierarchy evaluation （SHE） model for G-CAPP established according to the planning objective is utilized to estimate the alternate processing plans by using membership function and analytic hierarchy process （AHP） of operational theory. The assembly welding line of hydraulic torque converter （HTC） is as an example of typical A WP to explicate G-CAPP and synthetic evaluating strategy of PLAW. The feasible and rational process configuration strategies of HTC assembly welding line are pointed oat under different planning objective.
文摘With the using of new full 3 - D interpretative technology, the carefully interpretation of the micro - amplitude structures and faults by the reprocessed 3 -D seismic data in IES (Interactive Exploration System) interpretative system of Sun workstation is obtained. Because of the application of the well - advanced predictive technique for reservoir lithological changes, the predictive accuracy rate of drilling for 31 wells drilled in 1996 achieved 100 % and the economic and social benefits are desirable.
文摘Background:Vitamin A deficiency is the main problem of public health worldwide demonstrated that 190 million population of preschool children and 122 countries(in Africa and South-East Asia)have vitamin A deficiency,according to recent estimated research.In Afghanistan,vitamin A supplementation is a key strategy to prevent vitamin A deficiency among young children.Children receive vitamin A supplements as part of National Immunization Days(NID)campaigns.Methods:In this case study,the data was collected from June 15/2015 to February 23/2016,and the final report of the Afghanistan Demographic Health Survey(AfDHS)2015 was released on February 15/2017.All 27,209 children aged 6-59 months who are living with their mothers were included in this study.Who consumed foods rich in vitamin A was not included in this study.Results:The percentages who were given vitamin A supplements in the last 6 months among all children 6-59 months aged.A total of 1,572 children aged among 6-8 months were given vitamin A supplements 670(42.6%)children and comparison with the total community of the study(27,209)children(2.46%).A total of 1,148 children aged among 9-11 months were given vitamin A supplements to 465(40.5%)children and comparison with the total community of the study(27,209)children(1.70%).Conclusion:After following up on more studies,we found that vitamin A deficiency is a public problem,thus it is better to use wheat flour fortification,vitamin A capsule(VAC)supplementation,nutrition education,source of vitamin A,and training of primary healthcare workers on the clinical to prevent and treat the vitamin A deficiency among children.Therefore,we aimed to determine the given vitamin A supplementation among children aged 6-59 months in 33 provinces in Afghanistan,in 2015.
基金This work was supported by the National Natural Science Foundation of China(Nos.52125306,22005347).
文摘Ultra-narrow bandgap(ultra-NBG)small molecule acceptors(SMAs)show great potential in organic solar cells(OSCs)due to the extended near-infrared(NIR)absorption.In this work,a synergetic alkoxy side-chain and chlorine-contained end group strategy is employed to achieve A-DA'D-A type ultra-NBG SMAs by introducing alkoxy chains with oxygen atom at the second position into the thiopheneβposition as well as replacing the F atoms with Cl atoms in the end group.As a result,the heptacyclic BZO-4F shows a redshifted absorption onset(960 nm)compared with Y11(932 nm)without oxygen atoms in the side chains.Then,the fluorinated end groups are substituted with the chlorinated ones to synthesize BZO-4Cl.The absorption onset of BZO-4Cl is further redshifted to 990 nm,corresponding to an optical ultra-NBG of 1.25 eV.When blending with the polymer donor PBDB-T,the binary devices based on PBDB-T:BZO-4F and PBDB-T:BZO-4Cl deliver power conversion efficiencies(PCEs)over 12%.Furthermore,ternary devices with the addition of BZ4F-O-1 into PBDB-T:BZO-4Cl system achieve the optimal PCE of 15.51%.This work proposes a synergetic alkoxy side-chain and chlorine-contained end group strategy to achieve A-DA'D-A type ultra-NBG SMAs,which is important for future molecular design.
文摘The development of the higher education system in China has experienced huge changes alongside the transitions in the socio-economic milieu since the establishment of the People’s Republic of China in 1949.Among the major structural transformations of higher education,the reform during the 1950s and the one from 1998 to 2009 can be seen as two typical cases and manifestations of macro strategy modulation.Both reforms were driven by the need of strengthening and empowering the nation as a whole through the advancement of higher education.But the 1950s reforms featured the perpetuation of state control,highly centralized resource allocation,and authoritarian administration,while the 1998-2009 period reflected the transition from a planned to a market economy in higher education,manifested in an increased weight given to market forces,the enlarged autonomy of higher education institutions(HEIs)and expanded government guidance instead of mere state control.The paper will take the two periods as cases to show why and how the reforms were formulated and what directions they are leading towards.
