AIM: To investigate the characteristics of postoperative central visual field defect(cVFD) in patients with macular hole(MH).METHODS: Eighteen eyes from 18 MH patients were involved in this retrospective study which r...AIM: To investigate the characteristics of postoperative central visual field defect(cVFD) in patients with macular hole(MH).METHODS: Eighteen eyes from 18 MH patients were involved in this retrospective study which reviewed square root of loss variance(sLV) and mean defect(MD) of the visual field test in all subjects. The relationship between cVFD and MH stage, as well as the postoperative ellipsoid zone disruption were evaluated using Spearman's correlation test. RESULTS: Our analysis determined Spearman coefficient is 0.705 for the correlation between sLV and MH stage(P<0.01), 0.877 for the correlation between sLV and postoperative ellipsoid zone disruption(P<0.01) and 0.721 for the correlation between MD and postoperative ellipsoid zone disruption(P<0.01). A significant relationship was also detected between postoperative ellipsoid zone disruption and MH stage(r=0.470, P<0.05). Univariate regression analysis indicated that sLV and MD were associated with postoperative ellipsoid zone disruption(P<0.01, P<0.01, respectively). CONCLUSION: Postoperative cVFD is highly correlated with MH stage and postoperative ellipsoid zone disruption in patients with MH.展开更多
AIM: To explore an improved procedure involving incomplete fluid-air exchange for idiopathic macular hole(IMH), and the closure rate, visual function, and the visual field of macular holes(MHs) were evaluated.METHODS:...AIM: To explore an improved procedure involving incomplete fluid-air exchange for idiopathic macular hole(IMH), and the closure rate, visual function, and the visual field of macular holes(MHs) were evaluated.METHODS: This prospective randomized controlled study, included 40 eyes of 40 patients with IMH who were treated with pars plana vitrectomy and peeling of the internal limiting membrane. They were grouped by random digital table. Twenty-one eyes underwent incomplete fluidair exchange(IFA) and 19 eyes underwent traditional complete fluid-air exchange(CFA) as the control group. Outcomes included best-corrected visual acuity(BCVA), intraocular pressure, and optical coherence tomography, light adaptive electroretinography, and visual field evaluations.RESULTS: All MHs <400 μm were successfully closed. BCVAs before and 6 mo after surgery were 0.82±0.41 logMAR and 0.28±0.17 logMAR in IFA group and 0.86±0.34 logMAR and 0.34±0.23 logMAR in CFA group, respectively. The electroretinogram analysis of patients in IFA group revealed increases in b-wave amplitudes at 1, 3, and 6 mo after surgery. Additionally, patients in IFA group showed an amplitude increase of 28.6% from baseline at 6 mo(P<0.05), while no obvious improvements were noted in CFA group. Although there were no statistically significant improvements in either group, the IFA group showed a slight increase in mean sensitivity(P>0.05).CONCLUSION: IFA is a reliable method that offers comparable closure rate to CFA and facilitates improvements in visual function.展开更多
<strong>Background:</strong><span "=""> Macular hole is a known cause of central visual defect with varying etiologies in different parts of the world. It was considered an untreatable...<strong>Background:</strong><span "=""> Macular hole is a known cause of central visual defect with varying etiologies in different parts of the world. It was considered an untreatable condition until 1991 when varying treatment techniques began to emerge with resultant restoration of central vision. This study was carried out to evaluate the prevalence and pattern of Macular hole in a tertiary eye centre in Nigeria. <b>Method:</b> This is a prospective hospital</span>-<span "="">based study over a 5 year period spanning from November 2013 to October 2018. All patients with macular hole seen within this period were included in the study. Relevant data were recorded with a structured questionnaire and analysed with SPSS version 20. <b>Results:</b> There were 46 eyes of 42 patients which constituted about 0.5% of all new patients seen over the study period. Male to female ratio was 1:1.3 with age ranged between 15 and 91years (mean</span><span "=""> </span>=<span "=""> </span>61.8<span "=""> </span>±<span "=""> </span>16.5<span "=""> </span>years). The majority of <span "="">the patients (95.7%) had Idiopathic macular hole. Half of the patients (54.8%) had visual acuity less than 3/60 in the affected eye at the time of presentation. The majority (95.7%) of the patients did not accept the recommended surgical treatment option because of financial incapacitation. <b>Conclusion:</b> Macular hole is a disease of marked visual consequence. Available treatment option is still not within the reach of the majority because of the high cost.展开更多
基金Supported by National Natural Science Foundation of China(No.81670865 No.81500743)Natural Science Foundation of Tianjin(No.16JCQNJC13000)
文摘AIM: To investigate the characteristics of postoperative central visual field defect(cVFD) in patients with macular hole(MH).METHODS: Eighteen eyes from 18 MH patients were involved in this retrospective study which reviewed square root of loss variance(sLV) and mean defect(MD) of the visual field test in all subjects. The relationship between cVFD and MH stage, as well as the postoperative ellipsoid zone disruption were evaluated using Spearman's correlation test. RESULTS: Our analysis determined Spearman coefficient is 0.705 for the correlation between sLV and MH stage(P<0.01), 0.877 for the correlation between sLV and postoperative ellipsoid zone disruption(P<0.01) and 0.721 for the correlation between MD and postoperative ellipsoid zone disruption(P<0.01). A significant relationship was also detected between postoperative ellipsoid zone disruption and MH stage(r=0.470, P<0.05). Univariate regression analysis indicated that sLV and MD were associated with postoperative ellipsoid zone disruption(P<0.01, P<0.01, respectively). CONCLUSION: Postoperative cVFD is highly correlated with MH stage and postoperative ellipsoid zone disruption in patients with MH.
基金Supported by National Natural Science Foundation of Xinjiang Autonomous Region, China (No.81460089)
文摘AIM: To explore an improved procedure involving incomplete fluid-air exchange for idiopathic macular hole(IMH), and the closure rate, visual function, and the visual field of macular holes(MHs) were evaluated.METHODS: This prospective randomized controlled study, included 40 eyes of 40 patients with IMH who were treated with pars plana vitrectomy and peeling of the internal limiting membrane. They were grouped by random digital table. Twenty-one eyes underwent incomplete fluidair exchange(IFA) and 19 eyes underwent traditional complete fluid-air exchange(CFA) as the control group. Outcomes included best-corrected visual acuity(BCVA), intraocular pressure, and optical coherence tomography, light adaptive electroretinography, and visual field evaluations.RESULTS: All MHs <400 μm were successfully closed. BCVAs before and 6 mo after surgery were 0.82±0.41 logMAR and 0.28±0.17 logMAR in IFA group and 0.86±0.34 logMAR and 0.34±0.23 logMAR in CFA group, respectively. The electroretinogram analysis of patients in IFA group revealed increases in b-wave amplitudes at 1, 3, and 6 mo after surgery. Additionally, patients in IFA group showed an amplitude increase of 28.6% from baseline at 6 mo(P<0.05), while no obvious improvements were noted in CFA group. Although there were no statistically significant improvements in either group, the IFA group showed a slight increase in mean sensitivity(P>0.05).CONCLUSION: IFA is a reliable method that offers comparable closure rate to CFA and facilitates improvements in visual function.
文摘<strong>Background:</strong><span "=""> Macular hole is a known cause of central visual defect with varying etiologies in different parts of the world. It was considered an untreatable condition until 1991 when varying treatment techniques began to emerge with resultant restoration of central vision. This study was carried out to evaluate the prevalence and pattern of Macular hole in a tertiary eye centre in Nigeria. <b>Method:</b> This is a prospective hospital</span>-<span "="">based study over a 5 year period spanning from November 2013 to October 2018. All patients with macular hole seen within this period were included in the study. Relevant data were recorded with a structured questionnaire and analysed with SPSS version 20. <b>Results:</b> There were 46 eyes of 42 patients which constituted about 0.5% of all new patients seen over the study period. Male to female ratio was 1:1.3 with age ranged between 15 and 91years (mean</span><span "=""> </span>=<span "=""> </span>61.8<span "=""> </span>±<span "=""> </span>16.5<span "=""> </span>years). The majority of <span "="">the patients (95.7%) had Idiopathic macular hole. Half of the patients (54.8%) had visual acuity less than 3/60 in the affected eye at the time of presentation. The majority (95.7%) of the patients did not accept the recommended surgical treatment option because of financial incapacitation. <b>Conclusion:</b> Macular hole is a disease of marked visual consequence. Available treatment option is still not within the reach of the majority because of the high cost.
