The current studies describing magnetic stimulation for treatment of nervous system diseases mainly focus on transcranial magnetic stimulation and rarely focus on spinal cord magnetic stimulation. Spinal cord magnetic...The current studies describing magnetic stimulation for treatment of nervous system diseases mainly focus on transcranial magnetic stimulation and rarely focus on spinal cord magnetic stimulation. Spinal cord magnetic stimulation has been confirmed to promote neural plasticity after injuries of spinal cord, brain and peripheral nerve. To evaluate the effects of impulse magnetic stimulation of the spinal cord on peripheral nerve regneration, we compressed a 3 mm segment located in the middle third of the hip using a sterilized artery forceps to induce ischemia. Then, all animals underwent impulse magnetic stimulation of the lumbar portion of spinal crod and spinal nerve roots daily for 1 month. Electron microscopy results showed that in and below the injuryed segment, the inflammation and demyelination of neural tissue were alleviated, apoptotic cells were reduced, and injured Schwann cells and myelin fibers were repaired. These findings suggest that high-frequency impulse magnetic stimulation of spinal cord and corresponding spinal nerve roots promotes synaptic regeneration following sciatic nerve injury.展开更多
In order to study the multi-field coupling mechanical behavior of the simply-supported conductive rectangular thin plate under the condition of an externally lateral strong impulsive magnetic field, that is the dynami...In order to study the multi-field coupling mechanical behavior of the simply-supported conductive rectangular thin plate under the condition of an externally lateral strong impulsive magnetic field, that is the dynamic buckling phenomenon of the thin plates in the effect of the magnetic volume forces produced by the interaction between the eddy current and the magnetic fields, a FEM analysis program is developed to characterize the phenomena of magnetoelastic buckling and instability of the plates. The critical values of magnetic field for the three different initial vibrating modes are obtained, with a detailed discussion made on the effects of the lengththickness ratio a/h of the plate and the length-width ratio a/b as well as the impulse parameter on the critical value BOcr of the applied magnetic field.展开更多
Objective: To observe the impacts of electro-acupuncture(EA) and psychological intervention(PI) on impulsive behavior among internet addiction(IA) adolescents. Methods: Thirty-two IA adolescents were allocated...Objective: To observe the impacts of electro-acupuncture(EA) and psychological intervention(PI) on impulsive behavior among internet addiction(IA) adolescents. Methods: Thirty-two IA adolescents were allocated to either EA(16 cases) or PI(16 cases) group by a randomized digital table. Subjects in the EA group received EA treatment and subjects in the PI group received cognition and behavior therapy. All adolescents underwent 45-d intervention. Sixteen healthy volunteers were recruited into a control group. Barratt Impulsiveness Scale(BIS-11) scores, Young's Internet Addiction Test(IAT) as well as the ratio of brain N-acetyl aspartate(NAA) to creatine(NAA/Cr) and choline(Cho) to creatine(Cho/Cr) were recorded by magnetic resonance spectroscopy before and after intervention respectively. Results: The IAT scores and BIS-11 total scores in both EA and PI group were remarkably decreased after treatment(P〈0.05), while EA group showed more significant decrease in certain BIS-11 sub-factors(P〈0.05). Both NAA/Cr and Cho/Cr were significantly improved in EA group after treatment(P〈0.05); however, there were no significant changes of NAA/Cr or Cho/Cr in PI group after treatment(P〉0.05). Conclusions: Both EA and PI had significantly positive effect on IA adolescents, especially in the aspects of psychological experiences and behavioral expressions, EA might have an advantage over PI in terms of impulsivity control and brain neuron protection. The mechanism underlying this advantage might be related to the increased NAA and Cho levels in prefrontal and anterior cingulate cortices.展开更多
文摘The current studies describing magnetic stimulation for treatment of nervous system diseases mainly focus on transcranial magnetic stimulation and rarely focus on spinal cord magnetic stimulation. Spinal cord magnetic stimulation has been confirmed to promote neural plasticity after injuries of spinal cord, brain and peripheral nerve. To evaluate the effects of impulse magnetic stimulation of the spinal cord on peripheral nerve regneration, we compressed a 3 mm segment located in the middle third of the hip using a sterilized artery forceps to induce ischemia. Then, all animals underwent impulse magnetic stimulation of the lumbar portion of spinal crod and spinal nerve roots daily for 1 month. Electron microscopy results showed that in and below the injuryed segment, the inflammation and demyelination of neural tissue were alleviated, apoptotic cells were reduced, and injured Schwann cells and myelin fibers were repaired. These findings suggest that high-frequency impulse magnetic stimulation of spinal cord and corresponding spinal nerve roots promotes synaptic regeneration following sciatic nerve injury.
基金Project supported by the National Natural Sciences Foundation of China (Nos. 10132010 and 90405005).
文摘In order to study the multi-field coupling mechanical behavior of the simply-supported conductive rectangular thin plate under the condition of an externally lateral strong impulsive magnetic field, that is the dynamic buckling phenomenon of the thin plates in the effect of the magnetic volume forces produced by the interaction between the eddy current and the magnetic fields, a FEM analysis program is developed to characterize the phenomena of magnetoelastic buckling and instability of the plates. The critical values of magnetic field for the three different initial vibrating modes are obtained, with a detailed discussion made on the effects of the lengththickness ratio a/h of the plate and the length-width ratio a/b as well as the impulse parameter on the critical value BOcr of the applied magnetic field.
基金Supported by the National Natural Science Foundation of China(No.81072852,No.81574047)The Training Funds of Academic and Technical Leader in Sichuan Province+1 种基金Fok Ying-dong Education Foundation on Basic Research Project(No.131106)People-Benefiting Technology Research and Development Project of Chengdu Science and Technology Bureau(No.2014-HM01-00180-SF)
文摘Objective: To observe the impacts of electro-acupuncture(EA) and psychological intervention(PI) on impulsive behavior among internet addiction(IA) adolescents. Methods: Thirty-two IA adolescents were allocated to either EA(16 cases) or PI(16 cases) group by a randomized digital table. Subjects in the EA group received EA treatment and subjects in the PI group received cognition and behavior therapy. All adolescents underwent 45-d intervention. Sixteen healthy volunteers were recruited into a control group. Barratt Impulsiveness Scale(BIS-11) scores, Young's Internet Addiction Test(IAT) as well as the ratio of brain N-acetyl aspartate(NAA) to creatine(NAA/Cr) and choline(Cho) to creatine(Cho/Cr) were recorded by magnetic resonance spectroscopy before and after intervention respectively. Results: The IAT scores and BIS-11 total scores in both EA and PI group were remarkably decreased after treatment(P〈0.05), while EA group showed more significant decrease in certain BIS-11 sub-factors(P〈0.05). Both NAA/Cr and Cho/Cr were significantly improved in EA group after treatment(P〈0.05); however, there were no significant changes of NAA/Cr or Cho/Cr in PI group after treatment(P〉0.05). Conclusions: Both EA and PI had significantly positive effect on IA adolescents, especially in the aspects of psychological experiences and behavioral expressions, EA might have an advantage over PI in terms of impulsivity control and brain neuron protection. The mechanism underlying this advantage might be related to the increased NAA and Cho levels in prefrontal and anterior cingulate cortices.