The finding of giant magnetoresistive（GMR） effect develops a new field for the sensing application with magnetic nanoparticles（MNPs） labeling. A convenient GMR sensor was built with a permanent magnet to excite th...The finding of giant magnetoresistive（GMR） effect develops a new field for the sensing application with magnetic nanoparticles（MNPs） labeling. A convenient GMR sensor was built with a permanent magnet to excite the MNPs in this work. The sensing element contained a Wheatstone bridge with the GMR material as one of its branches. The magnetic field from MNPs unbalanced the Wheatstone bridge. After being amplified, the output signals were recorded. The construction and optimization of the magnetoresistive sensing platform were discussed in detail. The detection of three kinds of MNPs validated the performance of the proposed GMR sensor. The sensor showed a fast response to the addition or removal of MNPs. Because of its simplicity, this kind of GMR sensor can be developed in a routine laboratory. The finding of this new GMR sensor will promote the development of the method of probing biomoleeules and the study on the biomolecular interaction after being labeled magnetically.展开更多
Magnetic sensors based on tunneling magnetoresistance(TMR)effect exhibit high sensitivity,small size,and low power consumption.They have gained a lot of attention and have potential applications in various domains.Thi...Magnetic sensors based on tunneling magnetoresistance(TMR)effect exhibit high sensitivity,small size,and low power consumption.They have gained a lot of attention and have potential applications in various domains.This study first introduces the development history and basic principles of TMR sensors.Then,a comprehensive description of TMR sensors linearization and Wheatstone bridge configuration is presented.Two key performance parameters,the field sensitivity and noise mechanisms,are considered.Finally,the emerging applications of TMR sensors are discussed.展开更多
基金Supported by the National Basic Research Program of China（No.2011CB707703）, the National Natural Science Foundation of China（Nos.21375064, 21075068） and the Fundamental Research Funds for the Central Universities of China（No.20130031110016）.
文摘The finding of giant magnetoresistive（GMR） effect develops a new field for the sensing application with magnetic nanoparticles（MNPs） labeling. A convenient GMR sensor was built with a permanent magnet to excite the MNPs in this work. The sensing element contained a Wheatstone bridge with the GMR material as one of its branches. The magnetic field from MNPs unbalanced the Wheatstone bridge. After being amplified, the output signals were recorded. The construction and optimization of the magnetoresistive sensing platform were discussed in detail. The detection of three kinds of MNPs validated the performance of the proposed GMR sensor. The sensor showed a fast response to the addition or removal of MNPs. Because of its simplicity, this kind of GMR sensor can be developed in a routine laboratory. The finding of this new GMR sensor will promote the development of the method of probing biomoleeules and the study on the biomolecular interaction after being labeled magnetically.
基金financially supported by Beijing Municipal Science and Technology Project(No.Z201100004220002)the International Collaboration Project B16001+1 种基金the Key Research and Development Program of Shandong Province of China(No.2020S020201-01621)the Magnetic Sensor Innovation Platform from Laoshan District。
文摘Magnetic sensors based on tunneling magnetoresistance(TMR)effect exhibit high sensitivity,small size,and low power consumption.They have gained a lot of attention and have potential applications in various domains.This study first introduces the development history and basic principles of TMR sensors.Then,a comprehensive description of TMR sensors linearization and Wheatstone bridge configuration is presented.Two key performance parameters,the field sensitivity and noise mechanisms,are considered.Finally,the emerging applications of TMR sensors are discussed.
