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Discourse Analysis of the Belt and Road Initiative From the Perspective of Central Asian Countries: A Case Study of the Republic of Kazakhstan
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作者 CHEN Jia LIU Shumin +1 位作者 FU Da’an SHAO Di 《Journalism and Mass Communication》 2024年第2期96-100,共5页
This study employs Norman Fairclough’s Critical Discourse Analysis(CDA)three-dimensional model,using the Republic of Kazakhstan as a case study,to delve into the discourse construction of China’s Belt and Road Initi... This study employs Norman Fairclough’s Critical Discourse Analysis(CDA)three-dimensional model,using the Republic of Kazakhstan as a case study,to delve into the discourse construction of China’s Belt and Road Initiative(BRI)in Central Asian countries.Through detailed analysis of policy documents,media reports,and public discussions in Central Asian countries,this paper reveals how the BRI constructs specific social practices,discourse events,and textual meanings within these nations.The findings indicate that through this global development strategy,China has not only strengthened its economic ties with Central Asian countries but has also exerted profound influences on political,cultural,and social levels. 展开更多
关键词 Belt and Road initiative Central Asian countries discourse analysis Norman Fairclough’s three-dimensional model
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Patterns of medication use for the treatment of menopausal symptoms before and after the women’s health initiative;implications for decision-making practices of women and women’s health professionals 被引量:2
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作者 Chioma Uzoigwe Smith Srini Rajagopalan +3 位作者 Shiva Sajjan Shuvayu Sankar Sen Wenchen Kenneth Wu Henry Hu 《Health》 2011年第7期416-422,共7页
Background: The Women’s Health Initiative (WHI) published findings in 2002 that changed the perception of the use of hormone replacement therapy (HRT) for the reduction of cardiovascular risks. Menopausal women using... Background: The Women’s Health Initiative (WHI) published findings in 2002 that changed the perception of the use of hormone replacement therapy (HRT) for the reduction of cardiovascular risks. Menopausal women using HRT for the relief of vasomotor symptoms were advised to use the lowest possible dose of HRT over the shortest possible duration. Objective: This study sought to examine patterns of HRT use for the treatment of menopausal symptoms before and after the WHI among women at least 40 years of age. Methods: A retrospective analysis was performed on a total of 1367 women in the pre-WHI group and 6467 women in the post-WHI group using the U.S. General Electric (GE) Centricity electronic medical record database. Menopause diagnosis was assessed using ICD-9 codes. Clinical characteristics and medication use were assessed for women with at least 3 years of enrollment (1 year baseline, 2 years follow-up). Results: The proportion of women in the post-WHI group that initiated HRT was significantly less than that of women in the pre-WHI group (31.3% vs. 56.9%, respectively;p < 0.001). Combination HRT use declined significantly (21.9% pre-WHI cohort vs. 7.2% post- WHI cohort, p < 0.001) among increases in non-HRT use, namely SSRIs (15.2% pre-WHI cohort v. 22.3% post-WHI cohort, p < 0.001) and tranquilizers (9.5% pre-WHI cohort v. 15.8% post-WHI cohort, p < 0.001). Conclusion: The results of the WHI 2002 publication made an impression on the perception of HRT’s role in the relief of menopausal symptoms. Decision-making on the part of women seeking treatment for vasomotor symptoms and women’s health professionals demonstrates that despite HRT precautions, women continue to exhibit a need for HRT use. This study’s findings suggest that women seeking treatment for menopausal symptom relief and women’s health professionals continue to work together to find the appropriate balance between therapy use and adherence to therapy use guidelines. 展开更多
关键词 Women’s HEALtH initiative (WHI) HORMONE Replacement therapy (HRt) Women’s HEALtH MENOPAUsE
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The"Belt and Road"Initiative:A Chinese Concept for Global Development 被引量:1
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作者 Tian Wenlin 《Contemporary International Relations》 2017年第4期1-20,共20页
China's "Belt and Road" initiative is emerging as the Western-dominated world order is declining. Capitalism has intensified the rich-poor divide and power politics have led to great upheavals. Western values have ... China's "Belt and Road" initiative is emerging as the Western-dominated world order is declining. Capitalism has intensified the rich-poor divide and power politics have led to great upheavals. Western values have caused a "value dislocation" for non-Western countries. The world is calling for new development concepts. The "Belt and Road" initiative has emerged as an answer. It embodies China's ideas on global development. First, it works for the "common prosperity" of every country, which will ease contradictions between the South and the North. Second, it emphasizes geo-economie integration that will heal the fragmentation of Eurasia. Third, it advocates linkages between people and inclusiveness to create a new kind of civilization. However, many difficulties and challenges lie ahead for the implementation of the "Belt and Road" initiative. 展开更多
关键词 Belt and Road initiative global development geopolitical integration China' s conception
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Australia’s Fear and Greed over China’s Rise:A Discourse Analysis of Mainstream News Coverage of the Belt and Road Initiative
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作者 CHEN Zhixin 《International Relations and Diplomacy》 2018年第8期436-448,共13页
China’s rise has stirred up world-wide debate.In Australia,China has been one of the keywords in its foreign and strategic policies and on news media.Its rise intensifies the dual functions―benefit provider and secu... China’s rise has stirred up world-wide debate.In Australia,China has been one of the keywords in its foreign and strategic policies and on news media.Its rise intensifies the dual functions―benefit provider and security offender to Australia and the tensions between greed of economic gains and fear of China’s increasing geopolitical strength and influence.The“fear and greed”narration is well-presented on Australian mainstream media.Such ambivalence can also find its expressions in the recent typical case of China’s rise―the Belt and Road Initiative.It is worthwhile to find out how Australia’s ambivalence to BRI and China’s rise is represented on media and to draw the sociopolitical inferences behind“fear and greed”.The thesis is going to take BRI as a typical example of China’s rise to examine the ambivalent“fear and greed”narration on Australian mainstream news media.Data sample includes news reports of BRI from ABC News,The Australian,The Australian Financial Review,The Sydney Morning Herald,and The Age from September 1st,2013 to October 31st,2017.The discourse analysis on China’s images finds that Australia is rather biased against China,regarding China both as a lucrative friend and a threatening enemy.The bias lingers on for centuries and generates misunderstanding,mistrust,and anxiety.Profit drives Australia to establish closer economic ties with China,while value differences would not allow too much proximity but help to maintain a robust alliance with its allies.Australia’s position between its major economic partner and traditional allies has caused much concern and will have a long-term influence on its policy-making decisions. 展开更多
关键词 China’s RIsE BELt and Road initiative(BRI) FEAR and GREED
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The Belt and Road Initiatives and China's Middle East Energy Policy
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作者 Xuming Qian 《International Relations and Diplomacy》 2016年第10期611-616,共6页
The paper analyses the roots of the Belt and Road Initiative as well as China's Middle East Energy Policy in an age of great transformation. China's rapidly progressed economic growth leading to a dramatic increase ... The paper analyses the roots of the Belt and Road Initiative as well as China's Middle East Energy Policy in an age of great transformation. China's rapidly progressed economic growth leading to a dramatic increase in China's energy demand in recent years. The Middle East countries play a critical role in the international energy markets. Stable relations with the Middle East countries become increasingly important for Chinese energy security, and the continued development. The protection of these relations lies at the core of the Belt and Road Initiative. Within The Belt and Road Initiative, Chinese Middle East energy policy proceeds according to the energy cooperation framework known as "1+2+3", which seeks to build a reliable China-Arab strategic cooperative relationship based on long-term friendship. To avoid over dependence on the energy resources of the Middle East, China will also continue to search for other overseas energy sources and protect transportation channels. Despite risks and challenges associated with energy imports from the Middle East, China has cultivated strong relations with states in the region and will develop these economic ties further in the coming years. 展开更多
关键词 the Belt and Road initiative Middle East China's foreign policy China-Arab relations
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The Belt and Road Initiatives and China's International Energy Cooperation: Progress, Mechanisms, and Recommendations
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作者 Qian Xu-ming 《Cultural and Religious Studies》 2017年第2期85-94,共10页
China's international energy cooperation and energy security are important parts of The Belt and Road initiatives. China and the countries along the Belt and Road continue to promote cooperation, actively use the exi... China's international energy cooperation and energy security are important parts of The Belt and Road initiatives. China and the countries along the Belt and Road continue to promote cooperation, actively use the existing bilateral and multilateral cooperation mechanisms to promote the regional and inter-regional energy cooperation. Countries along the Belt and Road are rich in oil and gas resources; their demand on the diversification of export meet with the diversification demand on imports of consumption countries; and their oil refining and chemical technology as well as construction capacity is weak, which provides a lot of new opportunities in cooperation for Chinese enterprises. However, the energy cooperation of Chinese enterprises are also facing some challenges in the complex environment of energy cooperation, the interference of big powers, non-traditional security threats, and energy policy factors. Finally, the paper puts forward the strategic thinking of China's international energy cooperation under the new situation. 展开更多
关键词 the Belt and Road initiatives China's international energy cooperation energy cooperation mechanism energy strategic channels
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粗穗披碱草1H^(t)S染色体特异荧光原位杂交标记开发
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作者 宫文萍 汪晓璐 +6 位作者 王开 韩冉 祁广 徐文竞 曾小雪 郭军 刘成 《山东农业科学》 北大核心 2024年第7期16-22,共7页
小麦-粗穗披碱草1H^(t)S.1BL罗伯逊易位系高抗小麦条锈病和叶锈病,是小麦遗传改良的优异基因源。我们前期利用中国春ph1b基因突变体对该易位系进行诱导,获得了一批诱导后代材料,为了从中准确鉴定小麦-粗穗披碱草1H^(t)S小片段易位系,需... 小麦-粗穗披碱草1H^(t)S.1BL罗伯逊易位系高抗小麦条锈病和叶锈病,是小麦遗传改良的优异基因源。我们前期利用中国春ph1b基因突变体对该易位系进行诱导,获得了一批诱导后代材料,为了从中准确鉴定小麦-粗穗披碱草1H^(t)S小片段易位系,需要建立能够覆盖粗穗披碱草1H^(t)S染色体的荧光原位杂交(FISH)标记。本研究利用21个小麦及其近缘种探针、61个基于中国春基因组序列新开发的小麦1BS染色体探针以及40个根据简单三碱基重复序列新开发的探针对小麦-粗穗披碱草1H^(t)S.1BL易位系进行非变性FISH分析。结果显示,B74、B76和B77等36个探针(33个为新开发的)在1H^(t)S染色体上具有杂交信号,并且杂交信号可分为仅在染色体末端、仅在着丝粒处、同时在着丝粒处和近着丝粒处、覆盖1H^(t)S约3/4染色体臂、覆盖绝大部分1H^(t)S共五种类型。因此,部分探针单独使用或多个探针联合使用,其信号能覆盖1H^(t)S染色体,能够满足小麦-粗穗披碱草1H^(t)S小片段易位系鉴定,这可为小麦背景中粗穗披碱草染色质追踪提供新的检测手段。 展开更多
关键词 粗穗披碱草 1H^(t)s染色体 探针 荧光原位杂交标记
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基于量子衍生涡流算法和T⁃S模糊推理模型的储层岩性识别
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作者 赵娅 管玉 +1 位作者 李盼池 王伟 《石油地球物理勘探》 EI CSCD 北大核心 2024年第1期23-30,共8页
鉴于梯度下降法易陷入局部极值、普通群智能优化算法易早熟收敛,提出一种基于量子衍生涡流算法(Quantum Vortex Search Algorithm,QVSA)和T⁃S模糊推理模型的岩性识别方法,QVSA具有操作简单、收敛速度快、寻优能力强等优点,有助于T⁃S模... 鉴于梯度下降法易陷入局部极值、普通群智能优化算法易早熟收敛,提出一种基于量子衍生涡流算法(Quantum Vortex Search Algorithm,QVSA)和T⁃S模糊推理模型的岩性识别方法,QVSA具有操作简单、收敛速度快、寻优能力强等优点,有助于T⁃S模糊推理模型获得最优参数配置,从而实现储层岩性的准确识别。首先利用具有全局搜索能力的QVSA优化T⁃S模糊推理模型的各种参数;然后利用主成分分析方法降低获取的地震属性维度;再利用优化的T⁃S模糊推理模型识别储层岩性。实验结果表明,利用反映储层特征的8个地震属性识别储层岩性时,所提方法的识别正确率达到92%,比普通BP网络方法高5.1%,同时查准率、查全率、F1分数等指标也较BP网络方法提升明显。 展开更多
关键词 储层岩性识别 量子衍生涡流算法 ts 模糊推理模型 模糊集 地震属性
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扩展目标跟踪Student’s t逆Wishart平滑算法
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作者 陈辉 张丁丁 +1 位作者 连峰 韩崇昭 《电子与信息学报》 EI CAS CSCD 北大核心 2024年第8期3353-3362,共10页
脉冲干扰和离群量测信息等因素通常会导致异常的厚尾噪声,这使得以高斯假设为前提的扩展目标跟踪(ETT)估计器的性能急剧降低,针对该问题该文提出一种基于扩展目标随机矩阵模型(RMM)的Student’s t逆Wishart平滑(StIWS)算法。首先,将目... 脉冲干扰和离群量测信息等因素通常会导致异常的厚尾噪声,这使得以高斯假设为前提的扩展目标跟踪(ETT)估计器的性能急剧降低,针对该问题该文提出一种基于扩展目标随机矩阵模型(RMM)的Student’s t逆Wishart平滑(StIWS)算法。首先,将目标的运动状态以及过程噪声和量测噪声建模为Student’s t分布以表征异常噪声对扩展目标概率分布的影响,将目标扩展状态建模为服从逆Wishart分布的随机矩阵。然后,在Student’s t贝叶斯平滑框架下,详细推导了能在扩展目标的多重特征动态演变的过程中有效估计目标状态的StIWS算法。最后,通过扩展目标跟踪的仿真实验结果和真实场景实验结果验证了所提算法的有效性。 展开更多
关键词 扩展目标跟踪 students t平滑 逆Wishart分布 厚尾噪声
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车辆主动悬架自适应变论域T-S模糊控制研究
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作者 李韶华 季广港 +1 位作者 冯桂珍 王贺 《振动.测试与诊断》 EI CSCD 北大核心 2024年第4期733-739,828,共8页
针对传统变论域模糊控制存在过度依赖专家经验、伸缩因子参数不能自适应调整的问题,提出一种车辆主动悬架自适应变论域T-S模糊控制策略,从而提高车辆的行驶平顺性。结合神经网络和T-S模糊推理建立基于自适应神经模糊推理的一阶T-S模糊... 针对传统变论域模糊控制存在过度依赖专家经验、伸缩因子参数不能自适应调整的问题,提出一种车辆主动悬架自适应变论域T-S模糊控制策略,从而提高车辆的行驶平顺性。结合神经网络和T-S模糊推理建立基于自适应神经模糊推理的一阶T-S模糊控制器,利用神经网络的自学习特性产生完善的模糊规则,进而在传统函数型伸缩因子的基础上,将系统误差和误差变化率作为动态参数引入伸缩因子中,实现伸缩因子参数的自适应调整,解决了传统函数型伸缩因子因参数确定难度大导致控制效果差的问题。通过随机工况下的仿真分析和基于相似理论的缩尺实验,对所提出算法的有效性和工况自适应性进行了验证。结果表明,所提出的自适应变论域T-S模糊控制策略具有较强的工况适应性,在不同车速、路面激励下均可有效提高车辆的平顺性并保证轮胎接地安全性。 展开更多
关键词 主动悬架 变论域 伸缩因子 t-s模糊控制 神经模糊系统
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帕金森病患者免疫球蛋白、Th9亚群水平变化及其与IGF-1、S-100B蛋白的相关性
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作者 曹利红 张哲 傅天 《中国免疫学杂志》 CAS CSCD 北大核心 2024年第6期1248-1252,共5页
目的:研究帕金森病(PD)患者免疫球蛋白(IgG、IgA和IgM)、辅助性T细胞亚群Th9水平变化及其与胰岛素生长因子-1(IGF-1)、S-100B蛋白的相关性。方法:选取2020年12月至2022年12月期间在河北省中医院确诊的108例PD患者,将其作为研究组,并根... 目的:研究帕金森病(PD)患者免疫球蛋白(IgG、IgA和IgM)、辅助性T细胞亚群Th9水平变化及其与胰岛素生长因子-1(IGF-1)、S-100B蛋白的相关性。方法:选取2020年12月至2022年12月期间在河北省中医院确诊的108例PD患者,将其作为研究组,并根据患者病变程度分为轻度组(35例)、中度组(44例)和重度组(29例);另选108例健康成人作为对照组。对比研究组和对照组免疫球蛋白和Th9亚群水平,以及轻度组、中度组及重度组免疫球蛋白、Th9亚群、IGF-1和S-100B蛋白水平,采用Pearson相关性分析免疫球蛋白、Th9亚群和IGF-1、S-100B蛋白的相关性。采用Spearman相关性分析PD患者疾病程度和所有差异指标间的相关性。结果:研究组IgM水平较对照组低,且重度组低于中度组,中度组低于轻度组(P<0.05);研究组IgG、IgA、IL-9和Th9亚群水平较对照组高,且重度组高于中度组,中度组高于轻度组(P<0.05)。重度组IGF-1水平低于中度组,中度组低于轻度组;重度组S-100B蛋白水平高于中度组,中度组高于轻度组(P<0.05)。Pearson相关性分析结果显示,PD患者IgM水平与IGF-1水平呈正相关,与S-100B蛋白水平呈负相关;IgG、IgA、IL-9和Th9亚群水平均与IGF-1水平呈负相关,与S-100B蛋白水平呈正相关(P<0.05)。Spearman相关性分析结果显示,PD患者疾病程度与IgM、IGF-1水平呈负相关,与S-100B蛋白、IgG、IgA、IL-9和Th9亚群水平呈正相关(P<0.05)。结论:PD患者IgM水平降低,IgG、IgA、Th9亚群水平升高,且其水平变化与IGF-1、S-100B明显相关,可以用于评估病情的严重程度。 展开更多
关键词 帕金森病 免疫球蛋白 辅助性t细胞亚群 胰岛素生长因子-1 s-100B蛋白
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基于T-S模糊故障树的驱动电机冷却系统可靠性分析
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作者 柳炽伟 郭美华 《客车技术与研究》 2024年第2期19-25,共7页
车用驱动电机液压冷却系统存在故障机理不确定等问题。本文应用模糊数描述其故障概率和故障程度,建立驱动电机冷却系统的T-S模糊故障树模型,计算系统模糊可能性,分析各部件的概率重要度和关键重要度,找出影响系统可靠性的关键部件。
关键词 电动汽车 驱动电机 冷却系统 t-s模糊故障树 可靠性分析
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S-T-S混合式循环互助教学模式用于少学时“化工原理”课程
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作者 吕玲 《教育教学论坛》 2024年第31期157-160,共4页
“化工原理”课程是化工及相关专业的专业基础课程,相关专业的学时少,课程难,需重点解决的问题是“三多”“三不愿”“三不明”。针对痛点问题,提出了线上线下混合式循环互助的创新设计思路,包括:教师帮助学生自制课前、课中、课后习题... “化工原理”课程是化工及相关专业的专业基础课程,相关专业的学时少,课程难,需重点解决的问题是“三多”“三不愿”“三不明”。针对痛点问题,提出了线上线下混合式循环互助的创新设计思路,包括:教师帮助学生自制课前、课中、课后习题,学生帮助教师反馈真实学习情况,学生帮助学生组团互助学习。问卷调查和评教结果显示,在一定程度上解决了“三多”“三不愿”的问题;通过建立“助教团队”反馈不同层次学生的学习情况,较好地解决了“三不明”的问题。学生的成绩与教改前相比有明显提高。 展开更多
关键词 线上线下 s-t-s教学模式 化工原理 痛点问题
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混合差分和多种群粒子群算法的T-S模糊模型辨识
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作者 林国汉 陈壮 《湖南工程学院学报(自然科学版)》 2024年第2期1-6,30,共7页
为提高T-S模型的辨识精度,针对基本粒子群优化(particle swarm optimization,PSO)算法T-S模型全局优化辨识问题,提出混合差分和多种群粒子群算法的T-S模糊模型辨识方法,将T-S模型前件参数和后件参数整体编码进行全局优化辨识.为避免基... 为提高T-S模型的辨识精度,针对基本粒子群优化(particle swarm optimization,PSO)算法T-S模型全局优化辨识问题,提出混合差分和多种群粒子群算法的T-S模糊模型辨识方法,将T-S模型前件参数和后件参数整体编码进行全局优化辨识.为避免基本粒子群的早熟收敛和后期收敛速度慢的缺陷对T-S模型辨识精度和速度的影响,算法将种群分为若干个子群,每个子群根据粒子适应度值自适应调整惯性权重,平衡了算法的开发和探索能力,对子群最优粒子,进行差分操作以增强算法的全局搜索能力,采用全局最优粒子替代随机子群的最优粒子以加强子群间的信息交流,维持粒子多样性.典型非线性系统和混沌系统的仿真结果表明,采用混合差分和多种群粒子群算法辨识的T-S模型具有更高的辨识精度. 展开更多
关键词 t-s模糊系统 粒子群优化 差分进化 多种群
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整体性视域下雷蒙·威廉斯的T.S.艾略特戏剧评论
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作者 张乾坤 《湖南科技学院学报》 2024年第4期53-58,共6页
威廉斯的T.S.艾略特戏剧批评是西方马克思主义戏剧批评史上的经典案例之一。他从整体形式与整体行动的角度切入,前者考察T.S.艾略特文本中的诸要素是否进行了整体把握,是否为经验交流提供了惯例;后者讨论究竟如何理解T.S.艾略特的戏剧,... 威廉斯的T.S.艾略特戏剧批评是西方马克思主义戏剧批评史上的经典案例之一。他从整体形式与整体行动的角度切入,前者考察T.S.艾略特文本中的诸要素是否进行了整体把握,是否为经验交流提供了惯例;后者讨论究竟如何理解T.S.艾略特的戏剧,认为它的核心不是个体的死亡,而是集体对现状的默认与妥协。两种批评的角度虽然存在明显的差异,但共同之处是反复强调整体性。威廉斯的整体性批评视域的形成除了根植于深厚的马克思主义批评传统之外,还受到了T.S.艾略特的伊丽莎白时期戏剧批评、F.R.利维斯的小说与诗歌批评的直接影响。整体性批评视域及其文本实践隐含着激进的政治立场。 展开更多
关键词 t.s.艾略特 戏剧批评 整体形式 整体行动 整体性批评视域
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基于T-S模糊逻辑的混合储能孤岛直流微电网功率分配控制 被引量:1
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作者 张伟杰 顾吉鹏 +3 位作者 张有兵 杨晓东 娄伟 汪斌杰 《电力自动化设备》 EI CSCD 北大核心 2024年第6期135-144,共10页
在含混合储能的直流微电网中,传统阻容下垂控制无法解决由线路电阻和负荷功率波动导致的系统功率分配失衡问题。为此,提出一种基于Takagi-Sugeno(T-S)模糊逻辑的自适应阻容下垂控制方法以实现混合储能的分频分配。根据蓄电池和超级电容... 在含混合储能的直流微电网中,传统阻容下垂控制无法解决由线路电阻和负荷功率波动导致的系统功率分配失衡问题。为此,提出一种基于Takagi-Sugeno(T-S)模糊逻辑的自适应阻容下垂控制方法以实现混合储能的分频分配。根据蓄电池和超级电容的物理特性,建立单个蓄电池支路输出电压、蓄电池组间输出功率差额和阻性下垂系数之间的T-S模糊逻辑关系,以及单个超级电容支路输出功率及其变化率、超级电容组间功率差额和容性下垂系数之间的T-S模糊逻辑关系,并由此构建基于T-S模糊逻辑的阻容下垂控制器。推导含混合储能的直流微电网中各部分的平均阻抗模型,并采用阻抗比分析法对微电网的小信号稳定性进行研究。MATLAB/Simulink仿真结果表明,基于T-S模糊逻辑的阻容下垂控制可保证在线路电阻和负荷功率波动情况下系统功率的合理分配。 展开更多
关键词 直流微电网 混合储能 t-s模糊逻辑 功率分配 稳定性分析
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中国预算绩效管理研究热点及前沿对科技领域的启示--基于CiteSpace的文献计量分析
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作者 赵晨光 陈益艺 +2 位作者 史梅洁 杨云 欧阳进良 《中国科技论坛》 CSSCI 北大核心 2024年第12期117-126,共10页
随着中国政府科技投入的不断加大和全面预算绩效管理改革的落实,科技领域预算绩效管理逐渐引起广泛关注。文章以2001-2022年中文核心数据库中经过数据清洗的3065篇预算绩效管理相关文献和267篇科技领域预算绩效管理相关文献为研究对象,... 随着中国政府科技投入的不断加大和全面预算绩效管理改革的落实,科技领域预算绩效管理逐渐引起广泛关注。文章以2001-2022年中文核心数据库中经过数据清洗的3065篇预算绩效管理相关文献和267篇科技领域预算绩效管理相关文献为研究对象,采用文献计量的分析方法,运用CiteSpace可视化工具,通过研究预算绩效管理的研究热点和前沿,结合已有研究和实践经验,分析其对科技领域预算绩效管理的启示,探讨预算绩效管理在科技领域可能的发展方向,以期为中国科技领域预算绩效管理的研究提供参考。 展开更多
关键词 预算绩效管理 科技 文献计量 CItEsPACE
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Correlative factors of poor prognosis and abnormal cellular immune function in patients with Alzheimer’s disease 被引量:2
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作者 Hua Bai Hong-Mei Zeng +2 位作者 Qi-Fang Zhang Yue-Zhi Hu Fei-Fei Deng 《World Journal of Clinical Cases》 SCIE 2024年第6期1063-1075,共13页
BACKGROUND Alzheimer’s disease(AD)is a serious disease causing human dementia and social problems.The quality of life and prognosis of AD patients have attracted much attention.The role of chronic immune inflammation... BACKGROUND Alzheimer’s disease(AD)is a serious disease causing human dementia and social problems.The quality of life and prognosis of AD patients have attracted much attention.The role of chronic immune inflammation in the pathogenesis of AD is becoming more and more important.AIM To study the relationship among cognitive dysfunction,abnormal cellular immune function,neuroimaging results and poor prognostic factors in patients.METHODS A retrospective analysis of 62 hospitalized patients clinical diagnosed with AD who were admitted to our hospital from November 2015 to November 2020.Collect cognitive dysfunction performance characteristics,laboratory test data and neuroimaging data from medical records within 24 h of admission,including Mini Mental State Examination Scale score,drawing clock test,blood T lymphocyte subsets,and neutrophils and lymphocyte ratio(NLR),disturbance of consciousness,extrapyramidal symptoms,electroencephalogram(EEG)and head nucleus magnetic spectroscopy(MRS)and other data.Multivariate logistic regression analysis was used to determine independent prog-nostic factors.the modified Rankin scale(mRS)was used to determine whether the prognosis was good.The correlation between drug treatment and prognostic mRS score was tested by the rank sum test.RESULTS Univariate analysis showed that abnormal cellular immune function,extrapyramidal symptoms,obvious disturbance of consciousness,abnormal EEG,increased NLR,abnormal MRS,and complicated pneumonia were related to the poor prognosis of AD patients.Multivariate logistic regression analysis showed that the decrease in the proportion of T lym-phocytes in the blood after abnormal cellular immune function(odd ratio:2.078,95%confidence interval:1.156-3.986,P<0.05)was an independent risk factor for predicting the poor prognosis of AD.The number of days of donepezil treatment to improve cognitive function was negatively correlated with mRS score(r=0.578,P<0.05).CONCLUSION The decrease in the proportion of T lymphocytes may have predictive value for the poor prognosis of AD.It is recommended that the proportion of T lymphocytes<55%is used as the cut-off threshold for predicting the poor prog-nosis of AD.The early and continuous drug treatment is associated with a good prognosis. 展开更多
关键词 Alzheimer’s disease Cellular immunity PROGNOsIs t lymphocytes Magnetic resonance spectroscopy
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靶向蛋白S-棕榈酰化修饰在T细胞免疫疗法中的研究进展
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作者 孙丽婷 张为国 童玥 《中国药科大学学报》 CAS CSCD 北大核心 2024年第1期45-52,共8页
S-棕榈酰化是细胞内一种可逆且动态的蛋白质翻译后修饰,参与调控下游靶基因转录、表达以及信号转导,进而影响细胞生命活动。研究发现数千种人类蛋白质经历S-棕榈酰化修饰,表明S-棕榈酰化与疾病发生发展以及治疗之间存在很大程度的关联性... S-棕榈酰化是细胞内一种可逆且动态的蛋白质翻译后修饰,参与调控下游靶基因转录、表达以及信号转导,进而影响细胞生命活动。研究发现数千种人类蛋白质经历S-棕榈酰化修饰,表明S-棕榈酰化与疾病发生发展以及治疗之间存在很大程度的关联性。T细胞是机体抗肿瘤免疫的主力军,多种T细胞免疫相关蛋白受S-棕榈酰化调节。本文围绕S-棕榈酰化对T细胞信号转导的影响及在T细胞免疫疗法中的应用展开论述,为T细胞免疫治疗新靶点及多肽抑制剂的开发提供新思路。 展开更多
关键词 s-棕榈酰化 DHHC t细胞 免疫疗法 肽抑制剂
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基于T-S模糊故障树和剩余寿命的离心泵健康评估方法
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作者 王语嘉 李金波 +1 位作者 侯继洁 马波 《机电工程》 CAS 北大核心 2024年第12期2272-2281,共10页
针对现有离心泵健康评估方法只考虑单部件,无法客观反映离心泵真实健康状态的问题,提出了一种考虑多部件的基于T-S模糊故障树和剩余寿命的离心泵健康评估方法。首先,对离心泵故障进行了T-S模糊故障树建模,在故障树中用T-S门连接了部件... 针对现有离心泵健康评估方法只考虑单部件,无法客观反映离心泵真实健康状态的问题,提出了一种考虑多部件的基于T-S模糊故障树和剩余寿命的离心泵健康评估方法。首先,对离心泵故障进行了T-S模糊故障树建模,在故障树中用T-S门连接了部件与离心泵,用T-S门规则表征了部件失效概率与离心泵失效概率的影响关系;然后,根据部件的劣化可监测性,采用了基于Wiener过程或Weibull分布的寿命预测方法,根据部件的状态监测数据或历史失效记录,计算了部件的失效概率;最后,根据部件失效概率和T-S门算法,计算了离心泵失效概率和健康因子,得到了离心泵健康状态及其使用和维修建议,并将该健康评估方法应用于离心泵试验台数据集、西安交通大学和SY公司合作开发的(XJTU-SY)数据集。研究结果表明:离心泵试验台中离心泵健康因子为0.789,健康状态为比较健康,该方法综合考虑多部件对离心泵进行状态评估;采用XJTU-SY数据集进行验证可知,相较于基于单部件的健康评估方法,该方法评估健康因子始终低于0.6,且降至0.4的时间明显提前于基于单部件的健康评估方法,评估结果更准确。该方法可为离心泵健康评估方法的改进提供参考。 展开更多
关键词 离心泵 t-s模糊故障树 健康状态评估 健康因子 失效概率计算 t-s门算法
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