Research on the Effect of Comprehensive Intervention in the Clinical Treatment of Patients with Type 2 Diabetes Mellitus

Objective:This study aims to explore the value of comprehensive intervention in the clinical treatment of patients with type 2 diabetes mellitus complicated with hypertension.Methods:90 patients with type 2 diabetes and hypertension were selected and divided into a control group and an intervention group according to the random number table method,with 45 cases in each group.The control group received conventional treatment,and the intervention group received comprehensive intervention on the basis of the control group,including a diet plan,an exercise program,scientific treatment,regular monitoring,and psychological counseling.The blood sugar,blood pressure,and other indicators of the two groups were compared.Results:After 5 months of intervention,the fasting blood glucose,postprandial 2 h blood glucose,glycosylated blood glucose protein,diastolic blood pressure,systolic blood pressure,mean arterial pressure,and other indicators of the intervention group were significantly lower than the control group(P<0.05),and the rate of decrease was significantly greater than that of the control group(P<0.05).Conclusion:Comprehensive intervention for patients with type 2 diabetes mellitus and hypertension helps in controlling blood sugar and lowering blood pressure,with clinical significance.

Elementary school comprehensive intervention and myopia development:the Wenzhou Epidemiology of Refraction Error Study

AIM:To investigate the effects of school-basedcomprehensive intervention on myopia development inelementary school children.METHODS:As a part of the Wenzhou Epidemiologyof Refraction Error Study,there were 1524 participatingelementary students(730 girls,47.9%)in grades 1 to3 from three campuses of one school,aged 7.3±0.9y,who were examined twice every year for a 2.5y follow upperiod.Comprehensive intervention and other reminderswere given at school every semester for the interventiongroup.The control group did not receive comprehensiveintervention and did not have reminders of it.RESULTS:There were 651 students in the interventiongroup[mean age 7.3±0.9y;294(45.2%)girls]and 737students in the control group[mean age 7.2±0.9y;346(46.9%)girls].Overall mean myopia progression duringthe 2.5y follow-up was-0.49±1.04 diopters(D)in theintervention group and-0.65±1.08 D in the control group(P=0.004).The majority that not get myopia at baselinespherical equivalent(SE≤-1.0 D).Their mean myopiaprogression during the 2.5y follow-up was-0.37±0.89 Din the intervention group and-0.51±0.93 D in the controlgroup(27.5%reduction,P=0.009);Overall,mean axiallength elongation was less in the intervention group(0.56±0.32 mm)than in the control group(0.61±0.38 mm,10.5%reduction,P=0.009).The percentage of close reading distance(<30 cm)in the intervention group was less than in the control group(73.4%vs 76.2%,P<0.001),the percentage of everyday perform eye exercises in the intervention group was more than in the control group(27.8%vs 20.7%,P<0.001)30mo later.CONCLUSION:The comprehensive intervention program at elementary school has a significant alleviating effect on myopia progression for children during the 2.5y follow-up,especially for those non-myopia at baseline.

Study on Chronic Diseases Comprehensive Intervention in Baoji of Shaanxi Province in China

Background: There is very limited data available about the epidemiology trial on chronic diseases comprehensive intervention. The aim of this study was to assess the effect of comprehensive intervention on chronic diseases in Baoji and provide basis for the improvement of chronic diseases intervention measures. Methods: Using four stages stratified random sampling method, comprehensive intervention measures were implemented on intervention group (575 individuals) respectively aimed at three crowds of whole population, high risk population and chronic diseases patients. The control group (782 individuals) did not receive special treatment. Two groups were evaluated effect after one year observation. Results: The chronic diseases prevalence rate of whole population in intervention group was lower than that in control group (P < 0.05), the blood pressure level and smoking proportion of high risk population in intervention group were lower than in control group (P < 0.05), and the blood pressure, blood glucose control rate of chronic diseases patients in intervention group were higher than in control group (P < 0.05). Conclusion: Comprehensive intervention could prevent the rise of chronic diseases prevalence. The intervention is effective in reducing or halting risk factors of high risk population, particularly in controlling blood pressure, blood glucose of patients. We should establish government leading, department cooperation, social participation, longtime and classified comprehensive intervention mechanism of chronic diseases. We believe that whole population should control the risk factors, high risk population should early diagnosis and treatment, chronic diseases patients should normalized management, and it could be applied in other counties.

Effect of comprehensive intervention on hypertension control among employees in the Chinese stated-owned enterprise:a cluster controlled trial

Objective To evaluate the effect of a workplace-based comprehensive intervention strategy on the improvement of blood pressure (BP) control.Methods A cluster controlled trail, with workplaces (clusters)assigned to either the intervention or control group. Totally, 30 statedowned enterprises across China were included, among which 20were allocated to the intervention group and 10 to the control group.

Risk factors for secondary infection after liver failure and effect of comprehensive nursing intervention

BACKGROUND In patients with liver failure(LF),the high rate of secondary infections,which are associated with poor prognosis,highlights the clinical significance of understanding the underlying risk factors and implementing targeted intervention programs.AIM To investigate risk factors for secondary infections in patients with LF and evaluate the effectiveness of comprehensive nursing interventions.METHODS This retrospective study included 64 patients with LF,including 32 with and 32 without secondary infections.A questionnaire was used to collect data on age;laboratory parameters,including total and direct bilirubin,prothrombin time,blood ammonia,and other biochemical parameters;invasive procedures;and complications.Patients with secondary infections received comprehensive nursing intervention in addition to routine nursing care,whereas those without secondary infections received only routine nursing care to compare the effect of nursing intervention on outcomes.RESULTS The infection rate,which was not associated with age or complications,was significantly associated with biochemical parameters and invasive procedures(P<0.05).The infection rate was 61.6%in patients who had undergone invasive procedures and 32.1%in those who had not undergone invasive procedures during the hospital stay.The infection rate was also significantly associated with the type of LF(P<0.05),with the lowest rate observed in patients with acute LF and the highest rate observed in those with subacute LF.The nursing satisfaction rate was 58.3%in the uninfected group and 91.7%in the infected group,indicating significantly higher satisfaction in the infected group(P<0.05).CONCLUSION In patients with LF,the rate of secondary infections was high and associated with biochemical parameters and type of LF.Comprehensive nursing intervention can improve patient satisfaction.

Effect of comprehensive management combined with cognitive intervention on patient cooperation and complications during digestive endoscopy

BACKGROUND As lifestyles continue to change worldwide,the incidence of digestive tract carcinoma has gradually increased.Digestive endoscopy is an important tool that can assist in the diagnosis,treatment,and surgical intervention for this disease.However,the examination process is affected by many factors,and patient cooperation is often poor,which can increase the risk of complications.AIM To explore the effects of integrated management and cognitive intervention on cooperation and complications in patients undergoing endoscopy for early gastrointestinal neoplasms.METHODS A total of 354 patients with early stage gastrointestinal cancer who underwent digestive endoscopy procedures between January and December 2023 at our hospital were divided into observation and control groups(177 patients in each group)in a randomized controlled blind trial.The control group received routine interventions,while the observation group received comprehensive integrated management combined with cognitive interventions.We compared the changes in adverse mood,discomfort,examination time,cooperation with the examination,and complications before and after the intervention between the two groups.RESULTS The self-rated anxiety and depression scale scores were lower in the observation group than in the control group(P<0.05).The visual analog scale scores for discomfort during intubation and examination were also lower in the observation group than in the control group(P<0.05).Furthermore,the examination time was shorter in the observation group than in the control group(P<0.05),and the degree of cooperation(94.35%)was higher in the observation group than in the control group(84.75%;P<0.05).Lastly,the incidence rates of gastrointestinal adverse reactions(10.17%vs 20.34%),choking agitation(14.69%vs 24.86%),abdominal pain(8.47%vs 18.08%),and muscle tension(5.08%vs 14.12%)were all lower in the observation group than in the control group(P<0.05).CONCLUSION Integrated management and cognitive intervention in early gastrointestinal neoplasm endoscopy alleviate mood,reduce discomfort,shorten examinations,improve cooperation,and reduce complications.

Analysis of The Effect of Comprehensive Nursing Intervention on Improving Blood Sugar Levels and Treatment Compliance in Elderly Patients with Diabetes

Objective: To analyze the effect of comprehensive nursing intervention on improving blood glucose levels and treatment compliance in elderly patients with diabetes. Methods: One hundred and forty-eight elderly patients with diabetes were selected and randomly divided into a control group and an observation group, with 74 cases each. The control group received routine nursing intervention and the observation group received comprehensive nursing intervention. The blood sugar levels, treatment compliance, and nursing satisfaction of the two groups of patients before and after intervention were compared. Results: After the intervention, the fasting plasma glucose (FPG) (t = 7.729), 2 hours postprandial glucose (PPG) (t = 8.343), and HbA1c (t = 6.929) levels of patients in the observation group were significantly lower than those in the control group (P < 0.001). The observation group (71/95.95%) had a higher compliance rate than the control group (54/72.97%) (χ^(2)=14.877, P < 0.001). The comprehensive nursing satisfaction rate of the observation group (73/98.65%) was higher than that of the control group (56/75.68%) (χ^(2)=17.451, P < 0.001). Conclusion: In caring for elderly patients with diabetes, comprehensive nursing intervention effectively reduced patients’ blood sugar levels and improved treatment compliance and nursing satisfaction.

Prevention of Reservoir Water Bloom by Bio-manipulation

Siminghu Reservoir already transformed into ＂ the algae muddy＂ type,and had nonclassical bio-manipulation practice using Hypophthalmichthys molitix and Aristichthys nobilis to feed the plankton,control water bloom and transform the organic matters into fish product. Through the analysis of the limited data,we think that water bloom of Siminghu Reservoir can be prevented to some extent by breeding H. molitix and A. nobilis,and it can slow down eutrophication of reservoir but cannot control the eutrophication tendency. We must take a variety of comprehensive management measures to control eutrophication from the angle of basin control,and guarantee safety of drinking water resources.

Effect of Comprehensive Nursing Intervention in Patients with Urinary Incontinence After Radical Prostatectomy

Objective:To explore and analyze the clinical effect of comprehensive nursing intervention in patients with urinary incontinence after radical prostatectomy.Methods:84 patients with urinary incontinence after radical prostatectomy admitted to the Urology Department between May 2021 and May 2023 were included in this study.The patients were divided into a comprehensive group and a control group,with 42 cases in each group through a double-blind mechanism.The comprehensive group received comprehensive nursing care,and the control group received primary nursing care.The duration of indwelling urinary catheters and urinary incontinence;psychological performance and living conditions were compared between the two groups.Results:The duration of the indwelling urinary catheter and urinary incontinence of the patients in the comprehensive group were significantly shorter than that in the control group(P<0.05).Before nursing,there was no statistically significant difference in the anxiety,depression,and other psychological manifestations between the two groups(P>0.05);after nursing,the comprehensive group’s anxiety,depression,and other psychological manifestations of the comprehensive group were significantly lower than those of the control group(P<0.05).Before nursing,there was no statistically significant difference in the physical function,mental state,emotional state,and physical recovery of the patients between both groups(P>0.05);after nursing,the physical function,mental state,emotional state,physical recovery of the patients in the comprehensive group were significantly better than those of the control group.Besides,the living conditions of the patients in the comprehensive group were also significantly better than the control group’s(P<0.05).Conclusion:Comprehensive nursing intervention can effectively improve symptoms of urinary incontinence after radical prostatectomy,reduce inner pressure,and improve living standards.

Effects of comprehensive nursing with cognitive behavioral therapy in orthodontic osteodilated arch treatment

BACKGROUND This work explored the effects of cognitive behavior therapy(CBT)-based comprehensive nursing intervention(CNI)mode in arch expansion to treat patients with orthodontic osteodilated arch(OOA).AIM To explore the application effect of CBT-based CNI model in orthodontic expansion arch treatment.METHODS Using convenient sampling method,81 patients with OOA were selected and rolled into a control group(Ctrl group,40 cases)and an observation group(Obs group,41 cases).During the treatment,patients in the Ctrl group received routine nursing intervention mode,and the those in the Obs group received CBT mode on the basis of this.Before and after intervention,the incidence of oral mucositis,the mastery rate of correct arch expansion method,self-rating anxiety scale score,soft scale index,and plaque index were compared for patients in different groups.In addition,satisfaction and complications were comparatively analyzed.RESULTS Incidence of oral mucositis in the Obs group was lower(14.6%vs 38.5%),and the mastery rate of correct arch expansion method was obviously higher(90.2%vs 55.0%)was obviously higher(all P<0.05).Meanwhile,the soft scale index and plaque index in the Obs group were much lower(P<0.05).The compliance(90.24%)and satisfaction(95.12%)in the Obs group were greatly higher(P<0.05).CONCLUSION The CBT-based CNI mode greatly improved the mastery rate of correct arch expansion method during arch expansion in treating patients with OOA and enhanced the therapeutic effect of arch expansion and the oral health of patients,improving the patient compliance.

Early Intervention Facilitates Neuropsychological Development in Children with Autism and Attention Deficit Hyperactivity Disorder

Objective:This study aims to investigate the impact of early intervention on neuropsychological development in children with autism and attention deficit hyperactivity disorder(ADHD),providing effective intervention strategies for clinical practice.Methods:A total of 130 children with autism and ADHD who visited the hospital between June 2023 and June 2024 were selected as study subjects and randomly divided into an intervention group and a control group,with 65 children in each group.The intervention group received a one-year early comprehensive intervention,including behavioral therapy,cognitive training,and family guidance,while the control group only received routine medical care.The neuropsychological development assessment scale was used to evaluate both groups before and after the intervention to compare changes in their neuropsychological development levels.Results:Children in the intervention group showed significant improvements in cognitive function,social skills,language ability,and attention concentration,with an average improvement score of 23.5 points.Children in the control group did not show significant improvements in these areas,with an average improvement score of only 5.8 points.The difference between the two groups was statistically significant(P<0.05).Conclusion:Early comprehensive intervention has a significant promoting effect on the neuropsychological development of children with autism and ADHD.Targeted behavioral therapy,cognitive training,and family guidance can effectively enhance children’s cognitive,social,language,and attention abilities,laying a solid foundation for their future overall development.Therefore,it is recommended to actively promote and apply early intervention strategies in clinical practice.

The effects of comprehensive nursing interventions on sexual functions in young and middle-aged patients with coronary stent implantation

Objective: To study the effects of comprehensive nursing interventions on sexual functions in young and middle-aged patients with coronary stent implantation. Methods: 96 cases of coronary stent implantation were randomly divided into control group and intervention group (experimental group) with each group of 48 cases. The control group received the routine nursing measures after the coronary stent implantation and the experimental group was treated by the comprehensive nursing interventions such as psychological nursing, education of sexual knowledge, playing the full enthusiasm of spouse and appropriate exercise therapy on basis of the routine nursing measures. The two groups were given the questionnaire of brief male sexual function questionnaire (BSFI), Chinese patients with premature ejaculation sexual function score (C-ISFPE) and the international index of erectile function (IIEF-5). The scores of BSFI, C-ISFPE and IIEF-5 were compared between the two groups. Results: There were 29 cases who were satisfied with sexual life on the whole (≤1), 26 cases with different degrees of premature ejaculation symptoms and 21 cases with erectile dysfunctions, which were respectively 27.08%, 30.2% and 21.87% of the total number. The scores of BSFI, C-ISFPE and IIEF-5 inthe experimental group were significantly increased after the interventions (P P IIEF-5 scores in the two groups were significantly different

Guidelines and standards for comprehensive clinical diagnosis and interventional treatment for diabetic foot in China(Issue 7.0)

Diabetic foot(DF)is one of the most common complications of diabetes and is associated with high morbidity,disability,lethality and low cure-rate.The clinical diagnosis and treatment of DF need to be standardized.The Chinese Diabetic Foot Cell and Interventional Therapy Technology Alliance has released six editions of guidelines and standards for clinical diagnosis and interventional treatment of DF,which filled the gap in the domestic DF treatment standard and played an important role in improving the level of diagnosis and treatment in China.In line with the latest developments in diagnosis and treatment,the Alliance,along with other 89 institutions,developed and issued the new edition based on the sixth edition to help standardize the clinical diagnosis and treatment of DF in China.

INTERVENTION CHEMOTHERAPY IN COMPREHENSIVE TREATMENT OF ADVANCED NASOPHARYNGEAL CARCINOMA

Objective: To study the use of interventional chemotherapy in comprehensive treatment for advanced nasopharyngeal carcinoma. Methods: Interventional chemotherapy with multi-drugs including cisplatin (DDP) 100 mg, 5-fluorouracil (5-FU) 1000 mg and bleomycin (BLM) 16 mg was used to treat 30 cases with advanced nasopharyngeal carcinoma before radiotherapy. 50 cases that received radiotherapy alone were used as a control group. The methods, time and dose schedule of radiotherapy were similar in the two groups. Results: The primary lesions in 16 cases and the cervical lymph nodes in 12 cases were reduced hi size after interventional chemotherapy. Radiation doses of those in complete response in their primary lesion and cervical lymph nodes were lower than that of the control group (P<0.05). The complete response rate of study group was 83.3% and that of control group was 72.0% (P<0.05). Conclusion: Interventional chemotherapy plus radiotherapy is a valuable treatment method in advanced nasopharyngeal carcinoma.

Observation on the Effect of Comprehensive Nursing Intervention for Patients with Chronic Obstructive Pulmonary Disease

This study focused on the observation effect of the comprehensive nursing intervention in patients with chronic obstructive pulmonary disease.A total of 64 patients with the chronic obstructive pulmonary disease were selected as subjects.The patients were divided into two groups according to a randomized method.The observation group and the control group were the same in both groups(n=32),study time from June 2017 to August 2018,the selection of patients in the study time,the standard treatment and routine care to give way to the control group.The observation groups comprehend nursing intervention.The two groups of patients compared with nursing effects,nursing satisfaction,lung function levels before and aftercare,care adherence,hospitalization days,and satisfaction scores.The observation group was better than the control group in terms of nursing effect,nursing satisfaction,lung function level before and after nursing,nursing compliance,hospitalization days,and satisfaction score.The comprehensive nursing intervention of patients with the chronic obstructive pulmonary disease has significant effects and is worthy of further promotion and application.

Effect of Comprehensive Nursing Intervention on Intestinal Preparation Quality of Hospitalized Patients undergoing Colonoscopy

Objective:To explore the impact of comprehensive nursing intervention on the quality of intestinal preparation in the process of intestinal preparation for hospitalized patients undergoing colonoscopy.Methods:A total of 320 patients underwent colonoscopy in our department from January to June 2021.They were grouped by random number table.There were 160 cases in the control group and 160 cases in the observation group.The adverse reactions of intestinal preparation and the cleanliness of intestinal preparation were analyzed.Results:Through comprehensive nursing intervention,it can be found that the incidence of adverse reactions in the preparation of colonoscopy in the control group was 24.38%,and that in the observation group was 13.48%.The results showed that the incidence of adverse reactions in the preparation of colonoscopy was significantly lower than that in the control group(P<0.05),which indicates that the difference was statistically significant.In the control group,105 people qualified in intestinal cleanliness score(>5 points)during enteroscopy preparation,and the cleanliness qualification rate was 65.63%.In the observation group,139 people qualified in intestinal cleanliness score(>5 points)during enteroscopy preparation,and the cleanliness qualification rate was 86.88%.The cleanliness qualification rate of enteroscopy preparation was significantly higher than that of the control group,and P<0.05,which indicates that the difference was statistically significant.Conclusion:Comprehensive nursing intervention can promote the quality of preparation of patients for colonoscopy,improve the compliance of patients and improve the accuracy of examination effect.

Improving the Reading Skills of ALS Learners Through Project RICE(Reading Intervention and Comprehension Enhancement)

One of the major problems in the education sector is the reading skills of learners.Students enrolled in the Alternative Learning System(ALS)also experienced this scenario due to several circumstances.This study focused on the improvement of reading comprehension skills of ALS learners by means of project RICE(Reading Intervention and Comprehension Enhancement)as well as the issues and challenges.A quasi-experimental design was utilized in this study which was participated by 54 learners,composed of 27 learners under the experimental group and 27 under the control group.The result revealed that the learners in the experimental group changed from frustration level to instructional level after the implementation of project RICE while the learners in the control group changed from instructional level to inde-pendent level,thereby signifying a significant difference and the effectiveness of the project.Additionally,issues with time and resources were often encountered by the learners.

rTMS联合综合康复干预对孤独症谱系障碍患儿临床症状及语言功能康复的影响

目的探究重复经颅磁刺激(repetitive transcranial magnetic stimulation,rTMS)联合综合康复干预对孤独症谱系障碍(autism spectrum disorder,ASD)患儿临床症状及语言功能康复的影响。方法选取2021年8月~2023年5月在湖南省儿童医院康复中心接受治疗的141例ASD儿童,采用随机数表法分为观察组(72例)和对照组(69例)。对照组患儿给予常规综合康复治疗,观察组患儿在对照组基础上给予rTMS治疗,并对所有患儿进行5个月跟踪随访。对比相关参数及量表评分。结果治疗后,观察组孤独症行为量表(autism behavior checklist,ABC)和儿童孤独症评定量表(childhood autism rating s cale,CARS)评分均显著低于对照组(P<0.05),对比0~6岁小儿神经心理发育检查表得分,观察组治疗后适应能力、社交能力及语言功能得分均显著高于对照组(P<0.05),两组粗大动作、精细动作得分无显著差异(P>0.05)。末次随访时,观察组患儿的言语行为里程碑评估和安置计划(verbal behavior milestones assessment and placement program,VB-MAPP)得分显著高于对照组(P<0.05)。结论rTMS联合综合康复干预可显著改善ASD症状,提高患儿神经、语言、社交及感知等能力。

应用综合干预措施对促进住院患者抗菌药物治疗前病原学送检的效果评价

目的探讨应用综合干预措施对促进住院患者抗菌药物治疗前病原学送检的效果。方法选取2020年1月—2021年12月某三甲医院治疗性使用抗菌药物的住院患者为研究对象,2021年1月开始实施综合干预措施,比较干预前组(2020年1—12月)和干预后组(2021年1—12月)抗菌药物治疗前病原学送检率、送检分类和重点监管科室送检率。结果共纳入治疗性使用抗菌药物的住院患者10239例,其中干预前组4526例,干预后组5713例。干预后的抗菌药物治疗前、限制级抗菌药物治疗前、特殊级抗菌药物治疗前病原学送检率分别为94.56%、94.72%、96.03%,高于干预前的83.74%、84.47%、84.95%,差异均有统计学意义(均P<0.05)。干预后的指向性病原体送检率为64.87%,高于干预前的28.04%,差异均有统计学意义(均P<0.05)。干预后的重症医学科、呼吸与危重症医学科、儿科、神经外科和普通外科治疗性使用抗菌药物病原学送检率分别为93.20%、91.17%、92.20%、94.12%、91.15%,高于干预前的85.00%、82.19%、83.20%、83.33%、83.03%,差异均有统计学意义(均P<0.05)。结论应用综合干预措施可提高住院患者抗菌药物治疗前病原学送检率,应密切关注医院感染诊断相关病原学送检指标和无菌体液送检指标。

微创手术机器人主操作手设计与优化

主操作手作为机器人辅助微创外科手术中人机交互的唯一接口,提高其灵活性和紧凑性,对手术效果具有重要意义。设计了一款8自由度(Degree Of Freedom,DOF)串联型主操作手,其能够实现位置、姿态和开合力矩输出。采用改进的D-H参数法和解析法,分别建立了主操作手正运动学和逆运动学模型,并通过蒙特卡洛法分析了主操作手工作空间,验证了其设计要求;求解了主操作手雅可比矩阵,基于全局灵巧度指标和工作空间利用率指标,定义了主操作手的综合性能指标;利用遗传算法对主操作手的关键连杆尺度参数进行了优化。结果表明,优化后主操作手的综合性能指标相对于优化前提高了18.41%;主操作手在满足工作空间设计要求的基础上,机构更加紧凑且具备了良好的运动性能。