To study the effects of different durations of forward masker sound on neuronal firing and rate-intensity function(RIF)of mouse inferior collicular(IC)neurons,a tone relative to 5 dB above the minimum threshold(re MT+...To study the effects of different durations of forward masker sound on neuronal firing and rate-intensity function(RIF)of mouse inferior collicular(IC)neurons,a tone relative to 5 dB above the minimum threshold(re MT+5 dB)of the best frequency of recorded neurons was used as forward masker sound under free field stimulation condition.The masker durations used were 40,60,80,and 100 ms.Results showed that as masker duration was increased,inhibition in neuronal firing was enhanced(P<0.0001,n=41)and the latency of neurons was lengthened(P<0.01,n=41).In addition,among 41 inhibited IC neurons,90.2%(37/41)exhibited narrowed dynamic range(DR)when masker sound duration was increased(P<0.0001),whereas the DR of 9.8%(4/41)became wider.These data suggest that masking effects of different durations of forward masker sound might be correlated with the amplitude and duration of inhibitory input to IC neurons elicited by the masker sound.展开更多
The present study explores the forward mask-ing of the two-tone stimuli in sequence that evoked responses in the inferior colliculus (IC) of the echolocating bats. The results indicate that forward masking is obvious ...The present study explores the forward mask-ing of the two-tone stimuli in sequence that evoked responses in the inferior colliculus (IC) of the echolocating bats. The results indicate that forward masking is obvious in the acoustic responses of the IC neurons to the two-tone stimuli. Meanwhile the intensity sensitivity of the neurons respond-ing to the probe increases with the inter-tone interval de-creasing. The effects of forward masking are correlated with the relative intensity and the interval between the masker and probe. That is, the effects of forward masking are re-duced with the masker intensity decreasing and enhanced with the probe intensity decreasing and the inter-tone inter-val shortened. The present study suggests that there is a cor-relation between the characteristics of the response to the probe and the dynamic conditions of the postsynaptic cur-rents in the IC neurons.展开更多
基金supported by the National Natural Science Foundation of China (No.30470564).
文摘To study the effects of different durations of forward masker sound on neuronal firing and rate-intensity function(RIF)of mouse inferior collicular(IC)neurons,a tone relative to 5 dB above the minimum threshold(re MT+5 dB)of the best frequency of recorded neurons was used as forward masker sound under free field stimulation condition.The masker durations used were 40,60,80,and 100 ms.Results showed that as masker duration was increased,inhibition in neuronal firing was enhanced(P<0.0001,n=41)and the latency of neurons was lengthened(P<0.01,n=41).In addition,among 41 inhibited IC neurons,90.2%(37/41)exhibited narrowed dynamic range(DR)when masker sound duration was increased(P<0.0001),whereas the DR of 9.8%(4/41)became wider.These data suggest that masking effects of different durations of forward masker sound might be correlated with the amplitude and duration of inhibitory input to IC neurons elicited by the masker sound.
基金supported by the National Natural Science Foundation of China(Grant No.30170313)the Ph.D.Education Fund of China(Grant No.2000026905)and the NSF of USA.`
文摘The present study explores the forward mask-ing of the two-tone stimuli in sequence that evoked responses in the inferior colliculus (IC) of the echolocating bats. The results indicate that forward masking is obvious in the acoustic responses of the IC neurons to the two-tone stimuli. Meanwhile the intensity sensitivity of the neurons respond-ing to the probe increases with the inter-tone interval de-creasing. The effects of forward masking are correlated with the relative intensity and the interval between the masker and probe. That is, the effects of forward masking are re-duced with the masker intensity decreasing and enhanced with the probe intensity decreasing and the inter-tone inter-val shortened. The present study suggests that there is a cor-relation between the characteristics of the response to the probe and the dynamic conditions of the postsynaptic cur-rents in the IC neurons.
