This paper aimed to explore the correlation between Morus alba L. leaf node and its size or mass change and provide a theoretical basis for the development of scientific Morus alba L. cultivation technology. During 20...This paper aimed to explore the correlation between Morus alba L. leaf node and its size or mass change and provide a theoretical basis for the development of scientific Morus alba L. cultivation technology. During 2016-2017,the correlation between Morus alba L. leaf node and its size or mass change was investigated and researched. Results showed that through the correlation coefficient analysis,there was a weakly positive correlation between the leaf node and some indicators such as( leaf length ÷ leaf width) and petiole length,there was a weakly negative correlation between the leaf node and some indicators such as leaf width,( leaf length + leaf width),( leaf length × leaf width) and leaf mass,and there was a weakly negative correlation between the leaf node and the other indicators; there was a highly positive correlation between the leaf mass and some indicators such as Morus alba L. leaf length,leaf width,( leaf length + leaf width) and( leaf length × leaf width),there was a significantly positive correlation between the leaf mass and some indicators such as petiole transverse diameter in width and petiole mass,and there was a weakly positive correlation between the leaf mass and some indicators such as petiole transverse diameter in thickness. In terms of significant level of difference,it was found that there was no significant difference in the correlation coefficients between the leaf nodes on the Morus alba L. shoots and some indicators such as leaf length,leaf width,( leaf length + leaf width),( leaf length × leaf width) and leaf mass; there was an extremely significant difference in the correlation coefficients between the leaf mass and some indicators such as Morus alba L. leaf length,leaf width,( leaf length + leaf width),( leaf length × leaf width),petiole transverse diameter in width and petiole mass; there was no significant difference in the correlation coefficients between the leaf mass and the other indicators. The regression analysis was performed on the leaf node and leaf length,leaf width,( leaf length + leaf width),( leaf length × leaf width),( leaf length ÷ leaf width),petiole length,petiole diameter in width,petiole diameter in thickness,petiole mass and leaf mass. Significance F values were0. 4864,0. 1995,0. 2888,0. 3004,0. 2350,0. 2407,0. 8925,0. 5227,0. 7022 and 0. 2000,respectively,that is,there was an extremely significant difference between Morus alba L. leaf node and petiole diameter in width,there was a significant difference between Morus alba L.leaf node and petiole mass,and there was no significant difference between Morus alba L. leaf node and the other indicators. The comparative analysis of quadratic curve regression equation and linear regression equation was performed on some indicators such as leaf length,and it was found that the R value between the leaf node and petiole diameter in width was in line with the logarithmic curve regression equation,and the other R values of quadratic curve regression equation was larger than the other R values of linear regression equation,indicating that different Morus alba L. leaf nodes,leaf length,leaf mass and other indicators were in line with the quadratic curve regression equation. It was concluded that by investigating the leaf node on the Morus alba L. shoots and regression equation,we could predict the leaf size,leaf mass and other indicators,and we could take the leaf node on the Morus alba L. shoots as a main factor affecting the Morus alba L. leaf size and mass.展开更多
Lung cancer is the most common cancer worldwide. In the United States, it causes more cancer-related deaths than the next four causes （breast cancer, prostate cancer, colon cancer, and pancreatic cancer） of cancer-r...Lung cancer is the most common cancer worldwide. In the United States, it causes more cancer-related deaths than the next four causes （breast cancer, prostate cancer, colon cancer, and pancreatic cancer） of cancer-related mortality combined （1）. About 30% of people have already progressed to stage III lung cancer and 40% to stage IV at the time they are diagnosed （2）. Although chest X-ray and sputum cytology, when applied in health check-ups, can identify some relatively small tumors, they are not able to lower the overall mortality （3）. More recently,展开更多
目的 ：肥胖和乳腺癌密切相关,但其与腋窝淋巴结状态的关系尚不清楚。本文探讨了肥胖与乳腺癌患者腋窝淋巴结状态的相关性。方法：入组306例乳腺癌患者,根据体质指数（body mass index,BMI）分组,回顾性分析患者BMI与肿瘤病理特征,尤其...目的 ：肥胖和乳腺癌密切相关,但其与腋窝淋巴结状态的关系尚不清楚。本文探讨了肥胖与乳腺癌患者腋窝淋巴结状态的相关性。方法：入组306例乳腺癌患者,根据体质指数（body mass index,BMI）分组,回顾性分析患者BMI与肿瘤病理特征,尤其与腋窝淋巴结状态之间的关系。结果：患者平均年龄48岁（范围21~81岁）,平均BMI 25.1,在确诊乳腺癌时54.4%（n=166）的患者BMI正常,45.6%（n=140）的患者BMI≥25。入组患者中,59.6%无腋窝淋巴结转移,40.4%有腋窝淋巴结转移。肥胖组（BMI≥25）腋窝淋巴结切除数量大于正常体重组（BMI〈25.0）,分别为（20.4±11.4）个和（18.1±10.5）个,差异有统计学意义（P〈0.01）。腋窝淋巴结转移的数量在正常体重组、肥胖组分别为（3.15±6.1）、（3.7±6.4）个（P〉0.05）。正常体重组中有、无淋巴结转移的患者比例分别是39.2%和60.8%;肥胖组中分别为41.4%和58.6%（P〉0.05）,有、无淋巴结转移与BMI没有相关性。结论：肥胖乳腺癌患者中切除的腋窝淋巴结数量较正常体重者多,但是发生淋巴结转移的患者比例、淋巴结转移数量与BMI之间均没有相关性。展开更多
目的:分析有腋窝淋巴结转移和无腋窝淋巴结转移的乳腺浸润性导管癌患者血清中的差异蛋白,筛选与乳腺癌转移相关的生物标志物和治疗靶点。方法:本研究采用定量蛋白质组学串联质谱标签(tandem mass tag,TMT)标记技术分别对14例有腋窝淋巴...目的:分析有腋窝淋巴结转移和无腋窝淋巴结转移的乳腺浸润性导管癌患者血清中的差异蛋白,筛选与乳腺癌转移相关的生物标志物和治疗靶点。方法:本研究采用定量蛋白质组学串联质谱标签(tandem mass tag,TMT)标记技术分别对14例有腋窝淋巴结转移及14例无腋窝淋巴结转移的乳腺癌患者血清蛋白进行检测,并对蛋白质进行定量分析,筛选出发生显著变化的差异蛋白,再搜索Uniprot数据库和用Proteome Discoverer软件分析,进一步进行生物信息学分析。结果:有腋窝淋巴结转移组中共筛选出差异蛋白119个,其中6个表达上调,113个表达下调。基因本体(gene ontology,GO)注释分析和功能聚类分析表明,这些差异蛋白质主要定位于细胞外区,与肿瘤的生物合成、细胞增殖、血管生成相关。Western boltting和qRT-PCR验证了K1C19(下调0.11倍)和PSME2(上调2.02倍)的表达。结论:TMT定量蛋白组学方法能有效筛选有腋窝淋巴结转移的和无腋窝淋巴结转移的乳腺癌患者血清中的差异蛋白。其中,K1C19和PSME2是值得进一步研究的乳腺癌淋巴结转移的候选血清标志物。展开更多
基金Supported by Achievement Cultivation and Talent Training Project of Guizhou Academy of Agricultural Sciences[Qian Nong Ke Yuan CR He Zi(2014)52]
文摘This paper aimed to explore the correlation between Morus alba L. leaf node and its size or mass change and provide a theoretical basis for the development of scientific Morus alba L. cultivation technology. During 2016-2017,the correlation between Morus alba L. leaf node and its size or mass change was investigated and researched. Results showed that through the correlation coefficient analysis,there was a weakly positive correlation between the leaf node and some indicators such as( leaf length ÷ leaf width) and petiole length,there was a weakly negative correlation between the leaf node and some indicators such as leaf width,( leaf length + leaf width),( leaf length × leaf width) and leaf mass,and there was a weakly negative correlation between the leaf node and the other indicators; there was a highly positive correlation between the leaf mass and some indicators such as Morus alba L. leaf length,leaf width,( leaf length + leaf width) and( leaf length × leaf width),there was a significantly positive correlation between the leaf mass and some indicators such as petiole transverse diameter in width and petiole mass,and there was a weakly positive correlation between the leaf mass and some indicators such as petiole transverse diameter in thickness. In terms of significant level of difference,it was found that there was no significant difference in the correlation coefficients between the leaf nodes on the Morus alba L. shoots and some indicators such as leaf length,leaf width,( leaf length + leaf width),( leaf length × leaf width) and leaf mass; there was an extremely significant difference in the correlation coefficients between the leaf mass and some indicators such as Morus alba L. leaf length,leaf width,( leaf length + leaf width),( leaf length × leaf width),petiole transverse diameter in width and petiole mass; there was no significant difference in the correlation coefficients between the leaf mass and the other indicators. The regression analysis was performed on the leaf node and leaf length,leaf width,( leaf length + leaf width),( leaf length × leaf width),( leaf length ÷ leaf width),petiole length,petiole diameter in width,petiole diameter in thickness,petiole mass and leaf mass. Significance F values were0. 4864,0. 1995,0. 2888,0. 3004,0. 2350,0. 2407,0. 8925,0. 5227,0. 7022 and 0. 2000,respectively,that is,there was an extremely significant difference between Morus alba L. leaf node and petiole diameter in width,there was a significant difference between Morus alba L.leaf node and petiole mass,and there was no significant difference between Morus alba L. leaf node and the other indicators. The comparative analysis of quadratic curve regression equation and linear regression equation was performed on some indicators such as leaf length,and it was found that the R value between the leaf node and petiole diameter in width was in line with the logarithmic curve regression equation,and the other R values of quadratic curve regression equation was larger than the other R values of linear regression equation,indicating that different Morus alba L. leaf nodes,leaf length,leaf mass and other indicators were in line with the quadratic curve regression equation. It was concluded that by investigating the leaf node on the Morus alba L. shoots and regression equation,we could predict the leaf size,leaf mass and other indicators,and we could take the leaf node on the Morus alba L. shoots as a main factor affecting the Morus alba L. leaf size and mass.
文摘Lung cancer is the most common cancer worldwide. In the United States, it causes more cancer-related deaths than the next four causes （breast cancer, prostate cancer, colon cancer, and pancreatic cancer） of cancer-related mortality combined （1）. About 30% of people have already progressed to stage III lung cancer and 40% to stage IV at the time they are diagnosed （2）. Although chest X-ray and sputum cytology, when applied in health check-ups, can identify some relatively small tumors, they are not able to lower the overall mortality （3）. More recently,
文摘目的 ：肥胖和乳腺癌密切相关,但其与腋窝淋巴结状态的关系尚不清楚。本文探讨了肥胖与乳腺癌患者腋窝淋巴结状态的相关性。方法：入组306例乳腺癌患者,根据体质指数（body mass index,BMI）分组,回顾性分析患者BMI与肿瘤病理特征,尤其与腋窝淋巴结状态之间的关系。结果：患者平均年龄48岁（范围21~81岁）,平均BMI 25.1,在确诊乳腺癌时54.4%（n=166）的患者BMI正常,45.6%（n=140）的患者BMI≥25。入组患者中,59.6%无腋窝淋巴结转移,40.4%有腋窝淋巴结转移。肥胖组（BMI≥25）腋窝淋巴结切除数量大于正常体重组（BMI〈25.0）,分别为（20.4±11.4）个和（18.1±10.5）个,差异有统计学意义（P〈0.01）。腋窝淋巴结转移的数量在正常体重组、肥胖组分别为（3.15±6.1）、（3.7±6.4）个（P〉0.05）。正常体重组中有、无淋巴结转移的患者比例分别是39.2%和60.8%;肥胖组中分别为41.4%和58.6%（P〉0.05）,有、无淋巴结转移与BMI没有相关性。结论：肥胖乳腺癌患者中切除的腋窝淋巴结数量较正常体重者多,但是发生淋巴结转移的患者比例、淋巴结转移数量与BMI之间均没有相关性。
