The definition and criterion of the Mei symmetry of a relativistic variable mass system are given. The relation between the Mei symmetry and the Noether symmetry of the system is found under infinitesimal transformati...The definition and criterion of the Mei symmetry of a relativistic variable mass system are given. The relation between the Mei symmetry and the Noether symmetry of the system is found under infinitesimal transformations of groups. The conserved quantities to which the Mei symmetry and Noether symmetry of the system lead are obtained.An example is given to illustrate the application of the result.展开更多
The symmetry of Lagrangians of a holonomic variable mass system is studied. Firstly, the differential equations of motion of the system are established. Secondly, the definition and the criterion of the symmetry of th...The symmetry of Lagrangians of a holonomic variable mass system is studied. Firstly, the differential equations of motion of the system are established. Secondly, the definition and the criterion of the symmetry of the system are presented. Thirdly, the conditions under which there exists a conserved quantity deduced by the symmetry are obtained. The form of the conserved quantity is the same as that of the constant mass Lagrange system. Finally, an example is shown to illustrate the application of the result.展开更多
By the theory of symmetries and conserved quantities, the exact invariants and adiabatic invariants of nonholonomic variable mass systems are studied. The perturbation problem of symmetries for the nonholonomic variab...By the theory of symmetries and conserved quantities, the exact invariants and adiabatic invariants of nonholonomic variable mass systems are studied. The perturbation problem of symmetries for the nonholonomic variable mass systems under small excitation is discussed. The concept of high order adiabatic invariant is presented, and the form of exact invariants and adiabatic invariants as well as the conditions for their existence are given. Then the corresponding inverse problem is studied.展开更多
After reviewing the studies on the lateral artificial boundaries in dynamic soil-structure interactions,the free field boundary was theoretically analyzed in asymmetric-and symmetric-matrix forms.First,the lumped mass...After reviewing the studies on the lateral artificial boundaries in dynamic soil-structure interactions,the free field boundary was theoretically analyzed in asymmetric-and symmetric-matrix forms.First,the lumped mass system was combined with viscous or viscoelastic elements to obtain a lumped mass-free field boundary.Second,typical examples were implemented using the finite element software ABAQUS.The incident shear wave was taken to be perpendicular to the bottom to verify the effectiveness of the lumped mass-free field under various sites:underground structures,uniform sites,and layered sites.Finally,the accuracy of the lumped mass-free field boundary was compared with those of the viscoelastic and roller boundaries on different calculation scales,soil damping ratios,structure sizes,and ground motion characteristics.Subsequently,the engineering design values for different damping ratios are given.The results show that the precision of the lumped mass-free field boundary was reasonable,and the operation was simple within the same engineering application.展开更多
Chaotic oscillations are useful in assessing the health of a structure. Hence, simple chaotic systems which can easily be realized mechanically or electro-mechanically are highly desired. We study a new pieeewise line...Chaotic oscillations are useful in assessing the health of a structure. Hence, simple chaotic systems which can easily be realized mechanically or electro-mechanically are highly desired. We study a new pieeewise linear spring-tnass system. The chaotic behaviour in this system is characterized using bifurcation diagrams and the invariant parameters of the dynamics. We also show that there exists a stochastic analogue of this system, which mimics the dynamical features of its deterministic counterpart. This allows a greater flexibility in practical designs as the chaotic oscillations are obtained either deterministically or stochastically. Also, the oscillations are low dimensional, which reduces the computational resources needed for obtaining the invariant parameters of this system.展开更多
The tridiagonal coefficient matrix for the "fixed-fixed" spring-mass system was obtained by changing spring length. And then a new algorithm of the inverse problem was designed to construct the masses and the spring...The tridiagonal coefficient matrix for the "fixed-fixed" spring-mass system was obtained by changing spring length. And then a new algorithm of the inverse problem was designed to construct the masses and the spring constants from the natural frequencies of the "fixed-fixed" and "fixed-fres" spring-mass systems. An example was given to illustrate the results.展开更多
This paper studies Mei symmetry which leads to a generalized Hojman conserved quantity for variable mass systems with unilateral holonomic constraints. The differential equations of motion for the systems are establis...This paper studies Mei symmetry which leads to a generalized Hojman conserved quantity for variable mass systems with unilateral holonomic constraints. The differential equations of motion for the systems are established, the definition and criterion of the Mei symmetry for the systems are given. The necessary and sufficient condition under which the Mei symmetry is a Lie symmetry for the systems is obtained and a generalized Hojman conserved quantity deduced from the Mei symmetry is got. An example is given to illustrate the application of the results.展开更多
BACKGROUND The incidence of chronic kidney disease among patients with diabetes mellitus(DM)remains a global concern.Long-term obesity is known to possibly influence the development of type 2 diabetes mellitus.However...BACKGROUND The incidence of chronic kidney disease among patients with diabetes mellitus(DM)remains a global concern.Long-term obesity is known to possibly influence the development of type 2 diabetes mellitus.However,no previous meta-analysis has assessed the effects of body mass index(BMI)on adverse kidney events in patients with DM.AIM To determine the impact of BMI on adverse kidney events in patients with DM.METHODS A systematic literature search was performed on the PubMed,ISI Web of Science,Scopus,Ovid,Google Scholar,EMBASE,and BMJ databases.We included trials with the following characteristics:(1)Type of study:Prospective,retrospective,randomized,and non-randomized in design;(2)participants:Restricted to patients with DM aged≥18 years;(3)intervention:No intervention;and(4)kidney adverse events:Onset of diabetic kidney disease[estimated glomerular filtration rate(eGFR)of<60 mL/min/1.73 m2 and/or microalbuminuria value of≥30 mg/g Cr],serum creatinine increase of more than double the baseline or end-stage renal disease(eGFR<15 mL/min/1.73 m2 or dialysis),or death.RESULTS Overall,11 studies involving 801 patients with DM were included.High BMI(≥25 kg/m2)was significantly associated with higher blood pressure(BP)[systolic BP by 0.20,95%confidence interval(CI):0.15–0.25,P<0.00001;diastolic BP by 0.21 mmHg,95%CI:0.04–0.37,P=0.010],serum albumin,triglycerides[standard mean difference(SMD)=0.35,95%CI:0.29–0.41,P<0.00001],low-density lipoprotein(SMD=0.12,95%CI:0.04–0.20,P=0.030),and lower high-density lipoprotein(SMD=–0.36,95%CI:–0.51 to–0.21,P<0.00001)in patients with DM compared with those with low BMIs(<25 kg/m2).Our analysis showed that high BMI was associated with a higher risk ratio of adverse kidney events than low BMI(RR:1.22,95%CI:1.01–1.43,P=0.036).CONCLUSION The present analysis suggested that high BMI was a risk factor for adverse kidney events in patients with DM.展开更多
In-site soil flushing and aeration are the typical synergetic remediation technology for contaminated sites.The surfactant present in flushing solutions is bound to affect the aeration efficiency.The purpose of this s...In-site soil flushing and aeration are the typical synergetic remediation technology for contaminated sites.The surfactant present in flushing solutions is bound to affect the aeration efficiency.The purpose of this study is to evaluate the effect of surfactant frequently used in soil flushing on the oxygen mass transfer in micro-nano-bubble(MNB)aeration system.Firstly,bio-surfactants and chemical surfactants were used to investigate their effects on Sauter mean diameter of bubble(dBS),gas holdup(ε),volumetric mass-transfer coefficient(kLa)and liquid-side mass-transfer coefficient(kL)in the MNB aeration system.Then,based upon the experimental results,the Sardeing's and Frossling's models were modified to describe the effect of surfactant on kL in the MNB aeration.The results showed that,for the twenty aqueous surfactant solutions,with the increase in surfactant concentration,the value of dBS,kLa and kL decreased,while the value ofεand gas-liquid interfacial area(a)increased.These phenomena were mainly attributed to the synergistic effects of immobile bubble surface and the suppression of coalescence in the surfactant solutions.In addition,with the presence of electric charge,MNBs in anionic surfactant solutions were smaller and higher in number than in non-ionic surfactant solutions.Furthermore,the accumulation of surfactant on the gas-liquid interface was more conspicuous for small MNB,so the reduction of kL in anionic surfactant solutions was larger than that in non-ionic surfactant solutions.Besides,the modified Frossling's model predicted the effect of surfactant on kL in MNB aeration system with reasonable accuracy.展开更多
In this work,we propose a low-regularity Fourier integrator with almost mass conservation to solve the Davey-StewartsonⅡsystem(hyperbolic-elliptic case).Arbitrary order mass convergence could be achieved by the suita...In this work,we propose a low-regularity Fourier integrator with almost mass conservation to solve the Davey-StewartsonⅡsystem(hyperbolic-elliptic case).Arbitrary order mass convergence could be achieved by the suitable addition of correction terms,while keeping the first order accuracy in H~γ×H^(γ+1)for initial data in H^(γ+1)×H^(γ+1)withγ>1.The main theorem is that,up to some fixed time T,there exist constantsτ_(0)and C depending only on T and‖u‖_(L^(∞)((0,T);H^(γ+1)))such that,for any 0<τ≤τ_(0),we have that‖u(t_(n),·)-u^(n)‖H_γ≤C_(τ),‖v(t_(n),·)-v^(n)‖_(Hγ+1)≤C_(τ),where u^(n)and v^(n)denote the numerical solutions at t_(n)=nτ.Moreover,the mass of the numerical solution M(u^(n))satisfies that|M(u^(n))-M(u_0)|≤Cτ~5.展开更多
Realizing fast and continuous generation of reactive oxygen species(ROSs)via iron-based advanced oxidation processes(AOPs)is significant in the environmental and biological fields.However,current AOPs assisted by co-c...Realizing fast and continuous generation of reactive oxygen species(ROSs)via iron-based advanced oxidation processes(AOPs)is significant in the environmental and biological fields.However,current AOPs assisted by co-catalysts still suffer from the poor mass/electron transfer and non-durable promotion effect,giving rise to the sluggish Fe^(2+)/Fe^(3+)cycle and low dynamic concentration of Fe^(2+)for ROS production.Herein,we present a three-dimensional(3D)macroscale co-catalyst functionalized with molybdenum disulfide(MoS_(2))to achieve ultra-efficient Fe^(2+)regeneration(equilibrium Fe^(2+)ratio of 82.4%)and remarkable stability(more than 20 cycles)via a circulating flow-through process.Unlike the conventional batch-type reactor,experiments and computational fluid dynamics simulations demonstrate that the optimal utilization of the 3D active area under the flow-through mode,initiated by the convectionenhanced mass/charge transfer for Fe^(2+)reduction and then strengthened by MoS_(2)-induced flow rotation for sufficient reactant mixing,is crucial for oxidant activation and subsequent ROS generation.Strikingly,the flow-through co-catalytic system with superwetting capabilities can even tackle the intricate oily wastewater stabilized by different surfactants without the loss of pollutant degradation efficiency.Our findings highlight an innovative co-catalyst system design to expand the applicability of AOPs based technology,especially in large-scale complex wastewater treatment.展开更多
Many cities in the world are aspiring to have a world-class, sustainable public transport system. However, the cost of building new mass transport systems, especially metro projects, is so high it can lead to the post...Many cities in the world are aspiring to have a world-class, sustainable public transport system. However, the cost of building new mass transport systems, especially metro projects, is so high it can lead to the postponement of such projects. New mass transit modes such as Bus Rapid Transit (BRT), Trackless Tram (TT) and suspended systems are continuously emerging. Some of the new emerging modes can deliver high capacity that can be equivalent to Light Rail Transit and Metro Systems but with significantly less cost. This research is meant to develop a comprehensive approach for comparing & assessing several aspects of different mass transit modes. Different research tools, including in-depth literature review, content, and case study analysis, multicriteria assessment, benchmarking and efficiency analysis, are used to reach conclusions for optimum mass transit options from different perspectives.展开更多
Background: The differential diagnosis for intracavitary cardiac masses is limited, typically including vegetations, tumors, or thrombi. Cardiac thrombi can often mimic cardiac tumors on imaging, creating a diagnostic...Background: The differential diagnosis for intracavitary cardiac masses is limited, typically including vegetations, tumors, or thrombi. Cardiac thrombi can often mimic cardiac tumors on imaging, creating a diagnostic challenge. Primary cardiac tumors are rare and usually benign, whereas most cardiac tumors result from metastases, commonly originating from malignancies in the breast, lung, or melanoma. Aim: This report highlights the importance of distinguishing various cardiac masses based on clinical presentations, clinical courses, and radiological features. Case Presentation: We describe two cases of cardiac masses with unique and diverse clinical features. Each case posed significant diagnostic challenges due to their distinct presentations and clinical progressions. Conclusion: These cases underscore the importance of considering both benign and metastatic origins in the differential diagnosis of intracavitary cardiac masses. Accurate differentiation between thrombi and tumors is crucial for appropriate management and treatment.展开更多
The protein connector enhancer of kinase suppressor of Ras 2(CNKSR2),present in both the postsynaptic density and cytoplasm of neurons,is a scaffolding protein with several protein-binding domains.Variants of the CNKS...The protein connector enhancer of kinase suppressor of Ras 2(CNKSR2),present in both the postsynaptic density and cytoplasm of neurons,is a scaffolding protein with several protein-binding domains.Variants of the CNKSR2 gene have been implicated in neurodevelopmental disorders,particularly intellectual disability,although the precise mechanism involved has not yet been fully understood.Research has demonstrated that CNKSR2 plays a role in facilitating the localization of postsynaptic density protein complexes to the membrane,thereby influencing synaptic signaling and the morphogenesis of dendritic spines.However,the function of CNKSR2 in the cytoplasm remains to be elucidated.In this study,we used immunoprecipitation and high-resolution liquid chromatography-mass spectrometry to identify the interactors of CNKSR2.Through a combination of bioinformatic analysis and cytological experiments,we found that the CNKSR2 interactors were significantly enriched in the proteome of the centrosome.We also showed that CNKSR2 interacted with the microtubule protein DYNC1H1 and with the centrosome marker CEP290.Subsequent colocalization analysis confirmed the centrosomal localization of CNKSR2.When we downregulated CNKSR2 expression in mouse neuroblastoma cells(Neuro 2A),we observed significant changes in the expression of numerous centrosomal genes.This manipulation also affected centrosome-related functions,including cell size and shape,cell proliferation,and motility.Furthermore,we found that CNKSR2 interactors were highly enriched in de novo variants associated with intellectual disability and autism spectrum disorder.Our findings establish a connection between CNKSR2 and the centrosome,and offer new insights into the underlying mechanisms of neurodevelopmental disorders.展开更多
The differential equations of motion of a comtlaint system with parameters and variable mass, of a system with variable mass and servo constraints and those for the control problem on the forced motion of constraint s...The differential equations of motion of a comtlaint system with parameters and variable mass, of a system with variable mass and servo constraints and those for the control problem on the forced motion of constraint systems with variable mass are given respectively. Finally, an example is presented.展开更多
Cystic lesions of the anterior mediastinum in children suggest a well-known group of benign lesions that are comparatively frequent.Thymic cysts(TCs)are mostly positioned in the anterior mediastinum and some patients ...Cystic lesions of the anterior mediastinum in children suggest a well-known group of benign lesions that are comparatively frequent.Thymic cysts(TCs)are mostly positioned in the anterior mediastinum and some patients in the neck.Benign TCs classified as congenital intra-thoracic mesothelial cysts are commonly asymptomatic and have slight clinical significance.Multilocular TC,which can mimic another anterior mediastinal cystic tumor and is seen in adults,is more clinically important.It is a sporadic mediastinal lesion thought to arise in the course of acquired inflammation.Congenital mediastinal cysts represent 3%-6%of all mediastinal tumors and 10%-18%of radiologically reported mediastinal masses.Mediastinal TCs are uncommon and it is hard to know their true incidence.About 60%of cases with mediastinal TCs are asymptomatic,and the remainder of patients complains of nonspecific symptoms(e.g.,chest pain,dyspnea,or cough).The literature suggests that most cysts are benign,but an indefinite percentage may have a neoplastic process and result in significant compressive symptoms over time.Clinical symptoms of TCs vary depending on the location.In addition,frequent symptoms at the appearance of enlarged benign thymic and mediastinal cysts generally contain compressive symptoms(e.g.,respiratory distress,thymic pain,and symptoms related to Horner syndrome,hoarseness,dysphonia,dyspnea,orthopnea,wheezing,and fever).Many TCs have cystic density and a neat border and are simple to diagnose with radiological imaging.However,some TCs are hard to identify before surgery and may be misidentified as thymomas depending on their site and computed tomography results.Excision by thoracotomy,median sternotomy,or video-assisted techniques is essential for conclusive diagnosis,management,and abolition of relapse of anterior mediastinal masses and TCs.Histopathologic examination may be required after surgery.Considering the extent of the mass and the preliminary inability to make a definitive diagnosis,en bloc excision of the cyst was thought to be preferred to circumvent likely complications(e.g.,perforation,spillage of the contents,or incomplete excision).展开更多
This paper studies the Lie symmetries and Noether conserved quantities of discrete mechanical systems with variable mass. The discrete Euler-Lagrange equation and energy evolution equation are derived by using a total...This paper studies the Lie symmetries and Noether conserved quantities of discrete mechanical systems with variable mass. The discrete Euler-Lagrange equation and energy evolution equation are derived by using a total variational principle. The invariance of discrete equations under infinitesimal transformation groups is defined to be Lie symmetry. The condition of obtaining the Noether conserved quantities from the Lie symmetries is also presented. An example is discussed for applications of the results.展开更多
The research on water masses is always one important facet of Oceanography. I adopt the method of Fuzzy Density Clustering to analyse water masses. Meanwhile, I use Visual Basic 6.0 as developing platform and utilize ...The research on water masses is always one important facet of Oceanography. I adopt the method of Fuzzy Density Clustering to analyse water masses. Meanwhile, I use Visual Basic 6.0 as developing platform and utilize the MapX components to develop the platform of GIS. By integrating the Water Masses Model compiled by FORTRAN language, and GIS using Tight Coupling, I develop an Integrated System. That makes all phases are finished in one condition, including the gain of computing grid, the pick-up and analysis of data, the choice of parameters and resetting, the computing of model, and the result's visualization. It improves the efficiency of the data analysis and decision-making Finally, this system is applied in the Zhoushan fishing ground and adjacent region. The results are satisfying.展开更多
This paper presents the generalized principles of least action of variable mass nonholonomic nonconservative system in noninertial reference frame, proves the equivalence between Holder form and Suslov form, and then ...This paper presents the generalized principles of least action of variable mass nonholonomic nonconservative system in noninertial reference frame, proves the equivalence between Holder form and Suslov form, and then obtains differential equations of motion of variable mass nonholonomic nonconservative system in noninertial reference frame.展开更多
In this paper, the integration methods of dynamics equations of relative motion of variable mass nonlinear nonholonomic system are given such as the gradient method, the single-component method and the field method. F...In this paper, the integration methods of dynamics equations of relative motion of variable mass nonlinear nonholonomic system are given such as the gradient method, the single-component method and the field method. Firstly, the dynamics equations are written in the canonical form and the field form. Secondly, the gradient method, the single-component method and the field method are used to integrate the dynamics equations of the corresponding constant mass holonomic system in inertial reference frame respectively. With the restriction of nonholonomic constraints to the initial conditions being considered, the solutions of the dynamics equations of variable mass nonlinear nonholonomic system in noninertial reference frame are obtained.展开更多
文摘The definition and criterion of the Mei symmetry of a relativistic variable mass system are given. The relation between the Mei symmetry and the Noether symmetry of the system is found under infinitesimal transformations of groups. The conserved quantities to which the Mei symmetry and Noether symmetry of the system lead are obtained.An example is given to illustrate the application of the result.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 10932002 and 10972031)the Beijing Municipal Key Disciplines Fund for General Mechanics and Foundation of Mechanics
文摘The symmetry of Lagrangians of a holonomic variable mass system is studied. Firstly, the differential equations of motion of the system are established. Secondly, the definition and the criterion of the symmetry of the system are presented. Thirdly, the conditions under which there exists a conserved quantity deduced by the symmetry are obtained. The form of the conserved quantity is the same as that of the constant mass Lagrange system. Finally, an example is shown to illustrate the application of the result.
文摘By the theory of symmetries and conserved quantities, the exact invariants and adiabatic invariants of nonholonomic variable mass systems are studied. The perturbation problem of symmetries for the nonholonomic variable mass systems under small excitation is discussed. The concept of high order adiabatic invariant is presented, and the form of exact invariants and adiabatic invariants as well as the conditions for their existence are given. Then the corresponding inverse problem is studied.
基金Natural Science Foundation of Henan Province under Grant No.222300420415。
文摘After reviewing the studies on the lateral artificial boundaries in dynamic soil-structure interactions,the free field boundary was theoretically analyzed in asymmetric-and symmetric-matrix forms.First,the lumped mass system was combined with viscous or viscoelastic elements to obtain a lumped mass-free field boundary.Second,typical examples were implemented using the finite element software ABAQUS.The incident shear wave was taken to be perpendicular to the bottom to verify the effectiveness of the lumped mass-free field under various sites:underground structures,uniform sites,and layered sites.Finally,the accuracy of the lumped mass-free field boundary was compared with those of the viscoelastic and roller boundaries on different calculation scales,soil damping ratios,structure sizes,and ground motion characteristics.Subsequently,the engineering design values for different damping ratios are given.The results show that the precision of the lumped mass-free field boundary was reasonable,and the operation was simple within the same engineering application.
基金the Council of Scientific and Industrial Research(CSIR),New Delhi for Financial Support through a Senior Research Fellowship(SRF)
文摘Chaotic oscillations are useful in assessing the health of a structure. Hence, simple chaotic systems which can easily be realized mechanically or electro-mechanically are highly desired. We study a new pieeewise linear spring-tnass system. The chaotic behaviour in this system is characterized using bifurcation diagrams and the invariant parameters of the dynamics. We also show that there exists a stochastic analogue of this system, which mimics the dynamical features of its deterministic counterpart. This allows a greater flexibility in practical designs as the chaotic oscillations are obtained either deterministically or stochastically. Also, the oscillations are low dimensional, which reduces the computational resources needed for obtaining the invariant parameters of this system.
基金Project supported by the National Natural Science Foundation of China(Grant No.10271074)
文摘The tridiagonal coefficient matrix for the "fixed-fixed" spring-mass system was obtained by changing spring length. And then a new algorithm of the inverse problem was designed to construct the masses and the spring constants from the natural frequencies of the "fixed-fixed" and "fixed-fres" spring-mass systems. An example was given to illustrate the results.
文摘This paper studies Mei symmetry which leads to a generalized Hojman conserved quantity for variable mass systems with unilateral holonomic constraints. The differential equations of motion for the systems are established, the definition and criterion of the Mei symmetry for the systems are given. The necessary and sufficient condition under which the Mei symmetry is a Lie symmetry for the systems is obtained and a generalized Hojman conserved quantity deduced from the Mei symmetry is got. An example is given to illustrate the application of the results.
基金Supported by Special Project for Improving Science and Technology Innovation Ability of Army Medical University,No.2022XLC09.
文摘BACKGROUND The incidence of chronic kidney disease among patients with diabetes mellitus(DM)remains a global concern.Long-term obesity is known to possibly influence the development of type 2 diabetes mellitus.However,no previous meta-analysis has assessed the effects of body mass index(BMI)on adverse kidney events in patients with DM.AIM To determine the impact of BMI on adverse kidney events in patients with DM.METHODS A systematic literature search was performed on the PubMed,ISI Web of Science,Scopus,Ovid,Google Scholar,EMBASE,and BMJ databases.We included trials with the following characteristics:(1)Type of study:Prospective,retrospective,randomized,and non-randomized in design;(2)participants:Restricted to patients with DM aged≥18 years;(3)intervention:No intervention;and(4)kidney adverse events:Onset of diabetic kidney disease[estimated glomerular filtration rate(eGFR)of<60 mL/min/1.73 m2 and/or microalbuminuria value of≥30 mg/g Cr],serum creatinine increase of more than double the baseline or end-stage renal disease(eGFR<15 mL/min/1.73 m2 or dialysis),or death.RESULTS Overall,11 studies involving 801 patients with DM were included.High BMI(≥25 kg/m2)was significantly associated with higher blood pressure(BP)[systolic BP by 0.20,95%confidence interval(CI):0.15–0.25,P<0.00001;diastolic BP by 0.21 mmHg,95%CI:0.04–0.37,P=0.010],serum albumin,triglycerides[standard mean difference(SMD)=0.35,95%CI:0.29–0.41,P<0.00001],low-density lipoprotein(SMD=0.12,95%CI:0.04–0.20,P=0.030),and lower high-density lipoprotein(SMD=–0.36,95%CI:–0.51 to–0.21,P<0.00001)in patients with DM compared with those with low BMIs(<25 kg/m2).Our analysis showed that high BMI was associated with a higher risk ratio of adverse kidney events than low BMI(RR:1.22,95%CI:1.01–1.43,P=0.036).CONCLUSION The present analysis suggested that high BMI was a risk factor for adverse kidney events in patients with DM.
基金financially supported by the National Natural Science Foundation of China(41877240)National Key Research and Development Program of China(2018YFC1802300)Scientific Research Foundation of Graduate School of Southeast University(YBPY2154).
文摘In-site soil flushing and aeration are the typical synergetic remediation technology for contaminated sites.The surfactant present in flushing solutions is bound to affect the aeration efficiency.The purpose of this study is to evaluate the effect of surfactant frequently used in soil flushing on the oxygen mass transfer in micro-nano-bubble(MNB)aeration system.Firstly,bio-surfactants and chemical surfactants were used to investigate their effects on Sauter mean diameter of bubble(dBS),gas holdup(ε),volumetric mass-transfer coefficient(kLa)and liquid-side mass-transfer coefficient(kL)in the MNB aeration system.Then,based upon the experimental results,the Sardeing's and Frossling's models were modified to describe the effect of surfactant on kL in the MNB aeration.The results showed that,for the twenty aqueous surfactant solutions,with the increase in surfactant concentration,the value of dBS,kLa and kL decreased,while the value ofεand gas-liquid interfacial area(a)increased.These phenomena were mainly attributed to the synergistic effects of immobile bubble surface and the suppression of coalescence in the surfactant solutions.In addition,with the presence of electric charge,MNBs in anionic surfactant solutions were smaller and higher in number than in non-ionic surfactant solutions.Furthermore,the accumulation of surfactant on the gas-liquid interface was more conspicuous for small MNB,so the reduction of kL in anionic surfactant solutions was larger than that in non-ionic surfactant solutions.Besides,the modified Frossling's model predicted the effect of surfactant on kL in MNB aeration system with reasonable accuracy.
基金supported by the NSFC(11901120)supported by the NSFC(12171356)the Science and Technology Program of Guangzhou,China(2024A04J4027)。
文摘In this work,we propose a low-regularity Fourier integrator with almost mass conservation to solve the Davey-StewartsonⅡsystem(hyperbolic-elliptic case).Arbitrary order mass convergence could be achieved by the suitable addition of correction terms,while keeping the first order accuracy in H~γ×H^(γ+1)for initial data in H^(γ+1)×H^(γ+1)withγ>1.The main theorem is that,up to some fixed time T,there exist constantsτ_(0)and C depending only on T and‖u‖_(L^(∞)((0,T);H^(γ+1)))such that,for any 0<τ≤τ_(0),we have that‖u(t_(n),·)-u^(n)‖H_γ≤C_(τ),‖v(t_(n),·)-v^(n)‖_(Hγ+1)≤C_(τ),where u^(n)and v^(n)denote the numerical solutions at t_(n)=nτ.Moreover,the mass of the numerical solution M(u^(n))satisfies that|M(u^(n))-M(u_0)|≤Cτ~5.
基金supported by National Natural Science Foundation of China(52003240)Zhejiang Provincial Natural Science Foundation of China(LQ21B070007)China Postdoctoral Science Foundation(2022M722818).
文摘Realizing fast and continuous generation of reactive oxygen species(ROSs)via iron-based advanced oxidation processes(AOPs)is significant in the environmental and biological fields.However,current AOPs assisted by co-catalysts still suffer from the poor mass/electron transfer and non-durable promotion effect,giving rise to the sluggish Fe^(2+)/Fe^(3+)cycle and low dynamic concentration of Fe^(2+)for ROS production.Herein,we present a three-dimensional(3D)macroscale co-catalyst functionalized with molybdenum disulfide(MoS_(2))to achieve ultra-efficient Fe^(2+)regeneration(equilibrium Fe^(2+)ratio of 82.4%)and remarkable stability(more than 20 cycles)via a circulating flow-through process.Unlike the conventional batch-type reactor,experiments and computational fluid dynamics simulations demonstrate that the optimal utilization of the 3D active area under the flow-through mode,initiated by the convectionenhanced mass/charge transfer for Fe^(2+)reduction and then strengthened by MoS_(2)-induced flow rotation for sufficient reactant mixing,is crucial for oxidant activation and subsequent ROS generation.Strikingly,the flow-through co-catalytic system with superwetting capabilities can even tackle the intricate oily wastewater stabilized by different surfactants without the loss of pollutant degradation efficiency.Our findings highlight an innovative co-catalyst system design to expand the applicability of AOPs based technology,especially in large-scale complex wastewater treatment.
文摘Many cities in the world are aspiring to have a world-class, sustainable public transport system. However, the cost of building new mass transport systems, especially metro projects, is so high it can lead to the postponement of such projects. New mass transit modes such as Bus Rapid Transit (BRT), Trackless Tram (TT) and suspended systems are continuously emerging. Some of the new emerging modes can deliver high capacity that can be equivalent to Light Rail Transit and Metro Systems but with significantly less cost. This research is meant to develop a comprehensive approach for comparing & assessing several aspects of different mass transit modes. Different research tools, including in-depth literature review, content, and case study analysis, multicriteria assessment, benchmarking and efficiency analysis, are used to reach conclusions for optimum mass transit options from different perspectives.
文摘Background: The differential diagnosis for intracavitary cardiac masses is limited, typically including vegetations, tumors, or thrombi. Cardiac thrombi can often mimic cardiac tumors on imaging, creating a diagnostic challenge. Primary cardiac tumors are rare and usually benign, whereas most cardiac tumors result from metastases, commonly originating from malignancies in the breast, lung, or melanoma. Aim: This report highlights the importance of distinguishing various cardiac masses based on clinical presentations, clinical courses, and radiological features. Case Presentation: We describe two cases of cardiac masses with unique and diverse clinical features. Each case posed significant diagnostic challenges due to their distinct presentations and clinical progressions. Conclusion: These cases underscore the importance of considering both benign and metastatic origins in the differential diagnosis of intracavitary cardiac masses. Accurate differentiation between thrombi and tumors is crucial for appropriate management and treatment.
基金supported by the National Nature Science Foundation of China,No.32101020(to JL)the Natural Science Foundation of Shandong Province,Nos.ZR2020MC071(to JL),ZR2023MH327(to HZ)+1 种基金the Integrated Project of Major Research Plan of National Natural Science Foundation of China,No.92249303(to PL)the Natural Science Foundation of Qingdao,No.23-2-1-193-zyyd-jch(to HZ)。
文摘The protein connector enhancer of kinase suppressor of Ras 2(CNKSR2),present in both the postsynaptic density and cytoplasm of neurons,is a scaffolding protein with several protein-binding domains.Variants of the CNKSR2 gene have been implicated in neurodevelopmental disorders,particularly intellectual disability,although the precise mechanism involved has not yet been fully understood.Research has demonstrated that CNKSR2 plays a role in facilitating the localization of postsynaptic density protein complexes to the membrane,thereby influencing synaptic signaling and the morphogenesis of dendritic spines.However,the function of CNKSR2 in the cytoplasm remains to be elucidated.In this study,we used immunoprecipitation and high-resolution liquid chromatography-mass spectrometry to identify the interactors of CNKSR2.Through a combination of bioinformatic analysis and cytological experiments,we found that the CNKSR2 interactors were significantly enriched in the proteome of the centrosome.We also showed that CNKSR2 interacted with the microtubule protein DYNC1H1 and with the centrosome marker CEP290.Subsequent colocalization analysis confirmed the centrosomal localization of CNKSR2.When we downregulated CNKSR2 expression in mouse neuroblastoma cells(Neuro 2A),we observed significant changes in the expression of numerous centrosomal genes.This manipulation also affected centrosome-related functions,including cell size and shape,cell proliferation,and motility.Furthermore,we found that CNKSR2 interactors were highly enriched in de novo variants associated with intellectual disability and autism spectrum disorder.Our findings establish a connection between CNKSR2 and the centrosome,and offer new insights into the underlying mechanisms of neurodevelopmental disorders.
文摘The differential equations of motion of a comtlaint system with parameters and variable mass, of a system with variable mass and servo constraints and those for the control problem on the forced motion of constraint systems with variable mass are given respectively. Finally, an example is presented.
文摘Cystic lesions of the anterior mediastinum in children suggest a well-known group of benign lesions that are comparatively frequent.Thymic cysts(TCs)are mostly positioned in the anterior mediastinum and some patients in the neck.Benign TCs classified as congenital intra-thoracic mesothelial cysts are commonly asymptomatic and have slight clinical significance.Multilocular TC,which can mimic another anterior mediastinal cystic tumor and is seen in adults,is more clinically important.It is a sporadic mediastinal lesion thought to arise in the course of acquired inflammation.Congenital mediastinal cysts represent 3%-6%of all mediastinal tumors and 10%-18%of radiologically reported mediastinal masses.Mediastinal TCs are uncommon and it is hard to know their true incidence.About 60%of cases with mediastinal TCs are asymptomatic,and the remainder of patients complains of nonspecific symptoms(e.g.,chest pain,dyspnea,or cough).The literature suggests that most cysts are benign,but an indefinite percentage may have a neoplastic process and result in significant compressive symptoms over time.Clinical symptoms of TCs vary depending on the location.In addition,frequent symptoms at the appearance of enlarged benign thymic and mediastinal cysts generally contain compressive symptoms(e.g.,respiratory distress,thymic pain,and symptoms related to Horner syndrome,hoarseness,dysphonia,dyspnea,orthopnea,wheezing,and fever).Many TCs have cystic density and a neat border and are simple to diagnose with radiological imaging.However,some TCs are hard to identify before surgery and may be misidentified as thymomas depending on their site and computed tomography results.Excision by thoracotomy,median sternotomy,or video-assisted techniques is essential for conclusive diagnosis,management,and abolition of relapse of anterior mediastinal masses and TCs.Histopathologic examination may be required after surgery.Considering the extent of the mass and the preliminary inability to make a definitive diagnosis,en bloc excision of the cyst was thought to be preferred to circumvent likely complications(e.g.,perforation,spillage of the contents,or incomplete excision).
基金Project supported by the National Natural Science Foundation of China(Grant No10672143)
文摘This paper studies the Lie symmetries and Noether conserved quantities of discrete mechanical systems with variable mass. The discrete Euler-Lagrange equation and energy evolution equation are derived by using a total variational principle. The invariance of discrete equations under infinitesimal transformation groups is defined to be Lie symmetry. The condition of obtaining the Noether conserved quantities from the Lie symmetries is also presented. An example is discussed for applications of the results.
文摘The research on water masses is always one important facet of Oceanography. I adopt the method of Fuzzy Density Clustering to analyse water masses. Meanwhile, I use Visual Basic 6.0 as developing platform and utilize the MapX components to develop the platform of GIS. By integrating the Water Masses Model compiled by FORTRAN language, and GIS using Tight Coupling, I develop an Integrated System. That makes all phases are finished in one condition, including the gain of computing grid, the pick-up and analysis of data, the choice of parameters and resetting, the computing of model, and the result's visualization. It improves the efficiency of the data analysis and decision-making Finally, this system is applied in the Zhoushan fishing ground and adjacent region. The results are satisfying.
文摘This paper presents the generalized principles of least action of variable mass nonholonomic nonconservative system in noninertial reference frame, proves the equivalence between Holder form and Suslov form, and then obtains differential equations of motion of variable mass nonholonomic nonconservative system in noninertial reference frame.
文摘In this paper, the integration methods of dynamics equations of relative motion of variable mass nonlinear nonholonomic system are given such as the gradient method, the single-component method and the field method. Firstly, the dynamics equations are written in the canonical form and the field form. Secondly, the gradient method, the single-component method and the field method are used to integrate the dynamics equations of the corresponding constant mass holonomic system in inertial reference frame respectively. With the restriction of nonholonomic constraints to the initial conditions being considered, the solutions of the dynamics equations of variable mass nonlinear nonholonomic system in noninertial reference frame are obtained.