The Northeast United States spring is indicative of major meteorological and biological change though the seasonal boundaries are difficult to define and may even be changing with global climate warming. This research...The Northeast United States spring is indicative of major meteorological and biological change though the seasonal boundaries are difficult to define and may even be changing with global climate warming. This research aims to obtain a synoptic meteorological definition of the spring season through an assessment of air mass frequency over the past 60 years. The validity of recent speculations that the onset and termination of spring have changed in recent decades with global change is also examined. The Spatial Synoptic Classification is utilized to define daily air masses over the region. Annual and seasonal baseline frequencies are identified and their differences are acquired to characterize the season. Seasonal frequency departures of the early and late segments of the period of record are calculated and examined for practical and statistical significance. The daily boundaries of early and late spring are also isolated and assessed across the period of record to identify important changes in the season’s initiation and termination through time. Results indicate that the Northeast spring season is dominated by dry air masses, mainly the Dry Moderate and Dry Polar types. Prior to 1975, more polar air masses are detected while after 1975 more moderate and tropical types are identified. Late spring is characterized by increased variability in all moist air mass frequencies. These findings indicate that, from a synoptic perspective, the season is dry through time but modern springs are also warmer than those of past decades and the initiation of the season is likely arriving earlier. The end of the season represents more variable day-to-day air mass conditions in modern times than detected in past decades.展开更多
Product customization has been recognized as an effective means to implement mass cus-tomization (MC). A new theory and method for MC-oriented evolutionary design of configuration product is presented based on the s...Product customization has been recognized as an effective means to implement mass cus-tomization (MC). A new theory and method for MC-oriented evolutionary design of configuration product is presented based on the study of developing law of evolutionary design in integrated envi-ronment, which focuses on the innovation and reuse properties of configuration product. The key technologies for general requirement modeling in quick response to customer requirement, multi-level stepwise configuration optimization driven by customer requirement and evolutionary deduction of product variable structure based on configuration association are thoroughly investigated. The suc-cessful application of the presented method in the development of real-life products demonstrates its utility, flexibility and robusticity.展开更多
Based on single drop mass transfer models and two phase flow equation,a general equationfor calculating the‘true’height of transfer unit of extraction columns was derived and tested withfour types of extraction colu...Based on single drop mass transfer models and two phase flow equation,a general equationfor calculating the‘true’height of transfer unit of extraction columns was derived and tested withfour types of extraction columns with some different working systems.The calculated results fittedwell with those obtained by experiments.展开更多
With the latest advances in computing technology, a huge amount of efforts have gone into simulation of a range of scientific phenomena in engineering fields. One such case is the simulation of heat and mass transfer ...With the latest advances in computing technology, a huge amount of efforts have gone into simulation of a range of scientific phenomena in engineering fields. One such case is the simulation of heat and mass transfer in capillary porous media, which is becoming more and more necessary in analyzing a number of eventualities in science and engineering applications. However, this procedure of numerical solution of heat and mass transfer equations for capillary porous media is very time consuming. Therefore, this paper pursuit is at making use of one of the acceleration methods developed in the graphics community that exploits a graphical processing unit (GPU), which is applied to the numerical solutions of such heat and mass transfer equations. The nVidia Compute Unified Device Architecture (CUDA) programming model offers a correct approach of applying parallel computing to applications with graphical processing unit. This paper suggests a true improvement in the performance while solving the heat and mass transfer equations for capillary porous radially composite cylinder with the first type of boundary conditions. This heat and mass transfer simulation is carried out through the usage of CUDA platform on nVidia Quadro FX 4800 graphics card. Our experimental outcomes exhibit the drastic overall performance enhancement when GPU is used to illustrate heat and mass transfer simulation. GPU can considerably accelerate the performance with a maximum found speedup of more than 5-fold times. Therefore, the GPU is a good strategy to accelerate the heat and mass transfer simulation in porous media.展开更多
With the recent developments in computing technology, increased efforts have gone into simulation of various scientific methods and phenomenon in engineering fields. One such case is the simulation of heat and mass tr...With the recent developments in computing technology, increased efforts have gone into simulation of various scientific methods and phenomenon in engineering fields. One such case is the simulation of heat and mass transfer in capillary porous media, which is becoming more and more important in analysing various scenarios in engineering applications. Analysing such heat and mass transfer phenomenon in a given environment requires us to simulate it. This entails simulation of coupled heat mass transfer equations. However, this process of numerical solution of heat and mass transfer equations is very much time consuming. Therefore, this paper aims at utilizing one of the acceleration techniques developed in the graphics community that exploits a graphics processing unit (GPU) which is applied to the numerical solutions of heat and mass transfer equations. The nVidia Compute Unified Device Architecture (CUDA) programming model caters a good method of applying parallel computing to program the graphical processing unit. This paper shows a good improvement in the performance while solving the heat and mass transfer equations for capillary porous composite cylinder with the second kind of boundary conditions numerically running on GPU. This heat and mass transfer simulation is implemented using CUDA platform on nVidia Quadro FX 4800 graphics card. Our experimental results depict the drastic performance improvement when GPU is used to perform heat and mass transfer simulation. GPU can significantly accelerate the performance with a maximum observed speedup of more than 7-fold times. Therefore, the GPU is a good approach to accelerate the heat and mass transfer simulation.展开更多
目的探讨串联质谱(tandem mass spectrometry,MS/MS)联合气相质谱(gas phase mass spectrometry,GC-MS)在新生儿重症监护病房(neonatal intensive care unit,NICU)遗传代谢病(inherited metabolic disorders,IMD)筛查诊断中的应用价值...目的探讨串联质谱(tandem mass spectrometry,MS/MS)联合气相质谱(gas phase mass spectrometry,GC-MS)在新生儿重症监护病房(neonatal intensive care unit,NICU)遗传代谢病(inherited metabolic disorders,IMD)筛查诊断中的应用价值。方法选取2020年1月至2021年12月解放军总医院第七医学中心NICU收治的3682例新生儿(其中足月儿1794例,早产儿1888例)为观察对象,采集干血斑行MS/MS遗传代谢病筛查。初次筛查阳性者重新采样复查并行尿液GC-MS检测。根据患儿代谢谱结合临床表现进行生化诊断。统计学方法采用χ^(2)检验。结果3682例NICU患儿中初筛阳性率为5.65%(208/3682),复筛阳性率为1.33%(49/3682),共生化诊断IMD患儿14例,总检出率为0.38%(14/3682),其中足月儿检出率高于早产儿[0.67%(12/1794)与0.11%(2/1888),χ^(2)=7.697,P=0.006]。14例IMD中,有机酸代谢异常11例,包括甲基丙二酸血症8例(57.1%)、戊二酸血症2例(14.3%)、3-甲基戊二烯酸尿症1例(7.1%);氨基酸代谢异常3例,包括尿素循环障碍2例(14.3%)、高苯丙氨酸血症1例(7.1%)。MS/MS初筛假阳性率为5.29%(194/3668),阳性预测值为6.73%(14/208)。召回复查后,二次MS/MS复测,假阳性率为0.95%(35/3668),阳性预测值为28.57%(14/49)。在各类MS/MS指标异常中,丙酰肉碱及其比值增高、戊二酰肉碱增高的阳性预测值高于氨基酸类代谢异常。结论NICU人群IMD发病率较高,且存在早产、感染等多种非遗传因素,干扰MS/MS代谢筛查结果。及时进行MS/MS复查及尿GC-MS分析可以提高诊断效率,明确生化诊断。展开更多
文摘The Northeast United States spring is indicative of major meteorological and biological change though the seasonal boundaries are difficult to define and may even be changing with global climate warming. This research aims to obtain a synoptic meteorological definition of the spring season through an assessment of air mass frequency over the past 60 years. The validity of recent speculations that the onset and termination of spring have changed in recent decades with global change is also examined. The Spatial Synoptic Classification is utilized to define daily air masses over the region. Annual and seasonal baseline frequencies are identified and their differences are acquired to characterize the season. Seasonal frequency departures of the early and late segments of the period of record are calculated and examined for practical and statistical significance. The daily boundaries of early and late spring are also isolated and assessed across the period of record to identify important changes in the season’s initiation and termination through time. Results indicate that the Northeast spring season is dominated by dry air masses, mainly the Dry Moderate and Dry Polar types. Prior to 1975, more polar air masses are detected while after 1975 more moderate and tropical types are identified. Late spring is characterized by increased variability in all moist air mass frequencies. These findings indicate that, from a synoptic perspective, the season is dry through time but modern springs are also warmer than those of past decades and the initiation of the season is likely arriving earlier. The end of the season represents more variable day-to-day air mass conditions in modern times than detected in past decades.
基金This project is supported by National Natural Science Foundation of China (No. 50505044, No. 60573175)Postdoctoral Foundation of China (No. 2005037816).
文摘Product customization has been recognized as an effective means to implement mass cus-tomization (MC). A new theory and method for MC-oriented evolutionary design of configuration product is presented based on the study of developing law of evolutionary design in integrated envi-ronment, which focuses on the innovation and reuse properties of configuration product. The key technologies for general requirement modeling in quick response to customer requirement, multi-level stepwise configuration optimization driven by customer requirement and evolutionary deduction of product variable structure based on configuration association are thoroughly investigated. The suc-cessful application of the presented method in the development of real-life products demonstrates its utility, flexibility and robusticity.
基金Supported by the National Natural Science Foundation of China.
文摘Based on single drop mass transfer models and two phase flow equation,a general equationfor calculating the‘true’height of transfer unit of extraction columns was derived and tested withfour types of extraction columns with some different working systems.The calculated results fittedwell with those obtained by experiments.
文摘With the latest advances in computing technology, a huge amount of efforts have gone into simulation of a range of scientific phenomena in engineering fields. One such case is the simulation of heat and mass transfer in capillary porous media, which is becoming more and more necessary in analyzing a number of eventualities in science and engineering applications. However, this procedure of numerical solution of heat and mass transfer equations for capillary porous media is very time consuming. Therefore, this paper pursuit is at making use of one of the acceleration methods developed in the graphics community that exploits a graphical processing unit (GPU), which is applied to the numerical solutions of such heat and mass transfer equations. The nVidia Compute Unified Device Architecture (CUDA) programming model offers a correct approach of applying parallel computing to applications with graphical processing unit. This paper suggests a true improvement in the performance while solving the heat and mass transfer equations for capillary porous radially composite cylinder with the first type of boundary conditions. This heat and mass transfer simulation is carried out through the usage of CUDA platform on nVidia Quadro FX 4800 graphics card. Our experimental outcomes exhibit the drastic overall performance enhancement when GPU is used to illustrate heat and mass transfer simulation. GPU can considerably accelerate the performance with a maximum found speedup of more than 5-fold times. Therefore, the GPU is a good strategy to accelerate the heat and mass transfer simulation in porous media.
文摘With the recent developments in computing technology, increased efforts have gone into simulation of various scientific methods and phenomenon in engineering fields. One such case is the simulation of heat and mass transfer in capillary porous media, which is becoming more and more important in analysing various scenarios in engineering applications. Analysing such heat and mass transfer phenomenon in a given environment requires us to simulate it. This entails simulation of coupled heat mass transfer equations. However, this process of numerical solution of heat and mass transfer equations is very much time consuming. Therefore, this paper aims at utilizing one of the acceleration techniques developed in the graphics community that exploits a graphics processing unit (GPU) which is applied to the numerical solutions of heat and mass transfer equations. The nVidia Compute Unified Device Architecture (CUDA) programming model caters a good method of applying parallel computing to program the graphical processing unit. This paper shows a good improvement in the performance while solving the heat and mass transfer equations for capillary porous composite cylinder with the second kind of boundary conditions numerically running on GPU. This heat and mass transfer simulation is implemented using CUDA platform on nVidia Quadro FX 4800 graphics card. Our experimental results depict the drastic performance improvement when GPU is used to perform heat and mass transfer simulation. GPU can significantly accelerate the performance with a maximum observed speedup of more than 7-fold times. Therefore, the GPU is a good approach to accelerate the heat and mass transfer simulation.
文摘目的探讨串联质谱(tandem mass spectrometry,MS/MS)联合气相质谱(gas phase mass spectrometry,GC-MS)在新生儿重症监护病房(neonatal intensive care unit,NICU)遗传代谢病(inherited metabolic disorders,IMD)筛查诊断中的应用价值。方法选取2020年1月至2021年12月解放军总医院第七医学中心NICU收治的3682例新生儿(其中足月儿1794例,早产儿1888例)为观察对象,采集干血斑行MS/MS遗传代谢病筛查。初次筛查阳性者重新采样复查并行尿液GC-MS检测。根据患儿代谢谱结合临床表现进行生化诊断。统计学方法采用χ^(2)检验。结果3682例NICU患儿中初筛阳性率为5.65%(208/3682),复筛阳性率为1.33%(49/3682),共生化诊断IMD患儿14例,总检出率为0.38%(14/3682),其中足月儿检出率高于早产儿[0.67%(12/1794)与0.11%(2/1888),χ^(2)=7.697,P=0.006]。14例IMD中,有机酸代谢异常11例,包括甲基丙二酸血症8例(57.1%)、戊二酸血症2例(14.3%)、3-甲基戊二烯酸尿症1例(7.1%);氨基酸代谢异常3例,包括尿素循环障碍2例(14.3%)、高苯丙氨酸血症1例(7.1%)。MS/MS初筛假阳性率为5.29%(194/3668),阳性预测值为6.73%(14/208)。召回复查后,二次MS/MS复测,假阳性率为0.95%(35/3668),阳性预测值为28.57%(14/49)。在各类MS/MS指标异常中,丙酰肉碱及其比值增高、戊二酰肉碱增高的阳性预测值高于氨基酸类代谢异常。结论NICU人群IMD发病率较高,且存在早产、感染等多种非遗传因素,干扰MS/MS代谢筛查结果。及时进行MS/MS复查及尿GC-MS分析可以提高诊断效率,明确生化诊断。