Multilayered van der Waals(vdW)materials have attracted increasing interest because of the manipulability of their superior optical,electrical,thermal,and mechanical properties.A mass-spring model(MSM)for elastic wave...Multilayered van der Waals(vdW)materials have attracted increasing interest because of the manipulability of their superior optical,electrical,thermal,and mechanical properties.A mass-spring model(MSM)for elastic wave propagation in multilayered vdW metamaterials is reported in this paper.Molecular dynamics(MD)simulations are adopted to simulate the propagation of elastic waves in multilayered vdW metamaterials.The results show that the graphene/MoS_(2)metamaterials have an elastic wave bandgap in the terahertz range.The MSM for the multilayered vdW metamaterials is proposed,and the numerical simulation results show that this model can well describe the dispersion and transmission characteristics of the multilayered vdW metamaterials.The MSM can predict elastic wave transmission characteristics in multilayered vdW metamaterials stacked with different two-dimensional(2D)materials.The results presented in this paper offer theoretical help for the vibration reduction of multilayered vdW semiconductors.展开更多
The objective of this research is to study the dynamic response characteristics of a three-beam system with intermediate elastic connections under a moving load/mass-spring.In this study,the finite Sine-Fourier transf...The objective of this research is to study the dynamic response characteristics of a three-beam system with intermediate elastic connections under a moving load/mass-spring.In this study,the finite Sine-Fourier transform was performed for the dynamic partial differential equations of a simply supported three-beam system(SSTBS)under a moving load and a moving mass-spring,respectively.The dynamic partial differential equations were transformed into dynamic ordinary differential equations relative to the time coordinates,and the equations were solved and the displacement Fourier amplitude spectral expressions were obtained.Finally,based on finite Sine-Fourier inverse transform,the expressions for dynamic response of SSTBS under the moving load and moving mass-spring were obtained.The proposed method,along with ANSYS,was used to calculate the dynamic response of the SSTBS under a moving load/mass-spring at different speeds.The results obtained herein were consistent with the ANSYS numerical calculation results,verifying the accuracy of the proposed method.The influence of the load/mass-spring’s moving speed on the dynamic deflections of SSTBS were analyzed.SSTBS has several critical speeds under a moving load/mass-spring.The vertical acceleration incurred by a change in the vertical speed of SSTBS due to the movement of mass-spring and the centrifugal acceleration produced by the movement of massspring on the vertical curve generated by SSTBS vibration could not be neglected.展开更多
Fish cage systems are influenced by various oceanic conditions, and the movements and deformation of the system by the external forces can affect the safety of the system itself, as well as the species of fish being c...Fish cage systems are influenced by various oceanic conditions, and the movements and deformation of the system by the external forces can affect the safety of the system itself, as well as the species of fish being cultivated. Structural durability of the system against environmental factors has been major concern for the marine aquaculture system. In this research, a mathematical model and a simulation method were presented for analyzing the performance of the large-scale fish cage system influenced by current and waves. The cage system consisted of netting, mooring ropes, floats, sinkers and floating collar. All the elements were modeled by use of the mass-spring model. The structures were divided into finite elements and mass points were placed at the mid-point of each element, and mass points were connected by springs without mass. Each mass point was applied to external and internal forces, and total force was calculated in every integration step. The computation method was applied to the dynamic simulation of the actual fish cage systems rigged with synthetic fiber and copper wire simultaneously influenced by current and waves. Here, we also tried to find a relevant ratio between buoyancy and sinking force of the fish cages. The simulation results provide improved understanding of the behavior of the structure and valuable information concerning optimum ratio of the buoyancy to sinking force according to current speeds.展开更多
The cutting simulation of soft tissue is important in virtual surgery.It includes three major challenges in computation:Soft tissue simulation,collision detection,and handling,as well as soft tissue models.In order to...The cutting simulation of soft tissue is important in virtual surgery.It includes three major challenges in computation:Soft tissue simulation,collision detection,and handling,as well as soft tissue models.In order to address the earlier challenges,we propose a virtual cutting system based on the mass-spring model.In this system,MSM is utilized to simulate the soft tissue model.Residual stress is introduced to the model for simulating the shrinking effect of soft tissue in cutting.Second,a cylinder-based collision detection method is used to supervise the collision between surgical tools and soft tissue.Third,we simulate the cutting operation with a three-stage cutting method with swept volume,B´ezier curve,and an algorithm named shortest distance nodes matching method.In order to verify the system performance,we carry out three validation experiments on the proposed system:Cutting accuracy experiment,collision detection validation,and practical cutting evaluation.Experiments indicate that our system can well perform the shrinking effect of soft tissue in cutting.The system has fast and accurate collision detection.Moreover,the system can reconstruct smooth incisions vividly.展开更多
In the simulation of acupuncture manipulation,it is necessary to accurately capture the information of acupuncture points and particles around them.Therefore,a soft tissue modeling method that can accurately track mod...In the simulation of acupuncture manipulation,it is necessary to accurately capture the information of acupuncture points and particles around them.Therefore,a soft tissue modeling method that can accurately track model particles is needed.In this paper,a soft tissue acupuncture model based on the mass-spring force net is designed.MSM is used as the auxiliary model and the SHF model is combined.SHF is used to establish a three-layer soft tissue model of skin,fat,and muscle,and a layer of the MSM based force network is covered on the surface of soft tissue to realize the complementary advantages and disadvantages of spherical harmonic function and MSM.In addition,a springback algorithm is designed to simulate the springback phenomenon of soft tissue skin during acupuncture.The evaluation results show that the soft tissue acupuncture modeling method based on mass-spring force net can effectively simulate the springback phenomenon of soft tissue surface during acupuncture surgery,and has good comprehensive performance in the application of virtual acupuncture surgery simulation.展开更多
The main objective of this paper is to investigate the influence of inertia of nonlinear springs on the dispersion behavior of discrete monoatomic chains with lumped and distributed masses.The developed model can repr...The main objective of this paper is to investigate the influence of inertia of nonlinear springs on the dispersion behavior of discrete monoatomic chains with lumped and distributed masses.The developed model can represent the wave propagation problem in a non-homogeneous material consisting of heavy inclusions embedded in a matrix.The inclusions are idealized by lumped masses,and the matrix between adjacent inclusions is modeled by a nonlinear spring with distributed masses.Additionally,the model is capable of depicting the wave propagation in bi-material bars,wherein the first material is represented by a rigid particle and the second one is represented by a nonlinear spring with distributed masses.The discrete model of the nonlinear monoatomic chain with lumped and distributed masses is first considered,and a closed-form expression of the dispersion relation is obtained by the second-order Lindstedt-Poincare method(LPM).Next,a continuum model for the nonlinear monoatomic chain is derived directly from its discrete lattice model by a suitable continualization technique.The subsequent use of the second-order method of multiple scales(MMS)facilitates the derivation of the corresponding nonlinear dispersion relation in a closed form.The novelties of the present study consist of(i)considering the inertia of nonlinear springs on the dispersion behavior of the discrete mass-spring chains;(ii)developing the second-order LPM for the wave propagation in the discrete chains;and(iii)deriving a continuum model for the nonlinear monoatomic chains with lumped and distributed masses.Finally,a parametric study is conducted to examine the effects of the design parameters and the distributed spring mass on the nonlinear dispersion relations and phase velocities obtained from both the discrete and continuum models.These parameters include the ratio of the spring mass to the lumped mass,the nonlinear stiffness coefficient of the spring,and the wave amplitude.展开更多
AIM:To investigate the efficiency of Cox proportional hazard model in detecting prognostic factors for gastric cancer.METHODS:We used the log-normal regression model to evaluate prognostic factors in gastric cancer an...AIM:To investigate the efficiency of Cox proportional hazard model in detecting prognostic factors for gastric cancer.METHODS:We used the log-normal regression model to evaluate prognostic factors in gastric cancer and compared it with the Cox model.Three thousand and eighteen gastric cancer patients who received a gastrectomy between 1980 and 2004 were retrospectively evaluated.Clinic-pathological factors were included in a log-normal model as well as Cox model.The akaike information criterion (AIC) was employed to compare the efficiency of both models.Univariate analysis indicated that age at diagnosis,past history,cancer location,distant metastasis status,surgical curative degree,combined other organ resection,Borrmann type,Lauren's classification,pT stage,total dissected nodes and pN stage were prognostic factors in both log-normal and Cox models.RESULTS:In the final multivariate model,age at diagnosis,past history,surgical curative degree,Borrmann type,Lauren's classification,pT stage,and pN stage were significant prognostic factors in both log-normal and Cox models.However,cancer location,distant metastasis status,and histology types were found to be significant prognostic factors in log-normal results alone.According to AIC,the log-normal model performed better than the Cox proportional hazard model (AIC value:2534.72 vs 1693.56).CONCLUSION:It is suggested that the log-normal regression model can be a useful statistical model to evaluate prognostic factors instead of the Cox proportional hazard model.展开更多
Advanced driver assistance systems(ADAS) seek to provide drivers and passengers of automotive vehicles increased safety and comfort. Original equipment manufacturers are integrating and developing systems for distance...Advanced driver assistance systems(ADAS) seek to provide drivers and passengers of automotive vehicles increased safety and comfort. Original equipment manufacturers are integrating and developing systems for distance keeping, lane keeping and changing and other functionalities. The modern automobile is a complex system of systems. How the functionalities of advanced driver assistance are implemented and coordinated across the systems of the vehicle is generally not made available to the wider research community by the developers and manufactures. This paper seeks to begin filling this gap by assembling open source physics models of the vehicle dynamics and ADAS command models. Additionally, in order to facilitate ADAS development and testing without having access to the details of ADAS, a coordinated control architecture for motion management is also proposed for distributing ADAS motion control commands over vehicle systems. The architecture is demonstrated in a case study where motion is coordinated between the steering and the braking systems, which are typically used only for a single functionality. The integrated vehicle and system dynamics using the coordinated control architecture are simulated for various driving tasks. It is seen that improved trajectory following can be achieved by the proposed coordinated control architecture. The models, simulations and control architecture are made available for open access.展开更多
We investigate the interaction between a positive mass and a negative effective mass through a three- mass chain connected with elastic springs, a pair of masses is designed to have an effective negative mass, and it ...We investigate the interaction between a positive mass and a negative effective mass through a three- mass chain connected with elastic springs, a pair of masses is designed to have an effective negative mass, and it interacts with the third positive one as if an equivalent two-mass chain. The dynamics of the equivalent two-mass chain shows that the two bodies may be self-accelerated in same direction when the effective mass becomes negative, the experiment is also conducted to demonstrate this type of motion. We further show that the energy principle (Hamilton's principle) is applicable if the energy of the negative mass unit is properly characterized. The result may be relevant to composite with cells of effective negative mass, their interaction with matrix may lead to more richer unexpected macroscopic responses.展开更多
The Covid-19 epidemic is an emerging infectious disease of the viral zoonosis type caused by the coronavirus strain SARS-CoV-2, it is classified as a human-to-human communicable disease and is currently a pandemic wor...The Covid-19 epidemic is an emerging infectious disease of the viral zoonosis type caused by the coronavirus strain SARS-CoV-2, it is classified as a human-to-human communicable disease and is currently a pandemic worldwide. In this paper, we propose conceptual mathematical models of the epidemic dynamics of four compartments. We have collected data from the Djibouti health ministry. We study the positivity, boundedness, existence and uniqueness of the weak solution. Next, we define the Basic reproduction number by the method of the DFE and EEP. Then, we study the local and global stability and the bifurcation analysis of equilibrium to examine its epidemiological relevance. Finally, we analyze the fit of the data in comparison with the result of our mathematical results, to validate the model and estimate the important model parameters and prediction about the disease. We consider the real cases of Djibouti from 15th March to 15th May 2021.展开更多
A partide system model is presented for the simulation of fabric draping. The interaction of each partide is based on a refined mass-spring structure. Regarded the fabric material as an orthotropic continuum, the refi...A partide system model is presented for the simulation of fabric draping. The interaction of each partide is based on a refined mass-spring structure. Regarded the fabric material as an orthotropic continuum, the refinement of our model is focused on the construction of mechanical responses of bending and shearing springs by means of a piecewise polynomial approximation of KES-F testing data. In this way, the draping figure of a silk fabric, a wool fabric and a polyester fabric are simulated. The static final shape and animation of simulation proves that our model has developed an efficient technique on real fabric- drape modeling, and the little computation time of the simulation execution on a PC with Celeron 450 CPU may meet the requirement of real-time simulation.展开更多
The purpose of this research is to define initial parameters of Khyargas Lake-Zavkhan River and its catchment area using satellite images. The study has been done by two datasets: 1) Shuttle Radar Topography Mission (...The purpose of this research is to define initial parameters of Khyargas Lake-Zavkhan River and its catchment area using satellite images. The study has been done by two datasets: 1) Shuttle Radar Topography Mission (SRTM) at a horizontal spatial resolution of 90 meters, 2) The Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) at a horizontal spatial resolution of 30 meters, using two different models of ArcHydro and Integrated Land and Water Information System (ILWIS) softwares. Main methods of models, that were used in this research are the Deterministic-8, the steepest slope, the spread, the seek computations and the trace analysis. Moreover, input data of the modeling are digital elevation model (DEM) and lake position, outlet location of the river. DEM based ArcHydro model was run on the both datasets, and ILWIS model was run on SRTM data. Several intermediate results were produced while the models run, and initial parameters of the Zavkhan River, its catchment area have been defined at the end of the model. Moreover, final results of the models were compared with each other and with the result of previous research, and with the reality. The result of this study can be used in baseline and advanced research on the catchment area. Besides of that, the result can define a spatial boundary of study on Zavkhan River and its catchment area. Moreover, it would have support for decision-making on ground and surface water resource, distribution and management. Further research, which will cover the entire territory of Mongolia, has to be done using same methodology. The 332nd decision on “River catchment areas of Mongolia” of the Minister of Nature, Environment and Tourism in 2009 has to renew, if a result of that study would be accepted from vocational organization and experts.展开更多
This paper presents a parallel method for simulating real-time 3D deformable objects using the volume preservation mass-spring system method on tetrahedron meshes.In general,the conventional mass-spring system is mani...This paper presents a parallel method for simulating real-time 3D deformable objects using the volume preservation mass-spring system method on tetrahedron meshes.In general,the conventional mass-spring system is manipulated as a force-driven method because it is fast,simple to implement,and the parameters can be controlled.However,the springs in traditional mass-spring system can be excessively elongated which cause severe stability and robustness issues that lead to shape restoring,simulation blow-up,and huge volume loss of the deformable object.In addition,traditional method that uses a serial process of the central processing unit(CPU)to solve the system in every frame cannot handle the complex structure of deformable object in real-time.Therefore,the first order implicit constraint enforcement for a mass-spring model is utilized to achieve accurate visual realism of deformable objects with tough constraint error.In this paper,we applied the distance constraint and volume conservation constraints for each tetrahedron element to improve the stability of deformable object simulation using the mass-spring system and behave the same as its real-world counterparts.To reduce the computational complexity while ensuring stable simulation,we applied a method that utilizes OpenGL compute shader,a part of OpenGL Shading Language(GLSL)that executes on the graphic processing unit(GPU)to solve the numerical problems effectively.We applied the proposed methods to experimental volumetric models,and volume percentages of all objects are compared.The average volume percentages of all models during the simulation using the mass-spring system,distance constraint,and the volume constraint method were 68.21%,89.64%,and 98.70%,respectively.The proposed approaches are successfully applied to improve the stability of mass-spring system and the performance comparison from our experimental tests also shows that the GPU-based method is faster than CPU-based implementation for all cases.展开更多
The sophisticated structures of flapping insect wings make it challenging to study the role of wing flexibility in insect flight.In this study,a mass-spring system is used to model wing structural dynamics as a thin,f...The sophisticated structures of flapping insect wings make it challenging to study the role of wing flexibility in insect flight.In this study,a mass-spring system is used to model wing structural dynamics as a thin,flexible membrane supported by a network of veins.The vein mechanical properties can be estimated based on their diameters and the Young's modulus of cuticle.In order to analyze the effect of wing flexibility,the Young's modulus is varied to make a comparison between two different wing models that we refer to as flexible and highly flexible.The wing models are coupled with a pseudo-spectral code solving the incompressible Navier–Stokes equations,allowing us to investigate the influence of wing deformation on the aerodynamic efficiency of a tethered flapping bumblebee.Compared to the bumblebee model with rigid wings,the one with flexible wings flies more efficiently,characterized by a larger lift-to-power ratio.展开更多
A real-time animation technique for a kind of non-rigid objects, flexible and thin objects, is proposed, which can update with stability the state of n mass points of the mass-spring (MS) modei with time complexity of...A real-time animation technique for a kind of non-rigid objects, flexible and thin objects, is proposed, which can update with stability the state of n mass points of the mass-spring (MS) modei with time complexity of O (n ). The new implicit numerical integration technique of the authors, which is based on a simple approximation of the linear system, has great advantages over the existing implicit integration methods. Moreover, experiment shows that the new technique is highly efficient in animating a kind of non-rigid objects, and suitable for the draping module of the 3D garment CAD system.展开更多
Sleep spindle is the characteristic waveform of electroencephalogram (EEG) which is important for clinical diagnosis. In this study, an automatic sleep spindle detection method was developed. The EEG signals were reco...Sleep spindle is the characteristic waveform of electroencephalogram (EEG) which is important for clinical diagnosis. In this study, an automatic sleep spindle detection method was developed. The EEG signals were recorded based on the standard polysomnogram (PSG) measurement. A preprocessing procedure is introduced to exclude the unnecessary data segments and normalized the necessary data segments. Complex demodulation method is adopted to detect the candidate sleep spindle waveforms and calculate the features. The sleep spindles are recognized based on a decision tree model. Finally, the detected sleep spindles were utilized to amend the sleep stage recognition results. The sleep EEG data from 3 patients with sleep disorders were analyzed. The obtained results showed that the detected sleep spindles in EEG signal improved the accuracy of sleep stage recognition.展开更多
Objectives: Monocytes/macrophages accumulate in the synovial membrane in rheumatoid arthritis and play a key role in disease pathogenesis, contributing to inflammation, cartilage destruction and bone erosion. Identifi...Objectives: Monocytes/macrophages accumulate in the synovial membrane in rheumatoid arthritis and play a key role in disease pathogenesis, contributing to inflammation, cartilage destruction and bone erosion. Identification of molecules involved in monocyte/macrophage recruitment in inflammation is crucial for development of therapeutic interventions. Chemokine receptor CCR9 is up-regulated on these cells in peripheral blood and synovium of rheumatoid patients. This study investigated the course of antigen-induced arthritis in CCR9 deficient C57BL/6 mice in comparison to wild type animals to determine whether CCR9 is critical for disease severity and progression. Methods: Methylated bovine serum albumin was used for induction of uni-lateral arthritis by direct injection into the knee joints of preimmunized animals. Arthritis is confined to the injected joint allowing comparison with the normal opposing joint. Clinical severity of arthritis was assessed by measuring swelling in the arthritic joint in comparison to the normal joint. Histological analysis was performed to assess the extent of leukocyte infiltration and cartilage depletion. Results: Levels of swelling were not significantly different between wild type and CCR9 deficient mice. Similarly there was no significant difference in histological severity of arthritis when comparing CCR9-deficient mice to wild type mice. Conclusions: CCR9 was not required for development of synovial inflammation and cartilage destruction in the anti-gen-induced model of arthritis in C57BL/6 mice in this study. This may reflect a true lack of a pathogenic role of CCR9 on monocyte/macrophage function in vivo or it may reflect differences in the current antigen-induced arthritis model when compared to human RA.展开更多
The state of the physics of convective clouds and cloud seeding is discussed briefly. It is noted that at the present time there is a transition from the stage of investigation of “elementary” processes in the cloud...The state of the physics of convective clouds and cloud seeding is discussed briefly. It is noted that at the present time there is a transition from the stage of investigation of “elementary” processes in the clouds to the stage of studying the formation of macro- and microstructural characteristics of clouds as a whole, taking into account their system properties. The main directions of the development of cloud physics at the upcoming stage of its development are discussed. The paper points out that one of these areas is the determination of the structure-forming factors for the clouds and the study of their influence on their formation and evolution. It is noted that one of such factors is the interaction of clouds with their surrounding atmosphere, and the main method of studying its role in the processes of cloud formation is mathematical modeling. A three-dimensional nonstationary model of convective clouds is presented with a detailed account of the processes of thermohydrodynamics and microphysics, which is used for research. The results of modeling the influence of the wind field structure in the atmosphere on the formation and evolution of clouds are presented. It is shown that the dynamic characteristics of the atmosphere have a significant effect on the formation of macro- and microstructural characteristics of convective clouds: the more complex the structure of the wind field in the atmosphere (i.e., the more intense the interaction of the atmosphere and the cloud), the less powerful the clouds are formed.展开更多
基金supported by the National Science Fund for Distinguished Young Scholars of China(No.11925205)the National Natural Science Foundation of China(Nos.51921003 and U2341230)。
文摘Multilayered van der Waals(vdW)materials have attracted increasing interest because of the manipulability of their superior optical,electrical,thermal,and mechanical properties.A mass-spring model(MSM)for elastic wave propagation in multilayered vdW metamaterials is reported in this paper.Molecular dynamics(MD)simulations are adopted to simulate the propagation of elastic waves in multilayered vdW metamaterials.The results show that the graphene/MoS_(2)metamaterials have an elastic wave bandgap in the terahertz range.The MSM for the multilayered vdW metamaterials is proposed,and the numerical simulation results show that this model can well describe the dispersion and transmission characteristics of the multilayered vdW metamaterials.The MSM can predict elastic wave transmission characteristics in multilayered vdW metamaterials stacked with different two-dimensional(2D)materials.The results presented in this paper offer theoretical help for the vibration reduction of multilayered vdW semiconductors.
基金The Fundamental Research Funds for the Central Universities of Central South University under Grant No.2018zzts189the National Natural Science Foundations of China under Grant Nos.51408449 and 51778630the Innovation-driven Plan in Central South University under Grant No.2015CX006。
文摘The objective of this research is to study the dynamic response characteristics of a three-beam system with intermediate elastic connections under a moving load/mass-spring.In this study,the finite Sine-Fourier transform was performed for the dynamic partial differential equations of a simply supported three-beam system(SSTBS)under a moving load and a moving mass-spring,respectively.The dynamic partial differential equations were transformed into dynamic ordinary differential equations relative to the time coordinates,and the equations were solved and the displacement Fourier amplitude spectral expressions were obtained.Finally,based on finite Sine-Fourier inverse transform,the expressions for dynamic response of SSTBS under the moving load and moving mass-spring were obtained.The proposed method,along with ANSYS,was used to calculate the dynamic response of the SSTBS under a moving load/mass-spring at different speeds.The results obtained herein were consistent with the ANSYS numerical calculation results,verifying the accuracy of the proposed method.The influence of the load/mass-spring’s moving speed on the dynamic deflections of SSTBS were analyzed.SSTBS has several critical speeds under a moving load/mass-spring.The vertical acceleration incurred by a change in the vertical speed of SSTBS due to the movement of mass-spring and the centrifugal acceleration produced by the movement of massspring on the vertical curve generated by SSTBS vibration could not be neglected.
基金supported by the National Research Foundation of Korea Grant founded by the Korean Government(MEST)(Grant No.NRF-2013R1A1A4A01011445)
文摘Fish cage systems are influenced by various oceanic conditions, and the movements and deformation of the system by the external forces can affect the safety of the system itself, as well as the species of fish being cultivated. Structural durability of the system against environmental factors has been major concern for the marine aquaculture system. In this research, a mathematical model and a simulation method were presented for analyzing the performance of the large-scale fish cage system influenced by current and waves. The cage system consisted of netting, mooring ropes, floats, sinkers and floating collar. All the elements were modeled by use of the mass-spring model. The structures were divided into finite elements and mass points were placed at the mid-point of each element, and mass points were connected by springs without mass. Each mass point was applied to external and internal forces, and total force was calculated in every integration step. The computation method was applied to the dynamic simulation of the actual fish cage systems rigged with synthetic fiber and copper wire simultaneously influenced by current and waves. Here, we also tried to find a relevant ratio between buoyancy and sinking force of the fish cages. The simulation results provide improved understanding of the behavior of the structure and valuable information concerning optimum ratio of the buoyancy to sinking force according to current speeds.
基金This work was supported,in part,by the National Nature Science Foundation of China under Grant Nos.61502240,61502096,61304205,61773219in part,by the Natural Science Foundation of Jiangsu Province under Grant Nos.BK20191401 and BK20201136+2 种基金in part,by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)fundin part,by the Collaborative Innovation Center of Atmospheric Environment and Equipment Technology(CICAEET)fundNUIST Students’Platform for Innovation and Entrepreneurship Training Program.
文摘The cutting simulation of soft tissue is important in virtual surgery.It includes three major challenges in computation:Soft tissue simulation,collision detection,and handling,as well as soft tissue models.In order to address the earlier challenges,we propose a virtual cutting system based on the mass-spring model.In this system,MSM is utilized to simulate the soft tissue model.Residual stress is introduced to the model for simulating the shrinking effect of soft tissue in cutting.Second,a cylinder-based collision detection method is used to supervise the collision between surgical tools and soft tissue.Third,we simulate the cutting operation with a three-stage cutting method with swept volume,B´ezier curve,and an algorithm named shortest distance nodes matching method.In order to verify the system performance,we carry out three validation experiments on the proposed system:Cutting accuracy experiment,collision detection validation,and practical cutting evaluation.Experiments indicate that our system can well perform the shrinking effect of soft tissue in cutting.The system has fast and accurate collision detection.Moreover,the system can reconstruct smooth incisions vividly.
基金This work was supported,in part,by the National Nature Science Foundation of China under Grant Numbers 61773219in part,by the Natural Science Foundation of Jiangsu Province under Grant Number BK20201136,BK20191401+2 种基金in part,by the Priority Academic Program Development of Jiangsu Higher Education Institutions(PAPD)fundin part,by the Collaborative Innovation Center of Atmospheric Environment and Equipment Technology(CICAEET)fundNUIST Students’Platform for Innovation and Entrepreneurship Training Program.
文摘In the simulation of acupuncture manipulation,it is necessary to accurately capture the information of acupuncture points and particles around them.Therefore,a soft tissue modeling method that can accurately track model particles is needed.In this paper,a soft tissue acupuncture model based on the mass-spring force net is designed.MSM is used as the auxiliary model and the SHF model is combined.SHF is used to establish a three-layer soft tissue model of skin,fat,and muscle,and a layer of the MSM based force network is covered on the surface of soft tissue to realize the complementary advantages and disadvantages of spherical harmonic function and MSM.In addition,a springback algorithm is designed to simulate the springback phenomenon of soft tissue skin during acupuncture.The evaluation results show that the soft tissue acupuncture modeling method based on mass-spring force net can effectively simulate the springback phenomenon of soft tissue surface during acupuncture surgery,and has good comprehensive performance in the application of virtual acupuncture surgery simulation.
基金the support of Texas A&M University at Qatar for the 2022 Sixth Cycle Seed Grant Project。
文摘The main objective of this paper is to investigate the influence of inertia of nonlinear springs on the dispersion behavior of discrete monoatomic chains with lumped and distributed masses.The developed model can represent the wave propagation problem in a non-homogeneous material consisting of heavy inclusions embedded in a matrix.The inclusions are idealized by lumped masses,and the matrix between adjacent inclusions is modeled by a nonlinear spring with distributed masses.Additionally,the model is capable of depicting the wave propagation in bi-material bars,wherein the first material is represented by a rigid particle and the second one is represented by a nonlinear spring with distributed masses.The discrete model of the nonlinear monoatomic chain with lumped and distributed masses is first considered,and a closed-form expression of the dispersion relation is obtained by the second-order Lindstedt-Poincare method(LPM).Next,a continuum model for the nonlinear monoatomic chain is derived directly from its discrete lattice model by a suitable continualization technique.The subsequent use of the second-order method of multiple scales(MMS)facilitates the derivation of the corresponding nonlinear dispersion relation in a closed form.The novelties of the present study consist of(i)considering the inertia of nonlinear springs on the dispersion behavior of the discrete mass-spring chains;(ii)developing the second-order LPM for the wave propagation in the discrete chains;and(iii)deriving a continuum model for the nonlinear monoatomic chains with lumped and distributed masses.Finally,a parametric study is conducted to examine the effects of the design parameters and the distributed spring mass on the nonlinear dispersion relations and phase velocities obtained from both the discrete and continuum models.These parameters include the ratio of the spring mass to the lumped mass,the nonlinear stiffness coefficient of the spring,and the wave amplitude.
基金Supported by the Gastric Cancer Laboratory and Pathology Department of Chinese Medical University,Shenyang,Chinathe Science and Technology Program of Shenyang,No. 1081232-1-00
文摘AIM:To investigate the efficiency of Cox proportional hazard model in detecting prognostic factors for gastric cancer.METHODS:We used the log-normal regression model to evaluate prognostic factors in gastric cancer and compared it with the Cox model.Three thousand and eighteen gastric cancer patients who received a gastrectomy between 1980 and 2004 were retrospectively evaluated.Clinic-pathological factors were included in a log-normal model as well as Cox model.The akaike information criterion (AIC) was employed to compare the efficiency of both models.Univariate analysis indicated that age at diagnosis,past history,cancer location,distant metastasis status,surgical curative degree,combined other organ resection,Borrmann type,Lauren's classification,pT stage,total dissected nodes and pN stage were prognostic factors in both log-normal and Cox models.RESULTS:In the final multivariate model,age at diagnosis,past history,surgical curative degree,Borrmann type,Lauren's classification,pT stage,and pN stage were significant prognostic factors in both log-normal and Cox models.However,cancer location,distant metastasis status,and histology types were found to be significant prognostic factors in log-normal results alone.According to AIC,the log-normal model performed better than the Cox proportional hazard model (AIC value:2534.72 vs 1693.56).CONCLUSION:It is suggested that the log-normal regression model can be a useful statistical model to evaluate prognostic factors instead of the Cox proportional hazard model.
基金supported by the Programme for Simulation Innovation(PSI)
文摘Advanced driver assistance systems(ADAS) seek to provide drivers and passengers of automotive vehicles increased safety and comfort. Original equipment manufacturers are integrating and developing systems for distance keeping, lane keeping and changing and other functionalities. The modern automobile is a complex system of systems. How the functionalities of advanced driver assistance are implemented and coordinated across the systems of the vehicle is generally not made available to the wider research community by the developers and manufactures. This paper seeks to begin filling this gap by assembling open source physics models of the vehicle dynamics and ADAS command models. Additionally, in order to facilitate ADAS development and testing without having access to the details of ADAS, a coordinated control architecture for motion management is also proposed for distributing ADAS motion control commands over vehicle systems. The architecture is demonstrated in a case study where motion is coordinated between the steering and the braking systems, which are typically used only for a single functionality. The integrated vehicle and system dynamics using the coordinated control architecture are simulated for various driving tasks. It is seen that improved trajectory following can be achieved by the proposed coordinated control architecture. The models, simulations and control architecture are made available for open access.
基金supported by the National Natural Science Foundation of China (Grant Nos.11290153 and 11221202)
文摘We investigate the interaction between a positive mass and a negative effective mass through a three- mass chain connected with elastic springs, a pair of masses is designed to have an effective negative mass, and it interacts with the third positive one as if an equivalent two-mass chain. The dynamics of the equivalent two-mass chain shows that the two bodies may be self-accelerated in same direction when the effective mass becomes negative, the experiment is also conducted to demonstrate this type of motion. We further show that the energy principle (Hamilton's principle) is applicable if the energy of the negative mass unit is properly characterized. The result may be relevant to composite with cells of effective negative mass, their interaction with matrix may lead to more richer unexpected macroscopic responses.
文摘The Covid-19 epidemic is an emerging infectious disease of the viral zoonosis type caused by the coronavirus strain SARS-CoV-2, it is classified as a human-to-human communicable disease and is currently a pandemic worldwide. In this paper, we propose conceptual mathematical models of the epidemic dynamics of four compartments. We have collected data from the Djibouti health ministry. We study the positivity, boundedness, existence and uniqueness of the weak solution. Next, we define the Basic reproduction number by the method of the DFE and EEP. Then, we study the local and global stability and the bifurcation analysis of equilibrium to examine its epidemiological relevance. Finally, we analyze the fit of the data in comparison with the result of our mathematical results, to validate the model and estimate the important model parameters and prediction about the disease. We consider the real cases of Djibouti from 15th March to 15th May 2021.
文摘A partide system model is presented for the simulation of fabric draping. The interaction of each partide is based on a refined mass-spring structure. Regarded the fabric material as an orthotropic continuum, the refinement of our model is focused on the construction of mechanical responses of bending and shearing springs by means of a piecewise polynomial approximation of KES-F testing data. In this way, the draping figure of a silk fabric, a wool fabric and a polyester fabric are simulated. The static final shape and animation of simulation proves that our model has developed an efficient technique on real fabric- drape modeling, and the little computation time of the simulation execution on a PC with Celeron 450 CPU may meet the requirement of real-time simulation.
文摘The purpose of this research is to define initial parameters of Khyargas Lake-Zavkhan River and its catchment area using satellite images. The study has been done by two datasets: 1) Shuttle Radar Topography Mission (SRTM) at a horizontal spatial resolution of 90 meters, 2) The Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER) at a horizontal spatial resolution of 30 meters, using two different models of ArcHydro and Integrated Land and Water Information System (ILWIS) softwares. Main methods of models, that were used in this research are the Deterministic-8, the steepest slope, the spread, the seek computations and the trace analysis. Moreover, input data of the modeling are digital elevation model (DEM) and lake position, outlet location of the river. DEM based ArcHydro model was run on the both datasets, and ILWIS model was run on SRTM data. Several intermediate results were produced while the models run, and initial parameters of the Zavkhan River, its catchment area have been defined at the end of the model. Moreover, final results of the models were compared with each other and with the result of previous research, and with the reality. The result of this study can be used in baseline and advanced research on the catchment area. Besides of that, the result can define a spatial boundary of study on Zavkhan River and its catchment area. Moreover, it would have support for decision-making on ground and surface water resource, distribution and management. Further research, which will cover the entire territory of Mongolia, has to be done using same methodology. The 332nd decision on “River catchment areas of Mongolia” of the Minister of Nature, Environment and Tourism in 2009 has to renew, if a result of that study would be accepted from vocational organization and experts.
基金This work was supported by the Basic Science Research Program through the National Research Foundation of Korea(NRF-2019R1F1A1062752)funded by the Ministry of Education+1 种基金was funded by BK21 FOUR(Fostering Outstanding Universities for Research)(No.:5199990914048)and was also supported by the Soonchunhyang University Research Fund.
文摘This paper presents a parallel method for simulating real-time 3D deformable objects using the volume preservation mass-spring system method on tetrahedron meshes.In general,the conventional mass-spring system is manipulated as a force-driven method because it is fast,simple to implement,and the parameters can be controlled.However,the springs in traditional mass-spring system can be excessively elongated which cause severe stability and robustness issues that lead to shape restoring,simulation blow-up,and huge volume loss of the deformable object.In addition,traditional method that uses a serial process of the central processing unit(CPU)to solve the system in every frame cannot handle the complex structure of deformable object in real-time.Therefore,the first order implicit constraint enforcement for a mass-spring model is utilized to achieve accurate visual realism of deformable objects with tough constraint error.In this paper,we applied the distance constraint and volume conservation constraints for each tetrahedron element to improve the stability of deformable object simulation using the mass-spring system and behave the same as its real-world counterparts.To reduce the computational complexity while ensuring stable simulation,we applied a method that utilizes OpenGL compute shader,a part of OpenGL Shading Language(GLSL)that executes on the graphic processing unit(GPU)to solve the numerical problems effectively.We applied the proposed methods to experimental volumetric models,and volume percentages of all objects are compared.The average volume percentages of all models during the simulation using the mass-spring system,distance constraint,and the volume constraint method were 68.21%,89.64%,and 98.70%,respectively.The proposed approaches are successfully applied to improve the stability of mass-spring system and the performance comparison from our experimental tests also shows that the GPU-based method is faster than CPU-based implementation for all cases.
基金Financial support from the Agence Nationale de la Recherche(ANR)(Grant 15-CE40-0019)and Deutsche Forschungsgemeinschaft(DFG)(Grant SE 824/26-1),project AIFITHPC resources of IDRIS under the allocation No.2018-91664 attributed by Grand Equipement National de Calcul Intensif(GENCI)+2 种基金Centre de Calcul Intensif d'Aix-Marseille is acknowledged for granting access to its high performance computing resources financed by the project Equip@Meso(No.ANR-10-EQPX-29-01)financial support granted by the ministeres des Affaires etrangeres et du developpement international(MAEDI)et de l'Education nationale et l'enseignement superieur,de la recherche et de l'innovation(MENESRI),the Deutscher Akademischer Austauschdienst(DAAD)within the French-German Procope project FIFITfinancial support from the JSPS KAKENHI Grant No.JP18K13693。
文摘The sophisticated structures of flapping insect wings make it challenging to study the role of wing flexibility in insect flight.In this study,a mass-spring system is used to model wing structural dynamics as a thin,flexible membrane supported by a network of veins.The vein mechanical properties can be estimated based on their diameters and the Young's modulus of cuticle.In order to analyze the effect of wing flexibility,the Young's modulus is varied to make a comparison between two different wing models that we refer to as flexible and highly flexible.The wing models are coupled with a pseudo-spectral code solving the incompressible Navier–Stokes equations,allowing us to investigate the influence of wing deformation on the aerodynamic efficiency of a tethered flapping bumblebee.Compared to the bumblebee model with rigid wings,the one with flexible wings flies more efficiently,characterized by a larger lift-to-power ratio.
文摘A real-time animation technique for a kind of non-rigid objects, flexible and thin objects, is proposed, which can update with stability the state of n mass points of the mass-spring (MS) modei with time complexity of O (n ). The new implicit numerical integration technique of the authors, which is based on a simple approximation of the linear system, has great advantages over the existing implicit integration methods. Moreover, experiment shows that the new technique is highly efficient in animating a kind of non-rigid objects, and suitable for the draping module of the 3D garment CAD system.
文摘Sleep spindle is the characteristic waveform of electroencephalogram (EEG) which is important for clinical diagnosis. In this study, an automatic sleep spindle detection method was developed. The EEG signals were recorded based on the standard polysomnogram (PSG) measurement. A preprocessing procedure is introduced to exclude the unnecessary data segments and normalized the necessary data segments. Complex demodulation method is adopted to detect the candidate sleep spindle waveforms and calculate the features. The sleep spindles are recognized based on a decision tree model. Finally, the detected sleep spindles were utilized to amend the sleep stage recognition results. The sleep EEG data from 3 patients with sleep disorders were analyzed. The obtained results showed that the detected sleep spindles in EEG signal improved the accuracy of sleep stage recognition.
文摘Objectives: Monocytes/macrophages accumulate in the synovial membrane in rheumatoid arthritis and play a key role in disease pathogenesis, contributing to inflammation, cartilage destruction and bone erosion. Identification of molecules involved in monocyte/macrophage recruitment in inflammation is crucial for development of therapeutic interventions. Chemokine receptor CCR9 is up-regulated on these cells in peripheral blood and synovium of rheumatoid patients. This study investigated the course of antigen-induced arthritis in CCR9 deficient C57BL/6 mice in comparison to wild type animals to determine whether CCR9 is critical for disease severity and progression. Methods: Methylated bovine serum albumin was used for induction of uni-lateral arthritis by direct injection into the knee joints of preimmunized animals. Arthritis is confined to the injected joint allowing comparison with the normal opposing joint. Clinical severity of arthritis was assessed by measuring swelling in the arthritic joint in comparison to the normal joint. Histological analysis was performed to assess the extent of leukocyte infiltration and cartilage depletion. Results: Levels of swelling were not significantly different between wild type and CCR9 deficient mice. Similarly there was no significant difference in histological severity of arthritis when comparing CCR9-deficient mice to wild type mice. Conclusions: CCR9 was not required for development of synovial inflammation and cartilage destruction in the anti-gen-induced model of arthritis in C57BL/6 mice in this study. This may reflect a true lack of a pathogenic role of CCR9 on monocyte/macrophage function in vivo or it may reflect differences in the current antigen-induced arthritis model when compared to human RA.
文摘The state of the physics of convective clouds and cloud seeding is discussed briefly. It is noted that at the present time there is a transition from the stage of investigation of “elementary” processes in the clouds to the stage of studying the formation of macro- and microstructural characteristics of clouds as a whole, taking into account their system properties. The main directions of the development of cloud physics at the upcoming stage of its development are discussed. The paper points out that one of these areas is the determination of the structure-forming factors for the clouds and the study of their influence on their formation and evolution. It is noted that one of such factors is the interaction of clouds with their surrounding atmosphere, and the main method of studying its role in the processes of cloud formation is mathematical modeling. A three-dimensional nonstationary model of convective clouds is presented with a detailed account of the processes of thermohydrodynamics and microphysics, which is used for research. The results of modeling the influence of the wind field structure in the atmosphere on the formation and evolution of clouds are presented. It is shown that the dynamic characteristics of the atmosphere have a significant effect on the formation of macro- and microstructural characteristics of convective clouds: the more complex the structure of the wind field in the atmosphere (i.e., the more intense the interaction of the atmosphere and the cloud), the less powerful the clouds are formed.