Purpose: This was a preliminary study to assess surgical construction and regeneration of mastoid air cells in the treatment of cholesteatoma. Methods: Two-stage tympanoplasty with mastoidectomy was performed in four ...Purpose: This was a preliminary study to assess surgical construction and regeneration of mastoid air cells in the treatment of cholesteatoma. Methods: Two-stage tympanoplasty with mastoidectomy was performed in four cases of unilateral cholesteatoma with sclerotic mastoid. During the first-stage operation, small fragments of autologous cortical bone were inserted into the cavity after mastoidectomy to form a honeycomb-like structure. Reconstruction of the lateral wall of the mastoid cavity was performed using the mastoid cortical bony plate. Pre- and postoperative mastoid volume was evaluated by three-dimensional reconstruction based on high-resolution computed tomography (HR-CT) images. Results: HR-CT images after the first-stage operation showed that mastoid volume had increased in all subjects. Macroscopic inspection during the second-stage operation revealed that the honeycomb-like structure made of bony fragments and covered by thin mucosa in the mastoid cavity was stable, with no evidence of effusion or granulation tissue. No retraction of the eardrum, middle ear effusion or recurrence of cholesteatoma was observed, and the hearing level on a pure-tone audiogram was improved in any subject 60 - 94 months after the second-stage operation. Conclusion: Surgical construction and regeneration of mastoid air cells using autologous cortical bone can be useful in treatment of cholesteatoma with arrested mastoid pneumatization.展开更多
目的 观察自体乳突皮质骨粉行乳突填塞重建外耳道后壁的临床疗效。方法 43例慢性化脓性中耳炎或中耳胆脂瘤患者行乳突开放＋鼓室成形术后,应用自体乳突皮质骨粉填塞乳突术腔行外耳道后壁重建术,加耳甲腔成形术。结果 术后随访时间3~22个...目的 观察自体乳突皮质骨粉行乳突填塞重建外耳道后壁的临床疗效。方法 43例慢性化脓性中耳炎或中耳胆脂瘤患者行乳突开放＋鼓室成形术后,应用自体乳突皮质骨粉填塞乳突术腔行外耳道后壁重建术,加耳甲腔成形术。结果 术后随访时间3~22个月,平均13.4个月;所有病例均干耳,术后干耳时间为20-56 d,平均为31.7 d。言语频率（0.5、1、2 k Hz）平均纯音听力（pure tone average,PTA）气导由术前55.0±6.2 d B提高到术后34.0±3.2 d B,骨导由术前28.1±4.4 d B提高到术后21.5±4.1 d B,气骨导差（air-bone gap,ABG）由术前26.8±7.8 d B缩小到12.5±4.1 d B,术后听力提高成功率（术后PTA-ABG≤20 d B）为74.4%（32/43例）。除4例出现填塞骨粉感染、散落外,术后所有患者外耳道形态接近正常解剖结构,鼓膜形态正常,无再穿孔及内陷袋形成,外耳道后壁重建成功率为90.7%（39/43例）。结论 中耳乳突开放术后应用自体乳突皮质骨粉填塞乳突术腔行外耳道后壁重建术,是缩小乳突术腔,获得近似正常的外耳道解剖形态结构的有效方法。展开更多
文摘Purpose: This was a preliminary study to assess surgical construction and regeneration of mastoid air cells in the treatment of cholesteatoma. Methods: Two-stage tympanoplasty with mastoidectomy was performed in four cases of unilateral cholesteatoma with sclerotic mastoid. During the first-stage operation, small fragments of autologous cortical bone were inserted into the cavity after mastoidectomy to form a honeycomb-like structure. Reconstruction of the lateral wall of the mastoid cavity was performed using the mastoid cortical bony plate. Pre- and postoperative mastoid volume was evaluated by three-dimensional reconstruction based on high-resolution computed tomography (HR-CT) images. Results: HR-CT images after the first-stage operation showed that mastoid volume had increased in all subjects. Macroscopic inspection during the second-stage operation revealed that the honeycomb-like structure made of bony fragments and covered by thin mucosa in the mastoid cavity was stable, with no evidence of effusion or granulation tissue. No retraction of the eardrum, middle ear effusion or recurrence of cholesteatoma was observed, and the hearing level on a pure-tone audiogram was improved in any subject 60 - 94 months after the second-stage operation. Conclusion: Surgical construction and regeneration of mastoid air cells using autologous cortical bone can be useful in treatment of cholesteatoma with arrested mastoid pneumatization.
文摘目的 观察自体乳突皮质骨粉行乳突填塞重建外耳道后壁的临床疗效。方法 43例慢性化脓性中耳炎或中耳胆脂瘤患者行乳突开放＋鼓室成形术后,应用自体乳突皮质骨粉填塞乳突术腔行外耳道后壁重建术,加耳甲腔成形术。结果 术后随访时间3~22个月,平均13.4个月;所有病例均干耳,术后干耳时间为20-56 d,平均为31.7 d。言语频率（0.5、1、2 k Hz）平均纯音听力（pure tone average,PTA）气导由术前55.0±6.2 d B提高到术后34.0±3.2 d B,骨导由术前28.1±4.4 d B提高到术后21.5±4.1 d B,气骨导差（air-bone gap,ABG）由术前26.8±7.8 d B缩小到12.5±4.1 d B,术后听力提高成功率（术后PTA-ABG≤20 d B）为74.4%（32/43例）。除4例出现填塞骨粉感染、散落外,术后所有患者外耳道形态接近正常解剖结构,鼓膜形态正常,无再穿孔及内陷袋形成,外耳道后壁重建成功率为90.7%（39/43例）。结论 中耳乳突开放术后应用自体乳突皮质骨粉填塞乳突术腔行外耳道后壁重建术,是缩小乳突术腔,获得近似正常的外耳道解剖形态结构的有效方法。
