On the Construction of Deepening Anti - corruption Mechanism

It needs the foundation of system and the guarantee of organizational system for anti-corruption,but it is more necessary to build and form an effective anti-corruption mechanism,so that the anti-corruption can be really put into practice. Anti-corruption mechanism refers to a organic operation system of the interaction,interconnection and constraint between the constituent elements( parts) and elements of national anti-corruption,and as a system,anti-corruption mechanism should have the characteristics of system aticness,comprehensiveness,transparency,legalization,public participation,scientific dynam ic,and internationalism. The construction of deepening anti-corruption mechanism is the need for reconstructing the ruling legitimacy of the party and the governm ent. Adhering to the principle of treating both root causes and symptoms is necessary in the construction of anti-corruption m echanism,com bating and punishing corruption is an important part of anti-corruption,and the prevention and control of corruption is the basic project of anti-corruption. Therefore,the construction of prevention and control mechanism in the anti-corruption mechanism has a more far-reaching significance.

Advances in Research on Anti-cancer Mechanism of 18β Glycyrrhetinic Acid

Glycyrrhiza uralensis Fisch has been used to treat the symptoms of organ fever, food poisoning, typhoid fever, sore throat, cough due to lung heat, children's diseases and so on since the ancient times. It is a solid Chinese herbal medicine which is good for the health. In recent years, it has been found that licorice extract also has excellent anti-cancer effect. The 18β glycyrrhetinic acid, obtained by hydrolysis of precursor glycyrrhizic acid, is a relatively efficient anti-cancer ingredient. 18β glycyrrhetinic acid can exert anti-cancer effects by inhibiting cancer cell proliferation, inducing apoptosis of cancer cells, inhibiting invasion and metastasis of cancer cells, preventing oxidation, inhibiting neovascularization, inhibiting lymphangiogenesis, and regulating hormone secretion. This paper reviewed the advances in research of the anticancer mechanism of 18β glycyrrhetinic acid, to provide a theoretical basis for future research.

Game analysis on Huaihe River anti-pollution administration mechanism and policy research

Based on the literature review of environmental anti-pollution researches, this paper analyzes the administra- tive mechanism of Huaihe River anti-pollution with game theory. Based on the quantitative analysis on three correspond- ing game models with four players including local residents, enterprises, local governments and competent authorities at higher levels, this paper demonstrates four main shortcomings of current administrative mechanism of Huaihe River anti-pollution system, including low emission cost, low connivance cost, overemphasis on heavy fine of the enterprises, neglect of the punishment on the local departments and intersected administrative mechanism. This paper sets up anti- pollution administrative mechanism, combining economic method with noneconomic method, government control with market mechanism, and introducing public participation. At last, this paper proposes policies, such as implementing emissions trading system, reforming public participation system, and reforming government’s environmental protection mechanism to promote law enforcement.

Study on Galloping Stability Mechanism of Conductor and Its Application to Anti-Galloping of Transmission Lines

Galloping of conductor is a major hazard to safe operation of transmission lines. This paper introduces the basic galloping stability mechanism of conductor, design method of anti-galloping and the application of anti-galloping double pendulum and integral eccentric pendulum in China. Galloping stability mechanism of conductor was established based on vertical galloping mechanism developed by Den Hartog and torsional galloping mechanism developed by O. Nigel. A design method of anti-galloping was derived and anti-galloping double pendulum and integral eccentric pendulum were developed. Applications to several transmission lines including a 500 kV transmission line of large span indicated that they have played important roles in anti-galloping.

Anti-oxidation mechanism of SiC-B_4C-C composites

Mixture of green petroleum coke, B4C and SiC together with short carbon fiber were employed as starting materials, the mixture was press-formed without any binder after grinding, dense and homogeneous binderless SiC-B4C-C（carbon/ceramic） composites were then obtained after sintering. Composites thus prepared possess excellent anti-oxidation property, that is, mass loss less than 1% within the temperature range from 900 to 1100℃ for 10h. Anti-oxidation mechanism was also discussed from the viewpoint of thermodynamics, excellent anti-oxidation property of materials thus prepared can be discribed to 1) solid SiO2 formed from SiC, which restrains the filtering of oxygen and simultaneously, its volume expansion brought about by the reaction takes roles both walling up the （original） pores and making the material more compact; 2) liquid B2O3 from the reaction of B4C not only makes the combination with C, B4C and SiC tighter through forming solid solution, but also effect of reaction SiC（s）+2CO（g）=SiO2（s）+3C（s） is an expansive process, which improves the microstructure of the material.

Study about anti-request design of transmission mechanism in job device of colliery sump cleaner

The paper takes reversal hexagon connecting bar mechanism which uses in colliery sump cleaner as research object, takes main performance of reversal hexagon connecting bar in loader as target and uses the idea of anti request project and modern design, raises a new method of engineering design. It has proved that the method is feasibility and correct by practice.

Anti-Fertility Effects and Mechanism of the Plant Extract Shikonin on Mice

Controlling fertility of rodent pests has become an effective means of controlling the population of grassland rodents in China. Recently, research has focused on how to select environmentally-friendly sterilants without pollution effects, and to realize sustainable control of pest rodent populations. Sterilants from plant extracts have been mainly selected. In this study, mice were used as the experimental subjects for research on the anti-fertility effects of plant extracts of shikonin and the anti-fertility mechanism of shikonin extract was determined. The mice were divided into four groups, including one control group and three experimental groups. There were three applications of shikonin extract in different concentrations (5 mg·kg-1, 20 mg·kg-1 and 50 mg·kg-1). The mice gavage experiments indicated that a shikonin concentration of 50 mg·kg-1 had the expected anti-fertility effects. Mice copulation experiments showed that the 50 mg·kg-1 shikonin treatment had significant anti-fertility effects on both female-treatment and female-male-treatment groups. The results of the PCR analysis on the AgRP and ghrelin mRNA from female ovaries and male testicles indicated that shikonin could control mice reproduction by regulating the pituitary gonadal axis. Shikonin, as plant source sterile agent, would have more ideal effects for functioned both sexes sterility.

Design and Analysis of Electro-mechanical Hybrid Anti-lock Braking System for Hybrid Electric Vehicle Utilizing Motor Regenerative Braking

Braking on low adhesion-coefficient roads, hybrid electric vehicle＇s motor regenerative torque is switched off to safeguard the normal anti-lock braking system （ABS） fimction. When the ABS control is terminated, the motor regenerative braking is readmitted. Aiming at avoiding permanent cycles from hydraulic anti-lock braking to motor regenerative braking, a novel electro-mechanical hybrid anti-lock braking system using fuzzy logic is designed. Different from the traditional single control structure, this system has a two-layered hierarchical structure, The first layer is responsible for harmonious adjustment or interaction between regenerative system and anti-lock braking system. The second layer is responsible for braking torque distribution and adjustment. The closed-loop simulation model is built. Control strategy and method for coordination between regenerative and anti-lock braking are developed. Simulation braking on low adhesion-coefficient roads with fuzzy logic control and real vehicle braking field test are presented. The results from simulating analysis and experiment show braking performance of the vehicle is perfect, harmonious coordination between regenerative and anti-lock braking function, significant amount of braking energy can be recovered and the proposed control strategy and method are effective.

Numerical simulation of solid tumor angiogenesis with Endostatin treatment:a combined analysis of inhibiting effect of anti-angiogenic factor and micro mechanical environment of extracellular matrix

To investigate the influence of anti-angiogenesis drug Endostatin on solid tumor angiogenesis, a mathematical model of tumor angiogenesis was developed with combined influences of local extra-cellular matrix mechanical environment, and the inhibiting effects of Angiostatin and Endostatin. Simulation results show that Angiostatin and Endostatin can effectively inhibit the process of tumor angiogenesis, and decrease the number of blood vessels in the tumor. The present model could be used as a valid theoretical method in the investigation of anti-angiogenic therapy of tumors.

Numerical investigation of unsteady mixing mechanism in plate film cooling

A large-scale large eddy simulation in high performance personal computer clusters is carried out to present unsteady mixing mechanism of film cooling and the development of films. Simulation cases include a single-hole plate with the inclined angle of 30° and blowing ratio of 0.5, and a single-row plate with hole-spacing of 1.5D and 2D （diameters of the hole）. According to the massive simulation results, some new unsteady phenomena of gas films are found. The vortex system is changed in different position with the development of film cooling with the time marching the process of a single-row plate film cooling. Due to the mutual interference effects including mutual exclusion, a certain periodic sloshing and mutual fusion, and the structures of a variety of vortices change between parallel gas films. Macroscopic flow structures and heat transfer behaviors are obtained based on 20 million grids and Reynolds number of 28600.

利用SRV试验机研究温度对润滑剂摩擦学性能的影响

介绍了一种自行研究建立的测定润滑剂抗擦伤失效温度的试验方法,这是摩擦学领域性能评价的一个新发展。利用该试验方法评价了几种润滑剂摩擦因数随温度变化的情况并确定抗擦伤失效温度,对典型样品摩擦学性能随温度变化的情况进行了机理探讨,以期为相关润滑剂研发人员提供帮助和指导。

麦冬抗肿瘤作用机制研究进展

麦冬是我国的传统中药,具有养阴生津、润肺清心的功效。越来越多的研究发现,麦冬除了传统功效外还具有对多种肿瘤的抑制作用。麦冬可通过抑制肿瘤细胞增殖、诱导肿瘤细胞凋亡、坏死性凋亡、铁死亡、焦亡、自噬、细胞周期阻滞、抑制肿瘤细胞转移和血管生成以及逆转肿瘤细胞耐药性等多种机制发挥抗肿瘤作用。对近年来麦冬块根提取物及其活性单体的抗肿瘤作用研究进展进行综述,为麦冬抗肿瘤的深入研究和对麦冬的进一步开发利用提供可借鉴的思路和方向。

道路沥青紫外老化及抗老化材料研究综述

道路沥青材料在使用过程中由于长期受到太阳光紫外辐射作用会产生紫外老化现象,并且这种现象在紫外辐射强度高的地区更明显。紫外老化会使沥青的物理特性和化学组成发生改变,从而导致沥青黏塑性上升、低温和疲劳性能下降、使用裂缝增加,进而劣化路面的耐久性、影响沥青路面的运营品质和服役寿命。为了防止和延缓紫外老化的产生和发展,可在道路沥青中添加抗老化材料以增强其抵御紫外老化能力,同时延长沥青路面的使用寿命并降低其性能的衰变速率。本文阐述了基于自由基和胶体理论的紫外老化机理;从处理方式、光源与辐射强度选择等方面介绍了室内模拟老化试验条件;总结了紫外老化对沥青物理和流变性能、组分构成、微观形貌、特征峰和官能团等宏微观特性的影响;归纳了现行抗老化材料的优缺点和使用情况。分析表明后期可在老化机理深度、试验方法标准化、室外老化监测、微观数值模拟、抗紫外老化剂针对性和抑制紫外老化措施等方面开展进一步研究。

植酸/茶多酚整理棉织物的阻燃及防紫外线性能

为解决棉织物易燃烧和抗紫外线性能差的问题,提高其使用安全性,采用浸轧和喷涂结合的方法,通过植酸(PA)和茶多酚(Tea)协同作用制备了阻燃/抗紫外线棉织物,并研究了其阻燃、防紫外线、拉伸以及透气性性能。结果表明:质量分数2.5%的PA和25 g/L的Tea复合整理的棉织物,其质量增加率仅为13.3%,而极限氧指数LOI值从原棉织物的17.5%提高到30.4%,离火自熄;PA/Tea整理棉织物与原棉织物相比,不仅热释放速率峰值(PHRR)下降了78.2%,其总热释放量(THR)和热释放能力(HRC)也分别下降了70.8%和78.3%,这意味着PA/Tea整理棉织物可以降低火灾放热强度,阻碍火焰快速传播;整理后的棉织物对UVB和UVC区域的紫外线具有良好的吸收性能,在实现阻燃和防紫外线功能的同时,保留了85.1%以上的透气性。

中药抗电离辐射药理作用及机制研究进展

中药具有高效、低毒、多靶点、特异性强等特点,其在辐射防护方面有着独特的优点。基于辐射对机体中免疫系统、造血系统和生殖系统的相关细胞及其通路损伤,以及DNA损伤和抗氧化应激,本文论述了近十年来中药及其复方抗辐射药理作用及机制的研究进展,并提出现有研究存在的问题,以期为后续新型辐射防护剂的中药产品开发提供参考。

炭黑/废纸导电纤维的制备及其在聚丙烯中的应用

利用多巴胺氧化自聚合将炭黑粘附到废纸纤维表面,制备了炭黑/废纸柔性导电纤维,分析了炭黑含量对纤维导电性能的影响,然后,将该导电纤维与聚丙烯熔融共混制备复合材料,分析了导电纤维添加量对复合材料导电和力学性能的影响。结果表明,聚多巴胺将炭黑均匀粘附在废纸纤维表面,纤维的电阻率随着炭黑含量增加而逐渐降低,当炭黑含量为15%时,废纸纤维的电阻率logρ下降至2.16Ω·cm。柔性导电纤维能更好地控制聚丙烯复合材料电导率降低幅度,当纤维添加量为15%(炭黑含量为2.27%)时,复合材料的表面电阻率为3.71×10^(10)Ω,体积电阻率为2.45×10^(11)Ω·cm,能达到抗静电级别。此时,复合材料的弹性模量和拉伸强度分别为565.65和17.01 MPa,模量提高了1.07%,但强度降低了32.82%。

改进YOLOv7的城市小型无人机目标检测方法

针对“低小动”无人机的反制技术已成为低空空域安全防御的重要手段,然而实时检测与准确识别是实施有效反制的前提条件与关键基础。针对城市低空环境下,目标检测算法对不同背景下小尺度无人机目标检测精度低,容易出现漏检误检且易受外界因素干扰等问题,提出了一种基于改进YOLOv7的“低小动”无人机目标检测方法。首先采集大量不同环境、不同背景下的无人机样本构建数据集,并采用ViBe(visual background extractor)算法进行预处理;其次引入坐标注意力机制与SPDConv(space-to-depth convolution)模块改进和优化YOLOv7的网络结构;最后提出融合ViBe和改进YOLOv7的二级检测架构,将改进后的YOLOv7作为网络模型检测经ViBe处理后的图像。依据原图与处理图像的位置大小关系,将检测出的目标坐标映射回归至原图片,从而完成目标检测提取。实验结果表明,所提目标检测方法检测精度达96.5%,较原YOLOv7方法提高了15.8个百分点,显著提升了“低小动”目标的检测精度,能够满足低空无人机的实时精准检测的需求。

荔枝落果中A型低聚原花青素抑制类甜蛋白促炎机制

以荔枝落果中的A型低聚原花青素为研究对象,探讨其对荔枝类甜蛋白(litchi thaumatin-like protein,LcTLP)促炎的抑制机理。采用乙醇提取、大孔吸附树脂纯化以及制备液相色谱仪等从荔枝落果中分离得到A型低聚原花青素(A-type oligomeric proanthocyanidins,A-OPC)纯化物,并对A-OPC结构鉴定,主要成分为原花青素A2、2个A型原花青素三聚体和1个A型四聚体,纯度达88.69%。利用LcTLP诱导构建RAW264.7细胞炎症模型,A-OPC的添加可抑制LcTLP诱导RAW264.7细胞的一氧化氮、细胞炎症因子白细胞介素-6和肿瘤坏死因子-α的分泌,在120μg/mL质量浓度下,抑制率分别可达58.38%、39.80%和86.31%(P<0.01)。蛋白免疫印迹分析发现,在120μg/mL质量浓度下A-OPC可降低诱导型一氧化氮合酶和环氧合酶2的表达量,并显著降低p65、核因子κB抑制蛋白、c-Jun氨基末端激酶、细胞外信号调节蛋白激酶和p38的磷酸化水平,说明A-OPC通过下调核转录因子-κB和丝裂原活化蛋白激酶通路中下游蛋白的磷酸化水平抑制LcTLP诱导的炎症反应。

基于空闲时隙探测机制的分组帧时隙标签防碰撞算法

多标签碰撞是射频识别系统中无法避免的问题,大量的标签碰撞会增加系统的能量消耗和时间开销,严重影响系统的识别效率。为此提出一种新型的标签防碰撞算法,该算法结合了传统帧时隙算法简单易实施的优点,同时引入了分组和空闲时隙探测机制,以极小的探测时隙开销,消除了识别过程中的空闲时隙,同时减低了标签冲突概率。仿真结果显示,相对于FuzzyQ算法和帧时隙ALOHA算法,本算法平均吞吐率提高了22.64%和61.74%,系统通信传输量平均节省了16.73%和30.41%。