Hydrocarbon Generation Potential and Organic Matter Enrichment Mechanism of the Cambrian Marine Shale in the Tadong Low Uplift,Tarim Basin

Cambrian shales in China and elsewhere contain abundant oil and gas resources.However,due to its deep burial and limited outcrop,there has been relatively little research conducted on it.The Cambrian shale of the Tadong low uplift in the Tarim Basin of western China,specifically the Xidashan-Xishanbulake Formation(Fm.)and overlying Moheershan Fm.provide a case study through the use of organic petrology,mineralogy,organic and elemental geochemistry,with the aim of analyzing and exploring the hydrocarbon generation potential(PG)and organic matter(OM)enrichment mechanisms within these shale formations.The results indicate that:(1)the Cambrian shale of the Tadong low uplift exhibits relatively dispersed OM that consists of vitrinite-like macerals and solid bitumen.These formations have a higher content of quartz and are primarily composed of silica-based lithology;(2)shale samples from the Xidashan-Xishanbulake and Moheershan formations demonstrate high total organic carbon(TOC)and low pyrolytic hydrocarbon content(S_(2))content.The OM is predominantly typeⅠand typeⅡkerogens,indicating a high level of maturation in the wet gas period.These shales have undergone extensive hydrocarbon generation,showing characteristics of relatively poor PG;(3)the sedimentary environments of the Xidashan-Xishanbulake and Moheershan formations in the Tadong low uplift are similar.They were deposited in warm and humid climatic conditions,in oxygen-deficient environments,with stable terrigenous inputs,high paleoproductivity,high paleosalinity,weak water-holding capacity,and no significant hydrothermal activity;and(4)the relationship between TOC and the paleoproductivity parameter(P/Ti)is most significant in the Lower Cambrian Xidashan-Xishanbulake Fm.,whereas correlation with other indicators is not evident.This suggests a productivity-driven OM enrichment model,where input of landderived material was relatively small during the Middle Cambrian,and the ancient water exhibited lower salinity.A comprehensive pattern was formed under the combined control of paleoproductivity and preservation conditions.This study provides valuable guidance for oil and gas exploration in the Tarim Basin.

Deep Insight of Design,Mechanism,and Cancer Theranostic Strategy of Nanozymes

Since the discovery of enzyme-like activity of Fe3O4 nanoparticles in 2007,nanozymes are becoming the promising substitutes for natural enzymes due to their advantages of high catalytic activity,low cost,mild reaction conditions,good stability,and suitable for large-scale production.Recently,with the cross fusion of nanomedicine and nanocatalysis,nanozyme-based theranostic strategies attract great attention,since the enzymatic reactions can be triggered in the tumor microenvironment to achieve good curative effect with substrate specificity and low side effects.Thus,various nanozymes have been developed and used for tumor therapy.In this review,more than 270 research articles are discussed systematically to present progress in the past five years.First,the discovery and development of nanozymes are summarized.Second,classification and catalytic mechanism of nanozymes are discussed.Third,activity prediction and rational design of nanozymes are focused by highlighting the methods of density functional theory,machine learning,biomimetic and chemical design.Then,synergistic theranostic strategy of nanozymes are introduced.Finally,current challenges and future prospects of nanozymes used for tumor theranostic are outlined,including selectivity,biosafety,repeatability and stability,in-depth catalytic mechanism,predicting and evaluating activities.

Evolution mechanism and treatment timing of penetrating fissures

The Inner Mongolia mining area in western China are characterized by the development of numerous penetrating fissures,resulting in severe land damage.It is significant to reveal the underlying evolution mechanism and identify treatment timing for restoring the ecological environment.The Guanbanwusu mining subsidence area in Inner Mongolia,China was selected as the research case for this study.The evolution mechanism of different penetrating fissures was revealed by field measurement,physical simulation and theoretical analysis.The treatment timing prediction model for the mining subsidence area was established based on the enhanced Weibull time function.The results show that the ground fissures are mainly step-type and collapse-type fissures.The breaking form of overlying strata determines their vertical opening and horizontal dislocation.The high mining intensity in the western mining area results in a shortened period of dynamic fissure expansion and reduced closure degree.The damage extent of the overlying strata exhibits zoning characteristics both vertically and horizontally.The relative standard deviation of the prediction model is only 3.7%.Concurrently,the prediction model is employed to determine the optimal timing for treatment in the study area,estimated to be 259 days.Subsequently,once this threshold is reached,the study area undergoes treatment and restoration of its e cological environment.This study addresses the knowledge gap in this field by highlighting the interconnectedness between rock strata structure and evolution mechanism of penetrating fissures,thereby providing a method for determining the treatment timing in mining subsidence areas.

Exploring the mechanism of action of herb pair Pinellia Ternata-Magnolia Officinalis in the treatment of liver cancer based on network pharmacology and molecular docking

Background:Explore the anti-tumor mechanism of herb pair Pinellia ternate-Magnolia officinalis(BX-HP)in liver cancer through network pharmacology using molecular docking methods.Method:The active ingredients and corresponding targets of the herb pair Pinellia ternate-Magnolia officinalis were obtained from the HERB database.The relevant targets for liver cancer were obtained from GeneCards,DisGeNET,TTD,and Drugbank databases.Obtain common targets between herb pair Pinellia ternate-Magnolia officinalis and liver cancer through the Bioinformatics platform,establish a PPI network diagram using STRING software,and perform GO functional enrichment and KEGG pathway enrichment analysis on the DAVID platform.AutoDockTools 1.5.7 software and molecular dynamics simulation analysis are used to evaluate the binding of components to target proteins.HERB database,SwissTargetPrediction database,SwissADME database,UniProt database,GeneCards database,TTD database,DRUGBANK database,DisGeNET database,String,DAVID.Bioinformatics platform,PDB database,PubChem and TCMSP database.Result:A total of 22 active ingredients with a Probability>0.1 targets in Magnolia officinalis were screened,26 active ingredients with a Probability>0.1 targets in Pinellia ternata,ten vital active ingredients,corresponding to 979 and 803 targets with a Probability>0.1 targets,2536 liver cancer-related targets,and 279 targets in the herb pair Pinellia ternata-Magnolia officinalis.The GO functional enrichment analysis resulted in 1297 entries,namely 971 biological process entries,118 cell localization entries,and 208 molecular function entries.Three signaling pathways were annotated through the KEGG pathway.Based on molecular docking,ten vital active ingredients and five target proteins were validated to exhibit an excellent binding affinity.The above data indicates that combining the herb pair Pinellia ternata-Magnolia officinalis may treat liver cancer through specific targets and signaling pathways.Conclusion:Herb pair Pinellia ternata-Magnolia officinalis has a synergistic effect on treating liver cancer through multicomponent,multitarget,and multi-pathway approaches.This study provides a sufficient theoretical basis for subsequent research.

On the Geodynamic Mechanism of Episodic Uplift of the Tibetan Plateau during the Cenozoic Era

Multi-stage uplift of the Tibetan Plateau during the Cenozoic implies a complex geodynamic process.In this paper,we review main geodynamic models for the uplift of the plateau,and,in particular,analyze the spatio-temporal framework of the Cenozoic deformation structures,which are closely related to the deep geodynamic mechanism for the plateau uplift.From this perspective,significant change of the deformation regime over the Tibetan Plateau occurred by the middle-late Miocene,while thrust and thrust-folding system under NS compression was succeded by extension or stress-relaxation.Meanwhile,a series of large-scale strike-slip faults commenced or was kinemtically reversed.Based on a systematic synthesis of the structure deformation,magmatism,geomorphological process and geophysical exploration,we propose a periodical model of alternating crustal compression and extension for episodic uplift of the Tibetan Plateau.

Seismological method for prediction of areal rockbursts in deep mine with seismic source mechanism and unstable failure theory

The research on the rock burst prediction was made on the basis of seismology,rock mechanics and the data from Dongguashan Copper Mine(DCM) ,the deepest metal mine in China.The seismic responses to mining in DCM were investigated through the analyses of the spatio-temporal distribution of hypocenters,apparent stress and displacement of seismic events,and the process of the generation of hazardous seismicity in DCM was studied in the framework of the theory of asperity in the seismic source mechanism.A method of locating areas with hazardous seismicity and a conceptual model of hazardous seismic nucleation in DCM were proposed.A criterion of rockburst prediction was analyzed theoretically in the framework of unstable failure theories,and consequently,the rate of change in the ratio of the seismic stiffness of rock in a seismic nucleation area to that in surrounding area,dS/dt,is defined as an index of the rockburst prediction.The possibility of a rockburst will increase if dS/dt>0,and the possibility of rock burst will decrease if dS/dt<0.The correctness of these methods is demonstrated by analyses of rock failure cases in DCM.

Interacting mechanism and initiation prediction of multiple cracks

The maximum Mode Ⅰ and Mode Ⅱ stress intensity factors(SIFs), KI,kmax(θ) and KII,kmax(θ)(0°<θ<360°), of inclined parallel multi-crack varying with relative positions(including horizontal and vertical spacings) are calculated by the complex function and integration method to analyze their interacting mechanism and determine the strengthening and weakening zone of SIFs. The multi-crack initiation criterion is established based on the ratio of maximum tension-shear SIF to predict crack initiation angle, load, and mechanism. The results show that multi-crack always initiates in Mode Ⅰ and the vertical spacing is better not to be times of half crack-length for crack-arrest, which is in good agreement with test results of the red-sandstone cube specimens with three parallel cracks under uniaxial compression. This can prove the validity of the multi-crack initiation criterion.

Uplift behavior and load transfer mechanism of prestressed high-strength concrete piles

Prestressed high-strength-concrete (PHC) tube-shaped pile is one of the recently used foundations for soft soil. The research on uplift resistance of PHC pile is helpful to the design of pile foundations. A field-scale test program was conducted to study the uplift behavior and load transfer mechanism of PHC piles in soft soil. The pullout load tests were divided into two groups with different diameters, and there were three piles in each group. A detailed discussion of the axial load transfer and pile skin resistance distribution was also included. It is found from the tests that the uplift capacity increases with increasing the diameter of pile. When the diameter of piles increases from 500 to 600 mm, the uplift load is increased by 51.2%. According to the load-displacement (Q-S) curves, all the piles do not reach the ultimate state at the maximum load. The experimental results show that the piles still have uplift bearing capacity.

Prediction model of slurry pH based on mechanism and error compensation for mineral flotation process

A suitable pH value of the slurry is a key to efficient mineral flotation. Considering the control delay problem of pH value caused by offline pH measurement, an integrated prediction model for pH value in bauxite froth flotation is proposed, which considers the effect of ore compositions on pH value. Firstly, a regression model is obtained for alkali(Na_2CO_3) consumed by the reaction between ore and alkali. According to the first-order hydrolysis of the remaining alkali, a mechanism-based prediction model is presented for the pH value. Then, considering the complexity of the flotation mechanism, an error prediction model which uses time series of the error of the mechanism model as inputs is presented based on autoregressive moving average(ARMA) method to compensate the mechanism model. Finally, expert rules are established to correct the error compensation direction, which could reflect the dynamic changes during the process accurately and effectively. Simulation results using industrial data show that the presented model meets the needs of the industrial process, which laid the foundation for predictive control of pH regulator.

Prediction of Henry Constants and Adsorption Mechanism of Volatile Organic Compounds on Multi-Walled Carbon Nanotubes by Using Support Vector Regression

Support vector regression （SVR） combined with particle swarm optimization for its parameter optimization is employed to establish a model for predicting the Henry constants of multi-walled carbon nanotubes （MWNTs） for adsorption of volatile organic compounds （VOCs）. The prediction performance of SVR is compared with those of the model of theoretical linear salvation energy relationship （TLSER）. By using leave-one-out cross validation of SVR test Henry constants for adsorption of 35 VOCs on MWNTs, the root mean square error is 0.080, the mean absolute percentage error is only 1.19~, and the correlation coefficient （R2） is as high as 0.997. Compared with the results of the TLSER model, it is shown that the estimated errors by SVR are ali smaller than those achieved by TLSER. It reveals that the generalization ability of SVR is superior to that of the TLSER model Meanwhile, multifactor analysis is adopted for investigation of the influences of each molecular structure descriptor on the Henry constants. According to the TLSER model, the adsorption mechanism of adsorption of carbon nanotubes of VOCs is mainly a result of van der Waals and interactions of hydrogen bonds. These can provide the theoretical support for the application of carbon nanotube adsorption of VOCs and can make up for the lack of experimental data.

The Formation Mechanism and Geological Significance of Fluorite in Ordovician, Central Uplift of Tarim Basin

Based on analysisof karst fracture-vuggy filling mineralogy and geochemical fluorite in hercynian, this paper make further research about formation and significance of fluorite in central uplift of Tarim Basin. It is point out that the development of hercynian fracture-vuggy and filling succession of fracture-cave mineral was under the background of the mingling of low-temperature magma hydrotherm and the brine of upper strata. There are overlap or associate relations between generate of fluorite and buried dissolution or oil-gas migration. It was volume decreased 26.4% after calcite metasomatic by fluorite, this reaction made fluorite engender plentiful intergranular space. It’s created appreciable reservoir space. At same time, hydrotherm carried by fluorite generating could erode adjacent rock though fracture or fissure, forming irregular fracture-cave system, and also accompanied with hydrocarbon migration. The time of hydrocarbon migration and accumulation happened in late hercynian-indosinian is inosculates with the sedimentation time such as fluorite and several hydrothermal mineral.

Ceramic particles reinforced copper matrix composites manufactured by advanced powder metallurgy:preparation, performance, and mechanisms

Copper matrix composites doped with ceramic particles are known to effectively enhance the mechanical properties,thermal expansion behavior and high-temperature stability of copper while maintaining high thermal and electrical conductivity.This greatly expands the applications of copper as a functional material in thermal and conductive components,including electronic packaging materials and heat sinks,brushes,integrated circuit lead frames.So far,endeavors have been focusing on how to choose suitable ceramic components and fully exert strengthening effect of ceramic particles in the copper matrix.This article reviews and analyzes the effects of preparation techniques and the characteristics of ceramic particles,including ceramic particle content,size,morphology and interfacial bonding,on the diathermancy,electrical conductivity and mechanical behavior of copper matrix composites.The corresponding models and influencing mechanisms are also elaborated in depth.This review contributes to a deep understanding of the strengthening mechanisms and microstructural regulation of ceramic particle reinforced copper matrix composites.By more precise design and manipulation of composite microstructure,the comprehensive properties could be further improved to meet the growing demands of copper matrix composites in a wide range of application fields.

Mechanism and Distribution of Calcareous Interbeds in Songtao Uplift and Its Periphery of Qiongdongnan Basin

Based on core and casting slice observation, well drilling and logging data, the source of carbonate materials, lithology together with electric properties, types, genesis mechanism and distribution of calcareous interbeds in Songtao uplift and its periphery of Qiongdongnan Basin have been thoroughly analyzed. Results show that typical features have been appeared from well logging curves, containing low gamma-ray, low acoustic travel time, low neutron value, high density, as well as bright white calcium nodules or bands in electrical imaging well-logging curves. Drilling results reveal that calcareous interbeds developed mostly in high position of paleostructures and their distribution was controlled by the combined effects of macroscopic and microscopic factors. Macroscopically, calcareous interbeds relate to paleogeomorphology together with the combination of sandstone and mudstone. They are also controlled microscopically by the source of carbonate cements and pore space. Under normal circumstances, with regard to the same sand, the closer to the mudstone and the thicker of mudstone, the more conducive to the formation of calcareous interlayer. Low compaction strength, high content of rigid particles, coarse grain size, well-sorted sandstone and large pore space during carbonate cementation are favorable for the development of calcareous interbeds.

Accelerated Deterioration Mechanism and Reliability Evaluation of Concrete in Saline Soil Area

To reveal the deterioration mechanism and service life of concrete durability in the western saline soil area,the indoor accelerated test of the concrete specimen was simulated in the coupled environment of salt erosion and dry-wet cycles in the west saline soil area of China.The deterioration mechanism of concrete durability was revealed through the relative dynamic elastic modulus,relative quality evaluation parameters,SEM,and XRD evaluation indexes.Random Wiener distribution function was used for modeling life prediction.The results show that the relative dynamic elastic modulus evaluation parameter as an evaluation index of concrete durability under various environmental coupling effects is more reliable than the relative quality,there were holes and cracks in the concrete,and needle-like and layered crystals grow from the internal cracks.The corrosion products include ettringite,gypsum and other expansive crystals and non-gelling Mg(OH)_(2);the expansion stress caused by physical,chemical reaction,and temperature change under the action of drywet cycle aggravates the formation and development of cracks.The random Wiener distribution function can describe the degradation process of concrete specimen durability,and the established concrete reliability function can intuitively reflect the service life of concrete specimens.

Dissolution mechanism of a deep-buried sandstone reservoir in a deep water area:A case study from Baiyun Sag,Zhujiang River(Pearl River)Mouth Basin

Dissolution mechanism and favorable reservoir distribution prediction are the key problems restricting oil and gas exploration in deep-buried layers.In this paper,the Enping Formation and Zhuhai Formation in Baiyun Sag of South China Sea was taken as a target.Based on the thin section,scanning electron microscopy,X-ray diffraction,porosity/permeability measurement,and mercury injection,influencing factors of dissolution were examined,and a dissolution model was established.Further,high-quality reservoirs were predicted temporally and spatially.The results show that dissolved pores constituted the main space of the Paleogene sandstone reservoir.Dissolution primarily occurred in the coarse-and medium-grained sandstones in the subaerial and subaqueous distributary channels,while dissolution was limited in fine-grained sandstones and inequigranular sandstones.The main dissolved minerals were feldspar,tuffaceous matrix,and diagenetic cement.Kaolinization of feldspar and illitization of kaolinite are the main dissolution pathways,but they occur at various depths and temperatures with different geothermal gradients.Dissolution is controlled by four factors,in terms of depositional facies,source rock evolution,overpressure,and fault activities,which co-acted at the period of 23.8–13.8 Ma,and resulted into strong dissolution.Additionally,based on these factors,high-quality reservoirs of the Enping and Zhuhai formations are predicted in the northern slope,southwestern step zone,and Liuhua uplift in the Baiyun Sag.

CHARACTERIZATION AND FORMATION MECHANISM OF THE CENTRAL UPLIFT OF THE QIANGTANG BASIN

The Qiangtang basin is located between Kekexili-Jingshajiang suture belt and Bangong-Lujiang suture belt, and is divided into the north part and south part by the central uplift that has no crop out of Mesozoic strata. When the Jinshajiang Ocean was closed, the subducting plate was subducted southward. In the central part of the Qiangtang basin, the cushioning effect of the asthenosphere resulted in the thermal doming of the mantle and subsequent large-scale anatexis. Mantle source materials and antectic materials were upwelled and extruded into the middle crust, leading to the thickening of the middle crust and the heating and weakening of the middle to upper crust, and resulting in the rapid deformation (detachment) and tectonic erosion, and in the isostatic uplifting and the formation of metamorphic core complex. The upwelling of anatectic materials would further enhance the buoyant repercussion, which would combine with the side stress due from extrusion in resulting in the formation of an extensional stress field. The extensional structure and detachment fault are formed under the influence of the losing stabilized gravitation. In the deformation area in both the upper part and the lower part, an extensional deposition area would be formed, and this is the generation of a new basin.The metamorphic core complex of the central uplift is comprised of gneiss, which is itself overlain by non-metamorphic to weakly metamorphic covering strata intersected by faults.

MECHANISM AND HISTORICAL BACKGROUND OF THE UPLIFT OF THE QINGHAI-XIZANG(TIBET) PLATEAU

The uplift of the Qinghai-Xizang (Tibet) Plateau happened in a different crustal movementsand different time from those of the collision of Asia continent with the allochthonous India crusto-body, and the uplift occurred very long after the finish of the collision. In fact, there are no direct-ly causationic relationships in time and dynamics, as well as in crustobody movement nature be-tween the uplift and collision. According to its temporal evolution, the uplift happened in anotheractive stage of the mantle creep flow after the active stage resulting in the collision and the inter-ruption of the 140 Ma’s quiet stage-particularly noticeably after this interruption of quiet stage-resulting in the universal Qinghai-Xizang (Tibet) ancient platform. On the basis of the dynamicanalysis, the uplift resulted from the multiple compressing stresses in the reactivation stage afterweakening of the colliding stress and the following compressing stress, and after the interruptionof the stable stage dominating the vertical movements and represented by fomation of the universalQinghai-Xizang (Tibet) ancient platform. It was the production of another stress field existing inanother crustobody evolution stage and growth age. In the light of the nature of the orogeny, theuplift was caused by the intracontinental diwa (geodepression)-type orogeny after converging con-nection of the Centra1 Asia Crustobody and the India Crustobody.Because of the big temporal difference between the uplift and collision events, the so-calleddouble-crust hypothesis of the Qinghai-Xizang (Tibet) Plateau may not be realistic.

CNN-LSTM based on attention mechanism for brake pad remaining life prediction

In order to predict the remaining service life of brake pads accurately and efficiently,and to achieve intelligent warning,this paper proposes a CNN-LSTM brake pad remaining life prediction model based on an attention mechanism.The model constructs a non-linear relationship between brake pad features such as brake temperature,brake oil pressure and brake speed and brake pad wear data through convolutional neural network(CNN)and long and short term memory network(LSTM),as well as capturing the time dependence that exists in the brake pad wear sequence.The attention mechanism is also introduced to assign different weight values to the features output from multiple historical moments,highlighting the features with high saliency and avoiding the influence of invalid features,so as to improve the prediction effect of the remaining brake pad life.The results show that the proposed CNN-LSTM-Attention model can effectively predict the remaining life of brake pads,with the mean absolute error MAE value of 0.0048,root mean square error RMSE value of 0.0059 and coefficient of determination R2 value of 0.9636;and compared with the BP model,CNN model,LSTM model and CNN-LSTM model,the coefficient of determination R2 values are closest to 1,with an improvement of 8.26%,5.25%,3.99%and 1.85%respectively,enabling more effective monitoring and intelligent warning of the remaining brake pad life.

Experimental study on uplift mechanism of pipeline buried in sand using high-resolution fiber optic strain sensing nerves

Reliable assessment of uplift capacity of buried pipelines against upheaval buckling requires a valid failure mechanism and a reliable real-time monitoring technique.This paper presents a sensing solution for evaluating uplift capacity of pipelines buried in sand using fiber optic strain sensing(FOSS)nerves.Upward pipe-soil interaction(PSI)was investigated through a series of scaled tests,in which the FOSS and image analysis techniques were used to capture the failure patterns.The published prediction models were evaluated and modified according to observations in the present study as well as a database of 41 pipe loading tests assembled from the literature.Axial strain measurements of FOSS nerves horizontally installed above the pipeline were correlated with the failure behavior of the overlying soil.The test results indicate that the previous analytical models could be further improved regarding their estimations in the failure geometry and mobilization distance at the peak uplift resistance.For typical slip plane failure forms,inclined shear bands star from the pipe shoulder,instead of the springline,and have not yet reached the ground surface at the peak resistance.The vertical inclination of curved shear bands decreases with increasing uplift displacements at the post-peak periods.At large displacements,the upward movement is confined to the deeper ground,and the slip plane failure progressively changes to the flow-around.The feasibility of FOSS in pipe uplift resistance prediction was validated through the comparison with image analyses.In addition,the shear band locations can be identified using fiber optic strain measurements.Finally,the advantages and limits of the FOSS system are discussed in terms of different levels in upward PSI assessment,including failure identification,location,and quantification.

Mining seismicity in the Witwatersrand Basin:monitoring,mechanisms and mitigation strategies in perspective

The Kaapvaal Craton in South Africa hosts one of the largest gold placer deposits in the world. Mining in the Witwatersrand Basin here has been the source of about one third to one half of the gold ever produced in the world. Gold was discovered in the Johannesburg area in 1886 and after 120 years of continuous operation, mining is currently approaching depths of 4 000 m. In spite of the challenges and risks that the industry has had to deal with including rock temperature, ventilation and water, one of the most feared hazards in the basin has been the threat from the ongoing occurrence of seismicity and rockbursts. The problem first manifested itself by way of the occurrence of tremors roughly twenty years after the commencement of mining operations. This paper traces the history of the approach to rockbursts and seismicity during the 120 year history of mining in the basin. It portrays a picture of the mining seismicity in terms of monitoring phases, mechanisms and mitigation strategies. The work of research organizations over the years is highlighted with a brief mention of current regulation strategies on the part of the mining inspectorate.