Large language models(LLMs),such as ChatGPT developed by OpenAI,represent a significant advancement in artificial intelligence(AI),designed to understand,generate,and interpret human language by analyzing extensive te...Large language models(LLMs),such as ChatGPT developed by OpenAI,represent a significant advancement in artificial intelligence(AI),designed to understand,generate,and interpret human language by analyzing extensive text data.Their potential integration into clinical settings offers a promising avenue that could transform clinical diagnosis and decision-making processes in the future(Thirunavukarasu et al.,2023).This article aims to provide an in-depth analysis of LLMs’current and potential impact on clinical practices.Their ability to generate differential diagnosis lists underscores their potential as invaluable tools in medical practice and education(Hirosawa et al.,2023;Koga et al.,2023).展开更多
The pancreas is neither part of the five Zang organs(五脏) nor the six Fu organs(六腑).Thus,it has received little attention in Chinese medical literature.In the late 19th century,medical missionaries in China started...The pancreas is neither part of the five Zang organs(五脏) nor the six Fu organs(六腑).Thus,it has received little attention in Chinese medical literature.In the late 19th century,medical missionaries in China started translating and introducing anatomical and physiological knowledge about the pancreas.As for the word pancreas,an early and influential translation was “sweet meat”(甜肉),proposed by Benjamin Hobson(合信).The translation “sweet meat” is not faithful to the original meaning of “pancreas”,but is a term coined by Hobson based on his personal habits,and the word “sweet” appeared by chance.However,in the decades since the term “sweet meat” became popular,Chinese medicine practitioners,such as Tang Zonghai(唐宗海),reinterpreted it by drawing new medical illustrations for “sweet meat” and giving new connotations to the word “sweet”.This discussion and interpretation of “sweet meat” in modern China,particularly among Chinese medicine professionals,is not only a dissemination and interpretation of the knowledge of “pancreas”,but also a construction of knowledge around the term “sweet meat”.展开更多
In the intricate network environment,the secure transmission of medical images faces challenges such as information leakage and malicious tampering,significantly impacting the accuracy of disease diagnoses by medical ...In the intricate network environment,the secure transmission of medical images faces challenges such as information leakage and malicious tampering,significantly impacting the accuracy of disease diagnoses by medical professionals.To address this problem,the authors propose a robust feature watermarking algorithm for encrypted medical images based on multi-stage discrete wavelet transform(DWT),Daisy descriptor,and discrete cosine transform(DCT).The algorithm initially encrypts the original medical image through DWT-DCT and Logistic mapping.Subsequently,a 3-stage DWT transformation is applied to the encrypted medical image,with the centre point of the LL3 sub-band within its low-frequency component serving as the sampling point.The Daisy descriptor matrix for this point is then computed.Finally,a DCT transformation is performed on the Daisy descriptor matrix,and the low-frequency portion is processed using the perceptual hashing algorithm to generate a 32-bit binary feature vector for the medical image.This scheme utilises cryptographic knowledge and zero-watermarking technique to embed watermarks without modifying medical images and can extract the watermark from test images without the original image,which meets the basic re-quirements of medical image watermarking.The embedding and extraction of water-marks are accomplished in a mere 0.160 and 0.411s,respectively,with minimal computational overhead.Simulation results demonstrate the robustness of the algorithm against both conventional attacks and geometric attacks,with a notable performance in resisting rotation attacks.展开更多
This article proposes a novel fractional heterogeneous neural network by coupling a Rulkov neuron with a Hopfield neural network(FRHNN),utilizing memristors for emulating neural synapses.The study firstly demonstrates...This article proposes a novel fractional heterogeneous neural network by coupling a Rulkov neuron with a Hopfield neural network(FRHNN),utilizing memristors for emulating neural synapses.The study firstly demonstrates the coexistence of multiple firing patterns through phase diagrams,Lyapunov exponents(LEs),and bifurcation diagrams.Secondly,the parameter related firing behaviors are described through two-parameter bifurcation diagrams.Subsequently,local attraction basins reveal multi-stability phenomena related to initial values.Moreover,the proposed model is implemented on a microcomputer-based ARM platform,and the experimental results correspond to the numerical simulations.Finally,the article explores the application of digital watermarking for medical images,illustrating its features of excellent imperceptibility,extensive key space,and robustness against attacks including noise and cropping.展开更多
In blood or bone marrow,leukemia is a form of cancer.A person with leukemia has an expansion of white blood cells(WBCs).It primarily affects children and rarely affects adults.Treatment depends on the type of leukemia...In blood or bone marrow,leukemia is a form of cancer.A person with leukemia has an expansion of white blood cells(WBCs).It primarily affects children and rarely affects adults.Treatment depends on the type of leukemia and the extent to which cancer has established throughout the body.Identifying leukemia in the initial stage is vital to providing timely patient care.Medical image-analysis-related approaches grant safer,quicker,and less costly solutions while ignoring the difficulties of these invasive processes.It can be simple to generalize Computer vision(CV)-based and image-processing techniques and eradicate human error.Many researchers have implemented computer-aided diagnosticmethods andmachine learning(ML)for laboratory image analysis,hopefully overcoming the limitations of late leukemia detection and determining its subgroups.This study establishes a Marine Predators Algorithm with Deep Learning Leukemia Cancer Classification(MPADL-LCC)algorithm onMedical Images.The projectedMPADL-LCC system uses a bilateral filtering(BF)technique to pre-process medical images.The MPADL-LCC system uses Faster SqueezeNet withMarine Predators Algorithm(MPA)as a hyperparameter optimizer for feature extraction.Lastly,the denoising autoencoder(DAE)methodology can be executed to accurately detect and classify leukemia cancer.The hyperparameter tuning process using MPA helps enhance leukemia cancer classification performance.Simulation results are compared with other recent approaches concerning various measurements and the MPADL-LCC algorithm exhibits the best results over other recent approaches.展开更多
Automatic segmentation of medical images provides a reliable scientific basis for disease diagnosis and analysis.Notably,most existing methods that combine the strengths of convolutional neural networks(CNNs)and Trans...Automatic segmentation of medical images provides a reliable scientific basis for disease diagnosis and analysis.Notably,most existing methods that combine the strengths of convolutional neural networks(CNNs)and Transformers have made significant progress.However,there are some limitations in the current integration of CNN and Transformer technology in two key aspects.Firstly,most methods either overlook or fail to fully incorporate the complementary nature between local and global features.Secondly,the significance of integrating the multiscale encoder features from the dual-branch network to enhance the decoding features is often disregarded in methods that combine CNN and Transformer.To address this issue,we present a groundbreaking dual-branch cross-attention fusion network(DCFNet),which efficiently combines the power of Swin Transformer and CNN to generate complementary global and local features.We then designed the Feature Cross-Fusion(FCF)module to efficiently fuse local and global features.In the FCF,the utilization of the Channel-wise Cross-fusion Transformer(CCT)serves the purpose of aggregatingmulti-scale features,and the Feature FusionModule(FFM)is employed to effectively aggregate dual-branch prominent feature regions from the spatial perspective.Furthermore,within the decoding phase of the dual-branch network,our proposed Channel Attention Block(CAB)aims to emphasize the significance of the channel features between the up-sampled features and the features generated by the FCFmodule to enhance the details of the decoding.Experimental results demonstrate that DCFNet exhibits enhanced accuracy in segmentation performance.Compared to other state-of-the-art(SOTA)methods,our segmentation framework exhibits a superior level of competitiveness.DCFNet’s accurate segmentation of medical images can greatly assist medical professionals in making crucial diagnoses of lesion areas in advance.展开更多
The Internet of Multimedia Things(IoMT)refers to a network of interconnected multimedia devices that communicate with each other over the Internet.Recently,smart healthcare has emerged as a significant application of ...The Internet of Multimedia Things(IoMT)refers to a network of interconnected multimedia devices that communicate with each other over the Internet.Recently,smart healthcare has emerged as a significant application of the IoMT,particularly in the context of knowledge‐based learning systems.Smart healthcare systems leverage knowledge‐based learning to become more context‐aware,adaptable,and auditable while maintain-ing the ability to learn from historical data.In smart healthcare systems,devices capture images,such as X‐rays,Magnetic Resonance Imaging.The security and integrity of these images are crucial for the databases used in knowledge‐based learning systems to foster structured decision‐making and enhance the learning abilities of AI.Moreover,in knowledge‐driven systems,the storage and transmission of HD medical images exert a burden on the limited bandwidth of the communication channel,leading to data trans-mission delays.To address the security and latency concerns,this paper presents a lightweight medical image encryption scheme utilising bit‐plane decomposition and chaos theory.The results of the experiment yield entropy,energy,and correlation values of 7.999,0.0156,and 0.0001,respectively.This validates the effectiveness of the encryption system proposed in this paper,which offers high‐quality encryption,a large key space,key sensitivity,and resistance to statistical attacks.展开更多
Gliomas have the highest mortality rate of all brain tumors.Correctly classifying the glioma risk period can help doctors make reasonable treatment plans and improve patients’survival rates.This paper proposes a hier...Gliomas have the highest mortality rate of all brain tumors.Correctly classifying the glioma risk period can help doctors make reasonable treatment plans and improve patients’survival rates.This paper proposes a hierarchical multi-scale attention feature fusion medical image classification network(HMAC-Net),which effectively combines global features and local features.The network framework consists of three parallel layers:The global feature extraction layer,the local feature extraction layer,and the multi-scale feature fusion layer.A linear sparse attention mechanism is designed in the global feature extraction layer to reduce information redundancy.In the local feature extraction layer,a bilateral local attention mechanism is introduced to improve the extraction of relevant information between adjacent slices.In the multi-scale feature fusion layer,a channel fusion block combining convolutional attention mechanism and residual inverse multi-layer perceptron is proposed to prevent gradient disappearance and network degradation and improve feature representation capability.The double-branch iterative multi-scale classification block is used to improve the classification performance.On the brain glioma risk grading dataset,the results of the ablation experiment and comparison experiment show that the proposed HMAC-Net has the best performance in both qualitative analysis of heat maps and quantitative analysis of evaluation indicators.On the dataset of skin cancer classification,the generalization experiment results show that the proposed HMAC-Net has a good generalization effect.展开更多
Deep learning has been extensively applied to medical image segmentation,resulting in significant advancements in the field of deep neural networks for medical image segmentation since the notable success of U Net in ...Deep learning has been extensively applied to medical image segmentation,resulting in significant advancements in the field of deep neural networks for medical image segmentation since the notable success of U Net in 2015.However,the application of deep learning models to ocular medical image segmentation poses unique challenges,especially compared to other body parts,due to the complexity,small size,and blurriness of such images,coupled with the scarcity of data.This article aims to provide a comprehensive review of medical image segmentation from two perspectives:the development of deep network structures and the application of segmentation in ocular imaging.Initially,the article introduces an overview of medical imaging,data processing,and performance evaluation metrics.Subsequently,it analyzes recent developments in U-Net-based network structures.Finally,for the segmentation of ocular medical images,the application of deep learning is reviewed and categorized by the type of ocular tissue.展开更多
Background A medical content-based image retrieval(CBIR)system is designed to retrieve images from large imaging repositories that are visually similar to a user′s query image.CBIR is widely used in evidence-based di...Background A medical content-based image retrieval(CBIR)system is designed to retrieve images from large imaging repositories that are visually similar to a user′s query image.CBIR is widely used in evidence-based diagnosis,teaching,and research.Although the retrieval accuracy has largely improved,there has been limited development toward visualizing important image features that indicate the similarity of retrieved images.Despite the prevalence of 3D volumetric data in medical imaging such as computed tomography(CT),current CBIR systems still rely on 2D cross-sectional views for the visualization of retrieved images.Such 2D visualization requires users to browse through the image stacks to confirm the similarity of the retrieved images and often involves mental reconstruction of 3D information,including the size,shape,and spatial relations of multiple structures.This process is time-consuming and reliant on users'experience.Methods In this study,we proposed an importance-aware 3D volume visualization method.The rendering parameters were automatically optimized to maximize the visibility of important structures that were detected and prioritized in the retrieval process.We then integrated the proposed visualization into a CBIR system,thereby complementing the 2D cross-sectional views for relevance feedback and further analyses.Results Our preliminary results demonstrate that 3D visualization can provide additional information using multimodal positron emission tomography and computed tomography(PETCT)images of a non-small cell lung cancer dataset.展开更多
Deep convolutional neural network (CNN) greatly promotes the automatic segmentation of medical images. However, due to the inherent properties of convolution operations, CNN usually cannot establish long-distance inte...Deep convolutional neural network (CNN) greatly promotes the automatic segmentation of medical images. However, due to the inherent properties of convolution operations, CNN usually cannot establish long-distance interdependence, which limits the segmentation performance. Transformer has been successfully applied to various computer vision, using self-attention mechanism to simulate long-distance interaction, so as to capture global information. However, self-attention lacks spatial location and high-performance computing. In order to solve the above problems, we develop a new medical transformer, which has a multi-scale context fusion function and can be used for medical image segmentation. The proposed model combines convolution operation and attention mechanism to form a u-shaped framework, which can capture both local and global information. First, the traditional converter module is improved to an advanced converter module, which uses post-layer normalization to obtain mild activation values, and uses scaled cosine attention with a moving window to obtain accurate spatial information. Secondly, we also introduce a deep supervision strategy to guide the model to fuse multi-scale feature information. It further enables the proposed model to effectively propagate feature information across layers, Thanks to this, it can achieve better segmentation performance while being more robust and efficient. The proposed model is evaluated on multiple medical image segmentation datasets. Experimental results demonstrate that the proposed model achieves better performance on a challenging dataset (ETIS) compared to existing methods that rely only on convolutional neural networks, transformers, or a combination of both. The mDice and mIou indicators increased by 2.74% and 3.3% respectively.展开更多
The progress in medical imaging technology highlights the importance of image quality for effective diagnosis and treatment.Yet,noise during capture and transmission can compromise image accuracy and reliability,compl...The progress in medical imaging technology highlights the importance of image quality for effective diagnosis and treatment.Yet,noise during capture and transmission can compromise image accuracy and reliability,complicating clinical decisions.The rising interest in diffusion models has led to their exploration of denoising images.We present Be-FOI(Better Fluoro Images),a weakly supervised model that uses cine images to denoise fluoroscopic images,both DR types.Trained through precise noise estimation and simulation,BeFOI employs Markov chains to denoise using only the fluoroscopic image as guidance.Our tests show that BeFOI outperforms other methods,reducing noise and enhancing clar-ity and diagnostic utility,making it an effective post-processing tool for medical images.展开更多
1 Introduction.Chinese medicine has a long and rich history,dating back to the classics of the Qin and Han dynasties and extending to the integration of Chinese and Western medicine in the modern era.The vast amount o...1 Introduction.Chinese medicine has a long and rich history,dating back to the classics of the Qin and Han dynasties and extending to the integration of Chinese and Western medicine in the modern era.The vast amount of literature and scholarly works in this field makes it essential to thoroughly study the history of traditional Chinese medicine(TCM)in order to understand its development path throughout the ages and boost innovation based on tradition.This is why the sages emphasized the importance of“classifying the works into different schools and tracing back to their origins”(辨章学术,考镜源流).展开更多
Background: Rhinoplasty is a complex surgical procedure that requires critical analysis and precise design before surgery, making it a challenging operation for both the surgical team and medical educators. This study...Background: Rhinoplasty is a complex surgical procedure that requires critical analysis and precise design before surgery, making it a challenging operation for both the surgical team and medical educators. This study aimed to evaluate the impact of 3D design involvement on learning curves and to establish a more effective method for rhinoplasty education.Methods: Surgeons who participated in an educational program were divided into two groups. The experimental group was involved in the 3D design before the operation, and the control group was asked to review the rhinoplasty atlas. A self-assessment questionnaire was used to evaluate the learning curve of the eight rhinoplasty procedures for each surgeon, and the overall satisfaction rate data were also collected.Results: The self-assessment scores in both groups showed an increasing trend from the first to the eighth operation. The mean scores of the experimental group were significantly higher than those of the control group at the fifth operation(P=0.01). The satisfaction rate of the experimental group(91.7%) was higher than that of the control group(54.5%).Conclusion: The 3D imaging system can improve the learning curve and satisfaction rate of rhinoplasty education,proving that it is an easy and effective tool for medical education.展开更多
Multimodal medical image fusion has attained immense popularity in recent years due to its robust technology for clinical diagnosis.It fuses multiple images into a single image to improve the quality of images by reta...Multimodal medical image fusion has attained immense popularity in recent years due to its robust technology for clinical diagnosis.It fuses multiple images into a single image to improve the quality of images by retaining significant information and aiding diagnostic practitioners in diagnosing and treating many diseases.However,recent image fusion techniques have encountered several challenges,including fusion artifacts,algorithm complexity,and high computing costs.To solve these problems,this study presents a novel medical image fusion strategy by combining the benefits of pixel significance with edge-preserving processing to achieve the best fusion performance.First,the method employs a cross-bilateral filter(CBF)that utilizes one image to determine the kernel and the other for filtering,and vice versa,by considering both geometric closeness and the gray-level similarities of neighboring pixels of the images without smoothing edges.The outputs of CBF are then subtracted from the original images to obtain detailed images.It further proposes to use edge-preserving processing that combines linear lowpass filtering with a non-linear technique that enables the selection of relevant regions in detailed images while maintaining structural properties.These regions are selected using morphologically processed linear filter residuals to identify the significant regions with high-amplitude edges and adequate size.The outputs of low-pass filtering are fused with meaningfully restored regions to reconstruct the original shape of the edges.In addition,weight computations are performed using these reconstructed images,and these weights are then fused with the original input images to produce a final fusion result by estimating the strength of horizontal and vertical details.Numerous standard quality evaluation metrics with complementary properties are used for comparison with existing,well-known algorithms objectively to validate the fusion results.Experimental results from the proposed research article exhibit superior performance compared to other competing techniques in the case of both qualitative and quantitative evaluation.In addition,the proposed method advocates less computational complexity and execution time while improving diagnostic computing accuracy.Nevertheless,due to the lower complexity of the fusion algorithm,the efficiency of fusion methods is high in practical applications.The results reveal that the proposed method exceeds the latest state-of-the-art methods in terms of providing detailed information,edge contour,and overall contrast.展开更多
Medical imaging plays a key role within modern hospital management systems for diagnostic purposes.Compression methodologies are extensively employed to mitigate storage demands and enhance transmission speed,all whil...Medical imaging plays a key role within modern hospital management systems for diagnostic purposes.Compression methodologies are extensively employed to mitigate storage demands and enhance transmission speed,all while upholding image quality.Moreover,an increasing number of hospitals are embracing cloud computing for patient data storage,necessitating meticulous scrutiny of server security and privacy protocols.Nevertheless,considering the widespread availability of multimedia tools,the preservation of digital data integrity surpasses the significance of compression alone.In response to this concern,we propose a secure storage and transmission solution for compressed medical image sequences,such as ultrasound images,utilizing a motion vector watermarking scheme.The watermark is generated employing an error-correcting code known as Bose-Chaudhuri-Hocquenghem(BCH)and is subsequently embedded into the compressed sequence via block-based motion vectors.In the process of watermark embedding,motion vectors are selected based on their magnitude and phase angle.When embedding watermarks,no specific spatial area,such as a region of interest(ROI),is used in the images.The embedding of watermark bits is dependent on motion vectors.Although reversible watermarking allows the restoration of the original image sequences,we use the irreversible watermarking method.The reason for this is that the use of reversible watermarks may impede the claims of ownership and legal rights.The restoration of original data or images may call into question ownership or other legal claims.The peak signal-to-noise ratio(PSNR)and structural similarity index(SSIM)serve as metrics for evaluating the watermarked image quality.Across all images,the PSNR value exceeds 46 dB,and the SSIM value exceeds 0.92.Experimental results substantiate the efficacy of the proposed technique in preserving data integrity.展开更多
Security during remote transmission has been an important concern for researchers in recent years.In this paper,a hierarchical encryption multi-image encryption scheme for people with different security levels is desi...Security during remote transmission has been an important concern for researchers in recent years.In this paper,a hierarchical encryption multi-image encryption scheme for people with different security levels is designed,and a multiimage encryption(MIE)algorithm with row and column confusion and closed-loop bi-directional diffusion is adopted in the paper.While ensuring secure communication of medical image information,people with different security levels have different levels of decryption keys,and differentiated visual effects can be obtained by using the strong sensitivity of chaotic keys.The highest security level can obtain decrypted images without watermarks,and at the same time,patient information and copyright attribution can be verified by obtaining watermark images.The experimental results show that the scheme is sufficiently secure as an MIE scheme with visualized differences and the encryption and decryption efficiency is significantly improved compared to other works.展开更多
The benefits of regular physical activity are well known.Yet,few studies have examined the effectiveness of integrating physical activity(PA)into curricula within a post-secondary setting.To investigate the incorporat...The benefits of regular physical activity are well known.Yet,few studies have examined the effectiveness of integrating physical activity(PA)into curricula within a post-secondary setting.To investigate the incorporation of PA into medical curriculum,we developed a series of optional exercise-based review sessions designed to reinforce musculoskeletal(MSK)anatomy course material.These synchronous sessions were co-taught by a group fitness instructor and an anatomy instructor.The fitness instructor would lead students through both strength and yoga style exercises,while the anatomy instructor asked questions about relevant anatomical structures related to course material previously covered.After the sessions,participants were asked to evaluate the classes on their self-reported exam preparedness in improving MSK anatomy knowledge,PA levels,and mental wellbeing.Thirty participants completed surveys;a majority agreed that the classes increased understanding of MSK concepts(90.0%)and activity levels(97.7%).Many(70.0%)felt that the classes helped reduce stress.The majority of respondents(90.0%)agreed that the classes contributed to increased feelings of social connectedness.Overall,medical students saw benefit in PA based interventions to supplement MSK course concepts.Along with increasing activity levels and promoting health behaviours,integrating PA into medical curriculum may improve comprehension of learning material,alleviate stress and foster social connectivity among medical students.展开更多
Multimodal medical image fusion can help physicians provide more accurate treatment plans for patients, as unimodal images provide limited valid information. To address the insufficient ability of traditional medical ...Multimodal medical image fusion can help physicians provide more accurate treatment plans for patients, as unimodal images provide limited valid information. To address the insufficient ability of traditional medical image fusion solutions to protect image details and significant information, a new multimodality medical image fusion method(NSST-PAPCNNLatLRR) is proposed in this paper. Firstly, the high and low-frequency sub-band coefficients are obtained by decomposing the source image using NSST. Then, the latent low-rank representation algorithm is used to process the low-frequency sub-band coefficients;An improved PAPCNN algorithm is also proposed for the fusion of high-frequency sub-band coefficients. The improved PAPCNN model was based on the automatic setting of the parameters, and the optimal method was configured for the time decay factor αe. The experimental results show that, in comparison with the five mainstream fusion algorithms, the new algorithm has significantly improved the visual effect over the comparison algorithm,enhanced the ability to characterize important information in images, and further improved the ability to protect the detailed information;the new algorithm has achieved at least four firsts in six objective indexes.展开更多
Mutual information is widely used in medical image registration, because it does not require preprocessing the image. However, the local maximum problem in the registration is insurmountable. We combine mutual informa...Mutual information is widely used in medical image registration, because it does not require preprocessing the image. However, the local maximum problem in the registration is insurmountable. We combine mutual information and gradient information to solve this problem and apply it to the non-rigid deformation image registration. To improve the accuracy, we provide some implemental issues, for example, the Powell searching algorithm, gray interpolation and consideration of outlier points. The experimental results show the accuracy of the method and the feasibility in non-rigid medical image registration.展开更多
文摘Large language models(LLMs),such as ChatGPT developed by OpenAI,represent a significant advancement in artificial intelligence(AI),designed to understand,generate,and interpret human language by analyzing extensive text data.Their potential integration into clinical settings offers a promising avenue that could transform clinical diagnosis and decision-making processes in the future(Thirunavukarasu et al.,2023).This article aims to provide an in-depth analysis of LLMs’current and potential impact on clinical practices.Their ability to generate differential diagnosis lists underscores their potential as invaluable tools in medical practice and education(Hirosawa et al.,2023;Koga et al.,2023).
基金financed by the grant from the Youth Fund for Humanities and Social Sciences Research of the Ministry of Education (No. 19YJCZH040)。
文摘The pancreas is neither part of the five Zang organs(五脏) nor the six Fu organs(六腑).Thus,it has received little attention in Chinese medical literature.In the late 19th century,medical missionaries in China started translating and introducing anatomical and physiological knowledge about the pancreas.As for the word pancreas,an early and influential translation was “sweet meat”(甜肉),proposed by Benjamin Hobson(合信).The translation “sweet meat” is not faithful to the original meaning of “pancreas”,but is a term coined by Hobson based on his personal habits,and the word “sweet” appeared by chance.However,in the decades since the term “sweet meat” became popular,Chinese medicine practitioners,such as Tang Zonghai(唐宗海),reinterpreted it by drawing new medical illustrations for “sweet meat” and giving new connotations to the word “sweet”.This discussion and interpretation of “sweet meat” in modern China,particularly among Chinese medicine professionals,is not only a dissemination and interpretation of the knowledge of “pancreas”,but also a construction of knowledge around the term “sweet meat”.
基金National Natural Science Foundation of China,Grant/Award Numbers:62063004,62350410483Key Research and Development Project of Hainan Province,Grant/Award Number:ZDYF2021SHFZ093Zhejiang Provincial Postdoctoral Science Foundation,Grant/Award Number:ZJ2021028。
文摘In the intricate network environment,the secure transmission of medical images faces challenges such as information leakage and malicious tampering,significantly impacting the accuracy of disease diagnoses by medical professionals.To address this problem,the authors propose a robust feature watermarking algorithm for encrypted medical images based on multi-stage discrete wavelet transform(DWT),Daisy descriptor,and discrete cosine transform(DCT).The algorithm initially encrypts the original medical image through DWT-DCT and Logistic mapping.Subsequently,a 3-stage DWT transformation is applied to the encrypted medical image,with the centre point of the LL3 sub-band within its low-frequency component serving as the sampling point.The Daisy descriptor matrix for this point is then computed.Finally,a DCT transformation is performed on the Daisy descriptor matrix,and the low-frequency portion is processed using the perceptual hashing algorithm to generate a 32-bit binary feature vector for the medical image.This scheme utilises cryptographic knowledge and zero-watermarking technique to embed watermarks without modifying medical images and can extract the watermark from test images without the original image,which meets the basic re-quirements of medical image watermarking.The embedding and extraction of water-marks are accomplished in a mere 0.160 and 0.411s,respectively,with minimal computational overhead.Simulation results demonstrate the robustness of the algorithm against both conventional attacks and geometric attacks,with a notable performance in resisting rotation attacks.
文摘This article proposes a novel fractional heterogeneous neural network by coupling a Rulkov neuron with a Hopfield neural network(FRHNN),utilizing memristors for emulating neural synapses.The study firstly demonstrates the coexistence of multiple firing patterns through phase diagrams,Lyapunov exponents(LEs),and bifurcation diagrams.Secondly,the parameter related firing behaviors are described through two-parameter bifurcation diagrams.Subsequently,local attraction basins reveal multi-stability phenomena related to initial values.Moreover,the proposed model is implemented on a microcomputer-based ARM platform,and the experimental results correspond to the numerical simulations.Finally,the article explores the application of digital watermarking for medical images,illustrating its features of excellent imperceptibility,extensive key space,and robustness against attacks including noise and cropping.
基金funded by Researchers Supporting Program at King Saud University,(RSPD2024R809).
文摘In blood or bone marrow,leukemia is a form of cancer.A person with leukemia has an expansion of white blood cells(WBCs).It primarily affects children and rarely affects adults.Treatment depends on the type of leukemia and the extent to which cancer has established throughout the body.Identifying leukemia in the initial stage is vital to providing timely patient care.Medical image-analysis-related approaches grant safer,quicker,and less costly solutions while ignoring the difficulties of these invasive processes.It can be simple to generalize Computer vision(CV)-based and image-processing techniques and eradicate human error.Many researchers have implemented computer-aided diagnosticmethods andmachine learning(ML)for laboratory image analysis,hopefully overcoming the limitations of late leukemia detection and determining its subgroups.This study establishes a Marine Predators Algorithm with Deep Learning Leukemia Cancer Classification(MPADL-LCC)algorithm onMedical Images.The projectedMPADL-LCC system uses a bilateral filtering(BF)technique to pre-process medical images.The MPADL-LCC system uses Faster SqueezeNet withMarine Predators Algorithm(MPA)as a hyperparameter optimizer for feature extraction.Lastly,the denoising autoencoder(DAE)methodology can be executed to accurately detect and classify leukemia cancer.The hyperparameter tuning process using MPA helps enhance leukemia cancer classification performance.Simulation results are compared with other recent approaches concerning various measurements and the MPADL-LCC algorithm exhibits the best results over other recent approaches.
基金supported by the National Key R&D Program of China(2018AAA0102100)the National Natural Science Foundation of China(No.62376287)+3 种基金the International Science and Technology Innovation Joint Base of Machine Vision and Medical Image Processing in Hunan Province(2021CB1013)the Key Research and Development Program of Hunan Province(2022SK2054)the Natural Science Foundation of Hunan Province(No.2022JJ30762,2023JJ70016)the 111 Project under Grant(No.B18059).
文摘Automatic segmentation of medical images provides a reliable scientific basis for disease diagnosis and analysis.Notably,most existing methods that combine the strengths of convolutional neural networks(CNNs)and Transformers have made significant progress.However,there are some limitations in the current integration of CNN and Transformer technology in two key aspects.Firstly,most methods either overlook or fail to fully incorporate the complementary nature between local and global features.Secondly,the significance of integrating the multiscale encoder features from the dual-branch network to enhance the decoding features is often disregarded in methods that combine CNN and Transformer.To address this issue,we present a groundbreaking dual-branch cross-attention fusion network(DCFNet),which efficiently combines the power of Swin Transformer and CNN to generate complementary global and local features.We then designed the Feature Cross-Fusion(FCF)module to efficiently fuse local and global features.In the FCF,the utilization of the Channel-wise Cross-fusion Transformer(CCT)serves the purpose of aggregatingmulti-scale features,and the Feature FusionModule(FFM)is employed to effectively aggregate dual-branch prominent feature regions from the spatial perspective.Furthermore,within the decoding phase of the dual-branch network,our proposed Channel Attention Block(CAB)aims to emphasize the significance of the channel features between the up-sampled features and the features generated by the FCFmodule to enhance the details of the decoding.Experimental results demonstrate that DCFNet exhibits enhanced accuracy in segmentation performance.Compared to other state-of-the-art(SOTA)methods,our segmentation framework exhibits a superior level of competitiveness.DCFNet’s accurate segmentation of medical images can greatly assist medical professionals in making crucial diagnoses of lesion areas in advance.
文摘The Internet of Multimedia Things(IoMT)refers to a network of interconnected multimedia devices that communicate with each other over the Internet.Recently,smart healthcare has emerged as a significant application of the IoMT,particularly in the context of knowledge‐based learning systems.Smart healthcare systems leverage knowledge‐based learning to become more context‐aware,adaptable,and auditable while maintain-ing the ability to learn from historical data.In smart healthcare systems,devices capture images,such as X‐rays,Magnetic Resonance Imaging.The security and integrity of these images are crucial for the databases used in knowledge‐based learning systems to foster structured decision‐making and enhance the learning abilities of AI.Moreover,in knowledge‐driven systems,the storage and transmission of HD medical images exert a burden on the limited bandwidth of the communication channel,leading to data trans-mission delays.To address the security and latency concerns,this paper presents a lightweight medical image encryption scheme utilising bit‐plane decomposition and chaos theory.The results of the experiment yield entropy,energy,and correlation values of 7.999,0.0156,and 0.0001,respectively.This validates the effectiveness of the encryption system proposed in this paper,which offers high‐quality encryption,a large key space,key sensitivity,and resistance to statistical attacks.
基金Major Program of National Natural Science Foundation of China(NSFC12292980,NSFC12292984)National Key R&D Program of China(2023YFA1009000,2023YFA1009004,2020YFA0712203,2020YFA0712201)+2 种基金Major Program of National Natural Science Foundation of China(NSFC12031016)Beijing Natural Science Foundation(BNSFZ210003)Department of Science,Technology and Information of the Ministry of Education(8091B042240).
文摘Gliomas have the highest mortality rate of all brain tumors.Correctly classifying the glioma risk period can help doctors make reasonable treatment plans and improve patients’survival rates.This paper proposes a hierarchical multi-scale attention feature fusion medical image classification network(HMAC-Net),which effectively combines global features and local features.The network framework consists of three parallel layers:The global feature extraction layer,the local feature extraction layer,and the multi-scale feature fusion layer.A linear sparse attention mechanism is designed in the global feature extraction layer to reduce information redundancy.In the local feature extraction layer,a bilateral local attention mechanism is introduced to improve the extraction of relevant information between adjacent slices.In the multi-scale feature fusion layer,a channel fusion block combining convolutional attention mechanism and residual inverse multi-layer perceptron is proposed to prevent gradient disappearance and network degradation and improve feature representation capability.The double-branch iterative multi-scale classification block is used to improve the classification performance.On the brain glioma risk grading dataset,the results of the ablation experiment and comparison experiment show that the proposed HMAC-Net has the best performance in both qualitative analysis of heat maps and quantitative analysis of evaluation indicators.On the dataset of skin cancer classification,the generalization experiment results show that the proposed HMAC-Net has a good generalization effect.
文摘Deep learning has been extensively applied to medical image segmentation,resulting in significant advancements in the field of deep neural networks for medical image segmentation since the notable success of U Net in 2015.However,the application of deep learning models to ocular medical image segmentation poses unique challenges,especially compared to other body parts,due to the complexity,small size,and blurriness of such images,coupled with the scarcity of data.This article aims to provide a comprehensive review of medical image segmentation from two perspectives:the development of deep network structures and the application of segmentation in ocular imaging.Initially,the article introduces an overview of medical imaging,data processing,and performance evaluation metrics.Subsequently,it analyzes recent developments in U-Net-based network structures.Finally,for the segmentation of ocular medical images,the application of deep learning is reviewed and categorized by the type of ocular tissue.
文摘Background A medical content-based image retrieval(CBIR)system is designed to retrieve images from large imaging repositories that are visually similar to a user′s query image.CBIR is widely used in evidence-based diagnosis,teaching,and research.Although the retrieval accuracy has largely improved,there has been limited development toward visualizing important image features that indicate the similarity of retrieved images.Despite the prevalence of 3D volumetric data in medical imaging such as computed tomography(CT),current CBIR systems still rely on 2D cross-sectional views for the visualization of retrieved images.Such 2D visualization requires users to browse through the image stacks to confirm the similarity of the retrieved images and often involves mental reconstruction of 3D information,including the size,shape,and spatial relations of multiple structures.This process is time-consuming and reliant on users'experience.Methods In this study,we proposed an importance-aware 3D volume visualization method.The rendering parameters were automatically optimized to maximize the visibility of important structures that were detected and prioritized in the retrieval process.We then integrated the proposed visualization into a CBIR system,thereby complementing the 2D cross-sectional views for relevance feedback and further analyses.Results Our preliminary results demonstrate that 3D visualization can provide additional information using multimodal positron emission tomography and computed tomography(PETCT)images of a non-small cell lung cancer dataset.
文摘Deep convolutional neural network (CNN) greatly promotes the automatic segmentation of medical images. However, due to the inherent properties of convolution operations, CNN usually cannot establish long-distance interdependence, which limits the segmentation performance. Transformer has been successfully applied to various computer vision, using self-attention mechanism to simulate long-distance interaction, so as to capture global information. However, self-attention lacks spatial location and high-performance computing. In order to solve the above problems, we develop a new medical transformer, which has a multi-scale context fusion function and can be used for medical image segmentation. The proposed model combines convolution operation and attention mechanism to form a u-shaped framework, which can capture both local and global information. First, the traditional converter module is improved to an advanced converter module, which uses post-layer normalization to obtain mild activation values, and uses scaled cosine attention with a moving window to obtain accurate spatial information. Secondly, we also introduce a deep supervision strategy to guide the model to fuse multi-scale feature information. It further enables the proposed model to effectively propagate feature information across layers, Thanks to this, it can achieve better segmentation performance while being more robust and efficient. The proposed model is evaluated on multiple medical image segmentation datasets. Experimental results demonstrate that the proposed model achieves better performance on a challenging dataset (ETIS) compared to existing methods that rely only on convolutional neural networks, transformers, or a combination of both. The mDice and mIou indicators increased by 2.74% and 3.3% respectively.
文摘The progress in medical imaging technology highlights the importance of image quality for effective diagnosis and treatment.Yet,noise during capture and transmission can compromise image accuracy and reliability,complicating clinical decisions.The rising interest in diffusion models has led to their exploration of denoising images.We present Be-FOI(Better Fluoro Images),a weakly supervised model that uses cine images to denoise fluoroscopic images,both DR types.Trained through precise noise estimation and simulation,BeFOI employs Markov chains to denoise using only the fluoroscopic image as guidance.Our tests show that BeFOI outperforms other methods,reducing noise and enhancing clar-ity and diagnostic utility,making it an effective post-processing tool for medical images.
基金financed by the grant from Beijing Social Science(No. 18LSB002)。
文摘1 Introduction.Chinese medicine has a long and rich history,dating back to the classics of the Qin and Han dynasties and extending to the integration of Chinese and Western medicine in the modern era.The vast amount of literature and scholarly works in this field makes it essential to thoroughly study the history of traditional Chinese medicine(TCM)in order to understand its development path throughout the ages and boost innovation based on tradition.This is why the sages emphasized the importance of“classifying the works into different schools and tracing back to their origins”(辨章学术,考镜源流).
文摘Background: Rhinoplasty is a complex surgical procedure that requires critical analysis and precise design before surgery, making it a challenging operation for both the surgical team and medical educators. This study aimed to evaluate the impact of 3D design involvement on learning curves and to establish a more effective method for rhinoplasty education.Methods: Surgeons who participated in an educational program were divided into two groups. The experimental group was involved in the 3D design before the operation, and the control group was asked to review the rhinoplasty atlas. A self-assessment questionnaire was used to evaluate the learning curve of the eight rhinoplasty procedures for each surgeon, and the overall satisfaction rate data were also collected.Results: The self-assessment scores in both groups showed an increasing trend from the first to the eighth operation. The mean scores of the experimental group were significantly higher than those of the control group at the fifth operation(P=0.01). The satisfaction rate of the experimental group(91.7%) was higher than that of the control group(54.5%).Conclusion: The 3D imaging system can improve the learning curve and satisfaction rate of rhinoplasty education,proving that it is an easy and effective tool for medical education.
文摘Multimodal medical image fusion has attained immense popularity in recent years due to its robust technology for clinical diagnosis.It fuses multiple images into a single image to improve the quality of images by retaining significant information and aiding diagnostic practitioners in diagnosing and treating many diseases.However,recent image fusion techniques have encountered several challenges,including fusion artifacts,algorithm complexity,and high computing costs.To solve these problems,this study presents a novel medical image fusion strategy by combining the benefits of pixel significance with edge-preserving processing to achieve the best fusion performance.First,the method employs a cross-bilateral filter(CBF)that utilizes one image to determine the kernel and the other for filtering,and vice versa,by considering both geometric closeness and the gray-level similarities of neighboring pixels of the images without smoothing edges.The outputs of CBF are then subtracted from the original images to obtain detailed images.It further proposes to use edge-preserving processing that combines linear lowpass filtering with a non-linear technique that enables the selection of relevant regions in detailed images while maintaining structural properties.These regions are selected using morphologically processed linear filter residuals to identify the significant regions with high-amplitude edges and adequate size.The outputs of low-pass filtering are fused with meaningfully restored regions to reconstruct the original shape of the edges.In addition,weight computations are performed using these reconstructed images,and these weights are then fused with the original input images to produce a final fusion result by estimating the strength of horizontal and vertical details.Numerous standard quality evaluation metrics with complementary properties are used for comparison with existing,well-known algorithms objectively to validate the fusion results.Experimental results from the proposed research article exhibit superior performance compared to other competing techniques in the case of both qualitative and quantitative evaluation.In addition,the proposed method advocates less computational complexity and execution time while improving diagnostic computing accuracy.Nevertheless,due to the lower complexity of the fusion algorithm,the efficiency of fusion methods is high in practical applications.The results reveal that the proposed method exceeds the latest state-of-the-art methods in terms of providing detailed information,edge contour,and overall contrast.
基金supported by the Yayasan Universiti Teknologi PETRONAS Grants,YUTP-PRG(015PBC-027)YUTP-FRG(015LC0-311),Hilmi Hasan,www.utp.edu.my.
文摘Medical imaging plays a key role within modern hospital management systems for diagnostic purposes.Compression methodologies are extensively employed to mitigate storage demands and enhance transmission speed,all while upholding image quality.Moreover,an increasing number of hospitals are embracing cloud computing for patient data storage,necessitating meticulous scrutiny of server security and privacy protocols.Nevertheless,considering the widespread availability of multimedia tools,the preservation of digital data integrity surpasses the significance of compression alone.In response to this concern,we propose a secure storage and transmission solution for compressed medical image sequences,such as ultrasound images,utilizing a motion vector watermarking scheme.The watermark is generated employing an error-correcting code known as Bose-Chaudhuri-Hocquenghem(BCH)and is subsequently embedded into the compressed sequence via block-based motion vectors.In the process of watermark embedding,motion vectors are selected based on their magnitude and phase angle.When embedding watermarks,no specific spatial area,such as a region of interest(ROI),is used in the images.The embedding of watermark bits is dependent on motion vectors.Although reversible watermarking allows the restoration of the original image sequences,we use the irreversible watermarking method.The reason for this is that the use of reversible watermarks may impede the claims of ownership and legal rights.The restoration of original data or images may call into question ownership or other legal claims.The peak signal-to-noise ratio(PSNR)and structural similarity index(SSIM)serve as metrics for evaluating the watermarked image quality.Across all images,the PSNR value exceeds 46 dB,and the SSIM value exceeds 0.92.Experimental results substantiate the efficacy of the proposed technique in preserving data integrity.
基金Project supported by the National Natural Science Foundation of China(Grant No.62061014)the Natural Science Foundation of Liaoning province of China(Grant No.2020-MS-274).
文摘Security during remote transmission has been an important concern for researchers in recent years.In this paper,a hierarchical encryption multi-image encryption scheme for people with different security levels is designed,and a multiimage encryption(MIE)algorithm with row and column confusion and closed-loop bi-directional diffusion is adopted in the paper.While ensuring secure communication of medical image information,people with different security levels have different levels of decryption keys,and differentiated visual effects can be obtained by using the strong sensitivity of chaotic keys.The highest security level can obtain decrypted images without watermarks,and at the same time,patient information and copyright attribution can be verified by obtaining watermark images.The experimental results show that the scheme is sufficiently secure as an MIE scheme with visualized differences and the encryption and decryption efficiency is significantly improved compared to other works.
文摘The benefits of regular physical activity are well known.Yet,few studies have examined the effectiveness of integrating physical activity(PA)into curricula within a post-secondary setting.To investigate the incorporation of PA into medical curriculum,we developed a series of optional exercise-based review sessions designed to reinforce musculoskeletal(MSK)anatomy course material.These synchronous sessions were co-taught by a group fitness instructor and an anatomy instructor.The fitness instructor would lead students through both strength and yoga style exercises,while the anatomy instructor asked questions about relevant anatomical structures related to course material previously covered.After the sessions,participants were asked to evaluate the classes on their self-reported exam preparedness in improving MSK anatomy knowledge,PA levels,and mental wellbeing.Thirty participants completed surveys;a majority agreed that the classes increased understanding of MSK concepts(90.0%)and activity levels(97.7%).Many(70.0%)felt that the classes helped reduce stress.The majority of respondents(90.0%)agreed that the classes contributed to increased feelings of social connectedness.Overall,medical students saw benefit in PA based interventions to supplement MSK course concepts.Along with increasing activity levels and promoting health behaviours,integrating PA into medical curriculum may improve comprehension of learning material,alleviate stress and foster social connectivity among medical students.
基金funded by the National Natural Science Foundation of China,grant number 61302188.
文摘Multimodal medical image fusion can help physicians provide more accurate treatment plans for patients, as unimodal images provide limited valid information. To address the insufficient ability of traditional medical image fusion solutions to protect image details and significant information, a new multimodality medical image fusion method(NSST-PAPCNNLatLRR) is proposed in this paper. Firstly, the high and low-frequency sub-band coefficients are obtained by decomposing the source image using NSST. Then, the latent low-rank representation algorithm is used to process the low-frequency sub-band coefficients;An improved PAPCNN algorithm is also proposed for the fusion of high-frequency sub-band coefficients. The improved PAPCNN model was based on the automatic setting of the parameters, and the optimal method was configured for the time decay factor αe. The experimental results show that, in comparison with the five mainstream fusion algorithms, the new algorithm has significantly improved the visual effect over the comparison algorithm,enhanced the ability to characterize important information in images, and further improved the ability to protect the detailed information;the new algorithm has achieved at least four firsts in six objective indexes.
文摘Mutual information is widely used in medical image registration, because it does not require preprocessing the image. However, the local maximum problem in the registration is insurmountable. We combine mutual information and gradient information to solve this problem and apply it to the non-rigid deformation image registration. To improve the accuracy, we provide some implemental issues, for example, the Powell searching algorithm, gray interpolation and consideration of outlier points. The experimental results show the accuracy of the method and the feasibility in non-rigid medical image registration.