Title: Integrating Consistent Individualized Carbohydrate-Controlled Anti- Inflammatory Nutritional Plan (C-ICAN) in the Management of Prader-Willi Syndrome: A Case Report. Prader–Willi syndrome (PWS) is a rare genet...Title: Integrating Consistent Individualized Carbohydrate-Controlled Anti- Inflammatory Nutritional Plan (C-ICAN) in the Management of Prader-Willi Syndrome: A Case Report. Prader–Willi syndrome (PWS) is a rare genetic disorder caused by a loss of function of specific genes on chromosome 15. Patients with this disease present unique challenges in management, particularly regarding obesity and nutritional regulation as the disease symptoms change depending on the age of the patient and the phase of the disease. These challenges pose critical stressors to caregivers and their families. We present a case report of a 5-year-old Caucasian male diagnosed with PWS, exhibiting failure to thrive and uncontrolled weight gain. His caregiver was his elderly grandmother who, by her own admission, was ill-equipped to deal with the patient’s physical symptoms and his behavior in response to dietary restrictions. Through a multidisciplinary approach involving medical nutrition therapy (MNT) involving the implementation of a Consistent Individualized Carbohydrate-Controlled Anti-Inflammatory Nutritional plan (C-ICAN), growth hormone supplementation, and behavioral interventions patient markedly improved physically and emotionally.展开更多
Objective To investigate the relationship between glycosylated hemoglobin A1 c （HbA1 c） and blood glucose levels of eight different points throughout the day in well-glycemic-controlled medical nutrition therapy （...Objective To investigate the relationship between glycosylated hemoglobin A1 c （HbA1 c） and blood glucose levels of eight different points throughout the day in well-glycemic-controlled medical nutrition therapy （MNT） alone type 2 diabetic pafients. Methods Data were collected as＂ capillary blood glucose value of eight different sample points among sixteen observing days in thirty MNT alone type 2 diabetic patients. The correlation between HbAI c and capillary blood glucose value was evaluated by Pearson＇s correlation method. Results The r-values between HbA1c and capillary blood glucose of 3：00, 6：00, and bedtime （22：00-23：00） were 0. 81,0. 79, and 0. 78, respectively（P 〈0. 001 ）. The best correlation was found between the mean value of 8- point blood glucose value throughout the day and HbA1c （ r=0. 84, P 〈0. 001 ）. Conclustion Fasting blood glucose and postabsorptive blood glucose have better correlations with HbAlc compared with other points in this group of well-glycemic-controlled MNT alone type 2 diabetic patients.展开更多
目的探讨医学营养疗法(MNT)联合运动锻炼治疗糖尿病高血压患者的临床疗效及对血清基质金属蛋白酶2(MMP-2)、组织抑制因子1(TIMP-1)的影响。方法选择2017年3月至2018年1月收治的糖尿病高血压患者100例,按照随机数字表法分为对照组(n=50)...目的探讨医学营养疗法(MNT)联合运动锻炼治疗糖尿病高血压患者的临床疗效及对血清基质金属蛋白酶2(MMP-2)、组织抑制因子1(TIMP-1)的影响。方法选择2017年3月至2018年1月收治的糖尿病高血压患者100例,按照随机数字表法分为对照组(n=50)和观察组(n=50)。对照组采用常规药物治疗,观察组在对照组基础上采用MNT联合运动锻炼治疗。比较两组患者的临床疗效、治疗前、后血压、血糖、MMP-2和TIMP-1水平。结果观察组治疗总有效率高于对照组,差异具有统计学意义(P<0.05)。治疗后,两组患者SDP、DBP、FBG及2 h PBG水平均显著低于治疗前,且观察组均低于对照组,差异具有统计学意义(P<0.05)。治疗后,两组患者MMP-2水平均升高,TIMP-1水平均降低,且观察组均优于对照组,差异具有统计学意义(P<0.05)。结论在糖尿病高血压患者治疗中,在常规药物治疗基础上采用MNT联合运动锻炼能显著提高临床疗效,控制患者血压、血糖水平,改善MMP-2和TIMP-1水平,值得推广应用。展开更多
文摘Title: Integrating Consistent Individualized Carbohydrate-Controlled Anti- Inflammatory Nutritional Plan (C-ICAN) in the Management of Prader-Willi Syndrome: A Case Report. Prader–Willi syndrome (PWS) is a rare genetic disorder caused by a loss of function of specific genes on chromosome 15. Patients with this disease present unique challenges in management, particularly regarding obesity and nutritional regulation as the disease symptoms change depending on the age of the patient and the phase of the disease. These challenges pose critical stressors to caregivers and their families. We present a case report of a 5-year-old Caucasian male diagnosed with PWS, exhibiting failure to thrive and uncontrolled weight gain. His caregiver was his elderly grandmother who, by her own admission, was ill-equipped to deal with the patient’s physical symptoms and his behavior in response to dietary restrictions. Through a multidisciplinary approach involving medical nutrition therapy (MNT) involving the implementation of a Consistent Individualized Carbohydrate-Controlled Anti-Inflammatory Nutritional plan (C-ICAN), growth hormone supplementation, and behavioral interventions patient markedly improved physically and emotionally.
文摘Objective To investigate the relationship between glycosylated hemoglobin A1 c （HbA1 c） and blood glucose levels of eight different points throughout the day in well-glycemic-controlled medical nutrition therapy （MNT） alone type 2 diabetic pafients. Methods Data were collected as＂ capillary blood glucose value of eight different sample points among sixteen observing days in thirty MNT alone type 2 diabetic patients. The correlation between HbAI c and capillary blood glucose value was evaluated by Pearson＇s correlation method. Results The r-values between HbA1c and capillary blood glucose of 3：00, 6：00, and bedtime （22：00-23：00） were 0. 81,0. 79, and 0. 78, respectively（P 〈0. 001 ）. The best correlation was found between the mean value of 8- point blood glucose value throughout the day and HbA1c （ r=0. 84, P 〈0. 001 ）. Conclustion Fasting blood glucose and postabsorptive blood glucose have better correlations with HbAlc compared with other points in this group of well-glycemic-controlled MNT alone type 2 diabetic patients.
文摘目的探讨医学营养疗法(MNT)联合运动锻炼治疗糖尿病高血压患者的临床疗效及对血清基质金属蛋白酶2(MMP-2)、组织抑制因子1(TIMP-1)的影响。方法选择2017年3月至2018年1月收治的糖尿病高血压患者100例,按照随机数字表法分为对照组(n=50)和观察组(n=50)。对照组采用常规药物治疗,观察组在对照组基础上采用MNT联合运动锻炼治疗。比较两组患者的临床疗效、治疗前、后血压、血糖、MMP-2和TIMP-1水平。结果观察组治疗总有效率高于对照组,差异具有统计学意义(P<0.05)。治疗后,两组患者SDP、DBP、FBG及2 h PBG水平均显著低于治疗前,且观察组均低于对照组,差异具有统计学意义(P<0.05)。治疗后,两组患者MMP-2水平均升高,TIMP-1水平均降低,且观察组均优于对照组,差异具有统计学意义(P<0.05)。结论在糖尿病高血压患者治疗中,在常规药物治疗基础上采用MNT联合运动锻炼能显著提高临床疗效,控制患者血压、血糖水平,改善MMP-2和TIMP-1水平,值得推广应用。
