Objective:To analyze the risk factors of neonatal medical adhesive-related skin injury and put forward targeted preventive measures,so as to provide reference for the care and prevention of neonatal medical adhesive-r...Objective:To analyze the risk factors of neonatal medical adhesive-related skin injury and put forward targeted preventive measures,so as to provide reference for the care and prevention of neonatal medical adhesive-related skin injuries.Methods:Using the convenience sampling method,262 neonates admitted to the neonatal intensive care unit(NICU)of a tertiary general hospital in Wenzhou from April 2021 to May 2022 were selected as the study subjects.The incidence of medical adhesive-related skin injuries in these neonates was retrospectively analyzed.Results:Among the 262 children,43 cases had skin injuries,with an incidence rate of 16.4%.Single factor analysis showed that the occurrence of medical adhesive-related skin injury was related to gestational age,weight,electrocardiogram(ECG)monitoring,venous access,ambient temperature,and mechanical ventilation(P<0.05).Multivariate logistic regression showed that gestational age,ECG monitoring,and ambient temperature were independent risk factors of medical adhesive-related skin injury(OR values were 0.700,0.431,and 6.365,respectively).Conclusion:The high incidence of neonatal medical adhesive-related skin injury may be caused by one or more factors.Clinical measures should be taken,such as selecting the appropriate type of adhesive according to gestational age and using skin-protecting membrane,minimizing ECG monitoring,etc.,to prevent the occurrence of neonatal medical adhesive-related skin injury.展开更多
AIM:To evaluate the use of medical adhesive spray in endoscopic submucosal dissection (ESD). METHODS:Patients who underwent ESD between January 2009 and June 2012 (n = 173) were enrolled in the prospective randomized ...AIM:To evaluate the use of medical adhesive spray in endoscopic submucosal dissection (ESD). METHODS:Patients who underwent ESD between January 2009 and June 2012 (n = 173) were enrolled in the prospective randomized study. Two patients undergoing surgery due to severe intraoperative hemorrhage and failed hemostasis were excluded, and the remaining 171 patients were randomly divided into two groups:group A (medical adhesive group, n = 89) and group B (control group, n = 82). In group A, a medical adhesive spray was evenly applied after routine electrocoagulation and hemostasis using hemostatic clip after ESD. Patients in group B only treated with routine wound management. Intraoperative and postoperative data were collected and compared. RESULTS:In all 171 patients, ESD was successfully completed. There was no significant difference in the average treatment time between groups A and B (59.4 min vs 55.0 min, respectively). The average length of hospital stay was significantly different between group A and B (8.89 d vs 9.90 d, respectively). The incidence of intraoperative perforation was 10.1% in group A and 9.8% in group B, and was not significantly different between the two groups. In all cases, perforations were successfully managed endoscopically and with conservative treatment. The incidence of postoperative delayed bleeding in group A was significantly lower than that in group B (0.00% vs 4.88%, respectively). CONCLUSION:ESD is an effective minimally invasive treatment for gastrointestinal precancerous lesions or early-stage gastrointestinal cancer. Medical adhesive spray is effective in preventing delayed bleeding after ESD, and can thus reduce the average length of hospital stay.展开更多
Copolymerization as an efficient strategy can provide an opportunity to create new closed-loop recyclable polymeric materials with tailored properties that are generally inaccessible to the individual homopolymers.In ...Copolymerization as an efficient strategy can provide an opportunity to create new closed-loop recyclable polymeric materials with tailored properties that are generally inaccessible to the individual homopolymers.In this contribution,the bulk ring-opening copolymerization of bio-renewable-caprolactone and trans-hexahydro-(4,5)-benzofuranone was achieved to produce closed-loop recyclable copolyesters by using an organobase/urea binary catalyst at room temperature.The obtained copolyesters exhibited composition-dependent thermal properties.Remarkably,the obtained copolyesters were able to depolymerize back to recover the corresponding monomers under mild conditions.展开更多
目的:对肿瘤病人发生医用粘胶相关性皮肤损伤(MARSI)的危险因素进行范围综述,为临床预防MARSI提供参考。方法:检索the Cochrane Library、PubMed、Web of Science、EMbase、万方数据库、中国知网、维普数据库、中国生物医学文献数据库...目的:对肿瘤病人发生医用粘胶相关性皮肤损伤(MARSI)的危险因素进行范围综述,为临床预防MARSI提供参考。方法:检索the Cochrane Library、PubMed、Web of Science、EMbase、万方数据库、中国知网、维普数据库、中国生物医学文献数据库中肿瘤病人MARSI危险因素的相关文献,检索时限从建库至2023年3月31日。由2名研究者进行筛选文献、提取资料,并报告研究结果。结果:共纳入9篇文献,涉及2673例肿瘤病人,共13个危险因素。包括病人因素如年龄、过敏史、体质指数、皮肤潮湿、MARSI史;医源性因素如经外周静脉置入中心静脉导管(PICC)维护方法、穿刺部位、穿刺次数、化疗用药;疾病因素如糖尿病、生殖系统肿瘤、血液系统肿瘤以及民族等社会人口学因素均与肿瘤病人发生MARSI有关。结论:现有研究证据表明,肿瘤病人发生MARSI的危险因素较多,但纳入研究类型有限,未来须更多高质量研究进行更深层次的验证。展开更多
基金the Basic Medical and Health Technology Project of Wenzhou Science and Technology Bureau(Y20190308).
文摘Objective:To analyze the risk factors of neonatal medical adhesive-related skin injury and put forward targeted preventive measures,so as to provide reference for the care and prevention of neonatal medical adhesive-related skin injuries.Methods:Using the convenience sampling method,262 neonates admitted to the neonatal intensive care unit(NICU)of a tertiary general hospital in Wenzhou from April 2021 to May 2022 were selected as the study subjects.The incidence of medical adhesive-related skin injuries in these neonates was retrospectively analyzed.Results:Among the 262 children,43 cases had skin injuries,with an incidence rate of 16.4%.Single factor analysis showed that the occurrence of medical adhesive-related skin injury was related to gestational age,weight,electrocardiogram(ECG)monitoring,venous access,ambient temperature,and mechanical ventilation(P<0.05).Multivariate logistic regression showed that gestational age,ECG monitoring,and ambient temperature were independent risk factors of medical adhesive-related skin injury(OR values were 0.700,0.431,and 6.365,respectively).Conclusion:The high incidence of neonatal medical adhesive-related skin injury may be caused by one or more factors.Clinical measures should be taken,such as selecting the appropriate type of adhesive according to gestational age and using skin-protecting membrane,minimizing ECG monitoring,etc.,to prevent the occurrence of neonatal medical adhesive-related skin injury.
基金Supported by Shanghai Key Laboratory of Pediatric Digestion and Nutrition,No.11DZ2260500 and NO.2010009
文摘AIM:To evaluate the use of medical adhesive spray in endoscopic submucosal dissection (ESD). METHODS:Patients who underwent ESD between January 2009 and June 2012 (n = 173) were enrolled in the prospective randomized study. Two patients undergoing surgery due to severe intraoperative hemorrhage and failed hemostasis were excluded, and the remaining 171 patients were randomly divided into two groups:group A (medical adhesive group, n = 89) and group B (control group, n = 82). In group A, a medical adhesive spray was evenly applied after routine electrocoagulation and hemostasis using hemostatic clip after ESD. Patients in group B only treated with routine wound management. Intraoperative and postoperative data were collected and compared. RESULTS:In all 171 patients, ESD was successfully completed. There was no significant difference in the average treatment time between groups A and B (59.4 min vs 55.0 min, respectively). The average length of hospital stay was significantly different between group A and B (8.89 d vs 9.90 d, respectively). The incidence of intraoperative perforation was 10.1% in group A and 9.8% in group B, and was not significantly different between the two groups. In all cases, perforations were successfully managed endoscopically and with conservative treatment. The incidence of postoperative delayed bleeding in group A was significantly lower than that in group B (0.00% vs 4.88%, respectively). CONCLUSION:ESD is an effective minimally invasive treatment for gastrointestinal precancerous lesions or early-stage gastrointestinal cancer. Medical adhesive spray is effective in preventing delayed bleeding after ESD, and can thus reduce the average length of hospital stay.
基金support by National Natural Science Foundation of China(Nos.52322304,22075160 and 22031005)Taishan Scholar Foundation of Shandong Province(No.tsqn202103078).
文摘Copolymerization as an efficient strategy can provide an opportunity to create new closed-loop recyclable polymeric materials with tailored properties that are generally inaccessible to the individual homopolymers.In this contribution,the bulk ring-opening copolymerization of bio-renewable-caprolactone and trans-hexahydro-(4,5)-benzofuranone was achieved to produce closed-loop recyclable copolyesters by using an organobase/urea binary catalyst at room temperature.The obtained copolyesters exhibited composition-dependent thermal properties.Remarkably,the obtained copolyesters were able to depolymerize back to recover the corresponding monomers under mild conditions.
文摘目的:对肿瘤病人发生医用粘胶相关性皮肤损伤(MARSI)的危险因素进行范围综述,为临床预防MARSI提供参考。方法:检索the Cochrane Library、PubMed、Web of Science、EMbase、万方数据库、中国知网、维普数据库、中国生物医学文献数据库中肿瘤病人MARSI危险因素的相关文献,检索时限从建库至2023年3月31日。由2名研究者进行筛选文献、提取资料,并报告研究结果。结果:共纳入9篇文献,涉及2673例肿瘤病人,共13个危险因素。包括病人因素如年龄、过敏史、体质指数、皮肤潮湿、MARSI史;医源性因素如经外周静脉置入中心静脉导管(PICC)维护方法、穿刺部位、穿刺次数、化疗用药;疾病因素如糖尿病、生殖系统肿瘤、血液系统肿瘤以及民族等社会人口学因素均与肿瘤病人发生MARSI有关。结论:现有研究证据表明,肿瘤病人发生MARSI的危险因素较多,但纳入研究类型有限,未来须更多高质量研究进行更深层次的验证。
