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Consideration of the influence of supports in modeling the electromagnetic fields of 25 kV traction networks under emergency conditions
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作者 Konstantin Suslov Andrey Kryukov +1 位作者 Ekaterina Voronina Pavel Ilyushin 《Global Energy Interconnection》 EI CSCD 2024年第4期528-540,共13页
Single-phase 25 kV traction networks of electrified alternating current(AC)railways create electromagnetic fields(EMFs)with significant levels of intensity.The most intense magnetic fields occur when short circuits ex... Single-phase 25 kV traction networks of electrified alternating current(AC)railways create electromagnetic fields(EMFs)with significant levels of intensity.The most intense magnetic fields occur when short circuits exist between the contact wire and rails or ground.Despite the short duration of exposure,they can adversely affect electronic devices and induce significant voltages in adjacent power lines,which is dangerous for operating personnel.Although numerous investigations have focused on modeling the EMF of traction networks and power lines,the challenge of determining the three-dimensional electromagnetic fields near metal supports during the flow of a short-circuit current through them is yet to be resolved.In this case,the field has a complex spatial structure that significantly complicates the calculations of intensities.This study proposes a methodology,algorithms,software,and digital models for determining the EMF in the described emergency scenarios.During the modeling process,the objects being studied were represented by segments of thin wires to analyze the distribution of the electric charge and calculate the intensities of the electric and magnetic fields.This approach was implemented in the Fazonord software,and the modeling results show a substantial increase in EMF levels close to the support,with a noticeable decrease in the levels as the distance from it increases.The procedure implemented in the commercial software Fazonord is universal and can be used to determine electromagnetic fields at any electrical power facility that includes live parts of limited length.Based on the proposed procedure,the EMF near the supports of overhead power lines and traction networks of various designs could be determined,the EMF levels at substations can be calculated,and the influence of metal structures located near traction networks,such as pedestrian crossings at railway stations,can be considered. 展开更多
关键词 Power supply systems AC railways Emergency conditions electromagnetic fields near supports MODELING electromagnetic safety
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An internal ballistic model of electromagnetic railgun based on PFN coupled with multi-physical field and experimental validation
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作者 Benfeng Gu Haiyuan Li Baoming Li 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第2期254-261,共8页
To accelerate the practicality of electromagnetic railguns,it is necessary to use a combination of threedimensional numerical simulation and experiments to study the mechanism of bore damage.In this paper,a three-dime... To accelerate the practicality of electromagnetic railguns,it is necessary to use a combination of threedimensional numerical simulation and experiments to study the mechanism of bore damage.In this paper,a three-dimensional numerical model of the augmented railgun with four parallel unconventional rails is introduced to simulate the internal ballistic process and realize the multi-physics field coupling calculation of the rail gun,and a test experiment of a medium-caliber electromagnetic launcher powered by pulse formation network(PFN)is carried out.Various test methods such as spectrometer,fiber grating and high-speed camera are used to test several parameters such as muzzle initial velocity,transient magnetic field strength and stress-strain of rail.Combining the simulation results and experimental data,the damage condition of the contact surface is analyzed. 展开更多
关键词 Internal ballistic modeling electromagnetic rail gun Multi-physics field coupling Experimental validation PFN
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Constructing Built-In Electric Fields with Semiconductor Junctions and Schottky Junctions Based on Mo-MXene/Mo-Metal Sulfides for Electromagnetic Response
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作者 Xiaojun Zeng Xiao Jiang +2 位作者 Ya Ning Yanfeng Gao Renchao Che 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第10期453-473,共21页
The exploration of novel multivariate heterostructures has emerged as a pivotal strategy for developing high-performance electromagnetic wave(EMW)absorption materials.However,the loss mechanism in traditional heterost... The exploration of novel multivariate heterostructures has emerged as a pivotal strategy for developing high-performance electromagnetic wave(EMW)absorption materials.However,the loss mechanism in traditional heterostructures is relatively simple,guided by empirical observations,and is not monotonous.In this work,we presented a novel semiconductor-semiconductor-metal heterostructure sys-tem,Mo-MXene/Mo-metal sulfides(metal=Sn,Fe,Mn,Co,Ni,Zn,and Cu),including semiconductor junctions and Mott-Schottky junctions.By skillfully combining these distinct functional components(Mo-MXene,MoS_(2),metal sulfides),we can engineer a multiple heterogeneous interface with superior absorption capabilities,broad effective absorption bandwidths,and ultrathin matching thickness.The successful establishment of semiconductor-semiconductor-metal heterostructures gives rise to a built-in electric field that intensifies electron transfer,as confirmed by density functional theory,which collaborates with multiple dielectric polarization mechanisms to substantially amplify EMW absorption.We detailed a successful synthesis of a series of Mo-MXene/Mo-metal sulfides featuring both semiconductor-semiconductor and semiconductor-metal interfaces.The achievements were most pronounced in Mo-MXene/Mo-Sn sulfide,which achieved remarkable reflection loss values of-70.6 dB at a matching thickness of only 1.885 mm.Radar cross-section calculations indicate that these MXene/Mo-metal sulfides have tremendous potential in practical military stealth technology.This work marks a departure from conventional component design limitations and presents a novel pathway for the creation of advanced MXene-based composites with potent EMW absorption capabilities. 展开更多
关键词 Semiconductor-semiconductor-metal heterostructure Semiconductor junctions Mott-Schottky junctions Built-in electric field electromagnetic wave absorption
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Electromagnetic fields in ultra-peripheral relativistic heavy-ion collisions
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作者 Jie Zhao Jin-Hui Chen +1 位作者 Xu-Guang Huang Yu-Gang Ma 《Nuclear Science and Techniques》 SCIE EI CAS CSCD 2024年第2期103-109,共7页
Ultra-peripheral heavy-ion collisions(UPCs)offer unique opportunities to study processes under strong electromagnetic fields.In these collisions,highly charged fast-moving ions carry strong electromagnetic fields that... Ultra-peripheral heavy-ion collisions(UPCs)offer unique opportunities to study processes under strong electromagnetic fields.In these collisions,highly charged fast-moving ions carry strong electromagnetic fields that can be effectively treated as photon fluxes.The exchange of photons can induce photonuclear and two-photon interactions and excite ions.This excitation of the ions results in Coulomb dissociation with the emission of photons,neutrons,and other particles.Additionally,the electromagnetic fields generated by the ions can be sufficiently strong to enforce mutual interactions between the two colliding ions.Consequently,the two colliding ions experience an electromagnetic force that pushes them in opposite directions,causing a back-to-back correlation in the emitted neutrons.Using a Monte Carlo simulation,we qualitatively demonstrate that the above electromagnetic effect is large enough to be observed in UPCs,which would provide a clear means to study strong electromagnetic fields and their effects. 展开更多
关键词 electromagnetic fields Neutrons Ultra-peripheral relativistic heavy-ion collisions(UPC)
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The Pairing Analysis Improvement of Magnetized Structure in Electromagnetic Bulging Process in Case of Tube with Field Shaper
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作者 Blaise Kevine Lenz Soronga Zhanqian Zhan +6 位作者 Jing Liu Jonas Asamoah Mohamed Bangali Bangura Matala Makiese N’kodia Kambani Chrionie Md Jobayer Hossain Yongdong Chen 《Journal of Electromagnetic Analysis and Applications》 2024年第4期43-67,共25页
In the current practical science, the accuracy in the formability of metal alloys being the goal when using electromagnetic forming (EMF) technology, which is a high-speed processing technology that uses Lorentz force... In the current practical science, the accuracy in the formability of metal alloys being the goal when using electromagnetic forming (EMF) technology, which is a high-speed processing technology that uses Lorentz forces to achieve plastic deformation of sheet metal;according to the previous analysis, the results have shown that in most cases, the Lorentz force acting on the workpiece (metal) is not uniform, there are uneven axial deformations of the metal plates which prevent the rapid advancement of today’s technology. In this article, we presented some advanced analyzes which will lead us to improve the technical solution for the problems of non-uniform axial deformations of the metals in the traditional tube electromagnetic forming technology (EMF). A field shaper is used as a practical forming tool to influence the magnetic field and magnetic pressure distribution, thereby improving the forming ability and result during the electromagnetic forming (EMF) process and we see that induced eddy current control is realized by changing the structural parameters of the magnetic field shaper;which improves the strength and controllability of the magnetic force that acts on the workpiece;thereby a greater radial magnetic pressure can be achieved with field shaper than the case without it;the field shaper regulates the electromagnetic force, the distribution of the magnetic pressure decreases, and the uniform force area of the tube increases which effectively enhances the uniform range of the pipe electromagnetic bulging and the electromagnetic induction coupling between the coil and the metallic workpiece is generally required to produce the Lorentz forces. Using COMSOL Multiphysics® simulation software helped us to accurately represent the real world, simulating multiple physical effects that happened in this model during the process. 展开更多
关键词 electromagnetic Forming field Shaper Lorentz Force Magnetic Pressure Distribution
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Characteristics of electromagnetic vector field generated from rock fracturing 被引量:1
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作者 Menghan Wei Dazhao Song +3 位作者 Xueqiu He Quan Lou Liming Qiu Zhenlei Li 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2023年第2期457-466,共10页
Rock fracturing is often accompanied by electromagnetic phenomenon.As a vector field,in addition to the intensity that is widely concerned,the generated electromagnetic field also has obvious direction-ality.To this e... Rock fracturing is often accompanied by electromagnetic phenomenon.As a vector field,in addition to the intensity that is widely concerned,the generated electromagnetic field also has obvious direction-ality.To this end,a set of electromagnetic antennas capable of simultaneous three-axis measurement is used to monitor the electromagnetic vector field generated from rock fracturing based on Brazilian tests.The signal amplitude on each axis can represent the magnitude of actual magnetic flux density component on the three axes.The intensity and directional characteristics of electromagnetic signals received at different positions are studied using vector synthesis.The directionality of electromagnetic radiation measured using a three-axis electromagnetic antenna shows that the direction of the magnetic flux intensity generated by rock fracturing tends to be parallel to the crack surface,and the measured signal intensity is greater in a direction closer to the crack surface. 展开更多
关键词 electromagnetic radiation DIRECTIONALITY Vector field Rock fracturing
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Flashover Probability of Wind Turbine Blade and Impact of Strong Electromagnetic Pulse from Lightning Strikes on Wind Turbine Safety
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作者 Lixin YAO Bin XIAO +5 位作者 Jianwen ZHANG Weixiang FENG Renhong GUO Zengru YANG Chunliang ZHANG Hui YANG 《Meteorological and Environmental Research》 2024年第1期62-66,共5页
This paper systematically studies the flashover probability of wind turbine blade lightning arrester and the impact of strong electromagnetic pulses on the local and surrounding wind turbines during lightning strikes.... This paper systematically studies the flashover probability of wind turbine blade lightning arrester and the impact of strong electromagnetic pulses on the local and surrounding wind turbines during lightning strikes.The research results indicate that the flashover probability of direct lightning strikes by the wind turbine blade lightning arrester is almost negligible,and the strong electromagnetic pulse of wind turbine blade during lightning strikes has a serious impact on the electronic equipment of the machine,while the impact on the surrounding wind turbine is relatively small.At the same time,the calculation formula for the reflection of lightning current on the carbon brush between the wind turbine hub and the engine compartment during the flashing of the wind turbine blades is provided,and the calculation method for calculating the spatial gradient distribution of electromagnetic field intensity using Biot-Savart Law theorem is applied.The limitations of using wind turbine blades for lightning protection are pointed out,and a technical route for achieving wind turbine lightning safety is proposed,which can be used as a reference for wind turbine lightning protection technicians. 展开更多
关键词 Wind turbine Flashover probability of blade lightning arrester Spatial gradient of electromagnetic field intensity Technical route
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Long-term radiofrequency electromagnetic fields exposure attenuates cognitive dysfunction in 5×FAD mice by regulating microglial function
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作者 Yeonghoon Son Hye-Jin Park +3 位作者 Ye Ji Jeong Hyung-Do Choi Nam Kim Hae-June Lee 《Neural Regeneration Research》 SCIE CAS CSCD 2023年第11期2497-2503,共7页
We have previously found that long-term effects of exposure to radiofrequency electromagnetic fields in 5xFAD mice with severe late-stage Alzheimer’s disease reduced both amyloid-βdeposition and glial activation,inc... We have previously found that long-term effects of exposure to radiofrequency electromagnetic fields in 5xFAD mice with severe late-stage Alzheimer’s disease reduced both amyloid-βdeposition and glial activation,including microglia.To examine whether this therapeutic effect is due to the regulation of activated microglia,we analyzed mic roglial gene expression profiles and the existence of microglia in the brain in this study.5xFAD mice at the age of 1.5 months were assigned to sham-and radiofrequency electromagnetic fields-exposed groups and then animals were exposed to 1950 MHz radiofrequency electromagnetic fields at a specific absorption rate of 5 W/kg for 2 hours/day and 5 days/week for 6 months.We conducted behavioral tests including the object recognition and Y-maze tests and molecular and histopathological analysis of amyloid precursor protein/a myloid-beta metabolism in brain tissue.We confirmed that radiofrequency electromagnetic field exposure for 6 months ameliorated cognitive impairment and amyloid-βdeposition.The expression levels of Iba1(pan-microglial marker)and colony-stimulating factor 1 receptor(CSF1R;regulates microglial prolife ration)in the hippocampus in 5xFAD mice treated with radiofrequency electromagnetic fields were significantly reduced compared with those of the sham-exposed group.Subsequently,we analyzed the expression levels of genes related to mic rogliosis and microglial function in the radiofrequency electromagnetic fields-exposed group compared to those of a CSF1R inhibitor(PLX3397)-treated group.Both radiofrequency electromagnetic fields and PLX3397 suppressed the levels of genes related to microgliosis(Csf1r,CD68,and Ccl6)and pro-inflammatory cytokine interleukin-1β.N otably,the expression levels of genes related to mic roglial function,including Trem2,Fcgr1α,Ctss,and Spi1,were decreased after long-term radiofrequency electromagnetic field exposure,which was also observed in response to microglial suppression by PLX3397.These results showed that radiofrequency electromagnetic fields ameliorated amyloid-βpathology and cognitive impairment by suppressing amyloid-βdeposition-induced microgliosis and their key regulator,CSF1R. 展开更多
关键词 5×FAD Alzheimer’s disease CSF1R long term exposure microglial function NEUROINFLAMMATION radiofrequency electromagnetic fields therapeutic effect
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Electric field intensity measurement by using doublet electromagnetically induced transparency of cold Rb Rydberg atoms
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作者 宫廷 师帅 +7 位作者 姬中华 郭古青 孙小聪 田亚莉 邱选兵 李传亮 赵延霆 贾锁堂 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第10期405-409,共5页
We demonstrate a simple method to measure electric field intensity by using doublet electromagnetically induced transparency(EIT) spectra of cold Rb Rydberg atoms, where the frequency of the coupling laser does not ne... We demonstrate a simple method to measure electric field intensity by using doublet electromagnetically induced transparency(EIT) spectra of cold Rb Rydberg atoms, where the frequency of the coupling laser does not need to be locked. Based on the Stark splitting of the Rb Rydberg state, 10D_(3/2), under electric fields and the corresponding calculated polarizabilities, the real electric field intensity is calculated using the difference in radio-frequency diffraction between two acousto-optic modulators, which acts as a frequency criterion that allows us to measure the electrical field without locking the coupling laser. The value measured by this simple method shows a good agreement with our previous work [Opt.Express 29 1558(2021)] where the frequency of the coupling laser needs to be locked with an additional EIT spectrum based on atom vapor and a proportional–integral–differential feedback circuit. Our presented method can also be extended to the measurement of electric field based on hot Rydberg atom vapor, which has application in industry. 展开更多
关键词 doublet electromagnetically induced transparency(EIT) Aulter–Townes(AT)splitting Rydberg atom electric field measurement
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Analysis and Simulation of the Influence of Electromagnetic Fields on Living Beings near HV Power Lines Using the FDTD Method
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作者 Anthony Bassesuka Sandoka Nzao 《Open Journal of Applied Sciences》 2023年第12期2343-2359,共17页
Recent decades have seen rapid advances in the field of electrical engineering, such that our environment has become a sea of electrical and magnetic signals, raising questions about the possible effects of low-freque... Recent decades have seen rapid advances in the field of electrical engineering, such that our environment has become a sea of electrical and magnetic signals, raising questions about the possible effects of low-frequency electromagnetic fields on the environment and which are capable of modifying and destroying our ecosystem. Particular interest was given in this article due to a massive influx of population living near high voltage lines. The analysis and simulation of the influence of low frequency electromagnetic fields on living beings in the vicinity of high voltage sources 132 kV and 220 kV in urban areas in DR Congo is the subject of our research with a view to estimating the level of exposure of humans to low frequency electromagnetic fields. To carry out our research, we used the classic method of analyzing the field produced near a high voltage line based on Maxwell’s image theory, the Maxwell-Gauss theorem and Maxwell-Ampère theorem to model and quantify low-frequency electromagnetic fields in the vicinity of high-voltage lines. The 2D FDTD numerical formulation was developed from telegraphers’ equations and allowed us to obtain models of current and voltage induced by electromagnetic fields on living beings below and near HV lines. The different simulations carried out on the proposed models illustrate the effects of the electrical and geometric parameters of the pylons on the distribution of the electromagnetic field in the vicinity of the HV lines. The results obtained were compared to the safety limits recommended by the standards. 展开更多
关键词 Low Frequency electromagnetic field Modeling field and Health Maxwell’s Equations FDTD Method electromagnetic Compatibility High Voltage Line
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Effects of 60 Hz electromagnetic field exposure on testiculargerm cell apoptosis in mice 被引量:23
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作者 Jin Sang Lee Sang Seok Ahn +2 位作者 Kyeong Cheon Jung Yoon-Won Kim Sang Kon Lee 《Asian Journal of Andrology》 SCIE CAS CSCD 2004年第1期29-34,共6页
Aim: To evaluate the effects of 60 Hz extremely low frequency (ELF) elelctromagnetic field (EMF) exposure on germ cell apoptosis in the testis of mice. Methods: Adult male BALB/c mice (7 weeks of age) were exposed to ... Aim: To evaluate the effects of 60 Hz extremely low frequency (ELF) elelctromagnetic field (EMF) exposure on germ cell apoptosis in the testis of mice. Methods: Adult male BALB/c mice (7 weeks of age) were exposed to a 60 Hz EMF of 0.1 mT or 0.5 mT for 24 h/day. A sham-exposed group served as the control. After 8 weeks of exposure, the mice were sacrificed. Germ cell apoptosis in the testis was assessed by histopathological examination, the terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling assay (TUNEL) and flow cytometric examination of isolated spermatogenic cells stained with 7 aminoactinomycin D (7-AAD). Results: EMF exposure did not significantly affect the body and testis weights, but significantly increased the incidence of germ cell death. The distinguishing morphological feature of EMF exposure was a decrement in the number of well organized seminiferous tubules. Quantitative analysis of TUNEL-positive germ cells showed a significantly higher apoptotic rate in the 0.5 mT exposed mice than that in the sham controls (P<0.05), while the difference between the two exposed groups was insignificant. The TUNEL-positive cells were mainly spermatogonia. In flow cytometry analysis, the percentage of live cells [forward scatter count (FSC)high7-AAD-] was lower in the exposed groups than that in the controls (Figure 5A), but the decrease in viability was not statistically significant. Conclusion: Continuous exposure to ELF EMF may induce testicular germ cell apoptosis in mice. 展开更多
关键词 electromagnetic field TESTIS apoptosis TUNEL flow cytometry 7-aminoactinomycin D
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Effect of Electromagnetic Fields on Proliferation and Differentiation of Cultured Mouse Bone Marrow Mesenchymal Stem Cells 被引量:17
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作者 吴华 任凯 +2 位作者 赵文春 葛保剑 彭松林 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2005年第2期185-187,共3页
Summary: In order to study the effects of electromagnetic fields (EMFs) on proliferation, differentiation and intercellular cyclic AMP (cAMP) in mouse bone marrow mesenchymal stem cells (MSCs) in vitro, the mouse bone... Summary: In order to study the effects of electromagnetic fields (EMFs) on proliferation, differentiation and intercellular cyclic AMP (cAMP) in mouse bone marrow mesenchymal stem cells (MSCs) in vitro, the mouse bone MSCs were isolated and cultured in vitro. The third passage MSCs were divided into 4 groups and stimulated with EMFs. The cellular proliferation (MTT), the cellular differentiation (alkaline phosphatase activity, ALP), and the intercellular cAMP level were investigated at different time points. The results showed that EMF (50Hz pulse burst 2 mT peak) inhibited the cellular proliferation (P<0.05), enhanced the cellular differentiation (P<0.05), and increased the intercellular cAMP level (P<0.01) in the early time of the stimulation (1-3 days), but the intercellular cAMP level did not increased further in the later days. We are led to conclude that the cAMP may be involved in the mediation of the growth inhibitory and differentiation-inducing signals of specific EMFs in vitro. 展开更多
关键词 electromagnetic field cyclic AMP alkaline phosphatase marrow mesenchymal stem cells
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Effect of low-frequency electromagnetic field on the as-cast microstructure of a new super high strength aluminum alloy by horizontal continuous casting 被引量:8
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作者 Yubo ZUO Jianzhong CUI +3 位作者 Yang WANG Xiaotao LIU Zhihao ZHAO Haitao Zhang 《China Foundry》 SCIE CAS 2005年第1期48-51,共4页
The super high strength aluminum alloy ingots with 100 mm in diameter were cast by the process of low-frequency electromagnetic horizontal continuous casting (LFEHC) and the effect of electromagnetic field on the as-c... The super high strength aluminum alloy ingots with 100 mm in diameter were cast by the process of low-frequency electromagnetic horizontal continuous casting (LFEHC) and the effect of electromagnetic field on the as-cast microstructure was studied. Results show that microstructure of the sample prepared by the LFEHC process was greatly refined. Microstructures at the border and the center of the ingots were fine, uniform and rosette-shaped. Electromagnetic frequency plays a key role in microstructure refining. Fine and uniform microstructures can be obtained with optimal electromagnetic frequency. In this experiment, under a frequency of 30 Hz the microstructure was the finest and the most uniform. 展开更多
关键词 LOW-FREQUENCY electromagnetic field HORIZONTAL continuous CASTING microstructure AL-ZN-MG-CU alloy
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Experimental studies and phase field modeling of microstructure evolution during solidification with electromagnetic stirring 被引量:8
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作者 P.GERALD TENNYSON P.KUMAR +2 位作者 H.LAKSHMI G.PHANIKUMAR P.DUTTA 《中国有色金属学会会刊:英文版》 CSCD 2010年第S3期774-780,共7页
Thixocasting requires manufacturing of billets with non-dendritic microstructure.Aluminum alloy A356 billets were produced by rheocasting in a mould placed inside a linear electromagnetic stirrer.Subsequent heat treat... Thixocasting requires manufacturing of billets with non-dendritic microstructure.Aluminum alloy A356 billets were produced by rheocasting in a mould placed inside a linear electromagnetic stirrer.Subsequent heat treatment was used to produce a transition from rosette to globular microstructure.The current and the duration of stirring were explored as control parameters.Simultaneous induction heating of the billet during stirring was quantified using experimentally determined thermal profiles.The effect of processing parameters on the dendrite fragmentation was discussed.Corresponding computational modeling of the process was performed using phase-field modeling of alloy solidification in order to gain insight into the process of morphological changes of a solid during this process.A non-isothermal alloy solidification model was used for simulations.The morphological evolution under such imposed thermal cycles was simulated and compared with experimentally determined one.Suitable scaling using the thermosolutal diffusion distances was used to overcome computational difficulties in quantitative comparison at system scale.The results were interpreted in the light of existing theories of microstructure refinement and globularisation. 展开更多
关键词 electromagnetic STIRRING NON-DENDRITIC phase field modeling microstructure
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Low-frequency pulsed electromagnetic field pretreated bone marrow-derived mesenchymal stem cells promote the regeneration of crush-injured rat mental nerve 被引量:11
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作者 NaRi Seo Sung-Ho Lee +5 位作者 Kyung Won Ju JaeMan Woo BongJu Kim SoungMin Kim Jeong Won Jahng Jong-Ho Lee 《Neural Regeneration Research》 SCIE CAS CSCD 2018年第1期145-153,共9页
Bone marrow-derived mesenchymal stem cells (BMSCs) have been shown to promote the regeneration of injured peripheral nerves. Pulsed electromagnetic field (PEMF) reportedly promotes the proliferation and neuronal d... Bone marrow-derived mesenchymal stem cells (BMSCs) have been shown to promote the regeneration of injured peripheral nerves. Pulsed electromagnetic field (PEMF) reportedly promotes the proliferation and neuronal differentiation of BMSCs. Low-frequency PEMF can induce the neuronal differentiation of BMSCs in the absence of nerve growth factors. This study was designed to investigate the effects of low-frequency PEMF pretreatment on the proliferation and function of BMSCs and the effects of low-frequency PEMF pre-treated BMSCs on the regeneration of injured peripheral nerve using in vitro and in vivo experiments.In in vitro experiments, quantitative DNA analysis was performed to determine the proliferation of BMSCs, and reverse transcription-polymerase chain reaction was performed to detect S100 (Schwann cell marker), glial fibrillary acidic protein (astrocyte marker), and brain-derived neurotrophic factor and nerve growth factor (neurotrophic factors) mRNA expression. In the in vivo experiments, rat models of crush-injured mental nerve established using clamp method were randomly injected with low-frequency PEMF pretreated BMSCs, unpretreated BMSCs or PBS at the injury site (1 × 106 cells). DiI-labeled BMSCs injected at the injury site were counted under the fluorescence microscope to determine cell survival. One or two weeks after cell injection, functional recovery of the injured nerve was assessed using the sensory test with von Frey filaments. Two weeks after cell injection, axonal regeneration was evaluated using histomorphometric analysis and retrograde labeling of trigeminal ganglion neurons. In vitro experiment results revealed that low-frequency PEMF pretreated BMSCs proliferated faster and had greater mRNA expression of growth factors than unpretreated BMSCs. In vivo experiment results revealed that compared with injection of unpretreated BMSCs, injection of low-frequency PEMF pretreated BMSCs led to higher myelinated axon count and axon density and more DiI-labeled neurons in the trigeminal ganglia, contributing to rapider functional recovery of injured mental nerve. These findings suggest that low-frequency PEMF pretreatment is a promising approach to enhance the efficacy of cell therapy for peripheral nerve injury repair. 展开更多
关键词 nerve regeneration mesenchymal stem cells low-frequency pulsed electromagnetic field peripheral nerve injury crush-injured mental nerve
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Evaluation of spermatogenesis and fertility in F1 male rats after in utero and neonatal exposure to extremely low frequency electromagnetic fields 被引量:5
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作者 M.K.Chung S.J.Lee +4 位作者 Y.B.Kim S.C.Park D.H.Shin S.H.Kim J.C.Kim 《Asian Journal of Andrology》 SCIE CAS CSCD 2005年第2期189-194, ,共6页
Aim:To determine whether in utero and neonatal exposure to a 60 Hz extremely low frequency electromagnetic field (EMF) results in spermatotoxicity and reproductive dysfunction in the F1 offspring of rats.Methods:Age-m... Aim:To determine whether in utero and neonatal exposure to a 60 Hz extremely low frequency electromagnetic field (EMF) results in spermatotoxicity and reproductive dysfunction in the F1 offspring of rats.Methods:Age-matched, pregnant Sprague-Dawley rats were exposed continuously (21 h/day) to a 60 Hz EMF at field strengths of 0 (sham control),5,83.3 or 500 μT from day 6 of gestation through to day 21 of lactation.The experimentally generated magnetic field was monitored continuously (uninterrupted monitoring over the period of the study) throughout the study.Results:No exposure-related changes were found in exposed or sham-exposed animals with respect to the anogenital distance,preputial separation,testis weight,testicular histology,sperm count,daily sperm production, sperm motility,sperm morphology and reproductive capacity of F1 offspring.Conclusion:Exposure of Sprague- Dawley rats to a 60 Hz EMF at field strengths of up to 500 μT from day 6 of gestation to day 21 of lactation did not produce any detectable alterations in offspring spermatogenesis and fertility. 展开更多
关键词 SPERMATOGENESIS electromagnetic fields prenatal exposure postnatal exposure rat
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THREE-DIMENSIONAL CHARACTERISTICS AND HOMOGENIZATION OF ELECTROMAGNETIC FIELD IN SOFT-CONTACT CONTINUOUS CASTING MOLD 被引量:5
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作者 A. Y. Deng, G.L. Jia and J.C. He (Key Laboratory for Electromagnetic Processing of Materials, Ministry of Education, Northeastern University, Shenyang 110004, China) 《Acta Metallurgica Sinica(English Letters)》 SCIE EI CAS CSCD 2001年第2期137-142,共6页
The three-dimensional electromagnetic characteristics and non-uniform distribution of electromagnetic field in soft-contact continuous casting mold have been analyzed by numerical simulation. The results show that the... The three-dimensional electromagnetic characteristics and non-uniform distribution of electromagnetic field in soft-contact continuous casting mold have been analyzed by numerical simulation. The results show that the maximum electromagnetic flux density is found in front of slit; the electromagnetic flux density becomes large as the coil current and slit number increase. In a certain frequency range, the electromagnetic flux density increases with the increase of frequency and the frequency range is different with the change of azimuthal position along the inner wall of mold. The uniformity of electromagnetic field is influenced mainly by frequency and mold structure parameters. Increasing slit number and adjusting slit arrangement position can improve the electromagnetic flux density and the uniformity of electromagnetic field. For a soft-contact mold with 16 slits, when frequency is 20 kHz, the optimal slit arrangement parameter is a:b=1:2, c=0. 展开更多
关键词 Computer simulation electromagnetic fields Magnetic properties MOLDS Optimization Three dimensional
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Electromagnetic Field Change the Expression of Osteogenesis Genes in Murine Bone Marrow Mesenchymal Stem Cells 被引量:11
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作者 赵东明 吴华 +2 位作者 李峰 李锐 陶超雄 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2008年第2期152-155,共4页
In order to identify the differentially expressing gene of bone marrow mesenchymal stem cells (MSCs) stimulated by electromagnetic field (EMF) with osteogenesis microarray analysis, the bone marrow MSCs of SD rats... In order to identify the differentially expressing gene of bone marrow mesenchymal stem cells (MSCs) stimulated by electromagnetic field (EMF) with osteogenesis microarray analysis, the bone marrow MSCs of SD rats were isolated and cultured in vitro. The third-passage cells were stimulated by EMFs and total RNA was extracted, purified and then used for the synthesis of cDNA and cRNA. The cRNA of stimulated group and the control group was hybridized with the rat oligo osteogenesis microarray respectively. The hybridization signals were acquired by using X-ray film after chemiluminescent detection and the data obtained were analyzed by employing the web-based completely integrated GEArray Expression Analysis Suite. RT-PCR was used to identify the target genes: Bmp1, Bmp7, Egf and Egfr. The results showed that 19 differentially expressing genes were found between the stimulated group and the control group. There were 6 up-regulated genes and 13 down-regulated genes in the stimulated group. Semi-quantitative RT-PCR confirmed that the expressions of Bmpl, Bmp7 mRNA of the stimulated group were up-regulated (P〈0.05) and those of Egf, Egfr were down-regulated (P〈0.05). It was suggested that the gene expression profiles of osteogenesis of the bone marrow MSCs were changed after EMF treatment. It is concluded that the genes are involved in skeletal development, bone mineral metabolism, cell growth and differentiation, cell adhesion etc. 展开更多
关键词 electromagnetic fields osteogenesis microarray analysis bone marrow mesenchymal stem cells
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The Effects of High-intensity Pulsed Electromagnetic Field on Proliferation and Differentiation of Neural Stem Cells of Neonatal Rats in vitro 被引量:8
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作者 蒙德鹏 许涛 +2 位作者 郭风劲 印卫锋 彭涛 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2009年第6期732-736,共5页
The effects of high-intensity pulsed electromagnetic stimulation (HIPEMS) on proliferation and differentiation of neonatal rat neural stem cells in vitro were investigated. Neural stem cells derived from neonatal ra... The effects of high-intensity pulsed electromagnetic stimulation (HIPEMS) on proliferation and differentiation of neonatal rat neural stem cells in vitro were investigated. Neural stem cells derived from neonatal rats were exposed to 0.1 Hz, 0.5–10 Tesla (T) [8 groups of B–I, respectively], 5 stimuli of HIPEMF. The sham exposure controls were correspondingly established. Inverted phase contrast microscope was used to observe the cultured cells, MTT assay to detect the viability of the cells as expressed by absorbance (A) value, and flow cytometry to measure differentiation of neural stem cells. The results showed that A values of neural stem cells in both 3.0 T and 4.0 T groups were significantly higher than the other groups 24 to 168 h post HPEMS, indicating a strong promotion of the growth of neural stem cells (P〈0.05). The A values of neural stem cells in the 6.0 T, 8.0 T, and 10.0 T groups were lower than the sham exposure control group, indicating a restraint of the growth of neural stem cells. The rate of neuron-specific enolase-positive neurons revealed by flow cytometry in HPEMS groups was the same as that in control group (P〉0.05). It was suggested that 0.1 Hz, 5 pulses stimulation of HPEMS within certain scale of intensity (0.5–10.0 T), significantly promoted the growth of neural stem cells with the rational intensity being 4.0 T. 展开更多
关键词 neural stem cells high-intensity pulsed electromagnetic field cell proliferation RAT
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Effect of electromagnetic force on melt induced by traveling magnetic field 被引量:5
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作者 苏彦庆 徐严谨 +2 位作者 赵雷 郭景杰 傅恒志 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2010年第4期662-667,共6页
A new apparatus was designed to measure the electromagnetic force and a computational study of the traveling magnetic field(TMF)and its application to the Ga-In-Sn melt(with low melting point),then the forces on Al,Mg... A new apparatus was designed to measure the electromagnetic force and a computational study of the traveling magnetic field(TMF)and its application to the Ga-In-Sn melt(with low melting point),then the forces on Al,Mg,and Li melt,were simulated. The result show that the electromagnetic force on the melt increases linearly with the increasing length of the melt in the TMF.The TMF-induced Lorentz force increases with increasing frequency,and then decreases.The maximum value is obtained when the current frequency is 160 Hz,over that frequency the force decreases rapidly.When the iron-core is activated,the force increases when the melt closes to the iron-core.The Lorentz forces have inversely-proportional relationships with the electrical resistivity,the dfx/dρdecreases and the dfy/dρincreases with the increasing electrical resistivity(df/dρis the slope of the Lorentz force profile). 展开更多
关键词 electromagnetic force traveling magnetic field Ga-In-Sn melt molten metal
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